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M. smegmatis MC2 155 MSMEG_4731 (-)

annotation: acyl-CoA synthetase
coordinates: 4829885 - 4831618
length: 577

MTRSSVIGVLRERASLQPGDVAFTFIDYDTDPEGVAHTLTWSQLNRRVQSLAYEMQARSAVGDRAVILAP
QGLDYVVAFLASLQAGRIGVPLSVPFPGVHDDRVTAVLRDTAPSIVLTTSAVSSHIAEYLEPQAGQAAPW
IAEIDTLDLDTRRRPVKREQAPETAYLQYTSGSTRTPAGVMVSHRNLTANFEQVVAGFFPDNIAPSDTTS
ISWLPLYHDMGLMLGLCAPVLGGWHTVLISPFAFLAKPARWMQLLATHPATVTAAPNFAFDLAARKTSDA
DLTGMDLGDVRCVLSGSERVHEPTLRRFSDRFAAFNLHEQALRPSYGLAEATLFVATRETGHPPKVARFA
AQELSDGRAVPCDDENGTALVSYGMPESPTVRIVDPQTRAECPTGIVGEIWVHGENVCAGYWEQSERTET
TFGASIDSPSAGTPTGPWLRTGDLGFVSGGELFIVGRIKDVVIIRGRNHYPDDIEATVQEITRARAAAIS
VDRDDAEHLVVIAEVRENQNPDVSPAEYLADLEGEVVAAVSRSHGIIPADLVLVRRGAIPITTSGKVRRA
SCAEQYRDDTFARLVHA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4731--100% (577)acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_0411-e-18055.96% (570) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_4301-e-10641.56% (563) acyl-CoA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1548fadD250.057.51% (579) acyl-CoA synthetase
M. gilvum PYR-GCKMflv_0402-0.055.77% (572) acyl-CoA synthetase
M. tuberculosis H37RvRv1521fadD250.057.51% (579) acyl-CoA synthetase
M. leprae Br4923MLBr_01234-0.056.50% (577) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_0935c-0.056.24% (569) acyl-CoA synthetase
M. marinum MMMAR_1180-0.059.06% (574) Fatty acyl-AMP ligase FadD28_1 and polyketide synthase
M. avium 104MAV_1328-0.056.33% (577) acyl-CoA synthetase
M. thermoresistible (build 8)TH_3603-1e-10439.82% (565) PUTATIVE acyl-CoA synthase
M. ulcerans Agy99MUL_2008fadD280.057.79% (578) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_0272-0.056.60% (576) acyl-CoA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1548|M.bovis_AF2122/97            ----------------MSVVESSLPGVLRERASFQPNDKALTFIDYERSW
Rv1521|M.tuberculosis_H37Rv         ----------------MSVVESSLPGVLRERASFQPNDKALTFIDYERSW
MUL_2008|M.ulcerans_Agy99           ----------------MSVR--SLPAALRACARLQPNDPAFTFMNYEQNW
MMAR_1180|M.marinum_M               ------------------MLDHSISAVLRERASLRPSETAFTFIDYERDW
MSMEG_4731|M.smegmatis_MC2_155      ------------------MTRSSVIGVLRERASLQPGDVAFTFIDYDTDP
MAB_0935c|M.abscessus_ATCC_199      --------------------------MLHGRASLRPDDIAFTFTDYTNSP
Mvan_0272|M.vanbaalenii_PYR-1       -----------------MTSQSSILSMLHGRASMRPGDVAFTFTDYAVDP
Mflv_0402|M.gilvum_PYR-GCK          --------------------------MLHGRASMRPDDVAFTFTEYADDP
MLBr_01234|M.leprae_Br4923          ------------------MQNSSVLSFLRERAGLQPDDEAFSFTDYEQDW
MAV_1328|M.avium_104                ------------------MHGSSVVSLLRERAGLQPDDVAFRYTDYEQDW
TH_3603|M.thermoresistible__bu      MAKFKLEDYLDAAGNIVMPEGITLTSYLEDNVAELGDTPAYRYLDFQDDH
                                                               *.  .    .  *  : ::  . 

Mb1548|M.bovis_AF2122/97            DGVEETLTWSQLYRRTLNLAAQLREHGSTGDRALILAPQILDYVVSFIAS
Rv1521|M.tuberculosis_H37Rv         DGVEETLTWSQLYRRTLNLAAQLREHGSTGDRALILAPQSLDYVVSFIAS
MUL_2008|M.ulcerans_Agy99           DGAAETLTWSQLYRRTLNVARELSSCGSVGDRAVILAPQGLEYVVAFLGA
MMAR_1180|M.marinum_M               AGIAETLTWSQLHRRTCNVARELKACGATGDRAVVLAPQGLDYIVAFLGA
MSMEG_4731|M.smegmatis_MC2_155      EGVAHTLTWSQLNRRVQSLAYEMQARSAVGDRAVILAPQGLDYVVAFLAS
MAB_0935c|M.abscessus_ATCC_199      TGVAESLTWSQLSRRTFNVARELGQHASPGDRALILAPQSLEYILAFLGS
Mvan_0272|M.vanbaalenii_PYR-1       AGVRQTLTWSQLSIRTLNLAREIRRHGAVGDRALILAPQGLEYILAFLGS
Mflv_0402|M.gilvum_PYR-GCK          AGVAETVTWSQLSRRTANVARVLARHGSAGDRAVILAPQGLEYILAFLGS
MLBr_01234|M.leprae_Br4923          AGVRKTLTWAQLYQRTLNVAHELRRHGSIRDRAVILAPQGLDYIIAFLGA
MAV_1328|M.avium_104                AGVAETLTWAQLYQRTSNLAREVARHGDTGDRAVILAPQGLSYIVAFLAA
TH_3603|M.thermoresistible__bu      RGRVVELTWREFGVRLHAIGARLQQVTKPGDRVAIVAPQGVDYVVGFFAA
                                     *    :** ::  *   :.  :       **. ::*** :.*::.*:.:

Mb1548|M.bovis_AF2122/97            LQAGIVAVPLSIPQGGAHDERTVSVFADTAPAIVLTASSVVDNVVEYVQP
Rv1521|M.tuberculosis_H37Rv         LQAGIVAVPLSIPQGGAHDERTVSVFADTAPAIVLTASSVVDNVVEYVQP
MUL_2008|M.ulcerans_Agy99           LQAGRIAVPLSVPQGGASDERATSVLRDASPVAILTASPVIDDVTQHVSA
MMAR_1180|M.marinum_M               LQAGQIAVPLSAPLGGASDERVGSVLRDALPSAILTTSPIAGDVAECITL
MSMEG_4731|M.smegmatis_MC2_155      LQAGRIGVPLSVPFPGVHDDRVTAVLRDTAPSIVLTTSAVSSHIAEYLEP
MAB_0935c|M.abscessus_ATCC_199      MQAGLIAVPLPLPHRGSSLDRVSAVFDDTSPSVVLTTSAVASDVGDYVDQ
Mvan_0272|M.vanbaalenii_PYR-1       MQAGLVAVPLPLPHPGSGHDRVGAVLHDTEPSVVLTTSATANDVGDYVAS
Mflv_0402|M.gilvum_PYR-GCK          MQAGMIAVPLPLPHRGSNHDRVSAVFTDTTPAVVLTTSAVAGDVGAYVDE
MLBr_01234|M.leprae_Br4923          MQAGFIAVPLSVPQAGSHDERVGAVLADTSPSVVLTTSAVADAIAKYVDH
MAV_1328|M.avium_104                IQAGLIAVPLSVPQPGSHDERVSAVLADTGPAVVLTTAAAAATVTEYLRR
TH_3603|M.thermoresistible__bu      IHAGLIAVPLFAPELPGHAERLDAVLADALPSVVLTTTAAAEAAGVFLRK
                                    ::** :.***  *      :*  :*: *: *  :**::.        :  

Mb1548|M.bovis_AF2122/97            QPGQNAPAVIEVDRLDLDAR-PSSGSRSAAHGHPDILYLQYTSGSTRTPA
Rv1521|M.tuberculosis_H37Rv         QPGQNAPAVIEVDRLDLDAR-PSSGSRSAAHGHPDILYLQYTSGSTRTPA
MUL_2008|M.ulcerans_Agy99           QSAGPAPSIIELDRLDLDAA-AGSG--AGTENYPATAYLQYTSGSTREPA
MMAR_1180|M.marinum_M               TPGKRAPSVIEIDLLDPDS---GQGPAAESDSGSDIAYLQYTSGSTRTPA
MSMEG_4731|M.smegmatis_MC2_155      QAGQAAPWIAEIDTLDLDTR----RRPVKREQAPETAYLQYTSGSTRTPA
MAB_0935c|M.abscessus_ATCC_199      SRLEIAPKLIEIDTLRLD---VDAGPSLVPGDVPNIAYLQYSSGSTRTPT
Mvan_0272|M.vanbaalenii_PYR-1       SRLDAAPTIVEVDALDLD---AGGGLSLEPADLPSIAYLQYSSGSTRLPA
Mflv_0402|M.gilvum_PYR-GCK          ARMQIAPTIVTVDTLDLDGTPSDDEPAVAAGEAPDIAYLQYSSGSTRLPT
MLBr_01234|M.leprae_Br4923          SDTDTVPAILEVDSPNLD---VENKSNIRLTDAPSTAYLQYTSGSTRLPA
MAV_1328|M.avium_104                PDTGPAPAVVEIDSLDLD---EPNSASIRISGAPDIAYLQYTSGSTRLPA
TH_3603|M.thermoresistible__bu      LPRERRPRMIAVDAIPDS---VGATFKPAQLKSSDLAYLQYTSGSTRTPA
                                          * :  :*    .               .   ****:***** *:

Mb1548|M.bovis_AF2122/97            GVMVSNKNLFANFEQIMTSYYGVYGKVAPPGSTVVSWLPFYHDMGFVLGL
Rv1521|M.tuberculosis_H37Rv         GVMVSNKNLFANFEQIMTSYYGVYGKVAPPGSTVVSWLPFYHDMGFVLGL
MUL_2008|M.ulcerans_Agy99           GVMLSHQNLVTNFEQLMSGYFADTDGIAPPDSTLVSWLPFYHDMGLVLGV
MMAR_1180|M.marinum_M               GVVVSHRNLLANVEQGMSAYFGDHGRAAPPDTTVVSWLPFFHDMGLMFGI
MSMEG_4731|M.smegmatis_MC2_155      GVMVSHRNLTANFEQVVAGFFPDN--IAPSDTTSISWLPLYHDMGLMLGL
MAB_0935c|M.abscessus_ATCC_199      GVMLSHRNLQVNFEQLMRSFFVDTGCTIPSNATIVSWLPFYHDMGLVLGV
Mvan_0272|M.vanbaalenii_PYR-1       GVMLSHRNLTVNFEQLMRSFFAEK--PLPPDATLVSWLPFYHDMGLVLGV
Mflv_0402|M.gilvum_PYR-GCK          GVMISHRNLQSNYEQLMRSFFAVPHIRSTAELTIVSWLPFYHDMGLVLGV
MLBr_01234|M.leprae_Br4923          GVMVTHRNLMVNFQQLMADYFAPTNGVAPLDLTIVSWLPFYHDMGLVLGV
MAV_1328|M.avium_104                GVMVSHRNLQVNFQQLMAAFFPDVDGVAPRDTVCVSWLPFYHDMGLVQGV
TH_3603|M.thermoresistible__bu      GVEITHRSVCTNVLQMILSVGLDWN------IRSVSWLPLFHDMGLLMIM
                                    ** ::::.:  *  * :                 :****::****::  :

Mb1548|M.bovis_AF2122/97            ILPILAGIPAVLTSPIGFLQRPARWIQMLASN---TLAFTAAPNFAFDLA
Rv1521|M.tuberculosis_H37Rv         ILPILAGIPAVLTSPIGFLQRPARWIQMLASN---TLAFTAAPNFAFDLA
MUL_2008|M.ulcerans_Agy99           CAPILGGYQAVLTSPVSFLQRPARWLQMLATS---SHAFSAAPNFAFELA
MMAR_1180|M.marinum_M               IMPLLEGFHSVLTSPISFLQRPARWMQLLASN---CQVFSAAPNIAFELA
MSMEG_4731|M.smegmatis_MC2_155      CAPVLGGWHTVLISPFAFLAKPARWMQLLATH---PATVTAAPNFAFDLA
MAB_0935c|M.abscessus_ATCC_199      CAPILGGYRADLTSPLAFLESPSRWVRALATN---PHAWSSAPNFAFDLA
Mvan_0272|M.vanbaalenii_PYR-1       CAPILCGRRAELMSPVSFLEKPSRWMRALAEN---PHAWSSAPNFAFDLA
Mflv_0402|M.gilvum_PYR-GCK          CAPILGGHPAKLTSPVAFLEKPSRWVRALAEN---PQAFSAAPNFAFELA
MLBr_01234|M.leprae_Br4923          VAPILGGWRSELTSPISFLQRPARWIQAMATS---SHPFSAGPNFAFELA
MAV_1328|M.avium_104                IAPILGGYPADLTSPVAFLQRPARWIQAMSRA---DPVFSAAPNFAFELA
TH_3603|M.thermoresistible__bu      YPALFGGY-LTLMSPVSFVRRPYRWLKALAEESVHGPAFAAAPNFAFELA
                                      .:: *    * **..*:  * **:: ::         ::.**:**:**

Mb1548|M.bovis_AF2122/97            SRKTKDEDMEGLDLGGVHGILNGSERVQPVTLKRFIDRFAPFNLDPKAIR
Rv1521|M.tuberculosis_H37Rv         SRKTKDEDMEGLDLGGVHGILNGSERVQPVTLKRFIDRFAPFNLDPKAIR
MUL_2008|M.ulcerans_Agy99           AKKVSDDDMAGLDLGNVLTILSGSERVQPATLKRFADRFARFNLQEKVLR
MMAR_1180|M.marinum_M               ARKTSDDDLAGLDLGGVRNILSGAERVQPATLARFAQRFARFHLHPRALR
MSMEG_4731|M.smegmatis_MC2_155      ARKTSDADLTGMDLGDVRCVLSGSERVHEPTLRRFSDRFAAFNLHEQALR
MAB_0935c|M.abscessus_ATCC_199      ARKTTDADLAGLDLGGVLGIISGAERVEQATLQRFVDRFAHFNFRDSMMR
Mvan_0272|M.vanbaalenii_PYR-1       ARKTTDADLAGLDLGGVVGIISGAERVEPATLHRFVDRFAHFNFQDHMMR
Mflv_0402|M.gilvum_PYR-GCK          ARKTRDSDLAGLDLGGVLGIINGAERVNPATLERFADRFAHFNFRDNMLR
MLBr_01234|M.leprae_Br4923          ARRTSDADIAGLDLGACQGIISGSERIHPATLNRFSDRFARINFRDDMML
MAV_1328|M.avium_104                VRKTTDADLAGVNLGNIISIVSGAERIHPATLRRFCKRFAPYNFREHMMQ
TH_3603|M.thermoresistible__bu      AQRGRPPAGESLDLSNVAGLINGSEPVSIHSINKFTEAFAPYGLPATTVK
                                     ::       .::*.    ::.*:* :   :: :* . **   :    : 

Mb1548|M.bovis_AF2122/97            PSYGMAEATVYVATRKAGQPPKIVQFDPQKLPDGQAERT--ESDGGTPLV
Rv1521|M.tuberculosis_H37Rv         PSYGMAEATVYVATRKAGQPPKIVQFDPQKLPDGQAERT--ESDGGTPLV
MUL_2008|M.ulcerans_Agy99           PSYGLAEATVYVSTSRPGQPPELVEFDAESLSTGQAKQC--ESGAGTQLV
MMAR_1180|M.marinum_M               PSYGLAEATVFVATREWGQPPVTVYFDSDELTAGHAKRC--ATGTGTALI
MSMEG_4731|M.smegmatis_MC2_155      PSYGLAEATLFVATRETGHPPKVARFAAQELSDGRAVPC--DDENGTALV
MAB_0935c|M.abscessus_ATCC_199      PSYGLAEATVFVASGTWSETAPAAHFDVEELSAGRVRRC--AAGAGTALV
Mvan_0272|M.vanbaalenii_PYR-1       PSYGLAEATVFVASGVWSESSPAAHFDTEGLAAGRVQPC--AAGKGTALV
Mflv_0402|M.gilvum_PYR-GCK          PSYGLAEATVFVASGIYRESADEARFDSNELSAGRVARR--TTG-GTALV
MLBr_01234|M.leprae_Br4923          PSYGLAEGTVYAASRPKGSSPEVVYFEPAKLSEGTVKRC--EARTGAPLL
MAV_1328|M.avium_104                PSYGLAEATVYVASRAEAGAPEVVHFEPEKLSAGSAQRC--PAQTGSPLL
TH_3603|M.thermoresistible__bu      PSYGMAEATLFVSTIPPDAKATAVYLDREKLNAGYAVKVSPDADNAVPHV
                                    ****:**.*::.::      .  . :    *  * .         .   :

Mb1548|M.bovis_AF2122/97            SYG-IVDTQLVRIVDPDTGIERPAGTIGEIWVHGDNVAIGYWQKPEATER
Rv1521|M.tuberculosis_H37Rv         SYG-IVDTQLVRIVDPDTGIERPAGTIGEIWVHGDNVAIGYWQKPEATER
MUL_2008|M.ulcerans_Agy99           SYI-LPRSPIVRVVDPDTCTECPDGTVGEIWVCGDNVAIGYWNKPEESER
MMAR_1180|M.marinum_M               SYG-AAQSPTVRIVDPQTATECPAGVVGEIWVHGDNVAAGYWHRPQETER
MSMEG_4731|M.smegmatis_MC2_155      SYG-MPESPTVRIVDPQTRAECPTGIVGEIWVHGENVCAGYWEQSERTET
MAB_0935c|M.abscessus_ATCC_199      QYK-VPHSPVLRIIDSDTHRECPADVVGEIWVHGDNVASGYWRKSPEEQR
Mvan_0272|M.vanbaalenii_PYR-1       KYK-VPQSPLLRIVDGDTHRECPSDVIGEIWVHGENVAAGYWNKPSEDQS
Mflv_0402|M.gilvum_PYR-GCK          NYT-LPQAPTVRIVDVETNRECASDVVGEIWVHGENVAAGYWSRPADEQQ
MLBr_01234|M.leprae_Br4923          SYG-TPKSPIVRIVDSDTCIECPTGRVGEIWLHGDNVAEGYWHKPEETQR
MAV_1328|M.avium_104                SYG-APTSPTVRIVDPDTNTERADGTVGEIWVNGENVAQGYWRKPEETRR
TH_3603|M.thermoresistible__bu      SCGHVARSQWAVIVDPETEVELPEGRVGEIWLHGDNVGRGYWGRPRETEI
                                    .      :    ::* :*  * . . :****: *:**  *** :.   . 

Mb1548|M.bovis_AF2122/97            TFSATIVN------PSEGTPA-GPWLRTGDSGFLSEGELFIMGRIKDLLI
Rv1521|M.tuberculosis_H37Rv         TFSATIVN------PSEGTPA-GPWLRTGDSGFLSEGELFIMGRIKDLLI
MUL_2008|M.ulcerans_Agy99           TFGGKLAS------PSEGIPE-GPWLRTGDSGFITDGKMFIIGRIKDLLI
MMAR_1180|M.marinum_M               TFGATLVG------PSPGTPP-GPWLRTGDLGAFSEGELFIIGRIKDLLI
MSMEG_4731|M.smegmatis_MC2_155      TFGASIDS------PSAGTPT-GPWLRTGDLGFVSGGELFIVGRIKDVVI
MAB_0935c|M.abscessus_ATCC_199      CFGAQIAD------PSAGTPE-GPWLRTGDLGFVSEGELFIVGRIKDLLI
Mvan_0272|M.vanbaalenii_PYR-1       CFGATLVD------PAPGVPD-GPWLRTGDLGFIDGGELFIVGRIKDLLI
Mflv_0402|M.gilvum_PYR-GCK          CFGATLAD------PSPGTPA-GPWLRTGDLGFVHGGELFIVGRIKDLLI
MLBr_01234|M.leprae_Br4923          TFGGKLAN------PSPGTPE-GPWLRTGDLGFISEDELFIVGRMKDLLI
MAV_1328|M.avium_104                TFGGVLVN------PSPGTPR-QPWLRTGDLGFISAGELFIVGRMKDLLI
TH_3603|M.thermoresistible__bu      SFGNKLQSRLEVGSHATGVPEDALWFRTGDLGMYLDGELYITGRIKDMII
                                     *.  : .       : * *    *:**** *    .:::* **:**::*

Mb1548|M.bovis_AF2122/97            VYGRNHSPDDIEATIQTISP----GRCAAIAVS-EHGAEKLVAIIELKKK
Rv1521|M.tuberculosis_H37Rv         VYGRNHSPDDIEATIQTISP----GRCAAIAVS-EHGAEKLVAIIELKKK
MUL_2008|M.ulcerans_Agy99           VYGRNHSPDDIEATIQEITR----SRCAAISVPGDRSTEKLVAIIEYRRR
MMAR_1180|M.marinum_M               IYGRNHSPDDIEATIQEVTR----GRCVAIAVPDDGGVEKLVVIVEFKTR
MSMEG_4731|M.smegmatis_MC2_155      IRGRNHYPDDIEATVQEITR----ARAAAISVD-RDDAEHLVVIAEVREN
MAB_0935c|M.abscessus_ATCC_199      IRGRNYYPEDIEATVQEISR----GRVAAISVP-FDSTEKLVTIIELKK-
Mvan_0272|M.vanbaalenii_PYR-1       IRGRNHYPEDIEATVQEITR----GRVAAISIP-VNSTEKLVTVIELKK-
Mflv_0402|M.gilvum_PYR-GCK          IRGRNHYPEDIEATVQGITR----GRVAAISVP-ENSTEKLVTVIELKKS
MLBr_01234|M.leprae_Br4923          VYGRNHYPEDIESTVQEITG----GRVAAISVP-VDETEKLVTIIEVKKR
MAV_1328|M.avium_104                VYGRNHYPEDIESTVQAVTG----GRVAAISVP-ADETEKLVTIIELKRR
TH_3603|M.thermoresistible__bu      VDGRNHYPQDVEATVAAASKQVRTGYVAAFSVPDEDGRERLVIIAERAP-
                                    : ***: *:*:*:*:   :     .  .*:::      *:** : *    

Mb1548|M.bovis_AF2122/97            DESDDEAAERLGFVKREVTSAISKSHGLSVADLVLVSPGSIPITTSGKIR
Rv1521|M.tuberculosis_H37Rv         DESDDEAAERLGFVKREVTSAISKSHGLSVADLVLVSPGSIPITTSGKIR
MUL_2008|M.ulcerans_Agy99           GDSDQEAMDMLVAVKREVTSALSNSHGLSVADLVLVAPGSIPTTTSGKVR
MMAR_1180|M.marinum_M               ETSHEATMHRMGVVRRDVIAAISKTHGLNVADLVLVPPGSIPLTTSGKVR
MSMEG_4731|M.smegmatis_MC2_155      QNPDVSPAEYLADLEGEVVAAVSRSHGIIPADLVLVRRGAIPITTSGKVR
MAB_0935c|M.abscessus_ATCC_199      ----RSDT-DIEAIRSEITSAISNAHGVNVGDVVLVPPGSLPTTTSGKIR
Mvan_0272|M.vanbaalenii_PYR-1       ----PAHLGELSEVKSDVTAAISNAHGLNVEDLVLVPSGSIPTTTSGKIR
Mflv_0402|M.gilvum_PYR-GCK          AEPDADATRWLSEVKSDITSAISNAHGLNVEDLVLVPPGSIPTTTSGKVR
MLBr_01234|M.leprae_Br4923          GDSDAEAMQKLVAVKNNITAAISKSHGLNVADLVLVPPGSIPTTTSGKVR
MAV_1328|M.avium_104                GDSDEDARRKLDAVKNEVTAAISIAHGLNVADLVPVAPGSIPTTTSGKIR
TH_3603|M.thermoresistible__bu      ----GAGKADPEPIRDTIRAAVSRYHALPIHDIKLVAAGAIPRTTSGKLA
                                                 :.  : :*:*  *.:   *:  *  *::* *****: 

Mb1548|M.bovis_AF2122/97            RAQCVELYRQDEFTRLDA--------------------------------
Rv1521|M.tuberculosis_H37Rv         RAQCVELYRQDEFTRLDA--------------------------------
MUL_2008|M.ulcerans_Agy99           RAACVEQYRQQQFARLDV--------------------------------
MMAR_1180|M.marinum_M               RRECLQRYLHDEFTRLDGQLREPGPRVADAAAADADAGADSGLVQRLRLL
MSMEG_4731|M.smegmatis_MC2_155      RASCAEQYRDDTFARLVHA-------------------------------
MAB_0935c|M.abscessus_ATCC_199      RRSCVEQYLQHEFIRLDADSPVGVA-------------------------
Mvan_0272|M.vanbaalenii_PYR-1       RAACVEQYRQDQFVRLDA--------------------------------
Mflv_0402|M.gilvum_PYR-GCK          RSACVDHYRQDQFDRLDA--------------------------------
MLBr_01234|M.leprae_Br4923          RTACVEQYRRQQFSRLDG--------------------------------
MAV_1328|M.avium_104                RAACVERYLRGAFIRLDG--------------------------------
TH_3603|M.thermoresistible__bu      RRACRAEYLAGEYGPVAR--------------------------------
                                    *  *   *    :  :                                  

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               RHQQHDLLVGVVCAQAATVLDYPSPNDIDPEWAFQDLGFDSVKATELLDR
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LQTVTELTLPPTLAFDYPTPAALATHLGQLLSGSVAVAAPVQPRVSTDEP
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               VAVVGMACRFPGGVDSAAALWDLVAGGTEAVGEFPADRGWNLAELFDPDP
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               DAVGKTYARAGSFVADVAGFDAEFFGISAREAQTMDPQQRLLLEVCWEAL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               ETAQIDPAALLRSKTGVFVGAWSQQYGGGSEGAEGYGLTGLSTSVASGRV
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               AYALGLQGPAITIDTACSSSLVAAHLACQSLHTGESTLALAGGVTVMTTP
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               AVFTEFARQRGLAADGRCKAFSAAADGTGWGEGAAVLVLERLSDANRNGH
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               PVLAVIAGSAINQDGASNGLTAPSGPAQQRVITQAVANAGVGLDEVDAVE
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               AHGTGTTLGDPIEAGALIATYGAAHHPDHPLWLGSIKSNIGHTQAAAGVA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               GLIKMIAALNHDSLPPTLNVDRPSPHVDWSAGTVRVLTEPVPWPVTDHPR
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TAAVSSFGISGTNAHLILQQAPTPSSGSPEPAGRPQHGAELGLPMWPVSA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               RTPAGLAAQAERLHQHLLRHRDLDLTDVGYSLGCTRTHHPHRAVVTVPAA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               SPDPRAELLAALQALAAGDPHPQLVQHHLRSTSAGKTVFVFPGQGGQYPG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               MAAELYRRHQVFSRALDECDQALFGWTGWSVGAVVRGEPSAMALQRVDVV
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               QPVLFAVMVSLARTLISYGIEPDAVIGHSQGEIAAAYVAGVFTLEQAAKI
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               VALRSAALADLSGTGGMASVLLGADEVAARLQPYGDALTVAAVNGPTHTI
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               ISGDPPAIEAFVAAGEADGIQIRSITVDYASHCGQVEPARERLLGELAGL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TPAPGRIALYSTVHGVTSDQPLDTTTMTADYWYANLRQPVRFYDSIKVLL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               AAAEQVFVEISPHPVLAPAITDTLAASNGQRPGSVVIPTLHRERPDLDAL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TTTLARLQVHGRGPAWPVVYPHARPVPLPTYPFQHHRYWLTTGPGNDAAG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LGLDRVGHPLLGAITALADRDEVIATGRLALGVQGWLGAHRVGDVVVLPG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TAFVDMALAVGDYVGCPAVAELVLHAPLVLAEDTPTDIQIGVAGADGGAR
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               RAFNVHARTGTGHRGETGWVLHASGILAAEPAAAGQPPMAALPVTEFDVA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               DFYQRLADRGLHYGPPFCSVLGIGHEPADPDHIYAEVALPAGTDITGYGI
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               HPALLDAALHPMAAALGAGADSESAAVRLPFVLSGVTLHATAATRLQVWL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TRSSADTFTLYASDPAGAPVISIDTVVVRALPDLATLTPPTTATSSGRGL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               WELAWPPLSSAGAPGAAVVAEPPAWVVVAEDPDAVSAGLRNGVRRPDLDA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               VRPCPPVVIWSLSPPDLRGDDDAVVSSMHSLTRHALAAVAAWLARPDTAE
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TVLVVLTCRAVAINAYERAPNPAQAAVWALLHSAQSEHPGRIRLVDTDHA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               ASSTDTLLQLLGSCTGTGGEPQLALRAGVAHMPRLAPARALTPPPTPHWR
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LITSGSGDLADLTLAPTPAPAELGPGQIRVQIRAAGLNSDDVAVASAATS
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               HRDAGGEGQQDHQGLGVEAAGIVIDTAGDVDDLAPGDAVMGIFPNNAFAP
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TAATDHRAVVAIPPGWSCPQAASVPVAFVTAYSALIDIAALRAGQRVLIH
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               SGAGAVGRAAIRIAQHLGAEVFATADPAEQHILRGLGIPEDHIASSRARD
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               FGDTLAAATGGRGMDVVLNDLRGDLVDASLRLLAAPGCFVEIARRDIREA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TDVAQTHPGLRYVVYDISTATPERLQRTWAAVSELINAAVIEPPPVTAYG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LLRARQAFRDISEARPSGKVVLIAPAALDPAGTVLITGGTGMLGGLFAEH
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LLTHYGVRRLLLTSRRGPSGVGAAELAERLNGLGAQVTISACDCADPAQL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               AALIDSIPTEHPLTAVIHAAGVLDDAVTSQLTAQQLDTVLAAKADSAWHL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               HQLTANTELAAFVLFSSAAGVLGAPGQANYAAANAVLDALARERGPGATS
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               LAWGYWQPSSGMTGHLDARDQARLTRSGMVPITTSAGLALFDAALGVQHP
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               NLIPAPLSTRALAALARESSLPPIFSALISTRPQAAMADSRALGARLAGL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TPEQQHAMLTKLVLTATAAVLAHPDPAAMDPDQPFKDLGIDSLSALELRG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               ALSAQSGVDLPATLIFDHPSPASVAVHLADLLSVAAVPAAAAAQVGKRAA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               EPADDRLAYLDQAAFLGLRAGYGSLIQMIWIYDRAVDVEGLRRFHRNLGC
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               GLLGRRIERSPLPFARDRWVSAPVSQQIDFATTPRRRADVGAWADERARL
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               PIDPEWGPGWHLGVVGLDDGGTAVSLVASHTIADAIAFGQAVVNAAEGRT
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               QDLGYPAAGSRILRRALREDLRQTVNELPKIAHAFGGVVRRLRRDRQELQ
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               SSIKAAPPPPRMAGGDHSVEVPAVTAYIDLADWDACAKRLGAKSNSLVGG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               VACRLAARVGRVQGDGTVTLRIVVSLRTKDDTRGNALTAVDVAVDPAHAA
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               TDLREMHAKITRAILEGMEDLDNEFLAPLPLAAITPRWVARRLVGMAAGG
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MUL_2008|M.ulcerans_Agy99           --------------------------------------------------
MMAR_1180|M.marinum_M               PTLPVTCSNVGDVPPAANRPDGTDADFAYIRLVEPDIAKSVLEGTGGRML
MSMEG_4731|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
MAV_1328|M.avium_104                --------------------------------------------------
TH_3603|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1548|M.bovis_AF2122/97            -----------------------------------------------
Rv1521|M.tuberculosis_H37Rv         -----------------------------------------------
MUL_2008|M.ulcerans_Agy99           -----------------------------------------------
MMAR_1180|M.marinum_M               LASGRGRGKMCIGISAYLVGHSNTKDELREVVSRTFAEFGLNAEIDC
MSMEG_4731|M.smegmatis_MC2_155      -----------------------------------------------
MAB_0935c|M.abscessus_ATCC_199      -----------------------------------------------
Mvan_0272|M.vanbaalenii_PYR-1       -----------------------------------------------
Mflv_0402|M.gilvum_PYR-GCK          -----------------------------------------------
MLBr_01234|M.leprae_Br4923          -----------------------------------------------
MAV_1328|M.avium_104                -----------------------------------------------
TH_3603|M.thermoresistible__bu      -----------------------------------------------