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MFLEDLLSRRLRRHADEFPDERILSFLDDRLEVADSLTFGRLDDRARSVAAGLLDRGMGGAPVVLSYPPG LDFVSAFCGCLYAGAIAVPAALPQSRRTAERLAAVLKDSAARCVLTSAAHRAELYSHAGAAPSVVDVIAT DVLPSRPGDGRVALPDPDQVAFLQYTSGSTRSPRGVMVRHGDLAANLNSLREILAFDDHATGVSWLPVFH DMGLIAGVLLPIWSARPQFLMAPATFVRNPLSWLEAISRYGGTHQGAPNFGYQACVDAARAAGATTFDLR NWRVAWNGAEPVRPDTLHQFRDQFALNGFGSECLSPGYGLAEATLVVSGSDGSKPATELTVDESELHVGQ VRPRIDDGPGVKRLVGSGRPAAGTEVQIVRADGRVAEPHTLGEIWVRSDSVAQGYWNNPGETSGTFGACL TTGEGPYLRTGDLGFVDDGELFVIGRLNDVIVIRGVNYYPHDIEYTVERSHPALQPDAGAVIGVERSGRV DLVSVSEIRRDLVDSIVGDDIVDAIRRAVARDHQLALQRVVLLRPGGMPKTSSGKIQRARCRDELGRSGL PVVHDWQASPARQATIDFDLESLSQPGMLERQLADWLRQELSISDLTWSTPLTELGIDSLKGVELVNVLS AAFDFTFPPTSMLDHPSIASLAGLIRDAKLGAGHRAASNRPDAGVYSAGQIDALDEAALVDLLQQRVDDI LDGGRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0999 | - | - | 100% (706) | AMP-dependent synthetase and ligase |
| M. vanbaalenii PYR-1 | Mvan_3127 | - | 9e-87 | 35.52% (563) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_0272 | - | 9e-82 | 35.69% (566) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1217c | fadD21 | 4e-85 | 36.27% (568) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_0402 | - | 4e-87 | 36.20% (569) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv1185c | fadD21 | 4e-85 | 36.27% (568) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_00138 | fadD28 | 2e-85 | 36.04% (566) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_3579c | - | 3e-95 | 39.22% (538) | putative acyl-CoA synthase/polyketide synthase |
| M. marinum M | MMAR_0468 | - | 1e-105 | 41.13% (564) | fatty-acid-CoA ligase |
| M. avium 104 | MAV_1328 | - | 5e-84 | 35.97% (581) | acyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_4731 | - | 1e-85 | 37.63% (566) | acyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_4458 | - | 1e-122 | 39.57% (690) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
| M. ulcerans Agy99 | MUL_1117 | - | 1e-105 | 41.62% (567) | fatty-acid-CoA ligase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0468|M.marinum_M MNESIPGGRVAHLPPPHLNLVERLAWRARNQPDELAMVELRGMRGETDK-
MUL_1117|M.ulcerans_Agy99 ---------MAHLPPPHLNLVERLAWRARNQPDELAMVELRGMCGETDK-
Mvan_0999|M.vanbaalenii_PYR-1 ------------MFLEDL-LSRRLRRHADEFPDERILSFLDDRLEVADS-
TH_4458|M.thermoresistible__bu -------------------LLSLLRQRSERYGDKIAFDYCTGEQ-EHSR-
MAB_3579c|M.abscessus_ATCC_199 ----------MQTTYDFTDYFSTVTEWVARQPDQIALGYLEEGAGELTER
Mb1217c|M.bovis_AF2122/97 --------------MSDSSVLSLLRERAGLQPDDAAFTYIDYEQDWAGIT
Rv1185c|M.tuberculosis_H37Rv --------------MSDSSVLSLLRERAGLQPDDAAFTYIDYEQDWAGIT
MAV_1328|M.avium_104 --------------MHGSSVVSLLRERAGLQPDDVAFRYTDYEQDWAGVA
MLBr_00138|M.leprae_Br4923 --------------MSVRSIPAVLRTCARLQPNDPVFTFMDYEQDWDGVK
Mflv_0402|M.gilvum_PYR-GCK ----------------------MLHGRASMRPDDVAFTFTEYADDPAGVA
MSMEG_4731|M.smegmatis_MC2_155 --------------MTRSSVIGVLRERASLQPGDVAFTFIDYDTDPEGVA
: .. :
MMAR_0468|M.marinum_M --ATYARLDARARAIAFQLKSLGNQGDRVLLVMGNCLDYVVGFLACAYAR
MUL_1117|M.ulcerans_Agy99 --ATYARLDARARAIAFQLKSLGNQGDRVLLVMGHCLDYVVGFLACAYAR
Mvan_0999|M.vanbaalenii_PYR-1 --LTFGRLDDRARSVAAGLLDRGMGGAPVVLSYPPGLDFVSAFCGCLYAG
TH_4458|M.thermoresistible__bu --LTYQELDIRARAIAAHLQDQGVAGERVLVLCPSGLDFITAMFGCFYVG
MAB_3579c|M.abscessus_ATCC_199 A-WTYAELVSHATAVAARLREDLEPGDRTLLLYPPGLPFVAAFLGCLAAG
Mb1217c|M.bovis_AF2122/97 ETLTWSEVFRRTRIVAHEVRRHCTTGDRAVILAPQGLAYIAAFLGSMQAG
Rv1185c|M.tuberculosis_H37Rv ETLTWSEVFRRTRIVAHEVRRHCTTGDRAVILAPQGLAYIAAFLGSMQAG
MAV_1328|M.avium_104 ETLTWAQLYQRTSNLAREVARHGDTGDRAVILAPQGLSYIVAFLAAIQAG
MLBr_00138|M.leprae_Br4923 ITLTWSQLYRRTLNVAQELNRCGSTGDRVAISAPQGLDYVVAFLGALQAG
Mflv_0402|M.gilvum_PYR-GCK ETVTWSQLSRRTANVARVLARHGSAGDRAVILAPQGLEYILAFLGSMQAG
MSMEG_4731|M.smegmatis_MC2_155 HTLTWSQLNRRVQSLAYEMQARSAVGDRAVILAPQGLDYVVAFLASLQAG
*: .: :. :* : * . : * :: .: .. .
MMAR_0468|M.marinum_M RVAVNLPVPR-RAKHLDRLAHVVADCGAEVLLTSGPEAKELTVSVAADLR
MUL_1117|M.ulcerans_Agy99 RVAVNLPVPR-RAKHLDRLAHVVADCGAEVLLTSGPEAKELTASVAADLR
Mvan_0999|M.vanbaalenii_PYR-1 AIAVPAALPQ-SRRTAERLAAVLKDSAARCVLTSAAHRAELYSHAGAAP-
TH_4458|M.thermoresistible__bu AVAVPVHPPV-HNRLLSRVASIVADVRATSVLTTAATRADLKEILDGLHD
MAB_3579c|M.abscessus_ATCC_199 VVAVPAPLPDGRDKAQHRLAGIIADAGTRVVLTESSVAPLIAGWADALP-
Mb1217c|M.bovis_AF2122/97 AIAVPLSVPQ-IGSHDERVSAVLADASPSVILTTSAVAEAVAEHIHRPNT
Rv1185c|M.tuberculosis_H37Rv AIAVPLSVPQ-IGSHDERVSAVLADASPSVILTTSAVAEAVAEHIHRPNT
MAV_1328|M.avium_104 LIAVPLSVPQ-PGSHDERVSAVLADTGPAVVLTTAAAAATVTEYLRRPDT
MLBr_00138|M.leprae_Br4923 RIAVPLSVPQ-GGVTDERFESVLNDSSPVAILTTSPAVDDVVHHVTQRPD
Mflv_0402|M.gilvum_PYR-GCK MIAVPLPLPH-RGSNHDRVSAVFTDTTPAVVLTTSAVAGDVGAYVDEARM
MSMEG_4731|M.smegmatis_MC2_155 RIGVPLSVPF-PGVHDDRVTAVLRDTAPSIVLTTSAVSSHIAEYLEPQAG
:.* * *. :. * . :** .. :
MMAR_0468|M.marinum_M LDFLTVLRLDWLLAIPDE---DWQPVAPASKDVCLLQYTSGSTSAPRGVV
MUL_1117|M.ulcerans_Agy99 LDFLTVLRLDWLLAIPDE---DWQPVAPASKDVCLLQYTSDSTSAPRGVV
Mvan_0999|M.vanbaalenii_PYR-1 -SVVDVIATDVLPSRPG----DGRVALPDPDQVAFLQYTSGSTRSPRGVM
TH_4458|M.thermoresistible__bu GDPLRWLAVDTIEADDET---SWTPTTVDTDSVAFVQYTSGSTSTPKGVV
MAB_3579c|M.abscessus_ATCC_199 -TPIALIATDAIPVELGR---EFVPVRSAPSDTAFLQYTSGSTNAPKGVI
Mb1217c|M.bovis_AF2122/97 NNVGPIIEIDSLDLTG----NSPSFRVKDLPSAAYLQYTSGSTRAPAGVM
Rv1185c|M.tuberculosis_H37Rv NNVGPIIEIDSLDLTG----NSPSFRVKDLPSAAYLQYTSGSTRAPAGVM
MAV_1328|M.avium_104 GPAPAVVEIDSLDLDEP---NSASIRISGAPDIAYLQYTSGSTRLPAGVM
MLBr_00138|M.leprae_Br4923 ESTPSIIEVDLLDLDSP---NGSGDGNGDHLSTAYLQYTSGSTRTPAGVM
Mflv_0402|M.gilvum_PYR-GCK QIAPTIVTVDTLDLDGTPSDDEPAVAAGEAPDIAYLQYSSGSTRLPTGVM
MSMEG_4731|M.smegmatis_MC2_155 QAAPWIAEIDTLDLDTR----RRPVKREQAPETAYLQYTSGSTRTPAGVM
* : . . :**:*.** * **:
MMAR_0468|M.marinum_M VTHDNLMFNCAQIQYGFGLTA------EDRALSWLPLYHDMGLILGVLTP
MUL_1117|M.ulcerans_Agy99 VTHDNLMFNCAQIQYGFGLTA------EDRALSWLPLYHDMGLILGVLTP
Mvan_0999|M.vanbaalenii_PYR-1 VRHGDLAANLNSLREILAFDD------HATGVSWLPVFHDMGLIAGVLLP
TH_4458|M.thermoresistible__bu LTHHNLLANLESISRDAGQGD------EARVVSWLPLHHDMGLIGGIFGV
MAB_3579c|M.abscessus_ATCC_199 VTHGNLVHNEQELGARIENDP------SFSMLSWLPQFHDMGLIGMLLWP
Mb1217c|M.bovis_AF2122/97 ISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAP
Rv1185c|M.tuberculosis_H37Rv ISHRNLQANFQQLMSNYFGDRNGVAPPDTTIVSWLPFYHDMGLVLGIIAP
MAV_1328|M.avium_104 VSHRNLQVNFQQLMAAFFPDVDGVAPRDTVCVSWLPFYHDMGLVQGVIAP
MLBr_00138|M.leprae_Br4923 ISHHNLRANFEQLMSTYLADTDGVFPVGGMSVSWLPFYHDMGLILGVCVP
Mflv_0402|M.gilvum_PYR-GCK ISHRNLQSNYEQLMRSFFAVPHIRSTAELTIVSWLPFYHDMGLVLGVCAP
MSMEG_4731|M.smegmatis_MC2_155 VSHRNLTANFEQVVAGFFPDN--IAPSDTTSISWLPLYHDMGLMLGLCAP
: * :* * .: :**** .*****: :
MMAR_0468|M.marinum_M IFAGFPVVLADPLSFVKRPDLWLRAISDYRITFTGGPNFAYDLCADAASY
MUL_1117|M.ulcerans_Agy99 IFAGFPVVLADPLSFVKRPDLWLRAISDYRITFTGGPNFAYDLCADAASY
Mvan_0999|M.vanbaalenii_PYR-1 IWSARPQFLMAPATFVRNPLSWLEAISRYGGTHQGAPNFGYQACVDAARA
TH_4458|M.thermoresistible__bu VHFGGTAYLMPPSSFIQRPMSWLEAISWHGANISVGPNFGYQLCVERSTP
MAB_3579c|M.abscessus_ATCC_199 LFYGGTSRFLSPVTFIKHPIQWIRAMSKYRATVGVAPNFAFDLVARRCTH
Mb1217c|M.bovis_AF2122/97 ILGGYRSELTSPLAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTD
Rv1185c|M.tuberculosis_H37Rv ILGGYRSELTSPLAFLQRPARWLHSLANGSPSWSAAPNFAFELAVRKTTD
MAV_1328|M.avium_104 ILGGYPADLTSPVAFLQRPARWIQAMSRADPVFSAAPNFAFELAVRKTTD
MLBr_00138|M.leprae_Br4923 ILGGCPAVLTSPVSFLQRPARWMHMLASEFPVFSAAPNFAFELATKKISD
Mflv_0402|M.gilvum_PYR-GCK ILGGHPAKLTSPVAFLEKPSRWVRALAENPQAFSAAPNFAFELAARKTRD
MSMEG_4731|M.smegmatis_MC2_155 VLGGWHTVLISPFAFLAKPARWMQLLATHPATVTAAPNFAFDLAARKTSD
: . : * :*: .* *:. :: .***.:: .
MMAR_0468|M.marinum_M ADLSGIDLSCWNVALNGAEPIRATTLERFNAALAPLGWAPTYMQPSYGLA
MUL_1117|M.ulcerans_Agy99 TDLSGIDLSCWNVALNGAEPIRATTLERFNAALAPLGWAPTCMQPSYGLA
Mvan_0999|M.vanbaalenii_PYR-1 AGATTFDLRNWRVAWNGAEPVRPDTLHQFRDQFALNGFGSECLSPGYGLA
TH_4458|M.thermoresistible__bu EERATLDLSTWVRAYCGAEPVRAATMRRFTEAFAPAGFRADAFHPVYGLA
MAB_3579c|M.abscessus_ATCC_199 EALEGVDLSCVRSLLNGSEPVQWASIERFTTLLAPFGLAEHAVTPVYGLA
Mb1217c|M.bovis_AF2122/97 ADIEGLDLGNVLGITSGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLA
Rv1185c|M.tuberculosis_H37Rv ADIEGLDLGNVLGITSGAERVHPNTLSRFCNRFAPYNFREDMIRPSYGLA
MAV_1328|M.avium_104 ADLAGVNLGNIISIVSGAERIHPATLRRFCKRFAPYNFREHMMQPSYGLA
MLBr_00138|M.leprae_Br4923 DDMIGVDLGNIHIILNGSERVQPATIKRFNNRFARFNLKEKAVRPSYGLA
Mflv_0402|M.gilvum_PYR-GCK SDLAGLDLGGVLGIINGAERVNPATLERFADRFAHFNFRDNMLRPSYGLA
MSMEG_4731|M.smegmatis_MC2_155 ADLTGMDLGDVRCVLSGSERVHEPTLRRFSDRFAAFNLHEQALRPSYGLA
.:* *:* :. :: :* :* . . * ****
MMAR_0468|M.marinum_M ENTLAVSTKIPATEPTVVEIDVAALRQSQVCAPRGDSP-SRRLVSSGRIL
MUL_1117|M.ulcerans_Agy99 ENTLAVSTKIPATEPTVVEIYVAALRQSQVCAPRGDSP-SRRLVSSGRIL
Mvan_0999|M.vanbaalenii_PYR-1 EATLVVSGSDGSKPATELTVDESELHVGQVRPRIDDGPGVKRLVGSGRPA
TH_4458|M.thermoresistible__bu EATLFVSGRPENVLPTVRSLDNAALREHRVVPAAADDANAAAVVGCGPAA
MAB_3579c|M.abscessus_ATCC_199 EATLFVTGDPHGTPVTTAVVDGEALAENRLVVANEGAPRSRVLVASGR-I
Mb1217c|M.bovis_AF2122/97 EATLYVASRNSGDKPEVVYFEPDKLSTGSANR---CEPKTGTPLLSYGMP
Rv1185c|M.tuberculosis_H37Rv EATLYVASRNSGDKPEVVYFEPDKLSTGSANR---CEPKTGTPLLSYGMP
MAV_1328|M.avium_104 EATVYVASRAEAGAPEVVHFEPEKLSAGSAQR---CPAQTGSPLLSYGAP
MLBr_00138|M.leprae_Br4923 EATVYVATSRSGQPAELVDFDAESLSTGQAKT---CTSGNGTSLISYVLP
Mflv_0402|M.gilvum_PYR-GCK EATVFVASGIYRESADEARFDSNELSAGRVAR---RTTG-GTALVNYTLP
MSMEG_4731|M.smegmatis_MC2_155 EATLFVATRETGHPPKVARFAAQELSDGRAVP---CDDENGTALVSYGMP
* *: *: . * :
MMAR_0468|M.marinum_M AGTMVKIVDPETGHPVGPDRVGEIWLTGRSVAKGYWGRDIQTEEVFAARL
MUL_1117|M.ulcerans_Agy99 AGTMVKIVDPETGHPVGPDRVGEIWLTGRSVAKGYWGRDIQTEEVFAARL
Mvan_0999|M.vanbaalenii_PYR-1 AGTEVQIVR-ADGRVAEPHTLGEIWVRSDSVAQGYWNNPGETSGTFGACL
TH_4458|M.thermoresistible__bu YGEEIVIVDPATRREFPPDVVGEIWVAGENVAQGYLGKPSESAETFAAHL
MAB_3579c|M.abscessus_ATCC_199 GGIEVSVVG-ADGAPLPDGEIGEIWLRGTSVAAGYWNLPELSAEIFGATP
Mb1217c|M.bovis_AF2122/97 TSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNKPDETRHTFGAML
Rv1185c|M.tuberculosis_H37Rv TSPTVRIVDPDTCIECPAGTIGEIWVKGDNVAEGYWNKPDETRHTFGAML
MAV_1328|M.avium_104 TSPTVRIVDPDTNTERADGTVGEIWVNGENVAQGYWRKPEETRRTFGGVL
MLBr_00138|M.leprae_Br4923 PSPIVRIVDSDTCIQCQDGTVGEIWVHGDNVADGYWQKPDESERTFGGKI
Mflv_0402|M.gilvum_PYR-GCK QAPTVRIVDVETNRECASDVVGEIWVHGENVAAGYWSRPADEQQCFGATL
MSMEG_4731|M.smegmatis_MC2_155 ESPTVRIVDPQTRAECPTGIVGEIWVHGENVCAGYWEQSERTETTFGASI
. : :* :****: . .*. ** *..
MMAR_0468|M.marinum_M P-----GDPARYLRTGDLGFCRDDELFVVGRLKDLVIVHGANHYPQDLEE
MUL_1117|M.ulcerans_Agy99 P-----GDPARYLRTGDLGFCRDDELFVVGRLKDLVIVHGANHYPQDLEE
Mvan_0999|M.vanbaalenii_PYR-1 T-----TGEGPYLRTGDLGFVDDGELFVIGRLNDVIVIRGVNYYPHDIEY
TH_4458|M.thermoresistible__bu AD----SGRGPFLRTGDYGFLLDGELFVTGRLKDLIIIRGRNYHPNDIEA
MAB_3579c|M.abscessus_ATCC_199 I-----GGTGGWLRTGDLGTLVDGNLFITGRTKDVIIVNGRNLYAHDIEA
Mb1217c|M.bovis_AF2122/97 VHPSAGTPDGSWLRTGDLGFLSEDEMFIVGRMKDMLIVYGRNHYPEDIES
Rv1185c|M.tuberculosis_H37Rv VHPSAGTPDGSWLRTGDLGFLSEDEMFIVGRMKDMLIVYGRNHYPEDIES
MAV_1328|M.avium_104 VNPSPGTPRQPWLRTGDLGFISAGELFIVGRMKDLLIVYGRNHYPEDIES
MLBr_00138|M.leprae_Br4923 AAPSRGTPEGPWLRTGDSGFVIDGKMFIIGRIKDLLIVYGRNHSPDDIEG
Mflv_0402|M.gilvum_PYR-GCK ADPSPGTPAGPWLRTGDLGFVHGGELFIVGRIKDLLIIRGRNHYPEDIEA
MSMEG_4731|M.smegmatis_MC2_155 DSPSAGTPTGPWLRTGDLGFVSGGELFIVGRIKDVVIIRGRNHYPDDIEA
:***** * .::*: ** :*:::: * * ..*:*
MMAR_0468|M.marinum_M TAEGAHPAVRSHFVAVFAE--EREDREALIVVAEIRREAERGLDPRDVGQ
MUL_1117|M.ulcerans_Agy99 TAEGAHPAVRSHFVAVFAE--EREDREALIVVAEIRREAERGLDPRDVGQ
Mvan_0999|M.vanbaalenii_PYR-1 TVERSHPALQPDAGAVIGV--ERSGRVDLVSVSEIRRDLVDSIVGDDIVD
TH_4458|M.thermoresistible__bu TVQEVHPALMSGRGAAFAVSPDPSGTEQLVIVQEVDRGRLGEVDTDELIA
MAB_3579c|M.abscessus_ATCC_199 AARAAAPALARGVGAAFAVG----TPERLVLVHEIRPENLGDASLDDVLA
Mb1217c|M.bovis_AF2122/97 TVQEITGGRVAAISVPVDH------TEKLVTVIELKLLGDSAGEAMDELD
Rv1185c|M.tuberculosis_H37Rv TVQEITGGRVAAISVPVDH------TEKLVTVIELKLLGDSAGEAMDELD
MAV_1328|M.avium_104 TVQAVTGGRVAAISVPADE------TEKLVTIIELKRRGDSDEDARRKLD
MLBr_00138|M.leprae_Br4923 TIQEITRGRCAAISVPDRN------TEKLVAIIELKKLGDADQYAMDRLG
Mflv_0402|M.gilvum_PYR-GCK TVQGITRGRVAAISVPENS------TEKLVTVIELKKSAEPDADATRWLS
MSMEG_4731|M.smegmatis_MC2_155 TVQEITRARAAAISVDRDD------AEHLVVIAEVRENQNPDVSPAEYLA
: . . . *: : *:
MMAR_0468|M.marinum_M RIA----RAITREHEVSVDAVFLARCGEVPKTTSGKIQRSLCRELLRQGG
MUL_1117|M.ulcerans_Agy99 RIA----RAITREHEVSVDAVFLARCGEVPKTTSGKIQRSLCRELLRQGG
Mvan_0999|M.vanbaalenii_PYR-1 AIR----RAVARDHQLALQRVVLLRPGGMPKTSSGKIQRARCRDELGRSG
TH_4458|M.thermoresistible__bu AIR----TAVTSQHDIGVHTVVLVDPLRIPTTSSGKIRRRTCRQRFLDGE
MAB_3579c|M.abscessus_ATCC_199 AVR----TAIFAEFATPLSDLVLVAKGEVARTTSGKIRRTHMRASYEGGR
Mb1217c|M.bovis_AF2122/97 VIKNNVTAAISRSHGLNVADLVLVPPGSIPTTTSGKIRRAACVEQYRLQQ
Rv1185c|M.tuberculosis_H37Rv VIKNNVTAAISRSHGLNVADLVLVPPGSIPTTTSGKIRRAACVEQYRLQQ
MAV_1328|M.avium_104 AVKNEVTAAISIAHGLNVADLVPVAPGSIPTTTSGKIRRAACVERYLRGA
MLBr_00138|M.leprae_Br4923 AIKREVISALSNSHGLSVSDVVLVAPGSIPITTSGKVRRSTCVERYRQDQ
Mflv_0402|M.gilvum_PYR-GCK EVKSDITSAISNAHGLNVEDLVLVPPGSIPTTTSGKVRRSACVDHYRQDQ
MSMEG_4731|M.smegmatis_MC2_155 DLEGEVVAAVSRSHGIIPADLVLVRRGAIPITTSGKVRRASCAEQYRDDT
: *: . :. :. *:***::*
MMAR_0468|M.marinum_M -----------------------LALHGALEK------------------
MUL_1117|M.ulcerans_Agy99 -----------------------LALHGALEK------------------
Mvan_0999|M.vanbaalenii_PYR-1 LPVVHDWQASPARQATIDFDLESLSQPGMLERQ------------LADWL
TH_4458|M.thermoresistible__bu LDAFAEWRLATPRPAQPVPAADEQADEQAGAGPGAGPGADEIRAWFVAQL
MAB_3579c|M.abscessus_ATCC_199 ITAFADPR---------------LASAGGDVVR-----------------
Mb1217c|M.bovis_AF2122/97 FTRLDG--------------------------------------------
Rv1185c|M.tuberculosis_H37Rv FTRLDG--------------------------------------------
MAV_1328|M.avium_104 FIRLDG--------------------------------------------
MLBr_00138|M.leprae_Br4923 FDRLDA--------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK FDRLDA--------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 FARLVHA-------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 RQELSIS--DLTWSTPLTELGIDSLKGVELVNVLSAAFDFTFPPTSMLDH
TH_4458|M.thermoresistible__bu AGELGLSPDDIDTGQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDH
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 PSIASLAGLIR-------------DAKLGAG----HRAASNRPDAGVYSA
TH_4458|M.thermoresistible__bu PTIDLAAEHLAGLTHTATSTAADAGVSTGAGRRPEHGPAPDRADEPIAII
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 GQ----IDALDEAALVDLLQQR-------------VDDILDGGRS-----
TH_4458|M.thermoresistible__bu GIGCRFPGADGPAAYWRLLREGRDAITATPPERWDTDSVGDGTRWGGFLE
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu RIDGFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDRLAGSRT
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu GVFTGVSTYDYLHLQLSHPELIDAYSGTGTASSIAANRLSYVFDFRGPSL
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu TLDSACSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLNFTRAGV
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu MATDGRCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAVIRGSAV
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu NQDGRTNGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGIGTPVGDA
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu IEVGALGTVLAEDRPPDSPCLIGSVKTNIGHLEAAAGIAGLIKVALALRH
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu RMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDSGRAVAGVSAFGFGG
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu TNAHVVLAEAPQVRAAATADDHADGFVEILPLSARSQAALDALAERYESA
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu LTGGVPPADLCHTAGARRAHHDHRLAVVGASRAELIGALAAYRRGEPHPG
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu VFTGRSQSGHRSGVVFVFSDEGSQWRGMAQRLYAEDQVFRTALAECDRAL
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu RRHMEISPLSELLADPSHSRMDEVTIASPALFAVQVALAALWQSWGVEPA
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu AVIGHRMGEVAAAHVAGVLGLDDAAALLCGRTRLSRLASTGAVREGLDGL
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu LANLRPDDPRIPLYSTVTGDAVTGRGFGAAHWMENLHSPVRFSAAVRRLL
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu GRGHDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGECGRDVLMTS
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu LAALYASGHAVDWARVHPHGSHCTAAPTYPWQRQRFWLDIDRCDTGDGAG
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu TGGTAERTVVPAPLPAPSASAAPTVDEVLLCADQRERRELLESYLRDRVA
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu AELGVLPPLLDVAAPLSTLGIDSLTAAELRARVERDLGIVIPVAQLLNGP
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M --------------------------------------------------
MUL_1117|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu SVSDLAEWISTTMVGFGSTTPEPESAGVPGRSRPPDGAVASGSGDGGRWI
MAB_3579c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1217c|M.bovis_AF2122/97 --------------------------------------------------
Rv1185c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1328|M.avium_104 --------------------------------------------------
MLBr_00138|M.leprae_Br4923 --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4731|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0468|M.marinum_M ----------------------------------
MUL_1117|M.ulcerans_Agy99 ----------------------------------
Mvan_0999|M.vanbaalenii_PYR-1 ----------------------------------
TH_4458|M.thermoresistible__bu ELLNQMPEVSDDTVDELLRQLLAAGENHDDTQLH
MAB_3579c|M.abscessus_ATCC_199 ----------------------------------
Mb1217c|M.bovis_AF2122/97 ----------------------------------
Rv1185c|M.tuberculosis_H37Rv ----------------------------------
MAV_1328|M.avium_104 ----------------------------------
MLBr_00138|M.leprae_Br4923 ----------------------------------
Mflv_0402|M.gilvum_PYR-GCK ----------------------------------
MSMEG_4731|M.smegmatis_MC2_155 ----------------------------------