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VSFVNVTPEAVAAAASDLTGIGSVLGEANAVAARATTTVLAAGGDEVSAAIAALFSFHGQSYQTLGAQAE AFHAQFAQLMANGAGTYASAEAANAAPFQGLLGAVNAPVQTLTGRPLIGNGANGAPGTGANGGAGGWLIG NGGAGGSGAPGLNGGAGGAAGLIGTGGAGGAGGSSSTVNGGVGGTGGAGGWLLGNGGAGGAGGASAIPLG PDLIGKGGAGGAGGSGGLFGAGGLGGAGGFGGSAGGAGGQGGAGGLLSGLVGAGGGHGGTGGYGGGAGGA GGNAGLLAGTGGSGGTGGYGGGAGGAGGNAGLLFGNGGAGGAGATGGGNTGGIGGDGGNAGMLFSNGGAG GAGGASELADGGAGGAGGNGGWLLSNGGVGGAGGAGADAVGPPFGIPAGSGGNGGAGGAGGVFFGNGGAG GAGGTGGDGGGIGGAGGAAGNGVLIGNGGNGGIGGIGLTPGADGIGGTSGLVLGLDGFNAPASTSPLHTL QQQALNAINAPVEAATGRPLIGNGTPGAAGSGADGTAGGWLLGDGGAGGSSTAGSGLDGGTGGAAGLWGT GGTGGAGGSGGTDSISGIAGGDGGAGGAGGWLSGTGGAGGSGGAGGDGGVLGSGDGGAGGAGGSGGAGGL LGAGGTGGTGAIGGFSGLLASGDGGAGGAGGAGGAGGLLGGLVGAGGGDGGAGGTGGFHGDAVTGTAGAG GTGGAGGDAGLLGGPGGAGGTGGTGGPNIDAGGVLGAPGNSGAGGAGGNAGTLFGSGGVGGDGGSGHGNG GDGGGGGNAGLLFSDAGGGGFGGFGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGDAGAGGAGGTSGQ LLGDGGAGGAGGEAELAAGGAGGSGGVGGDAVLIGAGGNGGNGGPGTAKGDPGSGGAGGPLGVDGLNGLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4398 | - | - | 100% (910) | PE-PGRS family protein, PE_PGRS9_3 |
| M. marinum M | MMAR_4399 | - | 0.0 | 72.49% (927) | PE-PGRS family protein |
| M. marinum M | MMAR_1391 | - | 0.0 | 64.62% (927) | PE-PGRS family protein, PE_PGRS9 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0767 | PE_PGRS9 | 0.0 | 57.27% (929) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-163 | 47.07% (820) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv0746 | PE_PGRS9 | 0.0 | 59.01% (905) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 35.87% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-44 | 32.06% (499) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 7e-24 | 48.17% (164) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-129 | 38.04% (1070) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-38 | 41.78% (304) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3062 | - | 0.0 | 60.66% (933) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-157 | 45.54% (808) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0767|M.bovis_AF2122/97 --------------------------------------------------
Rv0746|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4398|M.marinum_M --------------------------------------------------
MUL_3062|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 --------------------MSFVLAMPEVLGSAATDLAALG--------
Rv0746|M.tuberculosis_H37Rv --------------------MSFVLAMPEVLGSAATDLAALG--------
MMAR_4398|M.marinum_M --------------------MSFVNVTPEAVAAAASDLTGIG--------
MUL_3062|M.ulcerans_Agy99 --------------------MAFVLAVPDMVAEAAADLAGVG--------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------MSIIDFILNLFRDPVEAASYVADPEAALAN---
MAV_4827|M.avium_104 --------------------MNIVLGVSMAPSSIQMVVLEGEYADG----
Mb0767|M.bovis_AF2122/97 ----------------------------------SVLGAADAAAAATTTG
Rv0746|M.tuberculosis_H37Rv ----------------------------------SVLGAADAAAAATTTG
MMAR_4398|M.marinum_M ----------------------------------SVLGEANAVAARATTT
MUL_3062|M.ulcerans_Agy99 ----------------------------------SVIDAANTAAAGSTTG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------AGLSAVSAAQVGAVMP
MAV_4827|M.avium_104 ----------------------------------ATVEEDAIDVTGADDA
Mb0767|M.bovis_AF2122/97 IVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA
Rv0746|M.tuberculosis_H37Rv IVAAAQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYA
MMAR_4398|M.marinum_M VLAAGGDEVSAAIAALFSFHGQSYQTLGAQAEAFHAQFAQLMANGAGTYA
MUL_3062|M.ulcerans_Agy99 IVAAAEDEVSAAIAALFSGHGQAYQQISTRVAEFHAQFERVFAAGVQAYS
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MAV_4827|M.avium_104 ATASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAAR
Mb0767|M.bovis_AF2122/97 S------------------------AEAAGAAVLANPAQSVQQDLLAAVN
Rv0746|M.tuberculosis_H37Rv S------------------------AEAAGAAVLANPAQSVQQDLLAAVN
MMAR_4398|M.marinum_M S------------------------AEAANAAPFQG--------LLGAVN
MUL_3062|M.ulcerans_Agy99 G------------------------AEAANASFLQDP----LQTALNATN
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 P----------------------------------------RDNDFLSHN
MAV_4827|M.avium_104 R--------------------------------------------IDNVM
Mb0767|M.bovis_AF2122/97 AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
Rv0746|M.tuberculosis_H37Rv AQSVALTGRPLIGNGANGAPG-----TGANGAPGGWLLGNGGAGGSAAAG
MMAR_4398|M.marinum_M APVQTLTGRPLIGNGANGAPG-----TGANGGAGGWLIGNGGAGGSGAP-
MUL_3062|M.ulcerans_Agy99 KPVQDLTGRPLVGNGANGVPG-----TGANGAAGGWLLGNGGAGGSGAA-
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 DTDFASHNPIASGNQVMSPSG-----NVDSFNRGPLLDLSFGDLQFGNRD
MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVY
Mb0767|M.bovis_AF2122/97 -SGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGG--AGGAGGSGGWLL
Rv0746|M.tuberculosis_H37Rv -SGLPGGAGGAAGLFGTGGAGGAGGSS---TVGDGE--AGGAGGSGGWLL
MMAR_4398|M.marinum_M --GLNGGAGGAAGLIGTGGAGGAGGSS---STVNGG--VGGTGGAGGWLL
MUL_3062|M.ulcerans_Agy99 --GQAGGDGGAAGLIGAGGAGGAGGNSPLRNTANGG--NGGTGGAGGLLF
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQ
MAV_4827|M.avium_104 KQQIRAESYGDAAGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQ
Mb0767|M.bovis_AF2122/97 GTGGVGGVGG-----LG---AGAGGAGGVGGAGGLLGAGGHGG-------
Rv0746|M.tuberculosis_H37Rv GTGGVGGVGG-----LG---AGAGGAGGVGGAGGLLGAGGHGG-------
MMAR_4398|M.marinum_M GNGGAGGAGGASAIPLGPDLIGKGGAGGAGGSGGLFGAGGLGG-------
MUL_3062|M.ulcerans_Agy99 GPGGVGGAGGAS--------FLTGGTGGDGGAGGLFGAGGLGG-------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGED--------AVGYGATGAAGAAGAAGAAGAAG-------
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGAD--------AVGYGATGAAGAAGAAGAAGKAG-------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGL--------FGLLGHSGSTGAAGAAGNGGDGGNGGFGYV
TH_3810|M.thermoresistible__bu IIS----------------------------LLSLAGNGGNGG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SQTRVGGDYTN---------VSGHGSADIDKSVTVVDDHSQRN-------
MAV_4827|M.avium_104 TTTFLDVSVAEE--------------PETALARGAALAAANAP-------
Mb0767|M.bovis_AF2122/97 ------AGGLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRG------
Rv0746|M.tuberculosis_H37Rv ------AGGLGAVTGGVGGTGGAGGLLAGLLAGPGGAGGTGGRG------
MMAR_4398|M.marinum_M ------AGGFGGSAGGAGGQGGAGGLLSGLVGAGGGHGGTGGYGGGAG--
MUL_3062|M.ulcerans_Agy99 ------VGGS-GNVGGNGGAGGAGGLLAGLVGAGGGDGGSGGLGAAGGDG
Mflv_5091|M.gilvum_PYR-GCK -------AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------
Mvan_1264|M.vanbaalenii_PYR-1 -------AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------
MSMEG_0868|M.smegmatis_MC2_155 LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA
TH_3810|M.thermoresistible__bu --------NGYRTTDNNALDGGHGG-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----TTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTSTS------
MAV_4827|M.avium_104 ------LFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVDPEPG------
Mb0767|M.bovis_AF2122/97 -------FLN--------------DGGVGGAGGNAG-----------LLF
Rv0746|M.tuberculosis_H37Rv -------FLN--------------NGGVGGAGGNAG-----------LLF
MMAR_4398|M.marinum_M GAGGNAGLLAGTGGSGGT---GGYGGGAGGAGGNAG-----------LLF
MUL_3062|M.ulcerans_Agy99 GNGGRAGLFGGAGGAGGMGATGGHSGGDGGAGGDAG-----------LLF
Mflv_5091|M.gilvum_PYR-GCK --------AVGAAGAAG------TVGTAGATGGTG---------------
Mvan_1264|M.vanbaalenii_PYR-1 --------AIGTAGVAG------AAGTAGATGGTG---------------
MSMEG_0868|M.smegmatis_MC2_155 NGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------AGGSAAVGGNAG--------------
MAV_4827|M.avium_104 ----------------------DDELAYSAVGEED---------------
Mb0767|M.bovis_AF2122/97 GAGGTGGSGGAGLGGDGGAG----------------GAGGNAGVLFGNAG
Rv0746|M.tuberculosis_H37Rv GAGGTGGSGGAGLGGDGGAG----------------GAGGNTGVLFGNAG
MMAR_4398|M.marinum_M GNGGAGGAGATGGGNTGGIG----------------GDGGNAGMLFSNGG
MUL_3062|M.ulcerans_Agy99 GTGGAGGAGGHAFDGDGGAG----------------GAGGNAGLMFSSGG
Mflv_5091|M.gilvum_PYR-GCK TGANGGAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGG
Mvan_1264|M.vanbaalenii_PYR-1 VGGNGGAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGG
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGG
TH_3810|M.thermoresistible__bu NGGNVGFFSLFNLGG--------------------AGGWGGSGVDG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAG-------------NAGLAGNAGLAGNAGL
MAV_4827|M.avium_104 AESPTVVIEKLFLPEDSEPR------------------RRPVLLVGSGLA
Mb0767|M.bovis_AF2122/97 SGGTGGFGD-TDGGAGGAGGDAGWLGS-GGVGGAGGFG------------
Rv0746|M.tuberculosis_H37Rv SGGTGGFGD-TDGGAGGAGGDAGWLGS-GGVGGAGGFG------------
MMAR_4398|M.marinum_M AGGAGGASELADGGAGGAGGNGGWLLSNGGVGGAGGAGADAVGPPFGI--
MUL_3062|M.ulcerans_Agy99 SGGVGGAGS-IDGGAGGAGGDAGWLGG-GGAGGAGGFG------------
Mflv_5091|M.gilvum_PYR-GCK AGGVGGQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---
Mvan_1264|M.vanbaalenii_PYR-1 VGGIGGQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---
MSMEG_0868|M.smegmatis_MC2_155 AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT
TH_3810|M.thermoresistible__bu -----------------VDVVGGNP-------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG------------
MAV_4827|M.avium_104 VVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPT------------
Mb0767|M.bovis_AF2122/97 --------------ETGDGGVGGAGGKAGLLIG-----------------
Rv0746|M.tuberculosis_H37Rv --------------ETGDGGVGGAGGKAGLLIG-----------------
MMAR_4398|M.marinum_M --------------PAGSGGNGGAGGAGGVFFG-----------------
MUL_3062|M.ulcerans_Agy99 --------------TISDGGAGGRGGGGGQLLG-----------------
Mflv_5091|M.gilvum_PYR-GCK ----------LQGGKGGDGGAGGKGGDADSMGS-----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------LQGGQGGDGGTGGTGGDATSMGE-----------------
MSMEG_0868|M.smegmatis_MC2_155 GGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG
TH_3810|M.thermoresistible__bu -----------------DGGTPG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------NAGLAGNAGLAGNAGLAGN-----------------
MAV_4827|M.avium_104 --------------EQAPAPPPVQASAPQPKIS-----------------
Mb0767|M.bovis_AF2122/97 ----NGGAGGAG--------------------------------------
Rv0746|M.tuberculosis_H37Rv ----NGGAGGAGGQGAVTGGTGGAG-------------------------
MMAR_4398|M.marinum_M ----NGGAGGAGGTGGDGGGIGGAGGAA----------------------
MUL_3062|M.ulcerans_Agy99 ----NGGAGGAGGQGGNDGGAGGLG-------------------------
Mflv_5091|M.gilvum_PYR-GCK -AGATGGKGGNGGNGGRGGLFG---------------KGGNAGNGAD---
Mvan_1264|M.vanbaalenii_PYR-1 -AGATGGKGGNGGNGGRGSLFG---------------RGGNAGNGGN---
MSMEG_0868|M.smegmatis_MC2_155 AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV
TH_3810|M.thermoresistible__bu ---AHGESHTPGVYTDRQ--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----AGLAGNAGLAGNAGLAGN---------------------------
MAV_4827|M.avium_104 ---VPEPVAAPKPLSPPVAAPLP---------------------------
Mb0767|M.bovis_AF2122/97 -----------------VLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGA
Rv0746|M.tuberculosis_H37Rv --------------GDGVLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGA
MMAR_4398|M.marinum_M --------------GNGVLIGNGGNGGIGGIGLTPGADGIGGTSGLVLGL
MUL_3062|M.ulcerans_Agy99 --------------GNGVLIGNGGNGGVGGVGETPGGDGGGGISGLLLGA
Mflv_5091|M.gilvum_PYR-GCK -------------------GGTGGAGGAGGTGG-TGGAGGTGG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GGTGGNGGNGGTGG-TGGNGGTGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKA
TH_3810|M.thermoresistible__bu -----------------------GEDGEDGTGTGIGGRGGNGG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------AGLAGNAGLAGNAAVAGNAAVAGN-------
MAV_4827|M.avium_104 ------------------AAPPPAAPPLPEAPPIPAAPPVVPVP------
Mb0767|M.bovis_AF2122/97 DG-----FNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVG
Rv0746|M.tuberculosis_H37Rv DG-----FNTPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVG
MMAR_4398|M.marinum_M DG-----FNAPASTSPLHTLQQQALNAINAPVEAATGRPLIGNGTPGAAG
MUL_3062|M.ulcerans_Agy99 DG-----FNAPAGSSPVHALQQQALAAINAPVQELTGRPLIGNGLPGSAG
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 NGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGG
TH_3810|M.thermoresistible__bu ---------SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGS
MLBr_01183|M.leprae_Br4923 -------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLT
MAB_4284c|M.abscessus_ATCC_199 --------AAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVG
MAV_4827|M.avium_104 --------VVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVR
Mb0767|M.bovis_AF2122/97 SGATGAPGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------L
Rv0746|M.tuberculosis_H37Rv SGATGAPGG--WLLGDGGAGGS--GAAGSGAPGGAGGAAG---------L
MMAR_4398|M.marinum_M SGADGTAGG--WLLGDGGAGGS--STAGSGLDGGTGGAAG---------L
MUL_3062|M.ulcerans_Agy99 SGAAGAPGG--WLLGDGGAGGS--AAATPGAAGGAGGAAG---------L
Mflv_5091|M.gilvum_PYR-GCK TGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GT
MSMEG_0868|M.smegmatis_MC2_155 HGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGA
TH_3810|M.thermoresistible__bu HGGNGGHGGRGGFLGIGGSG-------GWGGHGGNGGD-----------T
MLBr_01183|M.leprae_Br4923 TEIAPPAADDVSILLAHFFS-------------GHGRQ-----------Y
MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTGVGGGVSTG------VGVGSHVGGGISES---------L
MAV_4827|M.avium_104 VPQPPSPPQVGGTVPQSPPQ--------HQTPPGEGTPPK---------P
* *
Mb0767|M.bovis_AF2122/97 WGTGGAG----------------------GAGGWLLGDGGAGGIGGAS--
Rv0746|M.tuberculosis_H37Rv WGTGGAGGAGGS------SAGGGGAGGAGGAGGWLLGDGGAGGIGGAS--
MMAR_4398|M.marinum_M WGTGGTGGAGGSGGTDSISGIAGGDGGAGGAGGWLSGTGGAGGSGGAGGD
MUL_3062|M.ulcerans_Agy99 VGAGGAGGAGAN------------------TGISNPGFGGAGGAGGAG--
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAG------------DGTGGTGGTGG----TGGQGGQGGQGG-
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGAG------------DGLGGTGGTGG----TGGFGGQGGQGG-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGAGRIRVNNG-TATGTATGGNGGNGGNGDADGHRGGKGGDGGE
TH_3810|M.thermoresistible__bu DADGGNGGDG----------------GNGGSAG-----------------
MLBr_01183|M.leprae_Br4923 QAHASQG-------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSGSVGGSTAVG-------------------------------------
MAV_4827|M.avium_104 DGPGNYGGGHVP--------------------------------------
. .. *
Mb0767|M.bovis_AF2122/97 --------------TVLG-GTGGGGGVGGLWGAG----------------
Rv0746|M.tuberculosis_H37Rv --------------TVLG-GTGGGGGVGGLWGAG----------------
MMAR_4398|M.marinum_M -------------GGVLGSGDGGAGGAGGSGGAGG---------------
MUL_3062|M.ulcerans_Agy99 --------------AGAGGGVGEAGGAGGLLGAG----------------
Mflv_5091|M.gilvum_PYR-GCK ----------------TGGTGGQGG-LGGGGGTG----------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------------TGGTGGQGG-LGGVGGTG----------------
MSMEG_0868|M.smegmatis_MC2_155 ALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQ
TH_3810|M.thermoresistible__bu ----------------RGGTGGLRGVFGINGGNG----------------
MLBr_01183|M.leprae_Br4923 -------------------ATNHQDLIQSLLTSS----------------
MAB_4284c|M.abscessus_ATCC_199 ----------------GGAHTGVGGGVSTGVGVG----------------
MAV_4827|M.avium_104 ----------------TPGAGGSGGSGGGHVPTP----------------
. .
Mb0767|M.bovis_AF2122/97 ----------GAGGAGGTG--LVG-----------GDGGAGGAGGTG---
Rv0746|M.tuberculosis_H37Rv ----------GAGGAGGTG--LVG-----------GDGGAGGAGGTG---
MMAR_4398|M.marinum_M --------LLGAGGTGGTG--AIGGFSGLLASGDGGAGGAGGAGGAG---
MUL_3062|M.ulcerans_Agy99 ----------GTGGGGGVAPSLVDG----------GTGGAGGAGGAG---
Mflv_5091|M.gilvum_PYR-GCK -------GQGGTGGTGGQG----------------GTGGTGGTGGTG---
Mvan_1264|M.vanbaalenii_PYR-1 -------GTGGTGGTGGQG----------------GTGGTGGTGGTG---
MSMEG_0868|M.smegmatis_MC2_155 ASGTATDGHGGSGINGGHG----------------GNGGQGTIEANGPSA
TH_3810|M.thermoresistible__bu --------RAGLGGRGXXX----------------XGGGVGAAVRSG---
MLBr_01183|M.leprae_Br4923 -----------SAYAGTET------------------ANHDSL-------
MAB_4284c|M.abscessus_ATCC_199 -------SHVGGGISESLG----------------GSGSVGGSTAVG---
MAV_4827|M.avium_104 ----------GAGGSGGSG------------------GGHVPTPGTG---
. ..
Mb0767|M.bovis_AF2122/97 ---GLLAGLIGAGGGHGGTGGLN---------TNGDGGVGGAGGNAGMLA
Rv0746|M.tuberculosis_H37Rv ---GLLAGLIGAGGGHGGTGGLS---------TNGDGGVGGAGGNAGMLA
MMAR_4398|M.marinum_M ---GLLGGLVGAGGGDGGAGGTGGFHGDAVTGTAGAGGTGGAGGDAGLLG
MUL_3062|M.ulcerans_Agy99 ---GLFGGIFGAGGGDGGAGGFTG-------GIDGAGGVGGAGGNTGLLG
Mflv_5091|M.gilvum_PYR-GCK -----GTGGAGGDGGLGGLGGFGG-----SGGTGGQGGLGGPGGSTGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----GTGGAGGDGGLGGLGGFGG-----VGGTGGQGGQGGPGGSTGGAG
MSMEG_0868|M.smegmatis_MC2_155 VASGIGAGGNGGDGIDGGLGGNGG-----DGVVNTTANAANPGSATGTAT
TH_3810|M.thermoresistible__bu ------------NGVFSGGGGTPS-----AGFGVPTTIQFPAGSCTSRAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------GGAHTGVGGGVN-----TGVGVGSHVGGGISESLGGSG
MAV_4827|M.avium_104 -----------GPGGTGGSGG----------GHVPTPGAGTPGGSGGGHL
Mb0767|M.bovis_AF2122/97 GPGGAGGAGGDG-ENLDTG---------GDGGAGGSAGLLFGSGGAGGAG
Rv0746|M.tuberculosis_H37Rv GPGGAGGAGGDG-ENLDTG---------GDGGAGGSAGLLFGSGGAGGAG
MMAR_4398|M.marinum_M GPGGAGGTGGTGGPNIDAGGVLGAPGNSGAGGAGGNAGTLFGSGGVGGDG
MUL_3062|M.ulcerans_Agy99 GPGGSGGSGGDGIAKLGFN------VDGGAGGAGVNGGFLFGSGGTGGFG
Mflv_5091|M.gilvum_PYR-GCK GAGG--QAGTAGKGGLFG-----GSGSAGKAGATGAAGASGGKGAQGATG
Mvan_1264|M.vanbaalenii_PYR-1 GAGG--QAGVAGKGGLFG-----GSGSAGTAGVTGASGASGGKGAQGATG
MSMEG_0868|M.smegmatis_MC2_155 GGDGGKATGTASQGGNGGPSWV-QSGYGSTLGGNATGTATAGKGGEASNG
TH_3810|M.thermoresistible__bu SREG-------------------------IMPSSRAASARAG--------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SVGGSTAVG-------------------GGAHTSAINDALGGSGSVGGST
MAV_4827|M.avium_104 PFPG-----------------------AGSTPGGSGGGHLPTPG------
Mb0767|M.bovis_AF2122/97 GFGF---------------LGGDGGAGGNAGLLLSSGGAGGFG-------
Rv0746|M.tuberculosis_H37Rv GFGF---------------LGGDGGAGGNAGLLLSSGGAGGFG-------
MMAR_4398|M.marinum_M GSGHG--------------NGGDGGGGGNAGLLFSDAGGGGFG-------
MUL_3062|M.ulcerans_Agy99 GVGGVG---------TSTGIGGAGGRGGNAGLLFSDAGVGGFG-------
Mflv_5091|M.gilvum_PYR-GCK AQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-------
Mvan_1264|M.vanbaalenii_PYR-1 AQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-------
MSMEG_0868|M.smegmatis_MC2_155 GVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAA
TH_3810|M.thermoresistible__bu -------------------AACASSTSRSRRSFCCSRA------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AVGGG-----------AHTSAINESMNSSINASHSSSMNESFG-------
MAV_4827|M.avium_104 -------------------AGTPGGGLGGFGGGHAPAPGGGLG-------
Mb0767|M.bovis_AF2122/97 --------------GFGTAGG--VGGAGGNAGWLGFGGAGGIGGIGGNAN
Rv0746|M.tuberculosis_H37Rv --------------GFGTAGG--VGGAGGNAGWLGFGGAG----------
MMAR_4398|M.marinum_M --------------GFGLAGGGGTGGSGGDAGWLGSGGAGGAGGISVNGD
MUL_3062|M.ulcerans_Agy99 --------------GFG--------GTGGNAGWLGSGGSGGAGG-GSNGD
Mflv_5091|M.gilvum_PYR-GCK ----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------A
Mvan_1264|M.vanbaalenii_PYR-1 ----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------A
MSMEG_0868|M.smegmatis_MC2_155 IHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAV
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 GGAGGNGGTGGQLWGSGGAGGEG----------GAALSVGDTGGAGGVGG
Rv0746|M.tuberculosis_H37Rv ----------------------------------------------GVGG
MMAR_4398|M.marinum_M AGAGGAGGTSGQLLGDGGAGGAGG---------EAELAAGGAGGSGGVGG
MUL_3062|M.ulcerans_Agy99 GGAGGTGGSGGQIVGDGGAGGAGGQ--------GDLLAAGGSGGDGGQGG
Mflv_5091|M.gilvum_PYR-GCK AGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGG
Mvan_1264|M.vanbaalenii_PYR-1 AGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 AGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Mb0767|M.bovis_AF2122/97 SAGLIG--------TGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP
Rv0746|M.tuberculosis_H37Rv SAGLIG--------TGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP
MMAR_4398|M.marinum_M DAVLIG--------AGGNGGNGGPGTAKGDPGSGGAGG-PLGVDGLNGLS
MUL_3062|M.ulcerans_Agy99 DAVLIG--------TGGNGGNGASGVLAGIGGDGGSRGLLLGEDGVNGEA
Mflv_5091|M.gilvum_PYR-GCK AGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSG
Mvan_1264|M.vanbaalenii_PYR-1 DGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 DGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAE
MAV_4827|M.avium_104 ---------------GGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK--
Mb0767|M.bovis_AF2122/97 -------------------
Rv0746|M.tuberculosis_H37Rv -------------------
MMAR_4398|M.marinum_M -------------------
MUL_3062|M.ulcerans_Agy99 APPMTHIVLLGGDFPAAAS
Mflv_5091|M.gilvum_PYR-GCK GAAGDSDD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GAAGDSD------------
MSMEG_0868|M.smegmatis_MC2_155 GTTGANNP-----------
TH_3810|M.thermoresistible__bu -------------------
MLBr_01183|M.leprae_Br4923 -------------------
MAB_4284c|M.abscessus_ATCC_199 HH-----------------
MAV_4827|M.avium_104 -------------------