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VVRPSTPVRSPTDRRQPQRSDLRRTAILEALNEHLQKTGFDALNIAEVARQAGVGRSAFYFYFENKAAAV AALLEPMHEALLAANNILADLTRPPGERIRATLDAVLRTAEDHRYLFQAMLEARGTSGAVRDMWDAARES FVPTVSAVITAERESGRAPDGVDPKVLASLLMEFNDRLLERLIIGGPLTRRQLLEGAEAMWMGAIYASEP EQTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3874 | - | - | 100% (214) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6441 | - | 4e-19 | 26.85% (216) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1967 | - | 1e-14 | 33.82% (136) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 4e-15 | 27.86% (201) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_3103 | - | 3e-73 | 62.93% (205) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 4e-15 | 27.86% (201) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_01070 | - | 3e-17 | 28.37% (208) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0984c | - | 9e-15 | 28.71% (209) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1635 | - | 6e-15 | 30.24% (205) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0173 | - | 2e-19 | 31.22% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3269 | - | 3e-70 | 66.83% (199) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3401 | - | 4e-15 | 30.24% (205) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3432 | - | 1e-72 | 63.46% (208) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3103|M.gilvum_PYR-GCK --------MRS----PTDRRQPQKS-DLRRVAILESLNHHLRESGFDALN
Mvan_3432|M.vanbaalenii_PYR-1 --MQRGLPVRS----PTDRRQPQKS-DLRRSAILESLDQHLRESGFDGLN
MSMEG_3874|M.smegmatis_MC2_155 -MVRPSTPVRS----PTDRRQPQRS-DLRRTAILEALNEHLQKTGFDALN
TH_3269|M.thermoresistible__bu -MAQHGLSVRS----PTDRRQPLRS-DQRRTAILAALDEQLRVTGFERLN
Mb3885|M.bovis_AF2122/97 -MTTSAASQAS---LPRGRRTARPSGDDRELAILATAENLLEDRPLADIS
Rv3855|M.tuberculosis_H37Rv -MTTSAASQAS---LPRGRRTARPSGDDRELAILATAENLLEDRPLADIS
MAV_0173|M.avium_104 -MTT--AGQTR---ALRGRRAIRPTGDEREQAILATALRLLETRPFAGIS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
MAB_0984c|M.abscessus_ATCC_199 -MTKP---------ATRGRKTTRPSGDERIQAILATAEELLGKRPLADVS
MMAR_1635|M.marinum_M -MVNGQAADEK-----QRGPTLRRRGDKQRQAILQAVRELLEERPFAELS
MUL_3401|M.ulcerans_Agy99 -MVNGQAADEK-----QRGPTLRRRGDKQRQAILQAVRELLEERPFAELS
* : *** . * : ..
Mflv_3103|M.gilvum_PYR-GCK IAAVAKRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLASDILTDTTQP
Mvan_3432|M.vanbaalenii_PYR-1 IADVTRRAGVTRSAFYFYFENKAAAVAALLEPMYDDGFLAGDLLANIEQP
MSMEG_3874|M.smegmatis_MC2_155 IAEVARQAGVGRSAFYFYFENKAAAVAALLEPMHEALLAANNILADLTRP
TH_3269|M.thermoresistible__bu IAEVARQAGVTRSAFYFYFENKAAAVAALLDPMYDDVFAANDLLT-ADGD
Mb3885|M.bovis_AF2122/97 VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPAD
Rv3855|M.tuberculosis_H37Rv VDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPAD
MAV_0173|M.avium_104 VDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGAVQR-LP
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQ-LP
MAB_0984c|M.abscessus_ATCC_199 VDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASIDPA-AM
MMAR_1635|M.marinum_M VATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQYFAPRQPG
MUL_3401|M.ulcerans_Agy99 VATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQYFAPRQPG
: ::. **: *. ***** .* :.: *
Mflv_3103|M.gilvum_PYR-GCK PARR--VRAMLEALLDTVDEHRYLLQAMLEARATSAAIRHVWDEARETFV
Mvan_3432|M.vanbaalenii_PYR-1 PRAR--IRAMLEALLDTVDQHRYLLQAMLEARASSTVIREVWDDARESFV
MSMEG_3874|M.smegmatis_MC2_155 PGER--IRATLDAVLRTAEDHRYLFQAMLEARGTSGAVRDMWDAARESFV
TH_3269|M.thermoresistible__bu PRQR--IRAMIETLLDTGERHRYLLQAMLEARAVSSSVRTLWDTARESFV
Mb3885|M.bovis_AF2122/97 TDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWI
Rv3855|M.tuberculosis_H37Rv TDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWI
MAV_0173|M.avium_104 TDPRRVWRNGIKAFFTAFSSHRALARAATEALATSSELRSVWSGFMQKWI
MLBr_01070|M.leprae_Br4923 ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWI
MAB_0984c|M.abscessus_ATCC_199 TSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRWSEVTENWV
MMAR_1635|M.marinum_M ESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDILDQQFDVVL
MUL_3401|M.ulcerans_Agy99 ESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDILDQQFDVVL
: : . : : * . : . : :
Mflv_3103|M.gilvum_PYR-GCK PTVAQMIASERAAGRA-PDGPGPEMIAGILLEFNDRLMERHTLG--GRLS
Mvan_3432|M.vanbaalenii_PYR-1 PTVARMITAERDSGRA-PAGSSAEVVASMLLEFNDRLMERHTLG--GRLG
MSMEG_3874|M.smegmatis_MC2_155 PTVSAVITAERESGRA-PDGVDPKVLASLLMEFNDRLLERLIIG--GPLT
TH_3269|M.thermoresistible__bu PAVAAMIRTERSAGRA-PDGCDPVVLATALLEFNDRLLERFTAG--TALS
Mb3885|M.bovis_AF2122/97 AYTAAVIDAERDRGAA-PRTLPAHELATALNLMNERTLFASFAGEQPSVP
Rv3855|M.tuberculosis_H37Rv AYTAAVIDAERDRGAA-PRTLPAHELATALNLMNERTLFASFAGEQPSVP
MAV_0173|M.avium_104 DQTAAMITAERERGAA-PDTIPAADLATSLNQMNERTMMAALSAETPAVA
MLBr_01070|M.leprae_Br4923 DYNTAAIQAERKCGVA-PDTIPAEDLAVALQLMTERVMAATFSDEKPLIP
MAB_0984c|M.abscessus_ATCC_199 ANTTVGIEAERARGAA-PSVVPARDIAIALNLINQAMMRATFTGQQPAVD
MMAR_1635|M.marinum_M REIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDALLVGRDSD
MUL_3401|M.ulcerans_Agy99 REIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDALLVGRDSD
* :* * * * : * . :
Mflv_3103|M.gilvum_PYR-GCK RDELLTAAQSVWLRTIYAN---------DGDELQ----------
Mvan_3432|M.vanbaalenii_PYR-1 RDELLAGAETIWLRTIYAH---------DGDL------------
MSMEG_3874|M.smegmatis_MC2_155 RRQLLEGAEAMWMGAIYAS---------EPEQTR----------
TH_3269|M.thermoresistible__bu RQQLRDGAEAVWLGSIYPGPIGGPGPRPDPRPDRHPESTPSSRF
Mb3885|M.bovis_AF2122/97 EARVLDTLVHIWVTSIYGENR-----------------------
Rv3855|M.tuberculosis_H37Rv EARVLDTLVHIWVTSIYGENR-----------------------
MAV_0173|M.avium_104 EDRVVDTLTHIWVSSIYGESG-----------------------
MLBr_01070|M.leprae_Br4923 DKKVIDTLVHIWLASIYGS-------------------------
MAB_0984c|M.abscessus_ATCC_199 DGKVVDTLLHVWLNAIYGGVCANS--------------------
MMAR_1635|M.marinum_M LERRVRVLEQMWLNALWGGPIRT---------------------
MUL_3401|M.ulcerans_Agy99 LERRVRVLEQMWLNALWGGPIRT---------------------
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