For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ERLSGLDAGMLYSESPTVPLHVCSVTELDTSTVPGGYTFAKFRDHLASRVPAIPEFRTKLADNDLNFDHP VWVEDDDFDLTRHLNRVALPEPGGRDELAELCGRLIGMPLERSKPLWEMWVIEGVGGSAAREDGRLALLL KVHHAAVDGVSAADLLAKLLDTEPDAPPPDPVDAPTGASTWEIAADGLWRVATRPWQLTRVVPVATSLVT NTVSRALSGTAMALPFSAPSTPFNAPLTSDRNIAFAQLDLDDVKKVKNQAEVKVNDVVMALCAGALRGYL DERGALPDKPLIAVVPSSVHGQTDRPGRNQLSGMFCNLHTDIEDPLDRLYAIGASNVRAKEHSGSLGPSM LMDLAQSVSRTMFGWLLGGLSRTSLGNTAIHNVIISNVAGPPTTLYSGGAEITGLYPLGPIFPGSGLNIT VMSMGDKLNVGIISCPKLTDDLWDLADRFDAELADLLARS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5212 | - | - | 100% (461) | hypothetical protein Mflv_5212 |
| M. gilvum PYR-GCK | Mflv_0349 | - | 1e-80 | 38.38% (469) | hypothetical protein Mflv_0349 |
| M. gilvum PYR-GCK | Mflv_2428 | - | 4e-65 | 33.84% (458) | hypothetical protein Mflv_2428 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1791 | - | 1e-123 | 53.53% (411) | hypothetical protein Mb1791 |
| M. tuberculosis H37Rv | Rv1760 | - | 1e-138 | 53.49% (458) | hypothetical protein Rv1760 |
| M. leprae Br4923 | MLBr_01244 | - | 8e-29 | 26.27% (434) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_1917 | - | 1e-142 | 52.81% (462) | hypothetical protein MAB_1917 |
| M. marinum M | MMAR_3298 | - | 1e-151 | 55.63% (462) | hypothetical protein MMAR_3298 |
| M. avium 104 | MAV_2240 | - | 1e-151 | 56.74% (460) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_4297 | - | 1e-155 | 58.82% (459) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2477 | - | 1e-151 | 57.52% (459) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_1818 | - | 3e-75 | 37.87% (470) | hypothetical protein MUL_1818 |
| M. vanbaalenii PYR-1 | Mvan_1065 | - | 0.0 | 71.83% (458) | hypothetical protein Mvan_1065 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5212|M.gilvum_PYR-GCK ----------------------------------MERLSGLDAG--MLYS
Mvan_1065|M.vanbaalenii_PYR-1 ----------------------------------MERLSGLDAG--LLYS
MMAR_3298|M.marinum_M ----------------------------------MQRLSGLDAS--FLYL
MAV_2240|M.avium_104 -------------------------------MLRMQRLSGLDAS--FLYL
MSMEG_4297|M.smegmatis_MC2_155 ----------------------------------MQRLSGLDAS--FLYL
TH_2477|M.thermoresistible__bu --------------------------VPPPYDRGMQRLSGLDAS--FLYL
MAB_1917|M.abscessus_ATCC_1997 ----------------------------------MQRLSGLDAS--FLYL
Mb1791|M.bovis_AF2122/97 MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAF--FLYM
Rv1760|M.tuberculosis_H37Rv MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAF--FLYM
MUL_1818|M.ulcerans_Agy99 ----------------------------------MRRLSSVDAA--FWSA
MLBr_01244|M.leprae_Br4923 ------------------------------MADSVEGIGPFDELGALDYL
:. :. .* :
Mflv_5212|M.gilvum_PYR-GCK ESPTVPLHVCSVTELDTSTVPGGYTFAKFRDHLASRVPAIPEFRTKLADN
Mvan_1065|M.vanbaalenii_PYR-1 ESATVPLHVCSVVELDTSTVPGGYSFERFRDELAKRIPALPEFRAKLADS
MMAR_3298|M.marinum_M ETSNQPMHVCSIMELDTSTMPGGYTFDRLQDALALRIKAMPEFREKLANS
MAV_2240|M.avium_104 ETSSQPMHVCSIIELDTSTVPGGYTFERLRDALVRRIRAVPPFREKLADS
MSMEG_4297|M.smegmatis_MC2_155 ETAAQPMHVCSVLELDTSTMPGGYTFDRLRDALSLRIKAMPEFREKLADS
TH_2477|M.thermoresistible__bu ETPDQPLHVCSILELDTSTIPGGYDFHQLREALLLRIKAMPEFREKLADN
MAB_1917|M.abscessus_ATCC_1997 ETPTQPMHVCGVLELDTTTIPGGYSFEKLRTKLAERVEGIPSFREKLADS
Mb1791|M.bovis_AF2122/97 ETPSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADT
Rv1760|M.tuberculosis_H37Rv ETPSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADT
MUL_1818|M.ulcerans_Agy99 ETAGWHMHVGALAICDPTDAP-DYSFQRLRELLIERLPEIPQLRWRVTGA
MLBr_01244|M.leprae_Br4923 LHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRVLRLRQKVVVP
: ::: : :* ::.
Mflv_5212|M.gilvum_PYR-GCK DLNFDHPVWVEDDDFDLTRHLNRVALPEPGGRDELAELCGRLIGMPLERS
Mvan_1065|M.vanbaalenii_PYR-1 QLNLDHPVWVEDKDFDLARHLNRIALPAPGGREELAEVCGHIASTLLDRT
MMAR_3298|M.marinum_M ALNLDHPVWVDDEDFQLHRHLHRIGLPPPGGRAELSQICGHIASLPLDRS
MAV_2240|M.avium_104 PLNLDHPVWVDDEDFDVDRHLHRIAVPAPGGRAELSQICGHIAQTPLDRR
MSMEG_4297|M.smegmatis_MC2_155 RFNLDHPVWVEDNDFDVDRHLHRIGLPGPGGRAELAEICGHIASLPLDRS
TH_2477|M.thermoresistible__bu RFNLDHPVWVEDADFDVDRHLHRIGLPAPGGPAELAEICGHLAALPLDRS
MAB_1917|M.abscessus_ATCC_1997 RLNLDHPVWVDDDDFDIDRHLHHVGLPAPGGKAEIADMCGHIASLPLDRA
Mb1791|M.bovis_AF2122/97 ELNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRD
Rv1760|M.tuberculosis_H37Rv ELNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRD
MUL_1818|M.ulcerans_Agy99 PLGLDRPWFVEDQDLDVDFHVRRIGVPAPGGRRELEELVGRLMSYKLDRS
MLBr_01244|M.leprae_Br4923 TLPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVS
: * :* * :::: *:.:: :* ** *: :: : ::
Mflv_5212|M.gilvum_PYR-GCK KPLWEMWVIEGVGGSAAREDGRLALLLKVHHAAVDGVSAADLLAKLLDTE
Mvan_1065|M.vanbaalenii_PYR-1 KPLWEMWVIEGC----AKAD-TLALMIKVHHAAVDGVSAAHLLHQLCDEV
MMAR_3298|M.marinum_M RPLWEMWVIEGVAGTDCHHDGRLAVLTKVHHAAVDGVTGANLMSQLCTTE
MAV_2240|M.avium_104 RPLWEMWVIEGVAGTDCHRDGRLAVMTKVHHAGVDGVTGANLMSQLCATE
MSMEG_4297|M.smegmatis_MC2_155 RPLWEMWVIENVAGTDAHAGGRLALMTKVHHASVDGVTGANLLSQLCTTE
TH_2477|M.thermoresistible__bu RPLWEMWVIENIDGTDPRSGGPLVVLTKVHHAAVDGVTGANLLSQVCTTE
MAB_1917|M.abscessus_ATCC_1997 RPLWEMWVIETGDTN------RLVVMTKMHHASVDGVTGANLMSALCGLE
Mb1791|M.bovis_AF2122/97 RPLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQ
Rv1760|M.tuberculosis_H37Rv RPLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQ
MUL_1818|M.ulcerans_Agy99 RPLWELWVIEGVEGG------RIATLTKMHHAIVDGVSGAGLGEILLDVT
MLBr_01244|M.leprae_Br4923 RPLWTATLVEGLAAG------RAAMLLQISHAITDGVGSVEMFAEMYDLE
:*** ::* . : :: ** .*** .. : :
Mflv_5212|M.gilvum_PYR-GCK PDAPPP--DPVDAPTGASTWEIAADGLWRVATR------------PWQLT
Mvan_1065|M.vanbaalenii_PYR-1 PDAPPP--EPVEGPGDATRLRIAADGLWRFVTL------------PWQLT
MMAR_3298|M.marinum_M ADAPAP--DPVDGVGGATDWQIAAGGLLRFATR------------PLQLA
MAV_2240|M.avium_104 PDAAPP--EPAAGVGGGAGWRIAAGGLVRFAAR------------PLRLA
MSMEG_4297|M.smegmatis_MC2_155 PDAPPP--DPVDGPGGGTGLEIAVNGAVRFATR------------PLRLV
TH_2477|M.thermoresistible__bu ADTPPP--EPVQGAGTASDLEIALSGAVRFATR------------PLKLL
MAB_1917|M.abscessus_ATCC_1997 PDAEAP--EPAPGVGGANSLEIAVTGALKWASR------------PLKFA
Mb1791|M.bovis_AF2122/97 PDAPAP--QPVRGTGGGNVLQIAASGLVGFASR------------PVRLA
Rv1760|M.tuberculosis_H37Rv PDAPAP--QPVRGTGGGNVLQIAASGLEGFASR------------PVRLA
MUL_1818|M.ulcerans_Agy99 PEPRPPQ-EETVGFVGFQIPRLERRAVGALINVGIM--------TPFRIA
MLBr_01244|M.leprae_Br4923 RDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAG
:. . . : . .
Mflv_5212|M.gilvum_PYR-GCK RVVPVATSLVTNTVSRALSGTAMALPFSAPSTPFNAPLTSDRNIAFAQLD
Mvan_1065|M.vanbaalenii_PYR-1 RVIPETTAVIAKTVTRALTGKTMAAPFSAPATRFNAQLTSERCLALVQLD
MMAR_3298|M.marinum_M NVVPETVSSVVSTLLRAREGLTMARPFTAPRTVFNARVSGRRAVAYAELD
MAV_2240|M.avium_104 SVVPDTAASVLATVRRALDGAAMARPFAAPTTVFNARISNRRCIAYAELN
MSMEG_4297|M.smegmatis_MC2_155 NVVPSTLNTVVDTVRRARNGRTMAAPFAAPRTAFNANITGHRNIAFAQLD
TH_2477|M.thermoresistible__bu NVLPTTANSVLDTVRRARAGRTMARPFAAPSTPFNANVTGRRNVAFTQLD
MAB_1917|M.abscessus_ATCC_1997 KLLPATIGVIPAWLERSKRGEAMSAPFSAPRTSFNSTITSRRNVGYAQLD
Mb1791|M.bovis_AF2122/97 TVVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLD
Rv1760|M.tuberculosis_H37Rv TVVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLD
MUL_1818|M.ulcerans_Agy99 RLVEQTVRQQIAALGVSARP---PRYFDAPKTRFNAHVSPHRRVSGCRIE
MLBr_01244|M.leprae_Br4923 RAILRPASTVSGVVGYVRSGIRVLSQAAEPSPLLRQRSLATR-TEAIEIQ
: . : * . :. * .::
Mflv_5212|M.gilvum_PYR-GCK LDDVKKVKNQAEVKVNDVVMALCAGALRGYLDERGALPDKPLIAVVPSSV
Mvan_1065|M.vanbaalenii_PYR-1 LNDVKKVKDRFAVKVNDVVLALCAGALRGFLADRDELPDKPLIAVVPASV
MMAR_3298|M.marinum_M LEDIKAVKNHFGVKVNDVVMGLVSGVLRNYLADRDALPTSSLVASVPVSV
MAV_2240|M.avium_104 LDDVKAVKNHFGVKVNDVVMALVSGVLRQYLAERNALPDSSLVASVPISV
MSMEG_4297|M.smegmatis_MC2_155 LEDIKTVKNHFDVKVNDVVMALVSGVLRTFLSHRDELPDNSLVAMVPVSV
TH_2477|M.thermoresistible__bu LEDVKRIKDHFGVKVNDVVMALTSGALRSYLLERDQLPDSPLIAMVPVSV
MAB_1917|M.abscessus_ATCC_1997 LEDVRTVKNHFGVKVNDVVMAICAGALRKYLDDRGELPDNSLVAMVPVSV
Mb1791|M.bovis_AF2122/97 MRDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSV
Rv1760|M.tuberculosis_H37Rv MRDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSV
MUL_1818|M.ulcerans_Agy99 LARAKAVKDAFGVKLNDVVLATVAGAAREYLKKRDELPAKPLIAQIPVST
MLBr_01244|M.leprae_Br4923 LSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALG-VSISTLPMAVPVNV
: : . .:**. :. *. * : . :. .* :* ..
Mflv_5212|M.gilvum_PYR-GCK HGQTDRPGR-NQLSGMFCNLHTDIEDPLDRLYAIGASNVRAKEHSGSLGP
Mvan_1065|M.vanbaalenii_PYR-1 HDISDRPGR-NQLSGMFCNLHTDVEDPVQRLRAIAESDTRAKEHSASLGP
MMAR_3298|M.marinum_M HGKSDRPGR-NQVSAMFSSLHTEIADPAERLNAIAHGNTVAKGHSSAIGA
MAV_2240|M.avium_104 HGKSDRPGR-NQVSAMFASLHTEIADPVQRLKAIAHANSLAKEHSSAIGA
MSMEG_4297|M.smegmatis_MC2_155 HDRSDRPGR-NQVSGMFSPLQTHIADPAERLRAIAEANAVAKQHSSAIGA
TH_2477|M.thermoresistible__bu HDKTDRPGR-NHVSGMFSRLETTIEDPAERLRAIANANSVAKQHSSAIAA
MAB_1917|M.abscessus_ATCC_1997 HEKSDRPGR-NQVSGMFSRLETNVDDPVERLNAIAAANNIAKDHTAVLGA
Mb1791|M.bovis_AF2122/97 HDKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGP
Rv1760|M.tuberculosis_H37Rv HDKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGP
MUL_1818|M.ulcerans_Agy99 RTDQTKEDVGNQISSMTASLATHINDPAERLKAIHESTQNAKEMAKALSA
MLBr_01244|M.leprae_Br4923 RTEADVVGS-NRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNII
: . *: : ** *: * : .
Mflv_5212|M.gilvum_PYR-GCK SMLMDLAQSVSRTMFGWLLGGLSRTSLGNTAI--HNVIISNVAGPPTTLY
Mvan_1065|M.vanbaalenii_PYR-1 TLLVDLAQSLSRGAFETLLGVLSHTPLTHTAI--HNCVISNVAGPTTTLY
MMAR_3298|M.marinum_M TLLQDWSQFAAPAVFGAAMRVYASSRLTESLP-VHNLVVSNVPGPQLPLY
MAV_2240|M.avium_104 SLLQDWTQFAAPAVFGIAMRLYARTRFTDSMP-VHNLVVSNVPGPQLPLY
MSMEG_4297|M.smegmatis_MC2_155 TLLQDWTQFAAPAVFGTAMRVYAASRLSGAKP-VHNLVVSNVPGPQVPLY
TH_2477|M.thermoresistible__bu SLLQDWTQFAAPAVFGVAMRVYAASRLGEAKP-VHNLVVSNVPGPQVPLY
MAB_1917|M.abscessus_ATCC_1997 TLLQDWSQFAAPAVFGTAMRVYSRIRLADRHPVIHNLVVSNVPGPQVPLY
Mb1791|M.bovis_AF2122/97 TLLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLY
Rv1760|M.tuberculosis_H37Rv TLLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLY
MUL_1818|M.ulcerans_Agy99 HQIMGLTETTPPGLLHLAARAYTATGLSHNLA-PINLVVSNVPGPQFPLY
MLBr_01244|M.leprae_Br4923 GSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQY
: : . . . . *
Mflv_5212|M.gilvum_PYR-GCK SGGAEITGLYPLGPIFPGSGLNITVMSMGDKLNVGIISCPKLTDDLWDLA
Mvan_1065|M.vanbaalenii_PYR-1 SGGAAITALYPLGPIFHGSGLNITVMSLGDTLNVGILSCPQLVDDLWDLA
MMAR_3298|M.marinum_M MLGCEVKAMYPLGPIFHGSGLNVTVMSLNGKLDVGLVACPELLPDLWQMA
MAV_2240|M.avium_104 LLGCEVKAMYPLGPIFHGSGLNITAMSLRGKLDVGLIGCPDLVPDLWELA
MSMEG_4297|M.smegmatis_MC2_155 FLGAEVKAMYPLGPIFHGSGLNITVMSLTGKLDVGIISCPELLPDLWDMA
TH_2477|M.thermoresistible__bu FLGAEVKAMYPLGPIFHGSGLNITVMSLTGRLNVGMVSCPELMPDLWELA
MAB_1917|M.abscessus_ATCC_1997 FLGAQVIGMYPLGPIFHGAALTVTVMSLDGKLNVGLISCPDLMPDLGTLT
Mb1791|M.bovis_AF2122/97 FLGCRMDSMFPLGPSLATRASTSPSCPSTGNWVSALSPAPTCCRTCGAWQ
Rv1760|M.tuberculosis_H37Rv FLGCRMDSMFPLGPLLGNAGLNITVMSLNGELGVGIVSCPDLLPDLWGVA
MUL_1818|M.ulcerans_Agy99 MAGARLDSLVPLGPPVMDVALNITCFSYQEHLDFGFVTTPEVANDIDEMA
MLBr_01244|M.leprae_Br4923 GIGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVL
* . .
Mflv_5212|M.gilvum_PYR-GCK DRFD-------AELADLLARS------------
Mvan_1065|M.vanbaalenii_PYR-1 DRFD-------GELTELLHHC------------
MMAR_3298|M.marinum_M DEFA-------TVMEELLAETG-----------
MAV_2240|M.avium_104 DEFA-------VAMEELRAAAR-----------
MSMEG_4297|M.smegmatis_MC2_155 DDFA-------VALDELLDATKRA---------
TH_2477|M.thermoresistible__bu EGFE-------RALRELLDTVG-----------
MAB_1917|M.abscessus_ATCC_1997 DDFG-------VALEELKARI------------
Mb1791|M.bovis_AF2122/97 TGFPRRSKSCWSAVMTSRKAATTRTPESYVQNR
Rv1760|M.tuberculosis_H37Rv DGFP-------EALKELLECSDDQPEGSNHQDS
MUL_1818|M.ulcerans_Agy99 DLIEP-------ALAELERAAGL----------
MLBr_01244|M.leprae_Br4923 ALAG---DPTPHAVPASFAARSSGSPAGWLSSS
: