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AMNLVHRLCCDSDRWANEVKGQVLPWVLADVDLGDNVLEIGPGYGAFLRVLVDKTPKLTAVEIDPAMARR LQERYGEQARIINGDGTDTGLPAEEFSSVVSFTMLHHVPTTELQDELFAEAYRVLRPGGVFAGSDGIPSL LFSILHFRDTCNPIPPTDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2358 | - | - | 100% (190) | hypothetical protein MMAR_2358 |
| M. marinum M | MMAR_1415 | - | 4e-13 | 33.11% (151) | hypothetical protein MMAR_1415 |
| M. marinum M | MMAR_0244 | - | 9e-07 | 30.00% (110) | methyltransferase/methylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3862c | - | 1e-65 | 62.23% (188) | hypothetical protein Mb3862c |
| M. gilvum PYR-GCK | Mflv_2862 | - | 4e-10 | 38.83% (103) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3832c | - | 1e-65 | 62.23% (188) | hypothetical protein Rv3832c |
| M. leprae Br4923 | MLBr_01723 | - | 1e-07 | 36.45% (107) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_2704 | - | 4e-61 | 62.79% (172) | hypothetical protein MAB_2704 |
| M. avium 104 | MAV_0196 | - | 1e-68 | 63.83% (188) | hypothetical protein MAV_0196 |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 4e-07 | 31.13% (151) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2189 | - | 6e-08 | 35.85% (106) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1534 | - | 1e-109 | 98.94% (189) | hypothetical protein MUL_1534 |
| M. vanbaalenii PYR-1 | Mvan_2318 | - | 9e-42 | 48.57% (175) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2358|M.marinum_M --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu VIRRLMATALTALTTAVLAGCGDAGSWVEAKPAEGWSAQYGDAANSSYTS
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2358|M.marinum_M --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu AAGAEALTLEWSRSVKGELAAQVAVGASGYLAVNAQTPAGCSLMVWEYAN
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2358|M.marinum_M --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu SARQRWCTRLVQGGGRTSPLLDGFDNVYIGQPGAILSFPPTQWIRWRKPV
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2358|M.marinum_M --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 --------------------------------------------------
TH_2189|M.thermoresistible__bu IGMPTTPRILAPGELLVVTHLGQVLLFDAHRGTVTGTPLDLVAGVDPTDS
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2358|M.marinum_M --------------------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0196|M.avium_104 --------------------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_01723|M.leprae_Br4923 ------------------------------------------MTRSTEIS
TH_2189|M.thermoresistible__bu ERGLADCAGARXXXCWPPPRPPSTVTPRARDAARHPTARLPAMTETTEPG
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_2358|M.marinum_M --------------------------------------MAMNLVHRLCCD
MUL_1534|M.ulcerans_Agy99 --------------------------------------MAMNLVHRLCCD
Mb3862c|M.bovis_AF2122/97 --------------------------------------MAMNLLHRRHCS
Rv3832c|M.tuberculosis_H37Rv --------------------------------------MAMNLLHRRHCS
MAV_0196|M.avium_104 -----------------------------------MIAMAMNLLHRHRCS
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 ----------------------------------------MNEAHR-LCG
MLBr_01723|M.leprae_Br4923 AN-------AVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEKWSIS
TH_2189|M.thermoresistible__bu IGSEGAGDLPAPNPHATAEQVEAAMRDSKLAQILYHDWEAESYDDKWSIS
Mflv_2862|M.gilvum_PYR-GCK ----------------------------------------MNMAETALIN
MSMEG_2350|M.smegmatis_MC2_155 -----------------------------MGDPDNALPSALPLTGERTIP
MMAR_2358|M.marinum_M SDR----WANEVKGQVLPWVLAD-VDLGDNVLEIGPGYGAFLRVLVDK--
MUL_1534|M.ulcerans_Agy99 SDR----WANEVKGQVFPWVLAD-VDLGDNALEIGPGYGAFLRVLVDK--
Mb3862c|M.bovis_AF2122/97 SAG----WEKAVANQLLPWALQH-VELGPRTLEIGPGYGATLQALLGL--
Rv3832c|M.tuberculosis_H37Rv SAG----WEKAVANQLLPWALQH-VELGPRTLEIGPGYGATLQALLGL--
MAV_0196|M.avium_104 SAG----WAKEVADELLPWALDG-VELGSRTLEIGPGYGATLSALLDR--
MAB_2704|M.abscessus_ATCC_1997 --M----WARKTESQLLPWALQG-VELGADTLEIGPGYGANLRVLTNR--
Mvan_2318|M.vanbaalenii_PYR-1 SDQ----WRQMIRDVILPWAMGD-HRLGDDVLEVGPGYGATTDVLCTE--
MLBr_01723|M.leprae_Br4923 YDQRCVDYVRHCFDAIVPDELFT-ELPYDCALELGCGTGFFLLNLIQSGV
TH_2189|M.thermoresistible__bu YDQRCVDYARGRFDAIVPDHVQR-ELPYDNALELGCGTGFFLLNLIQSGV
Mflv_2862|M.gilvum_PYR-GCK SAPR--RWLQRVYEVPVLLRFGGRLVPDTQALEIGCGSGYGTQLILERFG
MSMEG_2350|M.smegmatis_MC2_155 GLAEENYWFRRHEVVYQRLAHRC---AGRDVLEAGCGEGYGADLIADV--
: . .** * * * :
MMAR_2358|M.marinum_M TPKLTAVEIDPAMARRLQERYGEQ-----ARIIN--GDGTDTGLPAE--E
MUL_1534|M.ulcerans_Agy99 TPKLTAVEIDPAMARRLQERYGEQ-----ARIIN--GDGTDTGLPAE--E
Mb3862c|M.bovis_AF2122/97 TASLTAVEVDNSMVERLNRRYGQR-----ARIIR--GDGTQTGLPDD--H
Rv3832c|M.tuberculosis_H37Rv TASLTAVEVDNSMVERLNRRYGQR-----ARIIR--GDGTQTGLPDD--H
MAV_0196|M.avium_104 TASLTAVELDPVMADRLQRRYGDR-----ARVIQ--ASGTETGLPAN--H
MAB_2704|M.abscessus_ATCC_1997 TPQLTAVEIDETMATRLQRLYGDR-----ATVMQ--GDGTKLGFDND--R
Mvan_2318|M.vanbaalenii_PYR-1 VARLTAVEIDPDLAAMLIDRFADQP---SVQIVN--GDAAALDYPDG--R
MLBr_01723|M.leprae_Br4923 ARRGSVTDLSPGMVK-IATRNGQSL---GLDINGRVADAEGIPYDDN--T
TH_2189|M.thermoresistible__bu ARRGSVTDLSPGMVR-VATRNGRSL---GLDVDGRVADAEGIPYDDN--T
Mflv_2862|M.gilvum_PYR-GCK AATVDAVDLDPAMIRRAGERLARYGN--RVRLVQGSATDLSTALDAGDGS
MSMEG_2350|M.smegmatis_MC2_155 ARRVIGLDYDEATVAHVRARYPRVDIRH--------GNLAELPLPDA--S
. : . .
MMAR_2358|M.marinum_M FSSVVSFTMLHHVPTTELQDELFAEAYRVLRPGG--VFAGS---------
MUL_1534|M.ulcerans_Agy99 FSSVVSFTMLHHVPTTELQDELFAEAYRVLRPGG--VFAGS---------
Mb3862c|M.bovis_AF2122/97 FTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGG--VFAGS---------
Rv3832c|M.tuberculosis_H37Rv FTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGG--VFAGS---------
MAV_0196|M.avium_104 FTSVVCFTMLHHVPSPQLQDQLFAEALRVLQPGG--TFAGS---------
MAB_2704|M.abscessus_ATCC_1997 FSSVVCFTMLHHVPTADLQDQLFAQAHRVLAPGG--VFAGS---------
Mvan_2318|M.vanbaalenii_PYR-1 FTGAACFTMLHHVEPSQRQDRLFAEIARVLRPGA--VLVAS---------
MLBr_01723|M.leprae_Br4923 FDLVVGHAVLHHIPDVELS---LREVLRVLKPGGRFVFAGEPTDVGNRYA
TH_2189|M.thermoresistible__bu FDLVVGHAVLHHIPDVELS---LREVVRVLRPGGRFVFAGEPTTVGNSYA
Mflv_2862|M.gilvum_PYR-GCK YGAVFDFGIVHHIPDWRNA---VAEVARVLAPGGRFYFDEVT--------
MSMEG_2350|M.smegmatis_MC2_155 VDVVVNFQVIEHLWD---QAQFVSECFRVLRPGGVFLVSTPN--------
. . ::.*: . : *** **. .
MMAR_2358|M.marinum_M -------------------------------DGIPSLLFSILHFRDTCNP
MUL_1534|M.ulcerans_Agy99 -------------------------------DGIPSLLFSILHFRDTCNP
Mb3862c|M.bovis_AF2122/97 -------------------------------DGVPSLPFRLIHIADTYTP
Rv3832c|M.tuberculosis_H37Rv -------------------------------DGVPSLPFRLIHIADTYTP
MAV_0196|M.avium_104 -------------------------------DGVPSWVFRLLHVADTYNP
MAB_2704|M.abscessus_ATCC_1997 -------------------------------DGVHSTFFRLLHIGDTYNP
Mvan_2318|M.vanbaalenii_PYR-1 -------------------------------DSLASEPLQQMHDGDTYNP
MLBr_01723|M.leprae_Br4923 RVFADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEP
TH_2189|M.thermoresistible__bu RALSTLTWHVATTVTRLPGLQGWRRPQAELDESSRAAALEAVVDLHTFEP
Mflv_2862|M.gilvum_PYR-GCK ------------------------------AHALARPSYKRLFDHPTEDR
MSMEG_2350|M.smegmatis_MC2_155 -------------------RITFSPGRDTPLNPFHTRELNAAELTELLET
.
MMAR_2358|M.marinum_M I--PPTDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKV------------
MUL_1534|M.ulcerans_Agy99 I--PPTDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKA------------
Mb3862c|M.bovis_AF2122/97 I--APADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA-----------
Rv3832c|M.tuberculosis_H37Rv I--APADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA-----------
MAV_0196|M.avium_104 I--APKDLPGRLAAAGFADIHADARGGRQRWRAVKPID------------
MAB_2704|M.abscessus_ATCC_1997 V--PTTSLPDRLRAAGFTDIEHHLDGGNQRWRAVKAA-------------
Mvan_2318|M.vanbaalenii_PYR-1 V--DPQTLPGRLEAAGFTDVEVQTN--EFGWSAVAHRA------------
MLBr_01723|M.leprae_Br4923 K--VLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWA
TH_2189|M.thermoresistible__bu S--DLERMARNAGAVEVATASEEFTAAMLGWPVRTFEAAVPPGKLGWNWA
Mflv_2862|M.gilvum_PYR-GCK F--SAEQFSDELAHHGLVVLGSRTRIQGDYLLGVAAKPLPTGCE------
MSMEG_2350|M.smegmatis_MC2_155 AGFEVEDTLGVFHGAGLAELDARHGGSIIEAQVQRAVADAPWDEQLLADV
.
MMAR_2358|M.marinum_M --------------------------------------
MUL_1534|M.ulcerans_Agy99 --------------------------------------
Mb3862c|M.bovis_AF2122/97 --------------------------------------
Rv3832c|M.tuberculosis_H37Rv --------------------------------------
MAV_0196|M.avium_104 --------------------------------------
MAB_2704|M.abscessus_ATCC_1997 --------------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 --------------------------------------
MLBr_01723|M.leprae_Br4923 RFAFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
TH_2189|M.thermoresistible__bu KFAFGSWTALSWVDANVWRRVMPKGWFYNVMVTGVKPS
Mflv_2862|M.gilvum_PYR-GCK --------------------------------------
MSMEG_2350|M.smegmatis_MC2_155 AAVRTDDFDLTPAAERDIDDSLDLVAIAVRP-------