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MSYVFATPELVAAAATDLAGVQSVLSAANSAAAGPTMAVMAAGADEVSALIAGLFDAHAQAYQALSAQAL VFHDQFVQMLNAGASSYAAAEAANASPLQVVQNLGQNVLAAVNAPTQAVLGRPLIGDGANGSPNTGADGG AGGLLYGNGGNGGSGGLAQAGGNGGAAGLIGNGGSGGAGGADFAGTSGGMGGTGGWLWGNGGAGGGGGVG TTTTGGTGGAGGNAMGLFGNGGIGGAGGVGQNTTGTGGNGGAGGNAALLGFAGAGGVGGLGGATGGDGGQ GGNAALFGNGGDGGAGGAGANLDGGNGGLGGNAGLFGDGGHGGAGGVSFDPAGGDGGNGGQGGNATLFGY GGHGGAGGSSLNLAGGDGGDGGQGGFFGGGGAGGDGGAGYVLANAGAAGNGGDAGFFGNGGAGGSGQFGV GASSAGGIGGNGGRVIGDGGDGGVGGWGVLAAAGGKGGDAIGLFGQGGAGGTGGAAVGAGNHGGNGGDGG TGALIGNGGDGGAAGTSIGQSASGGNGGNARFLGNGGDGGPGIFGGTGGTGGQGGTLAGVPGAAGPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0299 | - | - | 100% (557) | PE-PGRS family protein, PE_PGRS1 |
| M. marinum M | MMAR_2645 | - | e-161 | 53.51% (641) | PE-PGRS family protein |
| M. marinum M | MMAR_3199 | - | e-160 | 54.59% (610) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | 1e-166 | 54.98% (613) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-94 | 44.21% (518) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1325c | PE_PGRS24 | 1e-166 | 54.81% (613) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 36.46% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-48 | 36.64% (453) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-21 | 40.86% (186) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-83 | 37.82% (624) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-39 | 39.38% (320) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 1e-160 | 55.28% (606) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 3e-95 | 43.13% (568) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0299|M.marinum_M ---------------------------------------MSYVFATP---
MUL_1145|M.ulcerans_Agy99 ---------------------------------------MSYVVASP---
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1360c|M.bovis_AF2122/97 ---------------------------------------MSFVIAAP---
Rv1325c|M.tuberculosis_H37Rv ---------------------------------------MSFVIAAP---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 --------------------------------------------------
MMAR_0299|M.marinum_M ----------------------------------------ELVAAAATDL
MUL_1145|M.ulcerans_Agy99 ----------------------------------------EYVAAAASDL
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1360c|M.bovis_AF2122/97 ----------------------------------------ETLVRAASDL
Rv1325c|M.tuberculosis_H37Rv ----------------------------------------ETLVRAASDL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 ---------------------------------------MNIVLGVSMAP
MMAR_0299|M.marinum_M AG----------------------VQSVLS--------------------
MUL_1145|M.ulcerans_Agy99 AG----------------------IGSALS--------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1360c|M.bovis_AF2122/97 AN----------------------IGSTLG--------------------
Rv1325c|M.tuberculosis_H37Rv AN----------------------IGSTLG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AN------------------------AGLS--------------------
MAV_4827|M.avium_104 SS------------------------------------------------
MMAR_0299|M.marinum_M --------AANSAAAGPTMAVMAAGADEVSALIAGLFDAHAQAYQALSAQ
MUL_1145|M.ulcerans_Agy99 --------TANAAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQALSEQ
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
Mb1360c|M.bovis_AF2122/97 --------AANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQ
Rv1325c|M.tuberculosis_H37Rv --------AANAAALGPTTELLAAGADEVSAAIASLFAAHGQAYQAVSAQ
MLBr_01183|M.leprae_Br4923 --------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQL
MAB_4284c|M.abscessus_ATCC_199 --------AVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNL
MAV_4827|M.avium_104 --------IQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAI
MMAR_0299|M.marinum_M ALVFHDQFVQMLNAGASSYAAAEAANASPLQVVQNLGQNVLAAVNAPTQA
MUL_1145|M.ulcerans_Agy99 ASAFHLQFVQAMTAGAGAYAGAEAVNASPLQAALDV-------LNAPAQA
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR-------------------
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGA-------VG--APG
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGA-------VG--APG
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAH-------VDGGTGG
Mb1360c|M.bovis_AF2122/97 MSAFHAQFVQTFTAGAGAYASAEAAAAAPLEGLLNI-------VNTPTQL
Rv1325c|M.tuberculosis_H37Rv MSAFHAQFVQTFTAGAGAYASAEAAAAAPLEGLLNI-------VNTPTQL
MLBr_01183|M.leprae_Br4923 TTEIAPPAADDVSILLAHFFSGHG--------------------------
MAB_4284c|M.abscessus_ATCC_199 QNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN-----PIASGNQ
MAV_4827|M.avium_104 LGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR-------RIDNVM
MMAR_0299|M.marinum_M VLGRPLIGDGANGSPNTGADGGAGGLLYGNGGNGGSGGLAQAGG------
MUL_1145|M.ulcerans_Agy99 LFGRPLIGDGAGGAP--GQSGGDGGLLYGNGGNGGNGGVGQAGG------
TH_3810|M.thermoresistible__bu ----TTDNNALDGGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG-------
Mflv_5091|M.gilvum_PYR-GCK VAGATGATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VAGATGATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGY
Mb1360c|M.bovis_AF2122/97 LLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGG------
Rv1325c|M.tuberculosis_H37Rv LLGRPLIGNGANGAPGTGQAGGAGGLLYGNGGAGGSGAPGQAGG------
MLBr_01183|M.leprae_Br4923 ---RQYQAHASQGAT--NHQDLIQSLLTSSSAYAGTETANHDSL------
MAB_4284c|M.abscessus_ATCC_199 VMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSG---
MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDG------
MMAR_0299|M.marinum_M --------NGGAAGLIGNGGSGGAGG---ADFAGTSGGMGGTG-------
MUL_1145|M.ulcerans_Agy99 --------AGGAAGLIGNGGSGGIGG---PGTTGLAGGAGGSG-------
TH_3810|M.thermoresistible__bu ---------VDVVGGNPDGGTPGAHG--ESHTPGVYTDR-----------
Mflv_5091|M.gilvum_PYR-GCK --------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1 --------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------
MSMEG_0868|M.smegmatis_MC2_155 VLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIG
Mb1360c|M.bovis_AF2122/97 --------PGGAAGLFGNGGAGGAGG--DGPGNGAAGGAGGAG-------
Rv1325c|M.tuberculosis_H37Rv --------PGGAAGLFGNGGAGGAGG--DGPGNGAAGGAGGAG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----PIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGG------
MAV_4827|M.avium_104 ------SIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG------
MMAR_0299|M.marinum_M -----------GWLWGNG------GAGGGGGVGTTT--------------
MUL_1145|M.ulcerans_Agy99 -----------GWLFGNG------GTGGRGGIGTTG--------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------AVGAAGAAG------TVGTAGATGGTG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------AIGTAGVAG------AAGTAGATGGTG--------------
MSMEG_0868|M.smegmatis_MC2_155 ANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGT
Mb1360c|M.bovis_AF2122/97 -----------GLLFGSG------GAGGPGGVGNTG--------------
Rv1325c|M.tuberculosis_H37Rv -----------GLLFGSG------GAGGPGGVGNTG--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------DYTNVSGHGSADIDKSVTVVDDHSQRN--------------
MAV_4827|M.avium_104 -----------LLLVGSG-----VDVAPLKQVLQTTTFLDVS--------
MMAR_0299|M.marinum_M -TGGTGGAGGNAMGLFGNGGIG----------------------------
MUL_1145|M.ulcerans_Agy99 -IGGIGGTGGDAVGLFGHGGTG----------------------------
TH_3810|M.thermoresistible__bu -QGEDGEDG-TGTGIGGRGGNG----------------------------
Mflv_5091|M.gilvum_PYR-GCK -TGANGGAG-GVGGVGGTGAAG--------------AAGGAGGLGETGTT
Mvan_1264|M.vanbaalenii_PYR-1 -VGGNGGAG-QAGGIGGTGAAG--------------AAGQAGTAGETGVT
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGHS-TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGT
Mb1360c|M.bovis_AF2122/97 -TGGLGGDG-GAAGLFGAGGIG----------------------------
Rv1325c|M.tuberculosis_H37Rv -TGGLGGDG-GAAGLFGAGGIG----------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTN---------------------------
MAV_4827|M.avium_104 -VAEEPETALARGAALAAANAP----------------------------
MMAR_0299|M.marinum_M -----------GAGGVG---------QNTTGTG----GNGGAGG------
MUL_1145|M.ulcerans_Agy99 -----------GTGGNGPDIFIAGGAGGSGGTGGLLFGNGGAGGGAPWGG
TH_3810|M.thermoresistible__bu --------------------------GSSSGTH----PMAEDG-------
Mflv_5091|M.gilvum_PYR-GCK GGAGGVGGQ--GTAGGTGGVGGIGGAGSTGAVG----GVGGKG----IQG
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGIGGQ--GTEGGTGGVGGVGGVGATGGAG----GVGGKG----IQG
MSMEG_0868|M.smegmatis_MC2_155 GGAGGMGEIYSGADGEATGISAGGDGGSATGAD----SLGGRGGTSWVQA
Mb1360c|M.bovis_AF2122/97 ---------------------GAGGPGFNGGAG----GAGGRS-------
Rv1325c|M.tuberculosis_H37Rv ---------------------GAGGPGFNGGAG----GAGGRS-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------TEIGSHNQANIGTSTSAG----GSAAVGG------
MAV_4827|M.avium_104 ---------------LFASSTAALAYAQDPGTG----AVDQYSLPDYLYV
MMAR_0299|M.marinum_M ----------------------------------------NAALLGFAGA
MUL_1145|M.ulcerans_Agy99 ADGGAGGDARLIGNGGGGGYEGSLGVLSGGTAGPGGDGGNAVGLIGNGGA
TH_3810|M.thermoresistible__bu ----------------------------------------EHVKALDGRP
Mflv_5091|M.gilvum_PYR-GCK GQG------------------------------------LQGGKGGDGGA
Mvan_1264|M.vanbaalenii_PYR-1 GQG------------------------------------LQGGQGGDGGT
MSMEG_0868|M.smegmatis_MC2_155 GYGP-----------------------TTGGKASGTAKAGHGGKASDGGK
Mb1360c|M.bovis_AF2122/97 ---------------------------------------GLFEVLAAGGA
Rv1325c|M.tuberculosis_H37Rv ---------------------------------------GLFEVLAAGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------NAGLAGNAGL
MAV_4827|M.avium_104 PVDP----------------------------------EPGDDELAYSAV
MMAR_0299|M.marinum_M GGVG---------------------------GLGGATGGDGGQGGN-AAL
MUL_1145|M.ulcerans_Agy99 GGAGA-------------------------AGLSGVTGGIGGNGGNGAQL
TH_3810|M.thermoresistible__bu GLDGG----------------------------NGSHGGNGGHGGR-GGF
Mflv_5091|M.gilvum_PYR-GCK GGKGGDADSMGS------------------AGATGGKGGNGGNGGR-GGL
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDATSMGE------------------AGATGGKGGNGGNGGR-GSL
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNI-AAI
Mb1360c|M.bovis_AF2122/97 GGTGG-------------------------LSVNGGTGGTGGTGGG-GGL
Rv1325c|M.tuberculosis_H37Rv GGTGG-------------------------LSVNGGTGGTGGTGGG-GGL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAG-------------------------LAGNAGLAGNAGLAGN-AGL
MAV_4827|M.avium_104 GEEDAESP--------------------TVVIEKLFLPEDSEPRRRPVLL
MMAR_0299|M.marinum_M FG----------------------------------------------NG
MUL_1145|M.ulcerans_Agy99 FG----------------------------------------------NG
TH_3810|M.thermoresistible__bu LG----------------------------------------------IG
Mflv_5091|M.gilvum_PYR-GCK FG---------------KGGNAGNGAD----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 FG---------------RGGNAGNGGN----------------------G
MSMEG_0868|M.smegmatis_MC2_155 HGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAG
Mb1360c|M.bovis_AF2122/97 FS----------------------------------------------NG
Rv1325c|M.tuberculosis_H37Rv FS----------------------------------------------NG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG----------------------------------------------NA
MAV_4827|M.avium_104 VG--------------------------------------------SGLA
MMAR_0299|M.marinum_M GDGGAGGAGANLD--GGNGGLGG---------------------------
MUL_1145|M.ulcerans_Agy99 GAGGAGGQSQLAS--GGTGGSGG---------------------------
TH_3810|M.thermoresistible__bu GSGGWGGHGGNGGDTDADGGNGG---------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGAGGAGGTGG-TGGAGGTGG-----------------TGGTGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GTGGNGGNGGTGG-TGGNGGTGG-----------------TGGTGGIGGA
MSMEG_0868|M.smegmatis_MC2_155 GNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGD
Mb1360c|M.bovis_AF2122/97 GAGGAGGFGVSGS-AGGNGGTGG---------------------------
Rv1325c|M.tuberculosis_H37Rv GAGGAGGFGVSGS-AGGNGGTGG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGN---------------------------
MAV_4827|M.avium_104 VVGISAVLALEIALAIGIRTTG----------------------------
MMAR_0299|M.marinum_M -----NAGLFGDGGHGGAGGVSFDPAGGDGGNGG---------------Q
MUL_1145|M.ulcerans_Agy99 -----MAALFGNGGAGGAAGVSLSGAPGTGGNGGSAQFMGDGDSGGLGDS
TH_3810|M.thermoresistible__bu ----------------------------DGGNGGSA--------GRGG-T
Mflv_5091|M.gilvum_PYR-GCK GSTGGTGGTGGTGGTGGTGGTG--GTGGTGGTGGTG--------GKGG-T
Mvan_1264|M.vanbaalenii_PYR-1 GSTGGTGGTGGTGGTGGTGGTG--GTGGTGGTGGTG--------GKGG-T
MSMEG_0868|M.smegmatis_MC2_155 GGTFVNAGANGNGGAGGAGGVSE-GEGGTGGHGGDG--------GRGG-D
Mb1360c|M.bovis_AF2122/97 ----DGGIFTGNGGTGGAGGTGT-GNQLVGGEGGAG--------GAGGNA
Rv1325c|M.tuberculosis_H37Rv ----DGGIFTGNGGTGGTGGTGT-GNQLVGGEGGAG--------GAGGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA--------GNAGLA
MAV_4827|M.avium_104 -----TVALQPTPNQHLIVPTEQAPAPPPVQASAPQ--------PKISVP
MMAR_0299|M.marinum_M GGNATLFGYG----------------------------------------
MUL_1145|M.ulcerans_Agy99 GGSAGAAGAGGLIGNPLDVVNAPTEALLGRPLIGDGADGAPGESGQDGGL
TH_3810|M.thermoresistible__bu GGLRGVFGIN----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGGAGGTG----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDGGTG----------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GALGGNGGTGGV--------------------------------------
Mb1360c|M.bovis_AF2122/97 GILFGAGGIG----------------------------------------
Rv1325c|M.tuberculosis_H37Rv GILFGAGGIG----------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG----------------------------------------
MAV_4827|M.avium_104 EPVAAPKPLS----------------------------------------
MMAR_0299|M.marinum_M --GHGGAGGSSLN-LAG---------GDGGDGGQGG--------------
MUL_1145|M.ulcerans_Agy99 LYGNGGNGGNGLSGQAGGAGGAAGLIGNGGNGGIGGPG------------
TH_3810|M.thermoresistible__bu -------------------------------GGNGRAG------------
Mflv_5091|M.gilvum_PYR-GCK --GDGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------D
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------D
MSMEG_0868|M.smegmatis_MC2_155 GLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGT
Mb1360c|M.bovis_AF2122/97 -----GTGGTGLGAPDP-----------GGTGGKGGVG------------
Rv1325c|M.tuberculosis_H37Rv -----GTGGTGLGAPDP-----------GGTGGKGGVG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----LAGNAGLAGNAG-------LAGNAAVAGNAAVAG-----------
MAV_4827|M.avium_104 -----PPVAAPLPAAPP----------PAAPPLPEAPP------------
MMAR_0299|M.marinum_M -----------------FFGGGGAGG-----------------DGGAGYV
MUL_1145|M.ulcerans_Agy99 ---TTGMSGGAGGAGGWLIGNGGHGG-----------------IGGLGIG
TH_3810|M.thermoresistible__bu -----------------LGGRGXXXX-----------------GGGVG--
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG----TGGQGGQGGQGG-----------------TGGTGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GLGGTGGTGG----TGGFGGQGGQGG-----------------TGGTGGQ
MSMEG_0868|M.smegmatis_MC2_155 ATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGN
Mb1360c|M.bovis_AF2122/97 ----------------GIGGAGALFG-----------------PGGAGGT
Rv1325c|M.tuberculosis_H37Rv ----------------GIGGAGALFG-----------------PGGAGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------NAAVAGNAAVGG---------------VLNTGVSGA
MAV_4827|M.avium_104 -----------------IPAAPPVVP--------------------VPVV
MMAR_0299|M.marinum_M LA------------------------------------------------
MUL_1145|M.ulcerans_Agy99 IG------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GG-LGGGGGTG-----------------------GQGGTGGTGGQGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GG-LGGVGGTG-----------------------GTGGTGGTGGQGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGG
Mb1360c|M.bovis_AF2122/97 GG------------------------------------------------
Rv1325c|M.tuberculosis_H37Rv GG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 IG------------------------------------------------
MAV_4827|M.avium_104 VP------------------------------------------------
MMAR_0299|M.marinum_M ----------------NAGAAGNGG--DAGFFGNGGAGGSGQF-------
MUL_1145|M.ulcerans_Agy99 ----------------DSGGAGGAGGAAIGLFGNGGTGGTGGYNQAFGAV
TH_3810|M.thermoresistible__bu -----------------AAVRSGNG-VFSGGGGTPSAGFGVPTTIQFPAG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG--------GTGGAGGDG-GLGGLGGFGGSGGTGGQGGLGGPG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG--------GTGGAGGDG-GLGGLGGFGGVGGTGGQGGQGGPG
MSMEG_0868|M.smegmatis_MC2_155 QGTIEANGPSAVASGIGAGGNGGDG-IDGGLGGNGGDGVVNTTANAANPG
Mb1360c|M.bovis_AF2122/97 -----------------FGASSADQ-MAGGIGGSGGSGGAAKLIGDGGAG
Rv1325c|M.tuberculosis_H37Rv -----------------FGASSADQ-MAGGIGGSGGSGGAAKLIGDGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------GSSHVGGAINESLGGSGSVGGSTAVGGGAHTG
MAV_4827|M.avium_104 ----------------PVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQ
MMAR_0299|M.marinum_M -GVG-----------------------ASSAG------------------
MUL_1145|M.ulcerans_Agy99 SGVGGAGGAGGQWYGNGGDGGTSWGGAAAGAGGDAGLIDNGGDGDSAGVL
TH_3810|M.thermoresistible__bu SCTSRAVSREGI--------------MPSSRAAS----------------
Mflv_5091|M.gilvum_PYR-GCK GSTGGAGGAGG----------------QAGTAGKGGLFG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GSTGGAGGAGG----------------QAGVAGKGGLFG-----------
MSMEG_0868|M.smegmatis_MC2_155 SATGTATGGDGG--------------KATGTASQGGNGGPS--------W
Mb1360c|M.bovis_AF2122/97 G-TGGDSVRGAA--------------GSGGTGGTGGLIG-----------
Rv1325c|M.tuberculosis_H37Rv G-TGGDSVRGAA--------------GSGGTGGTGGLIG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGVSTGVGVG--------------SHVGGGISESLGG-----------
MAV_4827|M.avium_104 PPVRVPQPPSPP---------------QVGGTVPQSPPQ-----------
MMAR_0299|M.marinum_M ---GIGGNG---GRVIGDGGDGG---------------------VGGWGV
MUL_1145|M.ulcerans_Agy99 RQNGIGGHGGAGGSLFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWAI
TH_3810|M.thermoresistible__bu ------ARAGAACASSTSRSRRSFCCSRA---------------------
Mflv_5091|M.gilvum_PYR-GCK -GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATG
Mvan_1264|M.vanbaalenii_PYR-1 -GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATG
MSMEG_0868|M.smegmatis_MC2_155 VQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATG
Mb1360c|M.bovis_AF2122/97 --DGGAGGAGGTGIEFGSVGGAGGAGGNAAGLSG-------AGGAGGAGG
Rv1325c|M.tuberculosis_H37Rv --DGGAGGAGGTGIEFGSVGGAGGAGGNAAGLSG-------AGGAGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --SGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG
MAV_4827|M.avium_104 -HQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSG--------GSGGGHVP
MMAR_0299|M.marinum_M L--------------------------------AAAGGKGGDAIGLFGQG
MUL_1145|M.ulcerans_Agy99 YNSFAGDDGSGGTAIGNGGDGGANIVSSGFILGAGGGGNGGNAVGLIGNG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAG--TNGA-NG
Mvan_1264|M.vanbaalenii_PYR-1 ASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAG--TNGA-NG
MSMEG_0868|M.smegmatis_MC2_155 NTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISG--HGGAGNG
Mb1360c|M.bovis_AF2122/97 FGETAGDGGAGGNAGLLNGDG-------------GAGGAGG--LGIAGDG
Rv1325c|M.tuberculosis_H37Rv FGETAGDGGAGGNAGLLNGDG-------------GAGGAGG--LGIAGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTGVGGGVNTGVG------------VGSHVGGGISESLGGSG
MAV_4827|M.avium_104 TPGAGGSGGSGGGHVPTPGTG-------------GPGGTGGSGGGHVPTP
MMAR_0299|M.marinum_M GAGGTGG----AAVG--AGNHG----------------------GNGGDG
MUL_1145|M.ulcerans_Agy99 GAGGTGADGFSTALGSDGGNGGT----------------GAWLLGNGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDG
Mb1360c|M.bovis_AF2122/97 GNGGKGGK--------AGMVG------------------------NGGDG
Rv1325c|M.tuberculosis_H37Rv GNGGKGGK--------AGMVG------------------------NGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVGGGAHTSAINDALG-------------------------GSG
MAV_4827|M.avium_104 GAGTPGGSGGGHLPFPGAGSTP---------------------------G
MMAR_0299|M.marinum_M GTG------------------ALIGNGGDGGAAGTSIG----QSASGGNG
MUL_1145|M.ulcerans_Agy99 GSGGSTAGVHPAGDGGNSGMSALIGNGGAGGSAGVSPTGV--FPSNGGSG
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGG---------------AGGEGGEGGDGGKGGAGAE--------GGAG
Mvan_1264|M.vanbaalenii_PYR-1 GAGG---------------AGGEGGEGGAGGAGGDGSE--------GGAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNTS----VWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAG
Mb1360c|M.bovis_AF2122/97 GAGG----------------ASVVANGGVGGSGGNATL--------IGNG
Rv1325c|M.tuberculosis_H37Rv GAGG----------------ASVVANGGVGGSGGNATL--------IGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SVGG-----------------STAVGGGAHTSAINESMNSSINASHSSSM
MAV_4827|M.avium_104 GSGG-----------------GHLPTPGAGTPGGGLGG-------FGGGH
MMAR_0299|M.marinum_M GNARFLGNGGDGGP-GIFGGTGGTGGQGGTLAGVPGAAGPS--
MUL_1145|M.ulcerans_Agy99 GNAQLIGDGGDGGR-GDSGGTGGAGGTGGSLAGHDGSDGD---
TH_3810|M.thermoresistible__bu -------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGGGAGGSGAGGAG--GAGGSGGSGGSGG-SGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GSGGAGGSGTGGAG--GAGGSGGSGGSGG-AGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GNGGTGGTTAGGSGNGGNGGNGGNGGADG-TPGTAGTTGANNP
Mb1360c|M.bovis_AF2122/97 GNGGNGGVGS-------APGKGGAGGTAG-LLGLNGSPGLS--
Rv1325c|M.tuberculosis_H37Rv GNGGNGGVGS-------APGKGGAGGTAG-LLGLNGSPGLS--
MLBr_01183|M.leprae_Br4923 -------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-
MAV_4827|M.avium_104 APAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-