For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SFVFAEPQYLSAAATDLASIGSTIDTAGSAAALATTGVIPAGLDEVSAGIAALFGAHGQAYQELSARAAL FHDEFVRVLSAGADAYASSEVANAQAVLAAGPGGLFEQVGRVQAGFTANLVSGELAFNQALVANEAAVID AVGGANSLVGGVIYGGFNATNLVVGTGQQFVNTLVGAQIPASLSTSLLLGGQVPGAQIGAGLSGVVQTGQ SLAGSFNAALSGMGTQLSAALSGSLSAGLPDLSSLGVQLGAGLSGDLSAGLPSVSGLVQTGQVLAGSFND AVGGLGSRVAGVLSGAVGGELPDLSGLVQAGAVLMGGVGTALSGLGAQLSAALSGSLGTAVPGLSALIQT GESLAGGFNAALGTLGTQVSGMLSGGLGGGLPGLAALIQTGESLAGGFGTGLTGFMGGVDVLGNLGGELS AVGAQFNAAVAAGLTGDFSGFPVLVDTVSGLPGAVLAQLGQAQNGVLAGFVDGQLAFNQSLVANEVALQQ ALFGTDAALNGAVNHGFNAVNLLVGTGEQAVNAVLGAPTPASFTGSLLVGGSLEGDIPTGGLPGVAHQLL LLNAALGGPALVDASWLSQFGQAQAAFNADVLSGQLAFNESLVTNEMALQQAIFGTDSALNGAVNHAFNM VNFTLGAGQQTVDALLGVPVPADFTGSLLASGSADAFGGVTTGGLLGAVEQKFLMDGAFLSVFGVPIQVT LDGRLPELIGQLTGSASGGVEVGTEVGGEIPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4287 | - | - | 100% (733) | PE-PGRS family protein |
| M. marinum M | MMAR_2461 | - | 8e-66 | 33.21% (828) | PE-PGRS family protein |
| M. marinum M | MMAR_0608 | - | 7e-43 | 33.45% (562) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0287c | PE_PGRS4 | 1e-41 | 30.43% (736) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-09 | 24.22% (669) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 3e-42 | 32.78% (598) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 4e-12 | 36.96% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-16 | 27.63% (456) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_1346 | - | 7e-17 | 43.64% (110) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-10 | 25.00% (672) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3062 | - | 2e-40 | 30.83% (720) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-11 | 26.70% (412) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Rv0746|M.tuberculosis_H37Rv ----------------------------------MSFVLAMPEVLGSAAT
MUL_3062|M.ulcerans_Agy99 ----------------------------------MAFVLAVPDMVAEAAA
Mb0287c|M.bovis_AF2122/97 ----------------------------------MSFVIAAPEVIAAAAT
MLBr_01183|M.leprae_Br4923 ---------------------------------MPLFLNAEPQALTAAAN
MAV_1346|M.avium_104 ---------------------------------MS-FVTTRPEALLAVAS
MMAR_4287|M.marinum_M ---------------------------------MS-FVFAEPQYLSAAAT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------MSIIDFILNLFR
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Rv0746|M.tuberculosis_H37Rv DLAALGSVLGAADAAAAATTTGIVAAAQDEVSAAIAALFSAHGRAYQVAS
MUL_3062|M.ulcerans_Agy99 DLAGVGSVIDAANTAAAGSTTGIVAAAEDEVSAAIAALFSGHGQAYQQIS
Mb0287c|M.bovis_AF2122/97 DLASLESSIAAANAAAAANTTALLAAGADEVSTAVAALFGAHGQAYQALS
MLBr_01183|M.leprae_Br4923 TLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHA
MAV_1346|M.avium_104 MLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSALQAAQFSAYGTWYQQVS
MMAR_4287|M.marinum_M DLASIGSTIDTAGSAAALATTGVIPAGLDEVSAGIAALFGAHGQAYQELS
MAB_4284c|M.abscessus_ATCC_199 DPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQW
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Rv0746|M.tuberculosis_H37Rv --------------------------AQAAAVHAQFVEALSAGAGAYASA
MUL_3062|M.ulcerans_Agy99 --------------------------TRVAEFHAQFERVFAAGVQAYSGA
Mb0287c|M.bovis_AF2122/97 --------------------------AQAQAFHAQFVQALTSGGGAYAAA
MLBr_01183|M.leprae_Br4923 --------------------------SQGATNHQDLIQSLLTSSSAYAGT
MAV_1346|M.avium_104 --------------------------AQAKAIHQTLVQNLDTNADSYGAT
MMAR_4287|M.marinum_M --------------------------ARAALFHDEFVRVLSAGADAYASS
MAB_4284c|M.abscessus_ATCC_199 VN--------------------------TGNPIHDLSGNLQNYYAAQPDG
.
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Rv0746|M.tuberculosis_H37Rv ---------------------------------------EAAGAAVLANP
MUL_3062|M.ulcerans_Agy99 ---------------------------------------EAANASFLQDP
Mb0287c|M.bovis_AF2122/97 ---------------------------------------EAAATSPLLAP
MLBr_01183|M.leprae_Br4923 -----------------------------------------ETAN-----
MAV_1346|M.avium_104 -----------------------------------------EAANRVNTS
MMAR_4287|M.marinum_M -----------------------------------------EVANAQAVL
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------PSILSPSLLSP
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Rv0746|M.tuberculosis_H37Rv A-------------------QSVQQDL-------------LAAVNAQSVA
MUL_3062|M.ulcerans_Agy99 L-------------------QTALN-----------------ATNKPVQD
Mb0287c|M.bovis_AF2122/97 -------------------------------------------INEFFLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 A------------------------------------------AALQGLA
MMAR_4287|M.marinum_M A------------------------------------------AGPGGLF
MAB_4284c|M.abscessus_ATCC_199 R-------------------------------------------DNDFLS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Rv0746|M.tuberculosis_H37Rv LT-----GRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
MUL_3062|M.ulcerans_Agy99 LT-----GRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAAG
Mb0287c|M.bovis_AF2122/97 NT-----GRPLIGNGANGAPG-----TGADGAPGGWLIGNGGAGGSGAAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 PNV-------------------------------------IPNAAPAADP
MMAR_4287|M.marinum_M EQVG----------------------RVQAGFTANLVSGELAFNQALVAN
MAB_4284c|M.abscessus_ATCC_199 HN------------------------------DTDFASHNPIASGNQVMS
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Rv0746|M.tuberculosis_H37Rv S-GLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGE--AGGAGGSGGWLL
MUL_3062|M.ulcerans_Agy99 ---QAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGG--NGGTGGAGGLLF
Mb0287c|M.bovis_AF2122/97 VNGGAGGNGGAGGLIGNGGAGGAGGRA------STG--TGGAGGAAGMLF
MLBr_01183|M.leprae_Br4923 ----HDSL------------------------------------------
MAV_1346|M.avium_104 PPAGTTSLG---TSIGWAQNVGAAASDFITLGEGQFAPVPGAAGIPN---
MMAR_4287|M.marinum_M EAAVIDAVGGANSLVGGVIYGGFNATNLVVGTGQQFVNTLVGAQIPASLS
MAB_4284c|M.abscessus_ATCC_199 PSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASGQ
.
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAG------AAGAAGAAG---------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAG------AAGAAGKAG---------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAG------AAGNGGDGGNGGFGYVLI
Rv0746|M.tuberculosis_H37Rv GTGGVGGVGGLGAGAGGAGGVGGAGG---LLGAGGHGGAGGL--------
MUL_3062|M.ulcerans_Agy99 GPGGVGGAGGASFLTGGTGGDGGAGG---LFGAGGLGGVGGS--------
Mb0287c|M.bovis_AF2122/97 GAAGVGGPGGFAAAFGATGGAGGAGGNGGLFADGGVGGAGGAT-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M TSLLLGGQVPGAQIGAGLSGVVQTGQSLAGSFNAALSGMGTQ--------
MAB_4284c|M.abscessus_ATCC_199 GSTAVNGDVRDSNIINADHGSNVGVD------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------
Mvan_1264|M.vanbaalenii_PYR-1 -----AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------
MSMEG_0868|M.smegmatis_MC2_155 AGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANG
Rv0746|M.tuberculosis_H37Rv -----GAVTGGVGGTGGAGGLLAG-LLAGPGGAGGTGGRGFLN-------
MUL_3062|M.ulcerans_Agy99 -----GNVGG-NGGAGGAGGLLAG-LVGAGGGDGGSGGLGAAGG-DGGNG
Mb0287c|M.bovis_AF2122/97 -----DAGTGGAGGSGGNGGLFG------AGGTGGPGGFGIFGGGAGGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----FNPGLTAATTAGPPAPAAP--------------------------
MMAR_4287|M.marinum_M -----LSAALSGSLSAGLPDLSSLGVQLGAGLSGDLSAGLPSVS------
MAB_4284c|M.abscessus_ATCC_199 -----QSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTN-------
Mflv_5091|M.gilvum_PYR-GCK ------AVGAAGAAG------TVGTAGATGGTG---------------TG
Mvan_1264|M.vanbaalenii_PYR-1 ------AIGTAGVAG------AAGTAGATGGTG---------------VG
MSMEG_0868|M.smegmatis_MC2_155 GTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG
Rv0746|M.tuberculosis_H37Rv ---------------------NGGVGGAGGNAGLLFG-----------AG
MUL_3062|M.ulcerans_Agy99 GRAGLFGGAGGAGGMGATGGHSGGDGGAGGDAGLLFG-----------TG
Mb0287c|M.bovis_AF2122/97 GSGGLFGAGGTGGSGGTSIINVGGNGGAGGDAGMLSLG---------AAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ------------------------------------------------AA
MMAR_4287|M.marinum_M ---------------------------GLVQTGQVLAGSFNDAVGGLGSR
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------------IN
Mflv_5091|M.gilvum_PYR-GCK ANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 GNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVG
MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAG
Rv0746|M.tuberculosis_H37Rv GTGGSGGAGLGGDGGAGG--------------AGGNTGVLFGNAGSGGTG
MUL_3062|M.ulcerans_Agy99 GAGGAGGHAFDGDGGAGG--------------AGGNAGLMFSSGGSGGVG
Mb0287c|M.bovis_AF2122/97 GAGGSGGSSPDGGGGAGG--------------IGGDGGTLFGSGGAGGVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AAGAPVLASMGRGPSIGG---------------LSVPPSWAPGGVAPAAN
MMAR_4287|M.marinum_M VAGVLSGAVGGELPDLSG---------------LVQAGAVLMGGVGTALS
MAB_4284c|M.abscessus_ATCC_199 DSFNTDRSTNIGSGNTTN---------------TEIGSHNQANIGTSTSA
Mflv_5091|M.gilvum_PYR-GCK GVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----
Mvan_1264|M.vanbaalenii_PYR-1 GIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----
MSMEG_0868|M.smegmatis_MC2_155 GMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGG
Rv0746|M.tuberculosis_H37Rv GFGDTDGGAGGAGGDAGWLG-SGGVGGAGGFGETG-----DGGVG-----
MUL_3062|M.ulcerans_Agy99 GAGSIDGGAGGAGGDAGWLG-GGGAGGAGGFGTIS-----DGGAG-----
Mb0287c|M.bovis_AF2122/97 GLGFDAGGAGGAGGKAGLLSGAGGAGGAGGGSFAG-----AGGTG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ATPAQLVGAGFTSAAPDTAPVTAVPGGVPSMAT-----------------
MMAR_4287|M.marinum_M GLGAQLSAALSGSLGTAVPGLSALIQTGESLAGGF---------------
MAB_4284c|M.abscessus_ATCC_199 GGSAAVGGNAGLAGNAGLAGNAGLAGNAGLAGNAG---------------
Mflv_5091|M.gilvum_PYR-GCK --------LQGGKGGDGGAGGKGGDADSMGS------------------A
Mvan_1264|M.vanbaalenii_PYR-1 --------LQGGQGGDGGTGGTGGDATSMGE------------------A
MSMEG_0868|M.smegmatis_MC2_155 KASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAA
Rv0746|M.tuberculosis_H37Rv ----------GAGGKAGLLIGNGGAGGAGGQ-------------------
MUL_3062|M.ulcerans_Agy99 ----------GRGGGGGQLLGNGGAGGAGGQ-------------------
Mb0287c|M.bovis_AF2122/97 ----------GAGGAPG-LVGNAGNGGNGGA-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------AGRGGYGLGAP-------------------
MMAR_4287|M.marinum_M ---------NAALGTLGTQVSGMLSGGLGGG-------------------
MAB_4284c|M.abscessus_ATCC_199 ---------LAGNAGLAGNAGLAGNAGLAGN-------------------
Mflv_5091|M.gilvum_PYR-GCK GATGGKGGNGGNGGRG---GLFG---------------KGGNAGNGAD--
Mvan_1264|M.vanbaalenii_PYR-1 GATGGKGGNGGNGGRG---SLFG---------------RGGNAGNGGN--
MSMEG_0868|M.smegmatis_MC2_155 SANGAVGGNGGFTNIA---AIHGSITDSSATSGHGGAAQGGNGGNGGNGW
Rv0746|M.tuberculosis_H37Rv GAV--TGGTGGAGGDG---VLIG---------------NGGNAGIGGT--
MUL_3062|M.ulcerans_Agy99 GGN--DGGAGGLGGNG---VLIG---------------NGGNGGVGGV--
Mb0287c|M.bovis_AF2122/97 SANG-AGAAGGAGGSG---VLIG---------------NGGNGGSGGT--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----RYGVKPTVMPKPAI--------------------------------
MMAR_4287|M.marinum_M ----LPGLAALIQTGESLAG------------------GFGTGLT-----
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAG----------------------LAGNAGLAGN--
Mflv_5091|M.gilvum_PYR-GCK --------------------GGTGGAGGA----------GGTGG-TGGAG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------GGTGGNGGN----------GGTGG-TGGNG
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPNGPAGTTIDKGKAAGGNGGDGGF----------NGTGGATGGRG
Rv0746|M.tuberculosis_H37Rv --------------------GPTAGDTGA----------GGISGLLLGAD
MUL_3062|M.ulcerans_Agy99 --------------------GETPGGDGG----------GGISGLLLGAD
Mb0287c|M.bovis_AF2122/97 --------------------GAPAGTAGA----------GGLGGQLLGRD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M --------------------GFMGGVDVLGNLGGELSAVGAQFN------
MAB_4284c|M.abscessus_ATCC_199 --------------------AGLAGNAGL---------------------
Mflv_5091|M.gilvum_PYR-GCK GTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG
Rv0746|M.tuberculosis_H37Rv GFNT-----------------PASASPLHTLKQQALAAINAPTQTLTGRP
MUL_3062|M.ulcerans_Agy99 GFNA-----------------PAGSSPVHALQQQALAAINAPVQELTGRP
Mb0287c|M.bovis_AF2122/97 GFNA-----------------PAS-TPLHTLQQQILNAINEPTQALTGRP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M -------------------------AAVAAGLTGDFSGFPVLVDTVSGLP
MAB_4284c|M.abscessus_ATCC_199 ----------------------AGNAGLAGNAGLAGNAGLAGNAGLAGN-
Mflv_5091|M.gilvum_PYR-GCK GTG-GTGGTGGTGGTGGKGG-TGGTGGAGGTG----GDGGTGGTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 GTG-GTGGTGGTGGTGGKGG-TGGTGGDGGTG----GTGGTGGTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 GVSEGEGGTGGHGGDGGRGG-DGALGGNGGTGGVGLGNGGKGGNGGNGGN
Rv0746|M.tuberculosis_H37Rv LIGNGTPGAVGSGATGAPGGWLLGDGGAGGSG----AAGS-GAPGGAGGA
MUL_3062|M.ulcerans_Agy99 LIGNGLPGSAGSGAAGAPGGWLLGDGGAGGSA----AATP-GAAGGAGGA
Mb0287c|M.bovis_AF2122/97 LIGNGANGTPGTGADGGAGGWLFGNGGNGGHG----ATGADGGDGGSGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M GAVLAQLGQAQNGVLAGFVDGQLAFNQSLVANEVALQQALFGTDAALN--
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAAVAGNAAVAG-----NAAVAGNAAVGGV
Mflv_5091|M.gilvum_PYR-GCK G---------GTGGTGGTGGAG-----------DGTGGTGGTGG----TG
Mvan_1264|M.vanbaalenii_PYR-1 G---------GTGGTGGTGGAG-----------DGLGGTGGTGG----TG
MSMEG_0868|M.smegmatis_MC2_155 GGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADG
Rv0746|M.tuberculosis_H37Rv AG--------LWG-TGGAGGAGG--------SSAGGGGAGGAGGAGGWLL
MUL_3062|M.ulcerans_Agy99 AG--------LVG-AGGAGGAGANT----GISNPGFGGAGGAGGAG----
Mb0287c|M.bovis_AF2122/97 GG--------ILSGIGGTGGSGG-------IGTTGQGGTGGTGGAA-LLI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LN------------------------------------TGVSG-------
Mflv_5091|M.gilvum_PYR-GCK GQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG-----
Mvan_1264|M.vanbaalenii_PYR-1 GFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG-----
MSMEG_0868|M.smegmatis_MC2_155 HRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATI
Rv0746|M.tuberculosis_H37Rv GDGGAGGIGG-------------ASTVLGGTGGGGG-VGGLWGAG-----
MUL_3062|M.ulcerans_Agy99 --AGAG----------------------GGVGEAGG-AGGLLGAG-----
Mb0287c|M.bovis_AF2122/97 GSGGTGGSGG-------------FGLDTGGAGGRGGDAGLFLGAA-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M ----------------------------GAVNHGFNAVNLLVGTG-----
MAB_4284c|M.abscessus_ATCC_199 --------------------------AIGGSSHVGGAINESLGGS-----
Mflv_5091|M.gilvum_PYR-GCK ------------------GQGGTGGTGGQGGTGGTGGTGGTG--------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GTGGTGGTGGQGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 VAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGI
Rv0746|M.tuberculosis_H37Rv ------------------GAGGAGGTG---LVGGDGGAGGAG--------
MUL_3062|M.ulcerans_Agy99 ------------------GTGGGGGVAPSLVDGGTGGAGGAG--------
Mb0287c|M.bovis_AF2122/97 ------------------GTGGQAALSQN--FIGAGGTAGAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M ------------------EQAVNAVLGAPTPASFTGSLLVGG--------
MAB_4284c|M.abscessus_ATCC_199 ------------------GSVGGSTAVGGGAHTGVGGGVSTG-------V
Mflv_5091|M.gilvum_PYR-GCK GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGT
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGV
MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGT
Rv0746|M.tuberculosis_H37Rv GTGGLLA-GLIGAGGGHGGTGGLS----TNGDGGVGGAG--GNAGMLAGP
MUL_3062|M.ulcerans_Agy99 GAGGLFG-GIFGAGGGDGGAGGFTG--GIDGAGGVGGAG--GNTGLLGGP
Mb0287c|M.bovis_AF2122/97 GTGGLFANGGAGGFGANGGTGGNG---LLFGAGGTGGAGTLGADGGAGGH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M SLEGDIPTGGLPGVAHQLLLLNAALGGPALVDASWLSQFGQAQAAFNADV
MAB_4284c|M.abscessus_ATCC_199 GVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVGG
Mflv_5091|M.gilvum_PYR-GCK AGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG-----
Mvan_1264|M.vanbaalenii_PYR-1 AGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG-----
MSMEG_0868|M.smegmatis_MC2_155 ASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALV
Rv0746|M.tuberculosis_H37Rv GGAGGAGGD-----GENLDTGGDGGAGGSAGLLFG--SGGAGGAG-----
MUL_3062|M.ulcerans_Agy99 GGSGGSGGDGIAKLGFNVD-GGAGGAGVNGGFLFG--SGGTGGFG-----
Mb0287c|M.bovis_AF2122/97 GGLFGAGGTGGAGGSSGGTFGGNGGSGGNAGLLALGASGGAGGSG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M LSGQLAFNESLVTNEMALQQAIFGTDSALNGAVNHAFNMVNFTLG-----
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSG--SVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGG-----
Mflv_5091|M.gilvum_PYR-GCK -AQGATG-ATGAAGKAGATGAAGAAGAA---GSAG-----------TTGA
Mvan_1264|M.vanbaalenii_PYR-1 -AQGATG-ATGASGAQGSAGSAGSAGVA---GSAG-----------TTGA
MSMEG_0868|M.smegmatis_MC2_155 MAAGTTGVATGNTATGGDGGAATTAGAT---GGAGGFSNIAAIHGAITDS
Rv0746|M.tuberculosis_H37Rv -GFG------FLGGDGGAGGNAGLLLSS---GGAG-----------GFGG
MUL_3062|M.ulcerans_Agy99 -GVGGVGTSTGIGGAGGRGGNAGLLFSD---AGVG-----------GFGG
Mb0287c|M.bovis_AF2122/97 -GSALN--VGGTGGVGGNGGSGGSLFGF---GGAG-----------GTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M AGQQTVDALLGVPVPADFTGSLLASGSADAFG------------------
MAB_4284c|M.abscessus_ATCC_199 -ISESLGGSGSVGGSTAVGGGAHTSAIN----------------------
Mflv_5091|M.gilvum_PYR-GCK QGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAG
Mvan_1264|M.vanbaalenii_PYR-1 QGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPG
MSMEG_0868|M.smegmatis_MC2_155 TAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGG
Rv0746|M.tuberculosis_H37Rv FGTAG--------------------------------------GVGGAGG
MUL_3062|M.ulcerans_Agy99 FGGTGGNAGWLGSGGSGGAGGGSNGDGGAGGTGGSGGQIVGDGGAGGAGG
Mb0287c|M.bovis_AF2122/97 SSGIGSSGGTGGDGG--------------------------TAGVFGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M -------------------------------------------GVTTGGL
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------DALGGSGS
Mflv_5091|M.gilvum_PYR-GCK SGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE----
Mvan_1264|M.vanbaalenii_PYR-1 SEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE----
MSMEG_0868|M.smegmatis_MC2_155 VNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPG
Rv0746|M.tuberculosis_H37Rv NAGWLGFG-GAGGVGG-----------SAG---LIGTGGNGGNGGT----
MUL_3062|M.ulcerans_Agy99 QGDLLAAG-GSGGDGG-----------QGGDAVLIGTGGNGGNGAS----
Mb0287c|M.bovis_AF2122/97 DGGAGGFGTGAGGTGG-----------TGGNAVLIGNGGNGGNG------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M LGAVEQKFLMDGAFLS-----------VFGVPIQVTLDGRLPELIG----
MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGGGAHTSAIN-------------ESMNSSINASHSSSMN----
Mflv_5091|M.gilvum_PYR-GCK ----GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 ----GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
Rv0746|M.tuberculosis_H37Rv ----GANAGSPGTGGAGGLLLGQNGLNGLP--------------------
MUL_3062|M.ulcerans_Agy99 ----GVLAGIGGDGGSRGLLLGEDGVNGEAAPPMTHIVLLGGDFPAAAS-
Mb0287c|M.bovis_AF2122/97 ----GKAGGTPGAGGTSGLIIGENGLNGL---------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4287|M.marinum_M -----QLTGSASGGVEVGTEVGGEIPE-----------------------
MAB_4284c|M.abscessus_ATCC_199 ----ESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-----