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TSMELMMPTDASFLFTESREHPMHVAGLQLFDPPDAAGPGFVDEIYRCLAANREGQPAFRKHPATLLGGI TNLGWQYDNEIDTDYHVRRSVLPYPGRVSELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFH HALLDGASALMLLQRALSDDPRDTEVRAPWNLPPQPDHAVGSSRLGSLANTAGSLMALGPSTVSLIRAAL VEQQLTLPFGAPRTLFNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQYLLEQNALP DAPLVALVPVSLRSQTDDSGGTMVGTVLCGLATDTTDPAKRLEMISQSMRRNKKAFSELSPLQAKALWAF NMAPLTLTAVPGFVPWTKPSFNVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSNAGTLEF GLVGCRRSVPHLQRLLLHLETSLHGLEQAVGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0529 | - | - | 100% (453) | hypothetical protein MMAR_0529 |
| M. marinum M | MMAR_5271 | - | e-174 | 66.52% (454) | hypothetical protein MMAR_5271 |
| M. marinum M | MMAR_1809 | - | e-153 | 60.22% (455) | hypothetical protein MMAR_1809 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3761c | - | 1e-172 | 65.86% (454) | hypothetical protein Mb3761c |
| M. gilvum PYR-GCK | Mflv_1058 | - | 8e-77 | 37.74% (469) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3734c | - | 1e-172 | 65.86% (454) | hypothetical protein Rv3734c |
| M. leprae Br4923 | MLBr_01244 | - | 1e-22 | 26.62% (402) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 1e-121 | 48.26% (460) | hypothetical protein MAB_4544c |
| M. avium 104 | MAV_0355 | - | 1e-176 | 67.56% (450) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 1e-165 | 63.38% (456) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 1e-157 | 62.39% (452) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1193 | - | 0.0 | 99.33% (450) | hypothetical protein MUL_1193 |
| M. vanbaalenii PYR-1 | Mvan_0444 | - | 8e-78 | 37.42% (465) | hypothetical protein Mvan_0444 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0529|M.marinum_M -MTSMELMMPTDAS----FLFTESREHPMHVAGLQLFDPP-DAAGPGFVD
MUL_1193|M.ulcerans_Agy99 ----MELMMPTDAS----FLFTESREHPMHVAGLQLFDPP-DAAGPGFVD
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
Mb3761c|M.bovis_AF2122/97 ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
Rv3734c|M.tuberculosis_H37Rv ----MDLMMPNDSM----FLFIESREHPMHVGGLSLFEPP-QGAGPEFVR
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
Mvan_0444|M.vanbaalenii_PYR-1 ----MDLLEPLDAA----MITAEALSEPLHTAAVLILCPP-ADAGPGYVD
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFR
: * : . ..: .
MMAR_0529|M.marinum_M EIYRCLAAN-REGQPAFRKHPATLLGGITNLGWQYDNEIDTDYHVRRSVL
MUL_1193|M.ulcerans_Agy99 EIYRCLAAN-REGQPAFRKHPATLLGGITNLGWQYDNEIDTDYHVRRSVL
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVRH-TDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSAL
TH_2030|M.thermoresistible__bu GLHQRLAAG-RELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSAL
Mb3761c|M.bovis_AF2122/97 EFTERLVAN-DEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSAL
Rv3734c|M.tuberculosis_H37Rv EFTERLVAN-DEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSAL
MAV_0355|M.avium_104 DFYKQLVAQ-PDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSAL
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMST-TEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSAL
Mflv_1058|M.gilvum_PYR-GCK GMIDEARRQ-EVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSAL
Mvan_0444|M.vanbaalenii_PYR-1 ELYRSALADTAELDPRFRRHPHAGLDTAGLWVWHTDEIIDMRKHLQRRTL
MLBr_01244|M.leprae_Br4923 SRIEDVSQR----VLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRV
*: * * .: *::* :
MMAR_0529|M.marinum_M PYPGRVSELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHA
MUL_1193|M.ulcerans_Agy99 PYPGRVRELLQLVSQLHSHLLDRHYPLWEMHVVDGLADGRFAIYSKFHHA
MSMEG_6322|M.smegmatis_MC2_155 PSPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHS
TH_2030|M.thermoresistible__bu PGPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHA
Mb3761c|M.bovis_AF2122/97 PSPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHA
Rv3734c|M.tuberculosis_H37Rv PSPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHA
MAV_0355|M.avium_104 PSPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHA
MAB_4544c|M.abscessus_ATCC_199 PRPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHA
Mflv_1058|M.gilvum_PYR-GCK ASPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHA
Mvan_0444|M.vanbaalenii_PYR-1 PAGADHEALWRLISELHSEPLERSRPMWMAYLIDGLADGRFVYYIKVHHT
MLBr_01244|M.leprae_Br4923 PDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHA
. : : . : :: * * :::*: ** . :. *:
MMAR_0529|M.marinum_M LLDGASALMLLQRALSDDPRDTEVRAPWNL--PPQPDHAVGS--------
MUL_1193|M.ulcerans_Agy99 LLDGASALMLLQRALSDDPRDTEVRAPWNL--PPQPDHAVGS--------
MSMEG_6322|M.smegmatis_MC2_155 LIDGVSAMKLVERTLSEDPSDTTVRVPWNL--PRR-ESSRRAGSS-----
TH_2030|M.thermoresistible__bu LIDGVAVMKLMQRTLSTDPGDD-ARVPWNL--PPP-RRNP-AGPV-----
Mb3761c|M.bovis_AF2122/97 LIDGVSAMKLAQRTLSADPDDAEVRAIWNL--PPRPRTRPPSDGS-----
Rv3734c|M.tuberculosis_H37Rv LIDGVSAMKLAQRTLSADPDDAEVRAIWNL--PPRPRTRPPSDGS-----
MAV_0355|M.avium_104 LIDGVSAQKLMQRALSSDPDDPEIRAPWTL--PKRSRKAGPS--------
MAB_4544c|M.abscessus_ATCC_199 VIDGVGALRMMMRSLSDDPDARDCQAVWAP--AKRRAKSSIVSTTN--TS
Mflv_1058|M.gilvum_PYR-GCK LVDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRSRRDPGAAESS--NP
Mvan_0444|M.vanbaalenii_PYR-1 VIDGVAGLAMIAGALTTDPDKRSMRPLYAHKSPAGNGSTSRRRIPNPLSL
MLBr_01244|M.leprae_Br4923 ITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGIN--HL
: ** . : :
MMAR_0529|M.marinum_M --SRLGSLANTAGSLMALGPSTVSLIRAALVEQQ--------LTLPFGAP
MUL_1193|M.ulcerans_Agy99 --SRLGSLANTAGSLMALGPSTVSLIRAALVEQQ--------LTLPFGAP
MSMEG_6322|M.smegmatis_MC2_155 --SLARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPFGAP
TH_2030|M.thermoresistible__bu --SRLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPFGAP
Mb3761c|M.bovis_AF2122/97 --SLLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAP
Rv3734c|M.tuberculosis_H37Rv --SLLDALFKMAGSVVGLAPSTLKLARAALLEQQ--------LTLPFAAP
MAV_0355|M.avium_104 --SRLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPFGAP
MAB_4544c|M.abscessus_ATCC_199 AIDLVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPLSAP
Mflv_1058|M.gilvum_PYR-GCK LTATLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSVSAP
Mvan_0444|M.vanbaalenii_PYR-1 ARVALRGLTGGIETARQLAIAEISTVANSLGSGT--------AALPLEAP
MLBr_01244|M.leprae_Br4923 PVALAGGVVGGLSGVASVAGRAILRPASTVSGVVG-YVRSGIRVLSQAAE
: : . . *
MMAR_0529|M.marinum_M RTLFNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQY
MUL_1193|M.ulcerans_Agy99 RTLFNVKVGGARRCAAQSWSLDRFRAVAKCAGVTINDVVLAMCAGALRQY
MSMEG_6322|M.smegmatis_MC2_155 RTMFNVKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRAY
TH_2030|M.thermoresistible__bu RTMFNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQY
Mb3761c|M.bovis_AF2122/97 HSMFNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYY
Rv3734c|M.tuberculosis_H37Rv HSMFNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYY
MAV_0355|M.avium_104 RTMLNVKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRYY
MAB_4544c|M.abscessus_ATCC_199 HTMLNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTY
Mflv_1058|M.gilvum_PYR-GCK HSILNARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGGLRKF
Mvan_0444|M.vanbaalenii_PYR-1 YTRFNGRIGRERSFAGGSWPKSRIRAVQKATGVTGNDVLTTVVAGVLREW
MLBr_01244|M.leprae_Br4923 PSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRY
: : . :: . : ** : * ** :
MMAR_0529|M.marinum_M LLEQNALPDAPLVALVPVSLRS---QTD-DSGGTMVGTVLCG-LATDTTD
MUL_1193|M.ulcerans_Agy99 LLEQNALPDAPLVALVPVSLRS---QTD-DSGDTMVGTVLCG-LATDTTD
MSMEG_6322|M.smegmatis_MC2_155 LAEQDALPDRPLIAMVPVSMRS---EHEADAGGNMVGSILCS-LGTDVED
TH_2030|M.thermoresistible__bu LLEHDALPATPLVAMVPVSLRS---ADESAGGGNRTGLVLCN-LATDSDD
Mb3761c|M.bovis_AF2122/97 LIERNALPDRPLIAMVPVSLRS---KEDADAGGNLVGSVLCN-LATHVDD
Rv3734c|M.tuberculosis_H37Rv LIERNALPDRPLIAMVPVSLRS---KEDADAGGNLVGSVLCN-LATHVDD
MAV_0355|M.avium_104 LLEQNALPDTPLIAMVPVSLRT---EEEADAGGNLVGAILCN-LATDSDD
MAB_4544c|M.abscessus_ATCC_199 LEEQNALPDKPLVAMCPVSIRA---EGDQNAGNSIT-ALLAN-LATDKPD
Mflv_1058|M.gilvum_PYR-GCK LSDFDKLPDRSLIAFLPVNVRP---KGD-EGGGNAVGAILAP-MGTDIED
Mvan_0444|M.vanbaalenii_PYR-1 LLARDELPNSSLVAICPVTVRGREHSAEDDEHGNLFGLQLCP-LGTDLAD
MLBr_01244|M.leprae_Br4923 H-EALGVSISTLPMAVPVNVRT---EADVVGSNRFVGVTLAAPLGTN--D
:. .* **.:* : . *. :.*. *
MMAR_0529|M.marinum_M PAKRLEMISQSMRRNKKAFSELSPLQAKALWAFNMAPL--TLT-AVPGFV
MUL_1193|M.ulcerans_Agy99 PAKRLEMISQSMRRNKKAFSELSPLQAKALWAFNMAPL--TLT-AVPGFV
MSMEG_6322|M.smegmatis_MC2_155 PADRLAVIRRSITDNKRVFSELPRLQALALSALLIAPL--GLTTAFPGFV
TH_2030|M.thermoresistible__bu PAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAPL--GLG-AVPGVV
Mb3761c|M.bovis_AF2122/97 PAQRIQTISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFL
Rv3734c|M.tuberculosis_H37Rv PAQRIQTISASMDGNKKVLSELPQLQVLALSALNMAPL--TLA-GVPGFL
MAV_0355|M.avium_104 PAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSSL--ALA-AVPGWV
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPV--LTG-AVPGLV
Mflv_1058|M.gilvum_PYR-GCK PVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQ
Mvan_0444|M.vanbaalenii_PYR-1 PLERLDYIHRAMTWAKHQVTDRGSNATMLLLAPSIAVT--VLS-PIAPLA
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRR----DEPAMNIIGSLAPLMTVLP----ASVLDFI
* *: * : . * : .
MMAR_0529|M.marinum_M PWTKPSFNVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSN
MUL_1193|M.ulcerans_Agy99 PWTKPSFNVIVSNLPGPTKPMYWHGARLDSIYPLSIAHDGQALSITLLSN
MSMEG_6322|M.smegmatis_MC2_155 DATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLSIALDGQALNMTVVSN
TH_2030|M.thermoresistible__bu SSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLSIVLDGQALNITLVTN
Mb3761c|M.bovis_AF2122/97 SAVPPPFNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNN
Rv3734c|M.tuberculosis_H37Rv SAVPPPFNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNN
MAV_0355|M.avium_104 SATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLSIVLDGQALNITLASN
MAB_4544c|M.abscessus_ATCC_199 DRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSS
Mflv_1058|M.gilvum_PYR-GCK PPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVSIPIHGMALNITLQSY
Mvan_0444|M.vanbaalenii_PYR-1 PRLRRGYNVSISSVPGPQAEMYWNGAHLEEIYPVSTAIDGQALNVTMCSY
MLBr_01244|M.leprae_Br4923 VDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPR-PGVAMMAVLMSR
:: *.:*. :: .: * . * *: . .
MMAR_0529|M.marinum_M AGTLEFGLVGCRRSVPHLQRLLLHLETSLHGLEQAVGL------------
MUL_1193|M.ulcerans_Agy99 AGTLEFGLVGCRRSVPHLQRLLLHLETSLYGLEQAVGL------------
MSMEG_6322|M.smegmatis_MC2_155 AHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA------------
TH_2030|M.thermoresistible__bu ADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG------------
Mb3761c|M.bovis_AF2122/97 AGNLDFGLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI------------
Rv3734c|M.tuberculosis_H37Rv AGNLDFGLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI------------
MAV_0355|M.avium_104 AGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE------------
MAB_4544c|M.abscessus_ATCC_199 GSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA-------------
Mflv_1058|M.gilvum_PYR-GCK ADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI------------
Mvan_0444|M.vanbaalenii_PYR-1 ADRVTFGYVSGRDVVPDIGSLIPLTERVLADLEAAVAAQS----------
MLBr_01244|M.leprae_Br4923 GGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAA
. . * : : : :
MMAR_0529|M.marinum_M -------------
MUL_1193|M.ulcerans_Agy99 -------------
MSMEG_6322|M.smegmatis_MC2_155 -------------
TH_2030|M.thermoresistible__bu -------------
Mb3761c|M.bovis_AF2122/97 -------------
Rv3734c|M.tuberculosis_H37Rv -------------
MAV_0355|M.avium_104 -------------
MAB_4544c|M.abscessus_ATCC_199 -------------
Mflv_1058|M.gilvum_PYR-GCK -------------
Mvan_0444|M.vanbaalenii_PYR-1 -------------
MLBr_01244|M.leprae_Br4923 RSSGSPAGWLSSS