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SFVSVAPEAVATAASDLARIGSSIDAVNAAAAGATTTVLAAGADEVSVAIAALFGTHAQEYQAISTRISA LNERFVALLTAGNNSYAASESASVSWLQAVEQDVLGLVNAPSQNWFGRPLIGNGADGVAGTGQAGGAGGI LWGNGGAGGSGAVGQSGGAGGSAGLLGHGGAGGAGGQAGASGTGGVGGAGGAGGWLYGNGGTGGVGGEGP VNGGVGGAGGRAWLLGAGGSGGAGGQGLGLNGGAGGAGGNGGLFGIGGTGGAGGDSAGSGSAGAGGDGGH GGLWGRGGAGGIGGVNSDSGDGGAGGGGGAGGRLFGSGGAGGAGGTGAVAGSGGDGGAGGAAVGLWGLGG HGGAGGDGAVGLAGGVGEAGGEGGSAGNGGAGGLGGWLIGSGGAGGLGGVGGAGGAGGAGAAGIAPGSNG GNGGNGGVGGAGGVGGSGGQGGFLRFLGGQGDGGAGGAGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGD NGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGVAGGAGGAGGDGGLYGNGGAGGD GGNGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMGGVLGGHGGAGGIGGVGATGGSGGLGATGAEGV TGGNLHGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFADGTEGVGGAGGEGGAGGVAGDGGKGADAAAFSG AAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPITGGNGGDGGNGASGPAASAGVAGGAGGAGGDG GLYGNGGAGGDGGNGVAGGQGADATAAGASGENGGDGGAGGMGGAGGMGGVLGGHGGAGGIGGVGATGGS GGLGATGAEGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFADGTEGAGGAGGEGGAGGVAGDG GKGADAAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPTTGGNGGDGGSGGSGFQGVKGG AGGVGGDGGLYGNGGTGGTGGTGGIGFNGSTTIGGGNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGTGG VGGTGGTGGSGGTGTSGIFSSANGGDGGNGGDGGTGGTGGVGGLGGQAQAAGFADGTQGVGGAGGVGGTG GNAGNGGHGANADVGSGKAGGNGGDGGDPGVGGIGGQGGAGSIAGVEGAAGVAPTSGGNGGDGGNGASGA TGVNGGAGGSGGDGGLYGNGGDGGDGGNGGKGQVGSTGPVAGSAGGTGGTGGTGGQGGAGGSGGALAGHG GDGGSGGDGGTGGTGGTGRNGANGITGADIDGGSGGKGGNGGTGGAGGAGGQGGQAQAAGYSDGTQGVGG AGGDGGTAGIGGDGGDGANAVAGSGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGSGVTTGGNGGD GGDGGSGAIGVKGGAGGAGGDGGLYGNGGNGGDGGTGGKGTVGDSGATLSADGDRGGAGATGGVGGAGGD GGAKGGNGGLGGSGGTGGMGGTGGDGAHGADMASGSGANGGYGGYGGFGGVGGAGGTGGVGGQAHAAGFT DGATGAGGDGGQGGTGGLGAWGGNGGDGADGSISGPPQNGGKGGDGGGGGPGGLGGQGGLSGDGSSTGAA GELGTFGNGGSGGNGGIGGNATGFNAPGTGGAGGNGGNGAFGGSGGTGGRGGSSSVGTGGAGGDGGDGGM GFGGIGGGGGTGGQGGSGVDAQGIGGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPPFG GSSGGTGGTGGTGGAGGDRFVDTELVGIGGAGHGGVTGGGPTGPALVDGGTGGAGGSGGTGAH*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3763 | - | - | 100% (1814) | PE-PGRS family protein |
M. marinum M | MMAR_2656 | - | 0.0 | 63.32% (1843) | PE-PGRS family protein, PE_PGRS50 |
M. marinum M | MMAR_1829 | - | 0.0 | 56.48% (1914) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 49.17% (1991) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 48.92% (789) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 48.64% (2017) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 1e-09 | 31.52% (92) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 5e-52 | 33.72% (430) | hypothetical protein MAB_4284c |
M. avium 104 | MAV_4827 | - | 9e-26 | 42.35% (196) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-168 | 40.26% (1083) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-47 | 42.23% (296) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 50.18% (1118) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 0.0 | 48.51% (804) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3763|M.marinum_M ---MSFVSVAPEAVATAASDLARIGSSIDAVNAAAAGATTTVLAAGADE- Rv3508|M.tuberculosis_H37Rv ---MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADE- MUL_4367|M.ulcerans_Agy99 ---MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDE- Mb3541|M.bovis_AF2122/97 ---MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADE- MSMEG_0868|M.smegmatis_MC2_155 --------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPK- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQ- MLBr_01183|M.leprae_Br4923 --MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADD- MAV_4827|M.avium_104 MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDR Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 -------MMFLAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTP MMAR_3763|M.marinum_M -VSVAIAALFGTHAQEYQAISTRISALNERFVALLTAGNNSYAASESASV Rv3508|M.tuberculosis_H37Rv -VSARIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA-- MUL_4367|M.ulcerans_Agy99 -VSAAIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNM Mb3541|M.bovis_AF2122/97 -VSARIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATN- MSMEG_0868|M.smegmatis_MC2_155 -FPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -VGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSI MLBr_01183|M.leprae_Br4923 -VSILLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN- MAV_4827|M.avium_104 VISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLV Mflv_5091|M.gilvum_PYR-GCK TSLGAAAVDLSGTSCG---------LICNGQD---GTGQNG---GILFGN Mvan_1264|M.vanbaalenii_PYR-1 NNLAASLVDLSGTSCG---------LICNGQD---GTGQNG---GILFGN MMAR_3763|M.marinum_M SWLQAVEQDVLGLVNAPSQNWFGRPLIGNGADGVAGTGQAGGAGGILWGN Rv3508|M.tuberculosis_H37Rv ----AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLLFGN MUL_4367|M.ulcerans_Agy99 WPLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGILWGN Mb3541|M.bovis_AF2122/97 -----VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGDGGLLFGS MSMEG_0868|M.smegmatis_MC2_155 TSTNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLD MLBr_01183|M.leprae_Br4923 -------HDSL--------------------------------------- MAV_4827|M.avium_104 SAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQ Mflv_5091|M.gilvum_PYR-GCK -GGSGWNSDVVGMDGGNGGNGGLFG------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -GGSGWNSEIAGVSGGNGGNAGLFG------------------------- MMAR_3763|M.marinum_M -GGAGG-SGAVGQSGGAGGSAGLLGHGGAGGAGGQA-------------- Rv3508|M.tuberculosis_H37Rv -GGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLF MUL_4367|M.ulcerans_Agy99 -GGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG---------------- Mb3541|M.bovis_AF2122/97 -GGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLY MSMEG_0868|M.smegmatis_MC2_155 TLGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDP---AMRTTVNPQAQ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LSFGDLQFGNRDTTAIGDGAVAVGGSN----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 QIRAESYGDAAGQLSAMVAGLEKLESLPGG-------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------GNGGNG------------------ Mvan_1264|M.vanbaalenii_PYR-1 --------------------------GNGGNG------------------ MMAR_3763|M.marinum_M -------GASGTGGVGGAGGAGGWLYGNGGTGGVGGEGPVNGGVGGAGGR Rv3508|M.tuberculosis_H37Rv GVGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAEL MUL_4367|M.ulcerans_Agy99 -VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAGAGG----------- Mb3541|M.bovis_AF2122/97 GRGGVGGAGGIGGGTGGAGG-HAWLFGHGGTGGIGGGPGGNGG------- MSMEG_0868|M.smegmatis_MC2_155 LPVPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLG------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------------GNGLGGGNGGNGGNAGAF--------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------GNGLGSGDGGNGGDAGLF--------------- MMAR_3763|M.marinum_M AWLLG--AGGSGGAGGQGLGLNGGAGGAGGNGGLFGIGGTGGAGGDSAGS Rv3508|M.tuberculosis_H37Rv LFGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQ---- MUL_4367|M.ulcerans_Agy99 ---------------------------SGGSGGWLWG------------- Mb3541|M.bovis_AF2122/97 -------WLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAG----- MSMEG_0868|M.smegmatis_MC2_155 ----GVINTISGQYLIGNGINGTADNPNGGTGGLLFGDGGHGYDGS---- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -----------------SGPIASGQGSTAVNGDVRDSN------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------ALFGNGG Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------SLFGRGG MMAR_3763|M.marinum_M GSAGAGGDGGHGGLWGRGGAGGIGGVNSDSGDGGAGGGGGAGGRLFGSGG Rv3508|M.tuberculosis_H37Rv -GGAGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGG MUL_4367|M.ulcerans_Agy99 ------------------NAGQTAGAG-----------------VGGAGG Mb3541|M.bovis_AF2122/97 -GTGGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGG--WLLGNGG MSMEG_0868|M.smegmatis_MC2_155 ------------------AAGLAGGNGGNAG-------------LFGNGG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------IINADH MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ------------------------------------------LLLVGSG- Mflv_5091|M.gilvum_PYR-GCK NGGNGGVGVVGATG------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 NGGNGGVGIAGATG------------------------------------ MMAR_3763|M.marinum_M AGGAGGTGAVAGSGGDGGAGGAAVGLWGLGGHGGAGGDGAVGLAGGVGEA Rv3508|M.tuberculosis_H37Rv QGGTGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGA MUL_4367|M.ulcerans_Agy99 AGGAGDAGDQGVSG------------------------------------ Mb3541|M.bovis_AF2122/97 NGGLGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGG MSMEG_0868|M.smegmatis_MC2_155 NGGVGWAGLDGGNGGSGGLLMG---------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSNVGVDQSQTRVGG----------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 VDVAPLKQVLQTTT------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -----------------------------AVGAPGVAGATGATGVTSGVV Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------AVGAPGVAGATGATGVTSNVT MMAR_3763|M.marinum_M GGEGGSAGNGGAGGLGGWLIGSGGAGGLGGVGGAGGAGGAGAAGIAPGSN Rv3508|M.tuberculosis_H37Rv VGV--------GGTGGQGGAGGAGAAGADAPASTGLTGGTGFAGG-AGGV MUL_4367|M.ulcerans_Agy99 -------------------------------VAPGEAGAVGFAGG-AGGA Mb3541|M.bovis_AF2122/97 TG---------GDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGGA MSMEG_0868|M.smegmatis_MC2_155 ------------------------------IGGAGGAGGVGADGTSAHVD TH_3810|M.thermoresistible__bu ------------------------------------------------VD MAB_4284c|M.abscessus_ATCC_199 -----------------------------DYTNVSGHGSADIDKSVTVVD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------FLDVSVAEEPETALARGAALAAANAPLF Mflv_5091|M.gilvum_PYR-GCK GGNGED-AVG-----------------------YGATGAAGAAGAAG--- Mvan_1264|M.vanbaalenii_PYR-1 GGNGAD-AVG-----------------------YGATGAAGAAGAAG--- MMAR_3763|M.marinum_M GGNGGNGGVGGAGGVGGSGGQGGFLRFLGGQGDGGAGGAGGAGGVAGDGG Rv3508|M.tuberculosis_H37Rv GGQGGNAIAGG---------------------INGSGGAGGTGGQGGAGG MUL_4367|M.ulcerans_Agy99 GGAGGNGVGGG---------------------VNGAGGAGGAGGVGGGGG Mb3541|M.bovis_AF2122/97 GGAGGNGGAGGQAAL-----------------LFGRGGTGGAGGYGGDGG MSMEG_0868|M.smegmatis_MC2_155 GGTGGTGGTGG-----------------------GTGGTGGIGGTGG--- TH_3810|M.thermoresistible__bu ----GDGGSGG-----------------------RTG------------- MAB_4284c|M.abscessus_ATCC_199 DHSQRNTTNIN--------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ASSTAALAYAQ--------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------AAGAAGAVG------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------AAGKAGAVG------------------- MMAR_3763|M.marinum_M KGADAAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPITG Rv3508|M.tuberculosis_H37Rv MGGSGADNASG---------IGADGGAGGTGGNAGAGGAGGAAG------ MUL_4367|M.ulcerans_Agy99 AGASGVG-------------AGVAGGDGGTGGAGGAAGVGGAAG------ Mb3541|M.bovis_AF2122/97 GGGDGFDGTMAG--------LGGTGGSGGTGGDGGAPGNGGAGG------ MSMEG_0868|M.smegmatis_MC2_155 ---------------------GLFGLLGHSG------------------- TH_3810|M.thermoresistible__bu ----------------------LFSKLSR--------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------------DSFNTDRSTN------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------------SAGAAGEAG----ETGTWGN--------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------SAGTAGSAG----APGVWGN--------------- MMAR_3763|M.marinum_M GNGGDGGNGASGPAASAGVAGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQ Rv3508|M.tuberculosis_H37Rv ---TGGTGGVVGAAGKAGIGGTGG----QGGAGGAGSAGTDATA------ MUL_4367|M.ulcerans_Agy99 ---TGGTG------GAAGVAGTGG----DGGDGGAGGAGSDASL------ Mb3541|M.bovis_AF2122/97 ---AGQLLSHSGVAGASGKGGAGG----TGGNGGAGSAGADAPAG----- MSMEG_0868|M.smegmatis_MC2_155 ---------------STGAAGAAG----NGGDGGNGGFGYVLIAG----- TH_3810|M.thermoresistible__bu -----------------------------GGDGGDGGLG----------- MAB_4284c|M.abscessus_ATCC_199 -----------------------------IGSGNTTN------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ------AGLPGKAGDAGGAGAVGAAG----------AAGTVGTAGATGGT Mvan_1264|M.vanbaalenii_PYR-1 ------AGLPGAAGAAGGAGAIGTAG----------VAGAAGTAGATGGT MMAR_3763|M.marinum_M GADATAAGASGENGGDGGAGGMGGAGGMGGVLGGHGGAGGIGGVGATGGS Rv3508|M.tuberculosis_H37Rv ------TGATGGTGFSGGAGGAGGAGGNTGVG-GTNGSGGQGGTGGAGGA MUL_4367|M.ulcerans_Agy99 ------AGQAG---FAGGSGGAGGVGGSAGAG-GVNGSGGDGGAGAAGGA Mb3541|M.bovis_AF2122/97 ------SGAMGSTGFAGGAGGDGGNGGGSGASQGNGGNGGNGGTGGKGGT MSMEG_0868|M.smegmatis_MC2_155 ------PNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILI TH_3810|M.thermoresistible__bu ------------------------------------GNGGHGGGTGIISL MAB_4284c|M.abscessus_ATCC_199 ---------------------------------TEIGSHNQANIGTSTSA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------------------DPGTGAVDQYSLPDYL Mflv_5091|M.gilvum_PYR-GCK G------------------------------TGANGGAG----------- Mvan_1264|M.vanbaalenii_PYR-1 G------------------------------VGGNGGAG----------- MMAR_3763|M.marinum_M GGLGATGAEGVTGGNLHGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFADG Rv3508|M.tuberculosis_H37Rv GGAGGVGAD---------NPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGT MUL_4367|M.ulcerans_Agy99 GGASAT----------------VAGSGGVGGDGGAGGAAG---------- Mb3541|M.bovis_AF2122/97 GGAGMNSLDPL-------LAAQDGGQGGTGGTGGNAGAGGTGFTQGADGN MSMEG_0868|M.smegmatis_MC2_155 GANGGTVDGHA-----------------IGGNGGNGGNGS---------- TH_3810|M.thermoresistible__bu LS--------------------------LAGNGGNGGNGY---------- MAB_4284c|M.abscessus_ATCC_199 GG--------------------------SAAVGGNAGLAG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 YVP----------------------------VDPEPGDDE---------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3763|M.marinum_M TEGVGGAGGEGGAGGVAGD-----------------------------GG Rv3508|M.tuberculosis_H37Rv NGSGGAGGTGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGA MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 AGNGGDGGVGGNGGNGADN-------TTTAAAGTTGGAGGAGGAGGTGGT MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------GVGGVGGTG------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------QAGGIGGTG------------------- MMAR_3763|M.marinum_M KGADAAAFSGAAGGNGGHGGDNGAGGAGGTGGAGSTVGAHGADGFSPITG Rv3508|M.tuberculosis_H37Rv IGTGGTGGAVGSVGNAGIGGTGGTGGVGGAGGAGAA-------------- MUL_4367|M.ulcerans_Agy99 ----------GGVGAASLGGDGGHAGAGGAGGEGLS-------------- Mb3541|M.bovis_AF2122/97 GGAAGTG-TGGQQGNGGNGGNGGTGGKGGTGGAGMNSL------------ MSMEG_0868|M.smegmatis_MC2_155 -----------------TTAAGGNGGTGGTGRVIAE-------------- TH_3810|M.thermoresistible__bu -----------------RTTDNN--------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------------AAGAAGGAGGLG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ---------------AAGAAGQAGTAG----------------------- MMAR_3763|M.marinum_M GNGGDGGNGASGPAASAGVAGGAGGAGGDGGLYGNGGAGGDGGNGVAGGQ Rv3508|M.tuberculosis_H37Rv ---------AAAGSSATGGAGFAGGAGGEGGAGGNSGVGGTNGSG----- MUL_4367|M.ulcerans_Agy99 ---------GGFNTGAAGGIGGAGGAGGTGGDSG--GVGGVNGDG----- Mb3541|M.bovis_AF2122/97 ---------DPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNA----- MSMEG_0868|M.smegmatis_MC2_155 ---------GTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGN---- TH_3810|M.thermoresistible__bu -----------------ALDGGHGGN------GGNVGFFSLFNLG----- MAB_4284c|M.abscessus_ATCC_199 ---------------NAGLAGNAGLAG----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 --------------LAYSAVGEEDAESPTVVIEKLFLPEDSEPRRR---- Mflv_5091|M.gilvum_PYR-GCK -----------ETGTTGGAGGVGGQG-----------TAGGTGGVGGIGG Mvan_1264|M.vanbaalenii_PYR-1 -----------ETGVTGGVGGIGGQG-----------TEGGTGGVGGVGG MMAR_3763|M.marinum_M GADATAAGASGENGGDGGAGGMGGAGGMG-------GVLGGHGGAGGIGG Rv3508|M.tuberculosis_H37Rv -----------GAGGAGGKGGTGGAGGSGADNPTGAGFAGGAGGTGGAAG MUL_4367|M.ulcerans_Agy99 -----------GAGGGGGRGGDGGSSTS----TSGVGGAGGAGGNGGNAG Mb3541|M.bovis_AF2122/97 -----------GNGGDGGVGGNGGNGADN-TTTAAAGTTGGAGGAGGAGG MSMEG_0868|M.smegmatis_MC2_155 ----------NGAVSGTATGGRGGDG-----------IDGGTGGAGGMGE TH_3810|M.thermoresistible__bu -----------------GAGGWGGSG-----------VDG---------- MAB_4284c|M.abscessus_ATCC_199 -----------NAGLAGNAGLAGNAG-----------LAGNAGLAG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------PVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTP Mflv_5091|M.gilvum_PYR-GCK --AGSTG---------------AVGGVGGKGIQ----------------- Mvan_1264|M.vanbaalenii_PYR-1 --VGATG---------------GAGGVGGKGIQ----------------- MMAR_3763|M.marinum_M --VGATG---------------GSGGLGATGAEGVTGGNL---------- Rv3508|M.tuberculosis_H37Rv --AGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGLGLSG MUL_4367|M.ulcerans_Agy99 --FGVSAGGTG-----------GSAGDGGAGG------------------ Mb3541|M.bovis_AF2122/97 --TGGTGGAAGTG-TGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAA MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPT------- TH_3810|M.thermoresistible__bu -----------------------VDVVGGN-------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------GGQGLQGGKGGDGGAGGKGGDADSMGSAG---------- Mvan_1264|M.vanbaalenii_PYR-1 -----------GGQGLQGGQGGDGGTGGTGGDATSMGEAG---------- MMAR_3763|M.marinum_M -------HGGDGGNGGKGGIGGAGGDGGAGGKAQAAGFAD---------- Rv3508|M.tuberculosis_H37Rv FDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGATGA---------- MUL_4367|M.ulcerans_Agy99 ---------------GAGGVDGVGGASGNGGAAGAGGAGG---------- Mb3541|M.bovis_AF2122/97 QDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGADNTT MSMEG_0868|M.smegmatis_MC2_155 ----TGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGA---------- TH_3810|M.thermoresistible__bu ---------------------PDGGTPG---------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAGLAGNAGLAG---------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---------------NQHLIVPTEQAPAPPPVQASAPQPK---------- Mflv_5091|M.gilvum_PYR-GCK --ATGGKGGNGGNGGRGGLFGKGGN-----------AGNGADGGTGGAGG Mvan_1264|M.vanbaalenii_PYR-1 --ATGGKGGNGGNGGRGSLFGRGGN-----------AGNGGNGGTGGNGG MMAR_3763|M.marinum_M --GTEGAGGAGGEGGAGGVAGDGGKGADAAAFSGAAGGNGGHGGDNGAGG Rv3508|M.tuberculosis_H37Rv -AGLGDNGGVGGDGGAGGAAGNGGN---AGVGLTAKAGDGGAAGNGGNGG MUL_4367|M.ulcerans_Agy99 -SGIG----AGIDGGAGGAGGTGGA---AGF-----PGGGGTTGAWGTGG Mb3541|M.bovis_AF2122/97 TAAAGTTGGAGGAGGAGGTGGTGGA---AGTGTGGQQGNGGNGGNGGTGG MSMEG_0868|M.smegmatis_MC2_155 ---TGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSG TH_3810|M.thermoresistible__bu -------------------------------------AHG---------- MAB_4284c|M.abscessus_ATCC_199 ------NAGLAGNAGLAGNAGLAG-------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ---ISVPEPVAAPKPLSPPVAAPLP------------------------- Mflv_5091|M.gilvum_PYR-GCK AGGTGGTG------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 NGGTGGTG------------------------------------------ MMAR_3763|M.marinum_M AGGTGGAGSTVGAHGADGFSPTTGGNGGDGGSGGSGFQGVKGGAGGVGGD Rv3508|M.tuberculosis_H37Rv AGGAGGAGDNNFNGGQGGA--GGQGGQGGLGGASTTSINANGGAGGNGGT MUL_4367|M.ulcerans_Agy99 AGGAGGAG------------------------------------------ Mb3541|M.bovis_AF2122/97 KGGTGGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGGN MSMEG_0868|M.smegmatis_MC2_155 HGGAAQGGNG---------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ------------GAGGTGGTGGTGGIG----------------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------GNGGTGGTGGTGGIG----------------------- MMAR_3763|M.marinum_M GGL--------YGNGGTGGTGGTGGIGFNGSTTIGG-------------- Rv3508|M.tuberculosis_H37Rv GGKGGAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFG--GAAGKAGGGGNG MUL_4367|M.ulcerans_Agy99 ------------GAGDHGGVGVNPGDSGTAG------------------- Mb3541|M.bovis_AF2122/97 GGIGAAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGAGGAGGNG MSMEG_0868|M.smegmatis_MC2_155 ------------GNGGNGWVQAYDPNGPAGTTIDKGK------------- TH_3810|M.thermoresistible__bu --------------------ESHTP----GVYTDRQ-------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------GAGSTGGTGGTGGTGGTG----GTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 -------------------GAGSTGGTGGTGGTGGTG----GTGGTGGTG MMAR_3763|M.marinum_M ----------------GNGGDGHTGLTGGDGGAGGKGGALAGHGGDGGTG Rv3508|M.tuberculosis_H37Rv GRGGDGGDGASGLGLGLSGFDGGQGGQGGAGGSAGAG----GINGAGGAG MUL_4367|M.ulcerans_Agy99 -------------------WAGGAGGAGGAGGSAAFN----GVNGAGGAG Mb3541|M.bovis_AF2122/97 GKGGDGGAGVTSSTAGNSGGAGGSGGKGGDAGAGGAG----ATPGANGIA MSMEG_0868|M.smegmatis_MC2_155 ----------------------AAGGNGGDGGFNGTG------GATGGRG TH_3810|M.thermoresistible__bu ----------------------------GEDGEDGTG------TGIGGRG MAB_4284c|M.abscessus_ATCC_199 ----------------------NAGLAGNAGLAGNAG-----LAGNAGLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------------------AAPPPAAPPLPEAPP-----IPAAPPVV Mflv_5091|M.gilvum_PYR-GCK GTGGTGGT-GGKGGTG-------GTGGAGGTGGDGGTGGTGGTG------ Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGT-GGKGGTG-------GTGGDGGTGGTGGTGGTGGTG------ MMAR_3763|M.marinum_M GVGGTGGT-GGSGGTGTSGIFSSANGGDGGNGGDGGTGGTGGVGGLGGQA Rv3508|M.tuberculosis_H37Rv GNGGDGGD-GATGAAGLGDNGGVG--GDGGAGGAAGNGGNAGVGLT---- MUL_4367|M.ulcerans_Agy99 GNGGAGGG-GGAGASGIG-AGVAG--GDGGTGGTGG-------------- Mb3541|M.bovis_AF2122/97 GNGGDGGD-GAAGAVGISGATGAGDGGHGGTGGAGGNGGTGGAGGSG--- MSMEG_0868|M.smegmatis_MC2_155 GDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG TH_3810|M.thermoresistible__bu GNGG-----SSSGTHPMAE------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAGLAG------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVP--- Mflv_5091|M.gilvum_PYR-GCK ----------GTGGTGGTGGTGG-AGDG---------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----------GTGGTGGTGGTGG-AGDG---------------------- MMAR_3763|M.marinum_M QAAGFADGTQGVGGAGGVGGTGGNAGNGGHGAN----------------- Rv3508|M.tuberculosis_H37Rv -------AKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGGQGG MUL_4367|M.ulcerans_Agy99 --------AAGTGGAAGTGGTGGAAGAAGS-------------------- Mb3541|M.bovis_AF2122/97 ----IDGVGGGTGGTGGNGGNGAIGGAGGDAGGSGNSGGNGGTGGKGGNA MSMEG_0868|M.smegmatis_MC2_155 GVSEGEGGTGGHGGDGGRGGDGALGGNGGT-------------------- TH_3810|M.thermoresistible__bu ------------DGEHVKALDGRPGLDG---------------------- MAB_4284c|M.abscessus_ATCC_199 --------NAAVAGNAAVAGNAAVAGNAAVG------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 ----------QPPSPPQVGGTVPQSPPQ---------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3763|M.marinum_M -ADVGSGKAGGNGGDGGDPGVGGIGGQGGAGSIAGVEGAAGVAPTSGGNG Rv3508|M.tuberculosis_H37Rv LGGASTTSINANGGAGGNGGTGGKGGAGGAGTLGVGGSGGTGGDGGDAGS MUL_4367|M.ulcerans_Agy99 ---------------AGDGGAGGAGGAGDDGSAGVVS--------GDPG- Mb3541|M.bovis_AF2122/97 GAGGAAGSNGGTVGANGTGGDGGNGGAAGAATAGSNGGAGTGSAGGNGGT MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3763|M.marinum_M GDGGNGASGATGVNGGAGGSGGDGGLYGNGGDGGDGGNGGKGQVGSTGPV Rv3508|M.tuberculosis_H37Rv GGGGGFG-----GAAGKAGGGGNGGVGGDGGEGASGLGLGLSGFDGGQGG MUL_4367|M.ulcerans_Agy99 -------------TAGKAGGAG---------------------------G Mb3541|M.bovis_AF2122/97 GGRGGSGGAGGDGIGGVGGGKGGNGADGEVGGAGGAGGSGPNTSPGGNGG MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGGQGGQGGQGGTG--------------------------- Mvan_1264|M.vanbaalenii_PYR-1 LGGTGGTGGTGGFGGQGGQGGTG--------------------------- MMAR_3763|M.marinum_M AGSAGGTGGTGGTGGQGGAGGSGG-------------------------- Rv3508|M.tuberculosis_H37Rv QGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGDGGQGGIGG MUL_4367|M.ulcerans_Agy99 AGGVGGNGVAGGVNGSGGAGGAG--------------------------- Mb3541|M.bovis_AF2122/97 QGGQGGSGGAGGAAGAGGAGGGAN-------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGVGLGNGGKGGNGGNGGNGGTYV-------------------------- TH_3810|M.thermoresistible__bu -----GNGSHGGNGGHGGRGG----------------------------- MAB_4284c|M.abscessus_ATCC_199 --GVLNTGVSGAIGGSSHVGGAIN-------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 HQTPPGEGTPPKPDGPGNYGGGHVP------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------GTGGQGGLGGGGGTGGQGGTG- Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------GTGGQGGLGGVGGTGGTGGTG- MMAR_3763|M.marinum_M -------------------------ALAGHGGDGGSGGDGGTGGTGGTGR Rv3508|M.tuberculosis_H37Rv DGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGD MUL_4367|M.ulcerans_Agy99 -------------------------------------GAGGTGGAGASGV Mb3541|M.bovis_AF2122/97 --GTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGAGGTGGAGGDGV MSMEG_0868|M.smegmatis_MC2_155 --------------------------------DPSHTGAGGNGGNGGAGR TH_3810|M.thermoresistible__bu -----------------------------------FLGIGGSGGWG---- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------ESLGGSGSVGGST- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----------------------------------TPGAGGSGGSGGGHV Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------GTGGQGGTG Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------GTGGQGGTG MMAR_3763|M.marinum_M NGANGITG----------------------------ADIDGGSGGKGGNG Rv3508|M.tuberculosis_H37Rv PSIDGGQGGAGGHGGQGGKGG---------LNSTGLASAASGDGGNGGAG MUL_4367|M.ulcerans_Agy99 P--------------------------------------ASVDGGDGGAG Mb3541|M.bovis_AF2122/97 GGAGGGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGGAAGDGGQGGQG MSMEG_0868|M.smegmatis_MC2_155 IRVNNGTA---------------------------TGTATGGNGGNGGNG TH_3810|M.thermoresistible__bu -----------------------------------------GHGGNGGDT MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------AVGGGAHT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 P-----------------------------------------TPGAGGSG Mflv_5091|M.gilvum_PYR-GCK GTGG-----------TGGTGG----------------TGGAGGDGGLGGL Mvan_1264|M.vanbaalenii_PYR-1 GTGG-----------TGGTGG----------------TGGAGGDGGLGGL MMAR_3763|M.marinum_M GTGG-----------AGGAGGQGGQAQAAGYSDGTQGVGGAGGDGGTAGI Rv3508|M.tuberculosis_H37Rv GAGGNGGDGDGFIGGSGGTGGTGGDA----GVGGLANTGGTAGNAGIGGA MUL_4367|M.ulcerans_Agy99 GAGG-----------AAGTGGSG----------------GSAGNTGAGGA Mb3541|M.bovis_AF2122/97 GAGG-GAGGQGGAGGAGGTGGNGGN-----ITGGTAGTAGAAGNGGAAGK MSMEG_0868|M.smegmatis_MC2_155 DADG----------HRGGKGGDGGEA-----LIRATVIGSNASGTATGGD TH_3810|M.thermoresistible__bu DADG----------GNGGDGGNGG----------------------SAGR MAB_4284c|M.abscessus_ATCC_199 GVGG------------GVSTGVG--------------VGSHVGGGISESL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GSGG-----------------------------------GHVPTPGTGGP Mflv_5091|M.gilvum_PYR-GCK GGFGGSGG------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGG------------------------------------------ MMAR_3763|M.marinum_M GGDGGDGANAVAGSGERGGDGGHGGDPGNAGAGGQAGAGPTSGGNGKAGS Rv3508|M.tuberculosis_H37Rv GGRGGDGGAGDSGALS----------QDGNGFAGGQGGQGGVGGNAGAGG MUL_4367|M.ulcerans_Agy99 GGAGGAGGSAASTGVN----------GDG--------------------- Mb3541|M.bovis_AF2122/97 GGAGGQGGTGGGTGGQGG--------AGGDGGAGGTGGDRTVGGGTVPAG MSMEG_0868|M.smegmatis_MC2_155 GGNGGTLGATNGTGGAAT------------IVAYNVVQANPQASGTATDG TH_3810|M.thermoresistible__bu GGTGGLRGVF---------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVGG------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGTGGSGG------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK ---TGGQGGLGGPGGS----------TGGAGGAGGQAGTAGKGGLFGGSG Mvan_1264|M.vanbaalenii_PYR-1 ---TGGQGGQGGPGGS----------TGGAGGAGGQAGVAGKGGLFGGSG MMAR_3763|M.marinum_M GVTTGGNGGDGGDGGSG-----AIGVKGGAGGAGGDGGLYGNGGNGGDGG Rv3508|M.tuberculosis_H37Rv INGAGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAG MUL_4367|M.ulcerans_Agy99 --GAGGAGGVGGLGGDS-------AATAGGGGAGGDGGKGGAGGAGVNGV Mb3541|M.bovis_AF2122/97 SGGQGGNAGGGGAGGQG-------GADGGSGGDGGDAGTGGNGGNGGNRN MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG TH_3810|M.thermoresistible__bu ----GINGGNGR------------------------------AGLGGRGX MAB_4284c|M.abscessus_ATCC_199 ----GAHTGVGGGVSTG-------------VGVGSHVGGGISESLGGSGS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------GHVPTPGAGTPGGSGGGHL Mflv_5091|M.gilvum_PYR-GCK SAGK------------------AGATG----------AAGASGGKGAQG- Mvan_1264|M.vanbaalenii_PYR-1 SAGT------------------AGVTG----------ASGASGGKGAQG- MMAR_3763|M.marinum_M TGGKGTVGDSGATLSADGDRGGAGATGGVGGAGGDGGAKGGNGGLGGSG- Rv3508|M.tuberculosis_H37Rv FGAG---------------VPGDGGIG----------GTGGAGGAGGAG- MUL_4367|M.ulcerans_Agy99 GG-------------------GDGGKG----------GTGGAGGAGGAG- Mb3541|M.bovis_AF2122/97 SGNG---------------TGGAGGNG----------GGGANGGAGGAGG MSMEG_0868|M.smegmatis_MC2_155 DGVVNT-------------TANAANPGSA--------TGTATGGDGGKAT TH_3810|M.thermoresistible__bu X-------------------------------------------XXGGGV MAB_4284c|M.abscessus_ATCC_199 VGGS-----------------------------------TAVGGGAHTGV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 PFPG------------------------------------AGSTPGGSGG Mflv_5091|M.gilvum_PYR-GCK ATGAQGATGAQG-------------ATGATGAAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 ATGAQGATGAQG-------------ATGATGASG---------------- MMAR_3763|M.marinum_M GTGGMGGTGGDG-------------AHGADMASGSGANGGYGGYGGFGGV Rv3508|M.tuberculosis_H37Rv ADGDPSIDGGQG---------------GAGGHGGQGGKGGLNSTGLASAA MUL_4367|M.ulcerans_Agy99 SDGIIPSNGGLG---------------GNGGNGGNGGQ-----------A Mb3541|M.bovis_AF2122/97 SGGGTGGNGGAGGDAGDAGNGGNGNGTGNGGNGGNGGIAGMGGNGGAGTG MSMEG_0868|M.smegmatis_MC2_155 GTASQGGNGGPS--------------WVQSGYGSTLGG----------NA TH_3810|M.thermoresistible__bu GAAVRSGNG------------------VFSGGG----------------- MAB_4284c|M.abscessus_ATCC_199 GGGVNTGVGVGS-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GHLPTPGAGTPG-------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -KAGATGAAG----------------------AAGAAGSAGTTGAQGSAG Mvan_1264|M.vanbaalenii_PYR-1 -AQGSAGSAG----------------------SAGVAGSAGTTGAQGSAG MMAR_3763|M.marinum_M GGAGGTGGVGGQAHAAGF---------TDGATGAGGDGGQGGTGGLGAWG Rv3508|M.tuberculosis_H37Rv SGDGGNGGAGGAGGNG--------GDGDGFIGGSGGTGGTGGDAGVGGLA MUL_4367|M.ulcerans_Agy99 FGDG--------------------------VGGAGGIGGKGGNAAIGTIV Mb3541|M.bovis_AF2122/97 SGNGGNGGSGGNGGNAGMGGNSGTGSGDGGAGGNGGAAGTGGTGGDGGLT MSMEG_0868|M.smegmatis_MC2_155 TGTATAGKGG--------------------EASNGGVAGNGGNALVMAAG TH_3810|M.thermoresistible__bu -GTPSAGFGV--------------------PTT---IQFPAGSCTSRAVS MAB_4284c|M.abscessus_ATCC_199 ------------------------------HVGGGISESLGGSGSVGGST MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------GGLGGFGGGHAPAPGGGLG Mflv_5091|M.gilvum_PYR-GCK TNGANGANGSQ--------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 TNGANGANGSQ--------------------------------------- MMAR_3763|M.marinum_M GNGGDGADGSISGPPQNGGKGGDGGGGGP--------------------- Rv3508|M.tuberculosis_H37Rv NTGGTAGNAGIGGAGGRGGDGGAGDSGAL----SQDGNGFAGGQGGQGGV MUL_4367|M.ulcerans_Agy99 ING----------------------------------------------- Mb3541|M.bovis_AF2122/97 GTGGTGGSGGTGGDGGNGGNGGNGADNTANMTAQAGGDGGNGGDGGFGGG MSMEG_0868|M.smegmatis_MC2_155 TTGVATGNTATG-------------------------------------- TH_3810|M.thermoresistible__bu REGIMPSSRAAS-------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVGGGAHTSAIN-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 GGGGHAPAPGGG-------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----GAAGKAGATGTTGATGAAGEDGDA---------------------- Mvan_1264|M.vanbaalenii_PYR-1 ----GAAGKAGATGTTGATGAAGDAGDP---------------------- MMAR_3763|M.marinum_M ---GGLGGQGGLSGDGSSTGAAGELGTF---------------------- Rv3508|M.tuberculosis_H37Rv GGNAGAGGINGAGGTGGTGGAGGDGQNGTTG------------------- MUL_4367|M.ulcerans_Agy99 -------GVGGAGGSGGLGGATEDG------------------------- Mb3541|M.bovis_AF2122/97 AGAGGGGLTAGANGTGGQGGAGGDGGNGAIGGHGPLTDDPGGNGGTGGNG MSMEG_0868|M.smegmatis_MC2_155 -------GDGGAATTAGATGGAGGFSNIAAIHG----------------- TH_3810|M.thermoresistible__bu -------ARAGAACASSTSRSRRSFCCSRA-------------------- MAB_4284c|M.abscessus_ATCC_199 ------DALGGSGSVGGSTAVGGGAHTSAIN------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -----LGGFGGGHSGGGLGGLGGGHK------------------------ Mflv_5091|M.gilvum_PYR-GCK -------------------------------------GSGGSGINGGAG- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------GSEAVDINGGAG- MMAR_3763|M.marinum_M -------------------------------------GNGGSGGNGGIGG Rv3508|M.tuberculosis_H37Rv -VASEGGAGGQGGDGGQGGIGGAGGNAGFGAGVPGDGGIGGTGGAGGAGG MUL_4367|M.ulcerans_Agy99 --------------------------------------VGGVGCAGGAG- Mb3541|M.bovis_AF2122/97 GTGGTGGAGIGSLGGGTGGDGGNGGTGGNGGTGGEGGEVGGAGGTGGAAG MSMEG_0868|M.smegmatis_MC2_155 --------------------------AITDSTAISGHGGAGNGGNGGKGA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------ESMNSSINASHS- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------------------GAGGAG------------GEGGEGGDGGK Mvan_1264|M.vanbaalenii_PYR-1 ---------------------GAGGAG------------GEGGEGGAGGA MMAR_3763|M.marinum_M NATGFNAP-------------GTGGAG------------GNGGNGAFGGS Rv3508|M.tuberculosis_H37Rv AGADGDPS-IDGGQGGAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGA MUL_4367|M.ulcerans_Agy99 ---------------------GNGGRGDMLFT-----------VGGSGGT Mb3541|M.bovis_AF2122/97 NGGDGGTGGTGGGDGGAGGTGGTGGTGGLGDPRVGGSG-GDGGTGGSGGA MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYD-----------PAGPVGSKIANSSAVAGNGGDGGVNGTGGAS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------SSMNESFGSS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGAGAEGG--------AGGGGGAGGSGAGGAGGAGGSGG----------- Mvan_1264|M.vanbaalenii_PYR-1 GGDGSEGG--------AGGSGGAGGSGTGGAGGAGGSGG----------- MMAR_3763|M.marinum_M GGTGGRGGSSSVGTGGAGGDGGDGGMGFGGIGGGGGTGGQGGSGVDAQGI Rv3508|M.tuberculosis_H37Rv GGNGGAGGLG-------GGGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGS MUL_4367|M.ulcerans_Agy99 GGDGGGGGSA-------SGSGTGGSGGTGGVGGIGGDGKLG--------- Mb3541|M.bovis_AF2122/97 AGNGGNGGNAG-----AGGNGNGGTGGAGGIGGTGGNGGDAEPGVPPGAG MSMEG_0868|M.smegmatis_MC2_155 GGDGGNGGNTS--VWKSGGQTADGEHNTGGNGGNGGDGSEPGPG------ TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 MGSHGAAGTG----FEAQGHAQGHASETAHTTLPGAEHH----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ------------------------------------------------SG Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------------SG MMAR_3763|M.marinum_M GGAGNGGVGGNGGDGGDGWDAPGGQGGKGGQGGNGGDGSPPVPPFGGSSG Rv3508|M.tuberculosis_H37Rv GTEGTGGDGGDAGAGGNGGSATGV-----------------------GNG MUL_4367|M.ulcerans_Agy99 -------------------------------------------------- Mb3541|M.bovis_AF2122/97 GAGGAGTTGGKGGTGGNGSGTGSG-----------------------GTG MSMEG_0868|M.smegmatis_MC2_155 ------------------------------------------------GN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GSGGSGGSGGAAGD--SDD------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GSGGAGGSGGAAGD--SD-------------------------------- MMAR_3763|M.marinum_M GTGGTGGTGGAGGDRFVDTELVG--IGGAGHGGVTGGGPTGPALVDGGTG Rv3508|M.tuberculosis_H37Rv GNGGDGGNGGDGGNGAPGGFG-----GGAGAGGLGGSGAGGGTDGDDGNG MUL_4367|M.ulcerans_Agy99 GFGGDGGDGGDGGFGVIGGQG-----GGGGFGGLGGTGAGG-APSDKGIN Mb3541|M.bovis_AF2122/97 GDGGTGGGGGNGGTGWNGGKGDTGSGGGAGDGGKAPAGGTGGAGGDGGAG MSMEG_0868|M.smegmatis_MC2_155 GAGGAGGNGGTGGTT----------AGGSGNGGNGGNGGNGGADGTPGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------- Mvan_1264|M.vanbaalenii_PYR-1 ----------- MMAR_3763|M.marinum_M GAGGSGGTGAH Rv3508|M.tuberculosis_H37Rv GSPGTDGS--- MUL_4367|M.ulcerans_Agy99 GEPGNPG---- Mb3541|M.bovis_AF2122/97 GKGGSGGV--- MSMEG_0868|M.smegmatis_MC2_155 GTTGANNP--- TH_3810|M.thermoresistible__bu ----------- MAB_4284c|M.abscessus_ATCC_199 ----------- MLBr_01183|M.leprae_Br4923 ----------- MAV_4827|M.avium_104 -----------