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MSFVSVSPELVIDGAAALTQIGSSIDEANAAAGATTAVLPPGVDEVSVALAALFVAHGREYESLSAQVAL FHRRFVQMLAAASGGYAEAEAANISAVAGLETVEQCVLDVINAPTQALFGWSLIGNGTDGAPGSGQAGGN GGLLWGNGGNGGSGGVGQTGGAGGSAGLLGHGGAGGAGGVSGVSAVGATGGAGGNGGWLYGNGGAGGLGG QGVLTGGNGGAGGAARFFGAGGTGGAGGLGLGDTGGIGGIGGNAGALFGPGGAGGAGGAGGPGGANGTNG GDGGAGGAAGLYGLGGAGGAGGDGGAGLSGGAGDAGGAGGHAGNGGAGGRGGWLVGNGGVGGLGGVGGTG GAGGAGGDGVVLGSAGGTGGDGGVGGTGGVGGTGGEGGFLGQRGAGGAGGAGGAGGLAGDGGRGAAGTFA GGTGIGGAGGDGGNAGVGGAGGAGGAGSVTGAHGAEGARPIGGNGGAGGRGADAIAAGKSGGAGGAGGNG GLFGHGGDGGDGGVGKAGEAGASGLLPGEAGFAGEAGGAGGNGGAGGSGGALAGDGGDGGAGGAGGIGGN GGAGTTGLAGHIGIDMNGGAGGVGGAGGNGGAGGTGGDAGHAQAGGYSDGLQGAGGDGGHGGSGGVAGDG GRGADAAAGSGLAGGDGGRGGDPGAGGEGGAAGGGSVAGTAGLDGIGPTSGGNGGNGGHGGSGAVGVEGG AGSAGGAGGRGGDGGAYGNGGVGGNGGAGGAGSPGAHGGTAGEDGFNAGDGGHGGAGGTGGGGGAKGGVG GAGGSGGVGGQGGTGGDGATGLSGKAGTGTDGESGGRGGHAGNGGNGGDGGAGGVSHAPGFLDGADGAGG SGGAGGNGGNGANGGNGGSAPNPIGFENGHNGGNGGNGGYGAAGGVGGTGGISGDGSTHAAPGDDGIMGN GGHGGHGGDGSRDNPDGGGHPGDGGYGGNGGSGFNAGNGGNGGRGGSAHASLVGKAGNGGFGGTGGNSFG GVSGNGGNGGDGGHALHGQPGGHGGQGGHGGVAHIDGSDYPGWPGLPGDVGYQDGTGGGGGTGGAGGHAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0989 | - | - | 100% (1050) | PE-PGRS family protein |
| M. marinum M | MMAR_3763 | - | 0.0 | 56.67% (1147) | PE-PGRS family protein |
| M. marinum M | MMAR_1829 | - | 0.0 | 55.53% (1149) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1485c | PE_PGRS27 | 0.0 | 55.60% (1099) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 44.62% (845) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1450c | PE_PGRS27 | 0.0 | 49.76% (1234) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-11 | 35.87% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 4e-52 | 31.75% (611) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-23 | 41.52% (171) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-162 | 41.19% (1027) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 6e-50 | 38.04% (347) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 51.03% (1115) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-174 | 47.98% (767) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1485c|M.bovis_AF2122/97 --------------------------------------------------
Rv1450c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0989|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 -----------------------------------------MSLVIVAPE
Rv1450c|M.tuberculosis_H37Rv -----------------------------------------MSLVIVAPE
MMAR_0989|M.marinum_M -----------------------------------------MSFVSVSPE
MUL_4367|M.ulcerans_Agy99 -----------------------------------------MSFVSVGPG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------MSIID
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------------MNIV
Mb1485c|M.bovis_AF2122/97 TVAAAALDVARIGSSIGVANSAAAGSTTSVLAAG----------------
Rv1450c|M.tuberculosis_H37Rv TVAAAALDVARIGSSIGAANAAAAGSTTSVLAAG----------------
MMAR_0989|M.marinum_M LVIDGAAALTQIGSSIDEAN-AAAGATTAVLPPG----------------
MUL_4367|M.ulcerans_Agy99 LLEAAARDLAGLGAGLREANLAAAGATVGVLPAA----------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------MMFLAPPGGPGPISAAIQLTSTG----------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVG-------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTG----------------
Mb1485c|M.bovis_AF2122/97 ----ADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVS
Rv1450c|M.tuberculosis_H37Rv ----ADEVSAAIATLFGSHAREYQAISTQVAAFHDRFAQTLSAAVGSYVS
MMAR_0989|M.marinum_M ----VDEVSVALAALFVAHGREYESLSAQVALFHRRFVQMLAAASGGYAE
MUL_4367|M.ulcerans_Agy99 ----GDEVSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQ
Mflv_5091|M.gilvum_PYR-GCK ------------MVTFGGGA----------------------TPTPTSLG
Mvan_1264|M.vanbaalenii_PYR-1 ----SEATEPWYVVSFGGSG----------------------APTPNNLA
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------AVMPVVAE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------------------------------ADDAATASAP
Mb1485c|M.bovis_AF2122/97 AEATN------AAPLA---TLEHNVLNALNAPTQALLGRPLIGDGAAGAP
Rv1450c|M.tuberculosis_H37Rv AEATN------AAPLA---TLEHNVLNALNAPTQALLGRPLIGDGAAGAP
MMAR_0989|M.marinum_M AEAAN------ISAVAGLETVEQCVLDVINAPTQALFGWSLIGNGTDGAP
MUL_4367|M.ulcerans_Agy99 AEALN------MWPLQ---ELEQQALGVVNAPSMALFGRPSIGNGVDGVA
Mflv_5091|M.gilvum_PYR-GCK AAAVD------LSGTS----------------------CGLICNGQD---
Mvan_1264|M.vanbaalenii_PYR-1 ASLVD------LSGTS----------------------CGLICNGQD---
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGING-T
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SVASN-------------------------------------------YG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DRVIS------------------------------------------AIL
Mb1485c|M.bovis_AF2122/97 GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG---
Rv1450c|M.tuberculosis_H37Rv GTGQAGGAGGILWGNGGAGG-SGAPGQVGGAGGAAGLFGTGGAGGAG---
MMAR_0989|M.marinum_M GSGQAGGNGGLLWGNGGNGG-SGGVGQTGGAGGSAGLLGHGGAGGAGGVS
MUL_4367|M.ulcerans_Agy99 GTGQAGGAGGILWGNGGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGGVG
Mflv_5091|M.gilvum_PYR-GCK GTGQNG---GILFGNGGSGWNSDVVGMDGGNGGNGGLFG-----------
Mvan_1264|M.vanbaalenii_PYR-1 GTGQNG---GILFGNGGSGWNSEIAGVSGGNGGNAGLFG-----------
MSMEG_0868|M.smegmatis_MC2_155 ADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVG---
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 YQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDND------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDN----------
Mb1485c|M.bovis_AF2122/97 ---GAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVG
Rv1450c|M.tuberculosis_H37Rv ---GAGAAGGAGGSGGWLLGNGGVGGAGGQSLLGGATGGAGGNAGLFGVG
MMAR_0989|M.marinum_M GVSAVGATGGAGGNGGWLYGNGGAGGLGGQGVLTGGNGGAGGAARFFGAG
MUL_4367|M.ulcerans_Agy99 AAGMTGGSGGAGGGGGWLWGAGGSGGAAGAGGSGGSGGWLWGNAGQTAGA
Mflv_5091|M.gilvum_PYR-GCK -------------------GNGGNGGNG----LGGGNGGNGGNAGAFALF
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GNGGNGGNG----LGSGDGGNGGDAGLFSLF
MSMEG_0868|M.smegmatis_MC2_155 ---WAGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------FLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ----------------VMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPD
Mb1485c|M.bovis_AF2122/97 G-TGGPGGPGGPGGPGGPGGPGGVGGTGGAGGLGGTLYGAGGHGGAGGPG
Rv1450c|M.tuberculosis_H37Rv G-TGGPGGPGG---------PGGVGGTGGAGGLGGTLYGAGGHGGAGGPG
MMAR_0989|M.marinum_M G-TGGAGGLGL----------GDTGGIGGIGGNAGALFGPGGAGGAGGAG
MUL_4367|M.ulcerans_Agy99 G-VGGAGGAGGAG------DAGDQGVSGVAPGEAGAVGFAGGAGGAGGAG
Mflv_5091|M.gilvum_PYR-GCK G-NGGNGGNGG----------------VGVVGATGAVGAPGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 G-RGGNGGNGG----------------VGIAGATGAVGAPGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGIGGTG-----------GGLFGLLGHSGSTGAAGAAGNGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 P---------------------------LLDLSFGDLQFGNRDTTAIGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TATLAVVETSD----------------GSIPDVYKQQIRAESYGDAAGQL
Mb1485c|M.bovis_AF2122/97 PIGGVG----GHGGVGGAAGLLGVGGHGGAGGHGA-AGIAGAAGKGGIFP
Rv1450c|M.tuberculosis_H37Rv PIGGVG----GHGGVGGAAGLLGVGGHGGAGGHGA-EGVAGAAG-EDLSP
MMAR_0989|M.marinum_M GPGGANGTNGGDGGAGGAAGLYGLGGAGGAGGDGG-AGLSGGAG------
MUL_4367|M.ulcerans_Agy99 GNGVGG----GVNGAGGAGGAGGVGGGGGAGASGVGAGVAGGDG------
Mflv_5091|M.gilvum_PYR-GCK VTSGVV------GGNGEDAVGYGATGAAGAAGAAGAAGAAGAVG------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVT------GGNGADAVGYGATGAAGAAGAAGAAGKAGAVG------
MSMEG_0868|M.smegmatis_MC2_155 NGGFGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVAVGG------SNSGPIASGQGSTAVNGDVRDSNIINADHGSN------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 SAMVAG-----LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAE
Mb1485c|M.bovis_AF2122/97 DGSNGGAGGDAGDGGTGGRGGWLAGAGGAGGDGGIGGTGGAGGAGFSRAL
Rv1450c|M.tuberculosis_H37Rv HGTSGGVGGDAGDGGTGGRGGWLAGAGGAGGAGGVGGTGGAGGAGFSRAL
MMAR_0989|M.marinum_M --DAGGAGGHAGNGGAGGRGGWLVGNGGVGGLGGVGGTGGAG--------
MUL_4367|M.ulcerans_Agy99 --GTGGAGGAAGVGGAAGTGG-TGGAAGVAGTGGDGGDGGAG--------
Mflv_5091|M.gilvum_PYR-GCK ---SAGAAGEAGETGTWGNAGLPGKAGDAGGAGAVGAAGAAG--------
Mvan_1264|M.vanbaalenii_PYR-1 ---SAGTAGSAGAPGVWGNAGLPGAAGAAGGAGAIGTAGVAG--------
MSMEG_0868|M.smegmatis_MC2_155 GAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTG--------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------VGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 EPETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYS--------
Mb1485c|M.bovis_AF2122/97 IVAGDNGGDGGNGGMGGAGGAGGPGGAGGLISLLGGQGAGGDGGDGGAGG
Rv1450c|M.tuberculosis_H37Rv IVAGDNGGD-----------------------------------------
MMAR_0989|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 VGGDRGAGANGNQAVNAGAGGAGGHGGDPGAGGAGGTGGAGSTIGAHGAA
Rv1450c|M.tuberculosis_H37Rv ----------------------------PGAGGAGGTGGAGSTIGAHGAA
MMAR_0989|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 -----------------------------------------------RVI
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNG
Rv1450c|M.tuberculosis_H37Rv GASPTSGGNGGAGGNGAHFSSGGKAGGNGGAGGAGGLVGNGGAGGAGGNG
MMAR_0989|M.marinum_M ----------GAGGDGVVLGSAGGTGGDGGVGGTG---------------
MUL_4367|M.ulcerans_Agy99 ----------GAGSDASLAGQAGFAGGSGGAGGVG---------------
Mflv_5091|M.gilvum_PYR-GCK ----------TVGTAGATGGTG--TGANGGAGGVG---------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------AAGTAGATGGTG--VGGNGGAGQAG---------------
MSMEG_0868|M.smegmatis_MC2_155 AEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAY-------------
TH_3810|M.thermoresistible__bu ---------------------VDGDGGSGGRT------------------
MAB_4284c|M.abscessus_ATCC_199 ----------QRNTTNINDSFNTDRSTNIGSGNTTN--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------LPDYLYVPVDPEPGDDELAYSAVGEED---------------
Mb1485c|M.bovis_AF2122/97 APGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNG
Rv1450c|M.tuberculosis_H37Rv APGAPPSGGDPNGGGGGAGGAGGKGGDGGAQAGDGGAGGAGGKGGNGGNG
MMAR_0989|M.marinum_M --------------------------------------------------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 ATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSM
Rv1450c|M.tuberculosis_H37Rv ATGATGLNGLGAGADGTDGGKGGNGGAGGGGGAGGQGGKALAATHQDGSM
MMAR_0989|M.marinum_M ----------------------GVGGTGGEGGFLGQRG------------
MUL_4367|M.ulcerans_Agy99 ----------------------GSAGAGGVNGSGGDGG------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------GVGGTGAAGAAGGAGG------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GIGGTGAAGAAGQAGT------------
MSMEG_0868|M.smegmatis_MC2_155 ----------------------GNNGAVSGTATGGRGGDG----------
TH_3810|M.thermoresistible__bu -------------------------GLFSKLSRGGDGG------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------TEIGSHNQANIGTSTS------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------AESPTVVIEKLFLPEDS------------
Mb1485c|M.bovis_AF2122/97 GAGGAGGNGGAG----GMGGDGGNGAKGTFDNGGDGVGGNGGNGGSRGIG
Rv1450c|M.tuberculosis_H37Rv GAGGAGGNGGAG----GMGGDGGNGAKGTFDNGGDGVGGNGGNGGSRGIG
MMAR_0989|M.marinum_M -AGGAGGAGGAG----GLAGDGGRGAAGTFA-GGTGIGGAGGDGGNAGVG
MUL_4367|M.ulcerans_Agy99 -AGAAGGAGGASATVAGSGGVGGDGGAGGAAGGGVGAASLGGDGGHAGAG
Mflv_5091|M.gilvum_PYR-GCK -LGETGTTGGAG----GVGGQGTAGGTGGVG----GIGGAGSTGAVGGVG
Mvan_1264|M.vanbaalenii_PYR-1 -AGETGVTGGVG----GIGGQGTEGGTGGVG----GVGGVGATGGAGGVG
MSMEG_0868|M.smegmatis_MC2_155 IDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQ
TH_3810|M.thermoresistible__bu -DGGLGGNGGHG----------------------------GGTGIISLLS
MAB_4284c|M.abscessus_ATCC_199 -AGGSAAVGGNA-----------------------GLAGNAGLAGNAGLA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -EPRRRPVLLVG-------------------------SGLAVVGISAVLA
Mb1485c|M.bovis_AF2122/97 GAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANATVAGGAGGAGGKG
Rv1450c|M.tuberculosis_H37Rv GAGGIGGAGSTAGADGARGATPTSGGNGGTGGNGANATVAGGAGGAGGKG
MMAR_0989|M.marinum_M GAGGAGGAGSVTGAHGAEGARP-IGGNGGAGGRGADAIAAGKSGGAGGAG
MUL_4367|M.ulcerans_Agy99 GAGGEGLSGGFN-----TGAAGGIGGAGGAGGTGGDSGGVGGVNGDGGAG
Mflv_5091|M.gilvum_PYR-GCK GKGIQGGQ----------GLQGGKGGDGGAGGKGGDADSMGSAGATGGKG
Mvan_1264|M.vanbaalenii_PYR-1 GKGIQGGQ----------GLQGGQGGDGGTGGTGGDATSMGEAGATGGKG
MSMEG_0868|M.smegmatis_MC2_155 AGYGPTTGGKASG--TAKAGHGGKASDGGKGGNGGDALVMA-AGATGVAT
TH_3810|M.thermoresistible__bu -----------------------LAGNGGNGGNG--YRTTDNNALDGGHG
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGN-------------AGLAGNAGLAGNAGLAGNAGLAGNAG-LA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LEIALAIG-------------IRTTGTVALQPTPNQHLIVPTEQAPAPPP
Mb1485c|M.bovis_AF2122/97 GNGGLVGNGGA-GGKGGDGMAGVAGSSPTTAGESGTSGQNGGAGGA--GG
Rv1450c|M.tuberculosis_H37Rv GNGGLVGNGGA-GGKGGDGMAGVAGSSPTTAGESGTSGQNGGAGGA--GG
MMAR_0989|M.marinum_M GNGGLFGHGGD-GGDGGVGKAGEAGASGLLPGEAGFAGEAGGAGGN--GG
MUL_4367|M.ulcerans_Agy99 GGGGRGGDGGSSTSTSGVGGAGGAGGNGGNAGFGVSAGGTGGSAGD--GG
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGRGGL------FGKGGNAGN-----------GADGGTGGA--GG
Mvan_1264|M.vanbaalenii_PYR-1 GNGGNGGRGSL------FGRGGNAGN-----------GGNGGTGGN--GG
MSMEG_0868|M.smegmatis_MC2_155 GNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGG
TH_3810|M.thermoresistible__bu GNGGNVGFFSL------FNLGG-----------------AGGWGGS----
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGL--------------------------AGNAGLAGN----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 VQASAPQPKIS-------------------------VPEPVAAPKP----
Mb1485c|M.bovis_AF2122/97 AGGRGGDFGGDGGTGGAGGNGADGGAGGNGANGANATTPGAKGG----DG
Rv1450c|M.tuberculosis_H37Rv AGGRGGDFGGDGGTG---------GAGGNGANGANATTPGAKGG----DG
MMAR_0989|M.marinum_M AGGSGGALAGDGGDGGAG------GAGGIGGNGGAGTTGLAGHIGIDMNG
MUL_4367|M.ulcerans_Agy99 AGGGAGGVDGVGGASGNG------GAAGAGGAGGSGIGAGIDGG----AG
Mflv_5091|M.gilvum_PYR-GCK AGGTGG-------------------TGGAGGTGG--------------TG
Mvan_1264|M.vanbaalenii_PYR-1 NGGTGG-------------------TGGNGGTGG--------------TG
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGWVQAYDP----------NGPAGTTIDKGKAAGGNGG----DG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------A
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ------------------------------------------------LS
Mb1485c|M.bovis_AF2122/97 GHGGPGAQGGNGGQGGPGGLAGNLFG---QNGIQGVGGSGGKGGAGGLAG
Rv1450c|M.tuberculosis_H37Rv GHGGPGAQGGNGGQGGPGGLAGNLFG---QNGIQGVGGSGGKGGAGGLAG
MMAR_0989|M.marinum_M GAGGVGGAGGNGGAGGTGGDAGHAQAGGYSDGLQGAGGDGGHGGSGGVAG
MUL_4367|M.ulcerans_Agy99 GAGGTGGAAGFPGGGGTTGAWG-------TGGAGGAGGAGGAGDHGGVGV
Mflv_5091|M.gilvum_PYR-GCK GTGGIGGAGSTGGTGGTGGTGG-------TGGTGGTGGTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGIGGAGSTGGTGGTGGTGG-------TGGTGGTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GFNGTGGATGGRGGDGAGASVWKANG-QHSTGQTDTGGNGGRGGDGGTFV
TH_3810|M.thermoresistible__bu GVDGVDVVGGNPDGG--------------------TPGAHGESHTPGVYT
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAG----------NAGLAGNAGLAGNAGLAG
MLBr_01183|M.leprae_Br4923 ---------------------------------------------MPLFL
MAV_4827|M.avium_104 PPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPV
Mb1485c|M.bovis_AF2122/97 DGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFT
Rv1450c|M.tuberculosis_H37Rv DGGNGANGNFAFGDGNGGHGGNGGNPGAGGQGGSGGAGSTPGAKGAHGFT
MMAR_0989|M.marinum_M DGGRGADAAAGSG-LAGGDGGRGGDPGAGGEGGAAGGGSVAGTAGLDGIG
MUL_4367|M.ulcerans_Agy99 NPGDSGTAGWAGG--AGGAGGAGGSAAFNGVNGAGGAGGNGGAGGGGGAG
Mflv_5091|M.gilvum_PYR-GCK KGGTGG---------TGGAGGTGGDGGTGGTGGTGGTGGTGGTGGTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 KGGTGG---------TGGDGGTGGTGGTGGTGGTGGTGGTGGTGGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 NAGANGNGGAGG--AGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVG
TH_3810|M.thermoresistible__bu DR-------------QGEDGEDGTGTGIGGRGGNGGSSSGTHPMAEDGE-
MAB_4284c|M.abscessus_ATCC_199 NAG------------LAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVL
MLBr_01183|M.leprae_Br4923 NA--------------EPQALTAAANTLEGLSAATVASNAAAAQLTTEIA
MAV_4827|M.avium_104 PDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTP
.
Mb1485c|M.bovis_AF2122/97 PTSGGDGGDGGNGGHSQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGAFG
Rv1450c|M.tuberculosis_H37Rv PTSGGDGGDGGNGGNSQVVGGNGGDGGNGGNGGSAGTGGNGGRGGDGAFG
MMAR_0989|M.marinum_M PTSGGNGGNGGHGGS----GAVGVEGGAGSAGGAGGRGGDGG-----AYG
MUL_4367|M.ulcerans_Agy99 ASGIGAGVAGGDGGT----GGTGGAAGTGGAAGTGGTGGAAG-----AAG
Mflv_5091|M.gilvum_PYR-GCK DGTGGTGGTGGTGGQ----GGQGGQGGTGGTGGQGGLGGGGG--------
Mvan_1264|M.vanbaalenii_PYR-1 DGLGGTGGTGGTGGF----GGQGGQGGTGGTGGQGGLGGVGG--------
MSMEG_0868|M.smegmatis_MC2_155 LGNGGKGGNGGNGGN----GGTYVDPSHTGAGGNGGNGGAGRIRVNNGTA
TH_3810|M.thermoresistible__bu HVKALDGRPGLDGGN----GSHGGNGGHGGRGGFLGIGGSGG--------
MAB_4284c|M.abscessus_ATCC_199 NTGVSGAIGGSSHVG------GAINESLGGSGSVGGSTAVGG--------
MLBr_01183|M.leprae_Br4923 PPAADDVS-------------ILLAHFFSGHGRQ----------------
MAV_4827|M.avium_104 PGEGTPPKPDGPGNYG---GGHVPTPGAGGSGGSGGGHVPTPG-------
. .
Mb1485c|M.bovis_AF2122/97 GMSANATNPGENGPNGNPGGNGGAG-GAGGAGLNGGNGGAGGNGGLGGFG
Rv1450c|M.tuberculosis_H37Rv GMSANATNPGENGPNGNPGGNGGAG-GAGGAGLNGGNGGAGGNGGLGGFG
MMAR_0989|M.marinum_M --------------NGGVGGNGGAG-GAGSPGAHGGTAGEDG------FN
MUL_4367|M.ulcerans_Agy99 -----------SAGDGGAGGAGGAG-DDGSAGVVSGDPGTAG--------
Mflv_5091|M.gilvum_PYR-GCK --------------TGGQGGTGGTG-GQGGTGGTGGTGGTGG--------
Mvan_1264|M.vanbaalenii_PYR-1 --------------TGGTGGTGGTG-GQGGTGGTGGTGGTGG--------
MSMEG_0868|M.smegmatis_MC2_155 TG----------TATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGS
TH_3810|M.thermoresistible__bu --------------WGGHGGNGGDTDADGGNGGDGGNGGSAG--------
MAB_4284c|M.abscessus_ATCC_199 ---------------GAHTGVGGGVSTGVGVGSHVGGGISES--------
MLBr_01183|M.leprae_Br4923 --------------YQAHASQGATNHQDLIQSLLTSSSAYAG--------
MAV_4827|M.avium_104 --------------AGGSGGSGGGHVPTPGTGGPGGTGGSGG--------
. *. . .
Mb1485c|M.bovis_AF2122/97 GNGAAGANGVAVGAPGQPGGAGGHGG-AGGNGGAGG-------------N
Rv1450c|M.tuberculosis_H37Rv GNGAAGANGVAVGAPGQPGGAGGHGG-AGGNGGAGG-------------N
MMAR_0989|M.marinum_M ------------------AGDGGHGG-AGGTGGGGG-------------A
MUL_4367|M.ulcerans_Agy99 ----------------KAGGAGGAGG-VGGNGVAGG-------------V
Mflv_5091|M.gilvum_PYR-GCK -----------------TGGAGGDGG-LGGLGGFGG-------------S
Mvan_1264|M.vanbaalenii_PYR-1 -----------------TGGAGGDGG-LGGLGGFGG-------------V
MSMEG_0868|M.smegmatis_MC2_155 NASG-----------TATGGDGGNGGTLGATNGTGGAATIVAYNVVQANP
TH_3810|M.thermoresistible__bu -----------------RGGTGGLRGVFGINGGNGR--------------
MAB_4284c|M.abscessus_ATCC_199 -----------------LGGSGSVGGSTAVGGG-----------------
MLBr_01183|M.leprae_Br4923 ------------------TETANHDS-L----------------------
MAV_4827|M.avium_104 -------------------GHVPTPG-AGTPGGSGG--------------
.
Mb1485c|M.bovis_AF2122/97 GGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGG
Rv1450c|M.tuberculosis_H37Rv GGQGVVSDGAGGAGGAGGDGGAPGDGANGGNGQGAGAFAGGGGGRGGDGG
MMAR_0989|M.marinum_M KG-GVG--GAGGSGGVGGQGGTGGDGATGLSGKAGTGTDGESGGRGGHAG
MUL_4367|M.ulcerans_Agy99 NGSGGAG-GAGGAGGTGG-AGASGVPASVDGGDGGAGGAGGAAGTGGSGG
Mflv_5091|M.gilvum_PYR-GCK GG-------TGGQGGLGGPGGSTG-GAGGAGGQAGTAGKGGLFGGSGSAG
Mvan_1264|M.vanbaalenii_PYR-1 GG-------TGGQGGQGGPGGSTG-GAGGAGGQAGVAGKGGLFGGSGSAG
MSMEG_0868|M.smegmatis_MC2_155 QASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGI
TH_3810|M.thermoresistible__bu ----------AGLGGRGXXXXGGGVGAAVRSGN-GVFSGGGGTPSAGFGV
MAB_4284c|M.abscessus_ATCC_199 ----------AHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------GHLPFPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPA
Mb1485c|M.bovis_AF2122/97 NAGNAGAGGPGGTGSTAGKAGP-AGSILHDGGNGGHGGHGAASGGNGGPG
Rv1450c|M.tuberculosis_H37Rv NAGNAGAGGPGGTGSTAGKAGP-AGSILHDGGNGGHGGHGAASGGNGGPG
MMAR_0989|M.marinum_M NGGNGGDGGAGGVSHAPG---------FLDGADG--------------AG
MUL_4367|M.ulcerans_Agy99 SAGNTGAGGAGGAGGAGG-------SAASTGVNG-----------DGGAG
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGASGGKGAQG----------ATGAQG--------------AT
Mvan_1264|M.vanbaalenii_PYR-1 TAGVTGASGASGGKGAQG----------ATGAQG--------------AT
MSMEG_0868|M.smegmatis_MC2_155 DGGLGGNGGDGVVNTTANAANPGSATGTATGGDG------------GKAT
TH_3810|M.thermoresistible__bu PTTIQFPAGSCTSR----------------------------------AV
MAB_4284c|M.abscessus_ATCC_199 GGAHTGVGGGVNTGVGVG------------------------------SH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGGGLGGGGGHAPAPGGG------------------------------LG
Mb1485c|M.bovis_AF2122/97 GHGGNGGNGG-TGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
Rv1450c|M.tuberculosis_H37Rv GHGGNGGNGG-TGANGGNGGIGGTGGAGSTGAKGVLGTNEGDGGDGGRGG
MMAR_0989|M.marinum_M GSGGAGGNGG-NGANGGNGGS----------APNPIGFENG--HNGGNGG
MUL_4367|M.ulcerans_Agy99 GAGGVGGLGGDSAATAGGGGAGGDGGKGGAGGAGVNGVGGGDGGKGGTGG
Mflv_5091|M.gilvum_PYR-GCK GAQGATGATGAAGKAGATGAAG---------AAGAAGSAGTTGAQGSAGT
Mvan_1264|M.vanbaalenii_PYR-1 GAQGATGATGASGAQGSAGSAG---------SAGVAGSAGTTGAQGSAGT
MSMEG_0868|M.smegmatis_MC2_155 GTASQGGNGGPSWVQSGYGSTLG-----GNATGTATAGKGGEASNGGVAG
TH_3810|M.thermoresistible__bu SREGIMPSSRAASARAG--------------AACASSTSRSRRSFCCSRA
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGGSGSVGGSTAVGG--------GAHTSAINDALGGSGSVGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GFGGGHSGGGLGGLGGGHK-------------------------------
Mb1485c|M.bovis_AF2122/97 NGGRGGNGGQGLT-GAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGG
Rv1450c|M.tuberculosis_H37Rv NGGRGGNGGQGLT-GAGGNGGTGGTPGNGGNGGNGASGDLVTSPGDGGGG
MMAR_0989|M.marinum_M NGGYG---------AAGGVGGTGGISGDGST---------HAAPGDDGIM
MUL_4367|M.ulcerans_Agy99 AGGAGGAGSDGIIPSNGGLGGNGGNGGNGGQ-----------AFGDG-VG
Mflv_5091|M.gilvum_PYR-GCK NGANG----------ANGSQGAAGKAG---------------ATGTTGAT
Mvan_1264|M.vanbaalenii_PYR-1 NGANG----------ANGSQGAAGKAG---------------ATGTTGAT
MSMEG_0868|M.smegmatis_MC2_155 NGGNALVMAAGTTGVATGNTATGGDGGAATT-----------AGATGGAG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STAVG-------------------------------------GGAHTSAI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GRGGDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGT------GGTGGQGAN
Rv1450c|M.tuberculosis_H37Rv GRGGDAGRGGDAGLGGSSGPGGTPGDWGTGGTGGT------GGTGGQGAN
MMAR_0989|M.marinum_M GNGGHGGHGGDGSRDNPDG-GGHPGDGGYGGNGGS------GFNAGNGGN
MUL_4367|M.ulcerans_Agy99 GAGGIGGKGGNAAIGTIVINGGVGGAGGSGGLGGA------TEDGVGGVG
Mflv_5091|M.gilvum_PYR-GCK GAAGEDGDAGSGGSGINGGAGGAGGAGGEGGEGGD------GGKGGAGAE
Mvan_1264|M.vanbaalenii_PYR-1 GAAGDAGDPGSEAVDINGGAGGAGGAGGEGGEGGA------GGAGGDGSE
MSMEG_0868|M.smegmatis_MC2_155 GFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSK
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NESMNSSINASHSSSMNESFGSSMGSHGAAGTGFE---------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGLTGGRGGTGGNGG---------AGGTGGTGHNGSQPGMGGNGGAGG--
Rv1450c|M.tuberculosis_H37Rv GGLTGGRGGTGGNGGNGNTGGTGGAGGTGGTGHNGSQPGMGGNGGAGG--
MMAR_0989|M.marinum_M ----GGRGGS----------------------AHASLVGKAGNGGFGG--
MUL_4367|M.ulcerans_Agy99 --CAGGAGGNGGRGD-----------------MLFTVGGSGGTGGDGG--
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------GGAGGGGG--
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------GGAGGSGG--
MSMEG_0868|M.smegmatis_MC2_155 IANSSAVAGNGGDGG-----------------VNGTGGASGGDGGNGGNT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 ---FGGNGFA-GVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGG
Rv1450c|M.tuberculosis_H37Rv ---FGGNGFA-GVGGRGGMGGSGGTGGTGDAGPFGTGTGGTGGHGGQGGG
MMAR_0989|M.marinum_M ---TGGNSFG-GVSGNGGNGGDGGHALHGQP----------GGHGGQGGH
MUL_4367|M.ulcerans_Agy99 ---GGGSASGSGTGGSGGTGGVGGIGGDGKLG-------GFGGDGGDGGD
Mflv_5091|M.gilvum_PYR-GCK ---AGGSGAG-GAGGAGGSGGSGGS----------------GGSGGSGGA
Mvan_1264|M.vanbaalenii_PYR-1 ---AGGSGTG-GAGGAGGSGGSGGS----------------GGAGGSGGA
MSMEG_0868|M.smegmatis_MC2_155 SVWKSGGQTADGEHNTGGNGGNGGDGSEPGPG--------GNGAGGAGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----AQGHAQGHASETAHTTLPGAEHH----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb1485c|M.bovis_AF2122/97 GGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
Rv1450c|M.tuberculosis_H37Rv GGFSILLGLGGLGGLGSPGSIATGTAGGAGGGGGFGGLGGGEFV
MMAR_0989|M.marinum_M GGVAHIDGSDYPGWPGLPG--DVGYQDGTGGGGGTGGAGGHAP-
MUL_4367|M.ulcerans_Agy99 GGFGVIGGQGGGGGFGGLGGTGAGGAPSDKGINGEPGNPG----
Mflv_5091|M.gilvum_PYR-GCK AGDSDD--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 AGDSD---------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGG-TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP---
TH_3810|M.thermoresistible__bu --------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------