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MDLLEPLDAAMITAEALSEPLHTAAVLILCPPADAGPGYVDELYRSALADTAELDPRFRRHPHAGLDTAG LWVWHTDEIIDMRKHLQRRTLPAGADHEALWRLISELHSEPLERSRPMWMAYLIDGLADGRFVYYIKVHH TVIDGVAGLAMIAGALTTDPDKRSMRPLYAHKSPAGNGSTSRRRIPNPLSLARVALRGLTGGIETARQLA IAEISTVANSLGSGTAALPLEAPYTRFNGRIGRERSFAGGSWPKSRIRAVQKATGVTGNDVLTTVVAGVL REWLLARDELPNSSLVAICPVTVRGREHSAEDDEHGNLFGLQLCPLGTDLADPLERLDYIHRAMTWAKHQ VTDRGSNATMLLLAPSIAVTVLSPIAPLAPRLRRGYNVSISSVPGPQAEMYWNGAHLEEIYPVSTAIDGQ ALNVTMCSYADRVTFGYVSGRDVVPDIGSLIPLTERVLADLEAAVAAQS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0444 | - | - | 100% (469) | hypothetical protein Mvan_0444 |
| M. vanbaalenii PYR-1 | Mvan_5773 | - | 3e-66 | 33.91% (463) | hypothetical protein Mvan_5773 |
| M. vanbaalenii PYR-1 | Mvan_3601 | - | 1e-46 | 30.80% (461) | hypothetical protein Mvan_3601 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3766c | - | 3e-77 | 37.82% (468) | hypothetical protein Mb3766c |
| M. gilvum PYR-GCK | Mflv_1058 | - | 6e-70 | 36.13% (476) | hypothetical protein Mflv_1058 |
| M. tuberculosis H37Rv | Rv3740c | - | 3e-78 | 38.03% (468) | hypothetical protein Rv3740c |
| M. leprae Br4923 | MLBr_01244 | - | 3e-16 | 25.19% (385) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 2e-71 | 33.62% (467) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_2073 | - | 1e-152 | 57.23% (470) | hypothetical protein MMAR_2073 |
| M. avium 104 | MAV_0355 | - | 3e-72 | 35.19% (466) | bifunctional wax ester synthase/acyl-coadiacylglycerol |
| M. smegmatis MC2 155 | MSMEG_6322 | - | 5e-79 | 38.03% (468) | bifunctional wax ester synthase/acyl-CoA diacylglycerol |
| M. thermoresistible (build 8) | TH_2030 | - | 4e-75 | 38.20% (466) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3271 | - | 1e-149 | 56.08% (469) | hypothetical protein MUL_3271 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2073|M.marinum_M ----MHPLDPLDAL----MLTAELVSNPMHVGALLILSPP-PGSGADYVD
MUL_3271|M.ulcerans_Agy99 ----MHPLDPLDAL----MLTAELVSNPMHVGALLILSPP-PGSGADYVD
Mvan_0444|M.vanbaalenii_PYR-1 ----MDLLEPLDAA----MITAEALSEPLHTAAVLILCPP-ADAGPGYVD
MSMEG_6322|M.smegmatis_MC2_155 -MNRMQLMSPTDSM----FLIAESREHPMHVGGLALYDPP-DDAGPEFVR
TH_2030|M.thermoresistible__bu ----MRLISPADSM----FLLAESREHPMHVAGLQLFEPPPGTAGPEFLQ
MAV_0355|M.avium_104 ----MELIMPTDAV----FLLGESREHPMHVGGLQLYQPP-EGAGRNFVR
Mb3766c|M.bovis_AF2122/97 -------MSPIDAL----FLSAESREHPLHVGALQLFEPP-AGAGRGFVR
Rv3740c|M.tuberculosis_H37Rv -------MSPIDAL----FLSAESREHPLHVGALQLFEPP-AGAGRGFVR
MAB_4544c|M.abscessus_ATCC_199 ----MPFMPVSDSM----FLIGETREHPFHVGGLQLFKPP-VDAGPDYAE
Mflv_1058|M.gilvum_PYR-GCK MSANSVRLGLQDLM----FIYGETSSSKMHVGGLLPFTPP-ADAPRDYLR
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELL--DTTPDWNR
: * : . ..: : :
MMAR_2073|M.marinum_M QLHRETLAGGEPIDPRLRRYPHRGVDTGGVWVWRDAQAVDIGYHCQRRSV
MUL_3271|M.ulcerans_Agy99 QLHSETLAGGEPIDPRLRRYPHRGVDTGGVWVWRDAQAVDIGYHCQRRSV
Mvan_0444|M.vanbaalenii_PYR-1 ELYRSALADTAELDPRFRRHPHAGLDTAGLWVWHTDEIIDMRKHLQRRTL
MSMEG_6322|M.smegmatis_MC2_155 ELYEEMVR-HTDFQPVFRKHPATLLGGIANVGWTLDDEVDLDYHLRRSAL
TH_2030|M.thermoresistible__bu GLHQRLAA-GRELHPTFRKHPATLFGGIAHLGWAVDDDVDFDYHLRRSAL
MAV_0355|M.avium_104 DFYKQLVA-QPDFQPTFRKHPAKFVGGIANLGWSYDADVDVDYHVRRSAL
Mb3766c|M.bovis_AF2122/97 ETYQAMLQ-CREIAPLFRKRPTSLHGALINLGWSTDADVDLGYHARRSAL
Rv3740c|M.tuberculosis_H37Rv ETYQAMLQ-CREIAPLFRKRPTSLHGALINLGWSTDADVDLGYHARRSAL
MAB_4544c|M.abscessus_ATCC_199 VFYEQLMS-TTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSAL
Mflv_1058|M.gilvum_PYR-GCK GMIDEARR-QEVVAPWNRRLAYPRLQFSPLHSWVTDEDFDFDYHVRRSAL
MLBr_01244|M.leprae_Br4923 --FRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRV
*: * .: * :* :
MMAR_2073|M.marinum_M DAGRD--AFWRLIAELDAQRLELSRPMWMSYLIDGLEDGRFAFYIKVHHT
MUL_3271|M.ulcerans_Agy99 DAGRD--AFWRLIAELDAQRLELSRPMCMSYLIDGLEDGRFAFYIKVHHT
Mvan_0444|M.vanbaalenii_PYR-1 PAGADHEALWRLISELHSEPLERSRPMWMAYLIDGLADGRFVYYIKVHHT
MSMEG_6322|M.smegmatis_MC2_155 PSPGRPRELLELTSRVHGTLLDRHRPLWEAYLIEGMADGRFAVYTKVHHS
TH_2030|M.thermoresistible__bu PGPGRIRELLDLTSRWHGTLLDRHRPLWEVHLVEGLADGRVAIYFKVHHA
MAV_0355|M.avium_104 PSPRRVRELLELTSRWHSSLLDRHRPLWETHIVEGLKDGRFAIYTKVHHA
Mb3766c|M.bovis_AF2122/97 PAPGRVRELLELTSRLHSNLLDRHRPLWETHVIEGLRDGRFAIYSKMHHA
Rv3740c|M.tuberculosis_H37Rv PAPGRVRELLELTSRLHSNLLDRHRPLWETHVIEGLRDGRFAIYSKMHHA
MAB_4544c|M.abscessus_ATCC_199 PRPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHHA
Mflv_1058|M.gilvum_PYR-GCK ASPGDERELGVLVSRLHSNHLDLTRPPWELHVIEGLEGGRFALYMKIHHA
MLBr_01244|M.leprae_Br4923 PDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHA
. : . :: ** :::*: ** . :: *:
MMAR_2073|M.marinum_M VVDGVAGFQMIAEALSTDPECRSMPPFYADRHLDHPPSSTSTGLLARLFA
MUL_3271|M.ulcerans_Agy99 VVDGVAGFQMIAEALSTDPECRSMPPFYADRHLDHPPSSTSTGLLARLFA
Mvan_0444|M.vanbaalenii_PYR-1 VIDGVAGLAMIAGALTTDPDKRSMRPLYAHKSPAGN-GSTSRRRIPNPLS
MSMEG_6322|M.smegmatis_MC2_155 LIDGVSAMKLVERTLSEDPSDTTVRVPWNLPRR------ESSRRAGSSS-
TH_2030|M.thermoresistible__bu LIDGVAVMKLMQRTLSTDPGDD-ARVPWNLPPP------RRNP-AGPVS-
MAV_0355|M.avium_104 LIDGVSAQKLMQRALSSDPDDPEIRAPWTLP--------KRSRKAGPSS-
Mb3766c|M.bovis_AF2122/97 LVDGVSGLTLMRQPMTTDPIEGKLRTAWSPAT-------QHTAIKRRRG-
Rv3740c|M.tuberculosis_H37Rv LVDGVSGLTLMRQPMTTDPIEGKLRTAWSPAT-------QHTAIKRRRG-
MAB_4544c|M.abscessus_ATCC_199 VIDGVGALRMMMRSLSDDPDARDCQAVWAPAKRRAKSSIVSTTNTSAID-
Mflv_1058|M.gilvum_PYR-GCK LVDGYSAMRMLGRSLSTDPASRDTRMFFNVPSPTRS---RRDPGAAESSN
MLBr_01244|M.leprae_Br4923 ITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLS---RNDLMLQGINH
: ** . :. :
MMAR_2073|M.marinum_M PLRSLAGAAASGIGLINHVVAGEASTVWDSLIGHT--------TVLPFTA
MUL_3271|M.ulcerans_Agy99 PLRSLAGAVASGIGLINHVVAGEASTVWDSLIGHT--------TVLPFTA
Mvan_0444|M.vanbaalenii_PYR-1 LARVALRGLTGGIETARQLAIAEISTVANSLGSGT--------AALPLEA
MSMEG_6322|M.smegmatis_MC2_155 ----LARTATGAATSLAALAPSTIRLARAALLEQQ--------LTLPFGA
TH_2030|M.thermoresistible__bu ----RLRSATGAVGSVAALAPSTLSLARAALLEQR--------LTLPFGA
MAV_0355|M.avium_104 ----RLSSLVHAAGSVAALAPSTVSLARAALVEQQ--------LTLPFGA
Mb3766c|M.bovis_AF2122/97 ----RLQQLGGMLGSVAGLAPSTLRLARSALIEQQ--------LTLPFGA
Rv3740c|M.tuberculosis_H37Rv ----RLQQLGGMLGSVAGLAPSTLRLARSALIEQQ--------LTLPFGA
MAB_4544c|M.abscessus_ATCC_199 ----LVKGAAGAVRQVVSIPPGLLKYGRHALSDPQ--------LVKPLSA
Mflv_1058|M.gilvum_PYR-GCK PLTATLRALGGVSSAVTGGVSSAVDLTNALVNTQIRRDGENAHIAGSVSA
MLBr_01244|M.leprae_Br4923 LPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVG-YVRSGIRVLSQAA
: . . *
MMAR_2073|M.marinum_M PYTRFNGRLGAQRAVAAGSWSRHRIEAIQRAADVTANDVVTAVIAGALRR
MUL_3271|M.ulcerans_Agy99 PYTRFNGRLGAQRAVAAGSWSRHRIEAIQRAADVTANDVVTAVIAGALRR
Mvan_0444|M.vanbaalenii_PYR-1 PYTRFNGRIGRERSFAGGSWPKSRIRAVQKATGVTGNDVLTTVVAGVLRE
MSMEG_6322|M.smegmatis_MC2_155 PRTMFNVKIGGARRVAAQSWPLERLRRIKAVTGATINDIVLAMCAGALRA
TH_2030|M.thermoresistible__bu PRTMFNVRIGGARRVAAQSWPLQRIRRIRQAAGXTLNDVALAMCAGALRQ
MAV_0355|M.avium_104 PRTMLNVKIGGARRCAAQSWPLERIKNVKNAAGVTVNDVVLAMCSGALRY
Mb3766c|M.bovis_AF2122/97 PHTMLNVAVGGARRCAAQSWPLDRVKAVKDAAGVSLNDVVLAMCAGALRE
Rv3740c|M.tuberculosis_H37Rv PHTMLNVAVGGARRCAAQSWPLDRVKAVKDAAGVSLNDVVLAMCAGALRE
MAB_4544c|M.abscessus_ATCC_199 PHTMLNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRT
Mflv_1058|M.gilvum_PYR-GCK PHSILNARISRNRRFATQQYEFDRLKKLSSQHGATLNDVALAIIGGGLRK
MLBr_01244|M.leprae_Br4923 EPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRR
: : . :. . : ** : * **
MMAR_2073|M.marinum_M WLLAHSELPDHSLVAICPITVRDREHPSAPDEHANMFGLWLCPLGTDLPD
MUL_3271|M.ulcerans_Agy99 WLLAHSELADHSLVAICPITVRDREHPSAPDEHANMFGLWLCPLGTDLPD
Mvan_0444|M.vanbaalenii_PYR-1 WLLARDELPNSSLVAICPVTVRGREHSAEDDEHGNLFGLQLCPLGTDLAD
MSMEG_6322|M.smegmatis_MC2_155 YLAEQDALPDRPLIAMVPVSMRSEHEAD---AGGNMVGSILCSLGTDVED
TH_2030|M.thermoresistible__bu YLLEHDALPATPLVAMVPVSLRSADESA---GGGNRTGLVLCNLATDSDD
MAV_0355|M.avium_104 YLLEQNALPDTPLIAMVPVSLRTEEEAD---AGGNLVGAILCNLATDSDD
Mb3766c|M.bovis_AF2122/97 YLDDNDALPDTPLVAMVPVSLRTDRDS----VGGNMVGAVLCNLATHLDD
Rv3740c|M.tuberculosis_H37Rv YLDDNDALPDTPLVAMVPVSLRTDRDS----VGGNMVGAVLCNLATHLDD
MAB_4544c|M.abscessus_ATCC_199 YLEEQNALPDKPLVAMCPVSIRAEGDQ----NAGNSITALLANLATDKPD
Mflv_1058|M.gilvum_PYR-GCK FLSDFDKLPDRSLIAFLPVNVRPKGDE----GGGNAVGAILAPMGTDIED
MLBr_01244|M.leprae_Br4923 YHEALG-VSISTLPMAVPVNVRTEADVV----GSNRFVGVTLAAPLGTND
: . :. .* *:.:* . .* *
MMAR_2073|M.marinum_M PHRRLDLIHRSMSEGKHWVSARGSAASLLTTAASIAATVVFP---LLPFT
MUL_3271|M.ulcerans_Agy99 PHRRLDLIHRSMSEGKHWVSARGSAASLLTTAASIAVTVVFP---LLPST
Mvan_0444|M.vanbaalenii_PYR-1 PLERLDYIHRAMTWAKHQVTDRGSNATMLLLAPSIAVTVLSP---IAPLA
MSMEG_6322|M.smegmatis_MC2_155 PADRLAVIRRSITDNKRVFSELPRLQALALSALLIAPLGLTT--AFPGFV
TH_2030|M.thermoresistible__bu PAERLDRISSSMRSNKRVFSQLPRVQAMALSAAMIAPLGLG---AVPGVV
MAV_0355|M.avium_104 PAQRLLTISESMRSNKKVFSQLPRFQALALSAANLSSLALA---AVPGWV
Mb3766c|M.bovis_AF2122/97 PADRLNAIHASMRGNKNVLSQLPRAQALAVSLLLLSPAALN---TLPGLA
Rv3740c|M.tuberculosis_H37Rv PADRLNAIHASMRGNKNVLSQLPRAQALAVSLLLLSPAALN---TLPGLA
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTG---AVPGLV
Mflv_1058|M.gilvum_PYR-GCK PVERLDTITTATRAAKGQLQSMSPAAIIAYSAALLAPAGSQIAGALTGVQ
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRR----DEPAMNIIGSLAPLMTVLPAS----VLDFI
* *: * : : : .
MMAR_2073|M.marinum_M PKIRTGYNLPISHVGGPRAERYWNGAHVDEMYPVS----------TVYDG
MUL_3271|M.ulcerans_Agy99 PKIRTGYNLPISHVGGPRVERYWNGAHVDEMYPVS----------TVYDG
Mvan_0444|M.vanbaalenii_PYR-1 PRLRRGYNVSISSVPGPQAEMYWNGAHLEEIYPVS----------TAIDG
MSMEG_6322|M.smegmatis_MC2_155 DATAPPFNLVISNVPGPKKPLYWRGARLAGNYPLS----------IALDG
TH_2030|M.thermoresistible__bu SSAPPPFNLVISNVPGAPEPRYWMGARLAGNYPLS----------IVLDG
MAV_0355|M.avium_104 SATSPPFNIVISNVPGPTAPLYYGGARLDGNYPLS----------IVLDG
Mb3766c|M.bovis_AF2122/97 KATPPPFNVCISNVPGAREPLYFNGARMVGNYPMS----------LVLDG
Rv3740c|M.tuberculosis_H37Rv KATPPPFNVCISNVPGAREPLYFNGARMVGNYPMS----------LVLDG
MAB_4544c|M.abscessus_ATCC_199 DRTAPAFNVIISNVPGPRTDMFWNGFEMDGCYPAS----------IPIDG
Mflv_1058|M.gilvum_PYR-GCK PPWPYTFNLCVSNVPGPREPLYFNGSRLEATYPVS----------IPIHG
MLBr_01244|M.leprae_Br4923 VDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGVAMMAVLMSRG
:: * : . :: * .: * . *
MMAR_2073|M.marinum_M QALNVTTCSYADRIGFGYVAGREVMPDIDTLIPLTEECLTELESCVGVPP
MUL_3271|M.ulcerans_Agy99 QALNVTTCSYADRIGFGYVAGREVMPDIDTLIPLTEECLTELESCVGVPP
Mvan_0444|M.vanbaalenii_PYR-1 QALNVTMCSYADRVTFGYVSGRDVVPDIGSLIPLTERVLADLEAAVAAQS
MSMEG_6322|M.smegmatis_MC2_155 QALNMTVVSNAHNLDFGLVGCRRSVPHLQRLLGHLETSLKDLETATGA--
TH_2030|M.thermoresistible__bu QALNITLVTNADNLDFGLVGARGSVPHLQRLLGHLEDSLQQLERAVGG--
MAV_0355|M.avium_104 QALNITLASNAGNLDFGLVGCRRSVPHLQRLLMHLESSLKDLERAVGE--
Mb3766c|M.bovis_AF2122/97 QALNITLTSTADSLDFGVVGCCRSVPHVQRVLSHLETSLKELERAVGL--
Rv3740c|M.tuberculosis_H37Rv QALNITLTSTADSLDFGVVGCRRSVPHVQRVLSHLETSLKELERAVGL--
MAB_4544c|M.abscessus_ATCC_199 VALNITCTSSGSSMHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA---
Mflv_1058|M.gilvum_PYR-GCK MALNITLQSYADTMNLGFVGCRDRLPHLQRLAVYTGDALAELEAASQI--
MLBr_01244|M.leprae_Br4923 GFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAAR
.:* : : . : . .
MMAR_2073|M.marinum_M RLSGHIG-----
MUL_3271|M.ulcerans_Agy99 RLSGHIG-----
Mvan_0444|M.vanbaalenii_PYR-1 ------------
MSMEG_6322|M.smegmatis_MC2_155 ------------
TH_2030|M.thermoresistible__bu ------------
MAV_0355|M.avium_104 ------------
Mb3766c|M.bovis_AF2122/97 ------------
Rv3740c|M.tuberculosis_H37Rv ------------
MAB_4544c|M.abscessus_ATCC_199 ------------
Mflv_1058|M.gilvum_PYR-GCK ------------
MLBr_01244|M.leprae_Br4923 SSGSPAGWLSSS