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SFVLLPPEINSARMHLGAGPGPMLAAATAWDGLAAELFAAASAFGAVTSGLAGGSWQGPASTAMASAAQP YLVWLTTASVQAEQAASQVRAALASFEAALVATVSPPAIDANRTVLTALVNANVLGLAAPAIAAVEAQYE QMWAQDVAAMLGYHAGASAAASALTPFAVSGLVRQLGNAAAASLASAAPASAAVAAAAEAAVADPVSALG LPSLGLAAATPLNLGAANVGTSNLGFGNIGSGNIGNGNNGDGNLGGGNLGSYNLGWGNLGGANQGFGNAG SNNQGFANTGSNNQGFANTGSFNVGFGNTGSNNIGIGLSGDGKIGFGSLNSGSGNIGLFNSGTNNIGFFN SGTGNFGVLNSGSYNTGFGNSGEASTGVFNPGNANTGWANTGNHNTGSFNAGNTNTGGFNPGNLNTGWAN TGDVDTGAFISGSYSNGLFWQDDYRLLGIDLKINFGGTSGDYAVSIPLDNTFSATVPTITTPGTTIPKQT FLNGGYIGPITIPSITIVGPPINATVGPATLDLSLSYDVSPIQLQLLYIPPTTGLGNTSSSPSSGFFNQG DGGSSGLFNTTSGPFGVSGLLNYGDLESGALNFGNTISGIHNTSGLELAPLEPARISGVGNIGSDLAGVF RDGPDATTFNVGVGNDGGLNFGSANIGDYNFGNANIGNLNLGSANIGFGNIGGGNVGDYNLGSGNLGSAN IGFGNAGPGLTAAFNNIGFGNTGDNNIGFGNTGNGNIGFGNTGNGNIGIGLNGDGLQGFGGWNSGSGNIG LFNSGTDNVGIGNSGTGNSGIGNTGSYNTGIGNVGVANTGLFNIGNLNTGIGNPGNYNSGAHNVGSTNTG GANQGDYNTGWLNLGDYNTGLANVGNVNTGALISGNYDNGILWRSDYRAQGGFSYAIGLVPITTSLNLSV PIDIPISATVGNTVIEGFTIPEIPIGAYGVVSGNIGPETFPTITIVGPTIDIGVGGTQSVFTPSFVVDTG LVQAIVLDLPSGPGVGNSTSVESSGFFNSGDGSASGFGNGGGSNSGFLNFATDSLGNSGFKNYGTLESGI ANLGNSVSGVFNTSALDLLTAANVSGVSNFGSNLSGFFLAGDSADRIFNVGVANDGSFNIGSANLGDYNF GLGNVGNTNFGPGNLGSTNIGGANIGDTNFGFGNIGANNFGFGNSGASLTDGNHNIGFGNTGSNNIGIGN TGDGNIGFGNTGNDNTGIGLNGDGLQGFGGWNSGSGNIGVFNSGTDNVGIGNSGTGNSGIGNSGSYNTGI GNSGLANTGLFNSGSFNTGIGNVGSYNTGTFNVGDHNTGNFNTGQSNTGSLNVGDLNTGWANTGNVNTGA LISGDYNNGLLWRGDYQGNLGAFNYTVTVPTTTADLNLSFPISLPISIDIGKIVIESFTLPKITANLDGK IKYKIPGVGKVNVKLYWDLKISPITFSDITISGPTLTSTIGNTDGSTVLGVDTDGTIGPLTIPLIDIPAG PGFGNSSTSPSSGFFNSGDGSSSGFGNVGINNSGFFNVSFIDGNSGLRNYGNLESGLGNLGNSISGLLNT STLDIDTPAVVSGIGNIGTNLSGFYNDASGNAPDSTFNLGFADIGIFNAGAANTGNYNLGFGNIGDGNVG AANVGNFNFGGANIGDTNFGFGNIGNNNFGFGNSGASLTNGNHNIGFGNTGSNNFGFGNTGDGNIGFGNT GDGNIGIGLSGDGLRGFGALNTGSGNVGLFNSGTNNIGLFNSGSDNIGIGNSGIGNAGLFNSGNYDTGMF NAGIVNTGIGNAGDFNTGTFNAGDANTGNANSGSYNTGGFNSGNYDTGWANTGDVDTGIFISGNYSNGIL ARGDYQGLVGVPLFDIAAAPGFGNTTTSYSSGFFNNGAGSGSGFFNSGTDVSGYGNLGAVQSGLANYGNS VSGLFNTSSLDTATAAYVSGVGNAGANLAGLFRDSAGGTTLNVGFANLGVLNLGAANVGDYNVGTANVGG INFGGANIGDLNFGAGNLGSTNFGFGNLGSNNFGFGNSGVSLANGNHNFGFGNTGSNNFGFGNTGDGNIG FGNTGDGNIGIGLNGDGLRGFEALNSGTDNVGLFNSGTGNVGIGNSGTGNWGIGNSGNYNTGVGNTGAAN TGMFNSGIANTGVANAGSYNTGNLNAGDINTGSFNTGVSNTGYFNVGDTNTGIANLGDINTGGFNSGSMN NGFLLRGDELGQLGFNYTLNIPTLPVDLDIYANFQTPISLDVGGTTIHSFDISAFTISGKYGYSYKVLGI KFNYPFKYSFDIPAITIPSIQIGGSSQNFTVGPPALNTTINFDGGPLNIAVDMDPAPGFFNFTNNDSSGF FNSGKGFTSGLGNIGGYDSGFLNGSMDPFGSGSSQTSGVYNFGELQSGLVNVGNTVSGFFNTSKVKDAAA YISGFFNTGSNLSGFFNTGTGP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0641 | - | - | 100% (2403) | PPE family protein |
M. marinum M | MMAR_1639 | - | 0.0 | 47.94% (2549) | PPE family protein |
M. marinum M | MMAR_0642 | - | 0.0 | 46.31% (2643) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0362c | PPE8 | 0.0 | 46.55% (2623) | PPE family protein |
M. gilvum PYR-GCK | Mflv_0325 | - | 1e-28 | 36.14% (202) | PPE protein |
M. tuberculosis H37Rv | Rv0355c | PPE8 | 0.0 | 46.55% (2623) | PPE family protein |
M. leprae Br4923 | MLBr_01182 | - | 2e-27 | 39.11% (179) | PPE-family protein |
M. abscessus ATCC 19977 | MAB_2254c | - | 2e-25 | 34.16% (202) | PPE family protein |
M. avium 104 | MAV_0535 | - | 4e-51 | 39.66% (353) | PPE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-38 | 26.04% (1202) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3113 | - | 2e-28 | 38.94% (208) | PUTATIVE PPE protein |
M. ulcerans Agy99 | MUL_0965 | - | 1e-178 | 44.37% (897) | PPE family protein |
M. vanbaalenii PYR-1 | Mvan_0415 | - | 1e-32 | 38.25% (217) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0641|M.marinum_M -------------MSFVLLPPEINSARMHLGAGPGP-------------M MUL_0965|M.ulcerans_Agy99 -------------MNFIMLPPEINSARIFAGAGVGP-------------T Mb0362c|M.bovis_AF2122/97 -------------MSFAVLPPEINSARLYVGAGLAP-------------M Rv0355c|M.tuberculosis_H37Rv -------------MSFAVLPPEINSARLYVGAGLAP-------------M Mflv_0325|M.gilvum_PYR-GCK MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGS-------------L Mvan_0415|M.vanbaalenii_PYR-1 ----------MSSPVWMALPPEVHSALLSSGPGPGS-------------M MAB_2254c|M.abscessus_ATCC_199 ----------MSAPIWMAFPPEVHSALLGAGPGPGP-------------L TH_3113|M.thermoresistible__bu ----------------MALPPEVHSTLLRTGPGPGA-------------L MAV_0535|M.avium_104 -------MLNFGQLDFAQLPPEINSGLMYSGPGAGP-------------L MLBr_01182|M.leprae_Br4923 ------------MFDFAALSPETNSTRMYLGPGSSP-------------I MSMEG_0868|M.smegmatis_MC2_155 ---------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPK . : *.* . MMAR_0641|M.marinum_M LAAATAWDGLAAELFAAASAFGAVTSGLAGGSWQGPASTAMASAAQPYLV MUL_0965|M.ulcerans_Agy99 LAAAAAWDALAADLASAAQSFAAITVGLVGEAWQGAAATAMAAAARPYAS Mb0362c|M.bovis_AF2122/97 LDAAAAWDGLADELGSAAASFSAVTAGLAGSSWLGAASTAMTGAAAPYLG Rv0355c|M.tuberculosis_H37Rv LDAAAAWDGLADELGSAAASFSAVTAGLAGSSWLGAASTAMTGAAAPYLG Mflv_0325|M.gilvum_PYR-GCK LAAGVAWQSLSAEYASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLA Mvan_0415|M.vanbaalenii_PYR-1 LAAAATWQSLSAEYAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLA MAB_2254c|M.abscessus_ATCC_199 LAAAAQWHALSYEYSMAATELTQLLGVTAAGVWQGSSATQYVASHTPYLA TH_3113|M.thermoresistible__bu SAAADAWRMLSDEYRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLF MAV_0535|M.avium_104 LAAAAAWNGLAAELRSAAASFGSVITGVGDAGWQGPAASSMMAAAAPQLA MLBr_01182|M.leprae_Br4923 LTAAAAWVVLAKELTAAAQGLQSAVEALLT-TFEGESAAALAERVTPYEK MSMEG_0868|M.smegmatis_MC2_155 FPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQAT *. : . MMAR_0641|M.marinum_M WLTTASVQAEQAASQVRAALASFEAALVATVSPPAIDANRTVLTALVNAN MUL_0965|M.ulcerans_Agy99 WLGTAAARAAVTAAQANAAAAVFEAAQAATAHPELVAANRNQLVSLVVSN Mb0362c|M.bovis_AF2122/97 WLSAAAAQAQQAATQTRLAAAAFEAALAATVHPAIISANRALFVSLVVSN Rv0355c|M.tuberculosis_H37Rv WLSAAAAQAQQAATQTRLAAAAFEAALAATVHPAIISANRALFVSLVVSN Mflv_0325|M.gilvum_PYR-GCK WLAQQSAVSAATAVQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTN Mvan_0415|M.vanbaalenii_PYR-1 WLAQQSAAGAAAAAQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATN MAB_2254c|M.abscessus_ATCC_199 WLTQQSATSAANAALHETSAAAYTTALAAMPTLPELATNHTVHGILVGTN TH_3113|M.thermoresistible__bu WLTDTAAAAAAAGAQLEAAAAAHASALAAMPTMAELTANRTTHAALVATN MAV_0535|M.avium_104 WLSGTAGRAELAAGQALAAVSAYETAFAETVPPPVIAANRALLLQLLATN MLBr_01182|M.leprae_Br4923 WLTQNAASAELTATQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSN MSMEG_0868|M.smegmatis_MC2_155 STNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVT : : * . MMAR_0641|M.marinum_M VLGLAAPAIAAVEAQYEQMWAQDVAAMLGYHAGASAAASALTPFAVSGLV MUL_0965|M.ulcerans_Agy99 LFGQNAPAIASTEAAYDQLWAQDVAAMAGYHSGASAVAAQLAPWQQA--L Mb0362c|M.bovis_AF2122/97 LLGQNAPAIAATEAAYEQMWAQDVAAMFGYHAGASAAVSALTPFGQALPT Rv0355c|M.tuberculosis_H37Rv LLGQNAPAIAATEAAYEQMWAQDVAAMFGYHAGASAAVSALTPFGQALPT Mflv_0325|M.gilvum_PYR-GCK FLGINTIPIALNEADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSV Mvan_0415|M.vanbaalenii_PYR-1 FLGINTIPIAMTEADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFV MAB_2254c|M.abscessus_ATCC_199 FFGINTIPIALNEADYVRMWVQAATTMGVYQGVSSTAVAAAAPTTTSPLI TH_3113|M.thermoresistible__bu FFGVNTIPIAVNEADYARMWIQAATTMATYEAVASAAVSATPRTVAPPPI MAV_0535|M.avium_104 FLGQNTPAIADVEAQYGEMWAQDAAAMYGYALASAAASTLPPFEPAKPAT MLBr_01182|M.leprae_Br4923 IFGQNSTAIAEKEAEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLG MSMEG_0868|M.smegmatis_MC2_155 LGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVP . . * :* . : MMAR_0641|M.marinum_M RQLGNAAAASLASAAPA--------------------------------- MUL_0965|M.ulcerans_Agy99 RTLQNRVAGATTALPPP--------------------------------- Mb0362c|M.bovis_AF2122/97 VAGGGALVSAAAAQVTTRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGN Rv0355c|M.tuberculosis_H37Rv VAGGGALVSAAAAQVTTRVFRNLGLANVGEGNVGNGNVGNFNLGSANIGN Mflv_0325|M.gilvum_PYR-GCK LLPGVGEAGRAAADMSA--------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 LAPGVGEAGRAAADVTA--------------------------------- MAB_2254c|M.abscessus_ATCC_199 MPPGS-ELSRMAADMSG--------------------------------- TH_3113|M.thermoresistible__bu LGAGTGESATAAITGAH--------------------------------- MAV_0535|M.avium_104 DPAGLARQAAATAQAAG--------------------------------- MLBr_01182|M.leprae_Br4923 VNEVGLAQEVVEEVVEE--------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TVASAVLDPTQIVNWLIYQP------------------------------ MMAR_0641|M.marinum_M ------------------SAAVAAAAEAA--------------------- MUL_0965|M.ulcerans_Agy99 ------------------GPAAAAALP----------------------- Mb0362c|M.bovis_AF2122/97 GNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIG Rv0355c|M.tuberculosis_H37Rv GNIGSGNIGSSNIGFGNVGPGLTAALNNIGFGNTGSNNIGFGNTGSNNIG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M ---VADPVSALGLPSLGLAAATPLNLGAANVGTS---------------- MUL_0965|M.ulcerans_Agy99 --------------------------GAAAVGFP---------------- Mb0362c|M.bovis_AF2122/97 FGNTGDGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGN Rv0355c|M.tuberculosis_H37Rv FGNTGDGNRGIGLTGSGLLGFGGLNSGTGNIGLFNSGTGNVGIGNSGTGN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 WGIGNSGNSYNTGFGNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNS Rv0355c|M.tuberculosis_H37Rv WGIGNSGNSYNTGFGNSGDANTGFFNSGIANTGVGNAGNYNTGSYNPGNS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 NTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNFNNGFLWRGDH Rv0355c|M.tuberculosis_H37Rv NTGGFNMGQYNTGYLNSGNYNTGLANSGNVNTGAFITGNFNNGFLWRGDH Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 QGLIFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAI Rv0355c|M.tuberculosis_H37Rv QGLIFGSPGFFNSTSAPSSGFFNSGAGSASGFLNSGANNSGFFNSSSGAI Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GNSGLANAGVLVSGVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMS Rv0355c|M.tuberculosis_H37Rv GNSGLANAGVLVSGVINSGNTVSGLFNMSLVAITTPALISGFFNTGSNMS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GFFGGPPVFNLGLANRGVVNILGNANIGNYNILGSGNVGDFNILGSGNLG Rv0355c|M.tuberculosis_H37Rv GFFGGPPVFNLGLANRGVVNILGNANIGNYNILGSGNVGDFNILGSGNLG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M ---NLGFGNIGSGNIGNGNNGDGNLGGGNLGSYNLGWGNLGGANQGFGNA MUL_0965|M.ulcerans_Agy99 ---VLHIGNIGFANLSVGNIGDYNLGSGNTGSFNLGSGNIGDASLGSGNA Mb0362c|M.bovis_AF2122/97 SQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNV Rv0355c|M.tuberculosis_H37Rv SQNILGSGNVGSFNIGSGNIGVFNVGSGSLGNYNIGSGNLGIYNIGFGNV Mflv_0325|M.gilvum_PYR-GCK --FAAQPMAAQAGAAFDVSNIIADIIRLYGEVLRFLFEPIFNFLRD-PIG Mvan_0415|M.vanbaalenii_PYR-1 --FAAQAQAAEAGSALDLSNIIADLIRAYGELLRFLFEPIFDFLRD-PLG MAB_2254c|M.abscessus_ATCC_199 --FAAQAQATESGSALDSSNSVIDQL--------------LNFFRD-PLG TH_3113|M.thermoresistible__bu --VTAELRAAESRTLLDEINELIDRLFAP-----LFPPGFADALPDGLLG MAV_0535|M.avium_104 --TGAGDSAQG-------------------------------------LG MLBr_01182|M.leprae_Br4923 ------------------------------------------------VV MSMEG_0868|M.smegmatis_MC2_155 -LHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTADNPNGGTGGL MMAR_0641|M.marinum_M GSNNQGFANTGSNNQGFANTGSFNVGFGNTGSNNIGIGLSGDGKIGFGSL MUL_0965|M.ulcerans_Agy99 GDSNVGFGNFGSNN----------VGIGNNGNNNIGIGLNGDDLIGIGAL Mb0362c|M.bovis_AF2122/97 GDYNVGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIA Rv0355c|M.tuberculosis_H37Rv GDYNVGFGNAGDFNQGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNIA Mflv_0325|M.gilvum_PYR-GCK NTFALITDFLTNPVQALITWGPFLLAVVYQAVSWVGASILYPSLFLLPLL Mvan_0415|M.vanbaalenii_PYR-1 NTIKLITDFLTNPAQALITWGPFLAAVAYQAVSWVGASILYPSLLLLPLV MAB_2254c|M.abscessus_ATCC_199 TLRQIIEDFIRNPGAALATWLPFLLVLASMTYVLF-AQVFW--LFWAALL TH_3113|M.thermoresistible__bu TLLAPLLPGATGDGPPMATIMSFLLMGLSNPAYLFPVLVYL---LFTGVV MAV_0535|M.avium_104 AAPQSMSTLAAGTNNPPAANPGFSLGGIS-----------------LNPE MLBr_01182|M.leprae_Br4923 EEVVEAEQAISQAALDQAVNEGMEATVVPQVDQQVNVDVATPQTAVPDSS MSMEG_0868|M.smegmatis_MC2_155 LFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGLDGGNGGSGGL MMAR_0641|M.marinum_M N---SGSGNIGLFNSGTNNIGFFNSGTGNFGVLNSGSYNTGFGN------ MUL_0965|M.ulcerans_Agy99 N---SGAGNLGFGNSGTNNIGFFNSGDNNIGFFNSGSGNFGFEN------ Mb0362c|M.bovis_AF2122/97 SGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTGNWGIGNPGTDNT Rv0355c|M.tuberculosis_H37Rv SGWNSGTGNSGLFNSGTNNVGIFNAGTGNVGIANSGTGNWGIGNPGTDNT Mflv_0325|M.gilvum_PYR-GCK ATTLAIVAGVGQHLLSLLNTPPAEEAAEEPAPAQSAPSRPDQQS------ Mvan_0415|M.vanbaalenii_PYR-1 ATTLAIVLGVGAYLLENLPAPAEDAPAEEPAASSPAPTRADQPS------ MAB_2254c|M.abscessus_ATCC_199 SAPLWLPLLILAAWQYLQPPAVDAAPADEIRPELGSTVNGQREH------ TH_3113|M.thermoresistible__bu HTTVAVSG-MLAQLVPLMPALLPVAVAALGGLAGVWAGLSGLAG------ MAV_0535|M.avium_104 GDGLVIGGPLGDLLEGLTGSQTLDASTPFDAFIRLIS--PTRLF------ MLBr_01182|M.leprae_Br4923 SAAAPQLWGGFAQHLSPINDTLSMINNHAGMANAGLSLVNGMGS------ MSMEG_0868|M.smegmatis_MC2_155 LMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTGGIGG------ MMAR_0641|M.marinum_M ----SGEASTGVFNPGNANTGWANTGNHNTGSFNAGNTNTGGFNPGNLNT MUL_0965|M.ulcerans_Agy99 ----AGDINTGFWNGRDTNTGFGNSG------------------------ Mb0362c|M.bovis_AF2122/97 GILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFNVGDTNT Rv0355c|M.tuberculosis_H37Rv GILNAGSYNTGILNAGDFNTGFYNTGSYNTGGFNVGNTNTGNFNVGDTNT Mflv_0325|M.gilvum_PYR-GCK ----FPATMSAPPPPSGAPIAANTVSA----------------------- Mvan_0415|M.vanbaalenii_PYR-1 ----PAIAVSAPPPPSSAAATVGTVAT----------------------- MAB_2254c|M.abscessus_ATCC_199 ----IEPLPAIALAPTATPVPTASASA----------------------- TH_3113|M.thermoresistible__bu ----LAGLTAVPAADGGASAAPVPAGG----------------------- MAV_0535|M.avium_104 ----TTSFKDIQGIAQGMMPAAKSAGE----------------------- MLBr_01182|M.leprae_Br4923 -----AMKSLAPTTTKAAESAFKAMGS----------------------- MSMEG_0868|M.smegmatis_MC2_155 ----TGGGLFGLLGHSGSTGAAGAAGN----------------------- . MMAR_0641|M.marinum_M GWANTGDVDTGAFISGSYSNGLFWQDDYR-------------LLGIDLKI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAIDLSVTT Rv0355c|M.tuberculosis_H37Rv GSYNPGDTNTGFFNPGNVNTGAFDTGDFNNGFLVAGDNQGQIAIDLSVTT Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M NFGGTSGDYAVSIPLDNTFSATVPTITTPGTTIPKQTFLNGGYIG---PI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 PFIPINEQMVIDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFFFGPVNL Rv0355c|M.tuberculosis_H37Rv PFIPINEQMVIDVHNVMTFGGNMITVTEASTVFPQTFYLSGLFFFGPVNL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M TIPSITIVGPPINATVGPATLDLSLSYDVSPIQLQLLYIPPTTGLGNTSS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 SASTLTVPTITLTIGGPTVTVPISIVGALESRTITFLKIDPAPGIGNSTT Rv0355c|M.tuberculosis_H37Rv SASTLTVPTITLTIGGPTVTVPISIVGALESRTITFLKIDPAPGIGNSTT Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M SPSSGFFNQGDGGSSGLFNTTSGPFGVS-----------GLLNYGDLESG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 NPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNLGSLQSG Rv0355c|M.tuberculosis_H37Rv NPSSGFFNSGTGGTSGFQNVGGGSSGVWNSGLSSAIGNSGFQNLGSLQSG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M ALNFGNTISGIHNTSGLELAPLEPARISGVGNIGSDLAGVFRDGPDATTF MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 WANLGNSVSGFFNTSTVNLS--TPANVSGLNNIGTNLSGVFR-GPTGTIF Rv0355c|M.tuberculosis_H37Rv WANLGNSVSGFFNTSTVNLS--TPANVSGLNNIGTNLSGVFR-GPTGTIF Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M NVGVGNDGGLNFGSANIGDYNFGNANIGNLNLGSANIGFGNIGGGNVGDY MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 NAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNIGPANLGNY Rv0355c|M.tuberculosis_H37Rv NAGLANLGQLNIGSANLGDFNLGSGNVGSFNVFSGNQGSYNIGPANLGNY Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M NLGSGNLGSANIGFGNAGPGLTAAFNNIGFGNTGDNNIGFGNTGNGNIGF MUL_0965|M.ulcerans_Agy99 ------------------------LSNFGFGNSGVNNVGAGNGGSSNVGL Mb0362c|M.bovis_AF2122/97 NIGFANLGNYNIGFGNAG------DFNQGFANTGNNNIGFANTGNNNIGI Rv0355c|M.tuberculosis_H37Rv NIGFANLGNYNIGFGNAG------DFNQGFANTGNNNIGFANTGNNNIGI Mflv_0325|M.gilvum_PYR-GCK ----------------------------GSPPAPG-APAAAAATFVPYVV Mvan_0415|M.vanbaalenii_PYR-1 ----------------------------GTAPAPG-APAAATASFVPYAV MAB_2254c|M.abscessus_ATCC_199 ----------------------------PSAPAPAPAPTAAGAGFAPYLV TH_3113|M.thermoresistible__bu ----------------------------PSLPSGSSAPPAPTGSAAPTTG MAV_0535|M.avium_104 ----------------------------GVAKAAEAVLPAAVPGAGLGSL MLBr_01182|M.leprae_Br4923 ----------------------------AVQSTGRGLLGSSSGG------ MSMEG_0868|M.smegmatis_MC2_155 ------------------------GGDGGNGGFGYVLIAGPNVTVGSETR MMAR_0641|M.marinum_M GNTGNGNIGIGLNGDGLQGFGGWNSGSGNIGLFNSGTDNVGIGNSGTGNS MUL_0965|M.ulcerans_Agy99 G----------------------NAGLLNTGSFNSGKFNTGDFNSGSMNT Mb0362c|M.bovis_AF2122/97 GLSGDNQQGFNFAG-------GWNSGTANIGLFNSGTNNVGIGNSGTGNW Rv0355c|M.tuberculosis_H37Rv GLSGDNQQGFNFAG-------GWNSGTANIGLFNSGTNNVGIGNSGTGNW Mflv_0325|M.gilvum_PYR-GCK AGRD---PYEGFSP--------TVRDSTGAKAPAGTIPAAASGIAASAAE Mvan_0415|M.vanbaalenii_PYR-1 AGRD---PGTGFSP--------TVRDSTSAKAPASGIPAAASGVAASAAE MAB_2254c|M.abscessus_ATCC_199 GAIPDEPPAIQFGP--------TLNEGNKAQAPASGISAAAA-AAASARS TH_3113|M.thermoresistible__bu TAPGGAGSPPPAGH--------SVPPAPHSAPPVGTSGPPYLIAAQPAPG MAV_0535|M.avium_104 GSLG------------------SIGGSVGKAASIGGLSVPASWASAAPTP MLBr_01182|M.leprae_Br4923 ----------------------HVTAQLGRAASIGSLRVPQTWTTASQPV MSMEG_0868|M.smegmatis_MC2_155 GGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHAIGGNG . : MMAR_0641|M.marinum_M GIGNTGSYNTGIGNVGVANTGLFNIGNLNTGIGNPGNYNSGAHNVGSTNT MUL_0965|M.ulcerans_Agy99 GYFNSSGHNTGLGNSGFTNTGFFNSGDLNTGMGSP--------------- Mb0362c|M.bovis_AF2122/97 GIGNSGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNT Rv0355c|M.tuberculosis_H37Rv GIGNSGSGNTGIGNTGSTNTGFFNTGIVNTGVANAGSYNTGWYNTGDTNT Mflv_0325|M.gilvum_PYR-GCK RRKRRRRQKEEIKGRGYADAYADYEELPDDGPPEQPA------------- Mvan_0415|M.vanbaalenii_PYR-1 RRKRRRRQKDEIAGRAYADAYADYEPEPDDEPPVRQE------------- MAB_2254c|M.abscessus_ATCC_199 RARRKRGARVKDPAPQYMDMNVTVDADYGE-PPGSAQ------------- TH_3113|M.thermoresistible__bu VARRSAGARRAASIVEPAGSAAAAAAARESAPIRRRRG------------ MAV_0535|M.avium_104 -----PSVAVALNGATTAGAAEHAASAVGGVPMMPAG------------- MLBr_01182|M.leprae_Br4923 TAATRALSPARVAVATESESAPLLGGGLPMAPMVPGG------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGG----------- MMAR_0641|M.marinum_M GGANQGDYNTGWLNLGDYNTGLANVGNVNTGALISGNYDNGILWRSDYRA MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GIANLGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQG Rv0355c|M.tuberculosis_H37Rv GIANLGDFNTGFYNTGNFSTGFANQGDIATGAFITGDMGNGAFWRGDQQG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M QGGFSYAIGLVPITTSLNLSVPIDIPISATVGNTVIEGFTIPEI------ MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 LFSAGYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTI Rv0355c|M.tuberculosis_H37Rv LFSAGYRVHVPEIPAHVTVEVPVNIPITASFTNTVYSGITLEQINFGFTI Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M PIGAYGVVSGNIGPETFPTITIVGPTIDIGVG--GTQSVFTPSFVVDTGL MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 DIAGIPLLAGAISKAVLPPITGTGPAITVNIGDPGGSTAIRIPATASVGP Rv0355c|M.tuberculosis_H37Rv DIAGIPLLAGAISKAVLPPITGTGPAITVNIGDPGGSTAIRIPATASVGP Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M VQAIVLDLPSGPGVGNSTSVESSGFFNSGDGSASGFGNGGGSNSGFLNFA MUL_0965|M.ulcerans_Agy99 ---------------EDQSVANSGFRNAGSG------------------- Mb0362c|M.bovis_AF2122/97 FDVTFVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGANISGFQNVA Rv0355c|M.tuberculosis_H37Rv FDVTFVNIAATTGFFNATTDPSSGFFNGGPGTVSGIANIGANISGFQNVA Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M TDSLGNSGFKNYGTLESGIANLGNSVSGVFNTSALDLLTAANVSGVSNFG MUL_0965|M.ulcerans_Agy99 -----NSGFNNTGSFSS--------------------------------- Mb0362c|M.bovis_AF2122/97 N--SATSGFNNYGSLQSGLANLGDTVSGVFNTG---IGAPANVSGMFNIG Rv0355c|M.tuberculosis_H37Rv N--SATSGFNNYGSLQSGLANLGDTVSGVFNTG---IGAPANVSGMFNIG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M SNLSGFFLAGDSADRIFNVGVANDGSFNIGSANLGDYNFGLGNVGNTNFG MUL_0965|M.ulcerans_Agy99 ----GFFNSTNSNSEFLNAG------------------------------ Mb0362c|M.bovis_AF2122/97 SNLAGFFHDQATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLG Rv0355c|M.tuberculosis_H37Rv SNLAGFFHDQATGMSMFNLGLGNIGQFNVGFSNVGDSNAGLANIGSFNLG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M PGNLGSTNIGGANIGDTNFGFGNIGANNFGFGNSGASLTDGNHNIGFGNT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 SGNLGSFNVFGGNQGSYNIGPANLGNYNIGLGNLG------SYNFGFGNA Rv0355c|M.tuberculosis_H37Rv SGNLGSFNVFGGNQGSYNIGPANLGNYNIGLGNLG------SYNFGFGNA Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M GSNNIGIGNTGDGNIGFGNTGNDNTGIGLNGDGLQGF---GGWNSGSGNI MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GDFNLGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNS Rv0355c|M.tuberculosis_H37Rv GDFNLGFANTGNNNIGFANTGNNNIGIGLSGDNQQGFNFAGGWNSGSGNS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M GVFNSGTDNVGIGNSGTGNSGIGNSGSYNTGIGNSGLANTGLFNSGSFNT MUL_0965|M.ulcerans_Agy99 ---------------GTVNSGINNSGNTNAGIGNLGDDNFGLFNNGTFNT Mb0362c|M.bovis_AF2122/97 GLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNT Rv0355c|M.tuberculosis_H37Rv GLFNSGTNNIGLFNSGTGNIGIGNSGTGNWGIANTGDTNTGIFNTGDVNT Mflv_0325|M.gilvum_PYR-GCK -----------------PRVTASTRGAGPMGFAGTVSRGD-EQAGGLTTL Mvan_0415|M.vanbaalenii_PYR-1 -----------------PRIAATERGAGPMGFAGTVSRDA-AQAGGLTTL MAB_2254c|M.abscessus_ATCC_199 -----------------RQSTASARGAGHLGLAGTSPKTT-ATAAGLVAR TH_3113|M.thermoresistible__bu -----------------QKDGLHGHRHEHQQPASMSAATA-PSAAGIRVL MAV_0535|M.avium_104 ---------------------AAGRGAGAHFVVPRYGFKP-TVIAQPPAG MLBr_01182|M.leprae_Br4923 -----------------------GSGTGGVNTALRLQPRAFVMPRNPAAG MSMEG_0868|M.smegmatis_MC2_155 --------------DGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGR MMAR_0641|M.marinum_M GIGNVGSYNTGTFNVGDHNTGNFNTGQSNTGSLNVGDLNTGWANTGNVNT MUL_0965|M.ulcerans_Agy99 GAG-----NSSGGAVFPYTSGLFNSGNGSSGVFNAGDEQSGFFGT----- Mb0362c|M.bovis_AF2122/97 GLLNAGNVNTGIFNTGHYNTGSFNAGSFNTAGFNPGSYNTGYLNTGSYNT Rv0355c|M.tuberculosis_H37Rv GLLNAGNVNTGIFNTGHYNTGSFNAGSFNTAGFNPGSYNTGYLNTGSYNT Mflv_0325|M.gilvum_PYR-GCK A-----GDSFGGGPREPMLPGTWDPDATDDRHTDGRDGHDGHDGKEKP-- Mvan_0415|M.vanbaalenii_PYR-1 P-----GDPFGGGPKAPMLPGTWDPDTEPD------ERHNHHDGKDSQ-- MAB_2254c|M.abscessus_ATCC_199 GSAGSDTDVPETARIVPMIPTTWSTDSDEAID------------------ TH_3113|M.thermoresistible__bu GGAGRISRTRGSVPHAEITPGDPTEPSSPT--------DRAHRPAEPN-- MAV_0535|M.avium_104 G------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGT MMAR_0641|M.marinum_M GALISGDYNNGLLWRGDYQG---NLGAFNYTVTVPTTTADLNLSFPISLP MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GLANSGDVNTGGFITGNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKLH Rv0355c|M.tuberculosis_H37Rv GLANSGDVNTGGFITGNYSNGFWWRGDYQGLAGISQTITVPDTAVPVKLH Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SWVQAGYGPTTG-------------GKASGTAKAGHGGKASDGGKGGNGG MMAR_0641|M.marinum_M ISIDIGKIVIESFTLPKITANLDGKIKYKIPGVGKVNVKLYWDLKISPIT MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 VPIFLDIPVTGTLGTFTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNI Rv0355c|M.tuberculosis_H37Rv VPIFLDIPVTGTLGTFTVHGFRFPEITGDIFLIGIPFNAATLDAFSFPNI Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITD MMAR_0641|M.marinum_M FSDITISGPTLTSTIGNTDGSTVLGVDTDGTIGPLTIPLIDIPAGPGFGN MUL_0965|M.ulcerans_Agy99 ------SGLVLTGTDG------LAATTTSG------LPALDLPAP----- Mb0362c|M.bovis_AF2122/97 SIVLPNIGINLGSGPD-----PLIDIAGTGGLLPIKIPLIDIPAAPGFGN Rv0355c|M.tuberculosis_H37Rv SIVLPNIGINLGSGPD-----PLIDIAGTGGLLPIKIPLIDIPAAPGFGN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKG--KAAGGNGG MMAR_0641|M.marinum_M SSTSPSSGFFNSGDGSSSGFGNVGINNSGFFNVSF-IDGNSGLRNYGNLE MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 STTTPSSGFFNAGTGTVSGVGNVGSNSSGFFDLTSGSSGISGVQNFGELI Rv0355c|M.tuberculosis_H37Rv STTTPSSGFFNAGTGTVSGVGNVGSNSSGFFNLTSGSSGISGVQNFGELI Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTF MMAR_0641|M.marinum_M SGLGNLGNSISGLLNTSTLDIDTPAVVSGIGNIGTNLSGFYNDASGNAPD MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 SGGFNFGNTVSGLVNASTLGLSMPANLSGGGNVGATVAGFVNN------T Rv0355c|M.tuberculosis_H37Rv SGGFNFGNTVSGLVNASTLGLSMPANLSGGGNVGATVAGFVNN------T Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 VNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGL MMAR_0641|M.marinum_M STFNLGFADIGIFNAGAANTGNYNLGFGNIGDGNVGAANVGNFNFGGANI MUL_0965|M.ulcerans_Agy99 -----------------------NLGIGNAGVGNLGLGNIGDYNLGSGNT Mb0362c|M.bovis_AF2122/97 QILNLGFGNVGSGNVGHGNIGDSNVGLGNLGNANVGHGNIGSFNVFSGNR Rv0355c|M.tuberculosis_H37Rv QILNLGFGNVGSGNVGHGNIGDSNVGLGNLGNANVGHGNIGSFNVFSGNR Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNG-TATGTA MMAR_0641|M.marinum_M GDTNFGFGNIGNNNFGFGNSGASLTNGNHNIGFGNTGSNNFGFGNTGDGN MUL_0965|M.ulcerans_Agy99 GDANFGSGNIG--------------------------ALNLGSGNHGDAN Mb0362c|M.bovis_AF2122/97 GSYNIGPANLGNYNIGLGNLG------SYNFGFGNAGDFNLGFANSGSNN Rv0355c|M.tuberculosis_H37Rv GSYNIGPANLGNYNIGLGNLG------SYNFGFGNAGDFNLGFANSGSNN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNG MMAR_0641|M.marinum_M IGFGNTGDGNIGIGLSGDGLRGFGALNTGSGNVGLFNSGTNNIGLFNSGS MUL_0965|M.ulcerans_Agy99 LGFGNTGDN----------------------NIGLFNSGDNNVGFFNSGG Mb0362c|M.bovis_AF2122/97 IGFANTGNNNIGIGLSGHNQQGFGSWNSGTANTGLFNSGTNNIGLFNSGT Rv0355c|M.tuberculosis_H37Rv IGFANTGNNNIGIGLSGHNQQGFGSWNSGTANTGLFNSGTNNIGLFNSGT Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQ MMAR_0641|M.marinum_M DNIGIGNSGIGNAGLFNSGNYDTGMFNAGIVNTGIG-------------- MUL_0965|M.ulcerans_Agy99 ANFGLANSGDTNTGLWNAGSTNTGFGNAGSADFGFG-------------- Mb0362c|M.bovis_AF2122/97 GNIGIGNSGIGNTGIGNPGVGNTGLGNSGTGNWGLWNPGTGNMGVANVGT Rv0355c|M.tuberculosis_H37Rv GNIGIGNSGIGNTGIGNPGVGNTGLGNSGTGNWGLWNPGTGNMGVANVGT Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSA MMAR_0641|M.marinum_M -NAGDFNTGTFNAGDANTGNANSGSYNTGG---------------FNSGN MUL_0965|M.ulcerans_Agy99 -NAGDRNMGFGNAGAANMGAGNSGSYNTGS---------------FNSG- Mb0362c|M.bovis_AF2122/97 YNTGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNTGD Rv0355c|M.tuberculosis_H37Rv YNTGGYNVGSTNTGIANVGIANTGSYNTGSTNTGSFNDGDFNTGFYNTGD Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TGTATGGDGGKATGTASQGGNGGPSWVQSG-------------------- MMAR_0641|M.marinum_M YDTGWANTGDVDTGIFISGNYSNGILARGDYQ------------------ MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 YNTGFYNTGDVNTGAFIGGNFSNGAFWQSDHQGQWGAHYAITVPQIPLLN Rv0355c|M.tuberculosis_H37Rv YNTGFYNTGDVNTGAFIGGNFSNGAFWQSDHQGQWGAHYAITVPQIPLLN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ------------YGSTLGGN------------------------------ MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 FSLNIPVNIPIHLDFGTLAVNGFQIPAITLRALGVTHFSVGPIIVPRIAG Rv0355c|M.tuberculosis_H37Rv FSLNIPVNIPIHLDFGTLAVNGFQIPAITLRALGVTHFSVGPIIVPRIAG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M --------------------------GLVGVPLFDIAAAPGFGNTTTSYS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 TLPVIDINIGDPGGSSSIPITITSGAGPVVIPLLDIPPAPGFGNSTTGPS Rv0355c|M.tuberculosis_H37Rv TLPVIDINIGDPGGSSSIPITITSGAGPVVIPLLDIPPAPGFGNSTTGPS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M SGFFNNGAGSGSGFFNSGTDVSGYG-------------NLGAVQSGLANY MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 SGFFNSGTGSSSGFGNVGANNSGFWNTAFAGIGNSGLQNFGSLQSGWANL Rv0355c|M.tuberculosis_H37Rv SGFFNSGTGSSSGFGNVGANNSGFWNTAFAGIGNSGLQNFGSLQSGWANL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M GNSVSGLFNTSSLDTATAAYVSGVGNAGANLAGLFRDSAGGTT------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 GNTVSGFYNTSAADFATPANLSGLSNVGADLTGVLRGPNGSTFNAGLANL Rv0355c|M.tuberculosis_H37Rv GNTVSGFYNTSAADFATPANLSGLSNVGADLTGVLRGPNGSTFNAGLANL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M --LNVGFANLGVLNLG-----AANVGDYNVGTANVGGINFGGANIGDLNF MUL_0965|M.ulcerans_Agy99 -----------TLNTG-----DFNGGDHNTGWGNSGNTNTGGINSGDLNT Mb0362c|M.bovis_AF2122/97 GQFNVGSANLGSANLG-----SANLGNSNVGFGNIGNANIGGANIGDFNV Rv0355c|M.tuberculosis_H37Rv GQFNVGSANLGSANLGSANLGSANLGNSNVGFGNIGNANIGGANIGDFNV Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------ATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTAT MMAR_0641|M.marinum_M GAGNLGSTNFGFGNLGSNNFGFGNSGVSLANGNHNFGFGNTGSNNF---- MUL_0965|M.ulcerans_Agy99 GFG-----------------------SSADQAVTNSGFGNNGSGNS---- Mb0362c|M.bovis_AF2122/97 GIANTGPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGL Rv0355c|M.tuberculosis_H37Rv GIANTGPGLTAAVNNIGIGNTGNYNIGVGNTGNYNIGFGNTGNNNIGIGL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHG----------- MMAR_0641|M.marinum_M --------------------------------------GFGNTGDGNIGF MUL_0965|M.ulcerans_Agy99 --------------------------------------GFNNTGDTNSGF Mb0362c|M.bovis_AF2122/97 SGDNQIGFGPLNAGIANMGLFNLGDNNFGMANAGNFNQGIANTGNNNIGL Rv0355c|M.tuberculosis_H37Rv SGDNQIGFGPLNAGIANMGLFNLGDNNFGMANAGNFNQGIANTGNNNIGL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 --------------------------------------GAGNGGNGGKGA MMAR_0641|M.marinum_M GNTGDGNIGIGLNGDGLRGFEALNSGTDNV-------------------- MUL_0965|M.ulcerans_Agy99 HNANTS---------------ALFSGHS---------------------- Mb0362c|M.bovis_AF2122/97 FNTGNNNVGIGLTGDGLSGFSSLNSGAGNTGFFNSGTANTGLFNSGTGNT Rv0355c|M.tuberculosis_H37Rv FNTGNNNVGIWLTGDGLSGFSSLNSGAGNTGFFNSGTANTGLFNSGTGNT Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DGWVQAYDPAGPVGSKIANSSAVAG------------------------- MMAR_0641|M.marinum_M ------------------------------------------GLFNSGTG MUL_0965|M.ulcerans_Agy99 ------------------------------------------GLLNAG-- Mb0362c|M.bovis_AF2122/97 GLFNSGTGNVGIGNMGTGGFGVGLSGDSQVGIGGTNSGSFNIGLFNSGTG Rv0355c|M.tuberculosis_H37Rv GLFNSGTGNVGIGNMGTGGFGVGLSGDSQVGIGGTNSGSFNIGLFNSGTG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M NVGIGNSGTGNWGIGNSGNYNTGVGNTGAANTGMFNSGIANTGVANAGSY MUL_0965|M.ulcerans_Agy99 -----------------GSQSVGINNTGSFNTVLFNTGFRTAGIANSATN Mb0362c|M.bovis_AF2122/97 NVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAGLVNTGIANPGNH Rv0355c|M.tuberculosis_H37Rv NVGIGNSGTGNVGIGNTGTGNTGIGNSGNYNTGLLNAGLVNTGIANPGNH Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------NGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGN MMAR_0641|M.marinum_M NTGNLNAGDINTGSFNTGVSNTGYFNVGDTNTGIANLGDINTGGFNSGSM MUL_0965|M.ulcerans_Agy99 --GLLTA-----------------------TSGVANSGNNSSGGFN---- Mb0362c|M.bovis_AF2122/97 NTGLFNIGTFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSM Rv0355c|M.tuberculosis_H37Rv NTGLFNIGTFNTGIANPGHYNTGSYNTGSYNTGMANAGDYGTGAFITGSM Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADG MMAR_0641|M.marinum_M NNGFLLRGDELGQLGFNYTLNIPTLPVDLDIYANFQTPISLDVGGTTIHS MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 NNGLLWRADRQGLLAANYTITIERPAAFLNVDIPVNIPITGDITNVSIPA Rv0355c|M.tuberculosis_H37Rv NNGLLWRADRQGLLAANYTITIERPAAFLNVDIPVNIPITGDITNVSIPA Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TPGTAGTTGANNP------------------------------------- MMAR_0641|M.marinum_M FDISAFTISGKYGY-----SYKVLGIKFNYPFKYSFDIPAITIPSIQIGG MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 ITFPRIDASGSVDIGILSGTVLAPVGPITLHGGDASAPLDTPIEIDFGPS Rv0355c|M.tuberculosis_H37Rv ITFPRIDASGSVDIGILSGTVLAPVGPITLHGGDASAPLDTPIEIDFGPS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M SSQNFTVGPPALNTTINFDGGP-----LNIAVDMDPAPGFFNFTNNDSSG MUL_0965|M.ulcerans_Agy99 -------------------------------------------ANPDQSG Mb0362c|M.bovis_AF2122/97 PAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLRPAPGFFNATTGPSSG Rv0355c|M.tuberculosis_H37Rv PAINLNIGKPDGSTVINIVGGAGAGPISIPIIDLRPAPGFFNATTGPSSG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M FFNSGKGFTSGLGNIGGYDSGFLNGSMDPFGSGSSQTSGVYNFGELQSGL MUL_0965|M.ulcerans_Agy99 FFN----------------------------------------------- Mb0362c|M.bovis_AF2122/97 FLNWGAGSASGLLNFG-NNSGLYN-----FATSSMGNSGFQNYGSLQSGW Rv0355c|M.tuberculosis_H37Rv FLNWGAGSASGLLNFG-NNSGLYN-----FATSSMGNSGFQNYGSLQSGW Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M VNVGNTVSGFFNTSKVKDAAAYISGFFNTGSNLSGFFNTGTGP------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 ANLGNSISGIYNTG--LGAPANVSGLLNIGTNLAGWLQNGPTETTFSVGL Rv0355c|M.tuberculosis_H37Rv ANLGNSISGIYNTG--LGAPANVSGLLNIGTNLAGWLQNGPTETTFSVGL Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 ANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGS Rv0355c|M.tuberculosis_H37Rv ANLGFWNLGSANIGNYNLGSANIGVYNLGSANIGDFNLGSANIGDFNLGS Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 ANIGSSNIGFGNVGPGLTAAIGNIGFGNTGNGNIGIGNTGTGNIGFGNTG Rv0355c|M.tuberculosis_H37Rv ANIGSSNIGFGNVGPGLTAAIGNIGFGNTGNGNIGIGNTGTGNIGFGNTG Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 NGNIGIGLTGDTMTGFGGWNSGTGNIGLFNSGTGNIGFGNSGTGNWGIGN Rv0355c|M.tuberculosis_H37Rv NGNIGIGLTGDTMTGFGGWNSGTGNIGLFNSGTGNIGFGNSGTGNWGIGN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 SGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSFN Rv0355c|M.tuberculosis_H37Rv SGDYNTGIGNTGSTNSGFFNTGLVNTGIGNSGDYNTGLFNAGNTNTGSFN Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 PGDYNTGGFNPGNYNTGYFNPGNSNTGFANSGDVNTGAFNSGNYSNGFFW Rv0355c|M.tuberculosis_H37Rv PGDYNTGGFNPGNYNTGYFNPGNSNTGIANSGDVNTGAFNSGNYSNGFFW Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 RGDYQGLGGFAYQSAVSEIPWSYDIGSNIEIPIEGDINAITQDAFTIDEF Rv0355c|M.tuberculosis_H37Rv RGDYQGLGGFAYQSAVSEIPWSYDRFQH---------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 EIPIKLRVSVCVIYIPFKGCVKHVSVTIPITTEHLGPYEIDASTINPDQP Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 IDTAFTQTLDFAGSGTVGAFPFGFGWQQSPGFFNSTTTPSSGFFNSGAGG Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M -------------------------------------------------- MUL_0965|M.ulcerans_Agy99 -------------------------------------------------- Mb0362c|M.bovis_AF2122/97 ASGFLNDAAAAVSGLGNVFTETSGFFNAGGVGNSGFQNFGNLLSGWANLG Rv0355c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_0325|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_2254c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3113|M.thermoresistible__bu -------------------------------------------------- MAV_0535|M.avium_104 -------------------------------------------------- MLBr_01182|M.leprae_Br4923 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0641|M.marinum_M ---------------------------------------- MUL_0965|M.ulcerans_Agy99 ---------------------------------------- Mb0362c|M.bovis_AF2122/97 NTVSGFYNTSMLDLATQALISGFGNHGARLSGILNNGSGP Rv0355c|M.tuberculosis_H37Rv ---------------------------------------- Mflv_0325|M.gilvum_PYR-GCK ---------------------------------------- Mvan_0415|M.vanbaalenii_PYR-1 ---------------------------------------- MAB_2254c|M.abscessus_ATCC_199 ---------------------------------------- TH_3113|M.thermoresistible__bu ---------------------------------------- MAV_0535|M.avium_104 ---------------------------------------- MLBr_01182|M.leprae_Br4923 ---------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ----------------------------------------