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M. abscessus ATCC 19977 MAB_3579c (-)

annotation: putative acyl-CoA synthase/polyketide synthase
coordinates: 3625447 - 3627192
length: 581

QTTYDFTDYFSTVTEWVARQPDQIALGYLEEGAGELTERAWTYAELVSHATAVAARLREDLEPGDRTLLL
YPPGLPFVAAFLGCLAAGVVAVPAPLPDGRDKAQHRLAGIIADAGTRVVLTESSVAPLIAGWADALPTPI
ALIATDAIPVELGREFVPVRSAPSDTAFLQYTSGSTNAPKGVIVTHGNLVHNEQELGARIENDPSFSMLS
WLPQFHDMGLIGMLLWPLFYGGTSRFLSPVTFIKHPIQWIRAMSKYRATVGVAPNFAFDLVARRCTHEAL
EGVDLSCVRSLLNGSEPVQWASIERFTTLLAPFGLAEHAVTPVYGLAEATLFVTGDPHGTPVTTAVVDGE
ALAENRLVVANEGAPRSRVLVASGRIGGIEVSVVGADGAPLPDGEIGEIWLRGTSVAAGYWNLPELSAEI
FGATPIGGTGGWLRTGDLGTLVDGNLFITGRTKDVIIVNGRNLYAHDIEAAARAAAPALARGVGAAFAVG
TPERLVLVHEIRPENLGDASLDDVLAAVRTAIFAEFATPLSDLVLVAKGEVARTTSGKIRRTHMRASYEG
GRITAFADPRLASAGGDVVR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3579c--100% (581)putative acyl-CoA synthase/polyketide synthase
M. abscessus ATCC 19977MAB_1174c-7e-9940.28% (566) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_1915-1e-9437.72% (562) acyl-CoA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1960fadD311e-8436.63% (576) acyl-CoA synthetase
M. gilvum PYR-GCKMflv_2901-2e-9938.43% (575) acyl-CoA synthetase
M. tuberculosis H37RvRv1521fadD258e-8536.78% (571) acyl-CoA synthetase
M. leprae Br4923MLBr_01234-6e-8536.22% (566) acyl-CoA synthetase
M. marinum MMMAR_0468-2e-9240.77% (547) fatty-acid-CoA ligase
M. avium 104MAV_2777-3e-8636.10% (579) acyl-CoA synthetase
M. smegmatis MC2 155MSMEG_4301-4e-9639.18% (564) acyl-CoA synthetase
M. thermoresistible (build 8)TH_4458-1e-10139.54% (564) PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide
M. ulcerans Agy99MUL_1117-6e-9140.40% (547) fatty-acid-CoA ligase
M. vanbaalenii PYR-1Mvan_3604-2e-9638.86% (579) acyl-CoA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1960|M.bovis_AF2122/97            MNDGSRQELRVRSGLLQIEDCLDADGGIALPAGTTLISLIERNIKYVGDL
MAV_2777|M.avium_104                MDDALRRDDGVP-GLLRIEDCLDADGGVALPPGVNLISLIDRNIANVGDT
Mflv_2901|M.gilvum_PYR-GCK          -----------MSPELRLDDYLDHEGNIVIPPGTTLTSFLGRNAAEFGDT
Mvan_3604|M.vanbaalenii_PYR-1       -----------MSPILRLDDYLDREGNIAIPAGVTLTAFLARNVAELGEA
MSMEG_4301|M.smegmatis_MC2_155      ---------------MKIEDYLDADGNIAIPDGVTLTSYFDRNVAELADT
MAB_3579c|M.abscessus_ATCC_199      --------------------------MQTTYDFTDYFSTVTEWVARQPDQ
TH_4458|M.thermoresistible__bu      -----------------------------------LLSLLRQRSERYGDK
MMAR_0468|M.marinum_M               ----------------MNESIPGGRVAHLPPPHLNLVERLAWRARNQPDE
MUL_1117|M.ulcerans_Agy99           -------------------------MAHLPPPHLNLVERLAWRARNQPDE
Rv1521|M.tuberculosis_H37Rv         ----------------------------MSVVESSLPGVLRERASFQPND
MLBr_01234|M.leprae_Br4923          ------------------------------MQNSSVLSFLRERAGLQPDD
                                                                           .        : 

Mb1960|M.bovis_AF2122/97            VAYRYLDHARSAAGCALEVTWTQFGMRLAAIGAHVQRFAGPGDRVAILAP
MAV_2777|M.avium_104                VAYRYLDYSGSDDGTAHEVTWSQFGVRLEAIGARIQQVASRGERVAVLAP
Mflv_2901|M.gilvum_PYR-GCK          PAYRYLDFEHD---RTIELTWAQLRTRLDAVGARLQQVTRPGDRVAILTP
Mvan_3604|M.vanbaalenii_PYR-1       PAYRYLDFDHD---CTVELSWTQLGARLSAVGARLQQVTQRGDRVAVLTP
MSMEG_4301|M.smegmatis_MC2_155      PAYRYLDFEHDG--RVVELTWKELDTRVRAVGARLQQVTKLGDRVAILCP
MAB_3579c|M.abscessus_ATCC_199      IALGYLEEGAG-ELTERAWTYAELVSHATAVAARLREDLEPGDRTLLLYP
TH_4458|M.thermoresistible__bu      IAFDYCTG----EQEHSRLTYQELDIRARAIAAHLQDQGVAGERVLVLCP
MMAR_0468|M.marinum_M               LAMVELRG--M-RGETDKATYARLDARARAIAFQLKSLGNQGDRVLLVMG
MUL_1117|M.ulcerans_Agy99           LAMVELRG--M-CGETDKATYARLDARARAIAFQLKSLGNQGDRVLLVMG
Rv1521|M.tuberculosis_H37Rv         KALTFIDYERSWDGVEETLTWSQLYRRTLNLAAQLREHGSTGDRALILAP
MLBr_01234|M.leprae_Br4923          EAFSFTDYEQDWAGVRKTLTWAQLYQRTLNVAHELRRHGSIRDRAVILAP
                                     *                 :: .:  :   :. .::      :*. ::  

Mb1960|M.bovis_AF2122/97            QGIDYVCGFYAAIKAGTVAVPLFAP-ELPGHAERLDTALRDSEPAVILTT
MAV_2777|M.avium_104                QGIDYVAGFYAAVKAGTIAVPLFAP-ELPGHAERLDTALRDSQPSVLLTT
Mflv_2901|M.gilvum_PYR-GCK          QGVEYVIGFFAAIEAGAIAVPLFAP-ELPGHSERLHAVLADAQPSVVLTT
Mvan_3604|M.vanbaalenii_PYR-1       QGVEYVVGFFAAILAGAIAVPLFAP-ELPGHTDRLDAVLKDAEPSVVLTT
MSMEG_4301|M.smegmatis_MC2_155      QGVDYVVSFFAAIQAGAIAVPLFSP-ELPGHAERLEAVLADATPSVVLTT
MAB_3579c|M.abscessus_ATCC_199      PGLPFVAAFLGCLAAGVVAVPAPLPDGRDKAQHRLAGIIADAGTRVVLTE
TH_4458|M.thermoresistible__bu      SGLDFITAMFGCFYVGAVAVPVHPP-VHNRLLSRVASIVADVRATSVLTT
MMAR_0468|M.marinum_M               NCLDYVVGFLACAYARRVAVNLPVP-RRAKHLDRLAHVVADCGAEVLLTS
MUL_1117|M.ulcerans_Agy99           HCLDYVVGFLACAYARRVAVNLPVP-RRAKHLDRLAHVVADCGAEVLLTS
Rv1521|M.tuberculosis_H37Rv         QSLDYVVSFIASLQAGIVAVPLSIP-QGGAHDERTVSVFADTAPAIVLTA
MLBr_01234|M.leprae_Br4923          QGLDYIIAFLGAMQAGFIAVPLSVP-QAGSHDERVGAVLADTSPSVVLTT
                                      : :: .: ..  .  :**    *        *    . *  .  :** 

Mb1960|M.bovis_AF2122/97            AAAKNAVEGFLNNVPRLRKPTVLVID--QIPDREGELFVPVELDIDAVSH
MAV_2777|M.avium_104                TVARDAVEQFLAGHPHLHRPRVIAID--EIPDSAAESFAPTELGMDDVSH
Mflv_2901|M.gilvum_PYR-GCK          TATAEPVREFLRALPHNRRPRLIAVD--AVPDSVGVGFQRAPLQTDDVAY
Mvan_3604|M.vanbaalenii_PYR-1       TAAAQPVRDFIRKLPRDRRPRIIAVD--AVPDSVGTDFTPAPLQTDDIAY
MSMEG_4301|M.smegmatis_MC2_155      TAAAEAVGAFVRKLPHAGRPRMIAVD--AVPAAVGATFTPAQLHTDGIAY
MAB_3579c|M.abscessus_ATCC_199      SSVAPLIAGWADALP--TPIALIATD--AIPVELGREFVPVRSAPSDTAF
TH_4458|M.thermoresistible__bu      AATRADLKEILDGLHDGDPLRWLAVD--TIEADDETSWTPTTVDTDSVAF
MMAR_0468|M.marinum_M               GPEAKELTVSVAADLRLDFLTVLRLD--WLLAIPDEDWQPVAPASKDVCL
MUL_1117|M.ulcerans_Agy99           GPEAKELTASVAADLRLDFLTVLRLD--WLLAIPDEDWQPVAPASKDVCL
Rv1521|M.tuberculosis_H37Rv         SSVVDNVVEYVQPQPGQNAPAVIEVDRLDLDARPSSGSRSAAHGHPDILY
MLBr_01234|M.leprae_Br4923          SAVADAIAKYVDHSDTDTVPAILEVDSPNLDVENKSNIR--LTDAPSTAY
                                          :               :  *   :                    

Mb1960|M.bovis_AF2122/97            LQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDL-----LNRNTHGVSWL
MAV_2777|M.avium_104                LQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDL-----LDRNTHGVSWL
Mflv_2901|M.gilvum_PYR-GCK          LQYTSGSTRAPAGVKITHRSACTNVVQMVLSVG------LDPDINSVSWL
Mvan_3604|M.vanbaalenii_PYR-1       LQYTSGSTRAPAGVEITHRSACTNIVQMVLSVG------LDPDIQSVSWL
MSMEG_4301|M.smegmatis_MC2_155      LQYTSGSTRTPAGVEITHRGVCTNVLQMIISVG------LDWNIRSVSWL
MAB_3579c|M.abscessus_ATCC_199      LQYTSGSTNAPKGVIVTHGNLVHNEQELGARIE------NDPSFSMLSWL
TH_4458|M.thermoresistible__bu      VQYTSGSTSTPKGVVLTHHNLLANLESISRDAG------QGDEARVVSWL
MMAR_0468|M.marinum_M               LQYTSGSTSAPRGVVVTHDNLMFNCAQIQYGFG------LTAEDRALSWL
MUL_1117|M.ulcerans_Agy99           LQYTSDSTSAPRGVVVTHDNLMFNCAQIQYGFG------LTAEDRALSWL
Rv1521|M.tuberculosis_H37Rv         LQYTSGSTRTPAGVMVSNKNLFANFEQIMTSYYGVYGKVAPPGSTVVSWL
MLBr_01234|M.leprae_Br4923          LQYTSGSTRLPAGVMVTHRNLMVNFQQLMADYFAPTNGVAPLDLTIVSWL
                                    :****.**  * ** :::     *  .:                  :***

Mb1960|M.bovis_AF2122/97            PLYHDMGLS-MIGFPAVYGGHSTLMSPTAFVRRPLRWIQALSEGSRTGRV
MAV_2777|M.avium_104                PLYHDMGLS-MIGFPAVYGGHSTLMSPAAFVRRPQRWIKALSDGSRHGNV
Mflv_2901|M.gilvum_PYR-GCK          PLFHDMGLL-MIMFPALAGGYLTLMSPVAFVRRPYRWIKELGADDRP--M
Mvan_3604|M.vanbaalenii_PYR-1       PLFHDMGLL-MIMFPAVAGGHLTLMSPVAFVRRPYRWIKELGATDAP--T
MSMEG_4301|M.smegmatis_MC2_155      PLFHDMGLL-MIMFPALCGGHITLMSPVSFVRRPYRWIKELGASDVP--T
MAB_3579c|M.abscessus_ATCC_199      PQFHDMGLIGMLLWPLFYGGTSRFLSPVTFIKHPIQWIRAMSKYRAT---
TH_4458|M.thermoresistible__bu      PLHHDMGLIGGIFGVVHFGGTAYLMPPSSFIQRPMSWLEAISWHGAN---
MMAR_0468|M.marinum_M               PLYHDMGLILGVLTPIFAGFPVVLADPLSFVKRPDLWLRAISDYRIT---
MUL_1117|M.ulcerans_Agy99           PLYHDMGLILGVLTPIFAGFPVVLADPLSFVKRPDLWLRAISDYRIT---
Rv1521|M.tuberculosis_H37Rv         PFYHDMGFVLGLILPILAGIPAVLTSPIGFLQRPARWIQMLASNTLA---
MLBr_01234|M.leprae_Br4923          PFYHDMGLVLGVVAPILGGWRSELTSPISFLQRPARWIQAMATSSHP---
                                    * .****:   :      *    :  *  *:::*  *:. :.        

Mb1960|M.bovis_AF2122/97            VTAAPNFAYEWAAQRGLPAQGDDVDLSNVV-LIIGSEPVSIDAVTTFNKA
MAV_2777|M.avium_104                VTAAPNFAYEWAAQRGLPGGGEDIDLRNVV-MIIGSEPVSMDAIRTFNKA
Mflv_2901|M.gilvum_PYR-GCK          FAAAPNFAFALAAQRGLPPEGEELDLSNVAGLINGSEPISVAAVEAFNAA
Mvan_3604|M.vanbaalenii_PYR-1       FAAAPNFAFELAAERGLPPAGDTLDLSNVAGLINGSEPVNISSVEKFNAA
MSMEG_4301|M.smegmatis_MC2_155      FAAAPNFAYELAAHRGLPPAGDELDLSNVAGLINGSEPVSMASINVFNEA
MAB_3579c|M.abscessus_ATCC_199      VGVAPNFAFDLVARRCTHEALEGVDLSCVRSLLNGSEPVQWASIERFTTL
TH_4458|M.thermoresistible__bu      ISVGPNFGYQLCVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRFTEA
MMAR_0468|M.marinum_M               FTGGPNFAYDLCADAASYADLSGIDLSCWNVALNGAEPIRATTLERFNAA
MUL_1117|M.ulcerans_Agy99           FTGGPNFAYDLCADAASYTDLSGIDLSCWNVALNGAEPIRATTLERFNAA
Rv1521|M.tuberculosis_H37Rv         FTAAPNFAFDLASRKTKDEDMEGLDLGGVHGILNGSERVQPVTLKRFIDR
MLBr_01234|M.leprae_Br4923          FSAGPNFAFELAARRTSDADIAGLDLGACQGIISGSERIHPATLNRFSDR
                                    .  .***.:              :**        *:* :   ::  *   

Mb1960|M.bovis_AF2122/97            FAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATR
MAV_2777|M.avium_104                FAPYGLPRTAFKPSYGIAEATLFVATIAPRAEATAVYFDRRQLGAGHAVR
Mflv_2901|M.gilvum_PYR-GCK          FAPYGLKQTVIKPSYGMAEATLFVSTTPPDSALKAVYVDRKQLTAGRAVI
Mvan_3604|M.vanbaalenii_PYR-1       FAPYGLAPTVVKPSYGMAEATLFVSTTAPDARPEATYLDREKLTVGHAVR
MSMEG_4301|M.smegmatis_MC2_155      FAPYGLPPTAVKPSYGMAEATLFVSTIGPAAHPSAVYLDREELGAGRAVE
MAB_3579c|M.abscessus_ATCC_199      LAPFGLAEHAVTPVYGLAEATLFVTGDPHGTPVTTAVVDGEALAENRLVV
TH_4458|M.thermoresistible__bu      FAPAGFRADAFHPVYGLAEATLFVSGRPENVLPTVRSLDNAALREHRVVP
MMAR_0468|M.marinum_M               LAPLGWAPTYMQPSYGLAENTLAVSTKIPATEPTVVEIDVAALRQSQVCA
MUL_1117|M.ulcerans_Agy99           LAPLGWAPTCMQPSYGLAENTLAVSTKIPATEPTVVEIYVAALRQSQVCA
Rv1521|M.tuberculosis_H37Rv         FAPFNLDPKAIRPSYGMAEATVYVATRKAGQPPKIVQFDPQKLPDGQAER
MLBr_01234|M.leprae_Br4923          FARINFRDDMMLPSYGLAEGTVYAASRPKGSSPEVVYFEPAKLSEGTVKR
                                    :*  .     . * **:** *: .:            .    *       

Mb1960|M.bovis_AF2122/97            VAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQG
MAV_2777|M.avium_104                VPANAPDAVAAVSCGQVARSARAGIVA------DGAELPDGQVGEIWLHG
Mflv_2901|M.gilvum_PYR-GCK          VDSDHPDATVQVSCGNVARSQWAVIVDP--ATDC--ELPDGCVGEIWLHG
Mvan_3604|M.vanbaalenii_PYR-1       VDPGHPDAVAQVSCGTVSRSQWAAIVDP--GTET--EQPDGRVGEIWLHG
MSMEG_4301|M.smegmatis_MC2_155      VPEDDPRAIAQVSCGKIARSQWAVIVDP--NSDTGAELPDGHVGEIWLYG
MAB_3579c|M.abscessus_ATCC_199      ANEGAPRSRVLVASGRIG-GIEVSVVG-----ADGAPLPDGEIGEIWLRG
TH_4458|M.thermoresistible__bu      AAADDANAAAVVGCGPAAYGEEIVIVDP----ATRREFPPDVVGEIWVAG
MMAR_0468|M.marinum_M               PRGDSP-SRRLVSSGRILAGTMVKIVDP----ETGHPVGPDRVGEIWLTG
MUL_1117|M.ulcerans_Agy99           PRGDSP-SRRLVSSGRILAGTMVKIVDP----ETGHPVGPDRVGEIWLTG
Rv1521|M.tuberculosis_H37Rv         TESDGGTPLVSYG---IVDTQLVRIVDP----DTGIERPAGTIGEIWVHG
MLBr_01234|M.leprae_Br4923          CEARTGAPLLSYG---TPKSPIVRIVDS----DTCIECPTGRVGEIWLHG
                                           .    .           :*              . :**:*: *

Mb1960|M.bovis_AF2122/97            DNVARGYWGRPEETRMTFGARLQSPLAEGSHADGSAIDDTWLRTGDLGVY
MAV_2777|M.avium_104                NNIGRGYWGMPEETRRVFGATLRSRLPDGSHAAGADPDGSWLRTGDLGVY
Mflv_2901|M.gilvum_PYR-GCK          DNIGNGYWERPEETELTFRNKLQSRLARGSHAERSADSALWLRTGDLGVY
Mvan_3604|M.vanbaalenii_PYR-1       DNIGRGYWGRPKETELTFQNKLQARLPAGSHAANCPENALWLRTGDLGVY
MSMEG_4301|M.smegmatis_MC2_155      DNVGKGYWGRPHETEVSFHNKLQSRLPQGSHAAGAPDGAAWFRTGDLGMY
MAB_3579c|M.abscessus_ATCC_199      TSVAAGYWNLPELSAEIFGATPIG------------GTGGWLRTGDLGTL
TH_4458|M.thermoresistible__bu      ENVAQGYLGKPSESAETFAAHLADS-----------GRGPFLRTGDYGFL
MMAR_0468|M.marinum_M               RSVAKGYWGRDIQTEEVFAARLPG------------DPARYLRTGDLGFC
MUL_1117|M.ulcerans_Agy99           RSVAKGYWGRDIQTEEVFAARLPG------------DPARYLRTGDLGFC
Rv1521|M.tuberculosis_H37Rv         DNVAIGYWQKPEATERTFSATIVNP-------SEGTPAGPWLRTGDSGFL
MLBr_01234|M.leprae_Br4923          DNVAEGYWHKPEETQRTFGGKLANP-------SPGTPEGPWLRTGDLGFI
                                     .:. **      :   *                      ::**** *  

Mb1960|M.bovis_AF2122/97            LDGELYITGRIADLLTIDGRNHYPQDIEATAAEASPMVRRGYITAFTVPA
MAV_2777|M.avium_104                LDGELYVTGRIADLVRIDGRNHYPQDIEATVAEASPMVRRGYVTAFSVPA
Mflv_2901|M.gilvum_PYR-GCK          LDGELYITGRIKDLIIVDGRNHYPQDIEATAAAASPSVRAGFVAAFSVPG
Mvan_3604|M.vanbaalenii_PYR-1       LDGQLYITGRIKDLVIVDGRNHYPQDIEATAGEASTSVRSGFVAAFSVPG
MSMEG_4301|M.smegmatis_MC2_155      LGGELYITGRIKDMVIVDGRNHYPQDLEATVAEASSQVRAGYIAAFSVPS
MAB_3579c|M.abscessus_ATCC_199      VDGNLFITGRTKDVIIVNGRNLYAHDIEAAARAAAPALARGVGAAFAVG-
TH_4458|M.thermoresistible__bu      LDGELFVTGRLKDLIIIRGRNYHPNDIEATVQEVHPALMSGRGAAFAVSP
MMAR_0468|M.marinum_M               RDDELFVVGRLKDLVIVHGANHYPQDLEETAEGAHPAVRSHFVAVFAEER
MUL_1117|M.ulcerans_Agy99           RDDELFVVGRLKDLVIVHGANHYPQDLEETAEGAHPAVRSHFVAVFAEER
Rv1521|M.tuberculosis_H37Rv         SEGELFIMGRIKDLLIVYGRNHSPDDIEATIQTIS----PGRCAAIAVSE
MLBr_01234|M.leprae_Br4923          SEDELFIVGRMKDLLIVYGRNHYPEDIESTVQEIT----GGRVAAISVPV
                                      .:*:: **  *:: : * *  ..*:* :             :.::   

Mb1960|M.bovis_AF2122/97            SDGDDRNQRLVIIAERAAG-TSRSDPRP----ALDAIRAAVCNRHGLSVA
MAV_2777|M.avium_104                VD-DPEAGRLVVVAERAAG-TSRQDPRP----AIEAIRAAVAQRHELAVA
Mflv_2901|M.gilvum_PYR-GCK          EG----REEVVIVAERAPG-AGRAEAAP----IQEAIRAEVSRKHAIPVR
Mvan_3604|M.vanbaalenii_PYR-1       DG----REEAVIVAERAPG-AGRAEAAP----IQESIRAAVSRRHALPVK
MSMEG_4301|M.smegmatis_MC2_155      EH----GERLVIVAERAPG-AGRADPAP----IVDAIRAAISKRHAVAVH
MAB_3579c|M.abscessus_ATCC_199      -----TPERLVLVHEIRPENLGDASLDD----VLAAVRTAIFAEFATPLS
TH_4458|M.thermoresistible__bu      DP--SGTEQLVIVQEVDRGRLGEVDTDE----LIAAIRTAVTSQHDIGVH
MMAR_0468|M.marinum_M               E----DREALIVVAEIRREAERGLDPRD----VGQRIARAITREHEVSVD
MUL_1117|M.ulcerans_Agy99           E----DREALIVVAEIRREAERGLDPRD----VGQRIARAITREHEVSVD
Rv1521|M.tuberculosis_H37Rv         HG----AEKLVAIIELKKKDESDDEAAERLGFVKREVTSAISKSHGLSVA
MLBr_01234|M.leprae_Br4923          DE----TEKLVTIIEVKKRGDSDAEAMQKLVAVKNNITAAISKSHGLNVA
                                              : : *         .           :   :   .   : 

Mb1960|M.bovis_AF2122/97            DLSFLPAGAIPRTTSGKLARQACRAQYLSGRLGVH---------------
MAV_2777|M.avium_104                DVRLLPAGAIPRTTSGKLARRACRAQYLDGSLGTR---------------
Mflv_2901|M.gilvum_PYR-GCK          DVKLVRSGVIPRTTSGKLARRSCRASYLDGTL------------------
Mvan_3604|M.vanbaalenii_PYR-1       DVKLVAAGVIPRTTSGKLARQACRAAYLNGEL------------------
MSMEG_4301|M.smegmatis_MC2_155      DIKLVAAGSIPRTTSGKLARRACQAQYLAELQTS----------------
MAB_3579c|M.abscessus_ATCC_199      DLVLVAKGEVARTTSGKIRRTHMRASYEGGRITAFADPRLAS--------
TH_4458|M.thermoresistible__bu      TVVLVDPLRIPTTSSGKIRRRTCRQRFLDGELDAFAEWRLATPRPAQPVP
MMAR_0468|M.marinum_M               AVFLARCGEVPKTTSGKIQRSLCRELLRQGGLALHGALEK----------
MUL_1117|M.ulcerans_Agy99           AVFLARCGEVPKTTSGKIQRSLCRELLRQGGLALHGALEK----------
Rv1521|M.tuberculosis_H37Rv         DLVLVSPGSIPITTSGKIRRAQCVELYRQDEFTRLDA-------------
MLBr_01234|M.leprae_Br4923          DLVLVPPGSIPTTTSGKVRRTACVEQYRRQQFSRLDG-------------
                                     : :     :. *:***: *                              

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      -----------------AGGDVVR--------------------------
TH_4458|M.thermoresistible__bu      AADEQADEQAGAGPGAGPGADEIRAWFVAQLAGELGLSPDDIDTGQPFAY
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      YGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPTIDLAAEHLAGLTHTATS
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      TAADAGVSTGAGRRPEHGPAPDRADEPIAIIGIGCRFPGADGPAAYWRLL
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      REGRDAITATPPERWDTDSVGDGTRWGGFLERIDGFDAGFFGISPREAVR
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      IDPQQRLLLEVAWEALEDAGLVPDRLAGSRTGVFTGVSTYDYLHLQLSHP
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      ELIDAYSGTGTASSIAANRLSYVFDFRGPSLTLDSACSSSLVAVHQACRS
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      LRDGECDLALAGGVNIMLSAGIGLNFTRAGVMATDGRCKTFDARADGWVR
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GEGAGIVVLKPLREALADEDPIYAVIRGSAVNQDGRTNGLMAPSRTAQEV
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      VLTDAYRRAGVSPGVVQYVEAQGIGTPVGDAIEVGALGTVLAEDRPPDSP
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      CLIGSVKTNIGHLEAAAGIAGLIKVALALRHRMIPPTLNFTEPNPTIEFD
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      KLPVRVAQTLTPWPDDSGRAVAGVSAFGFGGTNAHVVLAEAPQVRAAATA
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      DDHADGFVEILPLSARSQAALDALAERYESALTGGVPPADLCHTAGARRA
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      HHDHRLAVVGASRAELIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFS
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      DEGSQWRGMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADPSHS
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      RMDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAGVL
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GLDDAAALLCGRTRLSRLASTGAVREGLDGLLANLRPDDPRIPLYSTVTG
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      DAVTGRGFGAAHWMENLHSPVRFSAAVRRLLGRGHDAFLEISAHPMLLSA
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      VQEDAADLGRSCTTLVSMRRGECGRDVLMTSLAALYASGHAVDWARVHPH
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GSHCTAAPTYPWQRQRFWLDIDRCDTGDGAGTGGTAERTVVPAPLPAPSA
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      SAAPTVDEVLLCADQRERRELLESYLRDRVAAELGVLPPLLDVAAPLSTL
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      GIDSLTAAELRARVERDLGIVIPVAQLLNGPSVSDLAEWISTTMVGFGST
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            --------------------------------------------------
MAV_2777|M.avium_104                --------------------------------------------------
Mflv_2901|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3604|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4301|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3579c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4458|M.thermoresistible__bu      TPEPESAGVPGRSRPPDGAVASGSGDGGRWIELLNQMPEVSDDTVDELLR
MMAR_0468|M.marinum_M               --------------------------------------------------
MUL_1117|M.ulcerans_Agy99           --------------------------------------------------
Rv1521|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01234|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1960|M.bovis_AF2122/97            ---------------
MAV_2777|M.avium_104                ---------------
Mflv_2901|M.gilvum_PYR-GCK          ---------------
Mvan_3604|M.vanbaalenii_PYR-1       ---------------
MSMEG_4301|M.smegmatis_MC2_155      ---------------
MAB_3579c|M.abscessus_ATCC_199      ---------------
TH_4458|M.thermoresistible__bu      QLLAAGENHDDTQLH
MMAR_0468|M.marinum_M               ---------------
MUL_1117|M.ulcerans_Agy99           ---------------
Rv1521|M.tuberculosis_H37Rv         ---------------
MLBr_01234|M.leprae_Br4923          ---------------