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M. ulcerans Agy99 MUL_4845 (ctpB)

annotation: cation-transporter p-type ATPase B CtpB
coordinates: 5366880 - 5369153
length: 757

VAAPITGDLDLGSARRIQLDVSGMSCAACASRVETKLNKVPGVRASVNFATRVATIDAVDVAADELCELV
EKAGYQAVPHAESAADDRDPDAEHARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWGYLLTALAAP
IVIWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLSTVFVDRQPRQSRGIWQAILNSDSIYLEVA
AGVTVFVLAGRYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFVTRPGQTIAAD
GVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGRLVIEATAVGADTQFAAMVRLVEEAQAQKAR
AQRLADRISAVFVPVVFAIAGVAGVAWMLSGAGADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGAQ
LGIFIKGYQALETIHGIDAVVFEKTGTLTVGKLTVNTVTTTGGRVREEVLALASAVEAASEHAVATAIVA
ASPHPAPVTDFVAVAGCGVSRIVDGHRIEVGKPSWITRNTAADEVLDTARAQGESRGETIVFVSVDGEVC
AAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAVADSVATQLGIDTAIADVLPDGKVNVIRQLRDQG
HTVAMVGDGINDGPALVSADLGLAIGRGTDVAIGAADIILVRDDLHIVGQALDLARATMRTIRTNMIWAF
GYNVAAIPIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4845ctpB-100% (757)cation-transporter p-type ATPase B CtpB
M. ulcerans Agy99MUL_4850ctpA0.067.34% (741) cation transporter p-type ATPase a CtpA
M. ulcerans Agy99MUL_0423ctpVe-14645.88% (656) metal cation transporter p-type ATPase, CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0106cctpB0.081.60% (750) cation-transporter P-type ATPase B
M. gilvum PYR-GCKMflv_0912-0.050.13% (756) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0103cctpB0.081.47% (750) cation-transporter P-type ATPase B
M. leprae Br4923MLBr_02000ctpB0.078.77% (730) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-16746.17% (745) putative metal transporter ATPase
M. marinum MMMAR_0269ctpB0.098.68% (757) cation-transporter p-type ATPase B CtpB
M. avium 104MAV_5246-0.047.93% (747) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.049.26% (741) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.050.85% (761) PUTATIVE heavy metal translocating P-type ATPase
M. vanbaalenii PYR-1Mvan_3670-0.051.25% (761) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0912|M.gilvum_PYR-GCK          MALMT------TSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
MUL_4845|M.ulcerans_Agy99           ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR
MMAR_0269|M.marinum_M               ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR
Mb0106c|M.bovis_AF2122/97           ----MAAPVVGDAD--LQSVRRIRLDVSGMSCAACASRVETKLNKIPGVR
Rv0103c|M.tuberculosis_H37Rv        ----MAAPVVGDAD--LQSVRRIRLDVLGMSCAACASRVETKLNKIPGVR
MLBr_02000|M.leprae_Br4923          ----MTASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
                                                            * : ** **:** *:*  **:: ** 

Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPR-------
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
MUL_4845|M.ulcerans_Agy99           ASVNFATRVATIDAVD-VAADELCELVEKAGYQAVPHAESAADDR---DP
MMAR_0269|M.marinum_M               ASVNFATRVATIDAVD-VAADQLCELVEKAGYQAVPHAESAADDR---DP
Mb0106c|M.bovis_AF2122/97           ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP
Rv0103c|M.tuberculosis_H37Rv        ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP
MLBr_02000|M.leprae_Br4923          ASVNFATRVATIDAVD-VAVDELRQVIEQAGYRATAHAESAVEEI---DP
                                    * ** * . * :          *   :* .** *                

Mflv_0912|M.gilvum_PYR-GCK          TPNADGI--DDPELASLRHRLRASTVLTVPVIAMA----MIPALQFTYWQ
MAV_5246|M.avium_104                ---------DDPELASLRRRLVTAIALAGPVIAVA----MIPALQFQHWH
MSMEG_5014|M.smegmatis_MC2_155      P--------EDRATDALRTRLLVSAVLTVPVIAMA----MVPALQFTNWQ
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLS----MIPALQFTHWQ
Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVPVIAMS----MIPALQFTNWQ
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVIS----MAMPLHFSGWE
MUL_4845|M.ulcerans_Agy99           DAE---------HARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG
MMAR_0269|M.marinum_M               DAE---------HARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG
Mb0106c|M.bovis_AF2122/97           DGA---------HARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG
Rv0103c|M.tuberculosis_H37Rv        DGA---------HARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG
MLBr_02000|M.leprae_Br4923          DAD---------YARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWG
                                                       **  :  *  *:  ::    :  . :.  * 

Mflv_0912|M.gilvum_PYR-GCK          WASLTLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLY
MAV_5246|M.avium_104                WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
MSMEG_5014|M.smegmatis_MC2_155      WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
TH_4361|M.thermoresistible__bu      WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
Mvan_3670|M.vanbaalenii_PYR-1       WLALTLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199      ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
MUL_4845|M.ulcerans_Agy99           YLLTALAAPIVIWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS
MMAR_0269|M.marinum_M               YLLTALAAPIVTWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS
Mb0106c|M.bovis_AF2122/97           YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS
Rv0103c|M.tuberculosis_H37Rv        YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS
MLBr_02000|M.leprae_Br4923          YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLS
                                        :*::*:: * . *** .*  * :: .::*:**:* *  :*  *** 

Mflv_0912|M.gilvum_PYR-GCK          ALFFGTAGTPGMKHPFELTLAP----SHGAA--NIYLEVAAGVTTFILAG
MAV_5246|M.avium_104                ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
MSMEG_5014|M.smegmatis_MC2_155      ALFWGTAGVPGMTHPFSLVGSR----TDGAG--NIYLEVAAGVTTFILAG
TH_4361|M.thermoresistible__bu      ALFFTAAGMPGMTMTFTLLP-AD------TGEPHIYLEVAAAVTTFIIAG
Mvan_3670|M.vanbaalenii_PYR-1       ALFIGHAGMPGMRMAFSLLPDAG------SETEHIYLEVAAAVTVFILAG
MAB_3984c|M.abscessus_ATCC_199      VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
MUL_4845|M.ulcerans_Agy99           TVFVDRQPRQSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG
MMAR_0269|M.marinum_M               TVFVDRQPRHSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG
Mb0106c|M.bovis_AF2122/97           SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG
Rv0103c|M.tuberculosis_H37Rv        SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG
MLBr_02000|M.leprae_Br4923          TIFVDKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAG
                                     :.                               :*:**.*.** *::**

Mflv_0912|M.gilvum_PYR-GCK          RYFEKRSKRQAGAALRALLNLGAKDVSVLR-DGVETKIAIEELMVGDEFV
MAV_5246|M.avium_104                RYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFV
MSMEG_5014|M.smegmatis_MC2_155      RYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFV
TH_4361|M.thermoresistible__bu      RYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFV
Mvan_3670|M.vanbaalenii_PYR-1       RYFEARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFV
MAB_3984c|M.abscessus_ATCC_199      RFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFV
MUL_4845|M.ulcerans_Agy99           RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV
MMAR_0269|M.marinum_M               RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV
Mb0106c|M.bovis_AF2122/97           RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV
Rv0103c|M.tuberculosis_H37Rv        RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV
MLBr_02000|M.leprae_Br4923          RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFL
                                    *: * ::*  :..*****   **::* ::   * *  :.  .*   : *:

Mflv_0912|M.gilvum_PYR-GCK          VRPGEKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGR
MAV_5246|M.avium_104                VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
MSMEG_5014|M.smegmatis_MC2_155      VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
TH_4361|M.thermoresistible__bu      VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
Mvan_3670|M.vanbaalenii_PYR-1       VRPGEKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGR
MAB_3984c|M.abscessus_ATCC_199      VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
MUL_4845|M.ulcerans_Agy99           TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR
MMAR_0269|M.marinum_M               TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR
Mb0106c|M.bovis_AF2122/97           TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR
Rv0103c|M.tuberculosis_H37Rv        TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR
MLBr_02000|M.leprae_Br4923          VRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGR
                                    .***: :::** *  * :::* : :***: *:..     * *.     *:

Mflv_0912|M.gilvum_PYR-GCK          LVVRASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIA
MAV_5246|M.avium_104                LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
MSMEG_5014|M.smegmatis_MC2_155      LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
TH_4361|M.thermoresistible__bu      LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
Mvan_3670|M.vanbaalenii_PYR-1       LLVRATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALS
MAB_3984c|M.abscessus_ATCC_199      IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
MUL_4845|M.ulcerans_Agy99           LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA
MMAR_0269|M.marinum_M               LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA
Mb0106c|M.bovis_AF2122/97           LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA
Rv0103c|M.tuberculosis_H37Rv        LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA
MLBr_02000|M.leprae_Br4923          LVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA
                                    : :.*. :* ***:* *..**  **  ** .*:***:::.****:*: ::

Mflv_0912|M.gilvum_PYR-GCK          VITLGAWLGAGFS-VTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGA
MAV_5246|M.avium_104                VATLAGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MSMEG_5014|M.smegmatis_MC2_155      VATLGFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
TH_4361|M.thermoresistible__bu      ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
Mvan_3670|M.vanbaalenii_PYR-1       VATLAAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
MAB_3984c|M.abscessus_ATCC_199      ALTFVAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
MUL_4845|M.ulcerans_Agy99           GVAGVAWMLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
MMAR_0269|M.marinum_M               GLAGAAWLLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
Mb0106c|M.bovis_AF2122/97           GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
Rv0103c|M.tuberculosis_H37Rv        GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
MLBr_02000|M.leprae_Br4923          GLAGASWLLAGAS-PDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA
                                      :   *          *::..:.**:*****:********::*.:**.*

Mflv_0912|M.gilvum_PYR-GCK          QMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT----E
MAV_5246|M.avium_104                QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT----D
MSMEG_5014|M.smegmatis_MC2_155      QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE----D
TH_4361|M.thermoresistible__bu      QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL----S
Mvan_3670|M.vanbaalenii_PYR-1       QLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ----N
MAB_3984c|M.abscessus_ATCC_199      QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGV-AD
MUL_4845|M.ulcerans_Agy99           QLGIFIKGYQALETIHGIDAVVFEKTGTLTVGKLTVNTVTTTGG----RV
MMAR_0269|M.marinum_M               QLGIFIKGYQALETIHGIDAVVFDKTGTLTVGKLTVNTVTTTGG----RV
Mb0106c|M.bovis_AF2122/97           QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD
Rv0103c|M.tuberculosis_H37Rv        QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD
MLBr_02000|M.leprae_Br4923          QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGG----WC
                                    *:*::*** ..**. . :*::*::****:* * :::  *    .      

Mflv_0912|M.gilvum_PYR-GCK          RAELLRLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQG
MAV_5246|M.avium_104                RATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHG
MSMEG_5014|M.smegmatis_MC2_155      RDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQG
TH_4361|M.thermoresistible__bu      ETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSG
Mvan_3670|M.vanbaalenii_PYR-1       SDELLEFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTG
MAB_3984c|M.abscessus_ATCC_199      ADEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSG
MUL_4845|M.ulcerans_Agy99           REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSR
MMAR_0269|M.marinum_M               REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSG
Mb0106c|M.bovis_AF2122/97           REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG
Rv0103c|M.tuberculosis_H37Rv        REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG
MLBr_02000|M.leprae_Br4923          SGEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSG
                                       :*  *.::* **:*.:* *:.              .*    * **  

Mflv_0912|M.gilvum_PYR-GCK          VVDGHAVVVGRESLLAD-WAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQA
MAV_5246|M.avium_104                RVDGHAVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRA
MSMEG_5014|M.smegmatis_MC2_155      TVEGRAVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTA
TH_4361|M.thermoresistible__bu      RVDGHDVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRI
Mvan_3670|M.vanbaalenii_PYR-1       VVAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAV
MAB_3984c|M.abscessus_ATCC_199      VVDGQEVSI-----------------------EAIEGQNTTAAVSWGGLR
MUL_4845|M.ulcerans_Agy99           IVDGHRIEVGKPSWITR-NT-AADEVLDTARAQGESRGETIVFVSVDGEV
MMAR_0269|M.marinum_M               IVDGHRIEVGKPSWITR-NT-AADEVLDTARAQGESRGETIVFVSVDGEV
Mb0106c|M.bovis_AF2122/97           EVGGHHVEVGKPSWITR-TTPCHDAALVSARLDGESRGETVVFVSVDGVV
Rv0103c|M.tuberculosis_H37Rv        EVGGHHVEVGKPSWITR-TTPCHDAALVSARLDGESRGETVVFVSVDGVV
MLBr_02000|M.leprae_Br4923          VVAEHHVKIGKPSWVTR-NA-PCDVVLESARREGESRGETVVFVSVDGVA
                                     *  : : :                        .    .* . *. .*  

Mflv_0912|M.gilvum_PYR-GCK          RGVLVVADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID-
MAV_5246|M.avium_104                RGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG-
MSMEG_5014|M.smegmatis_MC2_155      RGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID-
TH_4361|M.thermoresistible__bu      AGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID-
Mvan_3670|M.vanbaalenii_PYR-1       RGVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDP
MAB_3984c|M.abscessus_ATCC_199      RGEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAA
MUL_4845|M.ulcerans_Agy99           CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAVADSVATQLGID-
MMAR_0269|M.marinum_M               CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAAADSVATQLGID-
Mb0106c|M.bovis_AF2122/97           RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID-
Rv0103c|M.tuberculosis_H37Rv        RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID-
MLBr_02000|M.leprae_Br4923          CGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID-
                                     . : ::*::*  :  *:  :   *  ..:*****  .*   * ::**  

Mflv_0912|M.gilvum_PYR-GCK          -TVIAEVMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGT
MAV_5246|M.avium_104                -EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGT
MSMEG_5014|M.smegmatis_MC2_155      -DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGT
TH_4361|M.thermoresistible__bu      -DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGT
Mvan_3670|M.vanbaalenii_PYR-1       DDVIAEVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGT
MAB_3984c|M.abscessus_ATCC_199      GDVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGT
MUL_4845|M.ulcerans_Agy99           -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR
MMAR_0269|M.marinum_M               -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR
Mb0106c|M.bovis_AF2122/97           -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR
Rv0103c|M.tuberculosis_H37Rv        -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR
MLBr_02000|M.leprae_Br4923          -TVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGR
                                      . :   *  *.: :  *:  *: ***:***:**..**. **:*:::* 

Mflv_0912|M.gilvum_PYR-GCK          GTDVAIEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAI
MAV_5246|M.avium_104                GTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAI
MSMEG_5014|M.smegmatis_MC2_155      GTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAAL
TH_4361|M.thermoresistible__bu      GTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAAL
Mvan_3670|M.vanbaalenii_PYR-1       GSDVAIEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAAL
MAB_3984c|M.abscessus_ATCC_199      GTDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAI
MUL_4845|M.ulcerans_Agy99           GTDVAIGAADIILVRDDLHIVGQALDLARATMRTIRTNMIWAFGYNVAAI
MMAR_0269|M.marinum_M               GTDVAIGAADIILVRDDLHIVGQALDLARATLRTIRTNMIWAFGYNVAAI
Mb0106c|M.bovis_AF2122/97           GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI
Rv0103c|M.tuberculosis_H37Rv        GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI
MLBr_02000|M.leprae_Br4923          GTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAI
                                    *:*.*: *.*: :* ..*  .  *: *.* *: **: *:.***.** **:

Mflv_0912|M.gilvum_PYR-GCK          PVAALGMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH-------
MAV_5246|M.avium_104                PLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA---------
MSMEG_5014|M.smegmatis_MC2_155      PLAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR---------------
TH_4361|M.thermoresistible__bu      PLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR------------
Mvan_3670|M.vanbaalenii_PYR-1       PLAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVAT
MAB_3984c|M.abscessus_ATCC_199      PLAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR---------------
MUL_4845|M.ulcerans_Agy99           PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD
MMAR_0269|M.marinum_M               PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD
Mb0106c|M.bovis_AF2122/97           PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ-------------
Rv0103c|M.tuberculosis_H37Rv        PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ-------------
MLBr_02000|M.leprae_Br4923          PIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD---------
                                    *:*: *:***::******:**.:** *****  *                

Mflv_0912|M.gilvum_PYR-GCK          ---------------
MAV_5246|M.avium_104                ---------------
MSMEG_5014|M.smegmatis_MC2_155      ---------------
TH_4361|M.thermoresistible__bu      ---------------
Mvan_3670|M.vanbaalenii_PYR-1       VPPGGDEYRRAHTAP
MAB_3984c|M.abscessus_ATCC_199      ---------------
MUL_4845|M.ulcerans_Agy99           ---------------
MMAR_0269|M.marinum_M               ---------------
Mb0106c|M.bovis_AF2122/97           ---------------
Rv0103c|M.tuberculosis_H37Rv        ---------------
MLBr_02000|M.leprae_Br4923          ---------------