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VSLVSVVPEWVAAAATDVAGIGSVVGAANAAAAGATTSVAAAAGDEVSVAIAALFGGFGREYQVVCGQWA EFERRFAGALGAGAGAYAGAEAAAVGMLSPLGVVEQGVWGAVNGPAVALWGRPLVGDGADGVAGTGQAGG AGGLLWGNGGSGGSGGVGQSGGAGGSAGLIGRGGAGGAGGFSGGSGAGGAGGVGGNGGWLWGAGGDGGAG GVGAVSGGVGGGAGRAWLWGAGGAGGAGGQGVGLDGGAGGGGGQGGLVYGGGGDGGTGGVGAVSGGVGGG AGRAWLWGAGGAGGAGGQGVGLDGGAGGGGGQGGLVYGGGGDGGAGGVGGEVGGGGVGGTGGAGGAAGLI GRGGDGGGGGAGDGGSTGGAGQTGGDGGRAGDGGVGGRGGWLAGAGGDGGAGGVGGVGGAGGGGADGLVL GGDGGDGGDGGTGGAGGSGGAGGAGGLISLFGGQGAGGAGGAGGAGGLAGDGGVGAAGTFAGGGSGTGGA GGDGGTPGVGGAGGAGGAGSVAGAHGSEGARPLSGDGGSGGRGADSTVAGGIAGDGGVGGNGGVFGNGGS GGAGGTGVAGQRGVSADTAGGSGTAGEDGGVGGDGGAGGLGGALAGHGGDGGAGGIGGAGGDGGSGAAGA AGDRGIIAHLDGGRGGDGGSGADGGAGGSGGNGGAGGQAQAAGYADGVRGAGGSGGAGGAGGLAGAGGAG GDAYTTGGGAGGDGGHGGDTGAGGAGGSGGVGSSTGLTGLSGHSPTSGGDGGDGGAGGRGAIDIAGGTGG AGGDGGTYGDGGDGGAGGDGVTGSQGLTATTPGGSGTNGGAGSAGGAGGSGGLGGTLAGHGGDGGAGGAG GDGGFGGSGATGSSGDQGSAANPNGGRGGDGGSGADGGAGGTGGDGGAGGQAQAAGYADGTRGAGGNGGA GGSGGLAGDGGRGGDGAVGFGGAGGDGGHGGNTGAGGVGGKGGVGSTTGLTGLGGHSPTNGGNGGAGGDG GKGAVDIAGGVGGAGGNGGAYGNGGAGGDGGDGVNGTRGLTAIAPGGSGTDGGAGSAGGAGGYGGNGGAL AGDGGDGGDGGNGGSGGDGGSGANGGAGTNGTTTGIPDGGRGGDGGHGGHGGDGGAGGHGGVAGKAQAAG YTDGTHGAGGVGGNGGAGGLAGDGGRGGNGAATASGNGGDGGNGGDPGVGGAGGKGGIGETIGLSGLGGY NPTSGGNGGDGGDGGSGSDGDFNHLAGSDGGNGGHGGSGGAFGNGGNGGDGGTGGDGSRAFQPEIAGGAA GHGGAGGAGGDGGYLAGNGGTGGTGGAGGAGGTGAAGEPQFENGQNGGAGGIGRAGGAGGDGGNGGHAHA AGFQNGAGGAGGDGGQGGTGGGGGFGGDGKAGYNQRAGGDGGAGGDGGFGGTGGTGGLNGDGTTRATSGA NGIRGDGGSGGTGGNGLGGRTENGDGGHGGKGGVGGYGSVGGVGGSGGHGGNGGQSGTPRFGGHGGDGGA GGAGVVTGGTGGTGGAGGNGLDGTAKAAGGNGGNGGVGGAGGVAGGAGGAGGAGGAGGNGPGGLFGPDGG SGGSGGNGGAGGSGGTTGTGGAGGGGGNGGNGGTGFSTNNVASGGMGGGGGKGGGGGDGLIGGAGGGGGD GGNGAAGLTSGGNGGAGGAGGAGGAGRTTSGDGGSGGNGGTGGEGGGDILVAPVVAGTGGAGGEGGAGGY SNTVGGVAGNGGAGGSGGTGGTLAAHKVVYTSSGRGGVGGTGGVGGSSTYGTGGVGGTGGTGGMGGAADL NNYAAASGAGGTGGIGGAGVTGGDGGRGGTGGRSAYIGIPGTGGIGGIGGLGTAGLGGYGGDGGTGGSGH GVAGGYGGAGGRGGTSTVDGQRIPGVNGDSGQPPPPGYTGPPGAGGSGGAPGGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1829 | - | - | 100% (1874) | PE-PGRS family protein |
| M. marinum M | MMAR_0806 | - | 0.0 | 70.72% (2114) | PE-PGRS family protein |
| M. marinum M | MMAR_3763 | - | 0.0 | 57.07% (1873) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3541 | PE_PGRS55 | 0.0 | 49.51% (2048) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 0.0 | 47.20% (875) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3508 | PE_PGRS54 | 0.0 | 48.82% (2038) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 2e-11 | 46.07% (89) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 5e-49 | 34.98% (446) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 4e-26 | 43.01% (193) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-171 | 40.45% (1100) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-47 | 41.67% (324) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4367 | - | 0.0 | 50.86% (1166) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-178 | 46.94% (818) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP
Rv3508|M.tuberculosis_H37Rv -MSFVLIAPEFVTAAAGDLTNLGSSISAANASAASATTQVLAAGADEVSA
MUL_4367|M.ulcerans_Agy99 -MSFVSVGPGLLEAAARDLAGLGAGLREANLAAAGATVGVLPAAGDEVSA
Mb3541|M.bovis_AF2122/97 -MSFVLISPEVVSAAAGDLANVGSTISAANKAAAAATTQVLAAGADEVSA
MMAR_1829|M.marinum_M -MSLVSVVPEWVAAAATDVAGIGSVVGAANAAAAGATTSVAAAAGDEVSV
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVA
MAV_4827|M.avium_104 -MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPD
MLBr_01556|M.leprae_Br4923 -----MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVAR
Mflv_5091|M.gilvum_PYR-GCK --MVTFGGGA------TPTPTSLGAAAVDLSGTSCG--------------
Mvan_1264|M.vanbaalenii_PYR-1 WYVVSFGGSG------APTPNNLAASLVDLSGTSCG--------------
Rv3508|M.tuberculosis_H37Rv RIAALFGGFGLEYQAISAQVAAYHQRFVQALSTGAGAYASAEAA------
MUL_4367|M.ulcerans_Agy99 AIAELFGGFGREYQAMGARVALLHDDFVRALTAGGSAYGQAEALNM---W
Mb3541|M.bovis_AF2122/97 RIAALFGMYGLEYQAISAQVAAYHQQFVQTLRTGAASYMLAEATN-----
MMAR_1829|M.marinum_M AIAALFGGFGREYQVVCGQWAEFERRFAGALGAGAGAYAGAEAAAVGMLS
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTN------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPD--------------
MAV_4827|M.avium_104 RVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALR-------------
MLBr_01556|M.leprae_Br4923 RLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQT--------------
Mflv_5091|M.gilvum_PYR-GCK ------------------------LICNGQD------GTGQNGGIL-FGN
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------LICNGQD------GTGQNGGIL-FGN
Rv3508|M.tuberculosis_H37Rv ---AAEQIVLGVINAPTQALLGRPLIGDGAN-ATTPGGAGGAGGLL-FGN
MUL_4367|M.ulcerans_Agy99 PLQELEQQALGVVNAPSMALFGRPSIGNGVDGVAGTGQAGGAGGIL-WGN
Mb3541|M.bovis_AF2122/97 ----VEQNLLNLINAPTQTLLGRPLIGDGAN-ATTPGGAGGDGGLL-FGS
MMAR_1829|M.marinum_M PLGVVEQGVWGAVNGPAVALWGRPLVGDGADGVAGTGQAGGAGGLL-WGN
MSMEG_0868|M.smegmatis_MC2_155 ---TTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------GPSILSPSLLSPRDNDFLSHND
MAV_4827|M.avium_104 ----------------------DALAARRIDNVMLVSAFLAAAALAQNVG
MLBr_01556|M.leprae_Br4923 -------------------------LDRALDKAVAGNGATTAAPVQVDHS
Mflv_5091|M.gilvum_PYR-GCK GGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNG-----------------
Mvan_1264|M.vanbaalenii_PYR-1 GGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNG-----------------
Rv3508|M.tuberculosis_H37Rv GGAGA-AGAPGQAGGPGGPAGLWGNGGPGGAGGSGGGTGGAGGAGGWLFG
MUL_4367|M.ulcerans_Agy99 GGNGG-LGAAGANGGAGGSAGLIGTGGVGGAGG-----------------
Mb3541|M.bovis_AF2122/97 GGNGA-PGAPGQAGGAGGSAGLLGNGGSGGAGGTG-APGGNGGNAGWLYG
MMAR_1829|M.marinum_M GGSGG-SGGVGQSGGAGGSAGLIGRGGAGGAGGFS---------------
MSMEG_0868|M.smegmatis_MC2_155 LGTTLIPNAPTEPADMPGVWAVMAWARRQPMYS-----------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TDFASHNPIASGNQVMSPSGNVDSFNRGP---------------------
MAV_4827|M.avium_104 GAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYK---------------
MLBr_01556|M.leprae_Br4923 AAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVP----------------
Mflv_5091|M.gilvum_PYR-GCK ---------LGGGNGGNGGNAGAFA-------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------LGSGDGGNGGDAGLFS-------------------------
Rv3508|M.tuberculosis_H37Rv VGGAGGVGGAGGGTGGAGGPGGLIWGGGGAGGVGGAGGGTGGAGGRAELL
MUL_4367|M.ulcerans_Agy99 VGAAG----MTGGSGGAGGGGGWLWGAGGSGGAAGAGG------------
Mb3541|M.bovis_AF2122/97 RGGVGGAGGIGGGTGGAGG-HAWLFGHGGTGGIGGGPGGNGG--------
MMAR_1829|M.marinum_M -GGSG-----AGGAGGVGGNGGWLWGAGGDGGAGGVGAVSGG--------
MSMEG_0868|M.smegmatis_MC2_155 ----------DPAMRTTVNPQAQLPVPTVASAVLDPTQIVN---------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv FGAGGAGGAGTDGGPGATGGTGGHGGVGGDGGWLAPGGAGGAGGQ---GG
MUL_4367|M.ulcerans_Agy99 --------------------------SGGSGGWLWG--------------
Mb3541|M.bovis_AF2122/97 ------WLLGNGGHGGAGGIGGGSGGAGGNGGWLLGNGGIGGAG----GT
MMAR_1829|M.marinum_M ------------------------VGGGAGRAWLWGAGGAGGAGGQGVGL
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------WLIYQP------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------------------------------LFGNGGNGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------LFGRGGNGG
Rv3508|M.tuberculosis_H37Rv AGGAGSDGGALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGG
MUL_4367|M.ulcerans_Agy99 ---------------NAGQTAGAG-----------------VGGAGGAGG
Mb3541|M.bovis_AF2122/97 GGGAGGTGGNAAWLLGGGGTGGAGGIGGGNGGHGGNGG--WLLGNGGNGG
MMAR_1829|M.marinum_M DGGAGGGGGQGGLVYGGGGDGGTGGVGAVSGGVGGGAGRAWLWGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 ------------LHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNG-ING
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------LLDLSFGDL
MAV_4827|M.avium_104 ----------------------------------------QQIRAESYGD
MLBr_01556|M.leprae_Br4923 -----------------------------------------LPGQQGTPA
Mflv_5091|M.gilvum_PYR-GCK NGGVGVVGATG---------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 NGGVGIAGATG---------------------------------------
Rv3508|M.tuberculosis_H37Rv TGGAGGDGVLGGVGGTGGKGGVGGVAGLGGAGGAAGQLFSAGGAAGAVGV
MUL_4367|M.ulcerans_Agy99 AGDAGDQGVSG---------------------------------------
Mb3541|M.bovis_AF2122/97 LGGDGDGGTGGGHGGNGGNPGWLLGTAGGGGNGGAGSTGTAGGGSGGTG-
MMAR_1829|M.marinum_M AGGQG-VGLDGGAGGGGGQGGLVYGGGGDGGAGGVG------GEVGGGGV
MSMEG_0868|M.smegmatis_MC2_155 TADNPNGGTGG---------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 QFGNRDTTAIG---------------------------------------
MAV_4827|M.avium_104 AAGQLSAMVAG---------------------------------------
MLBr_01556|M.leprae_Br4923 APHPGHPGMPTG--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------------AVGAPGVAGATGATGVTSGVVGGNGEDAVGYG
Mvan_1264|M.vanbaalenii_PYR-1 ------------------AVGAPGVAGATGATGVTSNVTGGNGADAVGYG
Rv3508|M.tuberculosis_H37Rv GGTGGQGGAGGAGAAGADAPASTGLTGGTGFAGG-AGGVGGQGGNAIAGG
MUL_4367|M.ulcerans_Agy99 --------------------VAPGEAGAVGFAGG-AGGAGGAGGNGVGGG
Mb3541|M.bovis_AF2122/97 GDGGTGGRGGLLMGAGAGGHGGTGGAGGAGVDGGGAGGAGGAGGNGGAGG
MMAR_1829|M.marinum_M GGTGGAGGAAGLIGRGGDGGGGGAGDGGSTGGAGQTGGDGGRAGDGGVGG
MSMEG_0868|M.smegmatis_MC2_155 ---------------LLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------DGAVAVGGSNSGPIASGQGSTAVNG
MAV_4827|M.avium_104 ------------------LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTF
MLBr_01556|M.leprae_Br4923 --------------------PHPGPAPKPGGRPPRVGNNPFSSAQSVARP
Mflv_5091|M.gilvum_PYR-GCK ------ATGAAGAAG----AAGAAGAAGAVGSAG----AAGEAGETGTWG
Mvan_1264|M.vanbaalenii_PYR-1 ------ATGAAGAAG----AAGAAGKAGAVGSAG----TAGSAGAPGVWG
Rv3508|M.tuberculosis_H37Rv ----INGSGGAGGTG----GQGGAGGMGGSGADNASG-IGADGGAGGTGG
MUL_4367|M.ulcerans_Agy99 ----VNGAGGAGGAG----GVGGGGGAGASGVG-----AGVAGGDGGTGG
Mb3541|M.bovis_AF2122/97 QAALLFGRGGTGGAG----GYGGDGGGGGDGFDGTMAGLGGTGGSGGTGG
MMAR_1829|M.marinum_M RGGWLAGAGGDGGAG----GVGGVGGAGGGGADG--LVLGGDGGDGGDGG
MSMEG_0868|M.smegmatis_MC2_155 VG-WAGLDGGNGGSGGLLMGIGGAGGAGGVGADG--TSAHVDGGTGGTGG
TH_3810|M.thermoresistible__bu -----------------------------------------VDGDGGSGG
MAB_4284c|M.abscessus_ATCC_199 DVRDSNIINADHGSN-----------------------VGVDQSQTRVGG
MAV_4827|M.avium_104 LDVSVAEEPETALARG----------------------AALAAANAPLFA
MLBr_01556|M.leprae_Br4923 IPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGG
.
Mflv_5091|M.gilvum_PYR-GCK NAG-LPGKAGDAG---------------GAGAVGAAGAAGTVGTAGATGG
Mvan_1264|M.vanbaalenii_PYR-1 NAG-LPGAAGAAG---------------GAGAIGTAGVAGAAGTAGATGG
Rv3508|M.tuberculosis_H37Rv NAG-AGGAGGAAGTGG-TGGVVGAAGKAGIGGTGGQGGAGGAGSAGTDAT
MUL_4367|M.ulcerans_Agy99 AGG-AAGVGGAAGTGG-TG------GAAGVAGTGGDGGDGGAGGAGSDAS
Mb3541|M.bovis_AF2122/97 DGG-APGNGGAGGAGQ-LLSHSGVAGASGKGGAGGTGGNGGAGSAGADAP
MMAR_1829|M.marinum_M TGG-AGGSGGAGGAGG-LISLFGGQGAGGAGGAGGAGGLAGDGGVGAAGT
MSMEG_0868|M.smegmatis_MC2_155 TGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLI
TH_3810|M.thermoresistible__bu RTG--------------------------LFSKLSRGGDGGDG-------
MAB_4284c|M.abscessus_ATCC_199 DYT----------------------------NVSGHGSADIDKSVTVVDD
MAV_4827|M.avium_104 SST----------------------AALAYAQDPGTGAVDQYSLPDYLYV
MLBr_01556|M.leprae_Br4923 RSD----------------------AGGGNYRGGGVGALPGGGSGGFRGR
*
Mflv_5091|M.gilvum_PYR-GCK TGTGANG------GAGGVGGVGG-TGAAG-AAGGAGGLGETGTT--GGAG
Mvan_1264|M.vanbaalenii_PYR-1 TGVGGNG------GAGQAGGIGG-TGAAG-AAGQAGTAGETGVT--GGVG
Rv3508|M.tuberculosis_H37Rv A-TGATGGTGFSGGAGGAGGAGG-NTGVG-GTNGSGGQGGTGGA--GGAG
MUL_4367|M.ulcerans_Agy99 L-AGQAG---FAGGSGGAGGVGG-SAGAG-GVNGSGGDGGAGAA--GGAG
Mb3541|M.bovis_AF2122/97 AGSGAMGSTGFAGGAGGDGGNGG-GSGASQGNGGNGGNGGTGGK--GGTG
MMAR_1829|M.marinum_M FAGGGSG-TGGAGGDGGTPGVGG-AGGAGGAGSVAGAHGSEGARPLSGDG
MSMEG_0868|M.smegmatis_MC2_155 AGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANG
TH_3810|M.thermoresistible__bu -------------GLGGNGGHGG----------GTGIISLLS--------
MAB_4284c|M.abscessus_ATCC_199 HSQRNTTNINDSFNTDRSTNIGS-------GNTTNTEIGSHNQAN-----
MAV_4827|M.avium_104 PVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSG
MLBr_01556|M.leprae_Br4923 PGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAP-
. .
Mflv_5091|M.gilvum_PYR-GCK G-------------VGGQGTAGGTGGVG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 G-------------IGGQGTEGGTGGVG----------------------
Rv3508|M.tuberculosis_H37Rv GAGGVGAD--NPTGIGGTGGTGGKGGAGGAGGQGGSSGAGGTNGSGGAGG
MUL_4367|M.ulcerans_Agy99 GASAT---------VAGSGGVGGDGGAGGAAG------------------
Mb3541|M.bovis_AF2122/97 GAGMNSLDPLLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGG
MMAR_1829|M.marinum_M GSGGRGADSTVAGGIAGDGGVGGNGGVFGNGGSGGAGGTGVAGQRGVSAD
MSMEG_0868|M.smegmatis_MC2_155 GTVDG-------HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGST
TH_3810|M.thermoresistible__bu --------------LAGNGGNGGN--------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------IGTSTSAGGSAAVG----------------------
MAV_4827|M.avium_104 LAVVG---------ISAVLALEIALAIG----------------------
MLBr_01556|M.leprae_Br4923 -------------VVGGVRLPHGNGETIR---------------------
.
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv TGGQGGAGGAGGAGADNPTGIGGAGGTGGTGGAAGAGGAGGAIGTGGTGG
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mb3541|M.bovis_AF2122/97 VGGNGGNGADN-------TTTAAAGTTGGAGGAGGAGGTGGTGGAAGTG-
MMAR_1829|M.marinum_M TAGGSGTAGED----------------GGVGGDGGAGGLGG--------A
MSMEG_0868|M.smegmatis_MC2_155 AEGTATGGD-----------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------GIGGAGSTGAVGGVGGKGIQ----------GGQGLQGGKGGD
Mvan_1264|M.vanbaalenii_PYR-1 --------GVGGVGATGGAGGVGGKGIQ----------GGQGLQGGQGGD
Rv3508|M.tuberculosis_H37Rv AVGSVGNAGIGGTGGTGGVGGAGGAGAA--AAAGSSATGGAGFAGGAGGE
MUL_4367|M.ulcerans_Agy99 --GGVGAASLGGDGGHAGAGGAGGEGLS--GGFNTGAAGGIGGAGGAGGT
Mb3541|M.bovis_AF2122/97 TGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDPLLAAQDGGQGGTGGTGGN
MMAR_1829|M.marinum_M LAGHGGDGGAGGIGGAGGDGGSGAAGAAGDRGIIAHLDGGRGGDGGSGAD
MSMEG_0868|M.smegmatis_MC2_155 -GGHSTGTGIGGNGGIGSVYAYGNNGAVS-----GTATGGRGGDGIDGGT
TH_3810|M.thermoresistible__bu ---------------------------------------GYRTTDNNALD
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------GNAGLAGNAGL
MAV_4827|M.avium_104 -----------------------------------------IRTTGTVAL
MLBr_01556|M.leprae_Br4923 --------------------------------------LARGASLSDFAE
Mflv_5091|M.gilvum_PYR-GCK GGAGGKGGDADSMGSAGATG---GKGGNGGNGGRG-----------GLFG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDATSMGEAGATG---GKGGNGGNGGRG-----------SLFG
Rv3508|M.tuberculosis_H37Rv GGAGGNSGVGGTNGSGGAGG-AGGKGGTGGAGGSGADNPTGAGFAGGAGG
MUL_4367|M.ulcerans_Agy99 GGDSG--GVGGVNGDGGAGG-GGGRGGDGGSSTS----TSGVGGAGGAGG
Mb3541|M.bovis_AF2122/97 AGAGGTGFTQGADGNAGNGG-DGGVGGNGGNGADN-TTTAAAGTTGGAGG
MMAR_1829|M.marinum_M GGAGGSGGNGGAGGQAQAAGYADGVRGAGGSGGAG-----GAGGLAGAGG
MSMEG_0868|M.smegmatis_MC2_155 GGAGGMGEIYSG-ADGEATG--ISAGGDGGSATGA----------DSLGG
TH_3810|M.thermoresistible__bu GGHGGNGGNVGFFSLFNLGG----AGGWGGSGVDG---------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAG---NAGLAGNAGLAG---------------
MAV_4827|M.avium_104 QPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEP---------------
MLBr_01556|M.leprae_Br4923 KIDANPAALVQALFNLGEMVTATQSVGDETLELLG---------------
.
Mflv_5091|M.gilvum_PYR-GCK KGGNAGNG------------------ADGGTGGAGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 RGGNAGNG------------------GNGGTGGNGG--------------
Rv3508|M.tuberculosis_H37Rv TGGAAGAGGAGGATGTGGTGGVVGATGSAGIGGAGGRGGDGGDGASGLGL
MUL_4367|M.ulcerans_Agy99 NGGNAGFG-----VSAGGTG------GSAGDGGAGG--------------
Mb3541|M.bovis_AF2122/97 AGGAGGTGGTGG-AAGTGTGGQQGNGGNGGNGGTGGKGGTGGAGMNSLDP
MMAR_1829|M.marinum_M AGGDAYTTG----GGAGGDGGHGGDTGAGGAGGSGGVGSSTGLTGLSGHS
MSMEG_0868|M.smegmatis_MC2_155 RGGTSWVQAGYG-PTTGGKASGTAKAGHGGKASDGGKG------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------AGGTGGTGGAGGTGGTGGTGGIGG------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------NGGTGGTGGNGGTGGTGGTGGIGG------
Rv3508|M.tuberculosis_H37Rv GLSGFDGGQGGQGGAGGSAGAGGINGAGGAGGNGGDGGDGATGA------
MUL_4367|M.ulcerans_Agy99 -------------------GAGGVDGVGGASGNGGAAGAGGAGG------
Mb3541|M.bovis_AF2122/97 LLAAQDGGQGGTGGTGGNAGAGGTGFTQGADGNAGNGGDGGVGGNGGNGA
MMAR_1829|M.marinum_M PTSGGDGGDGGAGGRGAIDIAGGTGGAGGDGGTYGDGGDGGAGGDGVTGS
MSMEG_0868|M.smegmatis_MC2_155 ----------GNGGDALVMAAGATGVATGNTAIGGNGGAASANG------
TH_3810|M.thermoresistible__bu -----------------------VDVVGGNP-------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------NAGLAGNAGLAGNAGLAGNAGLAG------
MAV_4827|M.avium_104 -------------------VAAPKPLSPPVAAPLPAAPPPAAPP------
MLBr_01556|M.leprae_Br4923 -----------------SEMNYNVQVVSPEDEDRELLEPFDLTYG-----
Mflv_5091|M.gilvum_PYR-GCK -------------AGSTGGTGGTGGTGGTGGTG-----GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -------------AGSTGGTGGTGGTGGTGGTG-----GTGGTGGTGGTG
Rv3508|M.tuberculosis_H37Rv -----AGLGDNGGVGGDGGAGGAAGNGGNAGVGLTAKAGDGGAAGNGGNG
MUL_4367|M.ulcerans_Agy99 -----SGIG----AGIDGGAGGAGGTGGAAGF-----PGGGGTTGAWGTG
Mb3541|M.bovis_AF2122/97 DNTTTAAAGTTGGAGGAGGAGGTGGTGGAAGTGTGGQQGNGGNGGNGGTG
MMAR_1829|M.marinum_M QGLTATTPGGSGTNGGAGSAGGAGGSGGLGGT----LAGHGGDGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 --AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQ---GGNGGNGGNGWVQ
TH_3810|M.thermoresistible__bu ----------------DGGTPGAHGESHTPGVYT----DRQGEDGEDGTG
MAB_4284c|M.abscessus_ATCC_199 ----------------NAGLAGNAGLAGNAGLAG--NAGLAGNAGLAGNA
MAV_4827|M.avium_104 -------------LPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPV
MLBr_01556|M.leprae_Br4923 -----EDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGG
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTG-----------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTG-----------------------------------------
Rv3508|M.tuberculosis_H37Rv GAGGAGGAGDNNFNGGQGGA--GGQGGQGGLGGASTTSINANGGAGGNGG
MUL_4367|M.ulcerans_Agy99 GAGGAGGAG-----------------------------------------
Mb3541|M.bovis_AF2122/97 GKGGTGGDGALAGSSGGAGGKGGNGGDAGKAGTGSAPGTAGTGGDGGKGG
MMAR_1829|M.marinum_M GDGGFGGSGATGSSGDQGSAANPNGGRGGDGGSGADGGAGGTGGDGGAGG
MSMEG_0868|M.smegmatis_MC2_155 AYDPNGPAG-----------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAG-------------------------------------------
MAV_4827|M.avium_104 SPPQLLAPP-----------------------------------------
MLBr_01556|M.leprae_Br4923 ITQHIGAYQVG---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------GTGGAGGTGGDGGTGGTGG----------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------GTGGDGGTGGTGGTGGTGG----------------
Rv3508|M.tuberculosis_H37Rv TGGKG--GAGGAGTLGVGGSGGTGGDGGDAGSGGGGGFG--GAAGKAGGG
MUL_4367|M.ulcerans_Agy99 ---------------GAGDHGGVGVNPGDSGTAG----------------
Mb3541|M.bovis_AF2122/97 NGGIG--AAGTTGPVGTGASGGTGGSGGAGGTGGDGGAANGGTAGAGGAG
MMAR_1829|M.marinum_M QAQAAGYADGTRGAGGNGGAGGSGGLAGDGGRGGDGAVGFGGAGGDGGHG
MSMEG_0868|M.smegmatis_MC2_155 -----------TTIDKGKAAGGNGGDGGFNGTGG----------------
TH_3810|M.thermoresistible__bu --------------------TGIGGRGGNGGSSS----------------
MAB_4284c|M.abscessus_ATCC_199 -------------------LAGNAGLAGNAGLAG----------------
MAV_4827|M.avium_104 ---------------RLSVPQPVQPPVRVPQPPS----------------
MLBr_01556|M.leprae_Br4923 -----------------VDLDGSERLITFIDTPG----------------
.
Mflv_5091|M.gilvum_PYR-GCK -----------------------------TGGTGGTGGTGG------TGG
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------TGGTGGTGGTGG------TGG
Rv3508|M.tuberculosis_H37Rv GNGGRGGDGGDGASGLGL------GLSGFDGGQGGQGGAGG------SAG
MUL_4367|M.ulcerans_Agy99 ----------------------------WAGGAGGAGGAGG------SAA
Mb3541|M.bovis_AF2122/97 GNGGKGGDGGAGVTSSTA------GNSGGAGGSGGKGGDAG------AGG
MMAR_1829|M.marinum_M GNTGAGGVGGKGGVGSTTGLTGLGGHSPTNGGNGGAGGDGGKGAVDIAGG
MSMEG_0868|M.smegmatis_MC2_155 ----------------------------ATGGRGGDGAGAS----VWKAN
TH_3810|M.thermoresistible__bu -------------------------------GTHPMAEDGE--------H
MAB_4284c|M.abscessus_ATCC_199 -----------------------------NAGLAGNAAVAG---------
MAV_4827|M.avium_104 -----------------------------PPQVGGTVPQSP-------PQ
MLBr_01556|M.leprae_Br4923 -------------------------HEAFTAMRARGAKATDIAILVVAAD
Mflv_5091|M.gilvum_PYR-GCK AG--DGTGGTGGTGGTGGQGGQG-------------GQGGTGGTGG----
Mvan_1264|M.vanbaalenii_PYR-1 AG--DGLGGTGGTGGTGGFGGQG-------------GQGGTGGTGG----
Rv3508|M.tuberculosis_H37Rv AGGINGAGGAGGNGGDGGDGATGAAGLGDNGGVG--GDGGAGGAAGNGGN
MUL_4367|M.ulcerans_Agy99 FNGVNGAGGAGGNGGAGGGGGAGASGIG-AGVAG--GDGGTGGTGG----
Mb3541|M.bovis_AF2122/97 AGATPGANGIAGNGGDGGDGAAGAVGISGATGAGDGGHGGTGGAGGNGGT
MMAR_1829|M.marinum_M VGGAGGNGGAYGNGGAGGDGGDGVNGTRGLTAIAPGGSGTDGGAGSAGGA
MSMEG_0868|M.smegmatis_MC2_155 GQHSTGQTDTGGNGGRGGDGGTFVN-------AGANGNGGAGGAGG----
TH_3810|M.thermoresistible__bu VKALDGRPGLDGGNGSHG------------------GNGGHGGRGG----
MAB_4284c|M.abscessus_ATCC_199 NAAVAGNAAVAGNAAVGGVLNTGVSG----------AIGGSSHVGG----
MAV_4827|M.avium_104 HQTPPGEGTPPKPDGPGNYGGGHVPTP---------GAGGSGGSGG----
MLBr_01556|M.leprae_Br4923 DGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYG----
. .
Mflv_5091|M.gilvum_PYR-GCK -----------QGGLGGGGGTGGQGGTGGTGGQ-----------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------QGGLGGVGGTGGTGGTGGTGGQ-----------------
Rv3508|M.tuberculosis_H37Rv AGVGLT----AKAGDGGAAGNGGNGGAGGAGGAGDNNFNGGQGGAGGQGG
MUL_4367|M.ulcerans_Agy99 -----------AAGTGGAAGTGGTGGAAGAAGS-----------------
Mb3541|M.bovis_AF2122/97 GGAGGSGIDGVGGGTGGTGGNGGNGAIGGAGGDAGGSGNSGGNGGTGGKG
MMAR_1829|M.marinum_M GGYGGNG--GALAGDGGDGGDGGNGGSGGDGGSGANGGAGTNGTTTGIPD
MSMEG_0868|M.smegmatis_MC2_155 ----------VSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVG-------
TH_3810|M.thermoresistible__bu -----------FLGIGGSGGWGGHGGNGGDTDAD----------------
MAB_4284c|M.abscessus_ATCC_199 ---------AINESLGGSGSVGGSTAVGGGAHTG----------------
MAV_4827|M.avium_104 -------------GHVPTPGAGGSGGSGGGHVP-----------------
MLBr_01556|M.leprae_Br4923 ---------LVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTAD------
. . . *
Mflv_5091|M.gilvum_PYR-GCK ------------------GGTGGTGGTGGTGG------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------GGTGGTGGTGGTGG------------------
Rv3508|M.tuberculosis_H37Rv QGGLGGASTTSINANGGAGGNGGTGGKGGAGG--AGTLGVGGSGGTGGDG
MUL_4367|M.ulcerans_Agy99 ------------------AGDGGAGGAGGAGD--DGSAGVVS--------
Mb3541|M.bovis_AF2122/97 GNAGAGGAAGSNGGTVGANGTGGDGGNGGAAG--AATAGSNGGAGTGSAG
MMAR_1829|M.marinum_M GGRGGDGGHGGHGGDGGAGGHGGVAGKAQAAGYTDGTHGAGGVGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 ---------------LGNGGKGGNGGNGGNGG------------------
TH_3810|M.thermoresistible__bu ------------------GGNGGDGG------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------VGGGVSTGVG----------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ----------------AALDLRANSGMEAQG-------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
Rv3508|M.tuberculosis_H37Rv GDAGSGGGGG-----FGGAAGKAGGGGNGGVGGDGGEGASG--LGL-GLS
MUL_4367|M.ulcerans_Agy99 GDPG--------------TAGKAGGAG-----------------------
Mb3541|M.bovis_AF2122/97 GNGGTGGRGG-----SGGAGGDGIGGVGGGKGGNGADGEVGGAGGA-GGS
MMAR_1829|M.marinum_M GLAGDGGRGGNGAATASGNGGDGGNGGDPGVGGAGGKGGIGETIGLSGLG
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------TGGAGGDGGLGGLGGFGGSGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGAGGDGGLGGLGGFGGVGGTG-------------------
Rv3508|M.tuberculosis_H37Rv GFDGGQGGQGGAGGSAGAGGINGAGGAGGTGGAGGDGAPATLIGGPDGGD
MUL_4367|M.ulcerans_Agy99 -------GAGGVGGNGVAGGVNGSGGAGGAG-------------------
Mb3541|M.bovis_AF2122/97 GPNTSPGGNGGQGGQGGSGGAGGAAGAGGAGG------------------
MMAR_1829|M.marinum_M GYNPTSGGNGGDGGDGGSGSDGDFNHLAGSDGGN----------------
MSMEG_0868|M.smegmatis_MC2_155 --TYVDPSHTGAGGNGGNGGAGRIRVNNGTATG-----------------
TH_3810|M.thermoresistible__bu --------NGGSAGRGGTGGLRGVFGINGGN-------------------
MAB_4284c|M.abscessus_ATCC_199 -----VGSHVGGGISESLGGSGSVGGSTAVG-------------------
MAV_4827|M.avium_104 --------TPGTGGPGGTGGSGG---------------------------
MLBr_01556|M.leprae_Br4923 -------VAIEAHLDRGRGPVATVLVQRGTLR------------------
*
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------------GQGGL
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------------------------------GQGGQ
Rv3508|M.tuberculosis_H37Rv GGQGGIGGDGGNAGFGAGVPGDGGDGGNAGFGAGVPGDGGIGGTGGAGGA
MUL_4367|M.ulcerans_Agy99 ---------------------------------------------GAGGT
Mb3541|M.bovis_AF2122/97 -------GANGTAGNGGQGGAGGTGGAGAASSATNGGSGGAGGTGGAGGT
MMAR_1829|M.marinum_M -------GGHGGSGGAFGNGGNGGDGGTGGDGSRAFQPEIAGGAAGHGGA
MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------------TATGGN
TH_3810|M.thermoresistible__bu ---------------------------------------------GRAGL
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------------GGAH
MAV_4827|M.avium_104 ---------------------------------------------GHVPT
MLBr_01556|M.leprae_Br4923 --------------------------------------------IGDSVV
Mflv_5091|M.gilvum_PYR-GCK GGPGGS--------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GGPGGS--------------------------------------------
Rv3508|M.tuberculosis_H37Rv GGAGAD-GDPSIDGGQGGAGGHGGQGGKGG---------LNSTGLASAAS
MUL_4367|M.ulcerans_Agy99 GGAGAS-GVP--------------------------------------AS
Mb3541|M.bovis_AF2122/97 GGAGGD-GVGGAGGGNGGHGGDAGDGGNGANGNNRSSGSFLAAGGTGGAA
MMAR_1829|M.marinum_M GGAGGDGGYLAGNGGTGGTGGAGGAGGTGAAGE-----PQFENGQNGGAG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGN------------------------------------------GD
TH_3810|M.thermoresistible__bu GGRGXX--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TGVGGG--------------------------------------------
MAV_4827|M.avium_104 PGAGTP--------------------------------------------
MLBr_01556|M.leprae_Br4923 AGDAYG--------------------------------------------
* .
Mflv_5091|M.gilvum_PYR-GCK ----TGGAGGAGG-----------------------------------QA
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGAGGAGG-----------------------------------QA
Rv3508|M.tuberculosis_H37Rv GDGGNGGAGGAGGNGGDGDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNA
MUL_4367|M.ulcerans_Agy99 VDGGDGGAGGAGG-----------AAGTGGSG------------GSAGNT
Mb3541|M.bovis_AF2122/97 GDGGQGGQGGAGG-GAGGQGGAGGAGGTGGNGGN-ITGGTAGTAGAAGNG
MMAR_1829|M.marinum_M GIGRAGGAGGDGG-NGGHAHAAGFQNGAGGAGGDGGQGGTGGGGGFGGDG
MSMEG_0868|M.smegmatis_MC2_155 ADGHRGGKGGDGG------------------------EALIRATVIGSNA
TH_3810|M.thermoresistible__bu -----XXGGGVG------------------------------------AA
MAB_4284c|M.abscessus_ATCC_199 ----VSTGVGVGS-----------------------------------HV
MAV_4827|M.avium_104 -----GGSGG-------------------------------------GHL
MLBr_01556|M.leprae_Br4923 ---RVRRMVDEHG----------------------------------VDI
.
Mflv_5091|M.gilvum_PYR-GCK GTAGKGGLFGGSGSAGKAGAT-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GVAGKGGLFGGSGSAGTAGVT-----------------------------
Rv3508|M.tuberculosis_H37Rv GIGGAGGRGGDGGAGDSGALS--QDGNGFAGGQGGQGGVGGNAGAGGING
MUL_4367|M.ulcerans_Agy99 GAGGAGGAGGAGGSAASTGVN--GDG-----------------------G
Mb3541|M.bovis_AF2122/97 GAAGKGGAGGQGGTGGGTGGQGGAGGDGGAGGTGGDRTVGGGTVPAGSGG
MMAR_1829|M.marinum_M KAGYNQRAGGDGGAGGDGGFG----GTGGTGGLNGDGTTRATSGANGIRG
MSMEG_0868|M.smegmatis_MC2_155 SGTATGGDGGNGGTLGATNGTG-GAATIVAYNVVQANPQASGTATDGHGG
TH_3810|M.thermoresistible__bu VRSGNGVFSGGGGTP-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVG-----------------------------
MAV_4827|M.avium_104 PFPGAGSTPGGSGGGHLPTPG-----------------------------
MLBr_01556|M.leprae_Br4923 EAALPSSPVQVIGFTSVPGAG-----------------------------
.
Mflv_5091|M.gilvum_PYR-GCK -GAAGASGGKGAQG--------ATGAQGATGAQGATGATGAAGKAG----
Mvan_1264|M.vanbaalenii_PYR-1 -GASGASGGKGAQG--------ATGAQGATGAQGATGATGASGAQG----
Rv3508|M.tuberculosis_H37Rv AGGTGGTGGAGGDGQNGTTGVASEGGAGGQGGDGGQGGIGGAGGNAGFGA
MUL_4367|M.ulcerans_Agy99 AGGAGGVGGLGGDS-------AATAGGGGAGGDGGKGGAGGAGVNG-VGG
Mb3541|M.bovis_AF2122/97 QGGNAGGGGAGGQG-------GADGGSGGDGGDAGTGGNGGNGGNRNSGN
MMAR_1829|M.marinum_M DGGSGGTGGNGLGG----RTENGDGGHGGKGGVGGYGSVGGVGGSGGHGG
MSMEG_0868|M.smegmatis_MC2_155 SGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGV
TH_3810|M.thermoresistible__bu ------SAGFGVPT--------TIQFPAGSCTSRAVSREGIMPSSR----
MAB_4284c|M.abscessus_ATCC_199 -----GGAHTGVGG--------GVNTGVGVGSHVGGGISESLGGSG----
MAV_4827|M.avium_104 ----AGTPGGGLGG---------FGGGHAPAPGGGLGGGGGHAPAP----
MLBr_01556|M.leprae_Br4923 -DNFLVVDEDRIAR--------QIADRRSARKRNALAARSRKRISLEDLD
. . .
Mflv_5091|M.gilvum_PYR-GCK -----------ATGAAGAAGAAG-SAGTTGAQGSAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------SAGSAGSAGVAG-SAGTTGAQGSAG--------------
Rv3508|M.tuberculosis_H37Rv GVPGDGGI--GGTGGAGGAGGAG-ADGDPSIDGGQG--------------
MUL_4367|M.ulcerans_Agy99 ---GDGGK--GGTGGAGGAGGAG-SDGIIPSNGGLG--------------
Mb3541|M.bovis_AF2122/97 GTGGAGGN--GGGGANGGAGGAGGSGGGTGGNGGAGGDAGDAGNGGNGNG
MMAR_1829|M.marinum_M NGGQSGTPRFGGHGGDGGAGGAGVVTGGTGGTGGAGG------NGLDGTA
MSMEG_0868|M.smegmatis_MC2_155 VNTTANAAN-PGSATGTATGGDGGKATGTASQGGNGG-------------
TH_3810|M.thermoresistible__bu ----------AASARAGAACASSTSRSRRSFCCSRA--------------
MAB_4284c|M.abscessus_ATCC_199 -----------SVGGSTAVGGGAHTSAINDALGGSGS-------------
MAV_4827|M.avium_104 ------------GGGLGGFGGGHSGGGLGGLGGGHK--------------
MLBr_01556|M.leprae_Br4923 SALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALR----------
. .
Mflv_5091|M.gilvum_PYR-GCK -TNGANGANGSQ--------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -TNGANGANGSQ--------------------------------------
Rv3508|M.tuberculosis_H37Rv -GAGGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNG--------GD
MUL_4367|M.ulcerans_Agy99 -GNGGNGGNGGQ-----------AFGDG----------------------
Mb3541|M.bovis_AF2122/97 TGNGGNGGNGGIAGMGGNGGAGTGSGNGGNGGSGGNGGNAGMGGNSGTGS
MMAR_1829|M.marinum_M KAAGGNGGNGGVGGAGG-----VAGGAGGAGGAGGAGGNG-------PGG
MSMEG_0868|M.smegmatis_MC2_155 -PSWVQSGYGSTLG---------GNATG----------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----GAAGKAGATGTTGATG-----------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----GAAGKAGATGTTGATG-----------------------------
Rv3508|M.tuberculosis_H37Rv GDGFIGGSGGTGGTGGDAGVGGLANTGGTAGNAGIGGAGGRGGDGGAGDS
MUL_4367|M.ulcerans_Agy99 ----VGGAGGIGGKGGNAAIGTIVING-----------------------
Mb3541|M.bovis_AF2122/97 GDGGAGGNGGAAGTGGTGGDGGLTGTGGTGGSGGTGGDGGNGGNGGNGAD
MMAR_1829|M.marinum_M LFGPDGGSGGSGGNGGAGGSGGTTGTGGAGGGGGNGGNGGTGFSTNNVAS
MSMEG_0868|M.smegmatis_MC2_155 --TATAGKGGEASNGGVAGNGGNALVMAAG--------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----VGGSTAVGGGAHTSAIN-----------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --VIDRGVGGITETNVNLASAS----------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------AAGED--GDAGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------AAGDA--GDPGSEAVD
Rv3508|M.tuberculosis_H37Rv GAL----SQDGNGFAGGQGGQGGVGGNAGAGGINGAGGT-GGTGGAGGDG
MUL_4367|M.ulcerans_Agy99 -------------------------------GVGGAGGS-GGLGGATEDG
Mb3541|M.bovis_AF2122/97 NTANMTAQAGGDGGNGGDGGFGGGAGAGGGGLTAGANGT-GGQGGAGGDG
MMAR_1829|M.marinum_M GGMG---GGGGKGGGGGDGLIGGAGGGGGDGGNGAAGLTSGGNGGAGGAG
MSMEG_0868|M.smegmatis_MC2_155 -------------------TTGVATGNTATGGDGGAATTAGATGGAGGFS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------ESMNSSINASHSSSMNE
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------------------------DAIIIGFNVRAEGKATELA
Mflv_5091|M.gilvum_PYR-GCK IN------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 IN------------------------------------------------
Rv3508|M.tuberculosis_H37Rv QNGTTG--------------------VASEGGAGGQGGDGGQGG------
MUL_4367|M.ulcerans_Agy99 --------------------------------------------------
Mb3541|M.bovis_AF2122/97 GNGAIGGHGPLTDDPGGNGGTGGNGGTGGTGGAGIGSLGGGTGG------
MMAR_1829|M.marinum_M GAGGAG------------------RTTSGDGGSGGNGGTGGEGGGDILVA
MSMEG_0868|M.smegmatis_MC2_155 NIAAIHG-------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S-------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SR------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------GGAGGAGGAG------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------GGAGGAGGAG------------------
Rv3508|M.tuberculosis_H37Rv --IGGAGGNAGFGAGVPGDGGIGGTGGAGGAGGAGADGDPS-IDGGQGGA
MUL_4367|M.ulcerans_Agy99 ---------------------VGGVGCAGGAG------------------
Mb3541|M.bovis_AF2122/97 --DGGNGGTGGNGGTGGEGGEVGGAGGTGGAAGNGGDGGTGGTGGGDGGA
MMAR_1829|M.marinum_M PVVAGTGGAGGEGGAGGYSNTVGGVAGNGGAGGSGGTGGTLAAHKVVYTS
MSMEG_0868|M.smegmatis_MC2_155 ------AITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----GEGGEGGDGGK------------GGAGAEGGAGGGGGAG-------
Mvan_1264|M.vanbaalenii_PYR-1 ----GEGGEGGAGGA------------GGDGSEGGAGGSGGAG-------
Rv3508|M.tuberculosis_H37Rv GGHGGQGGKGGLNSTGLASAASGDGGNGGAGGAGGNGGAGGLG------G
MUL_4367|M.ulcerans_Agy99 ----GNGGRGDMLFT-----------VGGSGGTGGDGGGGGSA------S
Mb3541|M.bovis_AF2122/97 GGTGGTGGTGGLGDPRVGGSG-GDGGTGGSGGAAGNGGNGGNAGA----G
MMAR_1829|M.marinum_M SGRGGVGGTGGVGGS-------STYGTGGVGGTGGTGGMGGAADLNNYAA
MSMEG_0868|M.smegmatis_MC2_155 SAVAGNGGDGGVNGTG-----------GASGGDGGNGGNTSVWK------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------FGSSMGSHGAAGTGFEAQG-----
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -----EGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFR
Mflv_5091|M.gilvum_PYR-GCK GSGAGGAGGAGGSGGSGGSGGSG---------------------------
Mvan_1264|M.vanbaalenii_PYR-1 GSGTGGAGGAGGSGGSGGSGGAG---------------------------
Rv3508|M.tuberculosis_H37Rv GGGTGGTNGNGGLGGGGGNGGAGGAGGTPTGSGTEGTGGDGGDAGAGGNG
MUL_4367|M.ulcerans_Agy99 GSGTGGSGGTGGVGGIGGDGKLG---------------------------
Mb3541|M.bovis_AF2122/97 GNGNGGTGGAGGIGGTGGNGGDAEPGVPPGAGGAGGAGTTGGKGGTGGNG
MMAR_1829|M.marinum_M ASGAGGTGGIGGAGVTGGDGGRGGTGGRSAYIGIPGTGGIGGIGGLGTAG
MSMEG_0868|M.smegmatis_MC2_155 -SGGQTADGEHNTGGNGGNGGDG---------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -HAQGHASETAHTTLPGAEHH-----------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SSKVGIIAGCIISSGVVRRNAKVR--------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------GSGGAAGDSDD------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------GSGGAAGDSD-------------------------------
Rv3508|M.tuberculosis_H37Rv GSATGVGNGGNGGDGGNGG--DGGNGAPGGFG-----GGAGAGGLGGSGA
MUL_4367|M.ulcerans_Agy99 ---------GFGGDGGDGG--DGGFGVIGGQG-----GGGGFGGLGGTGA
Mb3541|M.bovis_AF2122/97 SGTGSGGTGGDGGTGGGGG--NGGTGWNGGKGDTGSGGGAGDGGKAPAGG
MMAR_1829|M.marinum_M LG----GYGGDGGTGGSGHGVAGGYGGAGGRGGTSTVDGQRIPGVNGDSG
MSMEG_0868|M.smegmatis_MC2_155 ---------SEPGPGGNGAGGAGGNGGTGGTT----AGGSGNGGNGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------LLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIK
Mflv_5091|M.gilvum_PYR-GCK -----------------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------------------
Rv3508|M.tuberculosis_H37Rv GGGTDGDDGNGGSPGTDGS----
MUL_4367|M.ulcerans_Agy99 GG-APSDKGINGEPGNPG-----
Mb3541|M.bovis_AF2122/97 TGGAGGDGGAGGKGGSGGV----
MMAR_1829|M.marinum_M QPPPPGYTGPPGAGGSGGAPGGL
MSMEG_0868|M.smegmatis_MC2_155 NGGADGTPGTAGTTGANNP----
TH_3810|M.thermoresistible__bu -----------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------
MAV_4827|M.avium_104 -----------------------
MLBr_01556|M.leprae_Br4923 EGDVIESYELVEKQRA-------