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MPGKGIRAGEGTPLGIITRAATPLILAIASLCALVATPAVAAPDALSAAVDSAFRPLLVQYDIPGMAVAV TVNGQQRYFNYGVAAKQSGAPVTADTIFEIGSVSKTFTATLACYAQELGRISLAGHPSAYMPQLAGSAID KATLLNLGTYTAGGLPLQFPPEITDDAQMQAYFQQWAPDDAPGQQRRYSNPSIGLLGHLTALAMNSDFAD LVQTQVFPKLGLSHSFIRVPQAQMDDYAWGYNASNEPVRVNPGVFAAEAYGVKSSAPDMLRFVEANISPE GLPASMRRAVQATHLGYFNVADMVQGLGWEQYSYPVTLDQLLAGNSNTIAMQPNPVTPVAGVPPSGPRLF NKTGSTDGFGAYAAFVPDKRIGIVMLANKNFPNAARITAAHAVLEKLAAESR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1674 | ampC | - | 100% (402) | penicillin-binding protein |
M. marinum M | MMAR_2827 | - | 3e-11 | 29.68% (219) | lipoprotein |
M. marinum M | MMAR_0696 | lpqK | 4e-08 | 24.19% (215) | lipoprotein, LpqK |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1759c | - | 1e-15 | 27.24% (312) | penicillin-binding protein |
M. gilvum PYR-GCK | Mflv_1757 | - | 6e-06 | 25.94% (293) | beta-lactamase |
M. tuberculosis H37Rv | Rv1730c | - | 1e-15 | 27.24% (312) | penicillin-binding protein |
M. leprae Br4923 | MLBr_00119 | lipE | 1e-05 | 27.21% (136) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_1801 | - | 5e-13 | 24.86% (362) | bacteriophage protein |
M. avium 104 | MAV_3395 | - | 7e-10 | 27.56% (225) | beta-lactamase |
M. smegmatis MC2 155 | MSMEG_3978 | ampC | 1e-130 | 62.83% (374) | beta-lactamase |
M. thermoresistible (build 8) | TH_0147 | - | 4e-17 | 26.10% (249) | POSSIBLE PENICILLIN-BINDING PROTEIN |
M. ulcerans Agy99 | MUL_4410 | - | 2e-05 | 24.78% (226) | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE |
M. vanbaalenii PYR-1 | Mvan_3027 | - | 1e-12 | 26.25% (259) | Serine-type D-Ala-D-Ala carboxypeptidase |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 MPRSFDRIPLPFNDPNQGLEFHIGTAFQQGLEMWKAIIDGIIEYAESLIK Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 ELIQKLLGLDVDPEQALEDLWNLLTGWVDDIPIIGDIIEIIKDFLNGNLF Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 GRDGFILSNLIPALSFSWITDEQPNLLVAGNFQDGSSIADNPYWTWESGV Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 THSADSSGSVKVTANGVTKALRSNEILANPGQTMSLEMWVKWSGYAGTNS Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 PIKLQMVEFSGRGDSAVQVGVEDVATLNPNTSTGDWRQMVGNYTVPDGVH Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 AVRVRILVTKDATSGVFNFDDGVGKKTNKIQQGWIDGLSNTFQEVLSRWQ Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 LIIDTVVNGITGSNNALHTLEDLFDAVTHIPLFKILGFGGPGDANTTFEE Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 FLSHLLGGMSGSTDPNSNGGFADLFNVAKLLQTAAAMGESAFQILSIRNN Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 TPVNTGLLPSGRSNYGLTSVNTTLSATQSASLIATMRVEQDIALGVVSWL Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------MGETYESVTVEIKDQVAQATLIGPG Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 GCGTSGITAFYVNIWKLDGVSGDWALVHHSPNILSELTAGTTPNWTFYQL Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 KGNAMGPAFWSELPEVFAALDADRDVRAIVITGSGKNFSYGLDVPAMGGT Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 DTPVDQKAGEIYAYELVPVGGTHSVRGISTTDDIPDHPFAQVVGLAATRD Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 FAPLMAEGALARPRTDFHAEVLRMQKATNAVADCRTPTIASVHGWCIGGG Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 NSSSPNTPPSTIAKASVVRSGNIPWIETAIDTGNGVGYYDPISVYAVDDG Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 VDLISAVDMRYASADAKFSIREVKLAIVADMGSLARLPMILNDGHLRELA Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 TIPIPSWCNFVDVVAVGGAGGGQMGFTVGFHGEPGSPGLYKAATWQRGVH Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 LTGRDIDAARAEKIGLVNQVFEDADATLAAAHATATEIAANPPLAVYGVK Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 FADDTVLTFTKGPGGLGGRLGHDDGEDGTATSWSIPDYSITAEPGIGGTE Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 DVLDQQRASAVAENLRYVAAWNAAFLPSKDLTEGISATFAKRPPQFTGEQ Mb1759c|M.bovis_AF2122/97 ---------------------------------------------MCPPI Rv1730c|M.tuberculosis_H37Rv ---------------------------------------------MCPPI TH_0147|M.thermoresistible__bu -------------------------------------------------M MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 ----------------------------------------------MADE MAB_1801|M.abscessus_ATCC_1997 LQLGYNPIGRGPGNFEYKGENHVGGADQKIPGRDGVSPGGGGNGGNGLTF Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 ------------MTSDGKIRVPTDLDAVTAIGDEDHSDIDSA----AVER MUL_4410|M.ulcerans_Agy99 AAASTYPRGVASMTEDGRIRVPADLDAVTALGAEDHSEIDSA----AIER Mb1759c|M.bovis_AF2122/97 ILSSATPTGTRCGTRHGRAVVTEYVRALDRLP----HEIATA----VVET Rv1730c|M.tuberculosis_H37Rv ILSSATPTGTRCGTRHGRAVVTEYVRALDRLP----HEIATA----VVET TH_0147|M.thermoresistible__bu RLS------RRSMLRATGGVVAGALLAGAVSG----ATTGCG----RRED MMAR_1674|M.marinum_M ---------MPGKGIRAGEGTPLGIITRAATPLILAIASLCA----LVAT MSMEG_3978|M.smegmatis_MC2_155 ------------------------MFT--AGRICAALIVLVA----LISA MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 NGRRDSAHTLGAMITRALPIVFAMVLALTACGESVDTTQTTGSRNPAVTA MAB_1801|M.abscessus_ATCC_1997 QNGGKGADGAGWVRFRQNPLEGEEVIGGPGQVLVPSIESTAS---LGTPT Mflv_1757|M.gilvum_PYR-GCK MKSRVGAVALVMAVALLAGCAAESTEPAASSTPAPGPLSDVPPPLVPAMP MLBr_00119|M.leprae_Br4923 IWQATRHWYQAGMHPAIQLCIRQHGRVVLNRAIGHG----WGNAPTDPHD MUL_4410|M.ulcerans_Agy99 IWQATRYWYQAGMHPAIQLCIRHNGRVVLNRAIGHG----WGNAPSDAPD Mb1759c|M.bovis_AF2122/97 VNCADPGAAFDELDAKINAGMKAYAIPGVAVAVWAGG-QEYVKGYGVTNV Rv1730c|M.tuberculosis_H37Rv VNCADPGAAFDELDAKINAGMKAYAIPGVAVAVWAGG-QEYVKGYGVTNV TH_0147|M.thermoresistible__bu SDSGDR--LFAELDAKIQDLMDRHGVPGVAVGVWHDG-VEHLRGFGVTNV MMAR_1674|M.marinum_M PAVAAPDALSAAVDSAFRPLLVQYDIPGMAVAVTVNG-QQRYFNYGVAAK MSMEG_3978|M.smegmatis_MC2_155 APTASADP-SAAVARAFAPLLDQYDVPGMAVAVTVDG-RQHFYEFGVVSK MAV_3395|M.avium_104 -------MTLDANSVSIREVCDAGLLAGAVTMVWQRGELLQVNEIGYRDV Mvan_3027|M.vanbaalenii_PYR-1 PATTMAAEVTDRLDDAVERVMTEAGIPGAIVGIWGPG-GDYVRAFGVADT MAB_1801|M.abscessus_ATCC_1997 VSGGLSLLPLEDQAAIDAIVAANMTAPGGVLAIQSPD-GYYTKAYGKVST Mflv_1757|M.gilvum_PYR-GCK LPENAVANAVAKLDGLAEDLMSTSGVPGMAVAVVHQGKTVYAKGFGVKNN : MLBr_00119|M.leprae_Br4923 AEKIP----VTTDTPFCAYSAAKAITATVVHMLVERGHFSLDDRVCEYLP MUL_4410|M.ulcerans_Agy99 AEKIP----VSTDTPFCTYSSAKAITATVVHMLAERGHFSLDDRVCEYIP Mb1759c|M.bovis_AF2122/97 DHPMP----VDGDTVFRIGSTTKTFTGTVMMRLVERGKVDLDSPVRRYIP Rv1730c|M.tuberculosis_H37Rv DHPMP----VDGDTVFRIGSTTKTFTGTVMMRLVERGKVDLDSPVRRYIP TH_0147|M.thermoresistible__bu DDPEP----VTPDTLFRIGSTTKTFTGTTVMRLVEAGRIDLDERVRTYLP MMAR_1674|M.marinum_M QSGAP----VTADTIFEIGSVSKTFTATLACYAQELGRISLAGHPSAYMP MSMEG_3978|M.smegmatis_MC2_155 QTQAP----VTRDTLFEIGSVSKTFTATLAGYAATRGVLNLDDHPGRYLP MAV_3395|M.avium_104 EAGLP----MRRDTLFRIASMTKPVTVAAVMSLVDAGKLSLKDPVTRWAP Mvan_3027|M.vanbaalenii_PYR-1 KTRAP----MKTDFYSRIGSLTKTFTVTAVLLLADQGRLGLDDPIAGYVD MAB_1801|M.abscessus_ATCC_1997 AAGARN---VIPEDHFRIGSCTKSFTATMILQAVDRGLLSLDDPLEKFLP Mflv_1757|M.gilvum_PYR-GCK TQSDSPENRVDADTVFQLASLSKPLSATVVAALVGQDQVGWDTPVVSRLP : : * :*..: : . .. MLBr_00119|M.leprae_Br4923 TYTSYGK---------------HRTTIRHVLTHSAGVPFPTGPR------ MUL_4410|M.ulcerans_Agy99 SYTSHGK---------------DHTTIRHVLTHSAGVPFPTGPR------ Mb1759c|M.bovis_AF2122/97 DFAVADESAS------------ATVTVRQLLNHTAGWDGRNGQD------ Rv1730c|M.tuberculosis_H37Rv DFAVADESAS------------ATVTVRQLLNHTAGWDGRNGQD------ TH_0147|M.thermoresistible__bu DFTTADPTVA------------ERVTVRQLLNHTPGWHGDYFVD------ MMAR_1674|M.marinum_M QLAGSAI---------------DKATLLNLGTYTAGGLPLQFPP------ MSMEG_3978|M.smegmatis_MC2_155 ALAGTPI---------------DRAELRNLGTYTAGGLPLQFPE------ MAV_3395|M.avium_104 ELAGVRVLDDPHGPLDRTHPLDRAILIEDLLTHTSGLAYGFSVSGPISKA Mvan_3027|M.vanbaalenii_PYR-1 GVPGGDA-----------------ITLRQLARMQSGLPDYTANPEFVPTV MAB_1801|M.abscessus_ATCC_1997 GVPGGTK-----------------ITVRHMMCLRSGLFNEQTDLGMMMRY Mflv_1757|M.gilvum_PYR-GCK WFALSDPTTT------------QMVTVGDMFSHRSGLPDHAGDQ------ . : .: .* MLBr_00119|M.leprae_Br4923 -PDVTRADDHAYAQQKLSELRPFYRPGLVHIYHALTWGPLMREIIWTATG MUL_4410|M.ulcerans_Agy99 -PDVTRADDHDYAARKLGELRPLYPPGLVHIYHALTWGPLMREIIWATTR Mb1759c|M.bovis_AF2122/97 -FGRG-DDAVALYVKAMTRLPQLTPPGTAFAYNNSGL-VVAGRIIELVAG Rv1730c|M.tuberculosis_H37Rv -FGRG-DDAVALYVKAMTRLPQLTPPGTAFAYNNSGL-VVAGRIIELVAG TH_0147|M.thermoresistible__bu -TGSG-EDALAKYVAAIATLPQQTPLGTTFAYNNAAI-ALAGRIIEAVTG MMAR_1674|M.marinum_M -EITD----DAQMQAYFQQWAPDDAPGQQRRYSNPSI-GLLGHLTALAMN MSMEG_3978|M.smegmatis_MC2_155 -SVTD----DEQMIAYFQQFQPVTAPGKIRQYSNPSV-GLLGHISARALG MAV_3395|M.avium_104 YMRLPFQHGPDAWLAELAKLPLVHQPGEKVTYSHSID--LLGVIAARIED Mvan_3027|M.vanbaalenii_PYR-1 IADPGRAFAPTEMLEFAFSQPPMFAPGDGYHYSNTNT-VLLGLVVEKVSG MAB_1801|M.abscessus_ATCC_1997 FLMPTSDWTDEETLAIVKQHEPSFEPGQGWAYVNSNY-FLLGMIVSIVNG Mflv_1757|M.gilvum_PYR-GCK --LEDLGYDRRQVLDRLRQLP-LAQFRTSYAYTNFGL-TAGAEAVATGAG * MLBr_00119|M.leprae_Br4923 KEIRDILAAEILDPLGFRWTNFGVAEEDVPLVALSH--ATGRPLPP---- MUL_4410|M.ulcerans_Agy99 KEIRDILATEILDPLGFRWTNFGVAEEDLPLVAPSH--ATGRPLPP---- Mb1759c|M.bovis_AF2122/97 TTYESTVQRLLLDPLQLAHTRYFSDQIIGLNVAASHSVVDGKPIAV---- Rv1730c|M.tuberculosis_H37Rv TTYESTVQRLLLDPLQLAHTRYFSDQIIGLNVAASHSVVDGKPIAV---- TH_0147|M.thermoresistible__bu TGYERVVRTELLEPLGLQHTGFSVDNLEGPPVAEPHTMADGAPRFD---- MMAR_1674|M.marinum_M SDFADLVQTQVFPKLGLSHSFIRVPQAQMDDYAWGYN-ASNEPVRV---- MSMEG_3978|M.smegmatis_MC2_155 GQFTDLMQSQILTGLGLRRSFVDVTDEAMDFYAWGYD-KKNHPVRV---- MAV_3395|M.avium_104 KPFHQVLDERVLGPAGMTDTGFFVSPQARHRAATMYSLDEHSRLQHGVMG Mvan_3027|M.vanbaalenii_PYR-1 QSLGDYIRRHISAPLGMAETSFPTDATFPGPHATGYTVQPPDDREM---- MAB_1801|M.abscessus_ATCC_1997 RPTRDVLQTDILDPLGLTQTSWPTTAKMPEPYANGHAWATGIFGGG-AWQ Mflv_1757|M.gilvum_PYR-GCK KSWEDLAADTLLRPLGMGVTSYRFEDYASRRDRAVGHIRIDDGYQP---- : : : MLBr_00119|M.leprae_Br4923 IIAAIFRKAIG------GTVHEVIPYTNTPPFLTTIVPSSNTVSTAN--- MUL_4410|M.ulcerans_Agy99 VIAAAFRKAIG------GTVHEVIPYTNKPLFLRTIIPSSNTVSTAN--- Mb1759c|M.bovis_AF2122/97 TDFWTFPRSCNPTGGLMSTARDQLRYAQFHLGDGRAPNGEQILSRQSLKA Rv1730c|M.tuberculosis_H37Rv TDFWTFPRSCNPTGGLMSTARDQLRYAQFHLGDGRAPNGEQILSRQSLKA TH_0147|M.thermoresistible__bu RSAWYMPRCLNPTGGLISTARDQLRYARFHLGDGGGLPDLGLLSEESLTA MMAR_1674|M.marinum_M NPGVFAAEAYG----VKSSAPDMLRFVEANISPEGLPASMRRAVQAT--- MSMEG_3978|M.smegmatis_MC2_155 NPGVFDAEAYG----VKSTTADMIRFIEHNIDPGALEPTLREAVKST--- MAV_3395|M.avium_104 PPHVTPPAFCNAGGGLWSSADDYLRFVRMLLGDG-TIDGVRVLSEES--- Mvan_3027|M.vanbaalenii_PYR-1 -----------------TATDWNLSWSWAAGNMVSTLHDLRIWAPAL--- MAB_1801|M.abscessus_ATCC_1997 DATETGPGYASAAGVMISTAHDLLLWAKELRDGTLLSPELHELRTKCYWP Mflv_1757|M.gilvum_PYR-GCK -RYVRDAQAQSPAGGASSSVNDMTRWMAMVLAEGRHDGNALIDPQALLPA :. : MLBr_00119|M.leprae_Br4923 -------------ELSRFAEIWLR---GGELDGIRVLRSETLLGAVAECR MUL_4410|M.ulcerans_Agy99 -------------ELSRFMEILRR---GGELDGVRIMAPETVRSAVTECR Mb1759c|M.bovis_AF2122/97 MRSNPGAGGTLWVELTGMGVTWML---RPSAENVTIVEHGGTWKGQRSGF Rv1730c|M.tuberculosis_H37Rv MRSNPGAGGTLWVELTGMGVTWML---RPSAENVTIVEHGGTWKGQRSGF TH_0147|M.thermoresistible__bu MRSDPGPGGTLAVEIDGMGVTWHL---RPSAEGVHIVQHGGAWSGQHSGF MMAR_1674|M.marinum_M -----------HLGYFNVADMVQG---LGWEQYSYPVTLDQLLAGNSNTI MSMEG_3978|M.smegmatis_MC2_155 -----------QVGYYKVGPMVQD---LGWEQYPYPVALDQLLAGNSGEM MAV_3395|M.avium_104 --------------VRLMRTDRLT---EAQKRHNFLGAPYWVGRGFGLNL Mvan_3027|M.vanbaalenii_PYR-1 ----------------VTGTLLSR---QMQQQRLQMVESSGQPAPEEYGL MAB_1801|M.abscessus_ATCC_1997 VPWGNDDQLTYFGYGHGMFELGQW---RGHGGSWRGYEVSVYYLPNGTLF Mflv_1757|M.gilvum_PYR-GCK ISPQVTSAPPTEPAMRPGFYGYGFNVGTTSAARTQLSHSGAFELGAATNV MLBr_00119|M.leprae_Br4923 RLRPDFVVGLMPARWGTG-------FILGTNKFGPFG--RNAPAAFGHLG MUL_4410|M.ulcerans_Agy99 RLRPDSATGLAPLRWGTG-------FMLGSNRFGPFG--RNAPAAFGHLG Mb1759c|M.bovis_AF2122/97 VMVPDRNFAMTVLTNSDGGFHMINDLFASDWALQRFAGLSNLPATPQRLG Rv1730c|M.tuberculosis_H37Rv VMVPDRNFAMTVLTNSDGGFHMINDLFASDWALQRFAGLSNLPATPQRLG TH_0147|M.thermoresistible__bu YLVPDRDFAMTVLTNSDGGAMLVADLMYTDWALDHFAGLHNLPAPVRDLS MMAR_1674|M.marinum_M AMQPNPVTPVAGVPPSGPR------LFNKTGSTDGFG-AYAAFVPDKRIG MSMEG_3978|M.smegmatis_MC2_155 AMSPQAATAIA-PPSVGSA------LFNKTGSTDGFG-AYAAFVPERRIG MAV_3395|M.avium_104 SVVTDPARSIPLFGPGGVG------TFSWPGAYGTWWQADPTAELILIYL Mvan_3027|M.vanbaalenii_PYR-1 GMFNVAG------------------WIGHNGSVPGYQ-TVSVYLPERQTA MAB_1801|M.abscessus_ATCC_1997 AMCENAQTPTVEVEVSMMFKIG-KYLYPDSLTVPDYQANRVFGIPSKASV Mflv_1757|M.gilvum_PYR-GCK LFLPSADVAIIALTNATPTG-VPETLTAQFADLVQFGEIRQDWAALYGKA . : MLBr_00119|M.leprae_Br4923 --------LVNIAIWADPQRSMAAGLISSGKPGQDPNAGRYGALMNTITA MUL_4410|M.ulcerans_Agy99 --------LVNIATWADPDRGLSVGLINSGKPGRDPDAKRYVALKNAITA Mb1759c|M.bovis_AF2122/97 --------AVDLAPYEGRYIAKQVAQNGDLETTVIDFRARDGQLAGSMST Rv1730c|M.tuberculosis_H37Rv --------AVDLAPYEGRYIAKQVAQNGDLETTVIDFRARDGQLAGSMST TH_0147|M.thermoresistible__bu --------PAELADYEGRYHAYETGVDGSVDATDTVLTADRGRLRYQMLS MMAR_1674|M.marinum_M --------IVMLANKNFPNAARITAAHAVLEKLAAESR------------ MSMEG_3978|M.smegmatis_MC2_155 --------IVMLANKNFPIPARVTAAHTVLDALDA--------------- MAV_3395|M.avium_104 --------IQNLPDLTVDAATAVAGNTSLAKLRTAQPRFVRTTYRALGL- Mvan_3027|M.vanbaalenii_PYR-1 --------LVILTNTDIAFRGAEPGTLLARAVTTELTPDHVYTLS----- MAB_1801|M.abscessus_ATCC_1997 GKPIVGSIDVKFDNKSTLGTSQATIPEFTLDPEANIVFAYLATQSGIDLS Mflv_1757|M.gilvum_PYR-GCK FAD----MDKPVGSLVGQQRHVNAQTHGPLDSYTGVYGNDYWGPATVTER . MLBr_00119|M.leprae_Br4923 EIPVH--------------------------------------------- MUL_4410|M.ulcerans_Agy99 EIPPKTVE------------------------------------------ Mb1759c|M.bovis_AF2122/97 DDANP--DGQNSANLGLAFYRPDYGLDLGPDNKPTGSRSNFVRGPDGNIA Rv1730c|M.tuberculosis_H37Rv DDANP--DGQNSANLGLAFYRPDYGLDLGPDNKPTGSRSNFVRGPDGNIA TH_0147|M.thermoresistible__bu DDGAPVTDPPPGTPAYLAFYRDDYVLQLDRDGEPLPSRADFVRDDTGQVR MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 VVTAKIGGVTMNRLPIMSNGSNQLVVWWLLDPPTGARSINLLNAPYGSNY Mflv_1757|M.gilvum_PYR-GCK DGRLQLALGPRGVFELDAWDGNVFVFPVSSENAPPGTVSAATFDGGALTL MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 WFCSQHGRLFRRQ------------------------------------- Rv1730c|M.tuberculosis_H37Rv WFCSQHGRLFRRQ------------------------------------- TH_0147|M.thermoresistible__bu WLR-IGGRLHRKTA------------------------------------ MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 ATGAASYKLAAPAGIETPVITQGYSASPSVSATTNSHGRIVNAFLYGGQT Mflv_1757|M.gilvum_PYR-GCK EYFDQEGNGVFVR------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MUL_4410|M.ulcerans_Agy99 -------------------------------------------------- Mb1759c|M.bovis_AF2122/97 -------------------------------------------------- Rv1730c|M.tuberculosis_H37Rv -------------------------------------------------- TH_0147|M.thermoresistible__bu -------------------------------------------------- MMAR_1674|M.marinum_M -------------------------------------------------- MSMEG_3978|M.smegmatis_MC2_155 -------------------------------------------------- MAV_3395|M.avium_104 -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 SAYNQTERGHLDAVAFGAGLIFGDAPGGSVTFTQTLTAAAPWIGIAIPIV Mflv_1757|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00119|M.leprae_Br4923 ---- MUL_4410|M.ulcerans_Agy99 ---- Mb1759c|M.bovis_AF2122/97 ---- Rv1730c|M.tuberculosis_H37Rv ---- TH_0147|M.thermoresistible__bu ---- MMAR_1674|M.marinum_M ---- MSMEG_3978|M.smegmatis_MC2_155 ---- MAV_3395|M.avium_104 ---- Mvan_3027|M.vanbaalenii_PYR-1 ---- MAB_1801|M.abscessus_ATCC_1997 SNAE Mflv_1757|M.gilvum_PYR-GCK ----