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TILTGRRMTDLVLPSAAPIETYVDETVAVLGDILSDTPPDVLAGFDFTAQGVWSFARPGAPPIKLTDSLD DAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDETPEFDRRALYRFVGLVLPLVALLTTVMAVLSWS STGRDWWWAAALGVLGTGLLGGSALSQRRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVA GAGALILLMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVPAGAIAFGLIVVTNAAKMTVA VARIALPPIPAPGESVTNDELLDPVATTDASEESETWQAIIASVPDSAARLTERSRLAKRLLIGFLSAGA LILVLGSVFVVVQGHFFVHSMIVAGLVTMLAGFRSRLYVERWCAWALMAAAVAIPSGIAVRMSLWYPDRA WWVLGIYTVAAAVALIVVGATDGVRRISPVTKRILELLDGATIAAVIPLLLWISGVYDVLRNLRF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0764 | - | - | 100% (486) | hypothetical protein Mflv_0764 |
| M. gilvum PYR-GCK | Mflv_0321 | - | 3e-23 | 25.35% (505) | hypothetical protein Mflv_0321 |
| M. gilvum PYR-GCK | Mflv_4960 | - | 8e-14 | 23.96% (480) | hypothetical protein Mflv_4960 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3907 | - | 0.0 | 66.12% (487) | transmembrane protein |
| M. tuberculosis H37Rv | Rv3877 | - | 0.0 | 66.12% (487) | transmembrane protein |
| M. leprae Br4923 | MLBr_00047 | - | 1e-180 | 62.50% (488) | hypothetical protein MLBr_00047 |
| M. abscessus ATCC 19977 | MAB_3757 | - | 3e-26 | 22.64% (508) | hypothetical protein MAB_3757 |
| M. marinum M | MMAR_5452 | - | 0.0 | 64.09% (479) | hypothetical protein MMAR_5452 |
| M. avium 104 | MAV_2919 | snm | 6e-21 | 24.65% (499) | secretion protein Snm4 |
| M. smegmatis MC2 155 | MSMEG_0068 | - | 0.0 | 72.63% (486) | transmembrane protein |
| M. thermoresistible (build 8) | TH_2236 | - | 0.0 | 72.48% (487) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1212 | - | 1e-21 | 26.85% (499) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0081 | - | 0.0 | 86.01% (486) | hypothetical protein Mvan_0081 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3907|M.bovis_AF2122/97 MSAPAVA------AGPTAAGATAARPATTRVTILTGR-RMTDLVLPAAVP
Rv3877|M.tuberculosis_H37Rv MSAPAVA------AGPTAAGATAARPATTRVTILTGR-RMTDLVLPAAVP
MMAR_5452|M.marinum_M ---------------------------------------MTDLVLPAAAP
MLBr_00047|M.leprae_Br4923 MSAPAVT------AGPATAGITPARPSATRVTILTGK-RMTDLVLPSTVS
Mflv_0764|M.gilvum_PYR-GCK ------------------------------MTILTGR-RMTDLVLPSAAP
Mvan_0081|M.vanbaalenii_PYR-1 MTATVAP------PTSSN--VTPGRPTTTRVTILTGR-RMTDLVLPSAAP
MSMEG_0068|M.smegmatis_MC2_155 MTSTAAA-----ADTSS---VTPGRPSTTRVTILTGK-RMTDLVLPATAP
TH_2236|M.thermoresistible__bu LTATASASAPGAAATASGTGATPARPATTRVTILTGR-RMTDLVLPAAAP
MUL_1212|M.ulcerans_Agy99 --------------------MSGTVMPIVRVAILADS-RLTEVALPAELP
MAB_3757|M.abscessus_ATCC_1997 -----------MTHAQSGAEQRSAVLELCRVSIQAER-TQVDLALPTSVP
MAV_2919|M.avium_104 --------MTAVVEVPQPDVEGISQPQAVVVGVMAGAGVQIGVLLDANAP
: * : .
Mb3907|M.bovis_AF2122/97 METYIDDTVAVLSEVLEDTPADVLGGFDFTAQGVWAFARPGSPPLKLDQS
Rv3877|M.tuberculosis_H37Rv METYIDDTVAVLSEVLEDTPADVLGGFDFTAQGVWAFARPGSPPLKLDQS
MMAR_5452|M.marinum_M MESYVDETVAILADLLEDTPAEVLAGFDFEAQGVWTFARPGFPPLKLDQS
MLBr_00047|M.leprae_Br4923 IEAYIDETVAVLSDLLEDAPADVLAGFDFSAQGVWTFARPGSPPMKLDQS
Mflv_0764|M.gilvum_PYR-GCK IETYVDETVAVLGDILSDTPPDVLAGFDFTAQGVWSFARPGAPPIKLTDS
Mvan_0081|M.vanbaalenii_PYR-1 IETYVDETVSVLADILADTPENVLADFDFKAQGVWSFARPGAPPIKLTES
MSMEG_0068|M.smegmatis_MC2_155 IETYIDETVSFLAELLEDAPKDVLAGFNFGEQGVWAFARPGAPPLKADES
TH_2236|M.thermoresistible__bu IESYIDETVSVLAELLEDTPSDVLAGFDFKAQGVWAFARPGAPPLKSDES
MUL_1212|M.ulcerans_Agy99 LREILPAVQRLVIPVAEDG---DAGSADLGIAGHLSLAPVGGAPFSLDAS
MAB_3757|M.abscessus_ATCC_1997 LALLVGSIVDIINQHVGVP---ELTSPEDAVETHWRLSRPGQPPLQMSST
MAV_2919|M.avium_104 VSVMTEPLLKVVNSRLRELG---ETPLEATGRGRWALCLVDGSPLRATQS
: .: : :. . .*: :
Mb3907|M.bovis_AF2122/97 LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRTAL
Rv3877|M.tuberculosis_H37Rv LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRTAL
MMAR_5452|M.marinum_M LDEAGVVDGSLLTLVLASRTERYRPLVEDVIDAIAVLDES--PEFNRTAL
MLBr_00047|M.leprae_Br4923 LDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNES--PEFNRKAV
Mflv_0764|M.gilvum_PYR-GCK LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDRRAL
Mvan_0081|M.vanbaalenii_PYR-1 LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDRSAL
MSMEG_0068|M.smegmatis_MC2_155 LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PVFDRTAL
TH_2236|M.thermoresistible__bu LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRSAL
MUL_1212|M.ulcerans_Agy99 LDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRLRPWDARHL
MAB_3757|M.abscessus_ATCC_1997 LGELEVRDGDLLILTRS-DVAAPDPLFDDVFLAVSTFRTVSAHPWSR-NA
MAV_2919|M.avium_104 LSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLSKRFAAIDP-VV
*. * **. * : :.:.: * .
Mb3907|M.bovis_AF2122/97 NRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVG---S
Rv3877|M.tuberculosis_H37Rv NRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVG---S
MMAR_5452|M.marinum_M ERFLAVAIPLFALPITAVAMRAWWQTGRSVFWPLAIGLIGLAALAG---S
MLBr_00047|M.leprae_Br4923 DRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTG---S
Mflv_0764|M.gilvum_PYR-GCK YRFVGLVLPLVALLTTVMAVLSWSSTGRDWWWAAALGVLGTGLLGG---S
Mvan_0081|M.vanbaalenii_PYR-1 YRFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGG---S
MSMEG_0068|M.smegmatis_MC2_155 KHFVAIALPIVATIITVATLIAWTRSGHGWWWAVALGVLGLGLLGG---S
TH_2236|M.thermoresistible__bu NRYIAVAIPIVSLIVTIVGLLSWANSGQSWWWALGLGLLGLGVLGG---S
MUL_1212|M.ulcerans_Agy99 QRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAMALAG---L
MAB_3757|M.abscessus_ATCC_1997 ARILGASVCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTA---A
MAV_2919|M.avium_104 AVQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIGVLMLGVSVLL
: : :
Mb3907|M.bovis_AF2122/97 FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
Rv3877|M.tuberculosis_H37Rv FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
MMAR_5452|M.marinum_M FVAKRFYQNSRLAESLLVTSYGVIAAAAAIAVPLPRGFHSLGAPQLAAAA
MLBr_00047|M.leprae_Br4923 IVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDSLGPPQVAAAA
Mflv_0764|M.gilvum_PYR-GCK ALSQRRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVAGAG
Mvan_0081|M.vanbaalenii_PYR-1 VLAQNRYRHLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAG
MSMEG_0068|M.smegmatis_MC2_155 MAAKSRYNSLDMSESLLLAATPALAGAVGLAVPLPRGVDGLGAPQLAGAA
TH_2236|M.thermoresistible__bu MLAKSRYDNIDMTESLLVGSMPLLAGAAALAVPLPRGVTSLGAPQLAAVG
MUL_1212|M.ulcerans_Agy99 LLGAR---SPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGVTA
MAB_3757|M.abscessus_ATCC_1997 VFANRVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGAPHAMLALMVAMV
MAV_2919|M.avium_104 LMRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGSPQAVLGFGVLTI
* : * * *
Mb3907|M.bovis_AF2122/97 TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
Rv3877|M.tuberculosis_H37Rv TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
MMAR_5452|M.marinum_M TAVLFITLMMRGGPYKRHDIAAFVVITSIAVISAAVAFGYGYQQWVP-AG
MLBr_00047|M.leprae_Br4923 AAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQHWVP-TG
Mflv_0764|M.gilvum_PYR-GCK ALILLMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVP-AG
Mvan_0081|M.vanbaalenii_PYR-1 ALVLLMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFGYGWNDWVP-AG
MSMEG_0068|M.smegmatis_MC2_155 AVVLLLTLATRGGPRKRAEVASFVAVTSIAVTAAAIAFGYGWQEWVP-AG
TH_2236|M.thermoresistible__bu AVILLITLASRGGPRRRAELASFIAVTALAVTAAAVAYGYGWEYWVP-VG
MUL_1212|M.ulcerans_Agy99 WSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGVELLWQLPVSSIGCG
MAB_3757|M.abscessus_ATCC_1997 VSILAMRATGTG----TTSLVAVASASFLGFAAALGYVLFEPPIYSLGAV
MAV_2919|M.avium_104 AAVLALRFTGRR----LAIYTAIVTVSAIAALAALARMVAMTGAVTLLTC
:: : .:.
Mb3907|M.bovis_AF2122/97 GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
Rv3877|M.tuberculosis_H37Rv GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
MMAR_5452|M.marinum_M AIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPITAQ-DAT
MLBr_00047|M.leprae_Br4923 AVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEAT
Mflv_0764|M.gilvum_PYR-GCK AIAFGLIVVTNAAKMTVAVARIALPPIPAPGESVTNDELLDPVATT-DAS
Mvan_0081|M.vanbaalenii_PYR-1 AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDELLDPVTTT-DAS
MSMEG_0068|M.smegmatis_MC2_155 AIAFGLIVVTNAAKLTVAVARIALPPIPAPGEHVSNDELLDPVVTP-DSI
TH_2236|M.thermoresistible__bu AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDDLLDPVITP-DGS
MUL_1212|M.ulcerans_Agy99 LIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPS--------------
MAB_3757|M.abscessus_ATCC_1997 LGSVGICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLD
MAV_2919|M.avium_104 VVLVSVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPTTVVRSD
.: :. :: * : ** .*
Mb3907|M.bovis_AF2122/97 SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
Rv3877|M.tuberculosis_H37Rv SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
MMAR_5452|M.marinum_M NEETPTWQAIIASAPASAARLTERSKLAKQLLVGYVTAGTLILAVGSIAV
MLBr_00047|M.leprae_Br4923 HEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAV
Mflv_0764|M.gilvum_PYR-GCK EE-SETWQAIIASVPDSAARLTERSRLAKRLLIGFLSAGALILVLGSVFV
Mvan_0081|M.vanbaalenii_PYR-1 EE-SETWQAIIASVPSSAARLTERSRLAKRLLIGFLSAGALILAAGSIAV
MSMEG_0068|M.smegmatis_MC2_155 DDASPTWQAIIASVPESAARLQERSQLTRQLLIGFLSAGALILTVGAIAV
TH_2236|M.thermoresistible__bu DEETSTWQAIIASVPESAQRLQERSTLAKQLLIGFLTAGAVVLSAGAIAV
MUL_1212|M.ulcerans_Agy99 -----------APSLRVLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAI
MAB_3757|M.abscessus_ATCC_1997 GLDTEGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSAVTAVGAMLA
MAV_2919|M.avium_104 GG------PPVLEGPASVRDVLTQAERARSFLSGLLIGLGVLMVVSLTAL
: : : * : . : .
Mb3907|M.bovis_AF2122/97 VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
Rv3877|M.tuberculosis_H37Rv VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
MMAR_5452|M.marinum_M VVHG---------HFFIHS-MIVAGLITVICSFRSRLYADPWCAWALLAA
MLBr_00047|M.leprae_Br4923 IVRG---------HFFAHS-LVVAFLLTVVCTFRSRLYAERWCAWALLAA
Mflv_0764|M.gilvum_PYR-GCK VVQG---------HFFVHS-MIVAGLVTMLAGFRSRLYVERWCAWALMAA
Mvan_0081|M.vanbaalenii_PYR-1 VVQG---------HFFLHS-MIVAGLVTMLCGFRSRLYAERWCAWALMAA
MSMEG_0068|M.smegmatis_MC2_155 VVQG---------HFFVHS-MIVASLVTVICGFRSRLYAERWCAWALLAA
TH_2236|M.thermoresistible__bu VVQG---------HFFVHS-LIVAGLVTMICAFRSRLYAERWCAWALLAA
MUL_1212|M.ulcerans_Agy99 ALRP---------DTVSALGWYVVAATAATATLRARIWDSAACKAWLLTQ
MAB_3757|M.abscessus_ATCC_1997 ALTFSGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQTVAINLG
MAV_2919|M.avium_104 SDPR---------TGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGT
:. : :*.* . :
Mb3907|M.bovis_AF2122/97 TVAIP---TGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVRRV
Rv3877|M.tuberculosis_H37Rv TVAIP---TGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVRRV
MMAR_5452|M.marinum_M TVAIP---TGLAVKLSLWYPHYAWLLLTIYLAAALVTLISVGAMNQVRRV
MLBr_00047|M.leprae_Br4923 AVVIP---TGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVRRV
Mflv_0764|M.gilvum_PYR-GCK AVAIP---SGIAVRMSLWYPDRAWWVLGIYTVAAAVALIVVGATDGVRRI
Mvan_0081|M.vanbaalenii_PYR-1 AVAVP---TGVVVRLCLWYPERAWLLLAIYTALALLAVIVIGASEGVRRI
MSMEG_0068|M.smegmatis_MC2_155 TVAVP---TGLMIKLSMWWPDSAWIVMGIYTMLALIALIVVGATDGVRRV
TH_2236|M.thermoresistible__bu CTAIP---TGVMVKLCMWYPERAAVVLGIYVAAVLVAVIAVGATHGVRRM
MUL_1212|M.ulcerans_Agy99 PYLVGGTLLVLYAATGHFIAAFGALVVLAVLAVAWVVVALNPVIASPESY
MAB_3757|M.abscessus_ATCC_1997 GIAIP---AAAFAFVAVAYPT-AAVFTTVLAAIAAGSAIALGFLVSARKY
MAV_2919|M.avium_104 AVLIVG--AVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVY
: . . . .
Mb3907|M.bovis_AF2122/97 SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
Rv3877|M.tuberculosis_H37Rv SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
MMAR_5452|M.marinum_M SPVMKRALELFDGAMVASIVPLLLWITGVYDLVRNIRF-
MLBr_00047|M.leprae_Br4923 SPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF-
Mflv_0764|M.gilvum_PYR-GCK SPVTKRILELLDGATIAAVIPLLLWISGVYDVLRNLRF-
Mvan_0081|M.vanbaalenii_PYR-1 SPVTKRILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
MSMEG_0068|M.smegmatis_MC2_155 SPVTKRILELFDGAAIAAVIPLLLWIAGVYDLLRNLRLH
TH_2236|M.thermoresistible__bu SPVTKRILELVDGAAIAATIPMLLWIGSVFDILRNIRF-
MUL_1212|M.ulcerans_Agy99 SLPLRRLLGFLAAGLDASLIPVMAYLAGLFTWVLNR---
MAB_3757|M.abscessus_ATCC_1997 SPVARRTVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
MAV_2919|M.avium_104 SPLFRKFVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
* :: : . .*: :: .:: :