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M. leprae Br4923 MLBr_00139 (mas)

annotation: putative mycocerosic synthase
coordinates: 194248 - 200598
length: 2116

METSVTPIAVIGMGCRLPGGINSPDKLWESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFL
DDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGLTHEDYLVLTTAAG
GLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTACSSGLMAVHLACRSLHDGESDLALAGGCAVLLEP
HASVAASAQGMLSSTGRCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGGTETL
MMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPIEYRSLARVYGAGTPCALGSAKSNMGHST
ASAGTVGLIKAILSLRNGLVPPLLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGT
NVHVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQLATWVEEHQDSVVLSDLAY
TLARGRAHRPVRTAVVAADLPELVEGLCEIADGDALYDAVVGHGDRGPVWVFSGQGSQWASMGVQLLANE
PVFAATITKLEPVIAAESSFSVTEAITAPETVTGIDKVQPSVFAVQVALATTMEQTYGVRPGAVIGHSMG
ESAAAVVAGALSLEDAARVICRRSKLMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTV
IGGATETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALADIAPMTPKVPYYSATLFDPREL
PVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRVFAELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMP
YGLRGLLADLHSAGAALDFAALYPAGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPLLGSHVRL
LEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALAAAVEVFGEAAEVRAIAFEQMLLLAAET
PIDAIASVDAPGVINFVVQANQDGEKMRNATATLHAAEDDCPPPAYDIAALLEAHPNSVNGTDLRESFAE
RGVQLGAAFAGLATAHTAEAESGTVLAEVALPASIRFQQSSYQIHPALLDACFQSVGAGVDATKVGSRAG
LLLPLGVRSLRVYRPTRNARYCYTRLTKIEPRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDRQL
SERLLTIGWQQRTLPESVHVEPGSWLLIDTFNASAIPDMWASTLTDALKSYGTQGTECTNLSWLIQDDPV
VSRERLGRQLRGRDGVVILCGPRAGAPDEQSLLAAREQVRHLVRIIRELAELEGELPRLFVVTRQAQIVQ
SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERVAQQLLSGSEEDETAWRNGDWYVARLNPS
PLSHEDRRTVVLNPEHDGLRVHVRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPI
IDDRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLTCDANLAVTLPSGLTDEQAITAATA
HATAWYGLNDLAGIKVGDKVLIHSATGGVGQAAISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRS
VEFAEQIRRDTDGYGVDIVLNSLTGAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFRRGLTFYYLD
LALMSVTQPDRVRELLATVFNLTADGVLTAPECTHYPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVA
VPPEQAPVYRRDGSYIITGGLGGLGLFFASKLAEAGCGRIVLTARSQPNPKARQTIERLCAAGADIVVEC
GNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTNITDELIDRDWSPKVYGSWNLHCATIGQPLD
WFCLFSSGAALLGSPGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEIMITPDE
GAYAFEMLVRYDRPYSGYIPILGAPWLPDLVRRSPWAEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLR
RLLVEQASVILRRTIDADRSFIEYGLDSLGMLEMRTHIESETGIRLTPKVIATNNTARALAQYLADTLAE
EEGVAAPAAMVSPETP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00139mas-100% (2116)putative mycocerosic synthase
M. leprae Br4923MLBr_01229pks30.060.00% (2130) mycocerosic acid synthase (polyketide synthase)
M. leprae Br4923MLBr_02355-0.038.48% (2165) polyketide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2965cmas0.087.87% (2118) multifunctional mycocerosic acid synthase membrane-associated
M. gilvum PYR-GCKMflv_0405-0.033.71% (2186) beta-ketoacyl synthase
M. tuberculosis H37RvRv2940cmas0.087.91% (2118) multifunctional mycocerosic acid synthase membrane-associated
M. abscessus ATCC 19977MAB_3148c-0.058.87% (2098) polyketide synthase Pks5
M. marinum MMMAR_1767mas0.075.89% (2115) multifunctional mycocerosic acid synthase membrane-associated
M. avium 104MAV_2370-0.064.07% (2104) mycocerosic acid synthase
M. smegmatis MC2 155MSMEG_4727-0.059.94% (2127) mycocerosic acid synthase
M. thermoresistible (build 8)TH_4621-0.063.83% (1822) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2010mas0.075.79% (2115) multifunctional mycocerosic acid synthase membrane-associated
M. vanbaalenii PYR-1Mvan_0269-0.034.40% (2183) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
Mvan_0269|M.vanbaalenii_PYR-1       MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1       WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
Mvan_0269|M.vanbaalenii_PYR-1       RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mvan_0269|M.vanbaalenii_PYR-1       EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1       GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
Mvan_0269|M.vanbaalenii_PYR-1       CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
Mvan_0269|M.vanbaalenii_PYR-1       DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1       GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP-LAAEPAQ
Mvan_0269|M.vanbaalenii_PYR-1       VEVVKETIPWER---DGGPRIAGVSSFGFAGTNAHVILEEAPEQAAAPGP
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          ESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAGTA
Mvan_0269|M.vanbaalenii_PYR-1       VQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAGAG
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          RSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1       RAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWLFT
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          GQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVL
Mvan_0269|M.vanbaalenii_PYR-1       GQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE---
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          DTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1       ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          CVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPA
Mvan_0269|M.vanbaalenii_PYR-1       CVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEFPS
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          LSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDP
Mvan_0269|M.vanbaalenii_PYR-1       LSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALLDP
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          ILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVE
Mvan_0269|M.vanbaalenii_PYR-1       ILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQPVE
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          FAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRRTT
Mvan_0269|M.vanbaalenii_PYR-1       FAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRRTA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          ADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDS
Mvan_0269|M.vanbaalenii_PYR-1       ADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFRDN
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          REP--VAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRL
Mvan_0269|M.vanbaalenii_PYR-1       QDPDGSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTLDVLSRL
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          AAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDAT
Mvan_0269|M.vanbaalenii_PYR-1       AAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEAT
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          RPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAA
Mvan_0269|M.vanbaalenii_PYR-1       RPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGG
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          LDAAES---DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGA
Mvan_0269|M.vanbaalenii_PYR-1       LDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          QHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLN
Mvan_0269|M.vanbaalenii_PYR-1       QHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLN
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          RIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVT
Mvan_0269|M.vanbaalenii_PYR-1       RITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDATYLVT
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          GGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVR
Mvan_0269|M.vanbaalenii_PYR-1       GGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQHSCQIR
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          VVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVD
Mvan_0269|M.vanbaalenii_PYR-1       VVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSLEDSEVD
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          RVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANAFL
Mvan_0269|M.vanbaalenii_PYR-1       RVFAGKVWGAWHLSEAAADLQLDFFLGTSSIASVWGGYGQTAYGAANAFL
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
Mvan_0269|M.vanbaalenii_PYR-1       DGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRTLSPADALA
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          GLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
Mvan_0269|M.vanbaalenii_PYR-1       GLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAELEREVPDT
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAE
Mvan_0269|M.vanbaalenii_PYR-1       ----APAATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAEITRVDATE
                                                                                      

Mb2965c|M.bovis_AF2122/97           --------------------------------------------------
Rv2940c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00139|M.leprae_Br4923          --------------------------------------------------
MMAR_1767|M.marinum_M               --------------------------------------------------
MUL_2010|M.ulcerans_Agy99           --------------------------------------------------
MAV_2370|M.avium_104                --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK          IREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYL
Mvan_0269|M.vanbaalenii_PYR-1       IREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPRLSDVADYL
                                                                                      

Mb2965c|M.bovis_AF2122/97           -----------------------MESRVTPVAVIGMGCRLPGGINSPDKL
Rv2940c|M.tuberculosis_H37Rv        -----------------------MESRVTPVAVIGMGCRLPGGINSPDKL
MLBr_00139|M.leprae_Br4923          -----------------------METSVTPIAVIGMGCRLPGGINSPDKL
MMAR_1767|M.marinum_M               -----------------------MQKPATPVAIIGMGCRLPGGVDSPEKL
MUL_2010|M.ulcerans_Agy99           -----------------------MQKSATPVAIIGMGCRLPGGVDSPEKL
MAV_2370|M.avium_104                ---------------------------MVPVAVIGMACRLPGAVDSPERL
TH_4621|M.thermoresistible__bu      -------------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRL
MSMEG_4727|M.smegmatis_MC2_155      ----------------------MTQNCVAPVAIIGMACRLPGAINSPQQL
MAB_3148c|M.abscessus_ATCC_199      -----------------------------------MGCRLPGGIESPEQF
Mflv_0405|M.gilvum_PYR-GCK          LGDVLGLTEAATAPKAATVVSTAA---DEPIAIVAVSCRFPGAPN-PEAF
Mvan_0269|M.vanbaalenii_PYR-1       LGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVSCRFPGAPD-PEAF
                                                                       :.**:**. : *: :

Mb2965c|M.bovis_AF2122/97           WESLLRGDDLVTEIPPDRWDADDYYDPEPGVPGRSVSRWGGFLDDVAGFD
Rv2940c|M.tuberculosis_H37Rv        WESLLRGDDLVTEIPPDRWDADDYYDPEPGVPGRSVSRWGGFLDDVAGFD
MLBr_00139|M.leprae_Br4923          WESLLRGDNLVTEVPPDRWDVDDFYDPEPGVPGRSVSRWGGFLDDVAGFD
MMAR_1767|M.marinum_M               WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MUL_2010|M.ulcerans_Agy99           WESLLRGDDLVSEIPPDRWDVDDYYDPEPGVPGRTVSRWGGFIDDVAGFD
MAV_2370|M.avium_104                WEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDVAGFD
TH_4621|M.thermoresistible__bu      WEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSRWGAFLDDVAGFD
MSMEG_4727|M.smegmatis_MC2_155      WEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSKWGAFLDDPAAFD
MAB_3148c|M.abscessus_ATCC_199      WQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSKWGAFLEDVGGFD
Mflv_0405|M.gilvum_PYR-GCK          WDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFD
Mvan_0269|M.vanbaalenii_PYR-1       WEVLAGGVDAIREVPEDRFDIDEFYDPDPDAAGKTYTRFGGFLDGIDGFD
                                    *: *  * : : *:*  *:*  :::**:....*:: :::*.*::    **

Mb2965c|M.bovis_AF2122/97           AEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSSTAVFTGL
Rv2940c|M.tuberculosis_H37Rv        AEFFGISEREATSIDPQQRLLLETSWEAIEHAGLDPASLAGSSTAVFTGL
MLBr_00139|M.leprae_Br4923          AEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPASLAGSSTAVFTGL
MMAR_1767|M.marinum_M               AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MUL_2010|M.ulcerans_Agy99           AEFFGVSEREATSIDPQHRQLLETAWEAIEHAGLDPASLSGSSTGVFVGL
MAV_2370|M.avium_104                PEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVFIGL
TH_4621|M.thermoresistible__bu      PEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGL
MSMEG_4727|M.smegmatis_MC2_155      PEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNPAGLAGSATGVFMGL
MAB_3148c|M.abscessus_ATCC_199      ADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGV
Mflv_0405|M.gilvum_PYR-GCK          PEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGV
Mvan_0269|M.vanbaalenii_PYR-1       PEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAPADLRGSRTGIFVGV
                                    .:**.:. ***  ::**:* :*** *:.:*:.*     : .* *.:* *:

Mb2965c|M.bovis_AF2122/97           THEDYLVLT-TTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTA
Rv2940c|M.tuberculosis_H37Rv        THEDYLVLT-TTAGGLASPYVVTGLNNSVASGRIAHTLGLHGPAMTFDTA
MLBr_00139|M.leprae_Br4923          THEDYLVLT-TAAGGLASPYVVTGLNNSVASGRISHTLGLHGPAMTFDTA
MMAR_1767|M.marinum_M               SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MUL_2010|M.ulcerans_Agy99           SHEDYLVRS-VLAGDLAGPYASTGLINSVASGRIAHTLGLHGPAMTVDTA
MAV_2370|M.avium_104                THGDYQLLA-ADTRSVEGAYGFSGSNFSLASGRIAYALGVHGPALTVDTA
TH_4621|M.thermoresistible__bu      SHDDYALLT-SDAGALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTA
MSMEG_4727|M.smegmatis_MC2_155      THNDYAHLA-ADAKALEGPYGFTGTSFSLASGRIAYALGVHGPAITVDTA
MAB_3148c|M.abscessus_ATCC_199      THNDYQLVA-ADAADLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAG
Mflv_0405|M.gilvum_PYR-GCK          AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
Mvan_0269|M.vanbaalenii_PYR-1       AANEYAHLLSSESIEKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTA
                                    :  :*       :     .:  :*      ***::. **:.**:::.*:.

Mb2965c|M.bovis_AF2122/97           CSSGLMAVHLACRSLHDGEADLALAGGCAVLLEPHACVAASAQGMLSSTG
Rv2940c|M.tuberculosis_H37Rv        CSSGLMAVHLACRSLHDGEADLALAGGCAVLLEPHASVAASAQGMLSSTG
MLBr_00139|M.leprae_Br4923          CSSGLMAVHLACRSLHDGESDLALAGGCAVLLEPHASVAASAQGMLSSTG
MMAR_1767|M.marinum_M               CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MUL_2010|M.ulcerans_Agy99           CSSGLLTVHLACRSLHEGESDLALAGGCALLLEPNGSVSLSSQGMLSPTG
MAV_2370|M.avium_104                CSSGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLSPTG
TH_4621|M.thermoresistible__bu      CSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTG
MSMEG_4727|M.smegmatis_MC2_155      CSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPRKAAGGSAAGMLSPTG
MAB_3148c|M.abscessus_ATCC_199      CAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTG
Mflv_0405|M.gilvum_PYR-GCK          CSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVG
Mvan_0269|M.vanbaalenii_PYR-1       CSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTSVAASRARMLSPVG
                                    *::.* ::* . ::*  *:.*:.****  : *.*    . *   ***..*

Mb2965c|M.bovis_AF2122/97           RCHSFDADADGFVRSEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGR
Rv2940c|M.tuberculosis_H37Rv        RCHSFDADADGFVRSEGCAMVLLKRLPDALRDGNRIFAVVRGTATNQDGR
MLBr_00139|M.leprae_Br4923          RCKSFAADADGFVRSEGCAMVLLKRLPDALRDGNRIFAMILGTATNQDGG
MMAR_1767|M.marinum_M               RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MUL_2010|M.ulcerans_Agy99           RCHAFDVDADGFVRSEGCAVVVLKRLSDALADGDRILAVVRGTAANQDGR
MAV_2370|M.avium_104                RCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAANQDGH
TH_4621|M.thermoresistible__bu      RCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGR
MSMEG_4727|M.smegmatis_MC2_155      HCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDRILAVIRGTATNQDGR
MAB_3148c|M.abscessus_ATCC_199      RCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGR
Mflv_0405|M.gilvum_PYR-GCK          RCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGA
Mvan_0269|M.vanbaalenii_PYR-1       RCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRVCAVIPSSAVNQDGA
                                    :*::*   ***:* .**. :: **** **: *.:*: *:: .:* **** 

Mb2965c|M.bovis_AF2122/97           TETLTMPSEDAQVAVYRAALAAAGVQPETVGVVEAHGTGTPIGDPIEYRS
Rv2940c|M.tuberculosis_H37Rv        TETLTMPSEDAQVAVYRAALAAAGVQPETVGVVEAHGTGTPIGDPIEYRS
MLBr_00139|M.leprae_Br4923          TETLMMPSEDAQVAVYQAALAVAGVEPETIGVVEAHGTGTPIGDPIEYRS
MMAR_1767|M.marinum_M               SETLLMPSETAQVAVYREALAAAGVDPASVGAVEVHGTGTPVGDPIEYRS
MUL_2010|M.ulcerans_Agy99           SETLLMPSETAQVAVYREALAAAGVDAASVGAVEVHGTGTPVGDPIEYRS
MAV_2370|M.avium_104                TVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPIEYAS
TH_4621|M.thermoresistible__bu      TENISTPSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNS
MSMEG_4727|M.smegmatis_MC2_155      TVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEAHGTGTPVGDPLEFSS
MAB_3148c|M.abscessus_ATCC_199      TVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTG
Mflv_0405|M.gilvum_PYR-GCK          SSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQA
Mvan_0269|M.vanbaalenii_PYR-1       SSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAHGTGTPLGDPIEVQA
                                    :     *.  **      .*  **:    :. :*.**.***:***:*  .

Mb2965c|M.bovis_AF2122/97           LARVYGAG----TPCALGSAKSNMGHSTASAGTVGLIKAILSLRHGVVPP
Rv2940c|M.tuberculosis_H37Rv        LARVYGAG----TPCALGSAKSNMGHSTASAGTVGLIKAILSLRHGVVPP
MLBr_00139|M.leprae_Br4923          LARVYGAG----TPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVPP
MMAR_1767|M.marinum_M               LAQVYGSGG---SRCMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MUL_2010|M.ulcerans_Agy99           LAQVYGSGG---SRCMLGSVKTNIGHSESAAGTVGLIKATLSLGHGVVPP
MAV_2370|M.avium_104                LAEVYGID----GPCALASVKTNFGHAQAASGALGMMKAILALQHGVVPR
TH_4621|M.thermoresistible__bu      LTQVYGKT----GPCALTSVKTNFGHAESAAGALGMMKAILALQHGVVPQ
MSMEG_4727|M.smegmatis_MC2_155      LAEVYGTD----GPCALGSIKTNFGHTQSAAGALGVMKAVLALQHNVIPQ
MAB_3148c|M.abscessus_ATCC_199      LAQVYGVD----GPCAVGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPP
Mflv_0405|M.gilvum_PYR-GCK          AAAAYAGARDADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQ
Mvan_0269|M.vanbaalenii_PYR-1       AAAAYGASRDADRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHNLLPQ
                                     : .*.          : * *:*:**  :::*: *::*  *:: :  :* 

Mb2965c|M.bovis_AF2122/97           LLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGTNV
Rv2940c|M.tuberculosis_H37Rv        LLHFNRLPDELSDVETGLFVPQAVTPWPNGNDHTPKRVAVSSFGMSGTNV
MLBr_00139|M.leprae_Br4923          LLHFDRLSDDLTEIETGLFVPQEVTPWPVGGYNTPKRVAVSSFGMSGTNV
MMAR_1767|M.marinum_M               MVHHTRLPDELAEIETGLYVPHEITPWP--EDQGPRRIAVSSFGMSGTNV
MUL_2010|M.ulcerans_Agy99           MVHHTRLPDELAEIETGLYVPHEITPWP--EDQGPRRIAVSSFGMSGTNV
MAV_2370|M.avium_104                NLHFTQLPDDLARIDTKLFVPQQTTPWVS-NGGHPRRAAVSSYGLSGTNV
TH_4621|M.thermoresistible__bu      NLHFTRLPDEMAAIETNLFVPQATTLWPV-REGCPRRAAVSSYGMSGTNV
MSMEG_4727|M.smegmatis_MC2_155      NLHFTRLPDQMAEIETGLFVPETITPWPV-REGQPRRAAVSAYGLSGTNV
MAB_3148c|M.abscessus_ATCC_199      NLHFTGIPDKLAPVKTNLFVPQTVIPWPG-KAQGPRRAGVSAYGMSGSNV
Mflv_0405|M.gilvum_PYR-GCK          SLHFDTPSPHIPWDSLPVRVVDTAMPWQP--NGRPRRAGVSSFGFTGTNA
Mvan_0269|M.vanbaalenii_PYR-1       SLHFENPSPHIPWDSLPVRVVDKAIPWQA--DGRPRRAGVSSFGFTGTNA
                                     :*.   . .:.  .  : * .    *       *:* .**::*::*:*.

Mb2965c|M.bovis_AF2122/97           HAIVEEAPAEASAP---ESSP--GDAEVGPRLFMLSSTSSDALRQTARQL
Rv2940c|M.tuberculosis_H37Rv        HAIVEEAPAEASAP---ESSP--GDAEVGPRLFMLSSTSSDALRQTARQL
MLBr_00139|M.leprae_Br4923          HVIVEEAPSEACAPDVPETSPGTGDATVGRQLFMLSSTSIAALRETARQL
MMAR_1767|M.marinum_M               HAILEEPPTPAPARDQAPAEP----GMASPLLFALSSTSADGLRQTAREL
MUL_2010|M.ulcerans_Agy99           HAILEEPPTPAPARDQASAEP----GMASPLLFALSSTSADGLRQTAREL
MAV_2370|M.avium_104                HAILEQAP-EPAPETVAPEGI----SAESPLLFPLSSTSADELRRTAGRL
TH_4621|M.thermoresistible__bu      HAVLEQAP-EPVQRPEESADT----DAAGPLVFALSSTSAEELRRTAGRL
MSMEG_4727|M.smegmatis_MC2_155      HAVLEQAPESPAETAAEAISP----KAGNALVFPVSASSADALRSTAQHL
MAB_3148c|M.abscessus_ATCC_199      HAVVEQAP-PVESSTPPAVES----PLGSQLIFPVSSTSAEELRRTAARL
Mflv_0405|M.gilvum_PYR-GCK          HVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEAL
Mvan_0269|M.vanbaalenii_PYR-1       HVLIEEAPLPQA--------ADPVEE---PDTRALPVGVLALSARSPEAL
                                    *.::*:.*                           .         :.  *

Mb2965c|M.bovis_AF2122/97           ATWV---EEHQD---CVAASDLAYTLARGRAHRPVRTAVVAANLPELVEG
Rv2940c|M.tuberculosis_H37Rv        ATWV---EEHQD---CVAASDLAYTLARGRAHRPVRTAVVAANLPELVEG
MLBr_00139|M.leprae_Br4923          ATWV---EEHQD---SVVLSDLAYTLARGRAHRPVRTAVVAADLPELVEG
MMAR_1767|M.marinum_M               AEWVGSRADSAD---STEAVDLAYTLARRRAHRPVRTAVVAASLPELVEG
MUL_2010|M.ulcerans_Agy99           AEWVGSRADSAD---STEAVDLAYTLARRRAHRPVRTAVVAASLPELVEG
MAV_2370|M.avium_104                ADWVHAHGD------LALP-DLAYTLARRRVHRPVRTAVLAGDRAQLIEA
TH_4621|M.thermoresistible__bu      AEWVEAHTD------EVVPADLAYTLARRRAHRPVRTTVIADGVEALTAG
MSMEG_4727|M.smegmatis_MC2_155      ADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSAVLAGDRGTLVEG
MAB_3148c|M.abscessus_ATCC_199      ADWVAERPE-------VAPGDVGYTLARRRAHRSVRTAVVADGADELIDA
Mflv_0405|M.gilvum_PYR-GCK          VALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVDSVESARIA
Mvan_0269|M.vanbaalenii_PYR-1       TALAQRYEAWLSAHPDADLADVCRTAGTGRSHFEHRAALVVDSVAAAREG
                                    .                   *:  * .  * .   *::::. .      .

Mb2965c|M.bovis_AF2122/97           LREVADGDALYDAAVGHGDRGP--VWVFSGQGSQWAAMGTQLLASEPVFA
Rv2940c|M.tuberculosis_H37Rv        LREVADGDALYDAAVGHGDRGP--VWVFSGQGSQWAAMGTQLLASEPVFA
MLBr_00139|M.leprae_Br4923          LCEIADGDALYDAVVGHGDRGP--VWVFSGQGSQWASMGVQLLANEPVFA
MMAR_1767|M.marinum_M               LQEVAEGDLMYEAAVGRGDRGP--VWVFSGQGSQWAAMGADLLANEPVFA
MUL_2010|M.ulcerans_Agy99           LQEVAEGDLVYEAAVGRGDRGP--VWVFSGQGSQWAAMGADLLANEPVFA
MAV_2370|M.avium_104                LREVADGDTPYPAAVGRGDRGP--VWVFSGQGSQWAAMGADLLATEPVFA
TH_4621|M.thermoresistible__bu      LREVADGDAPYQPAVGMDDKAP--VWVFSGQGSQWAGMGAELLATEQVFA
MSMEG_4727|M.smegmatis_MC2_155      LRQIADGEAMPQQAVTNDDRGP--VWVFSGQGSQWASMGAELLDREPAFA
MAB_3148c|M.abscessus_ATCC_199      LRGVAEGDAPYPAAVAQDDRGP--VWLFSGQGSQWAGMGAELLGKEPVFA
Mflv_0405|M.gilvum_PYR-GCK          LTDLAQNRLRPGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFA
Mvan_0269|M.vanbaalenii_PYR-1       LAELAQNRLRPGVVRGEHTHHPTTAWLFTGQGSQFPGMARELFETEPVFA
                                    *  :*:.      .     . *  .*:*:*****:..*. :*:  * .**

Mb2965c|M.bovis_AF2122/97           ATIAKLEPVIAAESGFSVTEAITAQQTVTG---------IDKVQPAVFAV
Rv2940c|M.tuberculosis_H37Rv        ATIAKLEPVIAAESGFSVTEAITAQQTVTG---------IDKVQPAVFAV
MLBr_00139|M.leprae_Br4923          ATITKLEPVIAAESSFSVTEAITAPETVTG---------IDKVQPSVFAV
MMAR_1767|M.marinum_M               ATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDKVQPTLFAM
MUL_2010|M.ulcerans_Agy99           ATVAAVEPIIAHESGFSVTEAMTAPEKVTG---------IDKVQPTLFAM
MAV_2370|M.avium_104                ATVAQAEPLIARESGFSVAEAMSAPQTVTG---------QDRVQPTLFTM
TH_4621|M.thermoresistible__bu      AKIAEIEPLVARESGFSVTEAMTASETVTG---------IDRVQPTLFAI
MSMEG_4727|M.smegmatis_MC2_155      AAIAELEPLIAAESDFSVTEALTASETVTG---------IDRVQPTIFAV
MAB_3148c|M.abscessus_ATCC_199      ETIARLEPLIHAESGFSVTDAISAPETVTG---------IDRVQPTLFAM
Mflv_0405|M.gilvum_PYR-GCK          DTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFAQPALFAV
Mvan_0269|M.vanbaalenii_PYR-1       DAVTRCADAVKDILPRPLLEVLFAADRESG----EALRHTSFAQPAIFAV
                                      ::     :      .: :.: *    :*          . .**::*::

Mb2965c|M.bovis_AF2122/97           QVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSK
Rv2940c|M.tuberculosis_H37Rv        QVALAATMEQTYGVRPGAVVGHSMGESAAAVVAGALSLEDAARVICRRSK
MLBr_00139|M.leprae_Br4923          QVALATTMEQTYGVRPGAVIGHSMGESAAAVVAGALSLEDAARVICRRSK
MMAR_1767|M.marinum_M               QVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGARVISRRSK
MUL_2010|M.ulcerans_Agy99           QVALAATMEKTYGVRPGAVIGHSLGEAAAAVVAGSLSLEDGARVISRRSK
MAV_2370|M.avium_104                QVALAATMKA-HGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICRRSR
TH_4621|M.thermoresistible__bu      QVALAATMQS-YGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSR
MSMEG_4727|M.smegmatis_MC2_155      QVALAAAMRS-HGVVPGAVIGHSMGEVAASVVSGALSLEDGVKVICRRTR
MAB_3148c|M.abscessus_ATCC_199      QVSLAATLAS-YGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICRRSQ
Mflv_0405|M.gilvum_PYR-GCK          EMGLARLWQS-WGIVPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGR
Mvan_0269|M.vanbaalenii_PYR-1       EMGLARLWQS-WGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGR
                                    ::.**       *: *..*:***:*: **: *:  :****..:::..* :

Mb2965c|M.bovis_AF2122/97           LMTRIAGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTS
Rv2940c|M.tuberculosis_H37Rv        LMTRIAGAGAMGSVELPAKQVNSELMARGIDDVVVSVVASPQSTVIGGTS
MLBr_00139|M.leprae_Br4923          LMNRVAGSGAMGSVELPAKQVNSELMARGIDDVVISVVASPQSTVIGGAT
MMAR_1767|M.marinum_M               LMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQSTVVGGAT
MUL_2010|M.ulcerans_Agy99           LMLRISGAGAMASVELPAKQVNSELMARGIDDVAVAVVASPQSTVVGGAT
MAV_2370|M.avium_104                LMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVVASPQSTVIAGAA
TH_4621|M.thermoresistible__bu      LCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGAT
MSMEG_4727|M.smegmatis_MC2_155      LMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQSTVVGGAT
MAB_3148c|M.abscessus_ATCC_199      LMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVGGAT
Mflv_0405|M.gilvum_PYR-GCK          LFGSLPEGGRMVAVFADAKRVEQVAAD--FPRVSVGAYNGP-NTVLSGPG
Mvan_0269|M.vanbaalenii_PYR-1       MFGSLPEGGRMVAVFTDAKLVEEIAGD--FPRVSVGAYNGP-NTVLSGPG
                                    :   :.  *    :   *: * .      .  * :..  .* .**:.*. 

Mb2965c|M.bovis_AF2122/97           DTVRDLIARWEQRDVMAREVAVDVASHSPQVDPILDDLAAALADIAPMTP
Rv2940c|M.tuberculosis_H37Rv        DTVRDLIARWEQRDVMAREVAVDVASHSPQVDPILDDLAAALADIAPMTP
MLBr_00139|M.leprae_Br4923          ETVRDLIAQWEQRDVMAREVAVDVASHSSQVDPILDDLAAALADIAPMTP
MMAR_1767|M.marinum_M               DTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATALADIVPSDP
MUL_2010|M.ulcerans_Agy99           DTVRDLVARWEQREVMAREVAVDVASHSPQVDPILEDLATALADIVPSDP
MAV_2370|M.avium_104                PTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALAEISPRPP
TH_4621|M.thermoresistible__bu      DTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTP
MSMEG_4727|M.smegmatis_MC2_155      ASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALADLDPAEP
MAB_3148c|M.abscessus_ATCC_199      ETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTPRTP
Mflv_0405|M.gilvum_PYR-GCK          EDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAP
Mvan_0269|M.vanbaalenii_PYR-1       EDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLDEFESYAAQFQFATP
                                      :.:::  :    : .  : .. * **  :**:::::     ::    *

Mb2965c|M.bovis_AF2122/97           KVPYYS-ATLFDPREQPVCDGAYWVDNLRNTVQFAAAVQAAMEDGYRVFA
Rv2940c|M.tuberculosis_H37Rv        KVPYYS-ATLFDPREQPVCDGAYWVDNLRNTVQFAAAVQAAMEDGYRVFA
MLBr_00139|M.leprae_Br4923          KVPYYS-ATLFDPRELPVCNGAYWVDNLRNTVQFAAAVQAAMEDGYRVFA
MMAR_1767|M.marinum_M               KVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALEDGFRVFA
MUL_2010|M.ulcerans_Agy99           KVPYYS-ATLFDPRERPTCDAAYWVDNLRNTVQFAAAVQAALEDGFRVFA
MAV_2370|M.avium_104                EVPYYS-ATLFDPREQPVCDARYWANNMRRMVRFATAVQAALEDGYRVFA
TH_4621|M.thermoresistible__bu      TVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFG
MSMEG_4727|M.smegmatis_MC2_155      EIPYYS-ATLYDPRDYADYDAYYWADNLRHTVRFSAAVQAALEDGHRVFA
MAB_3148c|M.abscessus_ATCC_199      VVPLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALDDGYRVFG
Mflv_0405|M.gilvum_PYR-GCK          TLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM
Mvan_0269|M.vanbaalenii_PYR-1       TLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM
                                     :*  .  .       .  :. **  : *. *:*: :*::.   *  *: 

Mb2965c|M.bovis_AF2122/97           ELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLPHGLRGLLTELHRAG
Rv2940c|M.tuberculosis_H37Rv        ELSPHPLLTHAVEQTGRSLDMSVAALAGMRREQPLPHGLRGLLTELHRAG
MLBr_00139|M.leprae_Br4923          ELSPHPLLTHAVEQTARNLDMSVAALAGMRREQSMPYGLRGLLADLHSAG
MMAR_1767|M.marinum_M               ELSPHPLLTHAVDQNARSLDMSAAALAGMRREQPLPHGLRGLLTDVHSAG
MUL_2010|M.ulcerans_Agy99           ELSPHPLLTHAVDQNARSLDMSAAVLAGMRREQPLPHGLRGLLTDVHSAG
MAV_2370|M.avium_104                ELAPHPLLVRALEQTARSREIPMAALAGMRRGQALPHGLRGFVADLHNAG
TH_4621|M.thermoresistible__bu      ELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDLFAAG
MSMEG_4727|M.smegmatis_MC2_155      ELSPHPLLTHPVEQTARSLDMPLAVFAAMRRQQEMPHGLLGFVADLHSAG
MAB_3148c|M.abscessus_ATCC_199      ELAPHPLLVYPAEQTARSLDIPMVALAGMRREQELPHGLRDFVGDLYTAG
Mflv_0405|M.gilvum_PYR-GCK          EIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADRRQIADALAAAYIGG
Mvan_0269|M.vanbaalenii_PYR-1       EIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDRRQITEALAAAYVGG
                                    *:.*:*:*. .  *       .  .: .:*:       :   :   . .*

Mb2965c|M.bovis_AF2122/97           AALDYSALYP-AGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITVHPL
Rv2940c|M.tuberculosis_H37Rv        AALDYSALYP-AGRLVDAPLPAWTHARLFIDDDGQEQRAQGACTITVHPL
MLBr_00139|M.leprae_Br4923          AALDFAALYP-AGRLLDAPLPVWTHPRLFIDTDGQEQRAQGACTVTVHPL
MMAR_1767|M.marinum_M               AAVDFSVLYP-AGRLVNAPLPAWTHRRFFVDGEGQDSKAQGACSVTVHPL
MUL_2010|M.ulcerans_Agy99           AAVDFSVLYP-AGRLVNAPPPAWTHRRFFVDGEGQDSKAQGACSVTVHPL
MAV_2370|M.avium_104                AAVDFSVLYP-TGRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHPL
TH_4621|M.thermoresistible__bu      AAVDFAALYP-SGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITVHPL
MSMEG_4727|M.smegmatis_MC2_155      AAVDFSVLYP-TGRLLDAPLPAWTHSTLLLDR-ELESSAPGVPSVSVHPL
MAB_3148c|M.abscessus_ATCC_199      GAVDFSVLYP-TGQLVDVPLPSWTRRSYLLDLSAQAQQGHGTHTVAVHPL
Mflv_0405|M.gilvum_PYR-GCK          HKPDFAALHEQRGVRLELPTYPFQRRRFWPKSAGMAIDGR-VGASAGSGI
Mvan_0269|M.vanbaalenii_PYR-1       HRPDFGALYRRPGRAVALPTYPFQRRRFWPKTSGITTDG-----PAVSGI
                                       *:..*:   *  :  *   : :                    :   :

Mb2965c|M.bovis_AF2122/97           LGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALA
Rv2940c|M.tuberculosis_H37Rv        LGSHVRLTEEPERHVWQGDVGTSVLSWLSDHQVHNVAALPGAAYCEMALA
MLBr_00139|M.leprae_Br4923          LGSHVRLLEEPERHIWQGDVGTAALSWLADHQVHNVAALPGAAYCEMALA
MMAR_1767|M.marinum_M               LGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAYCEMALA
MUL_2010|M.ulcerans_Agy99           LGAHVRLSEQPERHVWQTDVGTDTLSWLSDHQVRNVAALPGAAYCEMALA
MAV_2370|M.avium_104                LGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMALA
TH_4621|M.thermoresistible__bu      LGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEMALA
MSMEG_4727|M.smegmatis_MC2_155      LGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALA
MAB_3148c|M.abscessus_ATCC_199      LGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEMALS
Mflv_0405|M.gilvum_PYR-GCK          LGSGKDLASG--DSVYTSRLSVKTQPWLSDHVIYGTVVVPGATYAAMALA
Mvan_0269|M.vanbaalenii_PYR-1       LGSAKDLASG--DTVYTSRWSVRSQPWLADHVIYGTVVVPGATYAAMALA
                                    **.   * .     ::    ..   .*::** :  ... ***:*. ***:

Mb2965c|M.bovis_AF2122/97           AAAEVFGEA-AEVRDITFEQMLLLDEQTPIDAVASIDAP--GVVNFTVET
Rv2940c|M.tuberculosis_H37Rv        AAAEVFGEA-AEVRDITFEQMLLLDEQTPIDAVASIDAP--GVVNFTVET
MLBr_00139|M.leprae_Br4923          AAVEVFGEA-AEVRAIAFEQMLLLAAETPIDAIASVDAP--GVINFVVQA
MMAR_1767|M.marinum_M               AAGEVFGEA-FEVRDLAFEQMLLLDEETPIDAVASLDSP--GAANFVVQT
MUL_2010|M.ulcerans_Agy99           AAGEVFGEA-FEVRDLAFEQMLLLDEETPIDAVASLDSP--GAANFVVQT
MAV_2370|M.avium_104                AARSVLGAT-AEVRDIRFEQALLLDEQTTVDASASVSSP--GVLHFTVQS
TH_4621|M.thermoresistible__bu      AAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEP--GTLEFAVET
MSMEG_4727|M.smegmatis_MC2_155      AVTPVLGDT-GEVHDLKFHDMLLLDDATPVWVSAAVTAP--GTAEFGVET
MAB_3148c|M.abscessus_ATCC_199      AAAAVFGEG-SAVQSISFEQLLTLGESTPISATATAKSA--DILEFVVET
Mflv_0405|M.gilvum_PYR-GCK          AVGTPAHAK-----DVFFYEPIILPEKSSREVQLTVHPSVDGESKFQVHS
Mvan_0269|M.vanbaalenii_PYR-1       AVGTPARVK-----DVFFYEPIILPEKASREVQLTLHPSEDGGQKFQVHS
                                    *.             : * : : *   :   .  :   .  .  .* *.:

Mb2965c|M.bovis_AF2122/97           NRDGET----TRHATAALRAAEDDCPPPGYDITALLQAHPHAVN---GTA
Rv2940c|M.tuberculosis_H37Rv        NRDGET----TRHATAALRAAEDDCPPPGYDITALLQAHPHAVN---GTA
MLBr_00139|M.leprae_Br4923          NQDGEK----MRNATATLHAAEDDCPPPAYDIAALLEAHPNSVN---GTD
MMAR_1767|M.marinum_M               HVDGET----TRHATAALRASDDESVPPAYDIAALLAAHPVSVN---GAE
MUL_2010|M.ulcerans_Agy99           HVDGET----TRHATAALRASDDESVPPAYDIAALLAAHPVSVN---GAE
MAV_2370|M.avium_104                HQGGEQ----ARHASAVLGAATD-EQPAAHDLSALLTAHPHDDD---GDE
TH_4621|M.thermoresistible__bu      AKDGEH----ERRATAVLGAADDTEPPQAHDIDALLAEHPTRIE---GDE
MSMEG_4727|M.smegmatis_MC2_155      HQSGDR----TQRATAVLRGDVDAERPAAHSIDALLAAHPNRVD---GDE
MAB_3148c|M.abscessus_ATCC_199      HDEGDV----VKRATAVLGNGGDVDMPIAYDLSALRAEHPHRES---GDD
Mflv_0405|M.gilvum_PYR-GCK          RPYGERGAEWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERLNRMRPQE
Mvan_0269|M.vanbaalenii_PYR-1       REYGERGTEWSLNAEGTVASGVDENPQAE--PSGPVDEAIERLNRMRPQD
                                       *:       .* ..:    .                    .      

Mb2965c|M.bovis_AF2122/97           MRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVALPASIRFQQGAYR
Rv2940c|M.tuberculosis_H37Rv        MRESFAERGVTLGAAFGGLTTAHTAEAGAATVLAEVALPASIRFQQGAYR
MLBr_00139|M.leprae_Br4923          LRESFAERGVQLGAAFAGLATAHTAEAESGTVLAEVALPASIRFQQSSYQ
MMAR_1767|M.marinum_M               LREAFVERGIQHGPAFSGLAIARTAETEGGTVLAEVALPASIRFQQGAYG
MUL_2010|M.ulcerans_Agy99           LREAFVERGIQHGPAFSGLAIARTAETEGGTVLAEVALPASIRFQQGAYG
MAV_2370|M.avium_104                VRRRMDRRGVQYGPAFAGLGAVHSGDETGT-VLAEVALPRQIRSQQAAYG
TH_4621|M.thermoresistible__bu      LRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYG
MSMEG_4727|M.smegmatis_MC2_155      LRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYT
MAB_3148c|M.abscessus_ATCC_199      LRASFDERGVQYGPAFQGLAAAYRGDETVRSVLAEVTLPRDVRAQQGSYI
Mflv_0405|M.gilvum_PYR-GCK          LFETFADLELAWGPTWSGSLKSLWLG--EGEAIGDILVGAELAEQLGTEP
Mvan_0269|M.vanbaalenii_PYR-1       LFETFADMELAWGPTWSGSLKSLWLG--EGEAIGDILVGEELAEQLGTEP
                                    :   :    :  *.:: *             .:. : :   :        

Mb2965c|M.bovis_AF2122/97           IHPALLDACFQSVGAGVQAGTATG----GLLLPLGVRSLRAYGPTRNARY
Rv2940c|M.tuberculosis_H37Rv        IHPALLDACFQSVGAGVQAGTATG----GLLLPLGVRSLRAYGPTRNARY
MLBr_00139|M.leprae_Br4923          IHPALLDACFQSVGAGVDATKVGSR--AGLLLPLGVRSLRVYRPTRNARY
MMAR_1767|M.marinum_M               VHPALLDACFQSVAAGVKSTGGGG-----LLLPLGVRSLRAYGPTRNAQY
MUL_2010|M.ulcerans_Agy99           VHPALLDACFQSVAAGVKSTGGGG-----LLLPLGVRSLRAYGPTRNAQY
MAV_2370|M.avium_104                AHPALLDACFQSVEAHPAVRALGD---GALGLVLGIRRLRAYGAARNAHY
TH_4621|M.thermoresistible__bu      IHPALLDACFQSVAAHPDVQGAGS---GLL-LPLGVRRLQAFGPTRGARY
MSMEG_4727|M.smegmatis_MC2_155      VHPALLDACFQSVIAHPEVQNIAS---GML-LPLGVRRLRAYGSTRNVRY
MAB_3148c|M.abscessus_ATCC_199      VHPALLDACFQSVIALPDVQEASK---DALPLPKGVRSLHAYESARATQY
Mflv_0405|M.gilvum_PYR-GCK          MHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEKMPRRFY
Mvan_0269|M.vanbaalenii_PYR-1       MHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVTLRDKMPRRFY
                                     **.*:* *   . .              * *      :          *

Mb2965c|M.bovis_AF2122/97           CYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDR
Rv2940c|M.tuberculosis_H37Rv        CYTRLTKAFNDGTRGGEADLDVLDEHGTVLLAVRGLRMGTGTSERDERDR
MLBr_00139|M.leprae_Br4923          CYTRLTKIE---PRGGEADLDVLDEHGAVLLAVRGLHMGTGTTERGELDR
MMAR_1767|M.marinum_M               CYTRVTKAD---ANGGEADLELLDEQGCVLLAVRGLRLGTGTSESGERDR
MUL_2010|M.ulcerans_Agy99           CYTRVTKAD---ANGGEADLELLDEQGCVLLAVRGLRLGTGTSESGERDR
MAV_2370|M.avium_104                CYTRVTKAD---TSGVEADIDVLDEHGAVLLAVQGLRVGTSASESGTRDR
TH_4621|M.thermoresistible__bu      CYARVTDAD---GSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDR
MSMEG_4727|M.smegmatis_MC2_155      CLSRIVKAD---SFGVEADLELLDADGTVLLSAMGLQLGTGNSDKAEEER
MAB_3148c|M.abscessus_ATCC_199      CYTRVTKVV---GNEVEADIDLLDETGSVLIAVRGFRFGTGSSDDEQRDQ
Mflv_0405|M.gilvum_PYR-GCK          CRATWHEAPLD-SETQVFDLEYLDRDGRHLGGVREFTVKRAPREALLRGL
Mvan_0269|M.vanbaalenii_PYR-1       CRATWHTSELD-SETQVFDLDFLDRDGRHLGGIREFTVKRAPREALLRGL
                                    * :               *:: **  *  *     : .  .  :      

Mb2965c|M.bovis_AF2122/97           LVSERLLTLGWQQRALPEVG---DGEAGSWLLIDTSNAVDTPDMLASTLT
Rv2940c|M.tuberculosis_H37Rv        LVSERLLTLGWQQRALPEVG---DGEAGSWLLIDTSNAVDTPDMLASTLT
MLBr_00139|M.leprae_Br4923          QLSERLLTIGWQQRTLPESV---HVEPGSWLLIDTFNASAIPDMWASTLT
MMAR_1767|M.marinum_M               VLSERLLTLEWQQRQLPEVL---DEETGSWLLIS---ASDGEDLMATMLA
MUL_2010|M.ulcerans_Agy99           VLSERLLTLEWQQRQLPEVL---DEETGSWLLIS---ASDGEDLMATTLA
MAV_2370|M.avium_104                VLTERLLNIEWRQRELPEP---EHADAASWLLIGTT-ATADV--LASTLA
TH_4621|M.thermoresistible__bu      VLGERLLTIEWQRRDLPEA---DSA-AGKWLLVSTS-ATADV--SATRLS
MSMEG_4727|M.smegmatis_MC2_155      LLDERLLTIEWQQRELPRPEGSETVDAGSWLVILAGDDDENP--RAAGVV
MAB_3148c|M.abscessus_ATCC_199      LLNNRLLAIEWQQQRLPES---VSGAPRRWLLVSTG-ESVDP--WAAELI
Mflv_0405|M.gilvum_PYR-GCK          GGDATRLLYTLGWHEVPVPE-----------------SGDGAAPQGTWLI
Mvan_0269|M.vanbaalenii_PYR-1       GGDATRLLYTLGWHEVPAPA-----------------SGD-AALNGNWLI
                                          *      : :*                            .  : 

Mb2965c|M.bovis_AF2122/97           DALKSHGPQGTECASLSWSVQDTPPNDQAGLEKLGSQLRGRD--GVVIVY
Rv2940c|M.tuberculosis_H37Rv        DALKSHGPQGTECASLSWSVQDTPPNDQAGLEKLGSQLRGRD--GVVIVY
MLBr_00139|M.leprae_Br4923          DALKSYGTQGTECTNLSWLIQDDP---VVSRERLGRQLRGRD--GVVILC
MMAR_1767|M.marinum_M               DALKS---QGAECASMVWSAQDDLAG---GIEKLGAQLRARTNKGVVIVC
MUL_2010|M.ulcerans_Agy99           DALKS---QGAECASMVWSAQDDLAG---GIEKLGAQLRARTNKGVVIVC
MAV_2370|M.avium_104                DTLKN---HGAQCTTMAWPQQADHTA---HAEQLRNQWRGDGFTGVVVLT
TH_4621|M.thermoresistible__bu      DALKQ---AGAESTSMCWPQQADHAD---NVDRFR-AGIADGVTGVVVLT
MSMEG_4727|M.smegmatis_MC2_155      SALIG---AGMPTTTMAWSHDADHDA---QAAALTARLDEQPLAGVAVIV
MAB_3148c|M.abscessus_ATCC_199      DSLKV---RESEVSLIQWRPNTDRVA---ALKLLYDQLESGTFDGVLVVT
Mflv_0405|M.gilvum_PYR-GCK          GGFDELAVSVPGCIPADR-TNPESLR----QLLTDAHGRGLPFSGVVWRA
Mvan_0269|M.vanbaalenii_PYR-1       AGFDELAAGVPGCIPFDRSTDPEPLG----QLLAQAHERGIGFSGVVWRA
                                      :                 :                       **    

Mb2965c|M.bovis_AF2122/97           GP-RVGDPDE----HSLLAGREQVRHLVRITRELAEFEGELPRLFVVTRQ
Rv2940c|M.tuberculosis_H37Rv        GP-RVGDPDE----HSLLAGREQVRHLVRITRELAEFEGELPRLFVVTRQ
MLBr_00139|M.leprae_Br4923          GP-RAGAPDE----QSLLAAREQVRHLVRIIRELAELEGELPRLFVVTRQ
MMAR_1767|M.marinum_M               GP-RSGDADE----QSLLQGREQVRHLVRITRELAELEGELPRLFVVTRQ
MUL_2010|M.ulcerans_Agy99           GP-RSGDADE----QSLLQGREQVRHLVRITRGLAELEGELPRLFVVTRQ
MAV_2370|M.avium_104                GP-KNGDNDQ----ESALLSRDHVQHLVRIARELTDLPGEPPRLYVVTRN
TH_4621|M.thermoresistible__bu      GP-KNGNPDD----AAARRGSDYVRHLVRITRELAEIDGDAPRLFVVTRG
MSMEG_4727|M.smegmatis_MC2_155      GD-SETGTDAHDVGADARRGADHVRHLVRIARTLADAVGEPPRLYVVTHR
MAB_3148c|M.abscessus_ATCC_199      APGSEGGADR-----VVLQGADQVRHLVRITRELVDLPGEPPRLFVVTRN
Mflv_0405|M.gilvum_PYR-GCK          ARSDGDESDA---EVAARLEAEIAELLGAVHTVQGGEVKLPGGLWIVTER
Mvan_0269|M.vanbaalenii_PYR-1       AAPSADESST---AMAARIETEIADLLSAVHTVQNGAVKLPGGLWIVTER
                                    .       .            : .  *  :             *::**. 

Mb2965c|M.bovis_AF2122/97           AQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVERV
Rv2940c|M.tuberculosis_H37Rv        AQIVKPHDSGERANLEQAGLRGLLRVISSEHPMLRTTLIDVDEHTDVERV
MLBr_00139|M.leprae_Br4923          AQIVQ---SGDAANLEQAGLRGLLRVISSEHPMLRTTLVDVDEHTDVERV
MMAR_1767|M.marinum_M               AQRVR---PEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDESTQAEQL
MUL_2010|M.ulcerans_Agy99           AQRVR---PEDEINLEQAGLRGLLRVIGSEHPLLQTTQVDVDESTQAEQL
MAV_2370|M.avium_104                AQTVLP---NDVPNLGQAGLRGLVRVIGMEHPQLGAGQIDVDESTDAQAL
TH_4621|M.thermoresistible__bu      AQAVLP---QDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRV
MSMEG_4727|M.smegmatis_MC2_155      SQHVLD---TDEPYLEHSGLRGLIRVVGMEHPRLRATQIDVDDSTAHEAL
MAB_3148c|M.abscessus_ATCC_199      AQTVVD---GDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHTAAQNV
Mflv_0405|M.gilvum_PYR-GCK          AVATES---GEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQA
Mvan_0269|M.vanbaalenii_PYR-1       AVATES---GEPVDPVQAALWGFGRTTINEEPALRCRLVDVDGSPEAVLA
                                    :  .      :     ::.* *: *.   * * *    :*    .     

Mb2965c|M.bovis_AF2122/97           AQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQ
Rv2940c|M.tuberculosis_H37Rv        AQQLLSGSEEDETAWRNGDWYVARLTPSPLGHEERRTAVLDPDHDGMRVQ
MLBr_00139|M.leprae_Br4923          AQQLLSGSEEDETAWRNGDWYVARLNPSPLSHEDRRTVVLNPEHDGLRVH
MMAR_1767|M.marinum_M               AQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTIVDHERDNMRLQ
MUL_2010|M.ulcerans_Agy99           AQQLLGGSEEDETAWRGGEWYVARLFPGPLSADERQTTVVDHERDNMRLQ
MAV_2370|M.avium_104                ARQLLAGSEEDETAWRDGAWYTARLCPAPLLPEERHTAVANHECDGMRLQ
TH_4621|M.thermoresistible__bu      AVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRLE
MSMEG_4727|M.smegmatis_MC2_155      VRQLLSGSPEDETAWRDGQWYAARLCPSPLRAAERRTAVADNASEGMRLV
MAB_3148c|M.abscessus_ATCC_199      AGELVSGSEEDETAWREDHWYRARLNLGPLGPDDWRSTVATPNNEGVRFE
Mflv_0405|M.gilvum_PYR-GCK          LAALLSTPVDE----PELAVRQGKLLASRLLPWSRSGHLTVPRGGDYVLA
Mvan_0269|M.vanbaalenii_PYR-1       LAGLLAAPVDE----PELAVRQGKLLASRLLPWARSGHLTVPRSADYVLA
                                       *:.   ::           .:*  . *        :      .  . 

Mb2965c|M.bovis_AF2122/97           VRRPGDLQTLEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIID
Rv2940c|M.tuberculosis_H37Rv        VRRPGDLQTLEFVASDRVPPGPGQIEVAVSMSSINFADVLIAFGRFPIID
MLBr_00139|M.leprae_Br4923          VRKPGDLQSLELVASDRVPPGPGQLEVAVSMSSINFADVLIAFGRFPIID
MMAR_1767|M.marinum_M               IRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIAFGRYPSLE
MUL_2010|M.ulcerans_Agy99           IRTPGDLQTLELAACDRVPPGPGQIEVAVTMSSINFADVLIAFGRYPSLE
MAV_2370|M.avium_104                IRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFGRYPAFE
TH_4621|M.thermoresistible__bu      IRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFADVLIAFGRYPTFD
MSMEG_4727|M.smegmatis_MC2_155      VRNPGDLESMELVTFERGTPGPGQIEVAVKASSINFADVLVAFGRCPSFD
MAB_3148c|M.abscessus_ATCC_199      VRTPGDLQSLGFVAFDRVAPGPGQIEVSVTATSINFADVLNVYGRYSSFE
Mflv_0405|M.gilvum_PYR-GCK          PTERGAIDNLRLTDSEVPPPAEGYVQVRVEAAGLNFRDVLNVLGLYP---
Mvan_0269|M.vanbaalenii_PYR-1       PTERGAIDNLRLTETDVAPPAEGYVQVRVEAAGLNFRDVLNVLGLYP---
                                        * ::.: :.  :  .*. * ::* *  :.:** *** . *  .   

Mb2965c|M.bovis_AF2122/97           DREPQLGMDFVGVVTAVGEGVTGHQVGDRVGGFSEGGCWRTFLTCDANLA
Rv2940c|M.tuberculosis_H37Rv        DREPQLGMDFVGVVTAVGEGVTGHQVGDRVGGFSEGGCWRTFLTCDANLA
MLBr_00139|M.leprae_Br4923          DRDPQLGMDFVGVVTAVGEGVTGHQIGDRVGGFSEGGCWRTFLTCDANLA
MMAR_1767|M.marinum_M               GRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSYLTCDANLA
MUL_2010|M.ulcerans_Agy99           GRLPETGTDFVGVVTAVGEGVTDHQVGDRVGGFSKDGCWRSYLTCDANLA
MAV_2370|M.avium_104                GRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCDARLA
TH_4621|M.thermoresistible__bu      GRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLA
MSMEG_4727|M.smegmatis_MC2_155      GRLPELGSEFGGVVTAVGPGVTTHRVGDRVGGVSANGCWSNFVTCEADLA
MAB_3148c|M.abscessus_ATCC_199      GRQ-ELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVDANLA
Mflv_0405|M.gilvum_PYR-GCK          GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQG-AFASRFNVPGQFL
Mvan_0269|M.vanbaalenii_PYR-1       GDPGPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQG-AFASRFNVPAQLL
                                    .     * :* *.** :* .**   :*::* *     .: . .   . : 

Mb2965c|M.bovis_AF2122/97           VTLPPGLTDEQAITAATAHATAWYGLNDLAQIKAGDKVLIHSATGGVGQA
Rv2940c|M.tuberculosis_H37Rv        VTLPPGLTDEQAITAATAHATAWYGLNDLAQIKAGDKVLIHSATGGVGQA
MLBr_00139|M.leprae_Br4923          VTLPSGLTDEQAITAATAHATAWYGLNDLAGIKVGDKVLIHSATGGVGQA
MMAR_1767|M.marinum_M               VTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHSATGGVGQA
MUL_2010|M.ulcerans_Agy99           VTLPAGLSDEHAAASSTAHATAWYGLNDLAGIKAGDRVLIHSATGGVGQA
MAV_2370|M.avium_104                VTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGGVGQA
TH_4621|M.thermoresistible__bu      VPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLA
MSMEG_4727|M.smegmatis_MC2_155      TKLPEGISEHEAAAVGLAYGTVWLGLTELARMSAGDKILIHSATGGVGQA
MAB_3148c|M.abscessus_ATCC_199      ATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGTGGVGQA
Mflv_0405|M.gilvum_PYR-GCK          APIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLIHAASGGVGLA
Mvan_0269|M.vanbaalenii_PYR-1       APIPDGIGAVDAATIPAAALTARLAF-DWAQLKPGDRVLIHAASGGVGLA
                                    . :*  :   .* :   *  *.  .: : * :  *:::***:.:**** *

Mb2965c|M.bovis_AF2122/97           AISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSVEFAEQIRRDTD
Rv2940c|M.tuberculosis_H37Rv        AISIARAKGAEIFATAGNPAKRAMLRDMGVEHVYDSRSVEFAEQIRRDTD
MLBr_00139|M.leprae_Br4923          AISIARAKGAEIFATAGNPTKRAMLHDLGIEHVYDSRSVEFAEQIRRDTD
MMAR_1767|M.marinum_M               AIAIARAAGAQIFATAGNAERRQLLNDMGIEHVYDSRSIEFADQIRRDTN
MUL_2010|M.ulcerans_Agy99           AIAIARAAGAQIFATAGNAERRQLVNDMGIEHVYDSRSIEFADQIRRDTN
MAV_2370|M.avium_104                AIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDTD
TH_4621|M.thermoresistible__bu      AIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRSTAFADEIRRDTD
MSMEG_4727|M.smegmatis_MC2_155      AIAVARAAGAEIYATAGSEKRRQLLRDWGIEHVYDSRTTAFADQIRTDTD
MAB_3148c|M.abscessus_ATCC_199      AIAIARAAGAEIYATAGSPERRDLLRSWGIKHVYDSRSTDFAELIRRDTD
Mflv_0405|M.gilvum_PYR-GCK          AVQMAQQCGAEVYATAS-TFKRATLRKLGVKHVYDSRTTDFAEQILADTD
Mvan_0269|M.vanbaalenii_PYR-1       AIQMAQQHGAVVFATAS-TYKRATLRKLGVDHVYDSRTTEFADQILADTD
                                    *: :*:  ** ::***.   :*  :.. *:.******:  **: *  **:

Mb2965c|M.bovis_AF2122/97           GYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR
Rv2940c|M.tuberculosis_H37Rv        GYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKADVYGNTRLGLFPFR
MLBr_00139|M.leprae_Br4923          GYGVDIVLNSLT-GAAQRAGLELLTFGGRFVEIGKADVYGNTRLGLFPFR
MMAR_1767|M.marinum_M               GYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKADVYGNTRMGLYPFR
MUL_2010|M.ulcerans_Agy99           GYGVDIVLNSLT-GAAQRAGLELLAFGGRFVEIGKADVYGNTRMGLYPFR
MAV_2370|M.avium_104                GYGVDIVLNSVT-GAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLLPFR
TH_4621|M.thermoresistible__bu      GYGVDVVLNSLP-GAAQRAGLELLSFGGRFIEIGKRDIYGDTRLGLFPFR
MSMEG_4727|M.smegmatis_MC2_155      GYGVDIVLNSVT-GPAQRAGLELLAFGGRFVEIGKRDIYADTRLGLFPFR
MAB_3148c|M.abscessus_ATCC_199      GYGVDIVLNSLT-GAAQRAGVELLTFGGRFIEIGKRDIYGDTRLGLFPFR
Mflv_0405|M.gilvum_PYR-GCK          GAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTVEQMAAA--R
Mvan_0269|M.vanbaalenii_PYR-1       GEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIAKRDIWTPEQMAAA--R
                                    * ***:****:.     .* :.  :  *** **.* *::   ::.    *

Mb2965c|M.bovis_AF2122/97           RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADG------VLTAPQCTH
Rv2940c|M.tuberculosis_H37Rv        RGLTFYYLDLALMSVTQPDRVRELLATVFKLTADG------VLTAPQCTH
MLBr_00139|M.leprae_Br4923          RGLTFYYLDLALMSVTQPDRVRELLATVFNLTADG------VLTAPECTH
MMAR_1767|M.marinum_M               RGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG------VLSAPECTH
MUL_2010|M.ulcerans_Agy99           RGLTFYYVDLGLMSVIQPERVRELLSTVYNLTAEG------VLSAPECTH
MAV_2370|M.avium_104                RNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADG------ALPMPESTH
TH_4621|M.thermoresistible__bu      RNLAFHGVDLGLMADSHPHKIRELLETVYRLTADG------VLPMPQSTH
MSMEG_4727|M.smegmatis_MC2_155      RNLSFYAVDLALMTVTHPQKIRDLLATVYRLIADG------TLPLPEITH
MAB_3148c|M.abscessus_ATCC_199      RNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEG------VLPLPEISP
Mflv_0405|M.gilvum_PYR-GCK          PDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDG------AWTPLPAEV
Mvan_0269|M.vanbaalenii_PYR-1       PDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGKADGSSRAEWVPLPAEI
                                     .:::  : *  :   .*. :   *  :     ..               

Mb2965c|M.bovis_AF2122/97           YPLAEAADAIRAMSNAEHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSY
Rv2940c|M.tuberculosis_H37Rv        YPLAEAADAIRAMSNAEHTGKLVLDVPRSGRRSVAVTPEQAPLYRRDGSY
MLBr_00139|M.leprae_Br4923          YPLTDAANAIRAMSNAEHTGKLVLDIPRTGSRSVAVPPEQAPVYRRDGSY
MMAR_1767|M.marinum_M               YPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVEVFRGDGSY
MUL_2010|M.ulcerans_Agy99           YPLAEAAEAIRTMSNAAHTGKLLLDMPRSGRRGVVVPPEQVEVFRGDGSY
MAV_2370|M.avium_104                YPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGAY
TH_4621|M.thermoresistible__bu      YPLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAY
MSMEG_4727|M.smegmatis_MC2_155      YPLEEAATAIRIMGGAQHTGKLVIDIPDTGQSQVVVPPEQVPVFRGDGAY
MAB_3148c|M.abscessus_ATCC_199      SPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGAY
Mflv_0405|M.gilvum_PYR-GCK          YPLTEARAAFRRMQQARHIGKIVVQIPNPLQP------------QPDRSY
Mvan_0269|M.vanbaalenii_PYR-1       YPLTEARAAFRRMQQARHVGKIVLQMPKPLQP------------RADRSY
                                     ** :*  ::* *  * * **:::::* .               : * :*

Mb2965c|M.bovis_AF2122/97           IITGGLGGLGLFFASKLAAAG----CGRIVLTARSQPNPKARQTIEGLRA
Rv2940c|M.tuberculosis_H37Rv        IITGGLGGLGLFFASKLAAAG----CGRIVLTARSQPNPKARQTIEGLRA
MLBr_00139|M.leprae_Br4923          IITGGLGGLGLFFASKLAEAG----CGRIVLTARSQPNPKARQTIERLCA
MMAR_1767|M.marinum_M               IITGGLGGLGLFFASKMAAAG----CGRIVLTARSQPNPKSRQAIERLRA
MUL_2010|M.ulcerans_Agy99           IITGGLGGLGLFFASKMAAAG----CGRIVLTARSQPNPKSRQAIERLRA
MAV_2370|M.avium_104                IVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALPNPKALATLERIRQ
TH_4621|M.thermoresistible__bu      IVTGGMGGLGLYLAGEMAAAG--AGC--IVLNGRSAPSGEALRTIEQLRA
MSMEG_4727|M.smegmatis_MC2_155      VITGGLGGLGLFLAERMAAAG----CGRIVVNSRSAPSTRSSEIIELIRA
MAB_3148c|M.abscessus_ATCC_199      VVTGGLGGLGLFLARKLAAAG----VGRIILNGRSAPKPEALAAIEQIRQ
Mflv_0405|M.gilvum_PYR-GCK          LITGGLGAIGLHTAGYLAQLG----AGDIVLTSRRAPDAAAQQAIADIAD
Mvan_0269|M.vanbaalenii_PYR-1       LITGGLGAIGLHTAAYLAQLG----AGDLVLTSRRAPDADARRAIEEITE
                                    ::***:*.:**. *  :*  *       ::: .*  *.  :   :  :  

Mb2965c|M.bovis_AF2122/97           -AGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAAVVEDATLTN
Rv2940c|M.tuberculosis_H37Rv        -AGADIVVECGNIAEPDTADRLVSAATATGLPLRGVLHSAAVVEDATLTN
MLBr_00139|M.leprae_Br4923          -AGADIVVECGNIAEPYTADRLVNAATATGLPLRGVLHSAAVVEDATLTN
MMAR_1767|M.marinum_M               -NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVEDATLSN
MUL_2010|M.ulcerans_Agy99           -NGADIVVECGNIAEPETADRLVSAATATGLPLRGVLHAAAVVEDATLSN
MAV_2370|M.avium_104                -MGADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLHLAAVIEDATLAN
TH_4621|M.thermoresistible__bu      -AGTEVIVECGXXXRG----QPVEVAVPT------ELRHADEHPDRRGAQ
MSMEG_4727|M.smegmatis_MC2_155      -TGADIVVECGDIAEPDTALRLVAAATQTGLPLRGVLHAAAVVEDATLAN
MAB_3148c|M.abscessus_ATCC_199      -GGTEIDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLAN
Mflv_0405|M.gilvum_PYR-GCK          RTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQ
Mvan_0269|M.vanbaalenii_PYR-1       RYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDALLSQ
                                         : .  .           :              : *    *   ::

Mb2965c|M.bovis_AF2122/97           ITDELIDR-DWSPKVFGSWNLHRATLGQP-----LDWFCLFSSGAALLGS
Rv2940c|M.tuberculosis_H37Rv        ITDELIDR-DWSPKVFGSWNLHRATLGQP-----LDWFCLFSSGAALLGS
MLBr_00139|M.leprae_Br4923          ITDELIDR-DWSPKVYGSWNLHCATIGQP-----LDWFCLFSSGAALLGS
MMAR_1767|M.marinum_M               ITDELIDR-DWSPKVYGSWNLHRASTGQP-----LDWFCLFSSGAALMGS
MUL_2010|M.ulcerans_Agy99           ITDELIDR-DWSPKVYGSWNLHRASTGQP-----LDWFCLFSSGAALMGS
MAV_2370|M.avium_104                ITDELIER-DWAAKVYGAWNLHCALQESG-AEQSLDWFCSFSSAAALVGS
TH_4621|M.thermoresistible__bu      LCDEFARG-EQGAQR----NQHRTDAGEG-QRD--------AHPPGAVGH
MSMEG_4727|M.smegmatis_MC2_155      ITDELVEH-DWAPKVYGAWNLHQAVQSGGPATSELDWFCAFSSAAALVGS
MAB_3148c|M.abscessus_ATCC_199      ITDELIDRGDWRPKVHGAWNLHEATADQP-----LDWFCSFSSIAALVGS
Mflv_0405|M.gilvum_PYR-GCK          QSVERFRT-ALAPKAFGAVHLDRLTRVDD-----LDFFLVSSSVSSLFGS
Mvan_0269|M.vanbaalenii_PYR-1       QSLERFRT-TLAPKAFGACHLDRLTAGDD-----LDFFIMSSSVSSLFGS
                                       *        .:     : .                   :  .. .* 

Mb2965c|M.bovis_AF2122/97           PGQGAYAAANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEI
Rv2940c|M.tuberculosis_H37Rv        PGQGAYAAANSWVDVFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEI
MLBr_00139|M.leprae_Br4923          PGQGAYAAANSWVDLFAHWRRAQGLPVSAIAWGAWGEVGRATFLAEGGEI
MMAR_1767|M.marinum_M               PGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEI
MUL_2010|M.ulcerans_Agy99           PGQGAYAAANSWVDAFAHWRRAQGLPVCAIGWGAWGEVGRATFLAEGGEI
MAV_2370|M.avium_104                PGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIGRGAALADSADV
TH_4621|M.thermoresistible__bu      DQPDPGALSDTGLDERGGQFPGVGVQIPVADPGVGIDH-RGAVRVDSGVP
MSMEG_4727|M.smegmatis_MC2_155      PGQGAYAAANSWLDAFMQWRRAQGLPATSIAWGAWGEIGRGTAMAE-GDN
MAB_3148c|M.abscessus_ATCC_199      PGQGAYAAANSWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNAEA
Mflv_0405|M.gilvum_PYR-GCK          PGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANI
Mvan_0269|M.vanbaalenii_PYR-1       PGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQGGMASSEAATANI
                                          * ::: :*       . *:       *       .:  .  .  

Mb2965c|M.bovis_AF2122/97           MIT---PEEGAYAFETLVRHDRAYSGYIPILGAPWLADL-----VRRSPW
Rv2940c|M.tuberculosis_H37Rv        MIT---PEEGAYAFETLVRHDRAYSGYIPILGAPWLADL-----VRRSPW
MLBr_00139|M.leprae_Br4923          MIT---PDEGAYAFEMLVRYDRPYSGYIPILGAPWLPDL-----VRRSPW
MMAR_1767|M.marinum_M               MIA---PDEGMYAFEQMLRHARTYTGYIPIIGAPWLADL-----VRRSPW
MUL_2010|M.ulcerans_Agy99           MIA---PDEGMYAFEQMLRHARTYTGYIPIIGAPWLADL-----VRRSPW
MAV_2370|M.avium_104                AIT---PDEGAYAFEALLRHDRACTGYAPITGTPWLTAF-----AQRSPF
TH_4621|M.thermoresistible__bu      AQQ---GVDGEVVRHRTLSSVRSGR-------SSRWTAP-----GSR--C
MSMEG_4727|M.smegmatis_MC2_155      AIA---PDEGAYAFEAILRHDRVYNGYAPVLGASWLTAF-----AQRSPF
MAB_3148c|M.abscessus_ATCC_199      AIL---PDEGAYAFDTVLRHNRAYTAYAPMAGISWLADF-----VERSPF
Mflv_0405|M.gilvum_PYR-GCK          SAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPIL
Mvan_0269|M.vanbaalenii_PYR-1       GAQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVLGSSRPPIL
                                            :   .                                     

Mb2965c|M.bovis_AF2122/97           GEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRRLLVEQASVILRRTID
Rv2940c|M.tuberculosis_H37Rv        GEMFASTGQRSRGPSKFRMELLSLPQDEWAGRLRRLLVEQASVILRRTID
MLBr_00139|M.leprae_Br4923          AEMFSSAGQGSRGPSKFRMELLALPQDEWSGRLRRLLVEQASVILRRTID
MMAR_1767|M.marinum_M               AEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQASVILRRTVD
MUL_2010|M.ulcerans_Agy99           AEMFQSSGQNTRGPSKFLAELKLLPQEEWAGRLRRLIAEQASVILRRTVD
MAV_2370|M.avium_104                AEAFRANGQSATGTSKLRAELEELPPEEWSTRLRRLISDQVSLILRRNVD
TH_4621|M.thermoresistible__bu      GSGRRYGGESCRRTTGPAAGAAARRGR-----------------TRRRRR
MSMEG_4727|M.smegmatis_MC2_155      AELFLADTQGASETRKLRSELAALPREEWPTHLRRLIAEQVGLLLRRTVD
MAB_3148c|M.abscessus_ATCC_199      AQAFRDAGQNQTETNKFLDELRALPREEWPTRLRKLVAEQVGLVLRRSID
Mflv_0405|M.gilvum_PYR-GCK          DLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQP
Mvan_0269|M.vanbaalenii_PYR-1       DLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREVQNFLRLAQP
                                                                                 *    

Mb2965c|M.bovis_AF2122/97           ADRS--FIEYGLDSLGMLEMRTHVETETGIRLTP--KVIATNNTARALAQ
Rv2940c|M.tuberculosis_H37Rv        ADRS--FIEYGLDSLGMLEMRTHVETETGIRLTP--KVIATNNTARALAQ
MLBr_00139|M.leprae_Br4923          ADRS--FIEYGLDSLGMLEMRTHIESETGIRLTP--KVIATNNTARALAQ
MMAR_1767|M.marinum_M               ADRP--FVEYGLDSLGMLEMRTHIETETGVRLSP--KVIASHNTARALSQ
MUL_2010|M.ulcerans_Agy99           ADRP--FVEYGLDSLGMLEMRTHIETETGVRLSP--KVIASHNTARALSQ
MAV_2370|M.avium_104                PDRP--LPEYGLDSLGGLELLTRIQTETGIRVSP--ADIAAIGTIRGLAD
TH_4621|M.thermoresistible__bu      PRRP--PPPP-----------DRVRHRAGP----------AHGPVRR---
MSMEG_4727|M.smegmatis_MC2_155      PDRP--LSEYGLDSLGHLELRTRIETETGVRVS-----AMDMTTIRGLAQ
MAB_3148c|M.abscessus_ATCC_199      PDRS--LPDYGLDSLGNLEIRTRIQADTGVRIG-----PADVSTVRSLAA
Mflv_0405|M.gilvum_PYR-GCK          PAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAE
Mvan_0269|M.vanbaalenii_PYR-1       PAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAE
                                    .  .                  ::.   *              .      

Mb2965c|M.bovis_AF2122/97           YLADTLAEEQAAAPAAS--------------------
Rv2940c|M.tuberculosis_H37Rv        YLADTLAEEQAAAPAAS--------------------
MLBr_00139|M.leprae_Br4923          YLADTLAEEEGVAAPAAMVSPETP-------------
MMAR_1767|M.marinum_M               HLADTLAEEEAQPAAS---------------------
MUL_2010|M.ulcerans_Agy99           HLADTLAEEEAQPAAS---------------------
MAV_2370|M.avium_104                LLRDKLTPAGAAQAERV--------------------
TH_4621|M.thermoresistible__bu      -------------------------------------
MSMEG_4727|M.smegmatis_MC2_155      RLCEMLDTDDAVSAPS---------------------
MAB_3148c|M.abscessus_ATCC_199      HIYDRLAEQESEVASS---------------------
Mflv_0405|M.gilvum_PYR-GCK          YLVAQLPD-----AETPQAAPQSESEPGPDVTE----
Mvan_0269|M.vanbaalenii_PYR-1       YLVGQLPDSDAAAGETPATETSPIDHNHPDREADSPG