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VPRSFDRIPLPFNDPNQGLEFHIGTAFQQGLEMWKAIIDGIIEYAESLIKELIQKLLGLDVDPEQALEDL WNLLTGWVDDIPIIGDIIEIIKDFLNGNLFGRDGFILSNLIPALSFSWITDEQPNLLVAGNFQDGSSIAD NPYWTWESGVTHSADSSGSVKVTANGVTKALRSNEILANPGQTMSLEMWVKWSGYAGTNSPIKLQMVEFS GRGDSAVQVGVEDVATLNPNTSTGDWRQMVGNYTVPDGVHAVRVRILVTKDATSGVFNFDDGVGKKTNKI QQGWIDGLSNTFQEVLSRWQLIIDTVVNGITGSNNALHTLEDLFDAVTHIPLFKILGFGGPGDANTTFEE FLSHLLGGMSGSTDPNSNGGFADLFNVAKLLQTAAAMGESAFQILSIRNNTPVNTGLLPSGRSNYGLTSV NTTLSATQSASLIATMRVEQDIALGVVSWLGCGTSGITAFYVNIWKLDGVSGDWALVHHSPNILSELTAG TTPNWTFYQLDTPVDQKAGEIYAYELVPVGGTHSVRGISTTDDIPDHPFAQVVGLAATRDNSSSPNTPPS TIAKASVVRSGNIPWIETAIDTGNGVGYYDPISVYAVDDGTIPIPSWCNFVDVVAVGGAGGGQMGFTVGF HGEPGSPGLYKAATWQRGVHFADDTVLTFTKGPGGLGGRLGHDDGEDGTATSWSIPDYSITAEPGIGGTE LQLGYNPIGRGPGNFEYKGENHVGGADQKIPGRDGVSPGGGGNGGNGLTFQNGGKGADGAGWVRFRQNPL EGEEVIGGPGQVLVPSIESTASLGTPTVSGGLSLLPLEDQAAIDAIVAANMTAPGGVLAIQSPDGYYTKA YGKVSTAAGARNVIPEDHFRIGSCTKSFTATMILQAVDRGLLSLDDPLEKFLPGVPGGTKITVRHMMCLR SGLFNEQTDLGMMMRYFLMPTSDWTDEETLAIVKQHEPSFEPGQGWAYVNSNYFLLGMIVSIVNGRPTRD VLQTDILDPLGLTQTSWPTTAKMPEPYANGHAWATGIFGGGAWQDATETGPGYASAAGVMISTAHDLLLW AKELRDGTLLSPELHELRTKCYWPVPWGNDDQLTYFGYGHGMFELGQWRGHGGSWRGYEVSVYYLPNGTL FAMCENAQTPTVEVEVSMMFKIGKYLYPDSLTVPDYQANRVFGIPSKASVGKPIVGSIDVKFDNKSTLGT SQATIPEFTLDPEANIVFAYLATQSGIDLSVVTAKIGGVTMNRLPIMSNGSNQLVVWWLLDPPTGARSIN LLNAPYGSNYATGAASYKLAAPAGIETPVITQGYSASPSVSATTNSHGRIVNAFLYGGQTSAYNQTERGH LDAVAFGAGLIFGDAPGGSVTFTQTLTAAAPWIGIAIPIVSNAE
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1801 | - | - | 100% (1374) | bacteriophage protein |
M. abscessus ATCC 19977 | MAB_0330 | - | 7e-50 | 35.50% (338) | Beta-lactamase |
M. abscessus ATCC 19977 | MAB_2833 | - | 1e-12 | 26.82% (358) | beta-lactamase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0405c | lpqK | 4e-24 | 28.90% (301) | lipoprotein LpqK |
M. gilvum PYR-GCK | Mflv_3749 | - | 2e-09 | 27.23% (224) | beta-lactamase |
M. tuberculosis H37Rv | Rv0399c | lpqK | 4e-24 | 28.90% (301) | lipoprotein LpqK |
M. leprae Br4923 | MLBr_00119 | lipE | 3e-07 | 28.03% (157) | putative hydrolase |
M. marinum M | MMAR_3882 | - | 2e-24 | 31.09% (267) | bacteriophage membrane protein |
M. avium 104 | MAV_0791 | - | 3e-10 | 28.99% (207) | hypothetical protein MAV_0791 |
M. smegmatis MC2 155 | MSMEG_3378 | - | 6e-44 | 35.51% (321) | beta-lactamase |
M. thermoresistible (build 8) | TH_3520 | - | 1e-43 | 34.69% (320) | PUTATIVE beta-lactamase |
M. ulcerans Agy99 | MUL_3735 | lipP | 5e-10 | 29.24% (171) | esterase/lipase LipP |
M. vanbaalenii PYR-1 | Mvan_3027 | - | 2e-45 | 34.52% (336) | Serine-type D-Ala-D-Ala carboxypeptidase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 MPRSFDRIPLPFNDPNQGLEFHIGTAFQQGLEMWKAIIDGIIEYAESLIK Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M -------------------------------------------------- MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 ELIQKLLGLDVDPEQALEDLWNLLTGWVDDIPIIGDIIEIIKDFLNGNLF Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M -------------------------------------------------- MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 GRDGFILSNLIPALSFSWITDEQPNLLVAGNFQDGSSIADNPYWTWESGV Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M -------------------------------------------------- MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 THSADSSGSVKVTANGVTKALRSNEILANPGQTMSLEMWVKWSGYAGTNS Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M ----------MSPPGFGGAPYSSPQERTLTAITDGREQTPKSAEEISRML MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 PIKLQMVEFSGRGDSAVQVGVEDVATLNPNTSTGDWRQMVGNYTVPDGVH Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M QTQQAQIRFLASNQKQMQKGINEATQNPIQQMQQFISDLIVLFGGGQLAQ MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 AVRVRILVTKDATSGVFNFDDGVGKKTNKIQQGWIDGLSNTFQEVLSRWQ Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M GVLDFGDLTYILPALGALFGFGDGPFPLNLIAAAEKFFFGYVVPTQAFTD MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 LIIDTVVNGITGSNNALHTLEDLFDAVTHIPLFKILGFGGPGDANTTFEE Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M LLNHFIGTWLEAFGIDEKFVADVKDLVTAVGELFDGVTGLLPNVNEFFGA MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 FLSHLLGGMSGSTDPNSNGGFADLFNVAKLLQTAAAMGESAFQILSIRNN Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M LGITAAGLGPLGLALAPIIKLFEAIDIKKFGNAVEFITDAIDPWIVQLTQ MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 TPVNTGLLPSGRSNYGLTSVNTTLSATQSASLIATMRVEQDIALGVVSWL Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M IINFTNAVLHILGSGEDVLNSPLPQLTAPWANLIKFLGGINFAIANFNPL MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 GCGTSGITAFYVNIWKLDGVSGDWALVHHSPNILSELTAGTTPNWTFYQL Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M AAAQQFIGRLLIPLGGISEVQPDLQLDSSFD--ESSSIAEDSPAWAPQDL MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 DTPVDQKAGEIYAYELVPVGGTHSVRGISTTDDIPDHPFAQVVGLAATRD Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M DPLVDYPEGWLWDLVGRNAPGSATVDCDGANHALLGTEIPVVEG------ MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 NSSSPNTPPSTIAKASVVRSGNIPWIETAIDTGNGVGYYDPISVYAVDDG Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M ---QTFAPECWLTWSGVAAAGSTFRLQVMTDGGSATDIAAVSSPAASAGW MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 TIPIPSWCNFVDVVAVGGAGGGQMGFTVGFHGEPGSPGLYKAATWQRGVH Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M THLSGTYTVPAGVATIRTRLYVSGNATAGQVWFDDAPIRRTNLMQKGFIQ MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 FADDTVLTFTKGPGGLGGRLGHDDGEDGTATSWSIPDYSITAEPGIGGTE Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M GLVDDLTELFGNFAAMIDGILGTGHTFSDLVTFIASGLSLAAEAADNFTA MAV_0791|M.avium_104 -------------------------------------MAVTFDSSTTAIA MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -----------------------------------------MADENGRRD Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 LQLGYNPIGRGPGNFEYKGENHVGGADQKIPGRDGVSPGGGGNGGNGLTF Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M LLSGLSLANITSLVSFLDTASSNAVDAIGALGDLVANALQVDAAGVGTLI MAV_0791|M.avium_104 SIAGSATTGSTPATTHNVSRSAPNPAVIAAVEWVGTVDASGATFAVEFGG MSMEG_3378|M.smegmatis_MC2_155 ---------MRAARTSATILLAILAL---------------VVPPPVTAQ TH_3520|M.thermoresistible__bu ---------MRAVRTLAALLLAVFAV---------------SAGPSAAGQ Mvan_3027|M.vanbaalenii_PYR-1 SAHTLGAMITRALPIVFAMVLALTACGESVDTTQTTGSRNPAVTAPATTM Mb0405c|M.bovis_AF2122/97 ---------MPVLRRLGCSVLALGLLAG--------CAPPRTGPASSPTN Rv0399c|M.tuberculosis_H37Rv ---------MPVLRRLGCSVLALGLLAG--------CAPPRTGPASSPTN MAB_1801|M.abscessus_ATCC_1997 QNGGKGADGAGWVRFRQNPLEGEEVIGGPGQVLVPSIESTASLGTPTVSG Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------MTSDGKIRVPTDLDAVTAIGD---------EDHSDIDSAAVER MMAR_3882|M.marinum_M ASLLTMLTQISDIFNGSVVTPVNTVVQQIKDWWAATGENIPNAISDVGTI MAV_0791|M.avium_104 QAMTPVPEAQAFWHSNTGMVQLFYLLNPPTGAQTVTASVTGMGTESGART MSMEG_3378|M.smegmatis_MC2_155 PLELAARLDRAIEARLAQMGAPGAIVSLSI-PGEIDYVKTFGAGDTATGV TH_3520|M.thermoresistible__bu PPDLAAALDRAIELRLDQMGVPGAIVSLSI-PGKIEYTRAFGVGDTATGT Mvan_3027|M.vanbaalenii_PYR-1 AAEVTDRLDDAVERVMTEAGIPGAIVGIWG-PGG-DYVRAFGVADTKTRA Mb0405c|M.bovis_AF2122/97 NGAKADAVIRIVRDFMTQAHLKAVLVRVTV-AGKEVVTRAVG--DSMTGV Rv0399c|M.tuberculosis_H37Rv NGAKADAVIRIVRDFMTQAHLKAVLVRVTV-AGKEVVTRAVG--DSMTGV MAB_1801|M.abscessus_ATCC_1997 GLSLLPLEDQAAIDAIVAANMTAPGGVLAIQSPDGYYTKAYGKVSTAAGA Mflv_3749|M.gilvum_PYR-GCK ---MNLDRNKASIVDAIDAGLLAGAVTLVWHAGEVRQVNELGYRDVDAQL MUL_3735|M.ulcerans_Agy99 ---------------------MEVGAAVAVWVDGDLVVNLWGGSADAAGT MLBr_00119|M.leprae_Br4923 IWQATRHWYQAGMHPAIQLCIRQHGRVVLNRAIGHGWGNAPTDPHDAEKI MMAR_3882|M.marinum_M ISSAGQTLASAVGTAIQNAGAALDDVKNNVIGGATNAVTVWGQAWEGAFA MAV_0791|M.avium_104 LALATASYSGVAGVGSGTTASGASAALAVTSPTAPLFVNAFGCTVAAGGD MSMEG_3378|M.smegmatis_MC2_155 P---MLVDNHHRIGSVTKTFTGTAILQLVEQGRIRLSDPISRYVEG---- TH_3520|M.thermoresistible__bu P---MLVDNHHRIGSVTKTFIGTAILQLADQGRIRLSDPISRYVEG---- Mvan_3027|M.vanbaalenii_PYR-1 P---MKTDFYSRIGSLTKTFTVTAVLLLADQGRLGLDDPIAGYVDG---- Mb0405c|M.bovis_AF2122/97 P---ATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRWLPD---- Rv0399c|M.tuberculosis_H37Rv P---ATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRWLPD---- MAB_1801|M.abscessus_ATCC_1997 RN--VIPEDHFRIGSCTKSFTATMILQAVDRGLLSLDDPLEKFLPG---- Mflv_3749|M.gilvum_PYR-GCK P---MQRDTIFRIASMTKPVTVAAAMSLVEEGRLSLTDRVATWLPELADM MUL_3735|M.ulcerans_Agy99 RP--WRQDTLTTVLSGSKALTATCVHQLADRGELNLHAPVARYWPEFR-- MLBr_00119|M.leprae_Br4923 P---VTTDTPFCAYSAAKAITATVVHMLVERGHFSLDDRVCEYLPTYT-- MMAR_3882|M.marinum_M G---FFNSISGASVAAAQTGQVSSAMTSQRETIVGISTAVAQLQAAAAAS MAV_0791|M.avium_104 SFASYNQTSRANIASVASTNQPLLIGDAAGSGLVDFTATAPAASEEWAGL : : . . : MSMEG_3378|M.smegmatis_MC2_155 -------------VPSGDVITLDLLGRMRSGLIDYTET-GDFIERLYRES TH_3520|M.thermoresistible__bu -------------VPSGDVITLDMLARMRSGLADYTET-DEFVERLYRES Mvan_3027|M.vanbaalenii_PYR-1 -------------VPGGDAITLRQLARMQSGLPDYTAN-PEFVPTVIADP Mb0405c|M.bovis_AF2122/97 -------------FPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANP Rv0399c|M.tuberculosis_H37Rv -------------FPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANP MAB_1801|M.abscessus_ATCC_1997 -------------VPGGTKITVRHMMCLRSGLFNEQTDLGMMMRYFLMPT Mflv_3749|M.gilvum_PYR-GCK RVLAEPRGALDRTVPAQRHITIEDLMTHRSGLAYMFSVLGPLSDAYRKLP MUL_3735|M.ulcerans_Agy99 -------------QAGKEAITVAMVLSHRSGVIGPNAR-------MSWQQ MLBr_00119|M.leprae_Br4923 -------------SYGKHRTTIRHVLTHSAGVPFPTGP--------RPDV MMAR_3882|M.marinum_M G---------SSGVFGGDDFEREDLDDLGSDWAVTYSGGDSSDGYVAIAN MAV_0791|M.avium_104 G-----------VGLLGNAISFDAVGTDAAGYLAEGSIAHTLAADATALL : :. MSMEG_3378|M.smegmatis_MC2_155 PKGPDAF------------AVTPRELVESAFAQPLKFTPGSRYEY--SNT TH_3520|M.thermoresistible__bu PSGPDAF------------AVTPRELVESAFARPLNFAPGSEFEY--SNT Mvan_3027|M.vanbaalenii_PYR-1 GR-----------------AFAPTEMLEFAFSQPPMFAPGDGYHY--SNT Mb0405c|M.bovis_AF2122/97 FR-----------------QWTTQELLDQISSRPLLYDPGTNWNY--AHT Rv0399c|M.tuberculosis_H37Rv FR-----------------QWTTQELLDQISSRPLLYDPGTNWNY--AHT MAB_1801|M.abscessus_ATCC_1997 SD------------------WTDEETLAIVKQHEPSFEPGQGWAY--VNS Mflv_3749|M.gilvum_PYR-GCK TR------------------QDQDRWLTELSALPLVHQPGERLTY--SHA MUL_3735|M.ulcerans_Agy99 VT-------------------DWDFVCEQLALAEPRWEPGSAQGYH-MTT MLBr_00119|M.leprae_Br4923 TR-----------------ADDHAYAQQKLSELRPFYRPGLVHIYH-ALT MMAR_3882|M.marinum_M GHQAAWETGDAVTRSVFCRRTASADQHTQTNYQKIRWTVGAIPDVP-SNG MAV_0791|M.avium_104 AAVNIYN-------------TAAVTLTAEVGSKPMTLLASETYGLYSSNP . MSMEG_3378|M.smegmatis_MC2_155 NTVLLG--MVVEKVSGVPLGQYLQDNIFGPVGLSQTSYPG---------- TH_3520|M.thermoresistible__bu NTVLLG--MVVERVSGVPLARYLQDNIFGPVGLTQTSYPA---------- Mvan_3027|M.vanbaalenii_PYR-1 NTVLLG--LVVEKVSGQSLGDYIRRHISAPLGMAETSFPT---------- Mb0405c|M.bovis_AF2122/97 NYLLLG--LALEKAAGQDMPTLLQRKVLSPLGLTATANSD---------- Rv0399c|M.tuberculosis_H37Rv NYLLLG--LALEKAAGQDMPTLLQRKVLSPLGLTATANSD---------- MAB_1801|M.abscessus_ATCC_1997 NYFLLG--MIVSIVNGRPTRDVLQTDILDPLGLTQTSWPT---------- Mflv_3749|M.gilvum_PYR-GCK -TDVLG--IALSRIEGKPLSEVLAERIFEPLGMTDTGFSV---------- MUL_3735|M.ulcerans_Agy99 FGFILG--EVFRRITGRTVGQYLRTEIAEPIGADVHIGLSPFD------- MLBr_00119|M.leprae_Br4923 WGPLMR--EIIWTATGKEIRDILAAEILDPLGFRWTNFGVAEED------ MMAR_3882|M.marinum_M GDPVYT--RLYFRVSDDESSYSFVEIRNENNGFGGDNTWVQFGYKNGGPE MAV_0791|M.avium_104 WLYPFGSLYLFGVIDPPVGAQTIKVNSSAPVYMTAQSVSYIG-------- : MSMEG_3378|M.smegmatis_MC2_155 --------NGWLPGPYAHGYN-RAPNDAIVDT--------TLWNPSWADA TH_3520|M.thermoresistible__bu --------DGRLPAPYTHGYN-QGPDGAIVDT--------TLWNPAWADA Mvan_3027|M.vanbaalenii_PYR-1 --------DATFPGPHATGYTVQPPDDREMTA--------TDWNLSWSWA Mb0405c|M.bovis_AF2122/97 --------TPAIPEPALHAFTSERRAALKIPAGVPFYEESTFWNPSWTIT Rv0399c|M.tuberculosis_H37Rv --------TPAIPEPALHAFTSERRAALKIPAGVPFYEESTFWNPSWTIT MAB_1801|M.abscessus_ATCC_1997 --------TAKMPEPYANGHAWATGIFGGGAWQD-----ATETGPGYASA Mflv_3749|M.gilvum_PYR-GCK --------GSEGRRRAATMYQLDKDGTLRHDVMG----PAPIVDPPFCTG MUL_3735|M.ulcerans_Agy99 --------QSRCAERVNKPHARDLLADVQAPSDPTSLDDHPKAGLSIAMG MLBr_00119|M.leprae_Br4923 --VPLVALSHATGRPLPPIIAAIFRKAIGGTVHEVIPYTNTPPFLTTIVP MMAR_3882|M.marinum_M TYVGSPILTSYISGFNFTLYAGNPDTFERYYELIRLGSSVATWDDTSTEY MAV_0791|M.avium_104 --------ALGFDTPVSSNGALNQLTAPSTKPAARLVAAHGITPRANAFG MSMEG_3378|M.smegmatis_MC2_155 AGKIVSN-VHDMRTWTKVLGSGALLQPDTHAQRISNG--------SEVVP TH_3520|M.thermoresistible__bu AGKIVSN-VHDMRTWARALGSGALLRPDTHAERIHGG--------SSVVP Mvan_3027|M.vanbaalenii_PYR-1 AGNMVST-LHDLRIWAPALVTGTLLSRQMQQQRLQMVE-------SSGQP Mb0405c|M.bovis_AF2122/97 HGAIQTTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRG----KTRAQP Rv0399c|M.tuberculosis_H37Rv HGAIQTTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRG----KTRAQP MAB_1801|M.abscessus_ATCC_1997 AGVMIST-AHDLLLWAKELRDGTLLSPELHELRTKCYWPV----PWGNDD Mflv_3749|M.gilvum_PYR-GCK GAGLFSTVDDYLRFARMLLNGGTLDGTRVLSEDSAMSMRT----DRLTAE MUL_3735|M.ulcerans_Agy99 FAPDDELGSNDLHLWRQLEFPGTNAQVSALGLATFYNALA----QEKLLS MLBr_00119|M.leprae_Br4923 SSNTVSTANELSRFAEIWLRGGELDGIRVLRSETLLGAVA----ECRRLR MMAR_3882|M.marinum_M SAVGASNLGWGFGLQAAAAPGGVAQAAPASLDSITIADNGPGAFDYASLP MAV_0791|M.avium_104 YNQTKRAIVNSSSADQILLLGDAAGAPYVVSAASMSAYTP---AWGAVAV . MSMEG_3378|M.smegmatis_MC2_155 G----------VDYAFTIFDVQ----GWRGHNGDIPGYATVAVYLP-QRD TH_3520|M.thermoresistible__bu G----------VDYSFAIFNAQ----GWLGHNGDIPGYATVVVYLP-ERD Mvan_3027|M.vanbaalenii_PYR-1 AP---------EEYGLGMFNVA----GWIGHNGSVPGYQTVSVYLP-ERQ Mb0405c|M.bovis_AF2122/97 GCPTCFEQNDGYSYGLGIVISG----HWLLQNPMFAGYAAVEAYLPSQRV Rv0399c|M.tuberculosis_H37Rv GCPTCFEQNDGYSYGLGIVISG----HWLLQNPMFAGYAAVEAYLPSQRV MAB_1801|M.abscessus_ATCC_1997 QLT-------YFGYGHGMFELG----QWRGHGGSWRGYEVSVYYLPNGTL Mflv_3749|M.gilvum_PYR-GCK QKR--------QDFLGAPFWIG----RGFGLNLSVVTDPAKSRQLFGPGG MUL_3735|M.ulcerans_Agy99 REHMDLVRVSQGGFDTDLVLGP----RVADHGWGLGYMLNQRAVNGPNQK MLBr_00119|M.leprae_Br4923 P-----------DFVVGLMPAR----WGTGFILGTNKFGPFG-----RNA MMAR_3882|M.marinum_M DFGNPGRRYPCQDIGLELLDTGSEWLRINGGPRGWFTPPPDTGWSPVNAG MAV_0791|M.avium_104 NLLPAPVTLNVSAVIGPIVGSASLADYRVHTPSPLRTYSVPVGSTEVVTS . MSMEG_3378|M.smegmatis_MC2_155 ATLVVFVNSDVPEPHSAG--QIADVVTTIATPDHVYAVGPQPPLMLEDTD TH_3520|M.thermoresistible__bu ATLVVFVNSDVPEPHSAG--QIAYVVTEMVTPEHIYELGPQPPQMLDEPA Mvan_3027|M.vanbaalenii_PYR-1 TALVILTNTDIAFRGAEPGTLLARAVTTELTPDHVYTLS----------- Mb0405c|M.bovis_AF2122/97 AVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPNDAPPMPPGR---- Rv0399c|M.tuberculosis_H37Rv AVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPNDAPPMPPGR---- MAB_1801|M.abscessus_ATCC_1997 FAMCENAQTPTVEVEVSMMFKIGKYLYPDSLTVPDYQANRVFGIPSKASV Mflv_3749|M.gilvum_PYR-GCK LGTFSWPGAYGTWWQADPSADVILIYLIQNLPSMSVDVAAAIAGNTSLAK MUL_3735|M.ulcerans_Agy99 IFGHGGLGGSFGFVDLEHRIGYAYVMNRFDASKANADPRSVALSNEVYAA MLBr_00119|M.leprae_Br4923 PAAFGHLGLVNIAIWADPQRSMAAGLISSGKPGQDPNAGRYGALMNTITA MMAR_3882|M.marinum_M STTFSASKDGLLFISPSDPSGSYHLQVRTLSPASNYTAEFYVEMTAMDAA MAV_0791|M.avium_104 FGRVGPTWTQAADAVLDYTFDFTNWLAGTGDSVAAATFTPVSPGLTVVSV . MSMEG_3378|M.smegmatis_MC2_155 DRPAG--------------------------------------------- TH_3520|M.thermoresistible__bu A------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 GKPIVGSIDVKFDNKSTLGTSQATIPEFTLDPEANIVFAYLATQSGIDLS Mflv_3749|M.gilvum_PYR-GCK LQTAQPKFVRSTYQALEL-------------------------------- MUL_3735|M.ulcerans_Agy99 LDVAAD-------------------------------------------- MLBr_00119|M.leprae_Br4923 EIPVH--------------------------------------------- MMAR_3882|M.marinum_M GSDAWVMGIILRESSSQKFVTLEQVVSSNAFGSGALIRAAKWTN------ MAV_0791|M.avium_104 NVTTAQATGWLTGGVTGDVYPVIVHIVTEYGRQYDQTFNLIVQQT----- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 VVTAKIGGVTMNRLPIMSNGSNQLVVWWLLDPPTGARSINLLNAPYGSNY Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M --TTTLSAAYKARYVQFLSGAFPNWIRFRDNGTTRYFEYSHNGVEWLTFY MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 ATGAASYKLAAPAGIETPVITQGYSASPSVSATTNSHGRIVNAFLYGGQT Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M SVGRTDFCTPDQIGVGVFNVVTGFTNHLRIRSLEGVS------------- MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 -------------------------------------------------- TH_3520|M.thermoresistible__bu -------------------------------------------------- Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0405c|M.bovis_AF2122/97 -------------------------------------------------- Rv0399c|M.tuberculosis_H37Rv -------------------------------------------------- MAB_1801|M.abscessus_ATCC_1997 SAYNQTERGHLDAVAFGAGLIFGDAPGGSVTFTQTLTAAAPWIGIAIPIV Mflv_3749|M.gilvum_PYR-GCK -------------------------------------------------- MUL_3735|M.ulcerans_Agy99 -------------------------------------------------- MLBr_00119|M.leprae_Br4923 -------------------------------------------------- MMAR_3882|M.marinum_M -------------------------------------------------- MAV_0791|M.avium_104 -------------------------------------------------- MSMEG_3378|M.smegmatis_MC2_155 ---- TH_3520|M.thermoresistible__bu ---- Mvan_3027|M.vanbaalenii_PYR-1 ---- Mb0405c|M.bovis_AF2122/97 ---- Rv0399c|M.tuberculosis_H37Rv ---- MAB_1801|M.abscessus_ATCC_1997 SNAE Mflv_3749|M.gilvum_PYR-GCK ---- MUL_3735|M.ulcerans_Agy99 ---- MLBr_00119|M.leprae_Br4923 ---- MMAR_3882|M.marinum_M ---- MAV_0791|M.avium_104 ----