For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. leprae Br4923 MLBr_01539 (-)

annotation: hypothetical protein MLBr_01539
coordinates: 1856445 - 1857956
length: 503

TAVADAPRTDIEGTSSPRVVVVGIVAGEGAQISVLLDANAPVSVMTDPLLKVINSRLCELGEGTLEPTGR
GRWALCLIDGTPLWPTQSLTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVSANLSKRFAAIDSIVAVQ
VGALMVATGVLASSVLLVWWRWHHGFWLSVIYATVIALLILVMSTLVLMRATTREDRRAGDIMLLSGIAP
VTAAAAAAPPGPLGSPHAVMGFGVFAIAAMLALRFTGRQLSIYTAMITISVVVAIASLARMVAMTSAVTL
LSCVMLACVLLYHCAPALSRRLAGIRLPVFPSATSRWVFEARPDLPNTVVRSDGGPPVLEGPASVRDVLL
QSERARSYLSGLLLGLGVLLVVSLTALSNPHVGQRWLPLLLAGFTSGFLLLRGRSYVDRWQAITLAATAV
LIVAAVVVRYALVLSSPLAVSIGAAILVLLPAAGLIAAAVVPNTIYSPLFRKLVEWIEYLCLVPIFPLAL
WLMDVYTAIRYR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01539--100% (503)hypothetical protein MLBr_01539
M. leprae Br4923MLBr_00047-5e-1623.71% (523) hypothetical protein MLBr_00047
M. leprae Br4923MLBr_02529-5e-1425.24% (416) hypothetical protein MLBr_02529

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1823-0.077.14% (503) hypothetical protein Mb1823
M. gilvum PYR-GCKMflv_0764-1e-1622.36% (492) hypothetical protein Mflv_0764
M. tuberculosis H37RvRv1795-0.076.94% (503) hypothetical protein Rv1795
M. abscessus ATCC 19977MAB_3757-8e-2625.94% (505) hypothetical protein MAB_3757
M. marinum MMMAR_2677-0.076.34% (503) hypothetical protein MMAR_2677
M. avium 104MAV_2919snm0.077.93% (503) secretion protein Snm4
M. smegmatis MC2 155MSMEG_0068-4e-1922.07% (521) transmembrane protein
M. thermoresistible (build 8)TH_2236-6e-1823.83% (533) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_3080-0.076.14% (503) hypothetical protein MUL_3080
M. vanbaalenii PYR-1Mvan_0081-2e-1923.45% (516) hypothetical protein Mvan_0081

CLUSTAL 2.0.9 multiple sequence alignment


Mb1823|M.bovis_AF2122/97            MTAVADAP--------QADIEGVASPQAVVVGVMAGEGVQIGVLLDANAP
Rv1795|M.tuberculosis_H37Rv         MTAVADAP--------QADIEGVASPQAVVVGVMAGEGVQIGVLLDANAP
MMAR_2677|M.marinum_M               MTAVADAP--------QAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAP
MUL_3080|M.ulcerans_Agy99           MTAVADAP--------QAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAP
MAV_2919|M.avium_104                MTAVVEVP--------QPDVEGISQPQAVVVGVMAGAGVQIGVLLDANAP
MLBr_01539|M.leprae_Br4923          MTAVADAP--------RTDIEGTSSPRVVVVGIVAGEGAQISVLLDANAP
Mflv_0764|M.gilvum_PYR-GCK          ------------------------------MTILTGR-RMTDLVLPSAAP
Mvan_0081|M.vanbaalenii_PYR-1       MTATVAP------PTSSN--VTPGRPTTTRVTILTGR-RMTDLVLPSAAP
MSMEG_0068|M.smegmatis_MC2_155      MTSTAAA-----ADTSS---VTPGRPSTTRVTILTGK-RMTDLVLPATAP
TH_2236|M.thermoresistible__bu      LTATASASAPGAAATASGTGATPARPATTRVTILTGR-RMTDLVLPAAAP
MAB_3757|M.abscessus_ATCC_1997      MTHAQSGAE-----------QRSAVLELCRVSIQAER-TQVDLALPTSVP
                                                                  : : :      .: * : .*

Mb1823|M.bovis_AF2122/97            VSVMTDPLLKVVNSRLRELG---EAPLEATGRGRWALCLVDGAPLRATQS
Rv1795|M.tuberculosis_H37Rv         VSVMTDPLLKVVNSRLRELG---EAPLEATGRGRWALCLVDGAPLRATQS
MMAR_2677|M.marinum_M               VSVMTDPLLKVVNSRLRELG---ESTLEAAGRGRWALCLIDGSPLRATQS
MUL_3080|M.ulcerans_Agy99           VSVMTDPLLKVVNSRLRELG---ESTLEAAGRGRWALCLIDGSPLRATQS
MAV_2919|M.avium_104                VSVMTEPLLKVVNSRLRELG---ETPLEATGRGRWALCLVDGSPLRATQS
MLBr_01539|M.leprae_Br4923          VSVMTDPLLKVINSRLCELG---EGTLEPTGRGRWALCLIDGTPLWPTQS
Mflv_0764|M.gilvum_PYR-GCK          IETYVDETVAVLGDILSDTPPDVLAGFDFTAQGVWSFARPGAPPIKLTDS
Mvan_0081|M.vanbaalenii_PYR-1       IETYVDETVSVLADILADTPENVLADFDFKAQGVWSFARPGAPPIKLTES
MSMEG_0068|M.smegmatis_MC2_155      IETYIDETVSFLAELLEDAPKDVLAGFNFGEQGVWAFARPGAPPLKADES
TH_2236|M.thermoresistible__bu      IESYIDETVSVLAELLEDTPSDVLAGFDFKAQGVWAFARPGAPPLKSDES
MAB_3757|M.abscessus_ATCC_1997      LALLVGSIVDIINQHVGVPE---LTSPEDAVETHWRLSRPGQPPLQMSST
                                    :       : .: . :           :   .  * :.  . .*:   .:

Mb1823|M.bovis_AF2122/97            LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVA
Rv1795|M.tuberculosis_H37Rv         LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVA
MMAR_2677|M.marinum_M               LTEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVASNLSKRFASIDPVVA
MUL_3080|M.ulcerans_Agy99           LTEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVASNLSKRFASIDPVVA
MAV_2919|M.avium_104                LSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLSKRFAAIDPVVA
MLBr_01539|M.leprae_Br4923          LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVSANLSKRFAAIDSIVA
Mflv_0764|M.gilvum_PYR-GCK          LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAV-LDETPEFDRRALY
Mvan_0081|M.vanbaalenii_PYR-1       LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAV-LDETPEFDRSALY
MSMEG_0068|M.smegmatis_MC2_155      LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAV-LDESPVFDRTALK
TH_2236|M.thermoresistible__bu      LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAV-LDESPEFDRSALN
MAB_3757|M.abscessus_ATCC_1997      LGELEVRDGD-LLILTRSDVAAPDPLFDDVFLAVSTFRTVSAHPWSRNAA
                                    * :  * **. * :   . .     :.:.:  *::               

Mb1823|M.bovis_AF2122/97            VQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVLVLAVAMLLL
Rv1795|M.tuberculosis_H37Rv         VQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVLVLAVAMLLL
MMAR_2677|M.marinum_M               VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MUL_3080|M.ulcerans_Agy99           VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MAV_2919|M.avium_104                VQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIGVLMLGVSVLLL
MLBr_01539|M.leprae_Br4923          VQVGALMVATGVLASSVLLVWWRWHHGFWLSVIYATVIALLILVMSTLVL
Mflv_0764|M.gilvum_PYR-GCK          RFVGLVLPLVALLTTVMAVLSWSSTGRDWWWAAALGVLGTGLLGGSALSQ
Mvan_0081|M.vanbaalenii_PYR-1       RFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGGSVLAQ
MSMEG_0068|M.smegmatis_MC2_155      HFVAIALPIVATIITVATLIAWTRSGHGWWWAVALGVLGLGLLGGSMAAK
TH_2236|M.thermoresistible__bu      RYIAVAIPIVSLIVTIVGLLSWANSGQSWWWALGLGLLGLGVLGGSMLAK
MAB_3757|M.abscessus_ATCC_1997      RILGASVCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTAAVFAN
                                      :.  :   .       :                  :.   :  :    

Mb1823|M.bovis_AF2122/97            MRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGS-PQAVLGFGVLTV
Rv1795|M.tuberculosis_H37Rv         MRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGS-PQAVLGFGVLTV
MMAR_2677|M.marinum_M               MRATTDADRRVADIMLVSGLAPLTVAAASAPPGSVGS-PQAVLGFGVLSI
MUL_3080|M.ulcerans_Agy99           MRATTDADRRVADIMLVSGLAPLTVAAASAPPGSVGS-PQAALGFGVLSI
MAV_2919|M.avium_104                MRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGS-PQAVLGFGVLTI
MLBr_01539|M.leprae_Br4923          MRATTREDRRAGDIMLLSGIAPVTAAAAAAPPGPLGS-PHAVMGFGVFAI
Mflv_0764|M.gilvum_PYR-GCK          RRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVAGAGALIL
Mvan_0081|M.vanbaalenii_PYR-1       NRYRHLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAGALVL
MSMEG_0068|M.smegmatis_MC2_155      SRYNSLDMSESLLLAATPALAGAVGLAVPLPRGVDGLGAPQLAGAAAVVL
TH_2236|M.thermoresistible__bu      SRYDNIDMTESLLVGSMPLLAGAAALAVPLPRGVTSLGAPQLAAVGAVIL
MAB_3757|M.abscessus_ATCC_1997      ---RVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGA-PHAMLALMVAMV
                                                       :      ..    *  .  .    .  .  :

Mb1823|M.bovis_AF2122/97            AAALALRFTGRRLGIYTAIVIIDALTMLAALARMVAATSAVTLLSSLLLI
Rv1795|M.tuberculosis_H37Rv         AAALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLI
MMAR_2677|M.marinum_M               AAALALRFTGRRLAIYTAIVTICGLTTLASLSRMVAATSAVTLFATMLLI
MUL_3080|M.ulcerans_Agy99           AAALALRFTGRRLAIYTAIVTICGLTTLASLSRMVAATSAVTLFATMLLI
MAV_2919|M.avium_104                AAVLALRFTGRRLAIYTAIVTVSAIAALAALARMVAMTGAVTLLTCVVLV
MLBr_01539|M.leprae_Br4923          AAMLALRFTGRQLSIYTAMITISVVVAIASLARMVAMTSAVTLLSCVMLA
Mflv_0764|M.gilvum_PYR-GCK          LMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVPAGAIAFG
Mvan_0081|M.vanbaalenii_PYR-1       LMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFGYGWNDWVPAGAIAFG
MSMEG_0068|M.smegmatis_MC2_155      LLTLATRGGPRKRAEVASFVAVTSIAVTAAAIAFGYGWQEWVPAGAIAFG
TH_2236|M.thermoresistible__bu      LITLASRGGPRRRAELASFIAVTALAVTAAAVAYGYGWEYWVPVGAIAFG
MAB_3757|M.abscessus_ATCC_1997      VSILAMRATGTGTTSLVAVASASFLGFAAALGYVLFEPPIYSLGAVLGSV
                                       ** *         .:.     :    :                :   

Mb1823|M.bovis_AF2122/97            CVVAYHAAPALSRRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAP
Rv1795|M.tuberculosis_H37Rv         CVVAYHAAPALSRRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAP
MMAR_2677|M.marinum_M               CVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAVAAGGPP
MUL_3080|M.ulcerans_Agy99           CVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAVAAGGPP
MAV_2919|M.avium_104                SVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPTTVVRSDGGPP
MLBr_01539|M.leprae_Br4923          CVLLYHCAPALSRRLAGIRLPVFPSATSRWVFEARPDLPNTVVRSDGGPP
Mflv_0764|M.gilvum_PYR-GCK          LIVVTNAA-KMTVAVARIALPPIPAPGESVTNDELLDPVATTDAS-EESE
Mvan_0081|M.vanbaalenii_PYR-1       LIVVTNAA-KLTVAVARIALPPIPAPGETVTNDELLDPVTTTDAS-EESE
MSMEG_0068|M.smegmatis_MC2_155      LIVVTNAA-KLTVAVARIALPPIPAPGEHVSNDELLDPVVTPDSIDDASP
TH_2236|M.thermoresistible__bu      LIVVTNAA-KLTVAVARIALPPIPAPGETVTNDDLLDPVITPDGSDEETS
MAB_3757|M.abscessus_ATCC_1997      GICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLDGLDT
                                     :     :  ::  :: : ** .*:       :       :         

Mb1823|M.bovis_AF2122/97            ------VLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCD--
Rv1795|M.tuberculosis_H37Rv         ------VLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCD--
MMAR_2677|M.marinum_M               ------VLEGPASVRDVVLQAERARSFLSGLLVGLGVLMVVSLTSLCN--
MUL_3080|M.ulcerans_Agy99           ------VLEGPASVRDVVLQAERARSFLSGLLVGLGVLMVVSLTSLCN--
MAV_2919|M.avium_104                ------VLEGPASVRDVLTQAERARSFLSGLLIGLGVLMVVSLTALSD--
MLBr_01539|M.leprae_Br4923          ------VLEGPASVRDVLLQSERARSYLSGLLLGLGVLLVVSLTALSN--
Mflv_0764|M.gilvum_PYR-GCK          TWQ-AIIASVPDSAARLTERSRLAKRLLIGFLS-AGALILVLGSVFVV--
Mvan_0081|M.vanbaalenii_PYR-1       TWQ-AIIASVPSSAARLTERSRLAKRLLIGFLS-AGALILAAGSIAVV--
MSMEG_0068|M.smegmatis_MC2_155      TWQ-AIIASVPESAARLQERSQLTRQLLIGFLS-AGALILTVGAIAVV--
TH_2236|M.thermoresistible__bu      TWQ-AIIASVPESAQRLQERSTLAKQLLIGFLT-AGAVVLSAGAIAVV--
MAB_3757|M.abscessus_ATCC_1997      EGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSAVTAVGAMLAALTF
                                                .   :  ::  ::  * *::   ..:            

Mb1823|M.bovis_AF2122/97            -------PHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTAVII
Rv1795|M.tuberculosis_H37Rv         -------PHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTAVII
MMAR_2677|M.marinum_M               -------PHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIV
MUL_3080|M.ulcerans_Agy99           -------PHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIV
MAV_2919|M.avium_104                -------PRTGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGTAVLI
MLBr_01539|M.leprae_Br4923          -------PHVGQRWLPLLLAGFTSGFLLLRGRSYVDRWQAITLAATAVLI
Mflv_0764|M.gilvum_PYR-GCK          -------VQGHFFVHSMIVAGLVTMLAGFRSRLYVERWCAWALMAAAVAI
Mvan_0081|M.vanbaalenii_PYR-1       -------VQGHFFLHSMIVAGLVTMLCGFRSRLYAERWCAWALMAAAVAV
MSMEG_0068|M.smegmatis_MC2_155      -------VQGHFFVHSMIVASLVTVICGFRSRLYAERWCAWALLAATVAV
TH_2236|M.thermoresistible__bu      -------VQGHFFVHSLIVAGLVTMICAFRSRLYAERWCAWALLAACTAI
MAB_3757|M.abscessus_ATCC_1997      SGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQTVAINLGGIAI
                                                    :::*.: :    :*.* :.:   : ::      :

Mb1823|M.bovis_AF2122/97            AAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRK
Rv1795|M.tuberculosis_H37Rv         AAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRK
MMAR_2677|M.marinum_M               VAAVSVRYALVLSSPLSVSIVASLLVLLPAAGMTAAAVVPNTIYSPLFRK
MUL_3080|M.ulcerans_Agy99           VAAVSVRYALVLSSPLSVSIVASLLVLLPAAGMTAAAVVPNTIYSPLFRK
MAV_2919|M.avium_104                VGAVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVYSPLFRK
MLBr_01539|M.leprae_Br4923          VAAVVVRYALVLSSPLAVSIGAAILVLLPAAGLIAAAVVPNTIYSPLFRK
Mflv_0764|M.gilvum_PYR-GCK          PSGIAVRMSLWYP-DRAWWVLGIYTVAAAVALIVVGATDGVRRISPVTKR
Mvan_0081|M.vanbaalenii_PYR-1       PTGVVVRLCLWYP-ERAWLLLAIYTALALLAVIVIGASEGVRRISPVTKR
MSMEG_0068|M.smegmatis_MC2_155      PTGLMIKLSMWWP-DSAWIVMGIYTMLALIALIVVGATDGVRRVSPVTKR
TH_2236|M.thermoresistible__bu      PTGVMVKLCMWYP-ERAAVVLGIYVAAVLVAVIAVGATHGVRRMSPVTKR
MAB_3757|M.abscessus_ATCC_1997      PAAAFAFVAVAYP--TAAVFTTVLAAIAAGSAIALGFLVSARKYSPVARR
                                      .     .:      :  .          : :  .        **: ::

Mb1823|M.bovis_AF2122/97            FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
Rv1795|M.tuberculosis_H37Rv         FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
MMAR_2677|M.marinum_M               FVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MUL_3080|M.ulcerans_Agy99           FVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MAV_2919|M.avium_104                FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
MLBr_01539|M.leprae_Br4923          LVEWIEYLCLVPIFPLALWLMDVYTAIRYR---
Mflv_0764|M.gilvum_PYR-GCK          ILELLDGATIAAVIPLLLWISGVYDVLRNLRF-
Mvan_0081|M.vanbaalenii_PYR-1       ILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
MSMEG_0068|M.smegmatis_MC2_155      ILELFDGAAIAAVIPLLLWIAGVYDLLRNLRLH
TH_2236|M.thermoresistible__bu      ILELVDGAAIAATIPMLLWIGSVFDILRNIRF-
MAB_3757|M.abscessus_ATCC_1997      TVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
                                     :*  :   :   .*: .*: .*:  :*