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TPVAVIGMACRLPGGIGSPEELWEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNVGD FDPEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVFVGLNHGDYQFVHVDANTFDGP YGNTGTNSCFASGRISYAMRLHGPAVTVDTACSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFAS GSAQNMLSPTGHCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQDGHTVNIATPSV EAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIEFESLARVYGIDRPCALTSAKPNFGHMQAGAGV LGLMKAILALQHGVIPPNIHFSRLPDEMAQIKSGLFVPQEITQWPTNGEQTRTAAVSSYGISGTNVHAIL EQAPETATHDAEPVSPAIEGALIFPLSATSADGLRQTAKRLADWVDAQGPELATSDLAYTLARRRGHRPV RTAVLADNVSELSAGLHEIADDETPYQAAVGRDDRGPVWVFSGQGSQWKAMGADLLANEPVFAATVAELE PLIAAESGFSVTEAMTAIETVTGIDRVQPTIFTMQVALAATMKSYGVRPGAIIGHSLGESAAAVAAGALS LEDGAKVICRRSRLMTRISGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQSTVIGGATDTVRELV AAWEQREVMAREVAVDVASHSPQVDPILDDLYDVLADLEPLTPEVPYYSATLFDPREEPYCDGSYWVDNL RHTVRFGAAVQAALEDGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGLLADLHS AGAAVDFSVLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGSSVVVHPLLGSHVLLPEEPERHVWQSD VGTEALPWLADHQIHSAPALPGAAYCEMALVAARTILGDAAEVRDVRFEQMLLLDDETPLSAVGSVKSPG IVDFVVETFQDGGAVRRGGAVLHAVEDDDQLPAYDIPALLAEHSRTEDGEELRARFDEHGVQYGPAFTGL GNAHIADGAVSSVVAEVALPGAMRSQQRAYAIHPALLDACFQAVGAHPDVQVAGNGGLMLPLGVRQIRAY ASTRNAHYCYARVTSVDTSAVEADLDVLDEHGTVLVAVRGLQLGTGVSEEGNRDRVLNERLLTIEWQQRE LPEVDAAEAGAWLLISTSDGADMLAAELTDALKLHSAQCATTSWHENAADHAASAERLRNQLNAGGFHNA VILLKPDSGDRDENSGVEGVECVRHVVRVVRELPEIMGEAPRLFVVTRGAQTVLGGESANLEQAGLRGLL RVIGAEYPHLHTTHVDVDEHSGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEHDT EGMRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVSFGRYNSPDGQMPQLGTDFAGVV TAVGPDVTDHQVGDRVGGMSPHGCWATFVTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRA GDKVLIHSGTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFAEAIRADTDGYGV DIVLNSLTGAAQRAGLELLAWGGRFVEIGKRDIYGDTKMGLFPFRRNLSFYGVDLGMLSITHPRLIRELL TTVYQHTAEGVLPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVPVLRADGSYI ITGGLGGLGLFLAEKMATAGAGRIVLSSRSAPSQKALETIELIRSIGSDVVVECGDIAQPATAARLVANA TATNLPLRGVLHAAAVVEDATLANITDELLDRDWAPKVYGAWHLHQATTDQPLDWFCSFSSAAAMLGSPG QGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEIGRAIALAESSDAAIAPDEGAYAFQTLLRHNRTYT GYAPIIGAPWVTAFAERSKFAEAFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMVAEQVSLILRRTID PDRQLSEYGLDSLGNLELRTRVQSETGIRISSTDITTVRGLADHLFAQLAPEEAAASSQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2340 | pks5 | - | 100% (2090) | polyketide synthase Pks5 |
| M. marinum M | MMAR_2344 | pks5_1 | 0.0 | 76.20% (2092) | polyketide synthase, Pks5_1 |
| M. marinum M | MMAR_1767 | mas | 0.0 | 67.18% (2093) | multifunctional mycocerosic acid synthase membrane-associated |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1554c | pks5 | 0.0 | 73.38% (2096) | polyketide synthase pks5 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 32.82% (2160) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1527c | pks5 | 0.0 | 73.38% (2096) | polyketide synthase pks5 |
| M. leprae Br4923 | MLBr_01229 | pks3 | 0.0 | 64.57% (2111) | mycocerosic acid synthase (polyketide synthase) |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 62.58% (2082) | polyketide synthase Pks5 |
| M. avium 104 | MAV_2370 | - | 0.0 | 68.82% (2101) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 65.32% (2108) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 68.90% (1804) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2010 | mas | 0.0 | 66.99% (2093) | multifunctional mycocerosic acid synthase membrane-associated |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 33.03% (2165) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
Mvan_0269|M.vanbaalenii_PYR-1 MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1 WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
Mvan_0269|M.vanbaalenii_PYR-1 RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mvan_0269|M.vanbaalenii_PYR-1 EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1 GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
Mvan_0269|M.vanbaalenii_PYR-1 CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
Mvan_0269|M.vanbaalenii_PYR-1 DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1 GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP-LAAEPAQ
Mvan_0269|M.vanbaalenii_PYR-1 VEVVKETIPWER---DGGPRIAGVSSFGFAGTNAHVILEEAPEQAAAPGP
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAGTA
Mvan_0269|M.vanbaalenii_PYR-1 VQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAGAG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1 RAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWLFT
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVL
Mvan_0269|M.vanbaalenii_PYR-1 GQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1 ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK CVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA
Mvan_0269|M.vanbaalenii_PYR-1 CVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDP
Mvan_0269|M.vanbaalenii_PYR-1 LSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDP
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVE
Mvan_0269|M.vanbaalenii_PYR-1 ILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVE
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTT
Mvan_0269|M.vanbaalenii_PYR-1 FAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRRTA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDS
Mvan_0269|M.vanbaalenii_PYR-1 ADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK REP--VAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRL
Mvan_0269|M.vanbaalenii_PYR-1 QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDAT
Mvan_0269|M.vanbaalenii_PYR-1 AAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEAT
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAA
Mvan_0269|M.vanbaalenii_PYR-1 RPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGG
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LDAAES---DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGA
Mvan_0269|M.vanbaalenii_PYR-1 LDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLN
Mvan_0269|M.vanbaalenii_PYR-1 QHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLN
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVT
Mvan_0269|M.vanbaalenii_PYR-1 RITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYLVT
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVR
Mvan_0269|M.vanbaalenii_PYR-1 GGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIR
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVD
Mvan_0269|M.vanbaalenii_PYR-1 VVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVD
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANAFL
Mvan_0269|M.vanbaalenii_PYR-1 RVFAGKVWGAWHLSEAAADLQLDFFLGTSSIASVWGGYGQTAYGAANAFL
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
Mvan_0269|M.vanbaalenii_PYR-1 DGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRTLSPADALA
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
Mvan_0269|M.vanbaalenii_PYR-1 GLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDT
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE
Mvan_0269|M.vanbaalenii_PYR-1 ----APAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATE
Mb1554c|M.bovis_AF2122/97 --------------------------------------------------
Rv1527c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2340|M.marinum_M --------------------------------------------------
MUL_2010|M.ulcerans_Agy99 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MLBr_01229|M.leprae_Br4923 --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
Mvan_0269|M.vanbaalenii_PYR-1 IREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYL
Mb1554c|M.bovis_AF2122/97 --------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDSPDRL
Rv1527c|M.tuberculosis_H37Rv --------------MGKERTKTVDRTRVTPVAVIGMGCRLPGGIDSPDRL
MMAR_2340|M.marinum_M ---------------------------MTPVAVIGMACRLPGGIGSPEEL
MUL_2010|M.ulcerans_Agy99 -----------------------MQKSATPVAIIGMGCRLPGGVDSPEKL
MAV_2370|M.avium_104 ---------------------------MVPVAVIGMACRLPGAVDSPERL
TH_4621|M.thermoresistible__bu -------------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRL
MLBr_01229|M.leprae_Br4923 ----------------------MRAANVTPVAVIGMACRLPGGIDSPQRL
MSMEG_4727|M.smegmatis_MC2_155 ----------------------MTQNCVAPVAIIGMACRLPGAINSPQQL
MAB_3148c|M.abscessus_ATCC_199 -----------------------------------MGCRLPGGIESPEQF
Mflv_0405|M.gilvum_PYR-GCK LGDVLGLTEAATAPKAATVVSTAA---DEPIAIVAVSCRFPGAPN-PEAF
Mvan_0269|M.vanbaalenii_PYR-1 LGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPGAPD-PEAF
:.**:**. *: :
Mb1554c|M.bovis_AF2122/97 WEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNVGDFD
Rv1527c|M.tuberculosis_H37Rv WEALLRGDDLVTEIPADRWDIDEYYDPEPGVPGRTDCKWGAYLDNVGDFD
MMAR_2340|M.marinum_M WEALLRGDDLVTEIPADRWDADEYYDPEPGVPGRTVCKWGAFLDNVGDFD
MUL_2010|M.ulcerans_Agy99 WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MAV_2370|M.avium_104 WEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDVAGFD
TH_4621|M.thermoresistible__bu WEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFD
MLBr_01229|M.leprae_Br4923 WEALLRGDDLVTEIPKERWDADLYYDPEPGVPGRSVSRWGAFLDDVGGFD
MSMEG_4727|M.smegmatis_MC2_155 WEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDPAAFD
MAB_3148c|M.abscessus_ATCC_199 WQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDVGGFD
Mflv_0405|M.gilvum_PYR-GCK WDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFD
Mvan_0269|M.vanbaalenii_PYR-1 WEVLAGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFD
*: * * * : *:* *:* ::**:....*:: ::*.::: **
Mb1554c|M.bovis_AF2122/97 PEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMAS-RTGVFVGL
Rv1527c|M.tuberculosis_H37Rv PEFFGIGEKEAIAIDPQHRLLLETSWEAMEHGGLTPNQMAS-RTGVFVGL
MMAR_2340|M.marinum_M PEFFGITEKEAIAIDPQHRMLLETAWEAMEHGGLTPEQMAESLTGVFVGL
MUL_2010|M.ulcerans_Agy99 AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MAV_2370|M.avium_104 PEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVFIGL
TH_4621|M.thermoresistible__bu PEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGL
MLBr_01229|M.leprae_Br4923 CDFFGMTEREAIAIDPQHRLLLETSWDAIEHAGLDPATLAGSATGVFVGL
MSMEG_4727|M.smegmatis_MC2_155 PEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGVFMGL
MAB_3148c|M.abscessus_ATCC_199 ADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGV
Mflv_0405|M.gilvum_PYR-GCK PEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGV
Mvan_0269|M.vanbaalenii_PYR-1 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGV
:**.: :** ::**:* :*** *:.:*:.* : **:*:*:
Mb1554c|M.bovis_AF2122/97 VHTDYILVH-ADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTA
Rv1527c|M.tuberculosis_H37Rv VHTDYILVH-ADNQTFEGPYGNTGTNACFASGRVAYAMGLQGPAITVDTA
MMAR_2340|M.marinum_M NHGDYQFVH-VDANTFDGPYGNTGTNSCFASGRISYAMRLHGPAVTVDTA
MUL_2010|M.ulcerans_Agy99 SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MAV_2370|M.avium_104 THGDYQLLA-ADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALTVDTA
TH_4621|M.thermoresistible__bu SHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTA
MLBr_01229|M.leprae_Br4923 THGDYELLS-ADCGATEGPYGFTGTSNSFASGRVAYTLGLHGPAVTVDTA
MSMEG_4727|M.smegmatis_MC2_155 THNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTA
MAB_3148c|M.abscessus_ATCC_199 THNDYQLVA-ADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAG
Mflv_0405|M.gilvum_PYR-GCK AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mvan_0269|M.vanbaalenii_PYR-1 AANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
:* .: :* ***::. : :.**:::**:.
Mb1554c|M.bovis_AF2122/97 CSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATG
Rv1527c|M.tuberculosis_H37Rv CSSGLTAIHLACRSLHDGESDIALAGGVYVMLEPRRFASGSALGMLSATG
MMAR_2340|M.marinum_M CSSSLYATHLACNSLSEGESDLAFAAGVYVMLEPRRFASGSAQNMLSPTG
MUL_2010|M.ulcerans_Agy99 CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MAV_2370|M.avium_104 CSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLSPTG
TH_4621|M.thermoresistible__bu CSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTG
MLBr_01229|M.leprae_Br4923 CSSGLMAVHQARGSLDCGESDLALAGGVVVTLEPRKSVSGSLQGMLSPTG
MSMEG_4727|M.smegmatis_MC2_155 CSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTG
MAB_3148c|M.abscessus_ATCC_199 CAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTG
Mflv_0405|M.gilvum_PYR-GCK CSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVG
Mvan_0269|M.vanbaalenii_PYR-1 CSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVG
*::.* : * . :* *:.*:.:*.* : *.* . * ***..*
Mb1554c|M.bovis_AF2122/97 RCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAANQDGH
Rv1527c|M.tuberculosis_H37Rv RCHAFDVSADGFVSGEGCVMLALKRLPDALADGDRILAVIRGTAANQDGH
MMAR_2340|M.marinum_M HCHAFDVDADGFVSGEGSVVLLLKRLADAQRDGDRILAVMRGTAANQDGH
MUL_2010|M.ulcerans_Agy99 RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MAV_2370|M.avium_104 RCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAANQDGH
TH_4621|M.thermoresistible__bu RCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGR
MLBr_01229|M.leprae_Br4923 RCHAFDVAADGFVSGEGCVVLLLKRMPDAERDGDRILAVLRGTAANQDGH
MSMEG_4727|M.smegmatis_MC2_155 HCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGR
MAB_3148c|M.abscessus_ATCC_199 RCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGR
Mflv_0405|M.gilvum_PYR-GCK RCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGA
Mvan_0269|M.vanbaalenii_PYR-1 RCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGA
:*::* ***:* .**. :: ***: ** *.**: **: .:* ****
Mb1554c|M.bovis_AF2122/97 TVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPIEYAS
Rv1527c|M.tuberculosis_H37Rv TVNIATPSRSAQVAAYREALDVAGVDPATVGMVEAHGPGTPVGDPIEYAS
MMAR_2340|M.marinum_M TVNIATPSVEAQSAVYRAALATAGVDGASVGLVEAHGTGTPVGDPIEFES
MUL_2010|M.ulcerans_Agy99 SETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIEYRS
MAV_2370|M.avium_104 TVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPIEYAS
TH_4621|M.thermoresistible__bu TENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNS
MLBr_01229|M.leprae_Br4923 TVHIAAPSEQAQIAVYHKALAVGGVDPTTVGLIEAHGTGTPVGDPIEYAS
MSMEG_4727|M.smegmatis_MC2_155 TVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLEFSS
MAB_3148c|M.abscessus_ATCC_199 TVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTG
Mflv_0405|M.gilvum_PYR-GCK SSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQA
Mvan_0269|M.vanbaalenii_PYR-1 SSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQA
: *. ** .* .*: *. :*.**.***:***:* .
Mb1554c|M.bovis_AF2122/97 LAEVYGNDGP----CALASVKTNFGHTQSAAGALGLMKAVLALQHGVVPQ
Rv1527c|M.tuberculosis_H37Rv LAEVYGNDGP----CALASVKTNFGHTQSAAGALGLMKAVLALQHGVVPQ
MMAR_2340|M.marinum_M LARVYGIDRP----CALTSAKPNFGHMQAGAGVLGLMKAILALQHGVIPP
MUL_2010|M.ulcerans_Agy99 LAQVYGSGGSR---CMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MAV_2370|M.avium_104 LAEVYGIDGP----CALASVKTNFGHAQAASGALGMMKAILALQHGVVPR
TH_4621|M.thermoresistible__bu LTQVYGKTGP----CALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
MLBr_01229|M.leprae_Br4923 LAAVYGTAGR----CALASTKTNFGHMQSTSGPLGMMKAILALQHGVVPK
MSMEG_4727|M.smegmatis_MC2_155 LAEVYGTDGP----CALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
MAB_3148c|M.abscessus_ATCC_199 LAQVYGVDGP----CAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
Mflv_0405|M.gilvum_PYR-GCK AAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQ
Mvan_0269|M.vanbaalenii_PYR-1 AAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQ
: .*. : * *.*:** : :* *::* *:: * :*
Mb1554c|M.bovis_AF2122/97 NLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV
Rv1527c|M.tuberculosis_H37Rv NLHFTALPDKLAAIETNLFVPQEITPWPGADQETPRRAAVSSYGMTGTNV
MMAR_2340|M.marinum_M NIHFSRLPDEMAQIKSGLFVPQEITQWP-TNGEQTRTAAVSSYGISGTNV
MUL_2010|M.ulcerans_Agy99 MVHHTRLPDELAEIETGLYVPHEITPWP--EDQGPRRIAVSSFGMSGTNV
MAV_2370|M.avium_104 NLHFTQLPDDLARIDTKLFVPQQTTPWVS-NGGHPRRAAVSSYGLSGTNV
TH_4621|M.thermoresistible__bu NLHFTRLPDEMAAIETNLFVPQATTLWP-VREGCPRRAAVSSYGMSGTNV
MLBr_01229|M.leprae_Br4923 NLHFTRLPDQLAEITTELFVPQVNTPWP-VDVQQPRRAAVSSYGMSGTNV
MSMEG_4727|M.smegmatis_MC2_155 NLHFTRLPDQMAEIETGLFVPETITPWP-VREGQPRRAAVSAYGLSGTNV
MAB_3148c|M.abscessus_ATCC_199 NLHFTGIPDKLAPVKTNLFVPQTVIPWP-GKAQGPRRAGVSAYGMSGSNV
Mflv_0405|M.gilvum_PYR-GCK SLHFDTPSPHIPWDSLPVRVVDTAMPWQ--PNGRPRRAGVSSFGFTGTNA
Mvan_0269|M.vanbaalenii_PYR-1 SLHFENPSPHIPWDSLPVRVVDKAIPWQ--ADGRPRRAGVSSFGFTGTNA
:*. . .:. : * . * .* .**::*::*:*.
Mb1554c|M.bovis_AF2122/97 HAIVEQAPVPAPESGAPGD--------TPATPGIDGALLFALSASSQDAL
Rv1527c|M.tuberculosis_H37Rv HAIVEQAPVPAPESGAPGD--------TPATPGIDGALLFALSASSQDAL
MMAR_2340|M.marinum_M HAILEQAPETATHDAEP------------VSPAIEGALIFPLSATSADGL
MUL_2010|M.ulcerans_Agy99 HAILEEPPTPAPARDQAS-----------AEPGMASPLLFALSSTSADGL
MAV_2370|M.avium_104 HAILEQAPEPAPETVAP------------EGISAESPLLFPLSSTSADEL
TH_4621|M.thermoresistible__bu HAVLEQAPEPVQRPEES------------ADTDAAGPLVFALSSTSAEEL
MLBr_01229|M.leprae_Br4923 HAILEQAPEN-SGKDSP-----------AVS-KVNGPLLFPLSATSVEQL
MSMEG_4727|M.smegmatis_MC2_155 HAVLEQAPESPAETAAE-----------AISPKAGNALVFPVSASSADAL
MAB_3148c|M.abscessus_ATCC_199 HAVVEQAPPVESSTPPA------------VESPLGSQLIFPVSSTSAEEL
Mflv_0405|M.gilvum_PYR-GCK HVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEAL
Mvan_0269|M.vanbaalenii_PYR-1 HVLIEEAPLPQA--------ADPVEE---PDTRALPVGVLALSARSPEAL
*.::*:.* ::.:*: * : *
Mb1554c|M.bovis_AF2122/97 RQTAARLADWVDAQGP------ELAPADLAYTLARRRGHRPVRTAVLAAT
Rv1527c|M.tuberculosis_H37Rv RQTAARLADWVDAQGP------ELAPADLAYTLARRRGHRPVRTAVLAAT
MMAR_2340|M.marinum_M RQTAKRLADWVDAQGP------ELATSDLAYTLARRRGHRPVRTAVLADN
MUL_2010|M.ulcerans_Agy99 RQTARELAEWVGSRADS---ADSTEAVDLAYTLARRRAHRPVRTAVVAAS
MAV_2370|M.avium_104 RRTAGRLADWVHAHGD-------LALPDLAYTLARRRVHRPVRTAVLAGD
TH_4621|M.thermoresistible__bu RRTAGRLAEWVEAHTD------EVVPADLAYTLARRRAHRPVRTTVIADG
MLBr_01229|M.leprae_Br4923 RATAARMADWVDEHGSG---TKHTGLWDLGYTLSRRRGYRPVRTMVLASS
MSMEG_4727|M.smegmatis_MC2_155 RSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGD
MAB_3148c|M.abscessus_ATCC_199 RRTAARLADWVAERPE-------VAPGDVGYTLARRRAHRSVRTAVVADG
Mflv_0405|M.gilvum_PYR-GCK VALAQRYETWLTAHPE-------ADLADVCRTAGTGRSHFEHRAALVVDS
Mvan_0269|M.vanbaalenii_PYR-1 TALAQRYEAWLSAHPD-------ADLADVCRTAGTGRSHFEHRAALVVDS
* . *: *: * . * . *: ::.
Mb1554c|M.bovis_AF2122/97 TAELTEALREVATGETPYPPAVGQDDRGP--VWVFSGQGSQWAGMGADLL
Rv1527c|M.tuberculosis_H37Rv TAELTEALREVATGEPPYPPAVGQDDRGP--VWVFSGQGSQWAGMGADLL
MMAR_2340|M.marinum_M VSELSAGLHEIADDETPYQAAVGRDDRGP--VWVFSGQGSQWKAMGADLL
MUL_2010|M.ulcerans_Agy99 LPELVEGLQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMGADLL
MAV_2370|M.avium_104 RAQLIEALREVADGDTPYPAAVGRGDRGP--VWVFSGQGSQWAAMGADLL
TH_4621|M.thermoresistible__bu VEALTAGLREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAELL
MLBr_01229|M.leprae_Br4923 FAELSRGLREIAGSEIPYQSAVGQDDRGP--VWVFSGQGSQWAGMGAELF
MSMEG_4727|M.smegmatis_MC2_155 RGTLVEGLRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMGAELL
MAB_3148c|M.abscessus_ATCC_199 ADELIDALRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMGAELL
Mflv_0405|M.gilvum_PYR-GCK VESARIALTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELF
Mvan_0269|M.vanbaalenii_PYR-1 VAAAREGLAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARELF
.* :* . . . * .*:*:*****: .*. :*:
Mb1554c|M.bovis_AF2122/97 ATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTG---------IDRV
Rv1527c|M.tuberculosis_H37Rv ATEPVFAATIAAIEPLIAAESGFSVTEAMTAPEVVTG---------IDRV
MMAR_2340|M.marinum_M ANEPVFAATVAELEPLIAAESGFSVTEAMTAIETVTG---------IDRV
MUL_2010|M.ulcerans_Agy99 ANEPVFAATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDKV
MAV_2370|M.avium_104 ATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTG---------QDRV
TH_4621|M.thermoresistible__bu ATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTG---------IDRV
MLBr_01229|M.leprae_Br4923 AKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTG---------IDRV
MSMEG_4727|M.smegmatis_MC2_155 DREPAFAAAIAELEPLIAAESDFSVTEALTASETVTG---------IDRV
MAB_3148c|M.abscessus_ATCC_199 GKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTG---------IDRV
Mflv_0405|M.gilvum_PYR-GCK DTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFA
Mvan_0269|M.vanbaalenii_PYR-1 ETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTSFA
* .** :: : .: :.: . :* . .
Mb1554c|M.bovis_AF2122/97 QPTLFAMQVALAATMKS-YGVAPGAVIGHSLGESAAAVVAGALCLEDGVR
Rv1527c|M.tuberculosis_H37Rv QPTLFAMQVALAATMKS-YGVAPGAVIGHSLGESAAAVVAGALCLEDGVR
MMAR_2340|M.marinum_M QPTIFTMQVALAATMKS-YGVRPGAIIGHSLGESAAAVAAGALSLEDGAK
MUL_2010|M.ulcerans_Agy99 QPTLFAMQVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGAR
MAV_2370|M.avium_104 QPTLFTMQVALAATMKA-HGVRPGAVIGHSLGEAAAAVVAGALSLEDGAR
TH_4621|M.thermoresistible__bu QPTLFAIQVALAATMQS-YGVRPGAVIGHSLGEVAAAVVAGALSLEDGVK
MLBr_01229|M.leprae_Br4923 QPTIFAIQVALAATMKS-YGVYPGAVIGHSLGEAAAAVAAGALSCEDGLR
MSMEG_4727|M.smegmatis_MC2_155 QPTIFAVQVALAAAMRS-HGVVPGAVIGHSMGEVAASVVSGALSLEDGVK
MAB_3148c|M.abscessus_ATCC_199 QPTLFAMQVSLAATLAS-YGVRPGAVIGHSMGEVAAAVVSEALSLEDGVK
Mflv_0405|M.gilvum_PYR-GCK QPALFAVEMGLARLWQS-WGIVPDVVLGHSVGQYAAACVAGVFSLEDGAR
Mvan_0269|M.vanbaalenii_PYR-1 QPAIFAVEMGLARLWQS-WGIEPDVVLGHSVGQYAAACVAGVFSLEDGAR
**::*::::.** *: *..::***:*: **: .: :. *** :
Mb1554c|M.bovis_AF2122/97 VICRRSALMTRIAGAGAMASVELPAQQVLSELMARGVNDAVVAVVASPQS
Rv1527c|M.tuberculosis_H37Rv VICRRSALMTRIAGAGAMASVELPAQQVLSELMARGVNDAVVAVVASPQS
MMAR_2340|M.marinum_M VICRRSRLMTRISGSGAMASVELPAQQVLSELMARGINDVVVAVVASPQS
MUL_2010|M.ulcerans_Agy99 VISRRSKLMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQS
MAV_2370|M.avium_104 VICRRSRLMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVVASPQS
TH_4621|M.thermoresistible__bu VICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPES
MLBr_01229|M.leprae_Br4923 VICRRSQLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTS
MSMEG_4727|M.smegmatis_MC2_155 VICRRTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQS
MAB_3148c|M.abscessus_ATCC_199 VICRRSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQS
Mflv_0405|M.gilvum_PYR-GCK LMAERGRLFGSLPEGGRMVAVFADAK--RVEQVAADFPRVSVGAYNGP-N
Mvan_0269|M.vanbaalenii_PYR-1 LMAERGRMFGSLPEGGRMVAVFTDAK--LVEEIAGDFPRVSVGAYNGP-N
::..* : :. * . : .: .. . :.. .* .
Mb1554c|M.bovis_AF2122/97 TVIGGATQTVRDLVAAWEQRDVLAREVAVDVASHSPQVDPILDELAEALA
Rv1527c|M.tuberculosis_H37Rv TVIGGATQTVRDLVAAWEQRDVLAREVAVDVASHSPQVDPILDELAEALA
MMAR_2340|M.marinum_M TVIGGATDTVRELVAAWEQREVMAREVAVDVASHSPQVDPILDDLYDVLA
MUL_2010|M.ulcerans_Agy99 TVVGGATDTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATALA
MAV_2370|M.avium_104 TVIAGAAPTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALA
TH_4621|M.thermoresistible__bu TVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILA
MLBr_01229|M.leprae_Br4923 TVVGGDTQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLA
MSMEG_4727|M.smegmatis_MC2_155 TVVGGATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALA
MAB_3148c|M.abscessus_ATCC_199 TVVGGATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALE
Mflv_0405|M.gilvum_PYR-GCK TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAA
Mvan_0269|M.vanbaalenii_PYR-1 TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYAA
**:.* :..:: : : : .. * *: ::*:::::
Mb1554c|M.bovis_AF2122/97 EISPLQPEIPYYS-ATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQAALE
Rv1527c|M.tuberculosis_H37Rv EISPLQPEIPYYS-ATSFDPREEPYCDAYYWVDNLRHTVRFAAAVQAALE
MMAR_2340|M.marinum_M DLEPLTPEVPYYS-ATLFDPREEPYCDGSYWVDNLRHTVRFGAAVQAALE
MUL_2010|M.ulcerans_Agy99 DIVPSDPKVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALE
MAV_2370|M.avium_104 EISPRPPEVPYYS-ATLFDPREQPVCDARYWANNMRRMVRFATAVQAALE
TH_4621|M.thermoresistible__bu DLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALE
MLBr_01229|M.leprae_Br4923 DLKPTEPKVPYYS-ATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALK
MSMEG_4727|M.smegmatis_MC2_155 DLDPAEPEIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAALE
MAB_3148c|M.abscessus_ATCC_199 DLTPRTPVVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALD
Mflv_0405|M.gilvum_PYR-GCK QLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAA
Mvan_0269|M.vanbaalenii_PYR-1 QFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVAA
:: * :* . . . . ** : * *:*. :*::.
Mb1554c|M.bovis_AF2122/97 DGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHGLRALA
Rv1527c|M.tuberculosis_H37Rv DGYRVFTELTPHPLLTHAVDQTARSLDMSAAALAGMRREQPLPHGLRALA
MMAR_2340|M.marinum_M DGYRVFAELAPHPLLTRAVEKTAEGLDMPVAALAGMRREQPLPHGLRGLL
MUL_2010|M.ulcerans_Agy99 DGFRVFAELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGLL
MAV_2370|M.avium_104 DGYRVFAELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGLRGFV
TH_4621|M.thermoresistible__bu DGFRVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMV
MLBr_01229|M.leprae_Br4923 DGFRVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFI
MSMEG_4727|M.smegmatis_MC2_155 DGHRVFAELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFV
MAB_3148c|M.abscessus_ATCC_199 DGYRVFGELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFV
Mflv_0405|M.gilvum_PYR-GCK LGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADAL
Mvan_0269|M.vanbaalenii_PYR-1 LGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITEAL
* *: *: *:*:*. . : . .: .:*: :
Mb1554c|M.bovis_AF2122/97 GDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANT
Rv1527c|M.tuberculosis_H37Rv GDLYAAGAAVDFAVLYPTGRLINAPLPTWNHRRLLLDDT--TRRIAHANT
MMAR_2340|M.marinum_M ADLHSAGAAVDFSVLYPAGELVDAPLPAWTHQSLLLNRAGQDHQAQGGSS
MUL_2010|M.ulcerans_Agy99 TDVHSAGAAVDFSVLYPAGRLVNAPPPAWTHRRFFVDGEGQDSKAQGACS
MAV_2370|M.avium_104 ADLHNAGAAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCT
TH_4621|M.thermoresistible__bu GDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCT
MLBr_01229|M.leprae_Br4923 ADVHSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAV
MSMEG_4727|M.smegmatis_MC2_155 ADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDR-ELESSAPGVPS
MAB_3148c|M.abscessus_ATCC_199 GDLYTAGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTHT
Mflv_0405|M.gilvum_PYR-GCK AAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDGRVGA
Mvan_0269|M.vanbaalenii_PYR-1 AAAYVGGHRPDFGALYRRPGRAVALPTYPFQRRRFWPKTSGITTDG----
. .* **.. : . :
Mb1554c|M.bovis_AF2122/97 VAVHPLLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAY
Rv1527c|M.tuberculosis_H37Rv VAVHPLLGSHVRLPEEPERHVWQGEVGTVTQPWLADHQIHGAAALPGAAY
MMAR_2340|M.marinum_M VVVHPLLGSHVLLPEEPERHVWQSDVGTEALPWLADHQIHSAPALPGAAY
MUL_2010|M.ulcerans_Agy99 VTVHPLLGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAY
MAV_2370|M.avium_104 VAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAAY
TH_4621|M.thermoresistible__bu ITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAY
MLBr_01229|M.leprae_Br4923 QAVHPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAY
MSMEG_4727|M.smegmatis_MC2_155 VSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAY
MAB_3148c|M.abscessus_ATCC_199 VAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAY
Mflv_0405|M.gilvum_PYR-GCK SAGSGILGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVPGATY
Mvan_0269|M.vanbaalenii_PYR-1 PAVSGILGSAKDLASG--DTVYTSRWSVRSQPWLADHVIYGTVVVPGATY
:**. * . :: .. .*:.** : . . ***:*
Mb1554c|M.bovis_AF2122/97 CEMALAAARAVLG-EASEVRDIRFEQMLLLDDETPIGVTATVEAP--GVV
Rv1527c|M.tuberculosis_H37Rv CEMALAAARAVLG-EASEVRDIRFEQMLLLDDETPIGVTATVEAP--GVV
MMAR_2340|M.marinum_M CEMALVAARTILG-DAAEVRDVRFEQMLLLDDETPLSAVGSVKSP--GIV
MUL_2010|M.ulcerans_Agy99 CEMALAAAGEVFG-EAFEVRDLAFEQMLLLDEETPIDAVASLDSP--GAA
MAV_2370|M.avium_104 CEMALAAARSVLG-ATAEVRDIRFEQALLLDEQTTVDASASVSSP--GVL
TH_4621|M.thermoresistible__bu CEMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEP--GTL
MLBr_01229|M.leprae_Br4923 CEMALTAARVTLG-EASEVRDIKFEQTLLLDRETMASSAATVSAP--GVL
MSMEG_4727|M.smegmatis_MC2_155 CEMALAAVTPVLG-DTGEVHDLKFHDMLLLDDATPVWVSAAVTAP--GTA
MAB_3148c|M.abscessus_ATCC_199 CEMALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSA--DIL
Mflv_0405|M.gilvum_PYR-GCK AAMALAAVGTPAH-----AKDVFFYEPIILPEKSSREVQLTVHPSVDGES
Mvan_0269|M.vanbaalenii_PYR-1 AAMALAAVGTPAR-----VKDVFFYEPIILPEKASREVQLTLHPSEDGGQ
. *** *. .:.: * : : * : : . .
Mb1554c|M.bovis_AF2122/97 PLTVETSHDGRYTRQLAAVLHVVREADDAPDQPPQKNIAELLASHPHKVD
Rv1527c|M.tuberculosis_H37Rv PLTVETSHDGRYTRQLAAVLHVVREADDAPDQPPQKNIAELLASHPHKVD
MMAR_2340|M.marinum_M DFVVETFQDGGAVRRGGAVLHAVEDDD----QLPAYDIPALLAEHSRTED
MUL_2010|M.ulcerans_Agy99 NFVVQTHVDGETTRHATAALRASDDES----VPPAYDIAALLAAHPVSVN
MAV_2370|M.avium_104 HFTVQSHQGGEQARHASAVLGAATDEQ-----PAAHDLSALLTAHPHDDD
TH_4621|M.thermoresistible__bu EFAVETAKDGEHERRATAVLGAADDTE----PPQAHDIDALLAEHPTRIE
MLBr_01229|M.leprae_Br4923 EFAVETYEEGERVRRASAVLRALEDRV--NQQPASHSIDALIASHPLRTE
MSMEG_4727|M.smegmatis_MC2_155 EFGVETHQSGDRTQRATAVLRGDVD----AERPAAHSIDALLAAHPNRVD
MAB_3148c|M.abscessus_ATCC_199 EFVVETHDEGDVVKRATAVLGNGGDVD----MPIAYDLSALRAEHPHRES
Mflv_0405|M.gilvum_PYR-GCK KFQVHSRPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERLN
Mvan_0269|M.vanbaalenii_PYR-1 KFQVHSREYGERGTEWSLNAEGTVASGVDENPQAE--PSGPVDEAIERLN
: *.: * . .
Mb1554c|M.bovis_AF2122/97 ---GAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGD---TVLAEVNLPGP
Rv1527c|M.tuberculosis_H37Rv ---GAEVRQWLDKRGHRLGPAFAGLVDAYIAEGAGD---TVLAEVNLPGP
MMAR_2340|M.marinum_M ---GEELRARFDEHGVQYGPAFTGLGNAHIADGAVS---SVVAEVALPGA
MUL_2010|M.ulcerans_Agy99 ---GAELREAFVERGIQHGPAFSGLAIARTAETEGG---TVLAEVALPAS
MAV_2370|M.avium_104 ---GDEVRRRMDRRGVQYGPAFAGLGAVHSGD-ETG---TVLAEVALPRQ
TH_4621|M.thermoresistible__bu ---GDELRQWFDQRGVQFGPAFTGLTAARIPEGTVT---SVLAEVGLPGQ
MLBr_01229|M.leprae_Br4923 ---GADLRATFDAIGIQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGA
MSMEG_4727|M.smegmatis_MC2_155 ---GDELRAGFGTVGIGHGAAFAGLSEAYVATAAEP---TVVAAVALPGP
MAB_3148c|M.abscessus_ATCC_199 ---GDDLRASFDERGVQYGPAFQGLAAAYRGDETVR---SVLAEVTLPRD
Mflv_0405|M.gilvum_PYR-GCK RMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEA-----IGDILVGAE
Mvan_0269|M.vanbaalenii_PYR-1 RMRPQDLFETFADMELAWGPTWSGSLKSLWLGEGEA-----IGDILVGEE
:: : * :: * :. : :
Mb1554c|M.bovis_AF2122/97 LRSQVKAYGVHPVLLDACF-----QSVAAHPAVQGMADGGLLLPLGVRRL
Rv1527c|M.tuberculosis_H37Rv LRSQVKAYGVHPVLLDACF-----QSVAAHPAVQGMADGGLLLPLGVRRL
MMAR_2340|M.marinum_M MRSQQRAYAIHPALLDACF-----QAVGAHPDVQVAGNGGLMLPLGVRQI
MUL_2010|M.ulcerans_Agy99 IRFQQGAYGVHPALLDACF-----QSVAAG--VKSTGGGGLLLPLGVRSL
MAV_2370|M.avium_104 IRSQQAAYGAHPALLDACF-----QSVEAHPAVRALGDGALGLVLGIRRL
TH_4621|M.thermoresistible__bu IRSQQAPYGIHPALLDACF-----QSVAAHPDVQGAGSG-LLLPLGVRRL
MLBr_01229|M.leprae_Br4923 IRSQQASYTSHPALLDACF-----QSVIVAPEVQKAGAGGLLLPVYVRRL
MSMEG_4727|M.smegmatis_MC2_155 LRSGQRGYTVHPALLDACF-----QSVIAHPEVQNIASG-MLLPLGVRRL
MAB_3148c|M.abscessus_ATCC_199 VRAQQGSYIVHPALLDACF-----QSVIALPDVQEASKDALPLPKGVRSL
Mflv_0405|M.gilvum_PYR-GCK LAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSL
Mvan_0269|M.vanbaalenii_PYR-1 LAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVTL
: **.*:* * : : * :
Mb1554c|M.bovis_AF2122/97 RSYGSARHARYCCTTVTACG-VGVEADLDVLDEHGAVVLAVRGLQLGTGA
Rv1527c|M.tuberculosis_H37Rv RSYGSARHARYCCTTVTACG-VGVEADLDVLDEHGAVVLAVRGLQLGTGA
MMAR_2340|M.marinum_M RAYASTRNAHYCYARVTSVDTSAVEADLDVLDEHGTVLVAVRGLQLGTGV
MUL_2010|M.ulcerans_Agy99 RAYGPTRNAQYCYTRVTKADANGGEADLELLDEQGCVLLAVRGLRLGTGT
MAV_2370|M.avium_104 RAYGAARNAHYCYTRVTKADTSGVEADIDVLDEHGAVLLAVQGLRVGTSA
TH_4621|M.thermoresistible__bu QAFGPTRGARYCYARVTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAA
MLBr_01229|M.leprae_Br4923 LNYHSMRNAQYCLTRVKTSRAGECEVDLEVLDQSGAVLLLVEGLRLAGGA
MSMEG_4727|M.smegmatis_MC2_155 RAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGN
MAB_3148c|M.abscessus_ATCC_199 HAYESARATQYCYTRVTKVVGNEVEADIDLLDETGSVLIAVRGFRFGTGS
Mflv_0405|M.gilvum_PYR-GCK QEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAP
Mvan_0269|M.vanbaalenii_PYR-1 RDKMPRRFYCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTVKRAP
. * . *:: ** * : : . .
Mb1554c|M.bovis_AF2122/97 SQASER--ARVLGERLLSIEWHERELPENSHAEPG---AWLLISTCD-AT
Rv1527c|M.tuberculosis_H37Rv SQASER--ARVLGERLLSIEWHERELPENSHAEPG---AWLLISTCD-AT
MMAR_2340|M.marinum_M SEEGNR--DRVLNERLLTIEWQQRELPEVDAAEAG---AWLLISTSD-GA
MUL_2010|M.ulcerans_Agy99 SESGER--DRVLSERLLTLEWQQRQLPEVLDEETG---SWLLISASD-GE
MAV_2370|M.avium_104 SESGTR--DRVLTERLLNIEWRQRELPEPEHADAA---SWLLIGTTA-TA
TH_4621|M.thermoresistible__bu ADGDDR--DRVLGERLLTIEWQRRDLPEA-DSAAG---KWLLVSTSA-TA
MLBr_01229|M.leprae_Br4923 SEHECA--NRVLDERLFTVEWEPRELPEVTQRE---RGSWLVLGAS--AE
MSMEG_4727|M.smegmatis_MC2_155 SDKAEE--ERLLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAGDDDE
MAB_3148c|M.abscessus_ATCC_199 SDDEQR--DQLLNNRLLAIEWQQQRLPESVSGAPR---RWLLVSTGE-SV
Mflv_0405|M.gilvum_PYR-GCK REALLRGLGGDATRLLYTLGWHEVPVPESGDGAAPQG-TWLIGGFDELAV
Mvan_0269|M.vanbaalenii_PYR-1 REALLRGLGGDATRLLYTLGWHEVPAPASGD-AALNG-NWLIAGFDELAA
: . * : *. * **:
Mb1554c|M.bovis_AF2122/97 DLVAAQLTDALKVHDAQCTTMSWPQ-RADHAAQAARLRD--------QLG
Rv1527c|M.tuberculosis_H37Rv DLVAAQLTDALKVHDAQCTTMSWPQ-RADHAAQAARLRD--------QLG
MMAR_2340|M.marinum_M DMLAAELTDALKLHSAQCATTSWHENAADHAASAERLRN--------QLN
MUL_2010|M.ulcerans_Agy99 DLMATTLADALKSQGAECASMVWSA-QDDLAGGIEKLGA--------QLR
MAV_2370|M.avium_104 DVLASTLADTLKNHGAQCTTMAWPQ-QADHTAHAEQLRN--------QWR
TH_4621|M.thermoresistible__bu DVSATRLSDALKQAGAESTSMCWPQ-QADHADNVDRFRA--------GIA
MLBr_01229|M.leprae_Br4923 DPLVQQLGDALNADGGHCTAVSLPLGQIDTAQLCSLLSRDGVSSSIGHGA
MSMEG_4727|M.smegmatis_MC2_155 NPRAAGVVSALIGAGMPTTTMAWSHDADHDAQAAALTAR------LDEQP
MAB_3148c|M.abscessus_ATCC_199 DPWAAELIDSLKVRESEVSLIQWRP-NTDRVAALKLLYD--------QLE
Mflv_0405|M.gilvum_PYR-GCK SVPGCIPADR-TNPESLRQLLTDAH-----------------------GR
Mvan_0269|M.vanbaalenii_PYR-1 GVPGCIPFDRSTDPEPLGQLLAQAH-----------------------ER
. .
Mb1554c|M.bovis_AF2122/97 TGGFTGVFVLTAPQTGDPDA-ESPVRGGELVKHVVRIAREIPEITAQEPR
Rv1527c|M.tuberculosis_H37Rv TGGFTGVFVLTAPQTGDPDA-ESPVRGGELVKHVVRIAREIPEITAQEPR
MMAR_2340|M.marinum_M AGGFHNAVILLKPDSGDRDE-NSGVEGVECVRHVVRVVRELPEIMGEAPR
MUL_2010|M.ulcerans_Agy99 ARTNKGVVIVCGPRSGDADE-QSLLQGREQVRHLVRITRGLAELEGELPR
MAV_2370|M.avium_104 GDGFTGVVVLTGPKNGDNDQ-ESALLSRDHVQHLVRIARELTDLPGEPPR
TH_4621|M.thermoresistible__bu DG-VTGVVVLTGPKNGNPDD-AAARRGSDYVRHLVRITRELAEIDGDAPR
MLBr_01229|M.leprae_Br4923 LKGLTGVVVVTAPPATVAES-PALRRGRDYVSHLITIVREISELPGERPR
MSMEG_4727|M.smegmatis_MC2_155 LAGVAVIVGDSETGTDAHDVGADARRGADHVRHLVRIARTLADAVGEPPR
MAB_3148c|M.abscessus_ATCC_199 SGTFDGVLVVTAPGSEGGAD-RVVLQGADQVRHLVRITRELVDLPGEPPR
Mflv_0405|M.gilvum_PYR-GCK GLPFSGVVWRAARSDGDESDAEVAARLEAEIAELLGAVHTVQGGEVKLPG
Mvan_0269|M.vanbaalenii_PYR-1 GIGFSGVVWRAAAPSADESSTAMAARIETEIADLLSAVHTVQNGAVKLPG
. : .:: .: : . *
Mb1554c|M.bovis_AF2122/97 -LYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQ-
Rv1527c|M.tuberculosis_H37Rv -LYVLTHNAQAVLSGDRPNLEQGGMRGLLRVIGAEHPHLKASYVDVDEQ-
MMAR_2340|M.marinum_M -LFVVTRGAQTVLGGESANLEQAGLRGLLRVIGAEYPHLHTTHVDVDEH-
MUL_2010|M.ulcerans_Agy99 -LFVVTRQAQRVRPEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDES-
MAV_2370|M.avium_104 -LYVVTRNAQTVLPNDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDES-
TH_4621|M.thermoresistible__bu -LFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADD-
MLBr_01229|M.leprae_Br4923 -LFVVTRNAASIKTGDLANLEQVGLRGLIRVIDSEHPYLSVTQIDVEETN
MSMEG_4727|M.smegmatis_MC2_155 -LYVVTHRSQHVLDTDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDS-
MAB_3148c|M.abscessus_ATCC_199 -LFVVTRNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRH-
Mflv_0405|M.gilvum_PYR-GCK GLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGS-
Mvan_0269|M.vanbaalenii_PYR-1 GLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLVDVDGS-
*:::*. : : : .: *: *. * * * :*
Mb1554c|M.bovis_AF2122/97 --TGAESVARQLLAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDH
Rv1527c|M.tuberculosis_H37Rv --TGAESVARQLLAASGEDETAWRNDQWYTARLCPAPLRPEERQTTVVDH
MMAR_2340|M.marinum_M --SGSEVVARQLLSGSEEDETAWRCGQWYTARLSPMPLRPEERKTTVVEH
MUL_2010|M.ulcerans_Agy99 --TQAEQLAQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTVVDH
MAV_2370|M.avium_104 --TDAQALARQLLAGSEEDETAWRDGAWYTARLCPAPLLPEERHTAVANH
TH_4621|M.thermoresistible__bu --ADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDC
MLBr_01229|M.leprae_Br4923 QATIATQVARQLRSGSDEDETGWRDGEWYTARLRPGPLRQAERRTVVVQN
MSMEG_4727|M.smegmatis_MC2_155 --TAHEALVRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADN
MAB_3148c|M.abscessus_ATCC_199 --TAAQNVAGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRSTVATP
Mflv_0405|M.gilvum_PYR-GCK -PQAVQALAALLSTPVDEPELAVRQGKLLASRLLP-----WSRSGHLTVP
Mvan_0269|M.vanbaalenii_PYR-1 -PEAVLALAGLLAAPVDEPELAVRQGKLLASRLLP-----WARSGHLTVP
:. * * * . * . :** :.
Mb1554c|M.bovis_AF2122/97 AEAGMRLQIRTPGDLQTLEFAALDRVPPGPGEIEVAVTASSINFADVLVT
Rv1527c|M.tuberculosis_H37Rv AEAGMRLQIRTPGDLQTLEFAAFDRVPPGPGEIEVAVTASSINFADVLVT
MMAR_2340|M.marinum_M DTEGMRLQIRTPGDLQTMEFVAFDRVAPGPGQIEVAVSTSSINFADVLVS
MUL_2010|M.ulcerans_Agy99 ERDNMRLQIRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIA
MAV_2370|M.avium_104 ECDGMRLQIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVA
TH_4621|M.thermoresistible__bu ERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIA
MLBr_01229|M.leprae_Br4923 EHDGMRLEIRTPGDLDSLEFVAFDRVPPGPGEIEVAVTASTVNFADVLVA
MSMEG_4727|M.smegmatis_MC2_155 ASEGMRLVVRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVA
MAB_3148c|M.abscessus_ATCC_199 NNEGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVLNV
Mflv_0405|M.gilvum_PYR-GCK RGGDYVLAPTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNV
Mvan_0269|M.vanbaalenii_PYR-1 RSADYVLAPTERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFRDVLNV
. : * ::.: :. : .*. * ::* * : :** ***
Mb1554c|M.bovis_AF2122/97 FGRYQTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATF
Rv1527c|M.tuberculosis_H37Rv FGRYQTLDGRQPQLGTDFAGVVSAVGPGVSELKVGDRVGGMSPNGCWATF
MMAR_2340|M.marinum_M FGRYNSPDGQMPQLGTDFAGVVTAVGPDVTDHQVGDRVGGMSPHGCWATF
MUL_2010|M.ulcerans_Agy99 FGRYPSLEGRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSY
MAV_2370|M.avium_104 FGRYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTF
TH_4621|M.thermoresistible__bu FGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTF
MLBr_01229|M.leprae_Br4923 FGRYPTFEGYCQLLGIDFAGVVSAVGLNVTDHKVGDRVGGVSRNGCWTTF
MSMEG_4727|M.smegmatis_MC2_155 FGRCPSFDGRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNF
MAB_3148c|M.abscessus_ATCC_199 YGRYSSFEGR-QELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSF
Mflv_0405|M.gilvum_PYR-GCK LGLYP---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-AFASR
Mvan_0269|M.vanbaalenii_PYR-1 LGLYP---GDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQG-AFASR
* * * :* *.*: :* .*: **::* * .: .
Mb1554c|M.bovis_AF2122/97 VTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHS
Rv1527c|M.tuberculosis_H37Rv VTCDARLATRLPEGLTDAQAAAVTTASATAWYGLQDLARIKAGDKVLIHS
MMAR_2340|M.marinum_M VTCDGALATPIPAGLTDAQAAAVTTAHATAWYGLHDLGRIRAGDKVLIHS
MUL_2010|M.ulcerans_Agy99 LTCDANLAVTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHS
MAV_2370|M.avium_104 LTCDARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHS
TH_4621|M.thermoresistible__bu VTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHS
MLBr_01229|M.leprae_Br4923 VICDARHAVTLSPEVPLEEAAAVPTVAATAWYGLHDLARISQTDKVLIHS
MSMEG_4727|M.smegmatis_MC2_155 VTCEADLATKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHS
MAB_3148c|M.abscessus_ATCC_199 VVVDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHS
Mflv_0405|M.gilvum_PYR-GCK FNVPGQFLAPIPDGVSAVEAATIPAAALTVRL-SFDWAQVKSGDKVLIHA
Mvan_0269|M.vanbaalenii_PYR-1 FNVPAQLLAPIPDGIGAVDAATIPAAALTARL-AFDWAQLKPGDRVLIHA
. . . :. : .**: . *. : . : :::***:
Mb1554c|M.bovis_AF2122/97 ATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFA
Rv1527c|M.tuberculosis_H37Rv ATGGVGQAAIAIARAAGAQIYATAGNEKRRDLLRDMGIEHVYDSRSVEFA
MMAR_2340|M.marinum_M GTGGVGQAAIAIARAAGAEIYATAGSPKRRQVLRDMGIEHVYDSRSIEFA
MUL_2010|M.ulcerans_Agy99 ATGGVGQAAIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFA
MAV_2370|M.avium_104 ATGGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFA
TH_4621|M.thermoresistible__bu ATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFA
MLBr_01229|M.leprae_Br4923 GTGGVGQAAIAIARAAGCEIFATAGSPQRRQLLRDKGIEHVYDSRSLEFA
MSMEG_4727|M.smegmatis_MC2_155 ATGGVGQAAIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTAFA
MAB_3148c|M.abscessus_ATCC_199 GTGGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTDFA
Mflv_0405|M.gilvum_PYR-GCK ASGGVGLAAVQMAQQCGAEVYATASTFKR-ATLRKLGVKHVYDSRTTDFA
Mvan_0269|M.vanbaalenii_PYR-1 ASGGVGLAAIQMAQQHGAVVFATASTYKR-ATLRKLGVDHVYDSRTTEFA
.:**** **: :*: *. ::***.. * :.. *:.******: **
Mb1554c|M.bovis_AF2122/97 EQIRRDTAGYGVDIVLNSVTGAAQLAG-LKLLALGGRFIEIGKRDIYSNT
Rv1527c|M.tuberculosis_H37Rv EQIRRDTAGYGVDIVLNSVTGAAQLAG-LKLLALGGRFIEIGKRDIYSNT
MMAR_2340|M.marinum_M EAIRADTDGYGVDIVLNSLTGAAQRAG-LELLAWGGRFVEIGKRDIYGDT
MUL_2010|M.ulcerans_Agy99 DQIRRDTNGYGVDIVLNSLTGAAQRAG-LELLAFGGRFVEIGKADVYGNT
MAV_2370|M.avium_104 DLIRHDTDGYGVDIVLNSVTGAAQRAG-IELLAFGGRFVEIGKRDIYGDT
TH_4621|M.thermoresistible__bu DEIRRDTDGYGVDVVLNSLPGAAQRAG-LELLSFGGRFIEIGKRDIYGDT
MLBr_01229|M.leprae_Br4923 EQIHRDTKGYGVDVVLNSLPGAAQRAG-IELLAFGGRFVEIGKRDIYGDT
MSMEG_4727|M.smegmatis_MC2_155 DQIRTDTDGYGVDIVLNSVTGPAQRAG-LELLAFGGRFVEIGKRDIYADT
MAB_3148c|M.abscessus_ATCC_199 ELIRRDTDGYGVDIVLNSLTGAAQRAG-VELLTFGGRFIEIGKRDIYGDT
Mflv_0405|M.gilvum_PYR-GCK EQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVE
Mvan_0269|M.vanbaalenii_PYR-1 DQILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPE
: * ** * ***:****:.. . . :. : *** **.* *::
Mb1554c|M.bovis_AF2122/97 RLELLPFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEG------V
Rv1527c|M.tuberculosis_H37Rv RLELLPFRRNLAFYGLDLGLMSVSHPAAVRELLSTVYRLTVEG------V
MMAR_2340|M.marinum_M KMGLFPFRRNLSFYGVDLGMLSITHPRLIRELLTTVYQHTAEG------V
MUL_2010|M.ulcerans_Agy99 RMGLYPFRRGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG------V
MAV_2370|M.avium_104 RLGLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADG------A
TH_4621|M.thermoresistible__bu RLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG------V
MLBr_01229|M.leprae_Br4923 RLGLFPFRRNLSLYAVDLALLTYTHPDTVRRLLTTVYQRTAEG------V
MSMEG_4727|M.smegmatis_MC2_155 RLGLFPFRRNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADG------T
MAB_3148c|M.abscessus_ATCC_199 RLGLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEG------V
Mflv_0405|M.gilvum_PYR-GCK QMAAA--RPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG------A
Mvan_0269|M.vanbaalenii_PYR-1 QMAAA--RPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAE
:: * .:: : * : .* : * : ..
Mb1554c|M.bovis_AF2122/97 LPMPQSTHYPLAEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQAR
Rv1527c|M.tuberculosis_H37Rv LPMPQSTHYPLAEAATAIRVMGAAEHTGKLILDVPHAGRSSVVLPPEQAR
MMAR_2340|M.marinum_M LPMPQDTHYPLAEAATAIRVMGAADHTGKLLLDIPRSGRSAVVLPPEQVP
MUL_2010|M.ulcerans_Agy99 LSAPECTHYPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVE
MAV_2370|M.avium_104 LPMPESTHYPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVR
TH_4621|M.thermoresistible__bu LPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQAS
MLBr_01229|M.leprae_Br4923 LPVPQTTHYPIHNTANAVRLVAGAGHTGKVLLDVPHTGSSVAVVPPEQVR
MSMEG_4727|M.smegmatis_MC2_155 LPLPEITHYPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVP
MAB_3148c|M.abscessus_ATCC_199 LPLPEISPSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAP
Mflv_0405|M.gilvum_PYR-GCK WTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP----------
Mvan_0269|M.vanbaalenii_PYR-1 WVPLPAEIYPLTEARAAFRRMQQARHVGKIVLQMPKPLQP----------
*: :: :.* : * * **:::::* .
Mb1554c|M.bovis_AF2122/97 VFRSDGSYIITGGLGGLGLFLAEKMAN----AGAGRIVLSSRSQPSQKAL
Rv1527c|M.tuberculosis_H37Rv VFRSDGSYIITGGLGGLGLFLAEKMAN----AGAGRIVLSSRSQPSQKAL
MMAR_2340|M.marinum_M VLRADGSYIITGGLGGLGLFLAEKMAT----AGAGRIVLSSRSAPSQKAL
MUL_2010|M.ulcerans_Agy99 VFRGDGSYIITGGLGGLGLFFASKMAA----AGCGRIVLTARSQPNPKSR
MAV_2370|M.avium_104 AFRSDGAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKAL
TH_4621|M.thermoresistible__bu PFRSDGAYIVTGGMGGLGLYLAGEMAA----AGAGCIVLNGRSAPSGEAL
MLBr_01229|M.leprae_Br4923 TFRADGAYIVTGGLTGLGLFLGTEMAA----AGCGRIVLNSRSAPNPQAQ
MSMEG_4727|M.smegmatis_MC2_155 VFRGDGAYVITGGLGGLGLFLAERMAA----AGCGRIVVNSRSAPSTRSS
MAB_3148c|M.abscessus_ATCC_199 AFRRDGAYVVTGGLGGLGLFLARKLAA----AGVGRIILNGRSAPKPEAL
Mflv_0405|M.gilvum_PYR-GCK --QPDRSYLITGGLGAIGLHTAGYLAQ----LGAGDIVLTSRRAPDAAAQ
Mvan_0269|M.vanbaalenii_PYR-1 --RADRSYLITGGLGAIGLHTAAYLAQ----LGAGDLVLTSRRAPDADAR
: * :*::***: .:**. . :* * * ::: .* *. :
Mb1554c|M.bovis_AF2122/97 ETIELVRA-IGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAV
Rv1527c|M.tuberculosis_H37Rv ETIELVRA-IGSDVVVECGDIAQPDTADRLVTAATATGLPLRGVLHAAAV
MMAR_2340|M.marinum_M ETIELIRS-IGSDVVVECGDIAQPATAARLVANATATNLPLRGVLHAAAV
MUL_2010|M.ulcerans_Agy99 QAIERLRA-NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAV
MAV_2370|M.avium_104 ATLERIRQ-MGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAV
TH_4621|M.thermoresistible__bu RTIEQLRA-AGTEVIVECG----XXXRGQPVEVAVPT------ELRHADE
MLBr_01229|M.leprae_Br4923 ETIERLRA-GGADIQVECGDIAEPRVADRLVVAATQSGLPVRGVLHAAGV
MSMEG_4727|M.smegmatis_MC2_155 EIIELIRA-TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAV
MAB_3148c|M.abscessus_ATCC_199 AAIEQIRQ-GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAAL
Mflv_0405|M.gilvum_PYR-GCK QAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGV
Mvan_0269|M.vanbaalenii_PYR-1 RAIEEITERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGV
: : : . . : : *
Mb1554c|M.bovis_AF2122/97 VEDATLANITDELIER-DWAPKAYGAWQLHRAT-----ADQPLDWFCSFS
Rv1527c|M.tuberculosis_H37Rv VEDATLANITDELIER-DWAPKAYGAWQLHRAT-----ADQPLDWFCSFS
MMAR_2340|M.marinum_M VEDATLANITDELLDR-DWAPKVYGAWHLHQAT-----TDQPLDWFCSFS
MUL_2010|M.ulcerans_Agy99 VEDATLSNITDELIDR-DWSPKVYGSWNLHRAS-----TGQPLDWFCLFS
MAV_2370|M.avium_104 IEDATLANITDELIER-DWAAKVYGAWNLHCALQES-GAEQSLDWFCSFS
TH_4621|M.thermoresistible__bu HPDRRGAQLCDEFARG-EQGAQRNQHR-----------TDAGEGQRDAHP
MLBr_01229|M.leprae_Br4923 VEDATLTNVTDDLIDR-CWAPKVYGAWNLHQALQEG-KTAQLLDWFCSFS
MSMEG_4727|M.smegmatis_MC2_155 VEDATLANITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFS
MAB_3148c|M.abscessus_ATCC_199 VHDATLANITDELIDRGDWRPKVHGAWNLHEAT-----ADQPLDWFCSFS
Mflv_0405|M.gilvum_PYR-GCK LDDALLSQQSVERFRT-ALAPKAFGAVHLDRLT-----RVDDLDFFLVSS
Mvan_0269|M.vanbaalenii_PYR-1 LDDALLSQQSLERFRT-TLAPKAFGACHLDRLT-----AGDDLDFFIMSS
* :: : .: . .
Mb1554c|M.bovis_AF2122/97 SAAALVGSPGQGAYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRA-
Rv1527c|M.tuberculosis_H37Rv SAAALVGSPGQGAYAAANSWLDTFTHWRRAQDLPATSIAWGAWGQIGRA-
MMAR_2340|M.marinum_M SAAAMLGSPGQGAYAAANSWLDAFTHWRHNQNQPATAIAWGPWAEIGRA-
MUL_2010|M.ulcerans_Agy99 SGAALMGSPGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVGRA-
MAV_2370|M.avium_104 SAAALVGSPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIGRG-
TH_4621|M.thermoresistible__bu PGAVGHDQPDPGALSDTG---------LDERG--------GQFPGVGVQ-
MLBr_01229|M.leprae_Br4923 TAAALVGSPGQGAYAAANSWLDGFSYWRRAQGLASTTIAWGAWGELGLA-
MSMEG_4727|M.smegmatis_MC2_155 SAAALVGSPGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRG-
MAB_3148c|M.abscessus_ATCC_199 SIAALVGSPGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIGQG-
Mflv_0405|M.gilvum_PYR-GCK SVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMAS
Mvan_0269|M.vanbaalenii_PYR-1 SVSSLFGSPGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQGGMAS
. : ..*. . : :. :. * : *
Mb1554c|M.bovis_AF2122/97 --IAFAEQTGDAIAPEEGAYAFETLLRHNRAYSGYAPVIGSPWLTAFAQH
Rv1527c|M.tuberculosis_H37Rv --IAFAEQTGDAIAPEEGAYAFETLLRHNRAYSGYAPVIGSPWLTAFAQH
MMAR_2340|M.marinum_M --IALAESSDAAIAPDEGAYAFQTLLRHNRTYTGYAPIIGAPWVTAFAER
MUL_2010|M.ulcerans_Agy99 --TFLAEGGEIMIAPDEGMYAFEQMLRHARTYTGYIPIIGAPWLADLVRR
MAV_2370|M.avium_104 --AALADSADVAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQR
TH_4621|M.thermoresistible__bu --IPVADPG--VGIDHRGAVRVDSGVPAQQGVDGEVVRHRTLSSVRSGRS
MLBr_01229|M.leprae_Br4923 --TALAEMAGVAIAPTEGARVFQTLLRYNRPYSCYAPIMETPWLKSFAQH
MSMEG_4727|M.smegmatis_MC2_155 --TAMAEGD-NAIAPDEGAYAFEAILRHDRVYNGYAPVLGASWLTAFAQR
MAB_3148c|M.abscessus_ATCC_199 --THLAQNAEAAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVER
Mflv_0405|M.gilvum_PYR-GCK SEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVL
Mvan_0269|M.vanbaalenii_PYR-1 SEAATANIGAQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVL
*: . .
Mb1554c|M.bovis_AF2122/97 SP-----FAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVG
Rv1527c|M.tuberculosis_H37Rv SP-----FAEKFQSLGQNRSGTSKFLAELVDLPREEWPDRLRRLLSKQVG
MMAR_2340|M.marinum_M SK-----FAEAFKALEQGRSGSSKFRSELDALPLDEWPGQLRRMVAEQVS
MUL_2010|M.ulcerans_Agy99 SP-----WAEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQAS
MAV_2370|M.avium_104 SP-----FAEAFRANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVS
TH_4621|M.thermoresistible__bu SR-----WTAPGSRCGSGRRYGG---------------ESCRRTTGPAAG
MLBr_01229|M.leprae_Br4923 SR-----FAEAFRSISQGQKDKSKFLAELKVLPRDEWPSMIRRLVSEQIS
MSMEG_4727|M.smegmatis_MC2_155 SP-----FAELFLADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVG
MAB_3148c|M.abscessus_ATCC_199 SP-----FAQAFRDAGQNQTETNKFLDELRALPREEWPTRLRKLVAEQVG
Mflv_0405|M.gilvum_PYR-GCK GSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQ
Mvan_0269|M.vanbaalenii_PYR-1 GSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREVQ
. .
Mb1554c|M.bovis_AF2122/97 --LILRRTIDTDRLLSEYGLDSLSSQELRARVEAETG--IRISATEIN--
Rv1527c|M.tuberculosis_H37Rv --LILRRTIDTDRLLSEYGLDSLSSQELRARVEAETG--IRISATEIN--
MMAR_2340|M.marinum_M --LILRRTIDPDRQLSEYGLDSLGNLELRTRVQSETG--IRISSTDI---
MUL_2010|M.ulcerans_Agy99 --VILRRTVDADRPFVEYGLDSLGMLEMRTHIETETG--VRLSPKVIASH
MAV_2370|M.avium_104 --LILRRNVDPDRPLPEYGLDSLGGLELLTRIQTETG--IRVSPADIAAI
TH_4621|M.thermoresistible__bu --AAARRGRTRRRRRPRRPPPPPDRVRHRAGPAHGPV--RR---------
MLBr_01229|M.leprae_Br4923 --LLLRRTIDPDRLLSDYGLDSLGNLELRTRIETETG--IRISPTKIT--
MSMEG_4727|M.smegmatis_MC2_155 --LLLRRTVDPDRPLSEYGLDSLGHLELRTRIETETG--VRVSAMDMT--
MAB_3148c|M.abscessus_ATCC_199 --LVLRRSIDPDRSLPDYGLDSLGNLEIRTRIQADTG--VRIGPADVS--
Mflv_0405|M.gilvum_PYR-GCK NFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDY
Mvan_0269|M.vanbaalenii_PYR-1 NFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDY
: . .
Mb1554c|M.bovis_AF2122/97 TTVRGLADLMCDKLAADRDAPAPA---------------------
Rv1527c|M.tuberculosis_H37Rv TTVRGLADLMCDKLAADRDAPAPA---------------------
MMAR_2340|M.marinum_M TTVRGLADHLFAQLAPEEAAASSQ---------------------
MUL_2010|M.ulcerans_Agy99 NTARALSQHLADTLAEEEAQPAAS---------------------
MAV_2370|M.avium_104 GTIRGLADLLRDKLTPAGAAQAERV--------------------
TH_4621|M.thermoresistible__bu ---------------------------------------------
MLBr_01229|M.leprae_Br4923 -TIRSLAEHLCEELAATEAESAVTAT-------------------
MSMEG_4727|M.smegmatis_MC2_155 -TIRGLAQRLCEMLDTDDAVSAPS---------------------
MAB_3148c|M.abscessus_ATCC_199 -TVRSLAAHIYDRLAEQESEVASS---------------------
Mflv_0405|M.gilvum_PYR-GCK PTIGGLAEYLVAQLPD-----AETPQAAPQSESEPGPDVTE----
Mvan_0269|M.vanbaalenii_PYR-1 PTIGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG