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MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVLLDLMLPGMSGTDVCKQLRAR SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDDSEVSDGVLESGPVRMDV ERHVVSVNGDAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVKRLRSKIEADPA NPVHLVTVRGLGYKLEG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0816 | regX3 | - | 100% (227) | two-component sensory transduction protein RegX3 |
| M. marinum M | MMAR_1299 | mtrA | 8e-57 | 49.32% (221) | two-component sensory transduction transcriptional |
| M. marinum M | MMAR_4455 | trcR | 2e-44 | 39.91% (223) | two-component transcriptional regulator TrcR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0501 | regX3 | 1e-124 | 98.68% (227) | two component sensory transduction protein RegX3 |
| M. gilvum PYR-GCK | Mflv_0082 | - | 1e-117 | 93.86% (228) | two component transcriptional regulator |
| M. tuberculosis H37Rv | Rv0491 | regX3 | 1e-124 | 98.68% (227) | two component sensory transduction protein RegX3 |
| M. leprae Br4923 | MLBr_02439 | - | 1e-105 | 96.95% (197) | putative two-component system response regulator |
| M. abscessus ATCC 19977 | MAB_4047c | - | 1e-116 | 91.67% (228) | sensory transduction protein RegX3 |
| M. avium 104 | MAV_4660 | - | 1e-123 | 98.24% (227) | DNA-binding response regulator |
| M. smegmatis MC2 155 | MSMEG_0937 | regX3 | 1e-116 | 94.22% (225) | DNA-binding response regulator RegX3 |
| M. thermoresistible (build 8) | TH_4312 | - | 1e-113 | 89.04% (228) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_4560 | regX3 | 1e-125 | 100.00% (227) | two component sensory transduction protein RegX3 |
| M. vanbaalenii PYR-1 | Mvan_0831 | - | 1e-118 | 93.86% (228) | two component transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0082|M.gilvum_PYR-GCK MTSVLIVEDEESLADPLAFLLRKEGFETTVVTDGPSALAEFERAGADIVL
Mvan_0831|M.vanbaalenii_PYR-1 MTSVLIVEDEESLADPLAFLLRKEGFEATVVADGPSALAEFERAGADIVL
Mb0501|M.bovis_AF2122/97 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVL
Rv0491|M.tuberculosis_H37Rv MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVL
MAV_4660|M.avium_104 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGSAALAEFDRAGADIVL
MMAR_0816|M.marinum_M MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVL
MUL_4560|M.ulcerans_Agy99 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRSGADIVL
MLBr_02439|M.leprae_Br4923 -----------------------------MVTDGPAALAEFDRSGADIVL
MSMEG_0937|M.smegmatis_MC2_155 ---MLIVEDEESLADPLAFLLRKEGFEATVVGDGPSALAEFERSGADIVL
MAB_4047c|M.abscessus_ATCC_199 MTSVLIVEDEDSLADPLAFLLRKEGFEATIVNDGPSALAEFERAGADIVL
TH_4312|M.thermoresistible__bu MTSVLIVEDEESLADPLAFLLRKEGFETTIVTDGPSALAEFERSGADIIL
:* **.:*****:*:****:*
Mflv_0082|M.gilvum_PYR-GCK LDLMLPGMSGTDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVT
Mvan_0831|M.vanbaalenii_PYR-1 LDLMLPGMSGTDVCKQLRSRSSVPVIMVTARDSEIDKVVGLELGADDYVT
Mb0501|M.bovis_AF2122/97 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
Rv0491|M.tuberculosis_H37Rv LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MAV_4660|M.avium_104 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MMAR_0816|M.marinum_M LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MUL_4560|M.ulcerans_Agy99 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MLBr_02439|M.leprae_Br4923 LDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEIDKVVGLELGADDYVT
MSMEG_0937|M.smegmatis_MC2_155 LDLMLPGMSGTDVCKQLRARSSVPVIMVTARDSEIDKVVGLELGADDYVT
MAB_4047c|M.abscessus_ATCC_199 LDLMLPGMSGTDVCKQLRAKSSVPVIMVTARDSEIDKVVGLELGADDYVT
TH_4312|M.thermoresistible__bu LDLMLPGMSGTDVCRRLRAKSKVPVIMVTARDSEIDKVVGLELGADDYVT
************* ::** :*.****************************
Mflv_0082|M.gilvum_PYR-GCK KPYSARELIARIRAVLRRGADADDLGVADGVLEAGPVRMDVERHVVSVNG
Mvan_0831|M.vanbaalenii_PYR-1 KPYSARELIARIRAVLRRGSDADDAGIGDGVLEAGPVRMDVERHVVSVNG
Mb0501|M.bovis_AF2122/97 KPYSARELIARIRAVLRRGGD-DDSEMSDGVLESGPVRMDVERHVVSVNG
Rv0491|M.tuberculosis_H37Rv KPYSARELIARIRAVLRRGGD-DDSEMSDGVLESGPVRMDVERHVVSVNG
MAV_4660|M.avium_104 KPYSARELIARIRAVLRRGGD-DDSEISDGVLESGPVRMDVERHVVSVNG
MMAR_0816|M.marinum_M KPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRMDVERHVVSVNG
MUL_4560|M.ulcerans_Agy99 KPYSARELIARIRAVLRRGGD-DDSEVSDGVLESGPVRMDVERHVVSVNG
MLBr_02439|M.leprae_Br4923 KPYSARELIARIRAVLRRGGD-DDSEISDGVLESGPLRMDVERHVVSVNG
MSMEG_0937|M.smegmatis_MC2_155 KPYSARELIARIRAVLRRGADNDDAGADDGVLEAGPVRMDVERHVVSVNG
MAB_4047c|M.abscessus_ATCC_199 KPYSARELIARIRAVLRRGSDSEETASGDGVLEAGPVRMDVDRHTVSVNG
TH_4312|M.thermoresistible__bu KPYSARELIARIRAVLRRGSDLDGADVDDSVLEAGPVRMDVDRHVVTVRG
*******************.* : *.***:**:****:**.*:*.*
Mflv_0082|M.gilvum_PYR-GCK APITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
Mvan_0831|M.vanbaalenii_PYR-1 QSITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
Mb0501|M.bovis_AF2122/97 DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
Rv0491|M.tuberculosis_H37Rv DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MAV_4660|M.avium_104 DTITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MMAR_0816|M.marinum_M DAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MUL_4560|M.ulcerans_Agy99 DAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MLBr_02439|M.leprae_Br4923 YAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGVDYVGDTKTLDVHVK
MSMEG_0937|M.smegmatis_MC2_155 EPITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
MAB_4047c|M.abscessus_ATCC_199 EAITLPLKEFDLLEYLIRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
TH_4312|M.thermoresistible__bu EPITLPLKEFELLEYLLRNSGRVLTRGQLIDRVWGADYVGDTKTLDVHVK
.********:*****:******************.**************
Mflv_0082|M.gilvum_PYR-GCK RLRSKIESDPANPVHLVTVRGLGYKLEG
Mvan_0831|M.vanbaalenii_PYR-1 RLRSKIEADPANPVHLVTVRGLGYKLEG
Mb0501|M.bovis_AF2122/97 RLRSKIEADPANPVHLVTVRGLGYKLEG
Rv0491|M.tuberculosis_H37Rv RLRSKIEADPANPVHLVTVRGLGYKLEG
MAV_4660|M.avium_104 RLRSKIEADPANPVHLVTVRGLGYKLEG
MMAR_0816|M.marinum_M RLRSKIEADPANPVHLVTVRGLGYKLEG
MUL_4560|M.ulcerans_Agy99 RLRSKIEADPANPVHLVTVRGLGYKLEG
MLBr_02439|M.leprae_Br4923 RLRSKIEADPANPVHLVTVRGLGYKLES
MSMEG_0937|M.smegmatis_MC2_155 RLRSKIEEDPANPVHLVTVRGLGYKLEG
MAB_4047c|M.abscessus_ATCC_199 RLRSKIEADPANPVHLVTVRGLGYKLEG
TH_4312|M.thermoresistible__bu RLRSKIEEDPANPVHLVTVRGLGYKLEG
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