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MPNYVTTMPHGNPPGAVSAVTGDGSVVEIYRRMPSLGEVERIHSLLPPRSSVLDLGAGTGRIANALTALG HRVTAVDDSAEMLEHVRCARTVQARIENLRLAERFDAVLLISNLINYPDTQLLRSMLASVTHHLAPAGKA IIEWSPPSYFAERPTGWTGTHVKAGVTMSLAIHSNRGGVIDAELVVAVDDQQWCQRQTMRRITLATLRRE LARAGLVLTTAAPESTRWLQVKTRHEPERTVRAFPLGRGPGVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1596 | - | - | 100% (253) | hypothetical protein MMAR_1596 |
| M. marinum M | MMAR_4482 | - | 2e-54 | 51.64% (213) | methyltransferase |
| M. marinum M | MMAR_1164 | - | 2e-07 | 25.86% (116) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 5e-06 | 32.28% (127) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_3090 | - | 1e-07 | 34.55% (110) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3342 | - | 5e-06 | 32.28% (127) | methyltransferase (methylase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2548c | - | 3e-08 | 26.09% (115) | hypothetical protein MAB_2548c |
| M. avium 104 | MAV_4332 | - | 9e-07 | 27.27% (165) | SAM-dependent methyltransferases |
| M. smegmatis MC2 155 | MSMEG_3430 | - | 8e-07 | 26.96% (115) | SAM-dependent methyltransferase |
| M. thermoresistible (build 8) | TH_1247 | - | 3e-07 | 24.14% (116) | SAM-dependent methyltransferase |
| M. ulcerans Agy99 | MUL_2851 | - | 1e-07 | 25.86% (116) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1534 | - | 2e-06 | 22.96% (135) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4332|M.avium_104 MVEQSIWMQKVAADPGHSHWYIERFRAMARAGDDLAGEARFVDAMAPRG-
Mvan_1534|M.vanbaalenii_PYR-1 MVETSIWMQKVAADPGHSRWYIERFRAMARAGDDLAGEARLVDAMAPRG-
MUL_2851|M.ulcerans_Agy99 MVEQSIWMQKVAADPGHSRWYIERFRAMARAGEDLVGEARLVDSIAPRG-
MSMEG_3430|M.smegmatis_MC2_155 MVEQSLWMQKVAADPGHSQWYIERFRSLARAGEDLFGEARLVDAMAPRN-
TH_1247|M.thermoresistible__bu MVEKSLWMRKVEADPGHSQWYIERFRAMARAGEDLVGEARLVDAMAPRN-
MAB_2548c|M.abscessus_ATCC_199 MVEQSLWMQKVAADPNHSQWYIDRFRSMARDGADLAGEARLVDALVPRG-
Mflv_3090|M.gilvum_PYR-GCK --MSTRWQQ---SDRPRGEDYDARWKRLAASGASVHGEADLIEALLREGG
Mb3374|M.bovis_AF2122/97 ---------MTCSRRDMSLSFGSAVGAYERGRPSYPPEA--IDWLLPAAA
Rv3342|M.tuberculosis_H37Rv ---------MTCSRRDMSLSFGSAVGAYERGRPSYPPEA--IDWLLPAAA
MMAR_1596|M.marinum_M MPNYVTTMPHGNPPGAVSAVTGDGSVVEIYRRMPSLGEVERIHSLLPPR-
. . *. :. :
MAV_4332|M.avium_104 -ARILDAGCGPGRLGSYLAAAGHQVVGVDVDPALIEAAEHDHPGPRWLVG
Mvan_1534|M.vanbaalenii_PYR-1 -ARILDAGCGPGRVGGYLAAAGHQVVGVDVDPALIEAAEQDYPGPRWLVG
MUL_2851|M.ulcerans_Agy99 -AHILDAGCGPGRLGRHLAAAGHRVVGVDVDPALIEAAEQDYPGPQWLVG
MSMEG_3430|M.smegmatis_MC2_155 -AHILDAGCGPGRLGGYLAGVGHRVVGVDVDPALIAAAEEDYPGPRWLVG
TH_1247|M.thermoresistible__bu -AHILDAGCGPGRLGGYLSAAGHRVVGVDVDPALIEAAEQDYPGPQYLVG
MAB_2548c|M.abscessus_ATCC_199 -ARILDAGCGAGRVGGFLAAAGHHVVGVDVDPALIEAAEHDHPGPRWLVG
Mflv_3090|M.gilvum_PYR-GCK GTRVLDAGCGTGRVAIELAARGFDVVGLDADPTMLETARAKAPRLRWIEA
Mb3374|M.bovis_AF2122/97 -RRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLG
Rv3342|M.tuberculosis_H37Rv -RRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLG
MMAR_1596|M.marinum_M -SSVLDLGAGTGRIANALTALGHRVTAVDDSAEMLEHVRCARTVQARIEN
:** *.*.*:: * * *..:* . :: . . :
MAV_4332|M.avium_104 DLAELDLP------------------ARGITDPFDVIVSAGNV-MTFLAP
Mvan_1534|M.vanbaalenii_PYR-1 DLAELDLP------------------ARGITEPFDLIVSAGNV-MTFLAP
MUL_2851|M.ulcerans_Agy99 DLAELDLP------------------ARGIAEPFDVIVSAGNV-MTFLAP
MSMEG_3430|M.smegmatis_MC2_155 DLAELDLP------------------ARGIAEPFDIIVSAGNV-MTFLAP
TH_1247|M.thermoresistible__bu DLAELDLP------------------ARGIPDPFDVIVMAGNV-MAFLAP
MAB_2548c|M.abscessus_ATCC_199 DLAELDLP------------------SRGISEPFDVIVSAGNV-MAFLAP
Mflv_3090|M.gilvum_PYR-GCK DLVDTDD---------------------HLDETFDVVALPGNV-MIFLDR
Mb3374|M.bovis_AF2122/97 TAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTR
Rv3342|M.tuberculosis_H37Rv TAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTR
MMAR_1596|M.marinum_M LRLAERFDAVLLISNLIN-YPDTQLLRSMLASVTHHLAPAGKAIIEWSPP
: . : *. : :
MAV_4332|M.avium_104 STRVLVLSRLRAHLAADGR----AAIGFGAYR-EYEFTDFLNDAADAGFA
Mvan_1534|M.vanbaalenii_PYR-1 STRVQVLARLRAHLRDDGR----AVIGFGAGR-EYEYPQFLDDAAAGGLT
MUL_2851|M.ulcerans_Agy99 STRARVLGRLRAHLCSDGR----AVIGFGAGR-DYAFADFLDDAQAAGLV
MSMEG_3430|M.smegmatis_MC2_155 STRAQVLSRLRAHLTDNGR----AVIGFGAGR-DYGFEEFLADAKGAGFT
TH_1247|M.thermoresistible__bu STRTTVLSRLRAHLAEDGR----AAIGFGAGR-DYDFDEFLADAATAGLT
MAB_2548c|M.abscessus_ATCC_199 STRRQVLRRLRSHLADPGR----AVIGFGAGR-DYEFSEFLSDADAAGLV
Mflv_3090|M.gilvum_PYR-GCK GTEAAVVAALARRLAPGGL----LVAGFQLGTGRLTLDRYDEITATAALE
Mb3374|M.bovis_AF2122/97 DERLGWVRELGEIIGRDGD----PVRDRVTLPEPFTTVQRHQVEWTNYLT
Rv3342|M.tuberculosis_H37Rv DERLGWVRELGEIIGRDGD----PVRDRVTLPEPFTTVQRHQVEWTNYLT
MMAR_1596|M.marinum_M SYFAERPTGWTGTHVKAGVTMSLAIHSNRGGVIDAELVVAVDDQQWCQRQ
. * .
MAV_4332|M.avium_104 PDLLLSSWDLRPFTEDSDFLVAVLRPA-----------------------
Mvan_1534|M.vanbaalenii_PYR-1 PDLLLSTWDVRPFTDDSDFLVAVLRPA-----------------------
MUL_2851|M.ulcerans_Agy99 PDLLLSTWDLRPFTDDCDFLVALLRPA-----------------------
MSMEG_3430|M.smegmatis_MC2_155 PDQLLSTWDVRPFSEDSDFLVAILRRA-----------------------
TH_1247|M.thermoresistible__bu PDLLLSTWDLRPFTEDSEFLVALLRRA-----------------------
MAB_2548c|M.abscessus_ATCC_199 PDLLLSTWDLRPFTDKSDFLVALLRRDDAPS-------------------
Mflv_3090|M.gilvum_PYR-GCK LVDRWATWDRQPY-DGGDYAVSLHRLT-----------------------
Mb3374|M.bovis_AF2122/97 PQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYV
Rv3342|M.tuberculosis_H37Rv PQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYV
MMAR_1596|M.marinum_M TMRRITLATLRRELARAGLVLTTAAPESTRWLQVKTRHEPERTVRAFPLG
: :
MAV_4332|M.avium_104 ---------
Mvan_1534|M.vanbaalenii_PYR-1 ---------
MUL_2851|M.ulcerans_Agy99 ---------
MSMEG_3430|M.smegmatis_MC2_155 ---------
TH_1247|M.thermoresistible__bu ---------
MAB_2548c|M.abscessus_ATCC_199 ---------
Mflv_3090|M.gilvum_PYR-GCK ---------
Mb3374|M.bovis_AF2122/97 TVCVRATLA
Rv3342|M.tuberculosis_H37Rv TVCVRATLA
MMAR_1596|M.marinum_M RGPGVA---