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M. marinum M MMAR_2461 (-)

annotation: PE-PGRS family protein
coordinates: 2976136 - 2983359
length: 2407

MSFVTAVPELVESAAQDLAGIRSALVEAAQAVAAPTTALAAAGEDEVSAAIAALFGTFGQEYQAVSAQAA
SFHESFVRVLSGAAASYVEAEVANGAALLAGESAAAAVSGGFSGGLTAGLSAELALQAANSLATAFGSGV
SGLALQTGGALVSGLGTGLVQTGEVIVSAGQALQNLGSFMAGAGAGLSAQASAALTQAMNLGGSLSAQLG
ASLSGNFNLALPELIAGFNNGLTGLIQTGQTITTSLIGSAGSGLGALFQTGGTVLTNFGSALPEFAAQLS
GAISATVGSSLPGLVGAFDSGFTGLVQAGQSLATNLAGSVGGGLDALIQTGETLAGGLTASLSAPVLAAQ
LSAALQASFGTSLPELVAAFTGGLNGLVQAGQTLAANVAGNFGGGLSGLLEAGQVLMANLAGGFSLPALA
AQISAAVQASFGASFPEVVAAFTGGLSGLVQAGQTLAANLVGGFSLPALAAQISAAVQASFGASFPEAVA
AFTGGLNGLVQAGQTLAANLAGSLGGGFNALVEVGQALAANLVGGFSLPTLAAELSAALQASFGASFPEA
VAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALIEVGQALAANLVGGFSLPALAAQISAALQASFGASFP
EAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALIEVGQALAANLVGGFSLPTLAAQISAALQASFGAS
FPEAVAAFTGGLNGLVQAGQTLAANLAGSFGGGLTGLLEAGQVLMANLAGGFSLPTLAAQISAALQASFG
ASFPEAVAAFTGGLNGLVQAGQTLAANLAGSLGGGFNALVEVGQALAANLVGGFSLPTLAAQISAALQAS
FGASFPEAVAAFTGGLNGLVQAGQTLAANLAGSLGGGFNALIEVGQALAANLVGGFSLPALAAQISAALQ
ASFGASFPEVVAAFTGGLNGLVQAGQTLAANLAGSFGGGFNALVEVGQALAANLVGGFSLPALAAQISAA
LQASFGASFPEVVAAFTGGLNGLVQAGQSLAANLAGSFGGGFNALIEVGQALAANLVGGFSLPALAAQIS
AALQASFGASFPEVVAAFTGGLNGLVQAGQTLAANLAGSFGGGLSGLLEAGQVLMANLVGGFSLPALAAQ
ISAALQASFGASFPEVVAAFTGGLNGLVQAGQSLAANLAGSFGGGLSGLLQAGQVLMANLVGGFSLPTLA
AELSAALQASFGASLPEAVAAFTGGLNGLVRAGQTLAANLAGSFGGGLSGLLQAGQVLMANLVGGFSLPT
LAAELSAALQASFGASLPEAVAAFTGGLNGLVQAGQTLAANLAGSFGGGLSGLLEAGQVLMANLVGGFSL
PTLAAELSAALQASFGASFPEAVAAFTGGLNGLVQAGQTLAANLAGSFGGGLTGLLEAGQVLMANLVGGF
SLPTLAAELSAALQASFGASFPEVVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALVEVGQALAANLVG
GFSLPTLAAELSAALQASFGASFPEVVAAFTGGLNGLVQAGQSLAANLAGSFGGGFNALIEVGQALAANL
VGGFSLPALAAQISAALQASFGASFPEVVAAFTGGLNGLVQAGQTLAANLAGSFGGGLSGLLEAGQVLMA
NLVGGFSLPALAAQISAALQASFGASFPEVVAAFTGGLNGLVQAGQSLAANLAGSFGGGLSGLLQAGQAL
MANLVGGFSLPTLAAELSAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALIEVGQ
ALAANLVGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSFGGGLTGLLEA
GQVLMANLAGGFSLPTLAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALI
EVGQALAANLVGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQTLAANLAGSLGGGFNA
LIEVGQALAANLAGGFSLPTLAAELSAALQASFGASFPEVVAAFTGGLNGLVQAGQTLAANLAGSLGGGF
NALVEVGQALAANLVGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGG
GFNALIEVGQALAANLVGGFSLPTLAAQISAALQASLGTSFPELMAGFTGGFTGLLQTGQSLAGNLVGSF
GGGLDALIQTGQNVAANLVGAFNAPALLAGLNSGLNGLVQTGASLAGNLAGAFGAGLPELATQLSAALSA
SLSGDLSAELSAALTASLANTASGLLSGLAQTGATLAGGIGGGLLGLIGTGETLASSLAGGVSGLLGTGE
SLLMIWQNATAEVTGALSDAVVASIGVGLPGLSQAAVTLSTGIANASVGLTQTGGVIVSALDNAALGITG
DISAALANLQLAIQAALNASFGVQVAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2461--100% (2407)PE-PGRS family protein
M. marinum MMMAR_5294-7e-7626.69% (2507) PE-PGRS family protein
M. marinum MMMAR_4287-3e-6533.21% (828) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3538PE_PGRS542e-4527.47% (1485) PE-PGRS family protein
M. gilvum PYR-GCKMflv_5091-5e-1225.58% (684) triple helix repeat-containing collagen
M. tuberculosis H37RvRv3508PE_PGRS543e-5726.82% (2010) PE-PGRS family protein
M. leprae Br4923MLBr_01183-6e-1033.33% (96) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-1e-1323.93% (723) hypothetical protein MAB_4284c
M. avium 104MAV_0534-4e-1644.90% (98) PE family protein
M. smegmatis MC2 155MSMEG_2991-3e-0924.47% (425) permease of the major facilitator superfamily protein
M. thermoresistible (build 8)TH_4429-2e-1121.33% (2166) PUTATIVE -
M. ulcerans Agy99MUL_4367-3e-4127.95% (1009) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-5e-1126.54% (682) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2461|M.marinum_M               -------------------------------------MS-FVTAVPELVE
MAV_0534|M.avium_104                -------------------------------------MS-FLMVRPEILD
MLBr_01183|M.leprae_Br4923          -------------------------------------MPLFLNAEPQALT
Mb3538|M.bovis_AF2122/97            --------------------------------------MSFVLIAPEFVT
Rv3508|M.tuberculosis_H37Rv         --------------------------------------MSFVLIAPEFVT
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------MSFVSVGPGLLE
TH_4429|M.thermoresistible__bu      VTTPVGSIRIDLSIDGSNLGDEITAAVQKHVKAALGELNEVLAEVQAQME
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------------MSIIDFIL
MSMEG_2991|M.smegmatis_MC2_155      -----------------------------------------MRIRTAAPG
                                                                                      

MMAR_2461|M.marinum_M               SAAQDLAGIRSALVEAAQAVAAPT--------TALAAAGEDEVSAAIAAL
MAV_0534|M.avium_104                AAARELHGINAAVLQSNSAAVTPT--------TALAPAAADVVSLVTAAR
MLBr_01183|M.leprae_Br4923          AAANTLEGLSAATVASNAAAAQLT--------TEIAPPAADDVSILLAHF
Mb3538|M.bovis_AF2122/97            AAAGDLTNLGSSISAANASAASAT--------TQVLAAGADEVSARIAAL
Rv3508|M.tuberculosis_H37Rv         AAAGDLTNLGSSISAANASAASAT--------TQVLAAGADEVSARIAAL
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------------MVT
Mvan_1264|M.vanbaalenii_PYR-1       --------MMFLAPPGGPGPISAA--------IQLTSTGSEATEPWYVVS
MUL_4367|M.ulcerans_Agy99           AAARDLAGLGAGLREANLAAAGAT--------VGVLPAAGDEVSAAIAEL
TH_4429|M.thermoresistible__bu      STSRASASAATGVGQAGKAAREATGGMSDMQQASQAAAQATKTAGDAARA
MAB_4284c|M.abscessus_ATCC_199      NLFRDPVEAASYVADPEAALANAG-------LSAVSAAQVGAVMPVVAES
MSMEG_2991|M.smegmatis_MC2_155      TTTPTLALIILLALLNAVTPFSVD--------MYMSAFPAMAVEFGTSAS
                                                                                      

MMAR_2461|M.marinum_M               FGTFGQEYQAVSAQAASFHESFVRVLSGAAASYVEAEVANGAALLAGESA
MAV_0534|M.avium_104                FSRHGLAFQEVSAQAAQLRDQFATTLGISAGSYAAAEIAN----------
MLBr_01183|M.leprae_Br4923          FSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN----------
Mb3538|M.bovis_AF2122/97            FGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQI
Rv3508|M.tuberculosis_H37Rv         FGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA------AAEQI
Mflv_5091|M.gilvum_PYR-GCK          FG--------------------------GGATPTPTSLG------AAAVD
Mvan_1264|M.vanbaalenii_PYR-1       FG--------------------------GSGAPTPNNLA------ASLVD
MUL_4367|M.ulcerans_Agy99           FGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNMWPLQELEQQ
TH_4429|M.thermoresistible__bu      AGSGMDDMGRASDGAADRTSKAGRAASQASGEFGRFSRAAERASAVSKQL
MAB_4284c|M.abscessus_ATCC_199      VASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS----------
MSMEG_2991|M.smegmatis_MC2_155      VVQLTLTTFLIGLATGQLFIGQLSDRLGRRGPLLVGIVAC---------L
                                                                  .                   

MMAR_2461|M.marinum_M               AAAVSGGFSGGLTAGLSAELALQAANSLATAFGSGVSGLALQTGGALVSG
MAV_0534|M.avium_104                TAAVG---------------------------------------------
MLBr_01183|M.leprae_Br4923          HDSL----------------------------------------------
Mb3538|M.bovis_AF2122/97            VLGVINAPTQALLGRPLIGDGANATT-PGGAGGAGGLLFGNGGAG-AAGA
Rv3508|M.tuberculosis_H37Rv         VLGVINAPTQALLGRPLIGDGANATT-PGGAGGAGGLLFGNGGAG-AAGA
Mflv_5091|M.gilvum_PYR-GCK          LSGTSCG---------LICNGQ------DGTGQNGGILFGNGGSGWNSDV
Mvan_1264|M.vanbaalenii_PYR-1       LSGTSCG---------LICNGQ------DGTGQNGGILFGNGGSGWNSEI
MUL_4367|M.ulcerans_Agy99           ALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGNGGNG-GLGA
TH_4429|M.thermoresistible__bu      GSGVGQAASGFVRAGDAVLGAVGKFAKWTGIGAAVSGAIGGVAGSFSVLQ
MAB_4284c|M.abscessus_ATCC_199      -PSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDL
MSMEG_2991|M.smegmatis_MC2_155      VASLLCAVSPSIEVLIMLRFVQG---------FAGAAGIVIARAIISDRS
                                      .                                               

MMAR_2461|M.marinum_M               LGTGLVQTGEVIVSAGQALQNLGSFMAG-AGAGLSAQASAALTQAMNLGG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            PGQAGGPGGPAGLWGNGGPGGAGGSGGG--TGGAGGAGGWLFGVGGAGGV
Rv3508|M.tuberculosis_H37Rv         PGQAGGPGGPAGLWGNGGPGGAGGSGGG--TGGAGGAGGWLFGVGGAGGV
Mflv_5091|M.gilvum_PYR-GCK          VGMDGGNGGNGGLFGGNGGNGGNGLGGG--NGGNGGNAG-AFALFGNGGN
Mvan_1264|M.vanbaalenii_PYR-1       AGVSGGNGGNAGLFGGNGGNGGNGLGSG--DGGNGGDAG-LFSLFGRGGN
MUL_4367|M.ulcerans_Agy99           AGANGGAGGSAGLIGTGGVGGAGGVGAAGMTGGSGGAGGGGGWLWGAGGS
TH_4429|M.thermoresistible__bu      LGMNRLTSIENARSTLQGLGHDARSVEGIMDSALTAVKGTAFGLGEAATV
MAB_4284c|M.abscessus_ATCC_199      SFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIIN
MSMEG_2991|M.smegmatis_MC2_155      KGSQAAKLYSVMMVIGVLAPILAPVLGGQVVAGFGWRAVFLALAGLNLVM
                                                                                      

MMAR_2461|M.marinum_M               SLSAQLGASLSGNFNLALPELIAGFNNGLTGLIQTGQTITTSLIGSAGSG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAG
Rv3508|M.tuberculosis_H37Rv         GGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELLFGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          GGNGG-VGVVGATG-----AVGAPGVAGATGATGVTSG----VVGGNGED
Mvan_1264|M.vanbaalenii_PYR-1       GGNGG-VGIAGATG-----AVGAPGVAGATGATGVTSN----VTGGNGAD
MUL_4367|M.ulcerans_Agy99           GGAAG-AGGSGGSGGWLWGNAGQTAGAGVGGAGGAGGAG---DAGDQGVS
TH_4429|M.thermoresistible__bu      AASAVAAGVQPGEDLTRTLKLVGDAAAIAKTDMQSMGAIFNKVATSNKVQ
MAB_4284c|M.abscessus_ATCC_199      ADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNIN
MSMEG_2991|M.smegmatis_MC2_155      LLGALFMAGESLPPEARRPAGLKAFAGSAASVLTNRR-------------
                                                                                      

MMAR_2461|M.marinum_M               ----------LGALFQTGGTVLTNFGSALPEFAAQLSGAISATVGSSLPG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            ----------GAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGG
Rv3508|M.tuberculosis_H37Rv         ----------GAG---TDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK          ----------AVG-------YGATGAAGAAGAAG------AAGAAGAVGS
Mvan_1264|M.vanbaalenii_PYR-1       ----------AVG-------YGATGAAGAAGAAG------AAGKAGAVGS
MUL_4367|M.ulcerans_Agy99           ----------GVA-------PGEAGAVGFAGGAGGAGGAGGNGVGGGVNG
TH_4429|M.thermoresistible__bu      GEVMAQLHDRGIPILQLLSEEIGKTAEETAKMASDGKIDFETFRNAIERG
MAB_4284c|M.abscessus_ATCC_199      ----------------------DSFNTDRSTNIGSGNTTNTEIGSHNQAN
MSMEG_2991|M.smegmatis_MC2_155      -----------------------FMGYTLTLSCSGAAMFSYISASPFVLQ
                                                                                      

MMAR_2461|M.marinum_M               LVGAFDSGFTGLVQAGQSLATNLAGSVGGGLDALIQTGETLAGGLTASLS
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            QGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGG
Rv3508|M.tuberculosis_H37Rv         QGGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGG
Mflv_5091|M.gilvum_PYR-GCK          AGAAGEAGETG-TWGNAGLPGKAGDAGGAGAVG----AAGAAGTVGTAGA
Mvan_1264|M.vanbaalenii_PYR-1       AGTAGSAGAPG-VWGNAGLPGAAGAAGGAGAIG----TAGVAGAAGTAGA
MUL_4367|M.ulcerans_Agy99           AGGAGGAGGVGGGGGAGASGVGAGVAGGDGGTG----GAGGAAGVGGAAG
TH_4429|M.thermoresistible__bu      MGGAALKAGETFEGAMANMRAALGRLGAEILKGPFESAPAVIGRVTEGID
MAB_4284c|M.abscessus_ATCC_199      IGTSTSAGGSAAVGGNAGLAGNAGLAGNAGLAG----NAGLAGNAGLAGN
MSMEG_2991|M.smegmatis_MC2_155      NIIGLSPRAFSFTFGGCALAVAVSGVISARLVGRFGPRKLLLGGVSAMVV
                                                                                      

MMAR_2461|M.marinum_M               APVLAAQLSAALQASFGTSLPELVAAFTGGLNGLVQAGQTLAANVAGNFG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            QGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGA
Rv3508|M.tuberculosis_H37Rv         QGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGA
Mflv_5091|M.gilvum_PYR-GCK          TGGTG-------------TGANGGAGGVGGVGGTG-------AAGAAGGA
Mvan_1264|M.vanbaalenii_PYR-1       TGGTG-------------VGGNGGAGQAGGIGGTG-------AAGAAGQA
MUL_4367|M.ulcerans_Agy99           TGGTGG------------AAGVAGTGGDGGDGGAGG------AGSDASLA
TH_4429|M.thermoresistible__bu      VATDAVKGMVTYLRTGEVTDTFRDVFGRGDMSRRVLAGLERVRTVARQVR
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAG----------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA
MSMEG_2991|M.smegmatis_MC2_155      VAALMLLN--------VTVGGVVPAVTVALMACFMGTVGFTFANATTLAI
                                                                                      

MMAR_2461|M.marinum_M               GGLSGLLEAG----QVLMANLAGGFSLPALAAQISAAVQASFGASFPEVV
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            VGVGGTGGQG----GAG---------------------------------
Rv3508|M.tuberculosis_H37Rv         VGVGGTGGQG----GAGGAGAAGADAPASTGLTGGTGFAGGAGGVGGQGG
Mflv_5091|M.gilvum_PYR-GCK          GGLGETGTTG----GAG---------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GTAGETGVTG----GVG---------------------------------
MUL_4367|M.ulcerans_Agy99           GQAGFAGGSG----GAG---------------------------------
TH_4429|M.thermoresistible__bu      DGFEELQAAWRGDDGAADWATKAVDFVRDSLARVWDIAKQLGPALAGIAA
MAB_4284c|M.abscessus_ATCC_199      GNAGLAGNAG----------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      GEVRHAAGTG----------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AAFTGGLSGLVQAGQTLAANLVGGFSLPALAAQISAAVQASFGASFPEAV
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -----------------------GMGGSGADNASGIGADGGAGGTGGNAG
Rv3508|M.tuberculosis_H37Rv         NAIAGGINGSGGAGGTGGQGGAGGMGGSGADNASGIGADGGAGGTGGNAG
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------GVGGQGTAGGTG---G
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------GIGGQGTEGGTG---G
MUL_4367|M.ulcerans_Agy99           ----------------------------------GVGGSAGAGGVN---G
TH_4429|M.thermoresistible__bu      SFAKASAAVGVSAWTIFLRTAEALVPILTTIADLITSHQGVVTALVAAYA
MAB_4284c|M.abscessus_ATCC_199      -----------------------------------LAGNAGLAGNAGLAG
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AAFTGGLNGLVQAGQTLAANLAGSLGGGFNALVEVGQALAANLVGGFSLP
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGGAGGAAGTGGTGGVVGAAGKAGIGG-------TGGQGGAGGAGSAGTD
Rv3508|M.tuberculosis_H37Rv         AGGAGGAAGTGGTGGVVGAAGKAGIGG-------TGGQGGAGGAGSAGTD
Mflv_5091|M.gilvum_PYR-GCK          VGGIGGAGSTGAVGGVGGKGIQGGQGL-------QGGKGGDGGAGGKGGD
Mvan_1264|M.vanbaalenii_PYR-1       VGGVGGVGATGGAGGVGGKGIQGGQGL-------QGGQGGDGGTGGTGGD
MUL_4367|M.ulcerans_Agy99           SGGDGGAGAAGGAGGAS--ATVAGSGG-------VGGDGGAGGAAGGGVG
TH_4429|M.thermoresistible__bu      LLKTGFIGAAVAAKGLAVIKTVTGWMTG-----LIGVTTAAGTVMSTTLT
MAB_4284c|M.abscessus_ATCC_199      NAGLAGNAGLAGNAGLAGNAGLAGNAG------LAGNAAVAGNAAVAGNA
MSMEG_2991|M.smegmatis_MC2_155      ----SAVIGFLQYGLGAVASPLVGLAG--------EHSAVPMGVAMFTCA
                                                                                      

MMAR_2461|M.marinum_M               TLAAELSAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            ATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAG
Rv3508|M.tuberculosis_H37Rv         ATATGATGGTGFSGGAGGAGGAGGNTGVGGTNGSGGQGGTGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK          ADSMGSAGATGGKGGNGGNGGRGGLFGKGGNAGNGADGGTGGAGGAG---
Mvan_1264|M.vanbaalenii_PYR-1       ATSMGEAGATGGKGGNGGNGGRGSLFGRGGNAGNGGNGGTGGNGGNG---
MUL_4367|M.ulcerans_Agy99           AASLGGDGGHAGAGGAGGEGLSGG-FNTGAAGGIGGAGGAGGTGGDSG--
TH_4429|M.thermoresistible__bu      TVATDADGLGSSMGGLGERTKKGMRETLRSLKALRGEIGTTMLMAGTAAT
MAB_4284c|M.abscessus_ATCC_199      AVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGG--
MSMEG_2991|M.smegmatis_MC2_155      ALAATALLVLTRGHIPSYDDELADLDADLTAVSAGESTAR----------
                                                                                      

MMAR_2461|M.marinum_M               FNALIEVGQALAANLVGG------------------------FSLPALAA
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GVGADNPTGIGGAGGTGG--------------------------------
Rv3508|M.tuberculosis_H37Rv         GVGADNPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGGTGGQG
Mflv_5091|M.gilvum_PYR-GCK          -----------GTGGTGG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -----------GTGGTGG--------------------------------
MUL_4367|M.ulcerans_Agy99           -----------GVGGVNG--------------------------------
TH_4429|M.thermoresistible__bu      ATSSGIAQTIGALSSVAG--------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               QISAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNAL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            ------------------AGGTGGTGGAAGAGGAGGAVGTGGTGGVVGDV
Rv3508|M.tuberculosis_H37Rv         GAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSV
Mflv_5091|M.gilvum_PYR-GCK          ------------------AGGTGGTGGTGGIGGAG---STGGTG------
Mvan_1264|M.vanbaalenii_PYR-1       ------------------NGGTGGTGGTGGIGGAG---STGGTG------
MUL_4367|M.ulcerans_Agy99           ------------------DGGAGGGGGRGGDGGSS--TSTSGVG------
TH_4429|M.thermoresistible__bu      -----GALAGSIFGPAGAAIGAGIGGGIALASYLLGENARAARAAAAAQA
MAB_4284c|M.abscessus_ATCC_199      ------------------GAHTGVGGGVSTG-------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               IEVGQALAANLVGGFSLPTLAAQISAALQASFGASFPEAVAAFTGGLNGL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GNAGIGGTGGKGGAGGTG------------------------------FA
Rv3508|M.tuberculosis_H37Rv         GNAGIGGTGGTGGVGGAGGAGAAAAAGSSATG-------------GAGFA
Mflv_5091|M.gilvum_PYR-GCK          ---GTGGTGGTGGTGGTG--------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---GTGGTGGTGGTGGTG--------------------------------
MUL_4367|M.ulcerans_Agy99           ---GAGGAGGNGGNAGFG-----------------------------VSA
TH_4429|M.thermoresistible__bu      ELAQQVQRAKEAQLASLGAQKELNAALLESAGVVDEAAVAAVARTIDNLP
MAB_4284c|M.abscessus_ATCC_199      --VGVGSHVGGGISESLG--------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VQAGQTLAANLAGSFGGGLTGLLEAGQVLMANLAGGFSLPTLAAQISAAL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GGAGGAGGQGGSSG-AGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGG
Rv3508|M.tuberculosis_H37Rv         GGAGGEGGAGGNSG-VGGTNGSGGAGGAGGKGGTGGAGGSGADNPTGAGF
Mflv_5091|M.gilvum_PYR-GCK          -GTGGTGGTGGTGG-KGGTGGTGGAGGTGGDGGTGGTGG-----------
Mvan_1264|M.vanbaalenii_PYR-1       -GTGGTGGTGGTGG-KGGTGGTGGDGGTGGTGGTGGTGG-----------
MUL_4367|M.ulcerans_Agy99           GGTGGSAGDGGAGGGAGGVDGVGGASGNGGAAGAGGAGGSGIG-------
TH_4429|M.thermoresistible__bu      EMLRGRLSDEQVQGVVESIQKLGVSSESLASQLTRGGPALDATLAALRAM
MAB_4284c|M.abscessus_ATCC_199      -GSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG---------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               QASFGASFPEAVAAFTGGLNGLVQAGQTLAANLAGSLGGGFNALVEVGQA
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGGTGGTGGAAGAGGAGGAIGTGGTGGAVGSVGNAGIG------------
Rv3508|M.tuberculosis_H37Rv         AGGAGGTGGAAGAGGAGGATGTGGTGGVVGATGSAGIGG-----------
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGTGGTGGTGGAG--DGTGGTG------------------------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGTGGTGGTGGAG--DGLGGTG------------------------
MUL_4367|M.ulcerans_Agy99           AGIDGGAGGAGGTGGAAGFPGGGGTTG-----------------------
TH_4429|M.thermoresistible__bu      GGPDGERAADALLGVAARFDHARTRAEAAAPALSEMAQKMG---------
MAB_4284c|M.abscessus_ATCC_199      GGISESLGGSGSVGGSTAVGGGAHTG------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               LAANLVGGFSLPTLAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQT
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -----------------------------------------------GTG
Rv3508|M.tuberculosis_H37Rv         -----AGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGAG
Mflv_5091|M.gilvum_PYR-GCK          -----------------------------------------------GTG
Mvan_1264|M.vanbaalenii_PYR-1       -----------------------------------------------GTG
MUL_4367|M.ulcerans_Agy99           ---------------------------------------------AWGTG
TH_4429|M.thermoresistible__bu      -------VDVLQAADDLSVALKAVPQNIPLNMDMPGAEALVGLLREAGAA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               LAANLAGSLGGGFNALIEVGQALAANLVGGFSLPALAAQISAALQASFGA
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GTGGVGGAGGAGAAAAAGSSATGGAGFAGGAG-----------------G
Rv3508|M.tuberculosis_H37Rv         GAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAG
Mflv_5091|M.gilvum_PYR-GCK          GTGGQGGQGGQG-------------------------------------G
Mvan_1264|M.vanbaalenii_PYR-1       GTGGFGGQGGQG-------------------------------------G
MUL_4367|M.ulcerans_Agy99           GAGGAGGAGGAGDHGGVG------------------------------VN
TH_4429|M.thermoresistible__bu      VEVLGDGTVHLDVNDERVRDAITVVDSLGWAIKQVPDTKQIEITVKTDEA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               SFPEVVAAFTGGLNGLVQAG-------QTLAANLAGSFGGGFNALVEVGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            EGGAGGNSGVGGTNGSGGAG---------GAGGKGGTGGAGGSGADNPTG
Rv3508|M.tuberculosis_H37Rv         DGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGASTTSINA
Mflv_5091|M.gilvum_PYR-GCK          TGGTGGQGGLGGGGGTGGQG---------GTGGTGGQGGTGG--------
Mvan_1264|M.vanbaalenii_PYR-1       TGGTGGQGGLGGVGGTGGTG---------GTGGTGGQGGTGG--------
MUL_4367|M.ulcerans_Agy99           PGDSGTAGWAGGAGGAGGAG---------GSAAFNGVNGAGG--------
TH_4429|M.thermoresistible__bu      ALQRFISQMTTEMQKFTTLWITPQLTGEIPAGQPRPNPTAGGNALDPGFF
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ALAANLVGGFSLPALAAQISAALQASFGASFPEVVAAFTGGLNGLVQAGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGFAGGAGGTGGAAGAGGAG--------------GATGTGGTGGVVGATG
Rv3508|M.tuberculosis_H37Rv         NGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFGGAAG
Mflv_5091|M.gilvum_PYR-GCK          ---TGGTGGTGGTGGAGGDG------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       ---TGGTGGTGGTGGAGGDG------------------------------
MUL_4367|M.ulcerans_Agy99           ---AGGNGGAGGGGGAGASG------------------------------
TH_4429|M.thermoresistible__bu      IPGGRADGGVLPGYSPGRDNMLVPLSGGEGIIIPEAMRALGGSWLYQLNS
MAB_4284c|M.abscessus_ATCC_199      -VGGGVNTGVGVGSHVG---------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               SLAANLAGSFGGGFNALIEVGQALAANLVGGFSLPALAAQISAALQASFG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            SAGIGGAGGRGGDGGDGASGLGLGLSGFDGGQGGQGGDGGSAGAGGINGA
Rv3508|M.tuberculosis_H37Rv         KAGGGGNGGRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAGGINGA
Mflv_5091|M.gilvum_PYR-GCK          --GLGGLGGFGGSGG-------------TGGQGGLGGPGGSTG-----GA
Mvan_1264|M.vanbaalenii_PYR-1       --GLGGLGGFGGVGG-------------TGGQGGQGGPGGSTG-----GA
MUL_4367|M.ulcerans_Agy99           -IGAGVAGGDGGTGG-------------TGGAAGTGGAAGTGG------T
TH_4429|M.thermoresistible__bu      RFRPGISRRGYADGGVHRGSGALPGPVFDTRDDDEPLKLLEDIRDLLAGA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ASFPEVVAAFTGGLNGLVQAGQTLAANLAGSFGGGLSG------LLEAGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GGAGGDGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGN------GGNAGV
Rv3508|M.tuberculosis_H37Rv         GGAGGNGGDGGDGATGAAGLGDNGGVGGDGGAGGAAGN------GGNAGV
Mflv_5091|M.gilvum_PYR-GCK          GGAGG-----------------QAGTAGKGGLFGGSGS------AGKAGA
Mvan_1264|M.vanbaalenii_PYR-1       GGAGG-----------------QAGVAGKGGLFGGSGS------AGTAGV
MUL_4367|M.ulcerans_Agy99           GGAAG-----------------AAGSAGDGGAGGAGGA------GDDGSA
TH_4429|M.thermoresistible__bu      GPTTAPLNVTAREVSTLADRAVGRMAGMTPGGTGPFGTPIAPRHRGYEMA
MAB_4284c|M.abscessus_ATCC_199      -----------------------GGISESLGGSGSVGG------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VLMANLVGGFSLPALAAQISAALQASFGASFPEVVAAFTGGLNGLVQAGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGA
Rv3508|M.tuberculosis_H37Rv         GLTAKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGGLGGA
Mflv_5091|M.gilvum_PYR-GCK          ----------------TGAAGASGGKGAQGATGAQGATGAQGATGATG--
Mvan_1264|M.vanbaalenii_PYR-1       ----------------TGASGASGGKGAQGATGAQGATGAQGATGATG--
MUL_4367|M.ulcerans_Agy99           G----------------VVSGDPGTAGKAGGAGGAGGVGGNGVAGGVN--
TH_4429|M.thermoresistible__bu      AAAISALGGDPEKWLGAEPVSYWRERINESVQAVQQATSAMGPVVSDMGR
MAB_4284c|M.abscessus_ATCC_199      ------------------STAVGGGAHTSAINDALGGSGSVG--------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               SLAANLAGSFGGGLSGLLQAGQVLMANLVGGFSLPTLAAELSAALQASFG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            STTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGAGGGG
Rv3508|M.tuberculosis_H37Rv         STTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGG
Mflv_5091|M.gilvum_PYR-GCK          ------AAGKAGATGAAGAAGAAGSAGTTGAQGSAGTNGANGANGSQGAA
Mvan_1264|M.vanbaalenii_PYR-1       ------ASGAQGSAGSAGSAGVAGSAGTTGAQGSAGTNGANGANGSQGAA
MUL_4367|M.ulcerans_Agy99           ------GSGGAGGAGGAGGTGGAGASGVP-ASVDGGDGGAGGAGGAAGTG
TH_4429|M.thermoresistible__bu      YVEALQEFARTGDLSAVQGVGLSATDSVITAITSARNKKTGRLSDTEIGA
MAB_4284c|M.abscessus_ATCC_199      ------GSTAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAA
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ASLPEAVAAFTGGLNGLVRAGQTLAANLAGSFGGGLSGLLQAGQVLMANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GFGGAAGKAGGGGNGGVGGDGGEGATGLGLDLSGFAGGQGGQGGAGGNAG
Rv3508|M.tuberculosis_H37Rv         GFGGAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGGQGGAGGSAG
Mflv_5091|M.gilvum_PYR-GCK          GKAGATGTTGATGAAGEDGDAGSGGS------------------------
Mvan_1264|M.vanbaalenii_PYR-1       GKAGATGTTGATGAAGDAGDPGSEAV------------------------
MUL_4367|M.ulcerans_Agy99           GSGGSAGNTGAGGAGGAGGAGGSAAS------------------------
TH_4429|M.thermoresistible__bu      LIEQTLGPSGYVGVLDERNASLVKSLQSFRDKVAKGSGTMTGGALVAGLP
MAB_4284c|M.abscessus_ATCC_199      GTGFEAQGHAQGHASETAHTTLPGAEHH----------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VGGFSLPTLAAELSAALQASFGASLPEAVAAFTGGLNGLVQAGQTLAANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGA
Rv3508|M.tuberculosis_H37Rv         AGGINGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGGDGGNAGFGA
Mflv_5091|M.gilvum_PYR-GCK          --GIN--GGAGGAGGAGGE-----------GGEGGDGGKGGAGA------
Mvan_1264|M.vanbaalenii_PYR-1       --DIN--GGAGGAGGAGGE-----------GGEGGAGGAGGDGS------
MUL_4367|M.ulcerans_Agy99           -TGVNGDGGAGGAGGVGGLGGDSAATAG-GGGAGGDGGKGGAGG------
TH_4429|M.thermoresistible__bu      AHTGAATFSTSGLMPATAALGQAVLQMFPQIREIGGYRQDPHPDHPSGRA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AGSFGGGLSG------LLEAGQVLMANLVGGFSLPTLAAELSAALQASFG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GVPGDGGIGG----------TGGAGGAGGAGGAGDAGADGDPSIDGGQGG
Rv3508|M.tuberculosis_H37Rv         GVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSIDGGQGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------EGGAGGGGGAGGS-------------GAGG
Mvan_1264|M.vanbaalenii_PYR-1       --------------------EGGAGGSGGAGGS-------------GTGG
MUL_4367|M.ulcerans_Agy99           --------------------AGVNGVGGGDGGKG------------GTGG
TH_4429|M.thermoresistible__bu      IDIMIPGGTTRGGRNPAGEALGDQIWNWLMSTGIVDPKGSLWKTDVGGDH
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ASFPEAVAAFTGGLNGLVQAGQTLAANLAGSFGGGLTGLLEAGQVLMANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGG
Rv3508|M.tuberculosis_H37Rv         AGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFIGGSGG
Mflv_5091|M.gilvum_PYR-GCK          AGGAGGSGG---------------SGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1       AGGAGGSGG---------------SGGSGGAGGSGGAAGDSD--------
MUL_4367|M.ulcerans_Agy99           AGGAGGAGSDGIIPS---------NGGLGGNGGNGGNGGQAFG-----DG
TH_4429|M.thermoresistible__bu      FDHIHARIAEGMENAAIQAGLIPAAAGTPAASLGGLSATGGATPVFVTNW
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VGGFSLPTLAAELSAALQASFGASFPEVVAAFTGGLNGLVQAGQSLAANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            TGGTGGDAGAGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGF
Rv3508|M.tuberculosis_H37Rv         TGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQDGNGF
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           VGGAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGATEDG---------
TH_4429|M.thermoresistible__bu      PG-TGGMGMPPGLQPILDAAAQGSGEAASNVLGDVMSAVASLGQEDWAKR
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AGSLGGGFNALVEVGQALAANLVGGFSLPTLAAELSAALQASFGASFPEV
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGGQGGQGGAGGNAGAGGINGAGGTGGTGGAGGDGAPATLIGGPDGGDGG
Rv3508|M.tuberculosis_H37Rv         AGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASEGGAGG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           VGGVGCAGGAGGNGGRGDMLFTVG--------------------------
TH_4429|M.thermoresistible__bu      DASYATLNKLVRDRNPMALAAALGLDVEDFTRQGGGHGDITANDGPGYDS
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VAAFTGGLNGLVQAGQSLAANLAGSFGGGFNALIEVGQALAANLVGGFSL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            QGG------------GAGFGSGVAG-------------------------
Rv3508|M.tuberculosis_H37Rv         QGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPSID
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      SGRLYSDTAALLDRTFTSLNAQLAAMRDQMVSVIEQVSHKLNDAALEPIV
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               PALAAQISAALQASFGASFPEVVAAFTGGLNGLVQAGQTLAANLAGSFGG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -----------------------------------AAGAGGNGGKG----
Rv3508|M.tuberculosis_H37Rv         GGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGDGDGFI
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      KAGVQSALEGLKDSVSHAIGTAMGQAAAPPIADAVRQGMASLPIATSGGD
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               GLSGLLEAGQVLMANLVGGFSLPALAAQISAALQASFGASFPEVVAAFTG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -GDGGTGGTG----------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDSGALSQ
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      SGGNAFSGLIPGMASGGPVYGGVAGRDSVPALLMPGEHVLTTDDVARLGG
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               GLNGLVQAGQSLAANLAGSFGGGLSGLLQAGQALMANLVGGFSLPTLAAE
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -GTNFAGGQGG------------------AGGRGGAGGNGANG-------
Rv3508|M.tuberculosis_H37Rv         DGNGFAGGQGGQGGVGGNAGAGGINGAGGTGGTGGAGGDGQNGTTGVASE
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      QSGVYAFRAALARTGGVRGFATGGAVVNDVVGAEFFGVSQIPIIGLVVNI
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               LSAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALI
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         GGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADG
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      LIRVLLSVLGVQIQARDTLLQMTDEFRQFRGDFQAFDASGRLLNDTSALV
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               EVGQALAANLVGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLV
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            -----------------------------------VGDNAAGGDGGNGGA
Rv3508|M.tuberculosis_H37Rv         DPSIDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           ---------------------------------------GSGGTGGDGGG
TH_4429|M.thermoresistible__bu      DRAQSSEEMAAQERIRILKIVIEALIRYIIEKVIVPIGKAVANAAISAGA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               QAGQSLAANLAGSFGGGLTGLLEAG--QVLMANLAGGFSLPTLAAQISAA
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GGLGGGGGTGGTNGNGGLGGGGGNG--GAGGAGGTPTGSGTEGTGGDGGD
Rv3508|M.tuberculosis_H37Rv         GGLGGGGGTGGTNGNGGLGGGGGNG--GAGGAGGTPTGSGTEGTGGDGGD
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           GGSASGSGTGGSGGTGGVGGIGGDG--KLG--------------------
TH_4429|M.thermoresistible__bu      SAAGAAINTQAPGVGGIVSSLITAAGQAGVDIIADVGTDLALAISETVIA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               LQASFGASFPEAVAAFTGGLNGLVQAGQSLAANLAGSLGGGFNALIEVGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            AGAGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGA
Rv3508|M.tuberculosis_H37Rv         AGAGGNGGSATGVGNGGNGGDGGNGGDGGNGAPGGFGGGAGAGGLGGSGA
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           ----------------GFGGDGGDGGDGGFGVIGGQGGGGGFGGLGGTGA
TH_4429|M.thermoresistible__bu      VVAEGLQSLFPDLMTTIFGGGLLSVLLDPIGNILGNTFGGLLGGITSLLA
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ALAANLVGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            GGGTDGDDGNGGSPGTDGS-------------------------------
Rv3508|M.tuberculosis_H37Rv         GGGTDGDDGNGGSPGTDGS-------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           GG-APSDKGINGEPGNPG--------------------------------
TH_4429|M.thermoresistible__bu      GLFGGAATLIPGLPFDRGGIAYGTGLMPKATIAPERVLSPRQTELFERMV
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               TLAANLAGSLGGGFNALIEVGQALAANLAGGFSLPTLAAELSAALQASFG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      AALERNPRAATGSTTIVDVGGITVAGGPEAGERVRAGLMELMH-------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ASFPEVVAAFTGGLNGLVQAGQTLAANLAGSLGGGFNALVEVGQALAANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               VGGFSLPALAAQISAALQASFGASFPEAVAAFTGGLNGLVQAGQSLAANL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AGSLGGGFNALIEVGQALAANLVGGFSLPTLAAQISAALQASLGTSFPEL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               MAGFTGGFTGLLQTGQSLAGNLVGSFGGGLDALIQTGQNVAANLVGAFNA
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               PALLAGLNSGLNGLVQTGASLAGNLAGAFGAGLPELATQLSAALSASLSG
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               DLSAELSAALTASLANTASGLLSGLAQTGATLAGGIGGGLLGLIGTGETL
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               ASSLAGGVSGLLGTGESLLMIWQNATAEVTGALSDAVVASIGVGLPGLSQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AAVTLSTGIANASVGLTQTGGVIVSALDNAALGITGDISAALANLQLAIQ
MAV_0534|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
Mb3538|M.bovis_AF2122/97            --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MUL_4367|M.ulcerans_Agy99           --------------------------------------------------
TH_4429|M.thermoresistible__bu      --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_2991|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MMAR_2461|M.marinum_M               AALNASFGVQVAA
MAV_0534|M.avium_104                -------------
MLBr_01183|M.leprae_Br4923          -------------
Mb3538|M.bovis_AF2122/97            -------------
Rv3508|M.tuberculosis_H37Rv         -------------
Mflv_5091|M.gilvum_PYR-GCK          -------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------
MUL_4367|M.ulcerans_Agy99           -------------
TH_4429|M.thermoresistible__bu      -------------
MAB_4284c|M.abscessus_ATCC_199      -------------
MSMEG_2991|M.smegmatis_MC2_155      -------------