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ATGTDDEQLLELALSAGRGDQSALESLVKATQGDVWRFVAYLADSGVADDLTQETYLRALGALPRFAGRS TVRTWLLSIARRVVADHIRHLKSRPRIAHGADLEEASLRRPTHRFEELVELKSLLAALDDDRREALVLTQ VVGLSYAETADVCGCAIGTIRSRVARARDELIGWAEPENLTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3428c | - | - | 100% (183) | RNA polymerase sigma-C factor |
| M. abscessus ATCC 19977 | MAB_3724c | - | 7e-12 | 32.39% (176) | RNA polymerase sigma factor SigD |
| M. abscessus ATCC 19977 | MAB_1248 | - | 9e-12 | 33.54% (164) | RNA polymerase sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2095 | sigC | 2e-60 | 62.84% (183) | RNA polymerase sigma factor SigC |
| M. gilvum PYR-GCK | Mflv_2200 | - | 4e-11 | 28.16% (174) | RNA polymerase sigma factor SigE |
| M. tuberculosis H37Rv | Rv2069 | sigC | 2e-60 | 62.84% (183) | RNA polymerase sigma factor SigC |
| M. leprae Br4923 | MLBr_01448 | - | 2e-53 | 58.43% (178) | RNA polymerase sigma factor SigC |
| M. marinum M | MMAR_3051 | sigC | 1e-59 | 61.96% (184) | RNA polymerase sigma factor, SigC |
| M. avium 104 | MAV_2426 | - | 4e-61 | 65.19% (181) | RNA polymerase sigma factor SigC |
| M. smegmatis MC2 155 | MSMEG_6931 | - | 2e-14 | 33.33% (168) | RNA polymerase sigma-70 factor |
| M. thermoresistible (build 8) | TH_1729 | sigC | 8e-62 | 64.80% (179) | PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC |
| M. ulcerans Agy99 | MUL_2295 | sigC | 8e-60 | 61.96% (184) | RNA polymerase sigma factor SigC |
| M. vanbaalenii PYR-1 | Mvan_6065 | - | 9e-12 | 30.25% (162) | Fis family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 MTPGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAI
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_6065|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 AAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPAS
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_6065|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 ASGVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVA
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_6065|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK -----------------------------------MTEGARTDTVRTARI
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 RERVGSRRPGSSDATADAGFAAWAADAPAGRRRGHLRPINRAAPDPTASS
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_6931|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_6065|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK DSARSRNENASARVAEHDGSPQGGPHHHLEDPTTTTQAPTSSVSAAAPVA
MMAR_3051|M.marinum_M -----------------MTTSPDDEAVTALALAAADGDARAF---EAFIK
MUL_2295|M.ulcerans_Agy99 ---------------MPMTTSPDDEAVTALALAAADGDARAF---EAFIK
Mb2095|M.bovis_AF2122/97 ----------------MTATASDDEAVTALALSAAKGNGRAL---EAFIK
Rv2069|M.tuberculosis_H37Rv ----------------MTATASDDEAVTALALSAAKGNGRAL---EAFIK
MLBr_01448|M.leprae_Br4923 -----------------MIASSGDEAVTDLALAAARGSKRAL---EAFIK
MAV_2426|M.avium_104 TTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARAL---EAFIK
MAB_3428c|M.abscessus_ATCC_199 -----------------MATGTDDEQLLELALSAGRGDQSAL---ESLVK
TH_1729|M.thermoresistible__bu ------------------VGLRDDDRVTRLALAAGRGDPAAL---EQFIR
MSMEG_6931|M.smegmatis_MC2_155 ---------MGR-GEFAG--AAHTRSDAELLAAHVAGDRYAF---EELVL
Mvan_6065|M.vanbaalenii_PYR-1 ---------MGIFGGTHGRPEQQPRTDAELLAAHVAGDRYAF---EELFH
Mflv_2200|M.gilvum_PYR-GCK APVAAPVSMAHREQFTEAEWVEPTDELTGTAVFDATGDKAAMPSWDELVR
*. *: : :.
MMAR_3051|M.marinum_M ATQQDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLA
MUL_2295|M.ulcerans_Agy99 ATQQDVWRFVAYLS-DAGSADDLTQETFLRAIGAIRRFGGRSSARTWLLA
Mb2095|M.bovis_AF2122/97 ATQQDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLA
Rv2069|M.tuberculosis_H37Rv ATQQDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLA
MLBr_01448|M.leprae_Br4923 ATQQDVWRFVAYLS-DVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLA
MAV_2426|M.avium_104 ATQQDVWRFVAYLC-DAGSADDLTQETFLRAIGAIERFSGRSSARTWLLS
MAB_3428c|M.abscessus_ATCC_199 ATQGDVWRFVAYLA-DSGVADDLTQETYLRALGALPRFAGRSTVRTWLLS
TH_1729|M.thermoresistible__bu ATQRDVWRTVAYLA-DPGSADDLTQETFLRAIRSLPKFNGRSSARTWLLS
MSMEG_6931|M.smegmatis_MC2_155 RHHRQLRRLAYLTSNHLDDADDAVQEALLKAHRTAATFRFDCAVSSWLYR
Mvan_6065|M.vanbaalenii_PYR-1 RHHRQLYRLAQLTSRDPDDAADALQDALLAAHRTARTFRHDSAVSSWLYR
Mflv_2200|M.gilvum_PYR-GCK QHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPG-TFEGWLHR
: * . . . * * *:: : . : : : **
MMAR_3051|M.marinum_M IARRVVADHIRHLQARPR----AAHGVDPELLLDRGRRARGFEDLVEVTT
MUL_2295|M.ulcerans_Agy99 IARRVVADHIRHLQARPR----AAHGVDPELLLDRGRRARGFEDLVEVTT
Mb2095|M.bovis_AF2122/97 IARHVVADHIRHVRSRPR----TTRGARPEHLIDGDRHARGFEDLVEVTT
Rv2069|M.tuberculosis_H37Rv IARHVVADHIRHVRSRPR----TTRGARPEHLIDGDRHARGFEDLVEVTT
MLBr_01448|M.leprae_Br4923 IARRVVADHIRRAQTRPR----TTFDGYPERMLNADRHARGFEDLVEVTT
MAV_2426|M.avium_104 IARRVVADHIRHLQSRPR----AAVGADPEHVLRTDRHARGFEDLVEVTT
MAB_3428c|M.abscessus_ATCC_199 IARRVVADHIRHLKSRPR----IAHGADLEEASLR-RPTHRFEELVELKS
TH_1729|M.thermoresistible__bu IARRVVVDQIRHNQSRPR----TSYAVDVHTVLDKRRPDGRFEDIVEIKL
MSMEG_6931|M.smegmatis_MC2_155 IVVNACLDRLRRTRTQPSATHYVELGHVNHLRDPAADPAPRVTTAITVER
Mvan_6065|M.vanbaalenii_PYR-1 IVVNACLDRLRRNRSR-------ACEELDDQAGPVVDPTGRVDTAIVVER
Mflv_2200|M.gilvum_PYR-GCK ITTNLFLDMVRRRGRIRMEALPEDYDRVPADEPNPEQIYHDSRLGADLQA
*. . * :*: :
MMAR_3051|M.marinum_M MIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRVARARDALLA
MUL_2295|M.ulcerans_Agy99 MIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTIRSRVARARDALLA
Mb2095|M.bovis_AF2122/97 MIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLA
Rv2069|M.tuberculosis_H37Rv MIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVARARDALLA
MLBr_01448|M.leprae_Br4923 MIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLA
MAV_2426|M.avium_104 MIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLA
MAB_3428c|M.abscessus_ATCC_199 LLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTIRSRVARARDELIG
TH_1729|M.thermoresistible__bu LLDGLDTDRRHALLLTQVLGLSYAEAAEVCGCAVGTIRSRVARARDDLLQ
MSMEG_6931|M.smegmatis_MC2_155 ALLQLPVDQRAAVVAVDMQGYSVAETARLLGVAEGTIKSRCARARAKLAR
Mvan_6065|M.vanbaalenii_PYR-1 ALMRLPLEQRAAVVAVDMQGYSIAETARMLGVAEGTVKSRCSRARTKLAA
Mflv_2200|M.gilvum_PYR-GCK ALDSLAPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
: * : * *:: :: * . : . * **::** *.* *
MMAR_3051|M.marinum_M DNERDD------LTG--------
MUL_2295|M.ulcerans_Agy99 DNERDD------LTG--------
Mb2095|M.bovis_AF2122/97 DAEPDD------LTG--------
Rv2069|M.tuberculosis_H37Rv DAEPDD------LTG--------
MLBr_01448|M.leprae_Br4923 DTEHNH------LTG--------
MAV_2426|M.avium_104 DGERND------LTG--------
MAB_3428c|M.abscessus_ATCC_199 WAEPEN------LTG--------
TH_1729|M.thermoresistible__bu QARPVD------RTG--------
MSMEG_6931|M.smegmatis_MC2_155 TLQYFDGDEPQPATSAHRGAAHP
Mvan_6065|M.vanbaalenii_PYR-1 SLDCFT------ATAE-------
Mflv_2200|M.gilvum_PYR-GCK HLARHSDVGAGRDTAKSA-----
*.