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VNFAVLSPEANSARILSGPGPGPLLAAAAAWDGIGQELAAAASAFSSLTSDLAGAAWQGPSAAAMASVAT SYVRWLGSAASGAVQTARQAATSAAVFEAARTATVPLELVAANRSALMSMVAANVFGLNAPAIAAIEAQY EQMWAQNVGAMFGYHVGVSEALSGLAPWQEVLSGVSGRVASALEGTSAAAAAALGPTALTAAGSALPAAA TDVTLVIGGSGFPIPSQSYVDNVVNNFVTPNFPSFTVSNAISLFTPAESYWITGIKTMTEDASWAEGLTI LDTAIKAQLAAGNNVVVQGYSQGAGIASLEMSNLKAAGVPTGSVSFSLIGNAMNPNGGLYERFAGLVSPS LGKTFWGATPDNYYTTDVYTLEYDGFADFPRYPLNFVSDLNAIMGIYYVHTQYPTLTAAQVATAFTLPTE GATMTTYHMIPTENLPLLEPLRGVPFIGNTLADLVQPDLKVLVNLGYGDPNYGYSTGPANVPTPFGLFPD VAPATVFDALVAGTQQGISDAAADIGAWQLPSLPDISLSGISNALGSDPWSALSNATLPTLSVSTIENAI KGVQTATTDIANTISFDATTAYATLLPTADVVNAMVTTLPAYNLKLFLDGILQVLDGDPAGLIYALGAPI AADTALVTLLAGFNLYAYLYAFNKILPGVL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1497 | - | - | 100% (660) | PPE family protein, PPE28 |
M. marinum M | MMAR_1027 | - | e-171 | 51.25% (642) | PPE family protein |
M. marinum M | MMAR_4321 | - | e-132 | 46.11% (592) | PE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1828 | PPE28 | 1e-172 | 51.76% (653) | PPE family protein |
M. gilvum PYR-GCK | Mflv_1918 | - | 2e-28 | 30.52% (367) | hypothetical protein Mflv_1918 |
M. tuberculosis H37Rv | Rv1800 | PPE28 | 1e-173 | 52.07% (653) | PPE family protein |
M. leprae Br4923 | MLBr_01182 | - | 3e-31 | 31.48% (359) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_0809c | - | 4e-25 | 36.88% (160) | PPE family protein |
M. avium 104 | MAV_4704 | - | 4e-53 | 52.15% (209) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_5455 | - | 2e-32 | 31.15% (366) | PE family protein |
M. thermoresistible (build 8) | TH_3724 | - | 1e-34 | 39.34% (272) | PUTATIVE putative PE-PPE, C-terminal domain protein |
M. ulcerans Agy99 | MUL_2440 | - | 0.0 | 99.53% (637) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_4726 | - | 5e-34 | 34.03% (288) | hypothetical protein Mvan_4726 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1497|M.marinum_M --MNFAVLSPEANSARILSGPGPGPLLAAAAAWDGIGQELAAAASAFSSL MUL_2440|M.ulcerans_Agy99 -------------------------MLAAAAAWDGTGQELAAAASAFSSL Mb1828|M.bovis_AF2122/97 MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSV Rv1800|M.tuberculosis_H37Rv MLPNFAVLPPEVNSARVFAGAGSAPMLAAAAAWDDLASELHCAAMSFGSV Mflv_1918|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5455|M.smegmatis_MC2_155 -------------------------------------------------- TH_3724|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MAB_0809c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_4726|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_1497|M.marinum_M TSDLAGAAWQGPSAAAMASVATSYVRWLGSAASGAVQTARQAATSAAVFE MUL_2440|M.ulcerans_Agy99 TSDLAGAAWQGPSAAAMASVATSYVRWLGSAASGAVQTARQVATSAAVFE Mb1828|M.bovis_AF2122/97 TSGLVVGWWQGSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFE Rv1800|M.tuberculosis_H37Rv TSGLVVGWWQGSASAAMVDAAASYIGWLSTSAAHAEGAAGLARAAVSVFE Mflv_1918|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_5455|M.smegmatis_MC2_155 -------------------------------------------------- TH_3724|M.thermoresistible__bu -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MAV_4704|M.avium_104 -------------------------------------------------- MAB_0809c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_4726|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_1497|M.marinum_M AARTATVPLELVAANRSALMSMVAANVFGLNAPAIAAIEAQYEQMWAQNV MUL_2440|M.ulcerans_Agy99 AARTATVPLELVAANRSALMSMVAANVFGLNAPAIAAIEAQYEQMWAQNV Mb1828|M.bovis_AF2122/97 EALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYEWMWAQDA Rv1800|M.tuberculosis_H37Rv EALAATVHPAMVAANRAQVASLVASNLFGQNAPAIAALESLYECMWAQDA Mflv_1918|M.gilvum_PYR-GCK --------------MGKGDFGLKASEFTGRSSTRFADSVRRRPGGATYGL MSMEG_5455|M.smegmatis_MC2_155 --------------MGRLLHSLSTAFLVFVAVVVLCVSTS---------- TH_3724|M.thermoresistible__bu ------------------VVAVGALTWGGXGVASPAGQPE---------- MLBr_01182|M.leprae_Br4923 ---------------------MFD--FAALSPETNSTRMYL--------- MAV_4704|M.avium_104 ---------------------MTNPHFAWLPPEVNSALIYS--------- MAB_0809c|M.abscessus_ATCC_199 --------------------MLAAPVWMASPPEVHSALLSS--------- Mvan_4726|M.vanbaalenii_PYR-1 -----------------MRRRLRSAAWGLLSLVIAVLFAWG--------- : MMAR_1497|M.marinum_M GAMFGYHVGVSEALSGLAPWQEVLSGVSGRVASALEGTSAAAAAALGPTA MUL_2440|M.ulcerans_Agy99 GAMFGYHVGVSEALSGLAPWQEVLSGVSGRVASALEGTSAAAAAALGPTA Mb1828|M.bovis_AF2122/97 AAMAGYYVGASAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRA Rv1800|M.tuberculosis_H37Rv AAMAGYYVGASAVATQLASWLQRLQSIPGAASLDARLPSSAEAPMGVVRA Mflv_1918|M.gilvum_PYR-GCK YRHDGLGVGTWAWVFARSSRSFPRSRRCWRYPRGVPTPVAVLVANTTALV MSMEG_5455|M.smegmatis_MC2_155 ----------------------------------MPTAAHLLLNHPHALV TH_3724|M.thermoresistible__bu -----------------------------------RAAALRLTATADAII MLBr_01182|M.leprae_Br4923 ----------------------------------GPGSSPILTAAAAWVV MAV_4704|M.avium_104 ----------------------------------GPGPGPLLAAAAAWDG MAB_0809c|M.abscessus_ATCC_199 ----------------------------------GPGPGPLLAAAAEWSS Mvan_4726|M.vanbaalenii_PYR-1 -----------------------------------SVVTSTSAGAGTALV MMAR_1497|M.marinum_M LTAAGSALPAAATDVTLVIGGSGFPIPSQSYVDNVVNNFVTPNFPSFTVS MUL_2440|M.ulcerans_Agy99 LTAAGSALPAAATDVTLVIGGSGFPIPSQSYVDNVVNNFVTPNFPSFTVS Mb1828|M.bovis_AF2122/97 VNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYMSGSVPGVIAQ Rv1800|M.tuberculosis_H37Rv VNSAIAANAAAAQTVGLVMGGSGTPIPSARYVELANALYMSGSVPGVIAQ Mflv_1918|M.gilvum_PYR-GCK MGGTFHPLTGPRDSPEFVTAYLDNAVDNQISAAYGYAVTNA--------- MSMEG_5455|M.smegmatis_MC2_155 IGGTGTPVP----PPEYVNGQTDNYIGAEFPGEYRYAVH----------- TH_3724|M.thermoresistible__bu MPGTKIGYIP---SQDEFTAYATAVIGATAGAPGAVDYLG---------- MLBr_01182|M.leprae_Br4923 LAKELTAAAQGLQSAVEALLT-TFEGESAAALAERVTPY----------- MAV_4704|M.avium_104 LAEELASSAQSFSSVTSDLASGSWQGASSAAMMTVANQY----------- MAB_0809c|M.abscessus_ATCC_199 LGAHYSATAQELRAILAATHASAWHGPSAETYVAAHTPY----------- Mvan_4726|M.vanbaalenii_PYR-1 MGGNGHPLSVPQDTPDYINKYVTAADDAFIAPSGLCGPQCS--------- : MMAR_1497|M.marinum_M NAISLFTPAESYWITGIKTMTEDASWAEGLTILDTAIKAQLAAG------ MUL_2440|M.ulcerans_Agy99 NAISLFTPAESYWITGIKTMTEDASWAEGLTILDTAIKAQLAAG------ Mb1828|M.bovis_AF2122/97 ---ALVTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAG------ Rv1800|M.tuberculosis_H37Rv ---ALFTPQGLYPVVVIKNLTFDSSVAQGAVILESAIRQQIAAG------ Mflv_1918|M.gilvum_PYR-GCK --VAVYTPEEFFPLGG---LTFDDSVAEGLANLGRCLRAEPGCVFNADPA MSMEG_5455|M.smegmatis_MC2_155 ------TPQNFWPVYGS--MSFDESTVAGLAALQAEMAKEG--------- TH_3724|M.thermoresistible__bu ------VPGEFWPATGLDSLTFDASVAXGQAMLTPMVDGAIES------- MLBr_01182|M.leprae_Br4923 --------EKWLTQNAASAELTATQLTVAANAYETAFTMTVPPL------ MAV_4704|M.avium_104 --------VSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPA------ MAB_0809c|M.abscessus_ATCC_199 --------LEWLNQGALESNARAVQHGAAAGAYSTALAVMPTLA------ Mvan_4726|M.vanbaalenii_PYR-1 -LVATYTPAQIRFVNGIFDMTYDESVAVGQANLNDCIQGSDCTATLAPYS . . MMAR_1497|M.marinum_M -------------NNVVVQGYSQGAGIASLEMSNLKAAGV-PTG--SVSF MUL_2440|M.ulcerans_Agy99 -------------NNVVVQGYSQGAGIASLEMSNLKAAGV-PTG--SVSF Mb1828|M.bovis_AF2122/97 -------------NNVTVFGYSQSATISSLVMANLAASAD-PPSPDELSF Rv1800|M.tuberculosis_H37Rv -------------NNVTVFGYSQSATISSLVMANLAASAD-PPSPDELSF Mflv_1918|M.gilvum_PYR-GCK VAARVGTVAPRHDDTFVVFGYSQSAAVASLLKRQLIDAP--GPEPAATTF MSMEG_5455|M.smegmatis_MC2_155 ----------HFGSPLVILGYSSSTRILTADKNRRIAD---GDYAVDINY TH_3724|M.thermoresistible__bu ------------DTPIVVFGHSQSAVIATKEKQRLLAEYPDPDTAPDVTF MLBr_01182|M.leprae_Br4923 ---------------MVFVNRAQACLLIMSNIFGQNSTAIAEKEAEYTEM MAV_4704|M.avium_104 ---------------VVAANRALVQALAATNWLGQNTPAIADIEAAYEQM MAB_0809c|M.abscessus_ATCC_199 ---------------ELAANHATHAALVATNFFGINTIPILATEADYVRM Mvan_4726|M.vanbaalenii_PYR-1 ETG----PHTVADSTYVIYAYSQSATVAANQKLQLIAHP----VASTVSF : : MMAR_1497|M.marinum_M SLIGNAMNPNGGLYERFAGLVSPSLGKTFWGATP-----DNYYTTDVYTL MUL_2440|M.ulcerans_Agy99 SLIGNAMNPNGGLYERFAGLVSPSLGKTFWGATP-----DNYYTTDVYTL Mb1828|M.bovis_AF2122/97 TLIGNPNNPNGGVATRFPGISFPSLGVTATGATP-----HNLYPTKIYTI Rv1800|M.tuberculosis_H37Rv TLIGNPNNPNGGVATRFPGISFPSLGVTATGATP-----HNLYPTKIYTI Mflv_1918|M.gilvum_PYR-GCK MLAANPMRPNGGVLGRFPALTIPILGITFHGATPTAG-VDGAYRTVDVVR MSMEG_5455|M.smegmatis_MC2_155 VLVSDVAKGNGGVMARFPGWHIPILGVTFDGATRTDS-DGYAFDTKSISF TH_3724|M.thermoresistible__bu VMVANPNRPNGGLLARFPGLYIPILGVTFNGATPAPA-DG-PFDSYDVAR MLBr_01182|M.leprae_Br4923 WIQDAAAMTSYQASVLEAVGATKAFTAPPLGVNEVGL-AQEVVEEVVEEV MAV_4704|M.avium_104 WASDVAAMFGYHA------------------------------------- MAB_0809c|M.abscessus_ATCC_199 WVQAATTMATYQTASEVALASAPPSTPPPSILHDHDH-GHDDHDHEHGHD Mvan_4726|M.vanbaalenii_PYR-1 LLVANPNRPDGGILERFVGAYIPLLGITFNGSTPTFSPQPRPLTTVDVAR MMAR_1497|M.marinum_M EYDGFA-DFPRYPLNFVSDLNAIMGIYYVHTQYPTLTA--AQVATAFTLP MUL_2440|M.ulcerans_Agy99 EYDGFA-DFPRYPPNFVSDLNAIMGIYYVHTQYPTLTA--AQVATAFTLP Mb1828|M.bovis_AF2122/97 EYDGVA-DFPRYPLNFVSTLNAIAGTYYVHSNYFILTP--EQIDAAVPLT Rv1800|M.tuberculosis_H37Rv EYDGVA-DFPRYPLNFVSTLNAIAGTYYVHSNYFILTP--EQIDAAVPLT Mflv_1918|M.gilvum_PYR-GCK QYDGLGGDFPVRPLNLLATVNALLGYGIMHGETVDVPF--------AQAR MSMEG_5455|M.smegmatis_MC2_155 VHDGWS-DFPVYPLNVLALANAVAGIAVLHPTYPELDR--------PDLV TH_3724|M.thermoresistible__bu EFDGWA-DFPRYPLNLVATANAILGIYYLHGGYYELLTENPDILDDPERT MLBr_01182|M.leprae_Br4923 VEE-------------------------VVEAEQAISQAALDQAVNEGME MAV_4704|M.avium_104 -------------------------------------------------- MAB_0809c|M.abscessus_ATCC_199 DDHGHGDLDPTDPEWWVHVAGEMVEHFELLLNNLLTDPAALLTNLPMVLA Mvan_4726|M.vanbaalenii_PYR-1 QYDGWA-DFPTNPLNLLADLNAIMGTILLHPNYSDAGT----------PQ MMAR_1497|M.marinum_M -TEGATMTTYHMIPTENLPLLEPLRGVPFIGNTLADLVQPDLKVLVNLGY MUL_2440|M.ulcerans_Agy99 -TEGATMTTYHMIPTENLPLLEPLRGVPFIGNTLADLVQPDLKVLVNLGY Mb1828|M.bovis_AF2122/97 NTVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGY Rv1800|M.tuberculosis_H37Rv NTVGPTMTQYYIIRTENLPLLEPLRSVPIVGNPLANLVQPNLKVIVNLGY Mflv_1918|M.gilvum_PYR-GCK FQGREGDTDYYLIGTDLLPLLQPLLLF-VPRPILSALDAP-LRVLVEDAY MSMEG_5455|M.smegmatis_MC2_155 PVGSTGDTEYFVIGTDIMPLLMPLETIGVPRPILLAVDEP-LRVLVEAGY TH_3724|M.thermoresistible__bu IVQQYGDTTYYLIRTEQLPLLRPLRDLGVPEEFVDALEPY-VRRIVDLGY MLBr_01182|M.leprae_Br4923 ATVVPQVDQQVNVDVATPQTAVPDSSSAAAPQLWGGFAQHLSPINDTLSM MAV_4704|M.avium_104 -----------------------DASAAVA---------KLPPWNEVLQN MAB_0809c|M.abscessus_ATCC_199 DVAFHAAQLASTIGQFAPALIQPALALAIANLGWAAGFAGLAGIQPSPEI Mvan_4726|M.vanbaalenii_PYR-1 LQGQYQDSTYYLIPAPITPVLVPLTWVPIVGKPLAIALDPAVRVLVEMGY MMAR_1497|M.marinum_M GDPNYGYSTGPANVPTPFGLFPDVAPATVFDALVAGTQQGISDAAADIG- MUL_2440|M.ulcerans_Agy99 GDPNYGYSTGPANVPTPFGLFPDVAPATVFDALVAGTQQGISDAAADIG- Mb1828|M.bovis_AF2122/97 GDPAYGYSTSPPNVATPFGLFPEVSPVVIADALAAGTQQGIGDFAYDVS- Rv1800|M.tuberculosis_H37Rv GDPAYGYSTSPPNVATPFGLFPEVSPVVIADALVAGTQQGIGDFAYDVS- Mflv_1918|M.gilvum_PYR-GCK DR------DAGPGDPTTARWWPVKDFAGTAAKLIASVPVAVDNLTEGFG- MSMEG_5455|M.smegmatis_MC2_155 RR------DIAPGAPTPARLIPIVNPITLTRNFIAAIPVGVDDAMEELG- TH_3724|M.thermoresistible__bu DR------NTPYGEPAPVRVLPPLTPAPG--------PATQHNAGQGIT- MLBr_01182|M.leprae_Br4923 INNHAGMANAGLSLVNGMGSAMKSLAPTTTKAAESAFKAMGSAVQSTGR- MAV_4704|M.avium_104 LG------------------------------------------------ MAB_0809c|M.abscessus_ATCC_199 LAVEPGSVEDAPMAASAGTALAPSPPASAAAPAAPASAPAPTASGTAPA- Mvan_4726|M.vanbaalenii_PYR-1 DR------TVNPGQPTPARYLYVPNLIKAALNFAMAIPTGWDDAISYLTG MMAR_1497|M.marinum_M ---AWQLPSLPDISLSGISN-----------ALGSDPWSALSNATLPTLS MUL_2440|M.ulcerans_Agy99 ---AWQLPSLPDISLSGISN-----------ALGSDPWSALSNATLPTLS Mb1828|M.bovis_AF2122/97 ---HLELP-LPADGSTMPST-----------APGS-------GTPVPPLS Rv1800|M.tuberculosis_H37Rv ---HLELP-LPADGSTMPST-----------APGS-------GTPVPPLS Mflv_1918|M.gilvum_PYR-GCK ---LGRVLGTPVPGVFGVGG-----------------PDLPDVDEGGAVT MSMEG_5455|M.smegmatis_MC2_155 ---HGRPLGTQPSGVFGVGGEDTELKGLPAGVISLAKPTLPVSSHTTVVE TH_3724|M.thermoresistible__bu ---VASATSTP-------------------------------DKRTPVVE MLBr_01182|M.leprae_Br4923 ---GLLGSSSGGHVTAQLGR--------------------AASIGSLRVP MAV_4704|M.avium_104 -------------------------------------------------- MAB_0809c|M.abscessus_ATCC_199 ---PPSPPPVGDPGFSFPYA--------------------VGGGPRLGTG Mvan_4726|M.vanbaalenii_PYR-1 DPDCRPFHTTVPASPFGVGGPPVYTGAIDPYGEPTPYLAPPVETHGEAAP MMAR_1497|M.marinum_M VSTIENAIKGVQTATTDIANTISFDATTAYATLLPTADVVNAMVTTLPAY MUL_2440|M.ulcerans_Agy99 VSTIENAIKGVQTATTDIANTISFDATTAYATLLPTADVVNAMVTTLPAY Mb1828|M.bovis_AF2122/97 ---IDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSY Rv1800|M.tuberculosis_H37Rv ---IDSLIDDLQVANRNLANTISKVAATSYATVLPTADIANAALTIVPSY Mflv_1918|M.gilvum_PYR-GCK SDIDEDAVAQRDSASSTERSAPAEESRSAVGGADSDGRDDVVDPEPAAPE MSMEG_5455|M.smegmatis_MC2_155 KTERKDLAKPAAEPEPVVEDEPAVEDETPVADTKKASPKPLRPKVRGPIS TH_3724|M.thermoresistible__bu APVEE---PPVQTGRSTLKREKPVSARHLVRNSLRAVPGLRRGEPAATPT MLBr_01182|M.leprae_Br4923 QTWTTASQPVTAATRALSPARVAVATESESAPLLGGGLPMAPM------- MAV_4704|M.avium_104 --FSNASTAVTRP------------------------------------- MAB_0809c|M.abscessus_ATCC_199 LALAAQVRRGTSAAARSSAREQAAAAETAAARQARRRRDKGKQQGRGIEY Mvan_4726|M.vanbaalenii_PYR-1 GSGSPAAHPAGTEPPETVTFSPTTESTPSTLLPETPAESEDMPPDFVEND MMAR_1497|M.marinum_M NLKLFLDGILQVLDGDPAGLIYALGAPIAADTALVTLLAGFNLYAYLYAF MUL_2440|M.ulcerans_Agy99 NLKLFLDGILQVLDGDPAGLIYALGAPIAADTALVTLLAGFNLYAYLYAF Mb1828|M.bovis_AF2122/97 NIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAG Rv1800|M.tuberculosis_H37Rv NIHLFLEGIQQALKGDPMGLVNAVGYPLAADVALFTAAGGLQLLIIISAG Mflv_1918|M.gilvum_PYR-GCK AETSEAETVTETEADD---------ADDADDGADADDEDIDADGADADGE MSMEG_5455|M.smegmatis_MC2_155 FDAPKLPTIRKATGDRPLKRLLSALTPKRPKPASSHDAGPAAGNKDTDNA TH_3724|M.thermoresistible__bu PDVTPDVTPDAPAGQP--------------EPAEPNESAAPPAAAEADDA MLBr_01182|M.leprae_Br4923 ---------------------------VPGGGSGTGGVNTALRLQPRA-- MAV_4704|M.avium_104 --------------------------------AGSGAVARGYTSRIAG-- MAB_0809c|M.abscessus_ATCC_199 MDMNATARCEEPAPDTTASHRGAGTMGFAGTVIKTGATASGLAMLSRDDD Mvan_4726|M.vanbaalenii_PYR-1 TPDSDEVSPTEDDALKDTETINESQDGPTESASGVSGEDAADADSRSADA MMAR_1497|M.marinum_M NKILPGVL-------------- MUL_2440|M.ulcerans_Agy99 NKILPGVL-------------- Mb1828|M.bovis_AF2122/97 RTIANDISAIVP---------- Rv1800|M.tuberculosis_H37Rv RTIANDISAIVP---------- Mflv_1918|M.gilvum_PYR-GCK DTAGNTAEAA------------ MSMEG_5455|M.smegmatis_MC2_155 DKPAARADDAA----------- TH_3724|M.thermoresistible__bu SE-------------------- MLBr_01182|M.leprae_Br4923 -FVMPRNPAAG----------- MAV_4704|M.avium_104 -FLAPRAPQ------------- MAB_0809c|M.abscessus_ATCC_199 LFEGVRAPMVPNTWDPEHGRQD Mvan_4726|M.vanbaalenii_PYR-1 DSLSADAGDSAPADAAAADTAA