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M. marinum M MMAR_0264 (ctpA)

annotation: cation transporter p-type ATPase a CtpA
coordinates: 299893 - 302184
length: 763

STTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVRASVNFGTRTATVEAGEDVDAAAL
CEVIQQAGYQAEVQPDDGQGAGDPDAEHARHLLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLTA
LALPVVTWAAWPFHRVALRNARHHGASMETLISVGITAATIWSLYTVFGSHQLADRKGIWQALLGSDAIY
FEVAAGVTVFVLAGRYFEARAKSKAGSALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPGQT
IAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVEAAAVGADTRFAGMVRLVEQAQA
QKADAQRLADRIASVFVPCVFVIAALTAAGWLLAGGSPDRAFSAAIAVLVIACPCALGLATPTAMMVASG
RGAQLGIFLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGWDADEVLAIAATVEAASEHSVAL
AIAAATTQHDTVTEFRAIPGRGVSGTVSGRSVRVGKPSWIGSSSSDAALRAARRNAESLGETAVFVEIDG
APCGVIAVADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGIDEVIANILPEGKVDVIEQLR
DRGHVVAMVGDGINDGPALASADLGMAMGRGTDVAIGAADIILVRDNLDVVPLALGLAAATMRTVKLNLA
WAFGYNIAAIPIAAAGVLNPVVAGAAMAFSSFFVVSNSLQLRNFGAATSQTTTSTTEPGATE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0264ctpA-100% (763)cation transporter p-type ATPase a CtpA
M. marinum MMMAR_0269ctpB0.068.56% (741) cation-transporter p-type ATPase B CtpB
M. marinum MMMAR_0231ctpA_10.047.63% (758) cation transporter p-type ATPase CtpA_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0095ctpA0.084.54% (744) cation transporter P-type ATPase A
M. gilvum PYR-GCKMflv_2849-0.050.93% (752) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0092ctpA0.084.68% (744) cation transporter P-type ATPase A
M. leprae Br4923MLBr_01987ctpA0.076.78% (715) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-17548.12% (744) putative metal transporter ATPase
M. avium 104MAV_5246-0.050.40% (748) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.052.77% (739) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.052.49% (743) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4850ctpA0.099.08% (763) cation transporter p-type ATPase a CtpA
M. vanbaalenii PYR-1Mvan_3670-0.051.10% (771) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2849|M.gilvum_PYR-GCK          MTTS-----------IPVSGPSIELRIGGMTCASCANRIERKLNKIDGVA
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
MMAR_0264|M.marinum_M               --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
MUL_4850|M.ulcerans_Agy99           --MSTTIVTTDKHLERDQQVQRFQLGITGMSCFACARKVQSTLNKVPGVR
Mb0095|M.bovis_AF2122/97            ---MTAAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
Rv0092|M.tuberculosis_H37Rv         ---MTTAVTGEHHAS----VQRIQLRISGMSCSACAHRVESTLNKLPGVR
MLBr_01987|M.leprae_Br4923          --------------------------------MRAPNGWNNLPNKLSDFS
                                                                      ..   :   *:: .. 

Mflv_2849|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVQNAGYSAALPTPEKPALTGETGE
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPP--------
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
MMAR_0264|M.marinum_M               ASVNFGTRTATVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDPDAE
MUL_4850|M.ulcerans_Agy99           ASVNFGTRTAIVEAGEDVDAAALCEVIQQAGYQAEVQPDDGQGAGDSDAE
Mb0095|M.bovis_AF2122/97            AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
Rv0092|M.tuberculosis_H37Rv         AAVNFGTRVATIDTSEAVDAAALCQAVRRAGYQADLCTDDGRSASDPDAD
MLBr_01987|M.leprae_Br4923          TLVNSATRVAAINLSEVTQTAEVCEAVRRAALCTDG--GEALQRRQADAD
                                    : ** . . * :          :   :. ..  :                

Mflv_2849|M.gilvum_PYR-GCK          TEDP--------DLVSLRHRLTGSVLLSVPVIAMAMIPVLQFTYWQWASL
MAV_5246|M.avium_104                RDDP--------ELASLRRRLVTAIALAGPVIAVAMIPALQFQHWHWAAL
MSMEG_5014|M.smegmatis_MC2_155      PEDR--------ATDALRTRLLVSAVLTVPVIAMAMVPALQFTNWQWLSL
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLSMIPALQFTHWQWLAL
Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVPVIAMSMIPALQFTNWQWLAL
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVISMAMPLHFSGWEILVA
MMAR_0264|M.marinum_M               HARH--------LLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT
MUL_4850|M.ulcerans_Agy99           HARH--------LLIRLAVAAVLFVPLADLSVMFAVVPSTRFTGWEWVLT
Mb0095|M.bovis_AF2122/97            HARQ--------LLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
Rv0092|M.tuberculosis_H37Rv         HARQ--------LLIRLAIAAVLFVPVADLSVMFGVVPATRFTGWQWVLS
MLBr_01987|M.leprae_Br4923          NARY--------LLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWEWMLT
                                                              ::   : ..:    :*  *.    

Mflv_2849|M.gilvum_PYR-GCK          VLAAPVIVWAAWPFHRAAWANLRHATATMDTLISLGTLSAFLWSLYALFF
MAV_5246|M.avium_104                ALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYALVL
MSMEG_5014|M.smegmatis_MC2_155      TLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYALFW
TH_4361|M.thermoresistible__bu      TLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLWALFF
Mvan_3670|M.vanbaalenii_PYR-1       TLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLWALFI
MAB_3984c|M.abscessus_ATCC_199      ALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLWVLFA
MMAR_0264|M.marinum_M               ALALPVVTWAAWPFHRVALRNARHHGASMETLISVGITAATIWSLYTVFG
MUL_4850|M.ulcerans_Agy99           ALALPVVTWAAWPFHRIALRNARHHGASMETLISVGITAATIWSLYTVFG
Mb0095|M.bovis_AF2122/97            ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
Rv0092|M.tuberculosis_H37Rv         ALALPVVTWAAWPFHRVAMRNARHHAASMETLISVGITAATIWSLYTVFG
MLBr_01987|M.leprae_Br4923          ALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLYTVFG
                                    .*: *:: * . ***  *  * ::  ::*:**:* *  :*  ***:.:. 

Mflv_2849|M.gilvum_PYR-GCK          GTAGTPGMKHPFELTLAP----SHGAA--NIYLEVAAGVTTFILAGRYFE
MAV_5246|M.avium_104                GAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFE
MSMEG_5014|M.smegmatis_MC2_155      GTAGVPGMTHPFSLVGSR----TDGAG--NIYLEVAAGVTTFILAGRYFE
TH_4361|M.thermoresistible__bu      TAAGMPGMTMTFTLLP-AD------TGEPHIYLEVAAAVTTFIIAGRYFE
Mvan_3670|M.vanbaalenii_PYR-1       GHAGMPGMRMAFSLLPDAG------SETEHIYLEVAAAVTVFILAGRYFE
MAB_3984c|M.abscessus_ATCC_199      NAGHTHGDVH--------------------VYFEVVAAVTVFLLAGRFAE
MMAR_0264|M.marinum_M               SHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAGRYFE
MUL_4850|M.ulcerans_Agy99           SHQLADRKGIWQALLGSD-----------AIYFEVAAGVTVFVLAGRYFE
Mb0095|M.bovis_AF2122/97            NHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVGRYFE
Rv0092|M.tuberculosis_H37Rv         NHSPIERSGIWQALLGSD-----------AIYFEVAAGVTVFVLVGRYFE
MLBr_01987|M.leprae_Br4923          HHQSTEHRGVWRALLGSD-----------AIYFEVAAGITVFVLAGKYYT
                                                                  :*:**.*.:* *::.*::  

Mflv_2849|M.gilvum_PYR-GCK          KRSKRQAGAALRALLEMGAKEVSVLR-DGVESKIAVEDLVVGDEFVVRPG
MAV_5246|M.avium_104                RRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFVVRPG
MSMEG_5014|M.smegmatis_MC2_155      AKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFVVRPG
TH_4361|M.thermoresistible__bu      ARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFVVRPG
Mvan_3670|M.vanbaalenii_PYR-1       ARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFVVRPG
MAB_3984c|M.abscessus_ATCC_199      SRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFVVRPG
MMAR_0264|M.marinum_M               ARAKSKAGSALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPG
MUL_4850|M.ulcerans_Agy99           ARAKSKAGAALRALAALSAKEVAVLQPDGSELVVPADELQEQDRFVVRPG
Mb0095|M.bovis_AF2122/97            ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
Rv0092|M.tuberculosis_H37Rv         ARAKSQAGSALRALAALSAKEVAVLLPDGSEMVIPADELKEQQRFVVRPG
MLBr_01987|M.leprae_Br4923          ARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFVVRPG
                                     ::*  :. ** **  :.*::.:::   * *  :.   *   : ******

Mflv_2849|M.gilvum_PYR-GCK          EKIATDGVVASGTSAVDASMLTGESVPVEVGPGDTVVGATVNAGGRLVVR
MAV_5246|M.avium_104                ERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVR
MSMEG_5014|M.smegmatis_MC2_155      EKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRLVVR
TH_4361|M.thermoresistible__bu      EKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHLQVR
Mvan_3670|M.vanbaalenii_PYR-1       EKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGRLLVR
MAB_3984c|M.abscessus_ATCC_199      ERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGRIVVR
MMAR_0264|M.marinum_M               QTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVE
MUL_4850|M.ulcerans_Agy99           QTIAADGLVLDGSAAVDMSTMTGEAKPTRVRPGGQVIGGTVVLDGRLIVE
Mb0095|M.bovis_AF2122/97            QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
Rv0092|M.tuberculosis_H37Rv         QIVAADGLAVDGSAAVDMSAMTGEAKPTRVRPGGQVIGGTTVLDGRLIVE
MLBr_01987|M.leprae_Br4923          QTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGRLIVE
                                    : :*:** .  * :::. : :***: * .*  *  * *. .   *:: *.

Mflv_2849|M.gilvum_PYR-GCK          AARVGSDTQLAQMAQLVENAQTGKAQVQRLADRISGVFVPIVLAIAVITL
MAV_5246|M.avium_104                ATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATL
MSMEG_5014|M.smegmatis_MC2_155      ANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAVATL
TH_4361|M.thermoresistible__bu      ATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSALTL
Mvan_3670|M.vanbaalenii_PYR-1       ATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALSVATL
MAB_3984c|M.abscessus_ATCC_199      ANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAISALTF
MMAR_0264|M.marinum_M               AAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIAALTA
MUL_4850|M.ulcerans_Agy99           AAAVGADTRFAGMVRLVEQAQAQKADAQRLADRIASVFVPCVFVIAALTA
Mb0095|M.bovis_AF2122/97            AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
Rv0092|M.tuberculosis_H37Rv         AAAVGADTQFAGMVRLVEQAQAQKADAQRLADRISSVFVPAVLVIAALTA
MLBr_01987|M.leprae_Br4923          AAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVAALTA
                                    *  :* :*::* *.:**  **  :*..******::.**** *: ::. * 

Mflv_2849|M.gilvum_PYR-GCK          GAWLGAGFP-VAAAFTAAVAVLVIACPCALGLATPTALLVGTGRGAQMGV
MAV_5246|M.avium_104                AGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLGV
MSMEG_5014|M.smegmatis_MC2_155      GFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
TH_4361|M.thermoresistible__bu      AGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQLGI
Mvan_3670|M.vanbaalenii_PYR-1       AAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQLGI
MAB_3984c|M.abscessus_ATCC_199      VAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGAQLGV
MMAR_0264|M.marinum_M               AGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI
MUL_4850|M.ulcerans_Agy99           AGWLLAGGS-PDRAFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI
Mb0095|M.bovis_AF2122/97            AGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
Rv0092|M.tuberculosis_H37Rv         AGWLIAGGQ-PDRAVSAALAVLVIACPCALGLATPTAMMVASGRGAQLGI
MLBr_01987|M.leprae_Br4923          VGWLIAGSG-PDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGAQLGI
                                      *          ..:**:***:**************::*.:**.**:*:

Mflv_2849|M.gilvum_PYR-GCK          LIKGPEVLESTRKVDTVVLDKTGTVTTGKMTLVDVVTAPGT---DRGNLL
MAV_5246|M.avium_104                LIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DRATLL
MSMEG_5014|M.smegmatis_MC2_155      LIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DRDDVL
TH_4361|M.thermoresistible__bu      LIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SETELL
Mvan_3670|M.vanbaalenii_PYR-1       LIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ---NSDELL
MAB_3984c|M.abscessus_ATCC_199      LIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADADEIL
MMAR_0264|M.marinum_M               FLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DADEVL
MUL_4850|M.ulcerans_Agy99           FLKGYQSLEATRSVDTVVFDKTGTLTSGQLKVSAVVAAPGW---DADEVL
Mb0095|M.bovis_AF2122/97            FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
Rv0092|M.tuberculosis_H37Rv         FLKGYKSLEATRAVDTVVFDKTGTLTTGRLQVSAVTAAPGW---EADQVL
MLBr_01987|M.leprae_Br4923          LLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGW---QANEVL
                                    ::** : :* .: :**:*:*****:*:* : :  *  . *    .   :*

Mflv_2849|M.gilvum_PYR-GCK          RLAGALENASEHPIAQAVATAATEELGTLPTPEDFANVEGKGVQGIVDGH
MAV_5246|M.avium_104                RYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRVDGH
MSMEG_5014|M.smegmatis_MC2_155      RVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTVEGR
TH_4361|M.thermoresistible__bu      RLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRVDGH
Mvan_3670|M.vanbaalenii_PYR-1       EFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTGVVAGH
MAB_3984c|M.abscessus_ATCC_199      RIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGVVDGQ
MMAR_0264|M.marinum_M               AIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGTVSGR
MUL_4850|M.ulcerans_Agy99           AIAATVEAASEHSVALAIAAATTQHD----TVTEFRAIPGRGVSGTVSGR
Mb0095|M.bovis_AF2122/97            ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
Rv0092|M.tuberculosis_H37Rv         ALAATVEAASEHSVALAIAAATTRRD----AVTDFRAIPGRGVSGTVSGR
MLBr_01987|M.leprae_Br4923          QMAATVESASEHAVALAIAASTTHRE----PVANFRAVPGHGVSGTVAER
                                      *.::* **:*.:* *:.  :            *    * ** * *  :

Mflv_2849|M.gilvum_PYR-GCK          AVVVGRESLLAD-WSQHLSPELARAKASAEAQGKTAVAVGWDGEARGVLV
MAV_5246|M.avium_104                AVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILA
MSMEG_5014|M.smegmatis_MC2_155      AVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGVLV
TH_4361|M.thermoresistible__bu      DVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAGVIV
Mvan_3670|M.vanbaalenii_PYR-1       AVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAVRGVIV
MAB_3984c|M.abscessus_ATCC_199      EVSI-----------------------EAIEGQNTTAAVSWGGLRRGEIE
MMAR_0264|M.marinum_M               SVRVGKPSWIGS---SSSDAALRAARRNAESLGETAVFVEIDGAPCGVIA
MUL_4850|M.ulcerans_Agy99           SVRVGKPSWIGS---SSSDTALRAALRNAESLGETAVFVEIDGGPCGVIA
Mb0095|M.bovis_AF2122/97            AVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIA
Rv0092|M.tuberculosis_H37Rv         AVRVGKPSWIGS---SSCHPNMRAARRHAESLGETAVFVEVDGEPCGVIA
MLBr_01987|M.leprae_Br4923          AVRVGKPSWIAS---RCNSTTLVTARRNAELRGETAVFVEIDGEQCGVIA
                                     * :                        *    .* . *  .*   * : 

Mflv_2849|M.gilvum_PYR-GCK          VADTVKPTSAQAISQMREIGLTPVLLTGDNEAVARQIAAEVGID--TVIA
MAV_5246|M.avium_104                LADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--EVIS
MSMEG_5014|M.smegmatis_MC2_155      VADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--DVYA
TH_4361|M.thermoresistible__bu      VSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--DVIA
Mvan_3670|M.vanbaalenii_PYR-1       VADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDPDDVIA
MAB_3984c|M.abscessus_ATCC_199      VADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGDVIA
MMAR_0264|M.marinum_M               VADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--EVIA
MUL_4850|M.ulcerans_Agy99           VADAVKDSAADAVAALRERGLRTMLLTGDNPASAAAVADRVGID--EVIA
Mb0095|M.bovis_AF2122/97            VADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIA
Rv0092|M.tuberculosis_H37Rv         VADAVKDSARDAVAALADRGLRTMLLTGDNPESAAAVATRVGID--EVIA
MLBr_01987|M.leprae_Br4923          VADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGID--EVIA
                                    ::*:**  :  *:  :   *  . :*****   *   * .:**    * :

Mflv_2849|M.gilvum_PYR-GCK          EVMPKDKVDVIVRLQAEGKTVAMVGDGVNDAPALAQADLGLAMGTGTDVA
MAV_5246|M.avium_104                GALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVA
MSMEG_5014|M.smegmatis_MC2_155      EVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTDVA
TH_4361|M.thermoresistible__bu      GVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGTDVA
Mvan_3670|M.vanbaalenii_PYR-1       EVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGTGSDVA
MAB_3984c|M.abscessus_ATCC_199      GVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGTDAA
MMAR_0264|M.marinum_M               NILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVA
MUL_4850|M.ulcerans_Agy99           NILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALASADLGMAMGRGTDVA
Mb0095|M.bovis_AF2122/97            DILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVA
Rv0092|M.tuberculosis_H37Rv         DILPEGKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVA
MLBr_01987|M.leprae_Br4923          DILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTDVA
                                       *  *.: :  *:  *: ***:***:**..**. **:*:::* *:*.*

Mflv_2849|M.gilvum_PYR-GCK          IEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFVYNVAAIPVAAL
MAV_5246|M.avium_104                IEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAAL
MSMEG_5014|M.smegmatis_MC2_155      IEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLAAA
TH_4361|M.thermoresistible__bu      IEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLAAA
Mvan_3670|M.vanbaalenii_PYR-1       IEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAALPLAAL
MAB_3984c|M.abscessus_ATCC_199      IEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPLAAL
MMAR_0264|M.marinum_M               IGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPIAAA
MUL_4850|M.ulcerans_Agy99           IGAADIILVRDNLDVVPLALGLAAATMRTVKLNLAWAFGYNIAAIPIAAA
Mb0095|M.bovis_AF2122/97            IGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAA
Rv0092|M.tuberculosis_H37Rv         IGAADIILVRDHLDVVPLALDLARATMRTVKLNMVWAFGYNIAAIPVAAA
MLBr_01987|M.leprae_Br4923          IGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIPIAAA
                                    * *.*: :* ..*  .  :: *.  *: *:* *: *** ** **:*:** 

Mflv_2849|M.gilvum_PYR-GCK          GMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSTSSAPTH----------
MAV_5246|M.avium_104                GMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA--------------
MSMEG_5014|M.smegmatis_MC2_155      GLLNPMLAGAAMAFSSVFVVSNSLRLKRFR--------------------
TH_4361|M.thermoresistible__bu      GLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR-----------------
Mvan_3670|M.vanbaalenii_PYR-1       GLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVATVPPGG
MAB_3984c|M.abscessus_ATCC_199      GLLNPMIAGAAMAMSSVFVVLNSLRLRTFR--------------------
MMAR_0264|M.marinum_M               GVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT-------TTS
MUL_4850|M.ulcerans_Agy99           GVLNPVVAGAAMAFSSFFVVSNSLQLRNFG----AATSQT-------TTS
Mb0095|M.bovis_AF2122/97            GLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG-------GPQ
Rv0092|M.tuberculosis_H37Rv         GLLNPLVAGAAMAFSSFFVVSNSLRLRKFGRYPLGCGTVG-------GPQ
MLBr_01987|M.leprae_Br4923          GLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRWRCPP
                                    *:***::******:**.:** ***:*: *                     

Mflv_2849|M.gilvum_PYR-GCK          --------------------------------
MAV_5246|M.avium_104                --------------------------------
MSMEG_5014|M.smegmatis_MC2_155      --------------------------------
TH_4361|M.thermoresistible__bu      --------------------------------
Mvan_3670|M.vanbaalenii_PYR-1       DEYRRAHTAP----------------------
MAB_3984c|M.abscessus_ATCC_199      --------------------------------
MMAR_0264|M.marinum_M               TTEPGATE------------------------
MUL_4850|M.ulcerans_Agy99           TTEPGATE------------------------
Mb0095|M.bovis_AF2122/97            MTAPSSA-------------------------
Rv0092|M.tuberculosis_H37Rv         MTAPSSA-------------------------
MLBr_01987|M.leprae_Br4923          PTRLRSTACSPVDASPLRPVAHRTGVKPPTHR