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M. tuberculosis H37Rv Rv0103c (ctpB)

annotation: PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB
coordinates: 119915 - 122173
length: 752

AAPVVGDADLQSVRRIRLDVLGMSCAACASRVETKLNKIPGVRASVNFATRVATIDAVGMAADELCGVVE
KAGYHAAPHTETTVLDKRTKDPDGAHARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWGYILTALA
APVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLSSVFGDQPPREGSGIWRAILNSDSIYLE
VAAGVTVFVLAGRYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFVTRPGETIA
ADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGRLVIEATAVGADTQFAAMVRLVEQAQTQK
ARAQRLADHIAGVFVPVVFVIAGLAGAAWLVSGAGADRAFSVTLGVLVIACPCALGLATPTAMMVASGRG
AQLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERDREEVLGLAAAVESASEHAM
AAAIVAASPDPGPVNGFVAVAGCGVSGEVGGHHVEVGKPSWITRTTPCHDAALVSARLDGESRGETVVFV
SVDGVVRAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGIDSAVADMLPEGKVDVI
QRLREEGHTVAMVGDGINDGPALVGADLGLAIGRGTDVALGAADIILVRDDLNTVPQALDLARATMRTIR
MNMIWAFGYNVAAIPIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0103cctpB-100% (752)PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB
M. tuberculosis H37RvRv0092ctpA0.068.15% (741) cation transporter P-type ATPase A
M. tuberculosis H37RvRv0969ctpVe-15147.12% (660) metal cation transporter P-type ATPase CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0106cctpB0.099.87% (752) cation-transporter P-type ATPase B
M. gilvum PYR-GCKMflv_0912-0.050.73% (751) heavy metal translocating P-type ATPase
M. leprae Br4923MLBr_02000ctpB0.077.13% (752) cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-16946.52% (748) putative metal transporter ATPase
M. marinum MMMAR_0269ctpB0.082.13% (750) cation-transporter p-type ATPase B CtpB
M. avium 104MAV_5246-0.049.27% (755) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.050.74% (747) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.050.86% (753) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_4845ctpB0.081.47% (750) cation-transporter p-type ATPase B CtpB
M. vanbaalenii PYR-1Mvan_3670-0.051.20% (748) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0912|M.gilvum_PYR-GCK          MALMT------TSTSTPVSGANVELRIGGMTCASCANRIERKLNKLDGVA
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAARIEKKLNKLDGVT
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAARIERKLNKLDGVT
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAARVEKRLNRIDGVV
Mvan_3670|M.vanbaalenii_PYR-1       -------MSLPNHIVGVDQPHSIELSIGGMTCASCAARIEKKLNKIDGVE
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASRVEKGLNKITGVN
Rv0103c|M.tuberculosis_H37Rv        ----MAAPVVGDAD--LQSVRRIRLDVLGMSCAACASRVETKLNKIPGVR
Mb0106c|M.bovis_AF2122/97           ----MAAPVVGDAD--LQSVRRIRLDVSGMSCAACASRVETKLNKIPGVR
MMAR_0269|M.marinum_M               ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR
MUL_4845|M.ulcerans_Agy99           ----MAAPITGDLD--LGSARRIQLDVSGMSCAACASRVETKLNKVPGVR
MLBr_02000|M.leprae_Br4923          ----MTASLVEDTNNNHESVRRIQLDVAGMLCAACASRVETKLNKIPGVR
                                                            * : ** **:** *:*  **:: ** 

Mflv_0912|M.gilvum_PYR-GCK          ATVNYATEKATVTVPDGYDPALLIAEVEKTGYTATLPTPRAPAPSDASGD
MAV_5246|M.avium_104                ATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVATPSPPR-------
MSMEG_5014|M.smegmatis_MC2_155      ASVNYATEKASVEVAGEVSPETLIEVVETAGYTAHLPAPPQPETGGTEQD
TH_4361|M.thermoresistible__bu      ATVNFATEQATVRYPDHVDPADLIAAIEATGYTASLPAPQRDTGGAPAGA
Mvan_3670|M.vanbaalenii_PYR-1       ASVNYATEKAKVDYPNSVDPAVLIAAVEATGYTATAPAAPNDAAPTDSGP
MAB_3984c|M.abscessus_ATCC_199      ARVNLALESARVEHDGSVTGEDLVKAVESVGYTAQVVGGSHQDAHAGDHD
Rv0103c|M.tuberculosis_H37Rv        ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP
Mb0106c|M.bovis_AF2122/97           ASVNFATRVATIDAVG-MAADELCGVVEKAGYHAAPHTETTVLDKRTKDP
MMAR_0269|M.marinum_M               ASVNFATRVATIDAVD-VAADQLCELVEKAGYQAVPHAESAADDR---DP
MUL_4845|M.ulcerans_Agy99           ASVNFATRVATIDAVD-VAADELCELVEKAGYQAVPHAESAADDR---DP
MLBr_02000|M.leprae_Br4923          ASVNFATRVATIDAVD-VAVDELRQVIEQAGYRATAHAESAVEEI---DP
                                    * ** * . * :          *   :* .** *                

Mflv_0912|M.gilvum_PYR-GCK          TPNADGI--DDPELASLRHRLRASTVLTVPVIAMA----MIPALQFTYWQ
MAV_5246|M.avium_104                ---------DDPELASLRRRLVTAIALAGPVIAVA----MIPALQFQHWH
MSMEG_5014|M.smegmatis_MC2_155      P--------EDRATDALRTRLLVSAVLTVPVIAMA----MVPALQFTNWQ
TH_4361|M.thermoresistible__bu      ATGAAGDD-HDAEAERWRRRLTISAALSIPVVVLS----MIPALQFTHWQ
Mvan_3670|M.vanbaalenii_PYR-1       DAG---------EADSLRSRLLISLVLTVPVIAMS----MIPALQFTNWQ
MAB_3984c|M.abscessus_ATCC_199      GHDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVIS----MAMPLHFSGWE
Rv0103c|M.tuberculosis_H37Rv        DGA---------HARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG
Mb0106c|M.bovis_AF2122/97           DGA---------HARRLLRRLLVAAVLFVPLADLSTLFAIVPSARVPGWG
MMAR_0269|M.marinum_M               DAE---------HARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG
MUL_4845|M.ulcerans_Agy99           DAE---------HARTLLRRLLVAAVLFVPLADLSTMFALVPSTRFPGWG
MLBr_02000|M.leprae_Br4923          DAD---------YARNLLRRLIVAALLFVPLADLSTMFAIVPTNRFPGWG
                                                       **  :  *  *:  ::    :  . :.  * 

Mflv_0912|M.gilvum_PYR-GCK          WASLTLAAPVIVWAAWPFHRAAWANLRHGTATMDTLISLGTVSAFLWSLY
MAV_5246|M.avium_104                WAALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLY
MSMEG_5014|M.smegmatis_MC2_155      WLSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLY
TH_4361|M.thermoresistible__bu      WLALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLW
Mvan_3670|M.vanbaalenii_PYR-1       WLALTLASPVVVWGALPFHRAAWANARHRAATMDTLISLGVSAAYLWSLW
MAB_3984c|M.abscessus_ATCC_199      ILVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLW
Rv0103c|M.tuberculosis_H37Rv        YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS
Mb0106c|M.bovis_AF2122/97           YILTALAAPVVTWAAWPFHSVALRNARHRTTSMETLISVGIVAATAWSLS
MMAR_0269|M.marinum_M               YLLTALAAPIVTWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS
MUL_4845|M.ulcerans_Agy99           YLLTALAAPIVIWAAWPFHSVAIRNARHRTASMETLISVGITAATVWSLS
MLBr_02000|M.leprae_Br4923          YLLTALAAPIVTWAAWPFHRVALRNARYRAASMETLISAGILAATGWSLS
                                        :*::*:: * . *** .*  * :: .::*:**:* *  :*  *** 

Mflv_0912|M.gilvum_PYR-GCK          ALFFGTAGTPGMKHPFELTLAP----SHGAA--NIYLEVAAGVTTFILAG
MAV_5246|M.avium_104                ALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAG
MSMEG_5014|M.smegmatis_MC2_155      ALFWGTAGVPGMTHPFSLVGSR----TDGAG--NIYLEVAAGVTTFILAG
TH_4361|M.thermoresistible__bu      ALFFTAAGMPGMTMTFTLLP-AD------TGEPHIYLEVAAAVTTFIIAG
Mvan_3670|M.vanbaalenii_PYR-1       ALFIGHAGMPGMRMAFSLLPDAG------SETEHIYLEVAAAVTVFILAG
MAB_3984c|M.abscessus_ATCC_199      VLFANAGHTHGDVH--------------------VYFEVVAAVTVFLLAG
Rv0103c|M.tuberculosis_H37Rv        SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG
Mb0106c|M.bovis_AF2122/97           SVFGDQPPREGSGIWRAILNSDS-----------IYLEVAAGVTVFVLAG
MMAR_0269|M.marinum_M               TVFVDRQPRHSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG
MUL_4845|M.ulcerans_Agy99           TVFVDRQPRQSRGIWQAILNSDS-----------IYLEVAAGVTVFVLAG
MLBr_02000|M.leprae_Br4923          TIFVDKEPRQTHGIWQAILHSDS-----------IYFEVAAGVTVFVLAG
                                     :.                               :*:**.*.** *::**

Mflv_0912|M.gilvum_PYR-GCK          RYFEKRSKRQAGAALRALLNLGAKDVSVLR-DGVETKIAIEELMVGDEFV
MAV_5246|M.avium_104                RYFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFV
MSMEG_5014|M.smegmatis_MC2_155      RYFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFV
TH_4361|M.thermoresistible__bu      RYFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFV
Mvan_3670|M.vanbaalenii_PYR-1       RYFEARAKTRSGAALRALLDMGAKDVAVVR-NGTEIRIPTAELSVGDVFV
MAB_3984c|M.abscessus_ATCC_199      RFAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFV
Rv0103c|M.tuberculosis_H37Rv        RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV
Mb0106c|M.bovis_AF2122/97           RYFEARAKSKAGSALRALAELGAKNVAVLLPDGAELVIPASELKKRQRFV
MMAR_0269|M.marinum_M               RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV
MUL_4845|M.ulcerans_Agy99           RYFEARAKSKAGGALRALAALGAKDVTVLLPDGAELVIPAAELKKRQRFV
MLBr_02000|M.leprae_Br4923          RFFEARAKSKAGSALRALAARGAKNVEVLLPNGAELTIPAGELKKQQHFL
                                    *: * ::*  :..*****   **::* ::   * *  :.  .*   : *:

Mflv_0912|M.gilvum_PYR-GCK          VRPGEKIATDGVVTSGSSAVDASMLTGESVPVEVAAGDTVVGATVNAGGR
MAV_5246|M.avium_104                VRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGR
MSMEG_5014|M.smegmatis_MC2_155      VRPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGR
TH_4361|M.thermoresistible__bu      VRPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGH
Mvan_3670|M.vanbaalenii_PYR-1       VRPGEKIATDGVVTDGSSAVDASMLTGESVPVEVRPGDHVTGATVNAGGR
MAB_3984c|M.abscessus_ATCC_199      VRPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGR
Rv0103c|M.tuberculosis_H37Rv        TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR
Mb0106c|M.bovis_AF2122/97           TRPGETIAADGVVVDGSAAIDMSAMTGEAKPVRAYPAASVVGGTVVMDGR
MMAR_0269|M.marinum_M               TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR
MUL_4845|M.ulcerans_Agy99           TRPGQTIAADGVVIDGTAAIDMSAMTGESKPVRATADAPVIGGTIVLDGR
MLBr_02000|M.leprae_Br4923          VRPGETITADGVVIDGTATIDMSAITGEARPVHASPASTVVGGTTVLDGR
                                    .***: :::** *  * :::* : :***: *:..     * *.     *:

Mflv_0912|M.gilvum_PYR-GCK          LVVRASRVGSDTQLAQMAELVERAQTGKAEVQRLADRISGVFVPIVIAIA
MAV_5246|M.avium_104                LVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLA
MSMEG_5014|M.smegmatis_MC2_155      LVVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALA
TH_4361|M.thermoresistible__bu      LQVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALS
Mvan_3670|M.vanbaalenii_PYR-1       LLVRATRIGADTQLAQMARLVEDAQNGKASVQRLADRVSAVFVPIVLALS
MAB_3984c|M.abscessus_ATCC_199      IVVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAIS
Rv0103c|M.tuberculosis_H37Rv        LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA
Mb0106c|M.bovis_AF2122/97           LVIEATAVGADTQFAAMVRLVEQAQTQKARAQRLADHIAGVFVPVVFVIA
MMAR_0269|M.marinum_M               LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA
MUL_4845|M.ulcerans_Agy99           LVIEATAVGADTQFAAMVRLVEEAQAQKARAQRLADRISAVFVPVVFAIA
MLBr_02000|M.leprae_Br4923          LVIEATAVGGDTQFAAMVRLVEDAQVQKARVQHLADRIAAVFVPMVFVIA
                                    : :.*. :* ***:* *..**  **  ** .*:***:::.****:*: ::

Mflv_0912|M.gilvum_PYR-GCK          VITLGAWLGAGFS-VTAAFTAAVAVLVIACPCALGLATPTALLVGTGRGA
MAV_5246|M.avium_104                VATLAGWLAAGGT-LATALTAAVAVLIIACPCALGLATPTALLVGTGRAA
MSMEG_5014|M.smegmatis_MC2_155      VATLGFWLGTGGS-VAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
TH_4361|M.thermoresistible__bu      ALTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGA
Mvan_3670|M.vanbaalenii_PYR-1       VATLAAWLLTGHS-ATVAFTAAVAVLIIACPCALGLATPTALMVGTGRGA
MAB_3984c|M.abscessus_ATCC_199      ALTFVAWAALGNS-LASAFTAAVAVLIIACPCALGLATPTAILVGTGRGA
Rv0103c|M.tuberculosis_H37Rv        GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
Mb0106c|M.bovis_AF2122/97           GLAGAAWLVSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
MMAR_0269|M.marinum_M               GLAGAAWLLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
MUL_4845|M.ulcerans_Agy99           GVAGVAWMLSGAG-ADRAFSVTLGVLVIACPCALGLATPTAMMVASGRGA
MLBr_02000|M.leprae_Br4923          GLAGASWLLAGAS-PDRAFSVVLGVLVIACPCTLGLATPTAMMVASGRGA
                                      :   *          *::..:.**:*****:********::*.:**.*

Mflv_0912|M.gilvum_PYR-GCK          QMGVLIKGPEVLESTRKVDTVVLDKTGTVTTGKMALVDVIAAPGT----E
MAV_5246|M.avium_104                QLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT----D
MSMEG_5014|M.smegmatis_MC2_155      QLGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE----D
TH_4361|M.thermoresistible__bu      QLGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL----S
Mvan_3670|M.vanbaalenii_PYR-1       QLGILIKGPQVLESTRRVDTIVLDKTGTVTTGRMSLVGVHPGAGQ----N
MAB_3984c|M.abscessus_ATCC_199      QLGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGV-AD
Rv0103c|M.tuberculosis_H37Rv        QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD
Mb0106c|M.bovis_AF2122/97           QLGIFIKGYRALETIRSIDTVVFDKTGTLTVGQLAVSTVTMAGSGTSERD
MMAR_0269|M.marinum_M               QLGIFIKGYQALETIHGIDAVVFDKTGTLTVGKLTVNTVTTTGG----RV
MUL_4845|M.ulcerans_Agy99           QLGIFIKGYQALETIHGIDAVVFEKTGTLTVGKLTVNTVTTTGG----RV
MLBr_02000|M.leprae_Br4923          QLGIFIKGYRALETINAIDTVVFDKTGTLTLGQLSVSTVTSTGG----WC
                                    *:*::*** ..**. . :*::*::****:* * :::  *    .      

Mflv_0912|M.gilvum_PYR-GCK          RAELLRLAGALENASEHPIAHAIATAAAEEVGTLPTPEGFANVEGKGVQG
MAV_5246|M.avium_104                RATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHG
MSMEG_5014|M.smegmatis_MC2_155      RDDVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQG
TH_4361|M.thermoresistible__bu      ETELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSG
Mvan_3670|M.vanbaalenii_PYR-1       SDELLEFAGALESASQHPIAEAIAASAAAGG-TLPAVEDFSNHNGYGVTG
MAB_3984c|M.abscessus_ATCC_199      ADEILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSG
Rv0103c|M.tuberculosis_H37Rv        REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG
Mb0106c|M.bovis_AF2122/97           REEVLGLAAAVESASEHAMAAAIVAASPDPG----PVNGFVAVAGCGVSG
MMAR_0269|M.marinum_M               REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSG
MUL_4845|M.ulcerans_Agy99           REEVLALASAVEAASEHAVATAIVAASPHPA----PVTDFVAVAGCGVSR
MLBr_02000|M.leprae_Br4923          SGEVLALASAVEAASEHSVATAIVAAYADPR----PVADFVAFAGCGVSG
                                       :*  *.::* **:*.:* *:.              .*    * **  

Mflv_0912|M.gilvum_PYR-GCK          VVDGHAVVVGRESLLAD-WAQHLSPDLSRAKAGAEAQGKTVVAVGWDGQA
MAV_5246|M.avium_104                RVDGHAVAIGRPSWLAE-RGLRPDAALAAAAARAEHDGKTVVAVGWDGRA
MSMEG_5014|M.smegmatis_MC2_155      TVEGRAVVVGRPRLFGD-PEKSLPRKLADAMEAAQAQGRTAVVVGWDGTA
TH_4361|M.thermoresistible__bu      RVDGHDVRVGRLAWLG----LSAGDRLRNAAAQAEAAGHTPVWVAVDGRI
Mvan_3670|M.vanbaalenii_PYR-1       VVAGHAVLVGRLSWLTDDWSLTAPDDLTSAAEHAQSQGHTPVWVAWDGAV
MAB_3984c|M.abscessus_ATCC_199      VVDGQEVSI-----------------------EAIEGQNTTAAVSWGGLR
Rv0103c|M.tuberculosis_H37Rv        EVGGHHVEVGKPSWITR-TTPCHDAALVSARLDGESRGETVVFVSVDGVV
Mb0106c|M.bovis_AF2122/97           EVGGHHVEVGKPSWITR-TTPCHDAALVSARLDGESRGETVVFVSVDGVV
MMAR_0269|M.marinum_M               IVDGHRIEVGKPSWITR-NT-AADEVLDTARAQGESRGETIVFVSVDGEV
MUL_4845|M.ulcerans_Agy99           IVDGHRIEVGKPSWITR-NT-AADEVLDTARAQGESRGETIVFVSVDGEV
MLBr_02000|M.leprae_Br4923          VVAEHHVKIGKPSWVTR-NA-PCDVVLESARREGESRGETVVFVSVDGVA
                                     *  : : :                        .    .* . *. .*  

Mflv_0912|M.gilvum_PYR-GCK          RGVLVVADTVKPTSAQAISQMRDLGLTPVLLTGDNEAVARQIAAEVGID-
MAV_5246|M.avium_104                RGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG-
MSMEG_5014|M.smegmatis_MC2_155      RGVLVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID-
TH_4361|M.thermoresistible__bu      AGVIVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID-
Mvan_3670|M.vanbaalenii_PYR-1       RGVIVVADTVKGTSADAIGQFRKLGLRPFLLTGDNRRAALAVAAEVGIDP
MAB_3984c|M.abscessus_ATCC_199      RGEIEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAA
Rv0103c|M.tuberculosis_H37Rv        RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID-
Mb0106c|M.bovis_AF2122/97           RAALTIADTLKDSAAAAVAALRSRGLRTILLTGDNRAAADAVAAQVGID-
MMAR_0269|M.marinum_M               CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAAADSVATQLGID-
MUL_4845|M.ulcerans_Agy99           CAAVTISDTVKDSAADAIAALRSRGLRTILLTGDNQAVADSVATQLGID-
MLBr_02000|M.leprae_Br4923          CGAVAIADTVKDSAADAISALCSRGLHTILLTGDNQAAARAVAAQVGID-
                                     . : ::*::*  :  *:  :   *  ..:*****  .*   * ::**  

Mflv_0912|M.gilvum_PYR-GCK          -TVIAEVMPKDKVDVIARLQSEGKTVAMVGDGVNDAPALAQADLGLAMGT
MAV_5246|M.avium_104                -EVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGT
MSMEG_5014|M.smegmatis_MC2_155      -DVYAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGT
TH_4361|M.thermoresistible__bu      -DVIAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGT
Mvan_3670|M.vanbaalenii_PYR-1       DDVIAEVLPADKVDTIKCLQAQGRTVAMVGDGVNDAAALVQADLGLAMGT
MAB_3984c|M.abscessus_ATCC_199      GDVIAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGT
Rv0103c|M.tuberculosis_H37Rv        -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR
Mb0106c|M.bovis_AF2122/97           -SAVADMLPEGKVDVIQRLREEGHTVAMVGDGINDGPALVGADLGLAIGR
MMAR_0269|M.marinum_M               -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR
MUL_4845|M.ulcerans_Agy99           -TAIADVLPDGKVNVIRQLRDQGHTVAMVGDGINDGPALVSADLGLAIGR
MLBr_02000|M.leprae_Br4923          -TVIADMLPEAKVDVIQRLRDQGHTVAMVGDGINDGPALACADLGLAMGR
                                      . :   *  *.: :  *:  *: ***:***:**..**. **:*:::* 

Mflv_0912|M.gilvum_PYR-GCK          GTDVAIEASDITLVRGDLRSAVDAIRLSRRTLSTIKTNLFWAFAYNVAAI
MAV_5246|M.avium_104                GTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAI
MSMEG_5014|M.smegmatis_MC2_155      GTDVAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAAL
TH_4361|M.thermoresistible__bu      GTDVAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAAL
Mvan_3670|M.vanbaalenii_PYR-1       GSDVAIEASDLTLVRGDLRAAADAIRLARSTLRTIKGNLFWAFAYNVAAL
MAB_3984c|M.abscessus_ATCC_199      GTDAAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAI
Rv0103c|M.tuberculosis_H37Rv        GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI
Mb0106c|M.bovis_AF2122/97           GTDVALGAADIILVRDDLNTVPQALDLARATMRTIRMNMIWAFGYNVAAI
MMAR_0269|M.marinum_M               GTDVAIGAADIILVRDDLHIVGQALDLARATLRTIRTNMIWAFGYNVAAI
MUL_4845|M.ulcerans_Agy99           GTDVAIGAADIILVRDDLHIVGQALDLARATMRTIRTNMIWAFGYNVAAI
MLBr_02000|M.leprae_Br4923          GTDVAIGAADLILVRDSLGVVPVALDLARATMRTIRINMIWAFGYNVAAI
                                    *:*.*: *.*: :* ..*  .  *: *.* *: **: *:.***.** **:

Mflv_0912|M.gilvum_PYR-GCK          PVAALGMLNPMLAGAAMAFSSVFVVGNSLRLRGFTSTSSAPTH-------
MAV_5246|M.avium_104                PLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA---------
MSMEG_5014|M.smegmatis_MC2_155      PLAAAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR---------------
TH_4361|M.thermoresistible__bu      PLAAAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR------------
Mvan_3670|M.vanbaalenii_PYR-1       PLAALGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTSSASPGQTEDVHVAT
MAB_3984c|M.abscessus_ATCC_199      PLAALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR---------------
Rv0103c|M.tuberculosis_H37Rv        PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ-------------
Mb0106c|M.bovis_AF2122/97           PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGAQ-------------
MMAR_0269|M.marinum_M               PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD
MUL_4845|M.ulcerans_Agy99           PIAAAGLLNPLIAGAAMAFSSFFVVSNSLRLRNFGPPTARIVASNGEIDD
MLBr_02000|M.leprae_Br4923          PIASSGLLNPLIAGAAMAFSSFFVVSNSLRLSNFGLSQTSD---------
                                    *:*: *:***::******:**.:** *****  *                

Mflv_0912|M.gilvum_PYR-GCK          ---------------
MAV_5246|M.avium_104                ---------------
MSMEG_5014|M.smegmatis_MC2_155      ---------------
TH_4361|M.thermoresistible__bu      ---------------
Mvan_3670|M.vanbaalenii_PYR-1       VPPGGDEYRRAHTAP
MAB_3984c|M.abscessus_ATCC_199      ---------------
Rv0103c|M.tuberculosis_H37Rv        ---------------
Mb0106c|M.bovis_AF2122/97           ---------------
MMAR_0269|M.marinum_M               ---------------
MUL_4845|M.ulcerans_Agy99           ---------------
MLBr_02000|M.leprae_Br4923          ---------------