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MSFLVTAPEILAAAATDLDGIGAAIGAANAAAAAPTTAVLAAGADEISAAMASLFTAHAQAYQGLSVQVG AFHNQFVQALTGAGGAYAAAEAANVSPLQAAAQDMLTAIRAPAQALLGRPLIGNGADGAPGQAGGDGGLL YGNGGNGGTSTTAGVAGGAGGSAGLIGNGGAGGGGGAGAVGGNGGAGGWLFGNGGAGGAGGATPGIGGGG GAGGAGGIGGAAGLFGNGGAGGVGGDGGLNYYGDGGVAGAGGDGGRGGWLHGDGGDGGAGGDGGRGLPGG DGGSGGAGGGTGLWGSGGAGGQGGTGGTGLNGNAPFADGQHPVILDGGHGGTGGNGGAAGNGGLLFGNGG NGGLGGMGGGGGNGLPSTGVGGDGGDGGNGGTAGNGGWLIGNGGTGGQGGAGFAGGTGADNVSAGRPGGA GGTGGIGAGGGNAGLIGTGGSGGNGGMGGHGGDSGYGDQTGGQGGNGGMGGAGGAAGNGGLLLGSGSRGG DGGDGGNGGEGRGGFSVPQHGVGGQGGTGGNGSDGGWLYGDGGAGGAGGNGGFGGSGVQNGAGGDAGSGG DSRLIGDGGAAGAGGTGAPPGADGHSGADGLLSAALGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4224 | - | - | 100% (598) | PE-PGRS family protein |
| M. marinum M | MMAR_4223 | - | 0.0 | 64.65% (611) | PE-PGRS family protein |
| M. marinum M | MMAR_5321 | - | e-173 | 50.28% (724) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 0.0 | 57.03% (661) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-115 | 44.59% (601) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 0.0 | 56.93% (664) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-13 | 40.22% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 8e-45 | 36.46% (395) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-22 | 43.53% (170) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-95 | 39.44% (682) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-45 | 37.61% (351) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3292 | - | 1e-170 | 54.60% (630) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-114 | 45.32% (587) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4224|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 --------------------------------------------------
Rv1091|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4224|M.marinum_M --------------------------------------------------
MUL_3292|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 ---------------------------------------MSFVIAAP---
Rv1091|M.tuberculosis_H37Rv ---------------------------------------MSFVIAAP---
MMAR_4224|M.marinum_M ---------------------------------------MSFLVTAP---
MUL_3292|M.ulcerans_Agy99 ---------------------------------------MSYVIAAP---
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MLBr_01183|M.leprae_Br4923 ---------------------------------------MPLFLNAEP--
MAV_4827|M.avium_104 ---------------------------------------MNIVLGVS---
Mb1121|M.bovis_AF2122/97 ----------------------------------------EALVAVASDL
Rv1091|M.tuberculosis_H37Rv ----------------------------------------EALVAVASDL
MMAR_4224|M.marinum_M ----------------------------------------EILAAAATDL
MUL_3292|M.ulcerans_Agy99 ----------------------------------------EMLAGAATDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MAV_4827|M.avium_104 ---------------------------------------MAPSSIQMVVL
Mb1121|M.bovis_AF2122/97 AG---------------------------------------IGSALAEAN
Rv1091|M.tuberculosis_H37Rv AG---------------------------------------IGSALAEAN
MMAR_4224|M.marinum_M DG---------------------------------------IGAAIGAAN
MUL_3292|M.ulcerans_Agy99 AG---------------------------------------IGAALQSAN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MLBr_01183|M.leprae_Br4923 EG---------------------------------------LSAATVASN
MAV_4827|M.avium_104 EG----------------------------------------EYADGATV
Mb1121|M.bovis_AF2122/97 AAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQA
Rv1091|M.tuberculosis_H37Rv AAALAPTTALLAAGADEVSAAIAALFGAHGQAYQTVSAQASAFHAQFVQA
MMAR_4224|M.marinum_M AAAAAPTTAVLAAGADEISAAMASLFTAHAQAYQGLSVQVGAFHNQFVQA
MUL_3292|M.ulcerans_Agy99 GAAAAPITGVLAAGADEISAAVAALFSGHALDYQALSTQMAGFHQQFVTA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MLBr_01183|M.leprae_Br4923 AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS
MAV_4827|M.avium_104 EEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQ
Mb1121|M.bovis_AF2122/97 LTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQA--LLGRPLIGDGAN
Rv1091|M.tuberculosis_H37Rv LTGGGGAYAAAEAANVSAAQSTDQRLLDLINGPTQA--LLGRPLIGDGAN
MMAR_4224|M.marinum_M LTGAGGAYAAAEAANVSPLQAAAQDMLTAIRAPAQA--LLGRPLIGNGAD
MUL_3292|M.ulcerans_Agy99 LNSAGASYAAAEAASANPLQAVEQQLLGVINAPTQA--LLGRPLIGDGTA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MLBr_01183|M.leprae_Br4923 LLTSSSAYAGTETANHDSL-------------------------------
MAV_4827|M.avium_104 LEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGG--AMGYERTAVLLV
Mb1121|M.bovis_AF2122/97 GGPGQDGGPGGLLYGNGGNG--GTSTTAGVAGGNG---------------
Rv1091|M.tuberculosis_H37Rv GGPGQDGGPGGLLYGNGGNG--GTSTTAGVAGGNG---------------
MMAR_4224|M.marinum_M GAPGQAGGDGGLLYGNGGNG--GTSTTAGVAGGAG---------------
MUL_3292|M.ulcerans_Agy99 GAPGQNGGDGGLLWGNGGAG--GVGTAAHPTGGSG---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAG---------------
Mb1121|M.bovis_AF2122/97 -GAAGLIGNGGAGGG-----------------------------------
Rv1091|M.tuberculosis_H37Rv -GAAGLIGNGGAGGG-----------------------------------
MMAR_4224|M.marinum_M -GSAGLIGNGGAGGG-----------------------------------
MUL_3292|M.ulcerans_Agy99 -GSAGLIGTGGAGGAGY---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 QLSAMVAGLEKLESLP----------------------------------
Mb1121|M.bovis_AF2122/97 -------------------------------------------GGAGAAG
Rv1091|M.tuberculosis_H37Rv -------------------------------------------GGAGAAG
MMAR_4224|M.marinum_M -------------------------------------------GGAGAVG
MUL_3292|M.ulcerans_Agy99 -------------------------------------------GPAAQTG
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------ADHGSNVGVD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------------------------GGLLLVG
Mb1121|M.bovis_AF2122/97 GNGGAGGWLY----------------GNGGAGGAGGTSVIPGVAGGNGGA
Rv1091|M.tuberculosis_H37Rv GNGGAGGWLY----------------GNGGAGGAGGTSVIPGVAGGNGGA
MMAR_4224|M.marinum_M GNGGAGGWLF----------------GNGGAGGAGG--ATPGIGGG----
MUL_3292|M.ulcerans_Agy99 ATGGSG--------------------GVGGTGGSGLDGPDSGAAGG----
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SGVDVAPLKQVLQ-------------TTTFLDVSVAEEPETALARG----
Mb1121|M.bovis_AF2122/97 GGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAG---
Rv1091|M.tuberculosis_H37Rv GGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAG---
MMAR_4224|M.marinum_M ---------------------------GGAGGAGGIGGAAGLFGNGG---
MUL_3292|M.ulcerans_Agy99 -----------------------------AGGSGGSGGAARLFGNGG---
Mflv_5091|M.gilvum_PYR-GCK ------------------GTAGGTGGVGGIGGAGSTGAVGGVGGKG----
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTEGGTGGVGGVGGVGATGGAGGVGGKG----
MSMEG_0868|M.smegmatis_MC2_155 -----------------SGADGEATGISAGGDGGSATGADSLGGRGGTSW
TH_3810|M.thermoresistible__bu --------------------------VDVVGGNP----------------
MAB_4284c|M.abscessus_ATCC_199 -----------------TTNINDSFNTDRSTNIGSGNTTNTEIGSHN---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------------------AALAAANAPLFASSTAALAYAQ---
Mb1121|M.bovis_AF2122/97 -----------------------AGGNGGKGGAGGAAFSINF--------
Rv1091|M.tuberculosis_H37Rv -----------------------AGGNGGKGGAGGAAFSINF--------
MMAR_4224|M.marinum_M -----------------------AGGVGGDGGLN----------------
MUL_3292|M.ulcerans_Agy99 -----------------------AGGSGGKGGNGG---------------
Mflv_5091|M.gilvum_PYR-GCK IQGGQG-------------LQGGKGGDGGAGGKGGDADSMGS--------
Mvan_1264|M.vanbaalenii_PYR-1 IQGGQG-------------LQGGQGGDGGTGGTGGDATSMGE--------
MSMEG_0868|M.smegmatis_MC2_155 VQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATG
TH_3810|M.thermoresistible__bu --------------------------DGGTPG------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------QANIGTS-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 ----------TAGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGGS
Rv1091|M.tuberculosis_H37Rv ----------TAGDGGAGGAGGSGGHALLWGAGGAGGNGGSGGTGGAGGS
MMAR_4224|M.marinum_M ----------YYGDGGVAGAGGDG--------------------------
MUL_3292|M.ulcerans_Agy99 ----------SAIETGNDGAAGAG--------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AGATGGKGGNGGNGGRGGLFG---------------KGGN
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGATGGKGGNGGNGGRGSLFG---------------RGGN
MSMEG_0868|M.smegmatis_MC2_155 NTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGN
TH_3810|M.thermoresistible__bu ------------AHGESHTPGVYTDRQ-----------------------
MAB_4284c|M.abscessus_ATCC_199 -----------TSAGGSAAVGGNAGLAGNAG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------DPGTGAVDQYSLPDYLYVP------------------
Mb1121|M.bovis_AF2122/97 TAGAGG------------------------NGGAGGGGGTGGLLFGNGGA
Rv1091|M.tuberculosis_H37Rv TAGAGG------------------------NGGAGGGGGTGGLLFGNGGA
MMAR_4224|M.marinum_M --------------------------------------GRGGWLHGDGGD
MUL_3292|M.ulcerans_Agy99 --------------------------------------GHGGWLVGNGGI
Mflv_5091|M.gilvum_PYR-GCK AGNGAD----------------------GGTGGAGGAGGTGG-TGGAGGT
Mvan_1264|M.vanbaalenii_PYR-1 AGNGGN----------------------GGTGGNGGNGGTGG-TGGNGGT
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGD
TH_3810|M.thermoresistible__bu --------------------------------GEDGEDGTGTGIGGRGGN
MAB_4284c|M.abscessus_ATCC_199 ------------------------------LAGNAGLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------------VDPEPGDDELAYSAVGE
Mb1121|M.bovis_AF2122/97 GGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVG
Rv1091|M.tuberculosis_H37Rv GGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGGAGGNARLWGVG
MMAR_4224|M.marinum_M G-------------------GAGGDGGRGLPGGDGGSGGAGGGTGLWGSG
MUL_3292|M.ulcerans_Agy99 GGDG----------------GSGGVGGDAGAYGPPANGGAGGHGGMGGVG
Mflv_5091|M.gilvum_PYR-GCK GG-------------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GG-------------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GAGASVWKAN--GQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG
TH_3810|M.thermoresistible__bu GG------------------SSSGTHPMAEDG--------EHVKALDGRP
MAB_4284c|M.abscessus_ATCC_199 GN-----------------AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ED------------------AESPTVVIEKLFLPEDSEPRRRPVLLVGSG
Mb1121|M.bovis_AF2122/97 GAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEGGAAG
Rv1091|M.tuberculosis_H37Rv GAGGAGGDGGAGGAGGKGGSGLSGNANGGAGGDSGRGGTGGAGGEGGAAG
MMAR_4224|M.marinum_M GAG---------GQGGTGGTGLNGNAPFADGQHP----------------
MUL_3292|M.ulcerans_Agy99 GDAG-----LLFGSGGAGGVGGNG-AIGGTGVMS----------------
Mflv_5091|M.gilvum_PYR-GCK GTG---GTGGTGGTGGTGGKGGTGGTGGAGGTG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GTG---GTGGTGGTGGTGGKGGTGGTGGDGGTG-----------------
MSMEG_0868|M.smegmatis_MC2_155 GVSE--GEGGTGGHGGDGGRGGDGALGGNGGTGGV-------------GL
TH_3810|M.thermoresistible__bu GLD-----GGNGSHGGNGGHGGRGGFLGIGGSG-----------------
MAB_4284c|M.abscessus_ATCC_199 GLA------GNAGLAGNAGLAGNAGLAGNAGLAG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVP-----------
Mb1121|M.bovis_AF2122/97 LLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGGSGGD
Rv1091|M.tuberculosis_H37Rv LLVGTGGHGGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGGSGGD
MMAR_4224|M.marinum_M -VILDGGHGGTGGNG-----------------------------------
MUL_3292|M.ulcerans_Agy99 ---GAGGAGGDGGNG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GDGGTGGTGGTGGTG-----------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTGGTG-----------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GNGGKGGNGGNGGNGGTY--------------------------------
TH_3810|M.thermoresistible__bu ---GWGGHGGNGGD------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -NAGLAGNAGLAGNAG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -TEQAPAPPPVQASAP----------------------------------
Mb1121|M.bovis_AF2122/97 GGGGAAGPAGWLFGDGGAGGNGGAAA------------AGGAGGQAG---
Rv1091|M.tuberculosis_H37Rv GGGGAAGPAGWLFGDGGAGGNGGAAA------------AGGAGGQAG---
MMAR_4224|M.marinum_M ---GAAGNGGLLFGNGGNGGLGGMGG------------GGGNGLPST---
MUL_3292|M.ulcerans_Agy99 -------GYAQLIGDGGGGGAGGAG-------------YSASGLPPA---
Mflv_5091|M.gilvum_PYR-GCK -------------GTGGTGGTGGAG-----------DGTGGTGGTGG---
Mvan_1264|M.vanbaalenii_PYR-1 -------------GTGGTGGTGGAG-----------DGLGGTGGTGG---
MSMEG_0868|M.smegmatis_MC2_155 -------VDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGD
TH_3810|M.thermoresistible__bu --------------TDADGGNGGDG---------------GNGGSAG---
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAG-------------LAGNAGLAG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------QPKISVPEPVAAPKPLSP------------PVAAPLPAAP--
Mb1121|M.bovis_AF2122/97 -----------------------------GGGGNGGNGGNGGNGGNGGNG
Rv1091|M.tuberculosis_H37Rv -----------------------------GGGGNGGNGGNGGNGGNGGNG
MMAR_4224|M.marinum_M -----------------------------GVGGDGGDGGNGGTAGNGG--
MUL_3292|M.ulcerans_Agy99 -----------------------------GIGAPGGAGGAGGSGG-----
Mflv_5091|M.gilvum_PYR-GCK -TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG--
Mvan_1264|M.vanbaalenii_PYR-1 -TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG--
MSMEG_0868|M.smegmatis_MC2_155 ADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGA
TH_3810|M.thermoresistible__bu ------------------------------RGGTGGLRGVFGINGGNG--
MAB_4284c|M.abscessus_ATCC_199 ------------------------------NAAVAGNAAVAGNAAVAG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------PPAAPPLPEAPPIPAAPPVVP
Mb1121|M.bovis_AF2122/97 AT--------------GGWLYGNGGAGGQGATAGAGGAGANGVSSTNGG-
Rv1091|M.tuberculosis_H37Rv AT--------------GGWLYGNGGAGGQGATAGAGGAGANGVSSTNGGG
MMAR_4224|M.marinum_M ------------------WLIGNGGTGGQGGAGFAGGTGADNVSAGRPG-
MUL_3292|M.ulcerans_Agy99 ------------------WLVGNGGAGGIGGIGASGSFGAP---------
Mflv_5091|M.gilvum_PYR-GCK ---------------------GQGGTGGTGGQGGTGGTGGTGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------GTGGTGGTGGQGGTGGTGGTGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 ATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVA
TH_3810|M.thermoresistible__bu ----------------------RAGLGGRGXXXXGGGVGAAVRSG-----
MAB_4284c|M.abscessus_ATCC_199 ----------------------NAAVGGVLNTGVSGAIGGSSHVG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VP----------------VVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLS
Mb1121|M.bovis_AF2122/97 ---GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFI
Rv1091|M.tuberculosis_H37Rv TG-GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGASGGAGDRGGAGGTGFI
MMAR_4224|M.marinum_M ------GAGGTGGIGAGGGNAGLIGTGGSGGNGGMGGHG-----GDSGYG
MUL_3292|M.ulcerans_Agy99 --------SGQGGNGGIGGAAGLFGQGGAGGNGGQGGGDDFALSGGAGGA
Mflv_5091|M.gilvum_PYR-GCK ---GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--Q
Mvan_1264|M.vanbaalenii_PYR-1 ---GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--Q
MSMEG_0868|M.smegmatis_MC2_155 SGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKA
TH_3810|M.thermoresistible__bu ----------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG---
MAB_4284c|M.abscessus_ATCC_199 ----GAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG---
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYG
Mb1121|M.bovis_AF2122/97 SSDGGAG-----------GDGGDGGNGGAGGTGGLLFG--AGGNGGPG--
Rv1091|M.tuberculosis_H37Rv SSDGGAG-----------GDGGDGGNGGAGGTGGLLFG--AGGNGGPG--
MMAR_4224|M.marinum_M DQTGGQG-----------GNGGMGGAGGAAGNGGLLLG--SGSRGGDG--
MUL_3292|M.ulcerans_Agy99 GGAGGHGGQLY-------GDGGGGGAGGMGGSVDIAESGVTGGRGGSG--
Mflv_5091|M.gilvum_PYR-GCK AGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG--
Mvan_1264|M.vanbaalenii_PYR-1 AGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG--
MSMEG_0868|M.smegmatis_MC2_155 TGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGN
TH_3810|M.thermoresistible__bu ---------------------IMPSSRAASARAG----------------
MAB_4284c|M.abscessus_ATCC_199 -----------------GISESLGGSGSVGGSTAVGGGAHTGVGGGVS--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GG----------------HVPTPGAGGSGGSGGGHVPTPGAGGSGGSG--
Mb1121|M.bovis_AF2122/97 -----------GSGGAADIGGNGGAGNGGGTDGNGGNGGSGGGAGSGGDG
Rv1091|M.tuberculosis_H37Rv -----------GSGGAADIGGNGGAGNGGGTDGNGGNGGSGGGAGSGGDG
MMAR_4224|M.marinum_M -----------GDG------GNGGEGRGG---------------------
MUL_3292|M.ulcerans_Agy99 -----------SVGGGAGLWGAGGQGGDGAQGGDGG--------------
Mflv_5091|M.gilvum_PYR-GCK ----AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGA
Mvan_1264|M.vanbaalenii_PYR-1 ----AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGA
MSMEG_0868|M.smegmatis_MC2_155 ALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDS
TH_3810|M.thermoresistible__bu -----------AACASSTSRSRRSFCCSRA--------------------
MAB_4284c|M.abscessus_ATCC_199 --------TGVGVGSHVGGGISESLGGSGSVGGSTAVG---------GGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -------------GGHVPTPGTGGPGGTGGSGGGHVP-------------
Mb1121|M.bovis_AF2122/97 GGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGG----
Rv1091|M.tuberculosis_H37Rv GGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGGSFGLPGLNGSGG----
MMAR_4224|M.marinum_M -----------------------------------FSVP-QHGVGG----
MUL_3292|M.ulcerans_Agy99 -----------------------------------AGVDTTTGAGG----
Mflv_5091|M.gilvum_PYR-GCK QGSAG-------------TNGA-NGANGSQGAAGKAGATGTTGATG----
Mvan_1264|M.vanbaalenii_PYR-1 QGSAG-------------TNGA-NGANGSQGAAGKAGATGTTGATG----
MSMEG_0868|M.smegmatis_MC2_155 TAISG-------------HGGAGNGGNGGKGADGWVQAYDPAGPVGSKIA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HTGVG-------------GGVNTGVGVGSHVGGGISESLGGSGSVG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1121|M.bovis_AF2122/97 ----DGGDGGNGAPGGVLYGNGGAGGQGS-----------SGGIGGPGAT
Rv1091|M.tuberculosis_H37Rv ----DGGDGGNGAPGGVLYGNGGAGGQGS-----------SGGIGGPGAT
MMAR_4224|M.marinum_M ----QGGTGGNGSDGGWLYGDGGAGGAGG-----------NGGFGGSGVQ
MUL_3292|M.ulcerans_Agy99 ----DGGAGAGGGTSGFLYGNGGAGGAGG-----------HGG-GGPGMG
Mflv_5091|M.gilvum_PYR-GCK ----AAGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGD
Mvan_1264|M.vanbaalenii_PYR-1 ----AAGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGA
MSMEG_0868|M.smegmatis_MC2_155 NSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---GSTAVGGGAHTSAINDALGGSGSVGG----------STAVGGGAHTS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----TPGAGTPGGSGGGHLPFPGAGSTPG------------GSGGGHLPT
Mb1121|M.bovis_AF2122/97 GGAGGKGGD----GGDAQLIGDGGNGGNGGAGGTG--GTPGPGGPGGSGG
Rv1091|M.tuberculosis_H37Rv GGAGGKGGD----GGDAQLIGDGGNGGNGGAGGTG--GTPGPGGPGGSGG
MMAR_4224|M.marinum_M NGAGGDAGS----GGDSRLIGDGGAAG---AGGTG--APPGADGHSGADG
MUL_3292|M.ulcerans_Agy99 -GDGGDGGD----GGRAQLIGTGGNGG---AGGTA--APGGTDGTAGAAG
Mflv_5091|M.gilvum_PYR-GCK GGKGGAGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGDGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGAGTPGGGLGGFGGGHAPAPGGGLGGGGGHAPAPGGGLGGFGGGHSGGG
Mb1121|M.bovis_AF2122/97 LGGLLFGQTGTAGVSP
Rv1091|M.tuberculosis_H37Rv LGGLLFGQTGTAGVSP
MMAR_4224|M.marinum_M LLSAALGA--------
MUL_3292|M.ulcerans_Agy99 KGGVLFGTDGATG---
Mflv_5091|M.gilvum_PYR-GCK SGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 AGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 TPGTAGTTGANNP---
TH_3810|M.thermoresistible__bu ----------------
MAB_4284c|M.abscessus_ATCC_199 HTTLPGAEHH------
MLBr_01183|M.leprae_Br4923 ----------------
MAV_4827|M.avium_104 LGGLGGGHK-------