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MSRPTAKDRTAAEAVMCAIQTNPATDAVRFLPRGEGPGTVISYEGLHARAARLAAALQARGAQGERVILA SRDNIEMTVGLVACLYSGAVAVPVPVPNMNKSGPALLRLQAIARDAQARVFLTDLPSVDSQSNVRTLPEG LSGLIWLNTDDASADRADWQPPRYAPESAALLQYTSGSTGQPKGVMLTQANLLSNAHQIERRWEQDQNEL LVSWLPQYHDFGLIFMALQALYLGATVVSMPPSAFVQDPLRWLRCLTQYRGTNSGAPNFAFDLCVEQSTP AQREGLDLRSVKALNCGAEPVRAETMRRFLAAFAPFGLRPDALRPGYGLAEATLFVTGWRGPTVKTLTLD QRQLNEGRVVECDIAATPLTEVVCCGPAGPEVELAIVSTQTQQPCAADEVGEIWVRGPNISRGYFNGAGA SQDCFGNVAGQGQYLRTGDLGFVQDGDLYVTGRLKDLVIVRGVNHYPQDIEFSVEQSHPAIRPGYCAAFT LEVDGEERLGVAAEIAADDPAQDTLESAMDSILQAITSHHEVVPYRLVLLARGAIPKTSSGKIQRQLCKQ LLLTDQLPILGDRVSTATISSTPQQPDGGARSPKYRAMEQYLLELLNLSPEELESGNNLAAYGFDSIDGA ALAKKIKADWGIEVPMEILPLLTIRDLVDTLAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1170 | fadD29_1 | - | 100% (663) | fatty-acid-CoA ligase FadD29_1 |
| M. marinum M | MMAR_0468 | - | 5e-94 | 39.31% (547) | fatty-acid-CoA ligase |
| M. marinum M | MMAR_1876 | - | 7e-85 | 34.06% (646) | long-chain acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2974c | fadD29 | 3e-78 | 32.57% (571) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_0402 | - | 1e-79 | 34.29% (557) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv2950c | fadD29 | 2e-78 | 32.57% (571) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_00100 | fadD32 | 1e-77 | 34.92% (590) | long-chain-fatty-acid--CoA ligase |
| M. abscessus ATCC 19977 | MAB_3579c | - | 5e-88 | 37.55% (546) | putative acyl-CoA synthase/polyketide synthase |
| M. avium 104 | MAV_4122 | - | 1e-87 | 36.28% (645) | AMP-binding enzyme |
| M. smegmatis MC2 155 | MSMEG_4731 | - | 5e-82 | 36.84% (551) | acyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_4458 | - | 1e-113 | 39.21% (635) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
| M. ulcerans Agy99 | MUL_1117 | - | 5e-92 | 38.76% (547) | fatty-acid-CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_0999 | - | 9e-95 | 35.40% (613) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4458|M.thermoresistible__bu -------------------------LLS-LLRQRSERYGDKIAFDYCTG-
Mvan_0999|M.vanbaalenii_PYR-1 --------------------MFLEDLLSRRLRRHADEFPDERILSFLDD-
MAB_3579c|M.abscessus_ATCC_199 ----------------MQTTYDFTDYFS-TVTEWVARQPDQIALGYLEEG
Mb2974c|M.bovis_AF2122/97 ---------------------MSESSLADLLQKAASQYPNRAAYKFIDYD
Rv2950c|M.tuberculosis_H37Rv ---------------------MSESSLADLLQKAASQYPNRAAYKFIDYD
Mflv_0402|M.gilvum_PYR-GCK -----------------------------MLHGRASMRPDDVAFTFTEYA
MSMEG_4731|M.smegmatis_MC2_155 ---------------------MTRSSVIGVLRERASLQPGDVAFTFIDYD
MLBr_00100|M.leprae_Br4923 MTGEGRMAYHNPFIVNGKIRFPPNTNLVRHVEKWAKVRGDKLAYRFLDFS
MMAR_1170|M.marinum_M -------------------MSRPTAKDRTAAEAVMCAIQTNPATDAVRFL
MUL_1117|M.ulcerans_Agy99 ----------------MAHLPPPHLNLVERLAWRARNQPDELAMVELRG-
MAV_4122|M.avium_104 -----------------------METLIDYLHLWEERRPEQTLFRFVDVD
TH_4458|M.thermoresistible__bu --EQEHSR-LTYQELDIRARAIAAHLQDQG--VAGERVLVLCPSGLDFIT
Mvan_0999|M.vanbaalenii_PYR-1 --RLEVADSLTFGRLDDRARSVAAGLLDRG--MGGAPVVLSYPPGLDFVS
MAB_3579c|M.abscessus_ATCC_199 A-GELTERAWTYAELVSHATAVAARLREDL--EPGDRTLLLYPPGLPFVA
Mb2974c|M.bovis_AF2122/97 TDPAGFTETVTWWQVHRRAMIVAEELWIYA--SSGDRVAILAPQGLEYII
Rv2950c|M.tuberculosis_H37Rv TDPAGFTETVTWWQVHRRAMIVAEELWIYA--SSGDRVAILAPQGLEYII
Mflv_0402|M.gilvum_PYR-GCK DDPAGVAETVTWSQLSRRTANVARVLARHG--SAGDRAVILAPQGLEYIL
MSMEG_4731|M.smegmatis_MC2_155 TDPEGVAHTLTWSQLNRRVQSLAYEMQARS--AVGDRAVILAPQGLDYVV
MLBr_00100|M.leprae_Br4923 TGRDGVARDILWSEFSARNRAVGARLQQVT--QPGDRIAILCPQNLDYLI
MMAR_1170|M.marinum_M PRGEGPGTVISYEGLHARAARLAAALQARG--AQGERVILASRDNIEMTV
MUL_1117|M.ulcerans_Agy99 --MCGETDKATYARLDARARAIAFQLKSLG--NQGDRVLLVMGHCLDYVV
MAV_4122|M.avium_104 ---GRELEHYTYRSFAERTRELAAYLSTEAGLRAGDRALLVYPPGLEMVA
: . : :. : * : :
TH_4458|M.thermoresistible__bu AMFGCFYVGAVAVPVHPPVHN---RLLSRVASIVADVRATSVLTTAATRA
Mvan_0999|M.vanbaalenii_PYR-1 AFCGCLYAGAIAVPAALPQSR---RTAERLAAVLKDSAARCVLTSAAHRA
MAB_3579c|M.abscessus_ATCC_199 AFLGCLAAGVVAVPAPLPDGRD--KAQHRLAGIIADAGTRVVLTESSVAP
Mb2974c|M.bovis_AF2122/97 AFMGVLQAGLIAVPLPVPQFG---IHDERISSALRDSAPSIILTTSSVID
Rv2950c|M.tuberculosis_H37Rv AFMGVLQAGLIAVPLPVPQFG---IHDERISSALRDSAPSIILTTSSVID
Mflv_0402|M.gilvum_PYR-GCK AFLGSMQAGMIAVPLPLPHRG---SNHDRVSAVFTDTTPAVVLTTSAVAG
MSMEG_4731|M.smegmatis_MC2_155 AFLASLQAGRIGVPLSVPFPG---VHDDRVTAVLRDTAPSIVLTTSAVSS
MLBr_00100|M.leprae_Br4923 SFFGALYSGRIAVPLFDPAEP---GHVGRLHAVLDDCTPSTILTTTDSAE
MMAR_1170|M.marinum_M GLVACLYSGAVAVPVPVPNMNKSGPALLRLQAIARDAQARVFLTDLPSVD
MUL_1117|M.ulcerans_Agy99 GFLACAYARRVAVNLPVPRRA---KHLDRLAHVVADCGAEVLLTSGPEAK
MAV_4122|M.avium_104 ALYACARIGVIAVPVSPPLPMSFESGLAKLGFIARDCQARAVLSTKQFEY
.: . :.* * :: * . .*:
TH_4458|M.thermoresistible__bu DLKEILDG---LHDGDPLRWLAVDTIEADDE---TSWTPTTVDTDSVAFV
Mvan_0999|M.vanbaalenii_PYR-1 ELYSHAG-----AAPSVVDVIATDVLPSRPG---DGRVALP-DPDQVAFL
MAB_3579c|M.abscessus_ATCC_199 LIAGWAD-----ALPTPIALIATDAIPVELG---REFVPVRSAPSDTAFL
Mb2974c|M.bovis_AF2122/97 EVTTYAPHACAAQGQSAPIVVAVDALDLSSS---RALDPTRFERPSTAYL
Rv2950c|M.tuberculosis_H37Rv EVTTYAPHACAAQGQSAPIVVAVDALDLSSS---RALDPTRFERPSTAYL
Mflv_0402|M.gilvum_PYR-GCK DVGAYVD---EARMQIAPTIVTVDTLDLDGTPSDDEPAVAAGEAPDIAYL
MSMEG_4731|M.smegmatis_MC2_155 HIAEYLE---PQAGQAAPWIAEIDTLDLDTR----RRPVKREQAPETAYL
MLBr_00100|M.leprae_Br4923 GVRKFIR---GRFAKERTRVIAVDAVPNEVA---ATWQQPEANEETVAYL
MMAR_1170|M.marinum_M SQSNVRTLP---EGLSGLIWLNTDDASADRA----DWQPPRYAPESAALL
MUL_1117|M.ulcerans_Agy99 ELTASVAAD---LRLDFLTVLRLDWLLAIPD---EDWQPVAPASKDVCLL
MAV_4122|M.avium_104 DFRMLLGQRHGGQPWSDAGLPELPWFATDGAQ-EFGGAPVPDTPGDVLFL
:
TH_4458|M.thermoresistible__bu QYTSGSTSTPKGVVLTHHNLLANL---ESISRDAGQ---------GDEAR
Mvan_0999|M.vanbaalenii_PYR-1 QYTSGSTRSPRGVMVRHGDLAANL---NSLREILAF---------DDHAT
MAB_3579c|M.abscessus_ATCC_199 QYTSGSTNAPKGVIVTHGNLVHNE---QELGARIEN---------DPSFS
Mb2974c|M.bovis_AF2122/97 QYTSGSTRAPAGVVLSHKNVITNC---VQL---MSDYIG---DSEKVPST
Rv2950c|M.tuberculosis_H37Rv QYTSGSTRAPAGVVLSHKNVITNC---VQL---MSDYIG---DSEKVPST
Mflv_0402|M.gilvum_PYR-GCK QYSSGSTRLPTGVMISHRNLQSNY---EQL---MRSFFAVPHIRSTAELT
MSMEG_4731|M.smegmatis_MC2_155 QYTSGSTRTPAGVMVSHRNLTANF---EQV---VAGFF--PDNIAPSDTT
MLBr_00100|M.leprae_Br4923 QYTSGSTRIPSGVQITHLNLPTNV---LQV---LNSLQG------QEGDR
MMAR_1170|M.marinum_M QYTSGSTGQPKGVMLTQANLLSNA---HQIERRWEQ---------DQNEL
MUL_1117|M.ulcerans_Agy99 QYTSDSTSAPRGVVVTHDNLMFNC---AQIQYGFGL---------TAEDR
MAV_4122|M.avium_104 QYTSGSTSDPKGVIVSHKNVIANVSAFT-----------------GGSEV
**:*.** * ** : : :: *
TH_4458|M.thermoresistible__bu VVSWLPLHHDMGLIGGIFGVVHFGGTAYLMPPSSFIQRPMSWLEAISWHG
Mvan_0999|M.vanbaalenii_PYR-1 GVSWLPVFHDMGLIAGVLLPIWSARPQFLMAPATFVRNPLSWLEAISRYG
MAB_3579c|M.abscessus_ATCC_199 MLSWLPQFHDMGLIGMLLWPLFYGGTSRFLSPVTFIKHPIQWIRAMSKYR
Mb2974c|M.bovis_AF2122/97 PVSWLPFYHDMGLMLGIILPMINQDTAVLMSPMAFLQRPARWMQLLAKHR
Rv2950c|M.tuberculosis_H37Rv PVSWLPFYHDMGLMLGIILPMINQDTAVLMSPMAFLQRPARWMQLLAKHR
Mflv_0402|M.gilvum_PYR-GCK IVSWLPFYHDMGLVLGVCAPILGGHPAKLTSPVAFLEKPSRWVRALAENP
MSMEG_4731|M.smegmatis_MC2_155 SISWLPLYHDMGLMLGLCAPVLGGWHTVLISPFAFLAKPARWMQLLATHP
MLBr_00100|M.leprae_Br4923 GVSWLPFFHDMGLIT-VLLPSVLGHSFTFMTPAAFVRRPGRWIRELARKP
MMAR_1170|M.marinum_M LVSWLPQYHDFGLIFMALQALYLGATVVSMPPSAFVQDPLRWLRCLTQYR
MUL_1117|M.ulcerans_Agy99 ALSWLPLYHDMGLILGVLTPIFAGFPVVLADPLSFVKRPDLWLRAISDYR
MAV_4122|M.avium_104 LVSWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPSAWLRLISDVR
:**** .**:**: * *: * *:. ::
TH_4458|M.thermoresistible__bu A----NISVGPNFGYQLCVER--STPEERATLDLSTWVRAYCGAEPVRAA
Mvan_0999|M.vanbaalenii_PYR-1 G----THQGAPNFGYQACVDA--ARAAGATTFDLRNWRVAWNGAEPVRPD
MAB_3579c|M.abscessus_ATCC_199 A----TVGVAPNFAFDLVARR--CTHEALEGVDLSCVRSLLNGSEPVQWA
Mb2974c|M.bovis_AF2122/97 A----QISSAPNFGFELAVRR--TSDDDMAGLDLGHVRTIVTGAERVNVA
Rv2950c|M.tuberculosis_H37Rv A----QISSAPNFGFELAVRR--TSDDDMAGLDLGHVRTIVTGAERVNVA
Mflv_0402|M.gilvum_PYR-GCK Q----AFSAAPNFAFELAARK--TRDSDLAGLDLGGVLGIINGAERVNPA
MSMEG_4731|M.smegmatis_MC2_155 A----TVTAAPNFAFDLAARK--TSDADLTGMDLGDVRCVLSGSERVHEP
MLBr_00100|M.leprae_Br4923 EDTGGTFSAAPNFAFEHAAMRGLPRDDELP-LDLSNVKGILNGSEPVSPA
MMAR_1170|M.marinum_M G----TNSGAPNFAFDLCVEQ--STPAQREGLDLRSVKALNCGAEPVRAE
MUL_1117|M.ulcerans_Agy99 I----TFTGGPNFAYDLCADA--ASYTDLSGIDLSCWNVALNGAEPIRAT
MAV_4122|M.avium_104 A----THTPVPNFALEYCLREDKVPAAELAGIDLSSLECIVVGAEPLRAN
***. : .** *:* :
TH_4458|M.thermoresistible__bu TMRRFTEAFAPAGFRADAFHPVYGLAEATLFVSGRPENVLPTVRSLDNAA
Mvan_0999|M.vanbaalenii_PYR-1 TLHQFRDQFALNGFGSECLSPGYGLAEATLVVSGSDGSKPATELTVDESE
MAB_3579c|M.abscessus_ATCC_199 SIERFTTLLAPFGLAEHAVTPVYGLAEATLFVTGDPHGTPVTTAVVDGEA
Mb2974c|M.bovis_AF2122/97 TLRRFTERFAPFNLSETAIRPSYGLAEATVYVATAGPGRAPKSVCFDYQQ
Rv2950c|M.tuberculosis_H37Rv TLRRFTERFAPFNLSETAIRPSYGLAEATVYVATAGPGRAPKSVCFDYQQ
Mflv_0402|M.gilvum_PYR-GCK TLERFADRFAHFNFRDNMLRPSYGLAEATVFVASGIYRESADEARFDSNE
MSMEG_4731|M.smegmatis_MC2_155 TLRRFSDRFAAFNLHEQALRPSYGLAEATLFVATRETGHPPKVARFAAQE
MLBr_00100|M.leprae_Br4923 SMRKFFEAFAPYGLKQTAVKPSYGLAEATLFVSTTPMDESPTVIHVDRYE
MMAR_1170|M.marinum_M TMRRFLAAFAPFGLRPDALRPGYGLAEATLFVTG-WRGPTVKTLTLDQRQ
MUL_1117|M.ulcerans_Agy99 TLERFNAALAPLGWAPTCMQPSYGLAENTLAVSTKIPATEPTVVEIYVAA
MAV_4122|M.avium_104 TFHQFRERFAPYGLRPEALTGAYGMAESTLIVSIRGRQT--LTVNKRGLE
::.:* :* . . **:** *: *:
TH_4458|M.thermoresistible__bu LREHRVVPAAADDANAAAVVGCGPAAYGEEIVIVDPATRREFPPDVVGEI
Mvan_0999|M.vanbaalenii_PYR-1 LHVGQVRPRIDDGPGVKRLVGSGRPAAGTEVQIVR-ADGRVAEPHTLGEI
MAB_3579c|M.abscessus_ATCC_199 LAENRLVVANEGAPRSRVLVASGR-IGGIEVSVVG-ADGAPLPDGEIGEI
Mb2974c|M.bovis_AF2122/97 LSVGQAKRTENG-SEGANLVSYGAP-RASTVRIVDPETRMENPAGTVGEI
Rv2950c|M.tuberculosis_H37Rv LSVGQAKRAENG-SEGANLVSYGAP-RASTVRIVDPETRMENPAGTVGEI
Mflv_0402|M.gilvum_PYR-GCK LSAGR-VARRT--TGGTALVNYTLP-QAPTVRIVDVETNRECASDVVGEI
MSMEG_4731|M.smegmatis_MC2_155 LSDGRAVPCDD--ENGTALVSYGMP-ESPTVRIVDPQTRAECPTGIVGEI
MLBr_00100|M.leprae_Br4923 LNNQRFVEVPADAPNAVAQVSAGKVGVSEWAIIVDADTASELPDGQIGEI
MMAR_1170|M.marinum_M LNEGRVVECDIAATPLTEVVCCGPAGPEVELAIVSTQTQQPCAADEVGEI
MUL_1117|M.ulcerans_Agy99 LRQSQVCAPRGD-SPSRRLVSSGRILAGTMVKIVDPETGHPVGPDRVGEI
MAV_4122|M.avium_104 KNVARVEKALPENSNQVPLVSCGKPLEETVVRVVDPQTRQALGEGRVGEV
: * :* :**:
TH_4458|M.thermoresistible__bu WVAGENVAQGYLGKPSESAETFAAHLAD----------SGRGPFLRTGDY
Mvan_0999|M.vanbaalenii_PYR-1 WVRSDSVAQGYWNNPGETSGTFGACLT-----------TGEGPYLRTGDL
MAB_3579c|M.abscessus_ATCC_199 WLRGTSVAAGYWNLPELSAEIFGATPI-----------GGTGGWLRTGDL
Mb2974c|M.bovis_AF2122/97 WVQGDNVGLGYWRNPQQTEATFRARLVT------PSPGTSEGPWLRTGDL
Rv2950c|M.tuberculosis_H37Rv WVQGDNVGLGYWRNPQQTEATFRARLVT------PSPGTSEGPWLRTGDL
Mflv_0402|M.gilvum_PYR-GCK WVHGENVAAGYWSRPADEQQCFGATLAD------PSPGTPAGPWLRTGDL
MSMEG_4731|M.smegmatis_MC2_155 WVHGENVCAGYWEQSERTETTFGASIDS------PSAGTPTGPWLRTGDL
MLBr_00100|M.leprae_Br4923 WLHGNNLGTGYWGKEEESAQTFNNILKSRISESRAEGASDDASWVRTGDY
MMAR_1170|M.marinum_M WVRGPNISRGYFNGAGASQDCFGNVAGQ-------------GQYLRTGDL
MUL_1117|M.ulcerans_Agy99 WLTGRSVAKGYWGRDIQTEEVFAARLPG-----------DPARYLRTGDL
MAV_4122|M.avium_104 WLAGPSKGRGYWNRPQLTAEMFEARLAG----------DDEHSYLRTGDL
*: . . ** * ::****
TH_4458|M.thermoresistible__bu GFLLDGELFVTGRLKDLIIIRGRNYHPNDIEATVQEVHPALMSGRGAAFA
Mvan_0999|M.vanbaalenii_PYR-1 GFVDDGELFVIGRLNDVIVIRGVNYYPHDIEYTVERSHPALQPDAGAVIG
MAB_3579c|M.abscessus_ATCC_199 GTLVDGNLFITGRTKDVIIVNGRNLYAHDIEAAARAAAPALARGVGAAFA
Mb2974c|M.bovis_AF2122/97 GVIFEGELFITGRIKELLVVDGANHYPEDIEATIQEITGGR----VVAIA
Rv2950c|M.tuberculosis_H37Rv GVIFEGELFITGRIKELLVVDGANHYPEDIEATIQEITGGR----VVAIA
Mflv_0402|M.gilvum_PYR-GCK GFVHGGELFIVGRIKDLLIIRGRNHYPEDIEATVQGITRGR----VAAIS
MSMEG_4731|M.smegmatis_MC2_155 GFVSGGELFIVGRIKDVVIIRGRNHYPDDIEATVQEITRAR----AAAIS
MLBr_00100|M.leprae_Br4923 GTYFKDHLYIAGRIKDLVIIDGRNHYPQDLEYTAQESTKALRVGYVAAFS
MMAR_1170|M.marinum_M GFVQDGDLYVTGRLKDLVIVRGVNHYPQDIEFSVEQSHPAIRPGYCAAFT
MUL_1117|M.ulcerans_Agy99 GFCRDDELFVVGRLKDLVIVHGANHYPQDLEETAEGAHPAVRSHFVAVFA
MAV_4122|M.avium_104 GFLYEGELFVCGRSKDLIIVRGVNCYPSDIEAVVERSAKQVRGGCVAALS
* ..*:: ** :::::: * * :. *:* . ..:
TH_4458|M.thermoresistible__bu VSPDPSGTEQLVIVQEVDRGRLGEVDTDELIAAIRT--------------
Mvan_0999|M.vanbaalenii_PYR-1 VER--SGRVDLVSVSEIRRDLVDSIVGDDIVDAIRR--------------
MAB_3579c|M.abscessus_ATCC_199 VGT----PERLVLVHEIRPENLGDASLDDVLAAVRT--------------
Mb2974c|M.bovis_AF2122/97 VPD--DRTEKLVTIIELMKRGRTDEEEKNRLRTVKR--------------
Rv2950c|M.tuberculosis_H37Rv VPD--DRTEKLVTIIELMKRGRTDEEEKNRLRTVKR--------------
Mflv_0402|M.gilvum_PYR-GCK VPE--NSTEKLVTVIELKKSAEPDADATRWLSEVKS--------------
MSMEG_4731|M.smegmatis_MC2_155 VDR--DDAEHLVVIAEVRENQNPDVSPAEYLADLEG--------------
MLBr_00100|M.leprae_Br4923 VPA--NQLAQVVLEDPHVGLKFDAEDTSEQLVIVGERAAGTHKLDYQPIV
MMAR_1170|M.marinum_M LEVD--GEERLGVAAEIAADDPAQDTLESAMDSILQ--------------
MUL_1117|M.ulcerans_Agy99 EER--EDREALIVVAEIRREAERGLDPRDVGQRIAR--------------
MAV_4122|M.avium_104 VEQ--DDQEALVVVAEVRDEHNLPDARALAR-------------------
:
TH_4458|M.thermoresistible__bu -----AVTSQHDIGVHTVVLVDPLRIPTTSSGKIRRRTCRQRFLDGELDA
Mvan_0999|M.vanbaalenii_PYR-1 -----AVARDHQLALQRVVLLRPGGMPKTSSGKIQRARCRDELGRSGLPV
MAB_3579c|M.abscessus_ATCC_199 -----AIFAEFATPLSDLVLVAKGEVARTTSGKIRRTHMRASYEGGRITA
Mb2974c|M.bovis_AF2122/97 -EVASAISRSHRLRVADVVMVAPGSIPVTTSGKVRRSASVERYLHHEFSR
Rv2950c|M.tuberculosis_H37Rv -EVASAISRSHRLRVADVVMVAPGSIPVTTSGKVRRSASVERYLHHEFSR
Mflv_0402|M.gilvum_PYR-GCK -DITSAISNAHGLNVEDLVLVPPGSIPTTTSGKVRRSACVDHYRQDQFDR
MSMEG_4731|M.smegmatis_MC2_155 -EVVAAVSRSHGIIPADLVLVRRGAIPITTSGKVRRASCAEQYRDDTFAR
MLBr_00100|M.leprae_Br4923 DDIRAAIAVRHGVAVRDVLLVPAGTIPRTSSGKIGRRACRAAYIDGSLRS
MMAR_1170|M.marinum_M -----AITSHHEVVPYRLVLLARGAIPKTSSGKIQRQLCKQLLLTDQLPI
MUL_1117|M.ulcerans_Agy99 -----AITREHEVSVDAVFLARCGEVPKTTSGKIQRSLCRELLRQGGLAL
MAV_4122|M.avium_104 -----AIRRHCHIDPHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGALPT
*: :.: :. *:***: * :
TH_4458|M.thermoresistible__bu FAEWRLATPRPAQPVPAADEQADEQAGAGPGAGPGADEIRAWFVAQLAGE
Mvan_0999|M.vanbaalenii_PYR-1 VHDWQASPAR------QATIDFDLESLSQPGM------LERQLADWLRQE
MAB_3579c|M.abscessus_ATCC_199 FADPRLASAG-----------------------------G----------
Mb2974c|M.bovis_AF2122/97 LDAMA---------------------------------------------
Rv2950c|M.tuberculosis_H37Rv LDAMA---------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK LDA-----------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 LVHA----------------------------------------------
MLBr_00100|M.leprae_Br4923 GASSPTVFAAEF--------------------------------------
MMAR_1170|M.marinum_M LGDRVSTATIS--------------STPQQPDGGARSPKYRAMEQYLLEL
MUL_1117|M.ulcerans_Agy99 HGALEK--------------------------------------------
MAV_4122|M.avium_104 FSSWVNPAATRGHDGTAAGAGPLERFANLIESYDLTGDEDCSFADLGIDS
TH_4458|M.thermoresistible__bu LGLSPDDIDTGQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPTI
Mvan_0999|M.vanbaalenii_PYR-1 LSIS--DLTWSTPLTELGIDSLKGVELVNVLSAAFDFTFPPTSMLDHPSI
MAB_3579c|M.abscessus_ATCC_199 -------------------DVVR---------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M LNLSPEELESGNNLAAYGFDSIDGAALAKKIKADWGIEVPMEILPLLTIR
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 LALAELRNDMQALLAEHGAAELADEVNTRLLQR---LTVAEFFSLIRQFG
TH_4458|M.thermoresistible__bu DLAAEHLAGLTHTATSTAADAGVSTGAGRRPEHGPAPDRADEPIAIIGIG
Mvan_0999|M.vanbaalenii_PYR-1 AS----LAGLIRDAKLGAGHRAASN----RPDAG----------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M DLVDTLAN------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 EGSGQPLDALRRALDQISAEYEAHEAAQMRADAALPLPDPAPARAGTPTD
TH_4458|M.thermoresistible__bu CRFPGADGPAAYWRLLREGRDAITATPPERWDTDSVGDGTRWGGFLERID
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------VYSAG----------QID
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 ILLTGATGFLGPFLLSSLLARTPYTVHALVRATDPGHGLDRIVASLRKAQ
TH_4458|M.thermoresistible__bu GFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDRLAGSRTGVF
Mvan_0999|M.vanbaalenii_PYR-1 ALD---------EAALVDLLQQR--------------VDDILDGGRS---
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 LWTPALEAEVRARVRVICGDLAEPALGIGEPAFARLARDVDAVVHNGALV
TH_4458|M.thermoresistible__bu TGVSTYDYLHLQLSHPELIDAYSGTGTASSIAANRLSYVFDFRGPSLTLD
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 NYVRTYDALRPTNVEGTRELLRLAMTDHAKTFHLVSSTFIYGWSTQPVVG
TH_4458|M.thermoresistible__bu SACSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLNFTRAGVMAT
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 EWDANEKMAGLDFGYSQTKWVAEQLALAAQRKGLDVRIYRPSLISPTRSG
TH_4458|M.thermoresistible__bu DGRCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAVIRGSAVNQD
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 FGSQDDILVRLTAFMIEHGLAVNALNQISLLPADLIADHIVALMDLPDES
TH_4458|M.thermoresistible__bu GRTNGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGIGTPVGDAIEV
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 GSVFNMTADDYYNLTDVTRILSERYGYRFDYHDIDSFAEQLNRRCTPDDQ
TH_4458|M.thermoresistible__bu GALGTVLAEDRPPDSPCLIGSVKTNIGHLEAAAGIAGLIKVALALRHRMI
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 MYPLVDFLTRSADKIAAMRDKRYDNTQYRHRRGLVPVRLREPALTETVDH
TH_4458|M.thermoresistible__bu PPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDSGRAVAGVSAFGFGGTNA
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 LVRFLRTERMITEVEDEAQRSA----------------------------
TH_4458|M.thermoresistible__bu HVVLAEAPQVRAAATADDHADGFVEILPLSARSQAALDALAERYESALTG
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu GVPPADLCHTAGARRAHHDHRLAVVGASRAELIGALAAYRRGEPHPGVFT
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu GRSQSGHRSGVVFVFSDEGSQWRGMAQRLYAEDQVFRTALAECDRALRRH
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu MEISPLSELLADPSHSRMDEVTIASPALFAVQVALAALWQSWGVEPAAVI
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu GHRMGEVAAAHVAGVLGLDDAAALLCGRTRLSRLASTGAVREGLDGLLAN
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu LRPDDPRIPLYSTVTGDAVTGRGFGAAHWMENLHSPVRFSAAVRRLLGRG
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu HDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGECGRDVLMTSLAA
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu LYASGHAVDWARVHPHGSHCTAAPTYPWQRQRFWLDIDRCDTGDGAGTGG
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu TAERTVVPAPLPAPSASAAPTVDEVLLCADQRERRELLESYLRDRVAAEL
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu GVLPPLLDVAAPLSTLGIDSLTAAELRARVERDLGIVIPVAQLLNGPSVS
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu DLAEWISTTMVGFGSTTPEPESAGVPGRSRPPDGAVASGSGDGGRWIELL
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2974c|M.bovis_AF2122/97 --------------------------------------------------
Rv2950c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00100|M.leprae_Br4923 --------------------------------------------------
MMAR_1170|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
MAV_4122|M.avium_104 --------------------------------------------------
TH_4458|M.thermoresistible__bu NQMPEVSDDTVDELLRQLLAAGENHDDTQLH
Mvan_0999|M.vanbaalenii_PYR-1 -------------------------------
MAB_3579c|M.abscessus_ATCC_199 -------------------------------
Mb2974c|M.bovis_AF2122/97 -------------------------------
Rv2950c|M.tuberculosis_H37Rv -------------------------------
Mflv_0402|M.gilvum_PYR-GCK -------------------------------
MSMEG_4731|M.smegmatis_MC2_155 -------------------------------
MLBr_00100|M.leprae_Br4923 -------------------------------
MMAR_1170|M.marinum_M -------------------------------
MUL_1117|M.ulcerans_Agy99 -------------------------------
MAV_4122|M.avium_104 -------------------------------