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TDDQTRRIYRDAGITVEKLGEHIGARVNGIELRGDLSADRVEAIRLALAINKVLVFTEQHHLDDAGQYAF ARLLGEPTLPHPTVRSHGTELLNLEGAANGWHTDVTFVDRIPKASVLRPVTLPSYGGATTWASTVAAYEQ LPKPLRSLVDDLWATHTNLYDYASSGASGGVSAERRAAYYTEFTSSRYETVHPVVRVHPETGERSLLLGQ FVKSFQDLPSAEFASLFQLLQARITKLENTFRWNWRLGDVAIWDNRATQHYGIADFGEQQRELHRVTLAG DVPVDVHGRRSQILLGDASHYSGIETPQRLELFAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4209c | - | - | 100% (316) | putative dioxygenase |
| M. abscessus ATCC 19977 | MAB_0086 | - | 6e-95 | 55.08% (305) | putative taurine dioxygenase |
| M. abscessus ATCC 19977 | MAB_3621c | - | 1e-28 | 32.19% (292) | taurine dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 2e-81 | 53.72% (296) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_3107 | - | 1e-96 | 57.86% (299) | taurine dioxygenase |
| M. tuberculosis H37Rv | Rv3406 | - | 2e-81 | 53.72% (296) | dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1141 | tauD | 1e-84 | 55.02% (289) | taurine catabolism dioxygenase, TauD |
| M. avium 104 | MAV_4353 | - | 6e-83 | 54.14% (290) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. smegmatis MC2 155 | MSMEG_3870 | - | 1e-103 | 61.33% (300) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. thermoresistible (build 8) | TH_0024 | - | 3e-17 | 29.07% (289) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 9e-85 | 55.02% (289) | taurine catabolism dioxygenase, TauD |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 2e-17 | 29.27% (287) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3107|M.gilvum_PYR-GCK -----------MSSPDVVKLGAAIGARIDGVDLA-RGIDAGTAAQINAAL
MSMEG_3870|M.smegmatis_MC2_155 ------------MQVTVTKLGAHIGARIDGVRVG-GDLSPATVSAINAAL
MAB_4209c|M.abscessus_ATCC_199 MTDDQTRRIYRDAGITVEKLGEHIGARVNGIELR-GDLSADRVEAIRLAL
Mb3440|M.bovis_AF2122/97 ----------MTDLITVKKLGSRIGAQIDGVRLG-GDLDPAAVNEIRAAL
Rv3406|M.tuberculosis_H37Rv ----------MTDLITVKKLGSRIGAQIDGVRLG-GDLDPAAVNEIRAAL
MMAR_1141|M.marinum_M ----------MTDLITVKKLGSRIGAQVDGVSLG-ADLDAAAVDQIRAAL
MUL_0904|M.ulcerans_Agy99 ----------MTDLITVKKLGSRIGAQVDGVSLG-ADLDAAAVDQIRAAL
MAV_4353|M.avium_104 ----------MTGQITVTKLGSRIGARVDGVRLG-GDLDDATVEQIRRAL
TH_0024|M.thermoresistible__bu -----------MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDAL
Mvan_4182|M.vanbaalenii_PYR-1 -----------MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDAL
: :* :**.: * . : **
Mflv_3107|M.gilvum_PYR-GCK LEHKVIFFRGQHDLDDDGQLEFARALGTPT----TAHPTVTSRGA----K
MSMEG_3870|M.smegmatis_MC2_155 LEHKVIFFSGQDHLDDAGQLEFAELLGTPT----VAHPTLAEGAE----Q
MAB_4209c|M.abscessus_ATCC_199 AINKVLVFTEQHHLDDAGQYAFARLLGEPT----LPHPTVRSHGT----E
Mb3440|M.bovis_AF2122/97 LAHKVVFFRGQHQLDDAEQLAFAGLLGTP-----IGHPAAIALAD-DAPI
Rv3406|M.tuberculosis_H37Rv LAHKVVFFRGQHQLDDAEQLAFAGLLGTP-----IGHPAAIALAD-DAPI
MMAR_1141|M.marinum_M LEHKVIFFRNQHHLDDQQQLQFAGLLGTP-----IGHPAAAAALP-DAPI
MUL_0904|M.ulcerans_Agy99 LEHKVIFFRNQHHLDDQQQLQFAGLLGTP-----IGHPAAAAALP-DAPI
MAV_4353|M.avium_104 LTHKVIFFRHQHHLDDSRQLEFARLLGTP-----IGHPAASALAAKHLPV
TH_0024|M.thermoresistible__bu EEHGVLVFRG-LRIDPQTQVKFCRHLGEVDHSSDGHHPVAGIYPVTLDKS
Mvan_4182|M.vanbaalenii_PYR-1 EDNGVLVFPG-LHLEPEVQVEFCRRLGEIDFSSDGHHRVAGIYPVTLDKS
: *:.* :: * *. ** * .
Mflv_3107|M.gilvum_PYR-GCK VLPIDSRYDKADSWHTD---VTFVDRIPKASLLRAVTLPAYGGTTAWAST
MSMEG_3870|M.smegmatis_MC2_155 LLPIDSRYDKANSWHTD---VTFVDRIPKASLLRAVTLPSYGGTTAWAST
MAB_4209c|M.abscessus_ATCC_199 LLNLEG---AANGWHTD---VTFVDRIPKASVLRPVTLPSYGGATTWAST
Mb3440|M.bovis_AF2122/97 ITPINSEFGKANRWHTD---VTFAANYPAASVLRAVSLPSYGGSTLWANT
Rv3406|M.tuberculosis_H37Rv ITPINSEFGKANRWHTD---VTFAANYPAASVLRAVSLPSYGGSTLWANT
MMAR_1141|M.marinum_M ITPINSEWGKANRWHTD---VTFAANYPAASILRAVTLPNYGGSTLWANT
MUL_0904|M.ulcerans_Agy99 ITPINSEWGKANRWHTD---VTFAANYPAASILRAVTLPNYGGSTLWANT
MAV_4353|M.avium_104 ITPIDSEYGKATRWHTD---VTFAANYPAASILRAVTLPSYGGSTLWAST
TH_0024|M.thermoresistible__bu KNSSAAYLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASS
Mvan_4182|M.vanbaalenii_PYR-1 KNSSAAYLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASS
. : ** * * *::* . :. ** * :*.:
Mflv_3107|M.gilvum_PYR-GCK EAAYDRLPAPLRALTENLWAVHTNTYDYAADADARLVPLADTERQ-YREE
MSMEG_3870|M.smegmatis_MC2_155 EAAYQQLPAPLRTLADNLWAVHTNRFDYADSA------ISAEQRG-YRQR
MAB_4209c|M.abscessus_ATCC_199 VAAYEQLPKPLRSLVDDLWATHTNLYDYASSGASG--GVSAERRAAYYTE
Mb3440|M.bovis_AF2122/97 AAAYAELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQRA-FRQV
Rv3406|M.tuberculosis_H37Rv AAAYAELPEPLKCLTENLWALHTNRYDYVT-----TKPLTAAQRA-FRQV
MMAR_1141|M.marinum_M ATAYAELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQQA-FRQA
MUL_0904|M.ulcerans_Agy99 ATAYAELPEPLKCLVENLWALHTNRYDYVANEA--VQALTDTQQA-FRQA
MAV_4353|M.avium_104 VAAYQQLPEPLRHLTENLWALHTNRYDYVR-----NDPMNDTQRA-FRQA
TH_0024|M.thermoresistible__bu YGAYEALSEEEKRHVETLRVVHSLEASQRR--------VTPDPTP-EQLA
Mvan_4182|M.vanbaalenii_PYR-1 YAAYDALTDAEKQRFASLRVVHSLEASQRR--------VNPDPSP-EELA
** *. : * . *: . :
Mflv_3107|M.gilvum_PYR-GCK FVSDYYETEHPVVRVHPETGRKVLLLGHFVKHFVGLGQAESTALLQLLQN
MSMEG_3870|M.smegmatis_MC2_155 FESDYYEVEHPVVRVHPETGERVLLLGHFVKSFVGLKDTESAALFRLFQD
MAB_4209c|M.abscessus_ATCC_199 FTSSRYETVHPVVRVHPETGERSLLLGQFVKSFQDLPSAEFASLFQLLQA
Mb3440|M.bovis_AF2122/97 FEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQR
Rv3406|M.tuberculosis_H37Rv FEKPDFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQR
MMAR_1141|M.marinum_M FQKPDFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQESSALFELLQR
MUL_0904|M.ulcerans_Agy99 FQKPDFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQESSALFELLQR
MAV_4353|M.avium_104 FEKPDFRTEHPVVRVHPETGERALLAGDFVRGFVGLDGHESSVLLELLQR
TH_0024|M.thermoresistible__bu RWRARPTHEHPLVWTH-RNGRKSLVLGASADYVVGMDLDEGRALLADLLD
Mvan_4182|M.vanbaalenii_PYR-1 RWRARPTHEHPLVWTH-RTGRKSLVLGASADYIVGMDPEEGRALLSELLD
**:* .* ..*.: *: * . . .: * *: :
Mflv_3107|M.gilvum_PYR-GCK RVTKLENTIRWSWELGDIAVWDNRATQHYAVSDYDDQFRRLSRVTLAGDI
MSMEG_3870|M.smegmatis_MC2_155 RITRLENTVRWSWKPGDLAIWDNRATQHYAVADYDDQYRRLNRVTLAGDI
MAB_4209c|M.abscessus_ATCC_199 RITKLENTFRWNWRLGDVAIWDNRATQHYGIADFGEQQRELHRVTLAGDV
Mb3440|M.bovis_AF2122/97 RITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDV
Rv3406|M.tuberculosis_H37Rv RITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDV
MMAR_1141|M.marinum_M RITSPENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTLMGDV
MUL_0904|M.ulcerans_Agy99 RITSPENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTLMGDV
MAV_4353|M.avium_104 RITMPENTVRWSWAPGDVAMWDNRATQHRAIDDYDDQPRLMHRITLMGDV
TH_0024|M.thermoresistible__bu RATTEDRVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTVLGDE
Mvan_4182|M.vanbaalenii_PYR-1 RATTADKVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTVLGDE
* * :.. * ** .:****.. * . :. * : * *: **
Mflv_3107|M.gilvum_PYR-GCK PVDVYGRRSRVIAGDASTYSQVVVPLKLAGLAS
MSMEG_3870|M.smegmatis_MC2_155 PVDVYGERSRVIAGDASSYSPVDSPVALAS---
MAB_4209c|M.abscessus_ATCC_199 PVDVHGRRSQILLGDASHYSGIETPQRLELFAA
Mb3440|M.bovis_AF2122/97 PVDVYGQASRVISG---------APMEIAG---
Rv3406|M.tuberculosis_H37Rv PVDVYGQASRVISG---------APMEIAG---
MMAR_1141|M.marinum_M PVDVHGQRSRVISG---------APLALAG---
MUL_0904|M.ulcerans_Agy99 PVDVHGQRSRVISG---------APLALAG---
MAV_4353|M.avium_104 PVNVHGERSRVISG---------APLEVLAS--
TH_0024|M.thermoresistible__bu PIQ------------------------------
Mvan_4182|M.vanbaalenii_PYR-1 PIQ------------------------------
*::