For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AMNLLHRRHCSSAGWEKAVANQLLPWALQHVELGPRTLEIGPGYGATLQALLGLTASLTAVEVDNSMVER LNRRYGQRARIIRGDGTQTGLPDDHFTSVVCFTMLHHVASAQLQDQLFAEAYRVLQPGGVFAGSDGVPSL PFRLIHIADTYTPIAPADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3832c | - | - | 100% (191) | hypothetical protein Rv3832c |
| M. tuberculosis H37Rv | Rv3729 | - | 6e-05 | 30.19% (159) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3862c | - | 1e-109 | 100.00% (191) | hypothetical protein Mb3862c |
| M. gilvum PYR-GCK | Mflv_2862 | - | 4e-07 | 33.33% (105) | methyltransferase type 11 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2704 | - | 3e-59 | 62.79% (172) | hypothetical protein MAB_2704 |
| M. marinum M | MMAR_2358 | - | 2e-65 | 62.23% (188) | hypothetical protein MMAR_2358 |
| M. avium 104 | MAV_0196 | - | 3e-81 | 75.66% (189) | hypothetical protein MAV_0196 |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 2e-07 | 29.53% (149) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2193 | - | 1e-05 | 29.46% (129) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1534 | - | 2e-65 | 61.58% (190) | hypothetical protein MUL_1534 |
| M. vanbaalenii PYR-1 | Mvan_2318 | - | 1e-39 | 46.43% (168) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3832c|M.tuberculosis_H37Rv -----------------MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVE
Mb3862c|M.bovis_AF2122/97 -----------------MAMNLLHRRHCSSAGWEKAVANQLLPWALQHVE
MAV_0196|M.avium_104 --------------MIAMAMNLLHRHRCSSAGWAKEVADELLPWALDGVE
MAB_2704|M.abscessus_ATCC_1997 -------------------------------MWARKTESQLLPWALQGVE
MMAR_2358|M.marinum_M -----------------MAMNLVHRLCCDSDRWANEVKGQVLPWVLADVD
MUL_1534|M.ulcerans_Agy99 -----------------MAMNLVHRLCCDSDRWANEVKGQVFPWVLADVD
Mvan_2318|M.vanbaalenii_PYR-1 -------------------MNEAHR-LCGSDQWRQMIRDVILPWAMGDHR
MSMEG_2350|M.smegmatis_MC2_155 ------MGDPDNALPSALPLTGERTIPGLAEENYWFRRHEVVYQRLAHRC
TH_2193|M.thermoresistible__bu MSAFSTAGSDADGPISVLPLTGERTVPGLERENYWFRRHEVVYQRLAHRC
Mflv_2862|M.gilvum_PYR-GCK -----------------MNMAETALINSAPRRWLQRVYEVPVLLRFGGRL
. :
Rv3832c|M.tuberculosis_H37Rv LG-PRTLEIGPGYGATLQALLG--LTASLTAVEVDNSMVERLNRRYGQR-
Mb3862c|M.bovis_AF2122/97 LG-PRTLEIGPGYGATLQALLG--LTASLTAVEVDNSMVERLNRRYGQR-
MAV_0196|M.avium_104 LG-SRTLEIGPGYGATLSALLD--RTASLTAVELDPVMADRLQRRYGDR-
MAB_2704|M.abscessus_ATCC_1997 LG-ADTLEIGPGYGANLRVLTN--RTPQLTAVEIDETMATRLQRLYGDR-
MMAR_2358|M.marinum_M LG-DNVLEIGPGYGAFLRVLVD--KTPKLTAVEIDPAMARRLQERYGEQ-
MUL_1534|M.ulcerans_Agy99 LG-DNALEIGPGYGAFLRVLVD--KTPKLTAVEIDPAMARRLQERYGEQ-
Mvan_2318|M.vanbaalenii_PYR-1 LG-DDVLEVGPGYGATTDVLCT--EVARLTAVEIDPDLAAMLIDRFADQP
MSMEG_2350|M.smegmatis_MC2_155 AG-RDVLEAGCGEGYGADLIAD--VARRVIGLDYDEATVAHVRARYPRV-
TH_2193|M.thermoresistible__bu AG-RVVLEAGCGEGYGADLLAE--VAAHVIGLDYDAATVAHVRARYPRV-
Mflv_2862|M.gilvum_PYR-GCK VPDTQALEIGCGSGYGTQLILERFGAATVDAVDLDPAMIRRAGERLARYG
.** * * * : . : .:: *
Rv3832c|M.tuberculosis_H37Rv --ARIIRGDGTQTG----LPDDHFTSVVCFTMLHHVASAQLQDQLFAEAY
Mb3862c|M.bovis_AF2122/97 --ARIIRGDGTQTG----LPDDHFTSVVCFTMLHHVASAQLQDQLFAEAY
MAV_0196|M.avium_104 --ARVIQASGTETG----LPANHFTSVVCFTMLHHVPSPQLQDQLFAEAL
MAB_2704|M.abscessus_ATCC_1997 --ATVMQGDGTKLG----FDNDRFSSVVCFTMLHHVPTADLQDQLFAQAH
MMAR_2358|M.marinum_M --ARIINGDGTDTG----LPAEEFSSVVSFTMLHHVPTTELQDELFAEAY
MUL_1534|M.ulcerans_Agy99 --ARIINGDGTDTG----LPAEEFSSVVSFTMLHHVPTTELQDELFAEAY
Mvan_2318|M.vanbaalenii_PYR-1 -SVQIVNGDAAALD----YPDGRFTGAACFTMLHHVEPSQRQDRLFAEIA
MSMEG_2350|M.smegmatis_MC2_155 ---DIRHGNLAELP----LPDASVDVVVNFQVIEHLWD---QAQFVSECF
TH_2193|M.thermoresistible__bu ---DIRHGNLVDLP----LADASVDVVVNFQVIEHLWD---QEKFIAECL
Mflv_2862|M.gilvum_PYR-GCK NRVRLVQGSATDLSTALDAGDGSYGAVFDFGIVHHIPD---WRNAVAEVA
: ... . . * ::.*: . .::
Rv3832c|M.tuberculosis_H37Rv RVLQPGGVFAGSDG------------VPSLPFRLIHIADTYTPIAP----
Mb3862c|M.bovis_AF2122/97 RVLQPGGVFAGSDG------------VPSLPFRLIHIADTYTPIAP----
MAV_0196|M.avium_104 RVLQPGGTFAGSDG------------VPSWVFRLLHVADTYNPIAP----
MAB_2704|M.abscessus_ATCC_1997 RVLAPGGVFAGSDG------------VHSTFFRLLHIGDTYNPVPT----
MMAR_2358|M.marinum_M RVLRPGGVFAGSDG------------IPSLLFSILHFRDTCNPIPP----
MUL_1534|M.ulcerans_Agy99 RVLRPGGVFAGSDG------------IPSLLFSILHFRDTCNPIPP----
Mvan_2318|M.vanbaalenii_PYR-1 RVLRPGAVLVASDS------------LASEPLQQMHDGDTYNPVDP----
MSMEG_2350|M.smegmatis_MC2_155 RVLRPGGVFLVSTPNRITFSPGRDTPLNPFHTRELNAAELTELLETAGFE
TH_2193|M.thermoresistible__bu RVLRPGGQLLVSTPNRITFTPGSDTPVNPFHTRELNAAELTELLTDGGFG
Mflv_2862|M.gilvum_PYR-GCK RVLAPGGRFYFDEVT--------AHALARPSYKRLFDHPTEDRFSA----
*** **. : . : : .
Rv3832c|M.tuberculosis_H37Rv -ADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA---------------
Mb3862c|M.bovis_AF2122/97 -ADLPGRLRAVGFTDIHVDVAGARLRWRATKPVAA---------------
MAV_0196|M.avium_104 -KDLPGRLAAAGFADIHADARGGRQRWRAVKPID----------------
MAB_2704|M.abscessus_ATCC_1997 -TSLPDRLRAAGFTDIEHHLDGGNQRWRAVKAA-----------------
MMAR_2358|M.marinum_M -TDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKV----------------
MUL_1534|M.ulcerans_Agy99 -TDLPDRLRAAGFHDVEVEVQAGRQRWRAQKPKA----------------
Mvan_2318|M.vanbaalenii_PYR-1 -QTLPGRLEAAGFTDVEVQTN--EFGWSAVAHRA----------------
MSMEG_2350|M.smegmatis_MC2_155 VEDTLGVFHGAGLAELDARHGGSIIEAQVQRAVADAPWDEQLLADVAAVR
TH_2193|M.thermoresistible__bu LSAMYGVFHGPRLAELDARHGGSIIDAQISRALADEPWPAELLADVASVR
Mflv_2862|M.gilvum_PYR-GCK -EQFSDELAHHGLVVLGSRTRIQGDYLLGVAAKPLPTGCE----------
. : : :
Rv3832c|M.tuberculosis_H37Rv ----------------------------------
Mb3862c|M.bovis_AF2122/97 ----------------------------------
MAV_0196|M.avium_104 ----------------------------------
MAB_2704|M.abscessus_ATCC_1997 ----------------------------------
MMAR_2358|M.marinum_M ----------------------------------
MUL_1534|M.ulcerans_Agy99 ----------------------------------
Mvan_2318|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_2350|M.smegmatis_MC2_155 TDDFDLTPAAERD-------IDDSLDLVAIAVRP
TH_2193|M.thermoresistible__bu TEDFDLIRCDEDDRDRDGHNIDDSLDLVAIAVRP
Mflv_2862|M.gilvum_PYR-GCK ----------------------------------