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AKSHVTPVAVIGMACRLPKGIDSPEKFWTALLRGDDLITEIPADRWDADEYYDPEPGVPDHSVSRWGGFL DDVAGFDPEFFGISEREAIAIDPQHRLLLQTSWEAVEHAGMPPMSLSGSLTGVFVGMCHDDYAFVTDDAG ALGDAYAFTGTAFSMASGRVSYALGLRGPAMTVDTACSSSLLAVHMACRSLDGGESELALAGGCMLMLEP DVFSSASAQGMLSPTGRCRTFDASADGFVRSEGCAMLVLKRLPDAVRDGDRVLAVLRGSATNQDGRTDNI STPSPDAQVAAYRAALAVAGVDADTVGMIEAHGTGTPVGDPIEFSSLAQVYGSNGNPCAVGSAKSSVGHT EAAAGAVGIIKAVLSLQHGLVPPMVHHTRLPDELAEIDSALFVPQAITPWPEGNDRTPRRAAVSSYGMSG SNVHVILEQAPEPAVCRNGAAGLGDALLFTVSASSTEALRQTADRLADWVDNHEISPSDLAYTLARRRSH QPVRAGLVAGNRTELAHRLRETAAGDTPYPAAVGHDDLGPVWVFSGQGSQWATMGADLLANEPVFAATVA ELEPLIAAESGFSVTEAMTAMEPVTGIDRVQPTLFAIQVALAQTMRSYGVHPGAVIGHSLGEVAAAVVAG ALLLADGVKVICRRSRLCTRLAGSGAMASVELPAARVREDLVRHRAKDVVVAVVASPQSTVIGGATDTVR ELVAAWGEREVMAREVAVDVASHTPQVEPILGELSELLADVEPLAPQLPYYSATSFDPRERPRCDARYWV DNLRHAVRFSAAVRAALDDGYRVFGELSPHPLLTRAVEQTAASLDIPAAALPAMRRNQPLPHGLRGLVAD LHSAGAAVDFATLYPDGQLVDAPLPVWANRRLLLATADARRHGCANSVAAHPLLGAHVDLLEEPERHAWQ SEIGTATLPWLGDHQVNSVAALPGAAYCEMALAAANTVFGNPSEVGDIGFHEMLLLDDQTAAGAVALVEA PGIASFAVDTVRGGEKVRRSTALLRAVERDSQPAGYDIEALLAAHACRLDGDELREWFAKTGIHYGPAFT GLAAAHVCERGSDAVLAEISLPGSMRTQQAGYLVHPALLDACFQSVLAHPVVREMGNGGLLLPLGVRRLR SHASTRNARFCYTRVTACGHDAEADIDVLDEHGTVLLAVRGLLMGTGLSELADQDRLMSRHLLGTEWQQR ELPQPQAPNPESWLLVGISETADRLTTRLAEALKSLGTDCITTSWHLQADHITDAERFRDQLRDHRFAGV VVMTGTGCSSPVTSDYVRHVVRVVRELPEIMGEAPRLFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAE YPHLHTTHVDVDEHSGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDTEGMRLQ IRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVSFGRYNSPDGQMPQLGTDFAGVVTAVGPD VTDHQVGDRVGGMSPHGCWATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVLI HSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIRADTDGYGVDIVLNS LTGAAQRAGLELLAWGGRFVEIGKRDIYGDTKMGLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQH TAEGVLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVPVLRADGSYIITGGLG GLGLFLAEKMATAGAGRIVLSSRSAPSQKALETIELIRSIGSDVVVECGDIAQPATAARLVANATATNLP LRGVLHAAAVVEDATLANITDELLDRDWAPKVYGAWHLHQATTDQPLDWFCSFSSAAAMLGSPGQGAYAA ANSWLDAFTHWRHNQNQPATAIAWGPWAEIGRAIALAESSDAAIAPDEGAYAFQTLLRHNRTYTGYTPIL GTPWIANLARRSRFAEAFRYDGVQRSERSQLRAELAELPLDEWPTRLRRLISEQVSLILRRTIDPDRPLT DYGLDSLGNLELRTRIETETGIRISSTDITTVRGLADHLCKKLTPAEDAPATM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2344 | pks5_1 | - | 100% (2084) | polyketide synthase, Pks5_1 |
| M. marinum M | MMAR_2340 | pks5 | 0.0 | 76.20% (2092) | polyketide synthase Pks5 |
| M. marinum M | MMAR_1767 | mas | 0.0 | 65.38% (2097) | multifunctional mycocerosic acid synthase membrane-associated |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1554c | pks5 | 0.0 | 68.51% (2102) | polyketide synthase pks5 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 34.30% (2175) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1527c | pks5 | 0.0 | 68.51% (2102) | polyketide synthase pks5 |
| M. leprae Br4923 | MLBr_00139 | mas | 0.0 | 63.07% (2112) | putative mycocerosic synthase |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 61.46% (2086) | polyketide synthase Pks5 |
| M. avium 104 | MAV_2370 | - | 0.0 | 65.62% (2100) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 62.81% (2100) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 67.71% (1815) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 65.28% (2097) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_1003 | - | 0.0 | 34.97% (2179) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------MGSAAHQGESAHR-FAIVGYAGRFPGARDAESFWEL
Mvan_1003|M.vanbaalenii_PYR-1 MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDV
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPF
Mvan_1003|M.vanbaalenii_PYR-1 LRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAGFVEDVAGFDAPF
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATH
Mvan_1003|M.vanbaalenii_PYR-1 FGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLSTH
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1 DYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACS
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK SSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRC
Mvan_1003|M.vanbaalenii_PYR-1 SSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRC
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK KTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASG
Mvan_1003|M.vanbaalenii_PYR-1 KTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAG
Mvan_1003|M.vanbaalenii_PYR-1 GLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AALGPGREPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHL
Mvan_1003|M.vanbaalenii_PYR-1 AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAH
Mvan_1003|M.vanbaalenii_PYR-1 NFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGISSFGFSGTNAH
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VILEEAPLAAEP--AQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVA
Mvan_1003|M.vanbaalenii_PYR-1 VLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPDALAATAHRLRTWLAA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPGL
Mvan_1003|M.vanbaalenii_PYR-1 NPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPGL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGM
Mvan_1003|M.vanbaalenii_PYR-1 ARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVADV
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGF
Mvan_1003|M.vanbaalenii_PYR-1 LERPLLDVVFDAD------GGEALRHTSYAQPALYAVEMGLARLWQSWGI
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAV
Mvan_1003|M.vanbaalenii_PYR-1 EPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAAV
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAGLVADGVRC
Mvan_1003|M.vanbaalenii_PYR-1 FAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVRC
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRSV
Mvan_1003|M.vanbaalenii_PYR-1 DWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRHA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWP
Mvan_1003|M.vanbaalenii_PYR-1 RLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTWP
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLD
Mvan_1003|M.vanbaalenii_PYR-1 GTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLLD
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LPTYPFEHRQYWFSDSREPVAAAPQRGARTETVRLLEDGRIEELAALLGG
Mvan_1003|M.vanbaalenii_PYR-1 LPTYPFQHRAYWFPQGQ--ARTAPTDPVHTETVRFLDEERIDELAALLDG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAAD
Mvan_1003|M.vanbaalenii_PYR-1 PTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPGAARPTTE
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDA
Mvan_1003|M.vanbaalenii_PYR-1 ATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALR-A
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQL
Mvan_1003|M.vanbaalenii_PYR-1 TVSQPRPHILYLAALEEPG-GSAAETLGWMQHRVLAAARRLFQLAATAGA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGG
Mvan_1003|M.vanbaalenii_PYR-1 RAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTT
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPL
Mvan_1003|M.vanbaalenii_PYR-1 GDAEEWSALIDHIVAAPT---SEDQIAVRGREIHVARLTRCAEKANAAAL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK HLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIE
Mvan_1003|M.vanbaalenii_PYR-1 ELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASDTVRQRID
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTT
Mvan_1003|M.vanbaalenii_PYR-1 AMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGTS
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFG
Mvan_1003|M.vanbaalenii_PYR-1 PLRTLDDAEMDRVFAGKVWGAVYLCEEVADMGLDFFLATSSIASVWGSHG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRG
Mvan_1003|M.vanbaalenii_PYR-1 QTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IKTLSPADALAGLSDAVISAAPHPVVARVDWSRFLPLYQQAGRRGFLAEL
Mvan_1003|M.vanbaalenii_PYR-1 VKTLAPADALAGMADVIAASTAHAVVARIDWATFLPVYQLQRRRAFLSQL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEV
Mvan_1003|M.vanbaalenii_PYR-1 EREVPDVPDASAPAP--SGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEV
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2344|M.marinum_M --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_00139|M.leprae_Br4923 --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRL
Mvan_1003|M.vanbaalenii_PYR-1 TRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHL
Mb1554c|M.bovis_AF2122/97 ------------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDS
Rv1527c|M.tuberculosis_H37Rv ------------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDS
MMAR_2344|M.marinum_M --------------------------MAKSHVTPVAVIGMACRLPKGIDS
MAV_2370|M.avium_104 -------------------------------MVPVAVIGMACRLPGAVDS
MSMEG_4727|M.smegmatis_MC2_155 --------------------------MTQNCVAPVAIIGMACRLPGAINS
TH_4621|M.thermoresistible__bu -----------------------VNIVGDTPVNAVAVIGMACRLPGGIDS
MLBr_00139|M.leprae_Br4923 ---------------------------METSVTPIAVIGMGCRLPGGINS
MUL_2010|M.ulcerans_Agy99 ---------------------------MQKSATPVAIIGMGCRLPGGVDS
MAB_3148c|M.abscessus_ATCC_199 ---------------------------------------MGCRLPGGIES
Mflv_0405|M.gilvum_PYR-GCK SDAADYLLGDVLGLTEAATAPKAATVVSTAADEPIAIVAVSCRFPG-APN
Mvan_1003|M.vanbaalenii_PYR-1 SDAAEYVLGDVLGLSEHTVA-QPDTPSTVRTDDPIAIVGMACRFPG-ADD
:.**:* .
Mb1554c|M.bovis_AF2122/97 PDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNV
Rv1527c|M.tuberculosis_H37Rv PDRLWEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNV
MMAR_2344|M.marinum_M PEKFWTALLRGDDLITEIPADRWDADEYYDPEPGVPDHSVSRWGGFLDDV
MAV_2370|M.avium_104 PERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDV
MSMEG_4727|M.smegmatis_MC2_155 PQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDP
TH_4621|M.thermoresistible__bu PQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDV
MLBr_00139|M.leprae_Br4923 PDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDV
MUL_2010|M.ulcerans_Agy99 PEKLWESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDV
MAB_3148c|M.abscessus_ATCC_199 PEQFWQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDV
Mflv_0405|M.gilvum_PYR-GCK PEAFWDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHI
Mvan_1003|M.vanbaalenii_PYR-1 TDAFWSVLAEGADLIREIPDDRFDINEFYDPDPEAAGKIYSRYGGFLDGV
.: :* * * : : *:* *:* :::**:. ...: ::*.:::
Mb1554c|M.bovis_AF2122/97 GDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTGV
Rv1527c|M.tuberculosis_H37Rv GDFDPEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMA-SRTGV
MMAR_2344|M.marinum_M AGFDPEFFGISEREAIAIDPQHRLLLQTSWEAVEHAGMPPMSLSGSLTGV
MAV_2370|M.avium_104 AGFDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGV
MSMEG_4727|M.smegmatis_MC2_155 AAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGV
TH_4621|M.thermoresistible__bu AGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGV
MLBr_00139|M.leprae_Br4923 AGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAV
MUL_2010|M.ulcerans_Agy99 AGFDAEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGV
MAB_3148c|M.abscessus_ATCC_199 GGFDADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGV
Mflv_0405|M.gilvum_PYR-GCK DEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGV
Mvan_1003|M.vanbaalenii_PYR-1 DGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGV
**.:**.: :** ::**:* :*:* *:.:*:.* : * :.*
Mb1554c|M.bovis_AF2122/97 FVGLVHTDY-ILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAIT
Rv1527c|M.tuberculosis_H37Rv FVGLVHTDY-ILVHADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAIT
MMAR_2344|M.marinum_M FVGMCHDDY-AFVTDDAGALGDAYAFTGTAFSMASGRVSYALGLRGPAMT
MAV_2370|M.avium_104 FIGLTHGDY-QLLAADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALT
MSMEG_4727|M.smegmatis_MC2_155 FMGLTHNDY-AHLAADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAIT
TH_4621|M.thermoresistible__bu FVGLSHDDY-ALLTSDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVT
MLBr_00139|M.leprae_Br4923 FTGLTHEDY-LVLTTAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMT
MUL_2010|M.ulcerans_Agy99 FVGLSHEDY-LVRSVLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMT
MAB_3148c|M.abscessus_ATCC_199 FVGVTHNDY-QLVAADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLT
Mflv_0405|M.gilvum_PYR-GCK FVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVA
Mvan_1003|M.vanbaalenii_PYR-1 YVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVA
: *: :* . :* :**::. :*:.**:::
Mb1554c|M.bovis_AF2122/97 VDTACSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGML
Rv1527c|M.tuberculosis_H37Rv VDTACSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGML
MMAR_2344|M.marinum_M VDTACSSSLLAVHMACRSLDGGESELALAGGCMLMLEPDVFSSASAQGML
MAV_2370|M.avium_104 VDTACSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGML
MSMEG_4727|M.smegmatis_MC2_155 VDTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGML
TH_4621|M.thermoresistible__bu VDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGML
MLBr_00139|M.leprae_Br4923 FDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGML
MUL_2010|M.ulcerans_Agy99 VDTACSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGML
MAB_3148c|M.abscessus_ATCC_199 VDAGCAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRML
Mflv_0405|M.gilvum_PYR-GCK VDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARML
Mvan_1003|M.vanbaalenii_PYR-1 VDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARML
.*:.*::.* ::* . :.* *:.::.**** : *.* . * **
Mb1554c|M.bovis_AF2122/97 SATGRCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAAN
Rv1527c|M.tuberculosis_H37Rv SATGRCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAAN
MMAR_2344|M.marinum_M SPTGRCRTFDASADGFVRSEGCAMLVLKRLPDAVRDGDRVLAVLRGSATN
MAV_2370|M.avium_104 SPTGRCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAAN
MSMEG_4727|M.smegmatis_MC2_155 SPTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATN
TH_4621|M.thermoresistible__bu SPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAAN
MLBr_00139|M.leprae_Br4923 SSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATN
MUL_2010|M.ulcerans_Agy99 SPTGRCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAAN
MAB_3148c|M.abscessus_ATCC_199 SPTGRCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASN
Mflv_0405|M.gilvum_PYR-GCK SPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVN
Mvan_1003|M.vanbaalenii_PYR-1 SPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVN
*. *:*::* ***:* .**. :: **** **: *.:*: *:: *:* *
Mb1554c|M.bovis_AF2122/97 QDGHTVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPI
Rv1527c|M.tuberculosis_H37Rv QDGHTVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPI
MMAR_2344|M.marinum_M QDGRTDNISTPSPDAQVAAYRAALAVAGVDADTVGMIEAHGTGTPVGDPI
MAV_2370|M.avium_104 QDGHTVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPI
MSMEG_4727|M.smegmatis_MC2_155 QDGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPL
TH_4621|M.thermoresistible__bu QDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPI
MLBr_00139|M.leprae_Br4923 QDGGTETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPI
MUL_2010|M.ulcerans_Agy99 QDGRSETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPI
MAB_3148c|M.abscessus_ATCC_199 QDGRTVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPI
Mflv_0405|M.gilvum_PYR-GCK QDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPI
Mvan_1003|M.vanbaalenii_PYR-1 QDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPI
*** : *. ** .* **: :. :*.**.**.:***:
Mb1554c|M.bovis_AF2122/97 EYASLAEVYGNDG----PCALASVKTNFGHTQSAAGALGLMKAVLALQHG
Rv1527c|M.tuberculosis_H37Rv EYASLAEVYGNDG----PCALASVKTNFGHTQSAAGALGLMKAVLALQHG
MMAR_2344|M.marinum_M EFSSLAQVYGSNGN---PCAVGSAKSSVGHTEAAAGAVGIIKAVLSLQHG
MAV_2370|M.avium_104 EYASLAEVYGIDG----PCALASVKTNFGHAQAASGALGMMKAILALQHG
MSMEG_4727|M.smegmatis_MC2_155 EFSSLAEVYGTDG----PCALGSIKTNFGHTQSAAGALGVMKAVLALQHN
TH_4621|M.thermoresistible__bu EYNSLTQVYGKTG----PCALTSVKTNFGHAESAAGALGMMKAILALQHG
MLBr_00139|M.leprae_Br4923 EYRSLARVYGAG-T---PCALGSAKSNMGHSTASAGTVGLIKAILSLRNG
MUL_2010|M.ulcerans_Agy99 EYRSLAQVYGSGGS---RCMLGSVKTNIGHSESAAGTVGLIKATLSLGHG
MAB_3148c|M.abscessus_ATCC_199 EYTGLAQVYGVDG----PCAVGSVKTNFGHTMSAAGALGLMKIVLAVEHG
Mflv_0405|M.gilvum_PYR-GCK EVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHE
Mvan_1003|M.vanbaalenii_PYR-1 EVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHE
* . . . : * *:..** :::*. *::* *:: :
Mb1554c|M.bovis_AF2122/97 VVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMT
Rv1527c|M.tuberculosis_H37Rv VVPQNLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMT
MMAR_2344|M.marinum_M LVPPMVHHTRLPDELAEIDSALFVPQAITPWPEGNDRTPRRAAVSSYGMS
MAV_2370|M.avium_104 VVPRNLHFTQLPDDLARIDTKLFVPQQTTPWVS-NGGHPRRAAVSSYGLS
MSMEG_4727|M.smegmatis_MC2_155 VIPQNLHFTRLPDQMAEIETGLFVPETITPWPV-REGQPRRAAVSAYGLS
TH_4621|M.thermoresistible__bu VVPQNLHFTRLPDEMAAIETNLFVPQATTLWPV-REGCPRRAAVSSYGMS
MLBr_00139|M.leprae_Br4923 LVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMS
MUL_2010|M.ulcerans_Agy99 VVPPMVHHTRLPDELAEIETGLYVPHEITPWPED--QGPRRIAVSSFGMS
MAB_3148c|M.abscessus_ATCC_199 VVPPNLHFTGIPDKLAPVKTNLFVPQTVIPWPG-KAQGPRRAGVSAYGMS
Mflv_0405|M.gilvum_PYR-GCK TLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQP--NGRPRRAGVSSFGFT
Mvan_1003|M.vanbaalenii_PYR-1 MLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRA--DGRPRRAGVSSFGFS
:* :*. . .:. : * * *:* .**::*::
Mb1554c|M.bovis_AF2122/97 GTNVHAIVEQAPVPAPESGAPGDTPATPG--------IDGALLFALSASS
Rv1527c|M.tuberculosis_H37Rv GTNVHAIVEQAPVPAPESGAPGDTPATPG--------IDGALLFALSASS
MMAR_2344|M.marinum_M GSNVHVILEQAPEPAVCRNG------AAG--------LGDALLFTVSASS
MAV_2370|M.avium_104 GTNVHAILEQAPEPAPETVAP--EGIS----------AESPLLFPLSSTS
MSMEG_4727|M.smegmatis_MC2_155 GTNVHAVLEQAPE-SPAETAA--EAISPK--------AGNALVFPVSASS
TH_4621|M.thermoresistible__bu GTNVHAVLEQAPE--PVQRPE--ESADTD--------AAGPLVFALSSTS
MLBr_00139|M.leprae_Br4923 GTNVHVIVEEAPSEACAPDVPETSPGTGDA-------TVGRQLFMLSSTS
MUL_2010|M.ulcerans_Agy99 GTNVHAILEEPPTPAPARDQASAEPG-----------MASPLLFALSSTS
MAB_3148c|M.abscessus_ATCC_199 GSNVHAVVEQAPPVESSTPPAVESP------------LGSQLIFPVSSTS
Mflv_0405|M.gilvum_PYR-GCK GTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARS
Mvan_1003|M.vanbaalenii_PYR-1 GTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARS
*:*.*.::*:.* :: :*: *
Mb1554c|M.bovis_AF2122/97 QDALRQTAARLADWVDAQGP------ELAPADLAYTLARRRGHRPVRTAV
Rv1527c|M.tuberculosis_H37Rv QDALRQTAARLADWVDAQGP------ELAPADLAYTLARRRGHRPVRTAV
MMAR_2344|M.marinum_M TEALRQTADRLADWVDN--H------EISPSDLAYTLARRRSHQPVRAGL
MAV_2370|M.avium_104 ADELRRTAGRLADWVHAHGD-------LALPDLAYTLARRRVHRPVRTAV
MSMEG_4727|M.smegmatis_MC2_155 ADALRSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAV
TH_4621|M.thermoresistible__bu AEELRRTAGRLAEWVEAHTD------EVVPADLAYTLARRRAHRPVRTTV
MLBr_00139|M.leprae_Br4923 IAALRETARQLATWV---EEHQD---SVVLSDLAYTLARGRAHRPVRTAV
MUL_2010|M.ulcerans_Agy99 ADGLRQTARELAEWVGSRADSAD---STEAVDLAYTLARRRAHRPVRTAV
MAB_3148c|M.abscessus_ATCC_199 AEELRRTAARLADWVAERPE-------VAPGDVGYTLARRRAHRSVRTAV
Mflv_0405|M.gilvum_PYR-GCK PEALVALAQRYETWLTAHPE-------ADLADVCRTAGTGRSHFEHRAAL
Mvan_1003|M.vanbaalenii_PYR-1 PEALTALARRYESWLTAHPD-------ADIADVCYTAGAGRSHFEHRAAL
* * . *: *: * . * . *: :
Mb1554c|M.bovis_AF2122/97 LAATTAELTEALREVATGETPYPPAVGQDDRGP--VWVFSGQGSQWAGMG
Rv1527c|M.tuberculosis_H37Rv LAATTAELTEALREVATGEPPYPPAVGQDDRGP--VWVFSGQGSQWAGMG
MMAR_2344|M.marinum_M VAGNRTELAHRLRETAAGDTPYPAAVGHDDLGP--VWVFSGQGSQWATMG
MAV_2370|M.avium_104 LAGDRAQLIEALREVADGDTPYPAAVGRGDRGP--VWVFSGQGSQWAAMG
MSMEG_4727|M.smegmatis_MC2_155 LAGDRGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMG
TH_4621|M.thermoresistible__bu IADGVEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMG
MLBr_00139|M.leprae_Br4923 VAADLPELVEGLCEIADGDALYDAVVGHGDRGP--VWVFSGQGSQWASMG
MUL_2010|M.ulcerans_Agy99 VAASLPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMG
MAB_3148c|M.abscessus_ATCC_199 VADGADELIDALRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMG
Mflv_0405|M.gilvum_PYR-GCK VVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMA
Mvan_1003|M.vanbaalenii_PYR-1 VVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKTAWLFTGQGSQYPGMA
:. * * . . * .*:*:*****:. *.
Mb1554c|M.bovis_AF2122/97 ADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGI--------
Rv1527c|M.tuberculosis_H37Rv ADLLATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTGI--------
MMAR_2344|M.marinum_M ADLLANEPVFAATVAELEPLIAAESGFSVTEAMTAMEPVTGI--------
MAV_2370|M.avium_104 ADLLATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQ--------
MSMEG_4727|M.smegmatis_MC2_155 AELLDREPAFAAAIAELEPLIAAESDFSVTEALTASETVTGI--------
TH_4621|M.thermoresistible__bu AELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGI--------
MLBr_00139|M.leprae_Br4923 VQLLANEPVFAATITKLEPVIAAESSFSVTEAITAPETVTGI--------
MUL_2010|M.ulcerans_Agy99 ADLLANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTGI--------
MAB_3148c|M.abscessus_ATCC_199 AELLGKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTGI--------
Mflv_0405|M.gilvum_PYR-GCK RELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRH
Mvan_1003|M.vanbaalenii_PYR-1 RELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDNGQ----TLRH
:*: * .* :: : .: :.: *
Mb1554c|M.bovis_AF2122/97 -DRVQPTLFAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLE
Rv1527c|M.tuberculosis_H37Rv -DRVQPTLFAMQVALAATMK-SYGVAPGAVIGHSLGESAAAVVAGALCLE
MMAR_2344|M.marinum_M -DRVQPTLFAIQVALAQTMR-SYGVHPGAVIGHSLGEVAAAVVAGALLLA
MAV_2370|M.avium_104 -DRVQPTLFTMQVALAATMK-AHGVRPGAVIGHSLGEAAAAVVAGALSLE
MSMEG_4727|M.smegmatis_MC2_155 -DRVQPTIFAVQVALAAAMR-SHGVVPGAVIGHSMGEVAASVVSGALSLE
TH_4621|M.thermoresistible__bu -DRVQPTLFAIQVALAATMQ-SYGVRPGAVIGHSLGEVAAAVVAGALSLE
MLBr_00139|M.leprae_Br4923 -DKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLE
MUL_2010|M.ulcerans_Agy99 -DKVQPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLE
MAB_3148c|M.abscessus_ATCC_199 -DRVQPTLFAMQVSLAATLA-SYGVRPGAVIGHSMGEVAAAVVSEALSLE
Mflv_0405|M.gilvum_PYR-GCK TSFAQPALFAVEMGLARLWQ-SWGIVPDVVLGHSVGQYAAACVAGVFSLE
Mvan_1003|M.vanbaalenii_PYR-1 TSYAQPALFAIEMGLARLWQ-ARGIEPDVVLGHSVGQYAAACVAGVFGLE
. .**::*::::.** : *: *..*:***:*: **: *: : *
Mb1554c|M.bovis_AF2122/97 DGVRVICRRSALMTRIAGAGAMASVELPAQQVLSELMARGVNDAVVAVVA
Rv1527c|M.tuberculosis_H37Rv DGVRVICRRSALMTRIAGAGAMASVELPAQQVLSELMARGVNDAVVAVVA
MMAR_2344|M.marinum_M DGVKVICRRSRLCTRLAGSGAMASVELPAARVREDLVRHRAKDVVVAVVA
MAV_2370|M.avium_104 DGARVICRRSRLMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVVA
MSMEG_4727|M.smegmatis_MC2_155 DGVKVICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVA
TH_4621|M.thermoresistible__bu DGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIA
MLBr_00139|M.leprae_Br4923 DAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVA
MUL_2010|M.ulcerans_Agy99 DGARVISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVA
MAB_3148c|M.abscessus_ATCC_199 DGVKVICRRSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVA
Mflv_0405|M.gilvum_PYR-GCK DGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVGAYNGP
Mvan_1003|M.vanbaalenii_PYR-1 DGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQVSVAAYNGP
*..:::. * * :. * : * * . .. .
Mb1554c|M.bovis_AF2122/97 SPQSTVIGGATQTVRDLVAAWEQRDVLAREVAVDVASHSPQVDPILDELA
Rv1527c|M.tuberculosis_H37Rv SPQSTVIGGATQTVRDLVAAWEQRDVLAREVAVDVASHSPQVDPILDELA
MMAR_2344|M.marinum_M SPQSTVIGGATDTVRELVAAWGEREVMAREVAVDVASHTPQVEPILGELS
MAV_2370|M.avium_104 SPQSTVIAGAAPTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLT
MSMEG_4727|M.smegmatis_MC2_155 SPQSTVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLI
TH_4621|M.thermoresistible__bu SPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELE
MLBr_00139|M.leprae_Br4923 SPQSTVIGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLA
MUL_2010|M.ulcerans_Agy99 SPQSTVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLA
MAB_3148c|M.abscessus_ATCC_199 SPQSTVVGGATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLA
Mflv_0405|M.gilvum_PYR-GCK N---TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFE
Mvan_1003|M.vanbaalenii_PYR-1 N---TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFE
. **:.*. :.::: : : .. * *: ::*:: ::
Mb1554c|M.bovis_AF2122/97 EALAEISPLQPEIPYYS-ATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQ
Rv1527c|M.tuberculosis_H37Rv EALAEISPLQPEIPYYS-ATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQ
MMAR_2344|M.marinum_M ELLADVEPLAPQLPYYS-ATSFDPRERPRCDARYWVDNLRHAVRFSAAVR
MAV_2370|M.avium_104 DALAEISPRPPEVPYYS-ATLFDPREQPVCDARYWANNMRRMVRFATAVQ
MSMEG_4727|M.smegmatis_MC2_155 EALADLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQ
TH_4621|M.thermoresistible__bu EILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQ
MLBr_00139|M.leprae_Br4923 AALADIAPMTPKVPYYS-ATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQ
MUL_2010|M.ulcerans_Agy99 TALADIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQ
MAB_3148c|M.abscessus_ATCC_199 DALEDLTPRTPVVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQ
Mflv_0405|M.gilvum_PYR-GCK SYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVR
Mvan_1003|M.vanbaalenii_PYR-1 SCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESVR
: * * . . :. ** : *. *:*: :*:
Mb1554c|M.bovis_AF2122/97 AALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHGL
Rv1527c|M.tuberculosis_H37Rv AALEDGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHGL
MMAR_2344|M.marinum_M AALDDGYRVFGELSPHPLLTRAVEQTAASLDIPAAALPAMRRNQPLPHGL
MAV_2370|M.avium_104 AALEDGYRVFAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGL
MSMEG_4727|M.smegmatis_MC2_155 AALEDGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGL
TH_4621|M.thermoresistible__bu AALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGV
MLBr_00139|M.leprae_Br4923 AAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGL
MUL_2010|M.ulcerans_Agy99 AALEDGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGL
MAB_3148c|M.abscessus_ATCC_199 AALDDGYRVFGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGL
Mflv_0405|M.gilvum_PYR-GCK TVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQI
Mvan_1003|M.vanbaalenii_PYR-1 TLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGPDARRQL
: * *: *: *:*.* . : . .:..:*: :
Mb1554c|M.bovis_AF2122/97 RALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT-TRRIAH
Rv1527c|M.tuberculosis_H37Rv RALAGDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT-TRRIAH
MMAR_2344|M.marinum_M RGLVADLHSAGAAVDFATLYPDGQLVDAPLPVWANRRLLLATADARRHGC
MAV_2370|M.avium_104 RGFVADLHNAGAAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGLESPTH
MSMEG_4727|M.smegmatis_MC2_155 LGFVADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDR-ELESSAP
TH_4621|M.thermoresistible__bu RTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTR
MLBr_00139|M.leprae_Br4923 RGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQ
MUL_2010|M.ulcerans_Agy99 RGLLTDVHSAGAAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQ
MAB_3148c|M.abscessus_ATCC_199 RDFVGDLYTAGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGH
Mflv_0405|M.gilvum_PYR-GCK ADALAAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDG
Mvan_1003|M.vanbaalenii_PYR-1 AEAVAAAYIAGHRLDFTGHDGGPHRRLPLPTYPFQHRSYWPKTAGIRSDG
. .* **: . .
Mb1554c|M.bovis_AF2122/97 AN-TVAVHPLLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALP
Rv1527c|M.tuberculosis_H37Rv AN-TVAVHPLLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALP
MMAR_2344|M.marinum_M AN-SVAAHPLLGAHVDLLEEPERHAWQSEIGTATLPWLGDHQVNSVAALP
MAV_2370|M.avium_104 GGCTVAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLP
MSMEG_4727|M.smegmatis_MC2_155 GVPSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLP
TH_4621|M.thermoresistible__bu GGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALP
MLBr_00139|M.leprae_Br4923 GACTVTVHPLLGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALP
MUL_2010|M.ulcerans_Agy99 GACSVTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALP
MAB_3148c|M.abscessus_ATCC_199 GTHTVAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYP
Mflv_0405|M.gilvum_PYR-GCK RVGASAGSGILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVP
Mvan_1003|M.vanbaalenii_PYR-1 ----SSGSGLLGSAQDLASG--DIVHTSRLSVKTQPWLSDHVIYGTVVVP
: :**. * . :.. .*:.** : ... *
Mb1554c|M.bovis_AF2122/97 GAAYCEMALAAARAVLG-EASEVRDIRFEQMLLLDDETPIGVTATVE---
Rv1527c|M.tuberculosis_H37Rv GAAYCEMALAAARAVLG-EASEVRDIRFEQMLLLDDETPIGVTATVE---
MMAR_2344|M.marinum_M GAAYCEMALAAANTVFG-NPSEVGDIGFHEMLLLDDQTAAGAVALVE---
MAV_2370|M.avium_104 GAAYCEMALAAARSVLG-ATAEVRDIRFEQALLLDEQTTVDASASVS---
MSMEG_4727|M.smegmatis_MC2_155 GAAYCEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVT---
TH_4621|M.thermoresistible__bu GAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAV---
MLBr_00139|M.leprae_Br4923 GAAYCEMALAAAVEVFG-EAAEVRAIAFEQMLLLAAETPIDAIASVD---
MUL_2010|M.ulcerans_Agy99 GAAYCEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLD---
MAB_3148c|M.abscessus_ATCC_199 GAAYCEMALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAK---
Mflv_0405|M.gilvum_PYR-GCK GATYAAMALAAVGTPAH-----AKDVFFYEPIILPEKSSREVQLTVHPSV
Mvan_1003|M.vanbaalenii_PYR-1 GATYAAMALAAMPTPAR-----VQEVFFYEPIILGDKDSREVQLMLHRTD
**:*. ***:* . : * : : * .
Mb1554c|M.bovis_AF2122/97 APGVVPLTVETSHDGRYTRQLAAVLHVVREADDAP---DQPPQKNIAELL
Rv1527c|M.tuberculosis_H37Rv APGVVPLTVETSHDGRYTRQLAAVLHVVREADDAP---DQPPQKNIAELL
MMAR_2344|M.marinum_M APGIASFAVDTVRGGEKVRRSTALLRAVERDS-------QPAGYDIEALL
MAV_2370|M.avium_104 SPGVLHFTVQSHQGGEQARHASAVLGAATD-E-------QPAAHDLSALL
MSMEG_4727|M.smegmatis_MC2_155 APGTAEFGVETHQSGDRTQRATAVLRGDVDAE-------RPAAHSIDALL
TH_4621|M.thermoresistible__bu EPGTLEFAVETAKDGEHERRATAVLGAADDTE-------PPQAHDIDALL
MLBr_00139|M.leprae_Br4923 APGVINFVVQANQDGEKMRNATATLHAAEDDC-------PPPAYDIAALL
MUL_2010|M.ulcerans_Agy99 SPGAANFVVQTHVDGETTRHATAALRASDDES-------VPPAYDIAALL
MAB_3148c|M.abscessus_ATCC_199 SADILEFVVETHDEGDVVKRATAVLGNGGDVD-------MPIAYDLSALR
Mflv_0405|M.gilvum_PYR-GCK DGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEA
Mvan_1003|M.vanbaalenii_PYR-1 DADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD--AAPDAAADPVDNA
: *.: * : .
Mb1554c|M.bovis_AF2122/97 ASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAEVNLP
Rv1527c|M.tuberculosis_H37Rv ASHPHKVDGAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGDTVLAEVNLP
MMAR_2344|M.marinum_M AAHACRLDGDELREWFAKTGIHYGPAFTGLAAAHVCERGSDAVLAEISLP
MAV_2370|M.avium_104 TAHPHDDDGDEVRRRMDRRGVQYGPAFAGLGAVHSGDETG-TVLAEVALP
MSMEG_4727|M.smegmatis_MC2_155 AAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALP
TH_4621|M.thermoresistible__bu AEHPTRIEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLP
MLBr_00139|M.leprae_Br4923 EAHPNSVNGTDLRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVALP
MUL_2010|M.ulcerans_Agy99 AAHPVSVNGAELREAFVERGIQHGPAFSGLAIARTAETEGGTVLAEVALP
MAB_3148c|M.abscessus_ATCC_199 AEHPHRESGDDLRASFDERGVQYGPAFQGLAAAYRGDETVRSVLAEVTLP
Mflv_0405|M.gilvum_PYR-GCK IERLNRMRPQELFETFADLELAWGPTWS--GSLKSLWLGEGEAIGDILVG
Mvan_1003|M.vanbaalenii_PYR-1 IERLTRTRPQQLFDAFADNDLAWGPAWC--SSLRSLWVGTGEAVGDIAVG
: :: : *.:: .:. : :
Mb1554c|M.bovis_AF2122/97 GPLRSQVKAYGVHPVLLDACFQSVAAHPAVQGMAD-GGLLLPLGVRRLRS
Rv1527c|M.tuberculosis_H37Rv GPLRSQVKAYGVHPVLLDACFQSVAAHPAVQGMAD-GGLLLPLGVRRLRS
MMAR_2344|M.marinum_M GSMRTQQAGYLVHPALLDACFQSVLAHPVVREMGN-GGLLLPLGVRRLRS
MAV_2370|M.avium_104 RQIRSQQAAYGAHPALLDACFQSVEAHPAVRALGD-GALGLVLGIRRLRA
MSMEG_4727|M.smegmatis_MC2_155 GPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIAS-GML-LPLGVRRLRA
TH_4621|M.thermoresistible__bu GQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGS-GLL-LPLGVRRLQA
MLBr_00139|M.leprae_Br4923 ASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAGLLLPLGVRSLRV
MUL_2010|M.ulcerans_Agy99 ASIRFQQGAYGVHPALLDACFQSVAAGVKSTGGG---GLLLPLGVRSLRA
MAB_3148c|M.abscessus_ATCC_199 RDVRAQQGSYIVHPALLDACFQSVIALPDVQEASK-DALPLPKGVRSLHA
Mflv_0405|M.gilvum_PYR-GCK AELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQV
Mvan_1003|M.vanbaalenii_PYR-1 AELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRV
: **.*:* * . . * :* :
Mb1554c|M.bovis_AF2122/97 YGSARHARYCCTTVTACG-----VGVEADLDVLDEHGAVVLAVRGLQLGT
Rv1527c|M.tuberculosis_H37Rv YGSARHARYCCTTVTACG-----VGVEADLDVLDEHGAVVLAVRGLQLGT
MMAR_2344|M.marinum_M HASTRNARFCYTRVTACG-----HDAEADIDVLDEHGTVLLAVRGLLMGT
MAV_2370|M.avium_104 YGAARNAHYCYTRVTKADT----SGVEADIDVLDEHGAVLLAVQGLRVGT
MSMEG_4727|M.smegmatis_MC2_155 YGSTRNVRYCLSRIVKADS----FGVEADLELLDADGTVLLSAMGLQLGT
TH_4621|M.thermoresistible__bu FGPTRGARYCYARVTDADG----SKAEADLDVLDEHGNVLLRVQGLLMGG
MLBr_00139|M.leprae_Br4923 YRPTRNARYCYTRLTKIEP----RGGEADLDVLDEHGAVLLAVRGLHMGT
MUL_2010|M.ulcerans_Agy99 YGPTRNAQYCYTRVTKADA----NGGEADLELLDEQGCVLLAVRGLRLGT
MAB_3148c|M.abscessus_ATCC_199 YESARATQYCYTRVTKVVG----NEVEADIDLLDETGSVLIAVRGFRFGT
Mflv_0405|M.gilvum_PYR-GCK SLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKR
Mvan_1003|M.vanbaalenii_PYR-1 EVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKR
: : *:: ** * : : .
Mb1554c|M.bovis_AF2122/97 GASQASER--ARVLGERLLSIEWHERELPENS---HAEPGAWLLIST---
Rv1527c|M.tuberculosis_H37Rv GASQASER--ARVLGERLLSIEWHERELPENS---HAEPGAWLLIST---
MMAR_2344|M.marinum_M GLSELADQ--DRLMSRHLLGTEWQQRELPQPQ---APNPESWLLVGI---
MAV_2370|M.avium_104 SASESGTR--DRVLTERLLNIEWRQRELPEPE---HADAASWLLIGT---
MSMEG_4727|M.smegmatis_MC2_155 GNSDKAEE--ERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAG--
TH_4621|M.thermoresistible__bu AAADGDDR--DRVLGERLLTIEWQRRDLPEAD----SAAGKWLLVST---
MLBr_00139|M.leprae_Br4923 GTTERGEL--DRQLSERLLTIGWQQRTLPESV---HVEPGSWLLIDTFNA
MUL_2010|M.ulcerans_Agy99 GTSESGER--DRVLSERLLTLEWQQRQLPEVL---DEETGSWLLIS---A
MAB_3148c|M.abscessus_ATCC_199 GSSDDEQR--DQLLNNRLLAIEWQQQRLPESVS---GAPRRWLLVST---
Mflv_0405|M.gilvum_PYR-GCK APREALLRGLGGDATRLLYTLGWHEVPVPESGDGAA-PQGTWLIGGFDEL
Mvan_1003|M.vanbaalenii_PYR-1 APREALLRGLGADATRLIYRVGWRETSPPVRDDGALGPSSTWLVAGLDAL
. : . : *:. * **:
Mb1554c|M.bovis_AF2122/97 CDATDLVAAQLTDALKV---HDAQCTTMSWPQRADHAAQAARLRDQLGTG
Rv1527c|M.tuberculosis_H37Rv CDATDLVAAQLTDALKV---HDAQCTTMSWPQRADHAAQAARLRDQLGTG
MMAR_2344|M.marinum_M SETADRLTTRLAEALKS---LGTDCITTSWHLQADHITDAERFRDQLRDH
MAV_2370|M.avium_104 TATADVLASTLADTLKN---HGAQCTTMAWPQQADHTAHAEQLRNQWRGD
MSMEG_4727|M.smegmatis_MC2_155 DDDENPRAAGVVSALIG---AGMPTTTMAWSHDADHDAQAAALTARLDEQ
TH_4621|M.thermoresistible__bu SATADVSATRLSDALKQ---AGAESTSMCWPQQADHADNVDRFRAGIADG
MLBr_00139|M.leprae_Br4923 SAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPVVSRERLGRQLRGR
MUL_2010|M.ulcerans_Agy99 SDGEDLMATTLADALKS---QGAECASMVWSAQDDLAGGIEKLGAQLRAR
MAB_3148c|M.abscessus_ATCC_199 GESVDPWAAELIDSLKVR---ESEVSLIQWRPNTDRVAALKLLYDQLESG
Mflv_0405|M.gilvum_PYR-GCK AVSVPGCIPA--------------------DRTNPESLRQLLTDAHGRGL
Mvan_1003|M.vanbaalenii_PYR-1 ADDVPGSIRIGFDRIWDP----DRDGRVVLDPADDEHWRRLFALADERRA
Mb1554c|M.bovis_AF2122/97 GFTGVFVLTAPQTGD----PDAESPVRGGELVKHVVRIAREIPEITAQEP
Rv1527c|M.tuberculosis_H37Rv GFTGVFVLTAPQTGD----PDAESPVRGGELVKHVVRIAREIPEITAQEP
MMAR_2344|M.marinum_M RFAGVVVMTG--TG-------CSSPVTS-DYVRHVVRVVRELPEIMGEAP
MAV_2370|M.avium_104 GFTGVVVLTG-PKNGDNDQESALLSR---DHVQHLVRIARELTDLPGEPP
MSMEG_4727|M.smegmatis_MC2_155 PLAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAVGEPP
TH_4621|M.thermoresistible__bu -VTGVVVLTG-PKNGNPDD---AAARRGSDYVRHLVRITRELAEIDGDAP
MLBr_00139|M.leprae_Br4923 D--GVVILCGPRAGA----PDEQSLLAAREQVRHLVRIIRELAELEGELP
MUL_2010|M.ulcerans_Agy99 TNKGVVIVCGPRSGD----ADEQSLLQGREQVRHLVRITRGLAELEGELP
MAB_3148c|M.abscessus_ATCC_199 TFDGVLVVTAPGSEG----GADRVVLQGADQVRHLVRITRELVDLPGEPP
Mflv_0405|M.gilvum_PYR-GCK PFSGVVWRAA-RSDGD--ESDAEVAARLEAEIAELLGAVHTVQGGEVKLP
Mvan_1003|M.vanbaalenii_PYR-1 PVAGVVLGVTGRARPE--EPSADFAARLEAQIRDVLGAVHSLSALGAKPA
** : .:: : : . .
Mb1554c|M.bovis_AF2122/97 R-LYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQ
Rv1527c|M.tuberculosis_H37Rv R-LYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQ
MMAR_2344|M.marinum_M R-LFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEH
MAV_2370|M.avium_104 R-LYVVTRNAQTVLPNDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDES
MSMEG_4727|M.smegmatis_MC2_155 R-LYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDS
TH_4621|M.thermoresistible__bu R-LFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADD
MLBr_00139|M.leprae_Br4923 R-LFVVTRQAQIVQSGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEH
MUL_2010|M.ulcerans_Agy99 R-LFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDES
MAB_3148c|M.abscessus_ATCC_199 R-LFVVTRNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRH
Mflv_0405|M.gilvum_PYR-GCK GGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGS
Mvan_1003|M.vanbaalenii_PYR-1 AGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGS
*:::*. : . : :..: *: *. * * * :*
Mb1554c|M.bovis_AF2122/97 TGAESVARQLLAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAE
Rv1527c|M.tuberculosis_H37Rv TGAESVARQLLAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDHAE
MMAR_2344|M.marinum_M SGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDT
MAV_2370|M.avium_104 TDAQALARQLLAGSEEDETAWRDGAWYTARLCPAPLLPEERHTAVANHEC
MSMEG_4727|M.smegmatis_MC2_155 TAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADNAS
TH_4621|M.thermoresistible__bu ADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCER
MLBr_00139|M.leprae_Br4923 TDVERVAQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEH
MUL_2010|M.ulcerans_Agy99 TQAEQLAQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTVVDHER
MAB_3148c|M.abscessus_ATCC_199 TAAQNVAGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRSTVATPNN
Mflv_0405|M.gilvum_PYR-GCK PQAVQALAALLSTPVDE----PELAVRQGKLLASRLLPWSRSGHLTVPRG
Mvan_1003|M.vanbaalenii_PYR-1 EDAGPALARLLGAPGDE----PELALRQGRLLVPRLLPWSRSGQLAIPRG
*:. :: .:* * . :
Mb1554c|M.bovis_AF2122/97 AGMRLQIRTPGDLQTLEFAALDRVPPGPGEIEVAVTASSINFADVLVTFG
Rv1527c|M.tuberculosis_H37Rv AGMRLQIRTPGDLQTLEFAAFDRVPPGPGEIEVAVTASSINFADVLVTFG
MMAR_2344|M.marinum_M EGMRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVSFG
MAV_2370|M.avium_104 DGMRLQIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFG
MSMEG_4727|M.smegmatis_MC2_155 EGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAFG
TH_4621|M.thermoresistible__bu DGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFG
MLBr_00139|M.leprae_Br4923 DGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFG
MUL_2010|M.ulcerans_Agy99 DNMRLQIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIAFG
MAB_3148c|M.abscessus_ATCC_199 EGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVLNVYG
Mflv_0405|M.gilvum_PYR-GCK GDYVLAPTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNVLG
Mvan_1003|M.vanbaalenii_PYR-1 TDYVLAPTERGVLDNLRVSETEVTAPPEGHVQVRVEAAGLNFRDVLNALG
. . * ::.: . : .* * ::* * :.:** *** *
Mb1554c|M.bovis_AF2122/97 RYQTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATFVT
Rv1527c|M.tuberculosis_H37Rv RYQTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATFVT
MMAR_2344|M.marinum_M RYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGCWATFVT
MAV_2370|M.avium_104 RYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLT
MSMEG_4727|M.smegmatis_MC2_155 RCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNFVT
TH_4621|M.thermoresistible__bu RYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVT
MLBr_00139|M.leprae_Br4923 RFPIIDDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLT
MUL_2010|M.ulcerans_Agy99 RYPSLEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSYLT
MAB_3148c|M.abscessus_ATCC_199 RYSSFEGRQ-ELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVV
Mflv_0405|M.gilvum_PYR-GCK LYP---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-AFASRFN
Mvan_1003|M.vanbaalenii_PYR-1 LYP---GDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVG-AFASRVN
. * :: *.*: * .* :*::* * .: . .
Mb1554c|M.bovis_AF2122/97 CDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHSAT
Rv1527c|M.tuberculosis_H37Rv CDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHSAT
MMAR_2344|M.marinum_M CDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVLIHSGT
MAV_2370|M.avium_104 CDARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSAT
MSMEG_4727|M.smegmatis_MC2_155 CEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHSAT
TH_4621|M.thermoresistible__bu CDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSAT
MLBr_00139|M.leprae_Br4923 CDANLAVTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKVLIHSAT
MUL_2010|M.ulcerans_Agy99 CDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHSAT
MAB_3148c|M.abscessus_ATCC_199 VDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGT
Mflv_0405|M.gilvum_PYR-GCK VPGQFLAPIPDGVSAVEAATIPAAALTVRL-SFDWAQVKSGDKVLIHAAS
Mvan_1003|M.vanbaalenii_PYR-1 VPVQFLAPVPEGISAVAAATTPAAVLTAGL-AFDWAALRAGDRVLIHAAS
: . :* :. * : * *. : . : *:::***:.:
Mb1554c|M.bovis_AF2122/97 GGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ
Rv1527c|M.tuberculosis_H37Rv GGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFAEQ
MMAR_2344|M.marinum_M GGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEA
MAV_2370|M.avium_104 GGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADL
MSMEG_4727|M.smegmatis_MC2_155 GGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTAFADQ
TH_4621|M.thermoresistible__bu GGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADE
MLBr_00139|M.leprae_Br4923 GGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQ
MUL_2010|M.ulcerans_Agy99 GGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFADQ
MAB_3148c|M.abscessus_ATCC_199 GGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTDFAEL
Mflv_0405|M.gilvum_PYR-GCK GGVGLAAVQMAQQCGAEVYATAST-FKRATLRKLGVKHVYDSRTTDFAEQ
Mvan_1003|M.vanbaalenii_PYR-1 GGVGLAAVQLARQRGATVFATASG-YKRPMLRAMGVDHVYDSRTTDFADQ
**** **: :*: ** ::***. :* :. *:.******: **:
Mb1554c|M.bovis_AF2122/97 IRRDTAGYGVDIVLNSVTGAAQLAG-LKLLALGGRFIEIGKRDIYSNTRL
Rv1527c|M.tuberculosis_H37Rv IRRDTAGYGVDIVLNSVTGAAQLAG-LKLLALGGRFIEIGKRDIYSNTRL
MMAR_2344|M.marinum_M IRADTDGYGVDIVLNSLTGAAQRAG-LELLAWGGRFVEIGKRDIYGDTKM
MAV_2370|M.avium_104 IRHDTDGYGVDIVLNSVTGAAQRAG-IELLAFGGRFVEIGKRDIYGDTRL
MSMEG_4727|M.smegmatis_MC2_155 IRTDTDGYGVDIVLNSVTGPAQRAG-LELLAFGGRFVEIGKRDIYADTRL
TH_4621|M.thermoresistible__bu IRRDTDGYGVDVVLNSLPGAAQRAG-LELLSFGGRFIEIGKRDIYGDTRL
MLBr_00139|M.leprae_Br4923 IRRDTDGYGVDIVLNSLTGAAQRAG-LELLTFGGRFVEIGKADVYGNTRL
MUL_2010|M.ulcerans_Agy99 IRRDTNGYGVDIVLNSLTGAAQRAG-LELLAFGGRFVEIGKADVYGNTRM
MAB_3148c|M.abscessus_ATCC_199 IRRDTDGYGVDIVLNSLTGAAQRAG-VELLTFGGRFIEIGKRDIYGDTRL
Mflv_0405|M.gilvum_PYR-GCK ILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVE--
Mvan_1003|M.vanbaalenii_PYR-1 ILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIWSPE--
* ** * ***:****:.. . . :. : *** **.* *::
Mb1554c|M.bovis_AF2122/97 ELLPFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTH
Rv1527c|M.tuberculosis_H37Rv ELLPFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEGVLPMPQSTH
MMAR_2344|M.marinum_M GLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEGVLPMPQDTH
MAV_2370|M.avium_104 GLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADGALPMPESTH
MSMEG_4727|M.smegmatis_MC2_155 GLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADGTLPLPEITH
TH_4621|M.thermoresistible__bu GLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTH
MLBr_00139|M.leprae_Br4923 GLFPFRRGLTFYYLDLALMSVTQPDRVRELLATVFNLTADGVLTAPECTH
MUL_2010|M.ulcerans_Agy99 GLYPFRRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEGVLSAPECTH
MAB_3148c|M.abscessus_ATCC_199 GLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEGVLPLPEISP
Mflv_0405|M.gilvum_PYR-GCK QMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEV
Mvan_1003|M.vanbaalenii_PYR-1 QMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFEA
: . * .: : : * : * : * : * .
Mb1554c|M.bovis_AF2122/97 YPLAEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQARVFRSDGSY
Rv1527c|M.tuberculosis_H37Rv YPLAEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQARVFRSDGSY
MMAR_2344|M.marinum_M YPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVPVLRADGSY
MAV_2370|M.avium_104 YPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGAY
MSMEG_4727|M.smegmatis_MC2_155 YPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGDGAY
TH_4621|M.thermoresistible__bu YPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAY
MLBr_00139|M.leprae_Br4923 YPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSY
MUL_2010|M.ulcerans_Agy99 YPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVEVFRGDGSY
MAB_3148c|M.abscessus_ATCC_199 SPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGAY
Mflv_0405|M.gilvum_PYR-GCK YPLTEARAAFRRMQQARHIGKIVVQIPNPLQP------------QPDRSY
Mvan_1003|M.vanbaalenii_PYR-1 YPLAEATTAFRRMQQARHTGKIILQMPKPLQP------------HGDRSY
** :* ::* * * * **:::::* . : * :*
Mb1554c|M.bovis_AF2122/97 IITGGLGGLGLFLAEKMANAG----AGRIVLSSRSQPSQKALETIELVRA
Rv1527c|M.tuberculosis_H37Rv IITGGLGGLGLFLAEKMANAG----AGRIVLSSRSQPSQKALETIELVRA
MMAR_2344|M.marinum_M IITGGLGGLGLFLAEKMATAG----AGRIVLSSRSAPSQKALETIELIRS
MAV_2370|M.avium_104 IVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLERIRQ
MSMEG_4727|M.smegmatis_MC2_155 VITGGLGGLGLFLAERMAAAG----CGRIVVNSRSAPSTRSSEIIELIRA
TH_4621|M.thermoresistible__bu IVTGGMGGLGLYLAGEMAAAG----AGCIVLNGRSAPSGEALRTIEQLRA
MLBr_00139|M.leprae_Br4923 IITGGLGGLGLFFASKLAEAG----CGRIVLTARSQPNPKARQTIERLCA
MUL_2010|M.ulcerans_Agy99 IITGGLGGLGLFFASKMAAAG----CGRIVLTARSQPNPKSRQAIERLRA
MAB_3148c|M.abscessus_ATCC_199 VVTGGLGGLGLFLARKLAAAG----VGRIILNGRSAPKPEALAAIEQIRQ
Mflv_0405|M.gilvum_PYR-GCK LITGGLGAIGLHTAGYLAQLG----AGDIVLTSRRAPDAAAQQAIADIAD
Mvan_1003|M.vanbaalenii_PYR-1 LITGGLGALGLHAAAYLAQLG----AGDIVLTGRRMPDAATERAISEIAE
::***:*.:**. * :* * * *:: .* *. : : :
Mb1554c|M.bovis_AF2122/97 -IGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDATLAN
Rv1527c|M.tuberculosis_H37Rv -IGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAVVEDATLAN
MMAR_2344|M.marinum_M -IGSDVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAVVEDATLAN
MAV_2370|M.avium_104 -MGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATLAN
MSMEG_4727|M.smegmatis_MC2_155 -TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAVVEDATLAN
TH_4621|M.thermoresistible__bu -AGTEVIVECGXXXRG----QPVEVAVPT------ELRHADEHPDRRGAQ
MLBr_00139|M.leprae_Br4923 -AGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN
MUL_2010|M.ulcerans_Agy99 -NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVEDATLSN
MAB_3148c|M.abscessus_ATCC_199 -GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLAN
Mflv_0405|M.gilvum_PYR-GCK RTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQ
Mvan_1003|M.vanbaalenii_PYR-1 RYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQ
: . . : : * * .:
Mb1554c|M.bovis_AF2122/97 ITDELIER-DWAPKAYGAWQLHRATADQP-----LDWFCSFSSAAALVGS
Rv1527c|M.tuberculosis_H37Rv ITDELIER-DWAPKAYGAWQLHRATADQP-----LDWFCSFSSAAALVGS
MMAR_2344|M.marinum_M ITDELLDR-DWAPKVYGAWHLHQATTDQP-----LDWFCSFSSAAAMLGS
MAV_2370|M.avium_104 ITDELIER-DWAAKVYGAWNLHCALQESG-AEQSLDWFCSFSSAAALVGS
MSMEG_4727|M.smegmatis_MC2_155 ITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAALVGS
TH_4621|M.thermoresistible__bu LCDEFARG-EQGAQR----NQHRTDAGEG---------QRDAHPPGAVGH
MLBr_00139|M.leprae_Br4923 ITDELIDR-DWSPKVYGSWNLHCATIGQP-----LDWFCLFSSGAALLGS
MUL_2010|M.ulcerans_Agy99 ITDELIDR-DWSPKVYGSWNLHRASTGQP-----LDWFCLFSSGAALMGS
MAB_3148c|M.abscessus_ATCC_199 ITDELIDRGDWRPKVHGAWNLHEATADQP-----LDWFCSFSSIAALVGS
Mflv_0405|M.gilvum_PYR-GCK QSVERFRT-ALAPKAFGAVHLDRLTRVDD-----LDFFLVSSSVSSLFGS
Mvan_1003|M.vanbaalenii_PYR-1 QSPERFRT-TLAPKAFGAWHLHRLTRDTE-----LEFFIVYSSGSSVLGS
* .: : . : .. .*
Mb1554c|M.bovis_AF2122/97 PGQGAYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGD
Rv1527c|M.tuberculosis_H37Rv PGQGAYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRAIAFAEQTGD
MMAR_2344|M.marinum_M PGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEIGRAIALAESSDA
MAV_2370|M.avium_104 PGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIGRGAALADSADV
MSMEG_4727|M.smegmatis_MC2_155 PGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRGTAMAE-GDN
TH_4621|M.thermoresistible__bu DQPDPGALSDTGLDERGGQFPGVGVQIPVADPGVGIDH-RGAVRVDSGVP
MLBr_00139|M.leprae_Br4923 PGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEI
MUL_2010|M.ulcerans_Agy99 PGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEI
MAB_3148c|M.abscessus_ATCC_199 PGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNAEA
Mflv_0405|M.gilvum_PYR-GCK PGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANI
Mvan_1003|M.vanbaalenii_PYR-1 PGQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARANL
* ::: :* . * . .
Mb1554c|M.bovis_AF2122/97 AIA---PEEGAYAFETLLRHNRAYSGYAPVIGSPWLTAFAQHSP-----F
Rv1527c|M.tuberculosis_H37Rv AIA---PEEGAYAFETLLRHNRAYSGYAPVIGSPWLTAFAQHSP-----F
MMAR_2344|M.marinum_M AIA---PDEGAYAFQTLLRHNRTYTGYTPILGTPWIANLARRSR-----F
MAV_2370|M.avium_104 AIT---PDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQRSP-----F
MSMEG_4727|M.smegmatis_MC2_155 AIA---PDEGAYAFEAILRHDRVYNGYAPVLGASWLTAFAQRSP-----F
TH_4621|M.thermoresistible__bu AQQ---GVDGEVVRHRTLSSVRSGR-------SSRWTAPGSRCG-----S
MLBr_00139|M.leprae_Br4923 MIT---PDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSP-----W
MUL_2010|M.ulcerans_Agy99 MIA---PDEGMYAFEQMLRHARTYTGYIPIIGAPWLADLVRRSP-----W
MAB_3148c|M.abscessus_ATCC_199 AIL---PDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVERSP-----F
Mflv_0405|M.gilvum_PYR-GCK SAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPIL
Mvan_1003|M.vanbaalenii_PYR-1 GAQGLIPLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLLGATRPPIL
: .
Mb1554c|M.bovis_AF2122/97 AEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVGLILRRTID
Rv1527c|M.tuberculosis_H37Rv AEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVGLILRRTID
MMAR_2344|M.marinum_M AEAFRYDGVQRSERSQLRAELAELPLDEWPTRLRRLISEQVSLILRRTID
MAV_2370|M.avium_104 AEAFRANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVSLILRRNVD
MSMEG_4727|M.smegmatis_MC2_155 AELFLADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVGLLLRRTVD
TH_4621|M.thermoresistible__bu GRRYGG--ESCRRTTGPAAGAAARRGR-----------------TRRRRR
MLBr_00139|M.leprae_Br4923 AEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVILRRTID
MUL_2010|M.ulcerans_Agy99 AEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQASVILRRTVD
MAB_3148c|M.abscessus_ATCC_199 AQAFRDAGQNQTETNKFLDELRALPREEWPTRLRKLVAEQVGLVLRRSID
Mflv_0405|M.gilvum_PYR-GCK DLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQP
Mvan_1003|M.vanbaalenii_PYR-1 DHVLPSAVAAGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLAQP
Mb1554c|M.bovis_AF2122/97 TDRL--LSEYGLDSLSSQELRARVEAETG--IRISATEIN--TTVRGLAD
Rv1527c|M.tuberculosis_H37Rv TDRL--LSEYGLDSLSSQELRARVEAETG--IRISATEIN--TTVRGLAD
MMAR_2344|M.marinum_M PDRP--LTDYGLDSLGNLELRTRIETETG--IRISSTDI---TTVRGLAD
MAV_2370|M.avium_104 PDRP--LPEYGLDSLGGLELLTRIQTETG--IRVSPADIAAIGTIRGLAD
MSMEG_4727|M.smegmatis_MC2_155 PDRP--LSEYGLDSLGHLELRTRIETETG--VRVSAMDMT---TIRGLAQ
TH_4621|M.thermoresistible__bu PRRP--PPPP-----------DRVRHRAG--PAHGPVRR-----------
MLBr_00139|M.leprae_Br4923 ADRS--FIEYGLDSLGMLEMRTHIESETG--IRLTPKVIATNNTARALAQ
MUL_2010|M.ulcerans_Agy99 ADRP--FVEYGLDSLGMLEMRTHIETETG--VRLSPKVIASHNTARALSQ
MAB_3148c|M.abscessus_ATCC_199 PDRS--LPDYGLDSLGNLEIRTRIQADTG--VRIGPADVS---TVRSLAA
Mflv_0405|M.gilvum_PYR-GCK PAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAE
Mvan_1003|M.vanbaalenii_PYR-1 PAATGRFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIGALAE
. :: * .
Mb1554c|M.bovis_AF2122/97 LMCDKLAADRDAPAPA----------------------
Rv1527c|M.tuberculosis_H37Rv LMCDKLAADRDAPAPA----------------------
MMAR_2344|M.marinum_M HLCKKLTPAEDAPATM----------------------
MAV_2370|M.avium_104 LLRDKLTPAGAAQAERV---------------------
MSMEG_4727|M.smegmatis_MC2_155 RLCEMLDTDDAVSAPS----------------------
TH_4621|M.thermoresistible__bu --------------------------------------
MLBr_00139|M.leprae_Br4923 YLADTLAEEEGVAAPAAMVSPETP--------------
MUL_2010|M.ulcerans_Agy99 HLADTLAEEEAQPAAS----------------------
MAB_3148c|M.abscessus_ATCC_199 HIYDRLAEQESEVASS----------------------
Mflv_0405|M.gilvum_PYR-GCK YLVAQLPDAETPQAAPQSESEPGPDVTE----------
Mvan_1003|M.vanbaalenii_PYR-1 YLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQTS