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MTATASDDEAVTALALSAAKGNGRALEAFIKATQQDVWRFVAYLSDVGSADDLTQETFLRAIGAIPRFSA RSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARGFEDLVEVTTMIADLTTDQREALL LTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLADAEPDDLTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2095 | sigC | - | 100% (185) | RNA polymerase sigma factor SigC |
| M. bovis AF2122 / 97 | Mb1253 | sigE | 1e-09 | 31.06% (132) | RNA polymerase sigma factor SigE |
| M. bovis AF2122 / 97 | Mb3448c | sigD | 3e-09 | 29.71% (175) | RNA polymerase sigma factor SigD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5063 | - | 5e-11 | 32.12% (137) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv2069 | sigC | 1e-101 | 100.00% (185) | RNA polymerase sigma factor SigC |
| M. leprae Br4923 | MLBr_01448 | - | 7e-79 | 81.22% (181) | RNA polymerase sigma factor SigC |
| M. abscessus ATCC 19977 | MAB_3428c | - | 2e-60 | 62.84% (183) | RNA polymerase sigma-C factor |
| M. marinum M | MMAR_3051 | sigC | 7e-81 | 83.52% (182) | RNA polymerase sigma factor, SigC |
| M. avium 104 | MAV_2426 | - | 5e-82 | 85.00% (180) | RNA polymerase sigma factor SigC |
| M. smegmatis MC2 155 | MSMEG_6931 | - | 6e-11 | 30.39% (181) | RNA polymerase sigma-70 factor |
| M. thermoresistible (build 8) | TH_1729 | sigC | 3e-59 | 64.25% (179) | PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC |
| M. ulcerans Agy99 | MUL_2295 | sigC | 5e-81 | 83.52% (182) | RNA polymerase sigma factor SigC |
| M. vanbaalenii PYR-1 | Mvan_2297 | - | 7e-11 | 31.03% (145) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 MTPGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAI
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 AAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPAS
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 ASGVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVA
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 RERVGSRRPGSSDATADAGFAAWAADAPAGRRRGHLRPINRAAPDPTASS
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5063|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 ----------------MTATASDDEAVTALALSAAKGNGRALEAFIKATQ
Rv2069|M.tuberculosis_H37Rv ----------------MTATASDDEAVTALALSAAKGNGRALEAFIKATQ
MLBr_01448|M.leprae_Br4923 -----------------MIASSGDEAVTDLALAAARGSKRALEAFIKATQ
MAV_2426|M.avium_104 TTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARALEAFIKATQ
MMAR_3051|M.marinum_M -----------------MTTSPDDEAVTALALAAADGDARAFEAFIKATQ
MUL_2295|M.ulcerans_Agy99 ---------------MPMTTSPDDEAVTALALAAADGDARAFEAFIKATQ
MAB_3428c|M.abscessus_ATCC_199 -----------------MATGTDDEQLLELALSAGRGDQSALESLVKATQ
TH_1729|M.thermoresistible__bu ------------------VGLRDDDRVTRLALAAGRGDPAALEQFIRATQ
MSMEG_6931|M.smegmatis_MC2_155 ------------MGRGEFAGAAHTRSDAELLAAHVAGDRYAFEELVLRHH
Mflv_5063|M.gilvum_PYR-GCK ------------------MSADSEGAASEGAVPEGLDAPSALLALYDEAL
Mvan_2297|M.vanbaalenii_PYR-1 ------------MRRSSIQWNQQPDNLFGGPVMDSPPEDTVLQRFERDVL
.: :
Mb2095|M.bovis_AF2122/97 ---QDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLA
Rv2069|M.tuberculosis_H37Rv ---QDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLA
MLBr_01448|M.leprae_Br4923 ---QDVWRFVAYLS-DVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLA
MAV_2426|M.avium_104 ---QDVWRFVAYLC-DAGSADDLTQETFLRAIGAIERFSGRSSARTWLLS
MMAR_3051|M.marinum_M ---QDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLA
MUL_2295|M.ulcerans_Agy99 ---QDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLA
MAB_3428c|M.abscessus_ATCC_199 ---GDVWRFVAYLA-DSGVADDLTQETYLRALGALPRFAGRSTVRTWLLS
TH_1729|M.thermoresistible__bu ---RDVWRTVAYLA-DPGSADDLTQETFLRAIRSLPKFNGRSSARTWLLS
MSMEG_6931|M.smegmatis_MC2_155 ---RQLRRLAYLTSNHLDDADDAVQEALLKAHRTAATFRFDCAVSSWLYR
Mflv_5063|M.gilvum_PYR-GCK ---PAVYGYFVRRCGDRGTAEDLTSETFLAAMDAARKPSPPDLSVRWLIG
Mvan_2297|M.vanbaalenii_PYR-1 PLLDQLYRAARRYTGSVADAEDLVQETMVKAYGGFHRFEDGTNVRAWLLR
: *:* ..*: : * **
Mb2095|M.bovis_AF2122/97 IARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARG-------------
Rv2069|M.tuberculosis_H37Rv IARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARG-------------
MLBr_01448|M.leprae_Br4923 IARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARG-------------
MAV_2426|M.avium_104 IARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARG-------------
MMAR_3051|M.marinum_M IARRVVADHIRHLQARPRAAHGVDPELLLDRGRRARG-------------
MUL_2295|M.ulcerans_Agy99 IARRVVADHIRHLQARPRAAHGVDPELLLDRGRRARG-------------
MAB_3428c|M.abscessus_ATCC_199 IARRVVADHIRHLKSRPRIAHGADLEEAS-LRRPTHR-------------
TH_1729|M.thermoresistible__bu IARRVVVDQIRHNQSRPRTSYAVDVHTVLDKRRPDGR-------------
MSMEG_6931|M.smegmatis_MC2_155 IVVNACLDRLRRTRTQPSATHYVELGHVNHLRDPAADPA---------PR
Mflv_5063|M.gilvum_PYR-GCK VARHKLADHYRRRWDRFATPVAELPEPADPADEWDAE-------------
Mvan_2297|M.vanbaalenii_PYR-1 IMTNTWIKSYRRAQCRPEEVLSEDITDAQLAGHGRHSSTGLPSAELAALE
: . . *: :
Mb2095|M.bovis_AF2122/97 FEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRV
Rv2069|M.tuberculosis_H37Rv FEDLVEVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRV
MLBr_01448|M.leprae_Br4923 FEDLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRV
MAV_2426|M.avium_104 FEDLVEVTTMIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRV
MMAR_3051|M.marinum_M FEDLVEVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRV
MUL_2295|M.ulcerans_Agy99 FEDLVEVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRV
MAB_3428c|M.abscessus_ATCC_199 FEELVELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTIRSRV
TH_1729|M.thermoresistible__bu FEDIVEIKLLLDGLDTDRRHALLLTQVLGLSYAEAAEVCGCAVGTIRSRV
MSMEG_6931|M.smegmatis_MC2_155 VTTAITVERALLQLPVDQRAAVVAVDMQGYSVAETARLLGVAEGTIKSRC
Mflv_5063|M.gilvum_PYR-GCK -LDRIVAEQVLTRLSDPHRAVLVLRYMDGCSVPECAELIGRTVHATEALL
Mvan_2297|M.vanbaalenii_PYR-1 ALGDDEVRDALGRLREDQRLVVYYADVEGLRYKEIALILDIPVGTVMSRL
: * :* .: : * : * : . . : :
Mb2095|M.bovis_AF2122/97 ARARDALLADAEPDDLTG--------------
Rv2069|M.tuberculosis_H37Rv ARARDALLADAEPDDLTG--------------
MLBr_01448|M.leprae_Br4923 ARARDALLADTEHNHLTG--------------
MAV_2426|M.avium_104 ARARDALLADGERNDLTG--------------
MMAR_3051|M.marinum_M ARARDALLADNERDDLTG--------------
MUL_2295|M.ulcerans_Agy99 ARARDALLADNERDDLTG--------------
MAB_3428c|M.abscessus_ATCC_199 ARARDELIGWAEPENLTG--------------
TH_1729|M.thermoresistible__bu ARARDDLLQQARPVDRTG--------------
MSMEG_6931|M.smegmatis_MC2_155 ARARAKLARTLQYFDGDEPQPATSAHRGAAHP
Mflv_5063|M.gilvum_PYR-GCK VRARRAFRAMYPEPEGGLS-------------
Mvan_2297|M.vanbaalenii_PYR-1 HRGRRALRSLLVDVATARGYLRDAAAA-----
*.* :