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MTHAQSGAEQRSAVLELCRVSIQAERTQVDLALPTSVPLALLVGSIVDIINQHVGVPELTSPEDAVETHW RLSRPGQPPLQMSSTLGELEVRDGDLLILTRSDVAAPDPLFDDVFLAVSTFRTVSAHPWSRNAARILGAS VCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTAAVFANRVYDDSLASVMLSHCAVGFSAVAGAL FVPGKYGAPHAMLALMVAMVVSILAMRATGTGTTSLVAVASASFLGFAAALGYVLFEPPIYSLGAVLGSV GICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLDGLDTEGDDVEDATALPPLPDLREK ALRAHAVLTGLVCGTSAVTAVGAMLAALTFSGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQT VAINLGGIAIPAAAFAFVAVAYPTAAVFTTVLAAIAAGSAIALGFLVSARKYSPVARRTVEIIEYIALSL IVPIAVWVCGVYSAVRGLNLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3757 | - | - | 100% (511) | hypothetical protein MAB_3757 |
| M. abscessus ATCC 19977 | MAB_2226c | - | 2e-19 | 24.45% (503) | hypothetical protein MAB_2226c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3478 | - | 1e-57 | 33.86% (502) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4960 | - | 3e-42 | 30.77% (507) | hypothetical protein Mflv_4960 |
| M. tuberculosis H37Rv | Rv3448 | - | 6e-58 | 34.06% (502) | integral membrane protein |
| M. leprae Br4923 | MLBr_00047 | - | 4e-30 | 24.11% (506) | hypothetical protein MLBr_00047 |
| M. marinum M | MMAR_1101 | - | 1e-50 | 31.94% (501) | hypothetical protein MMAR_1101 |
| M. avium 104 | MAV_4391 | - | 1e-44 | 28.60% (500) | hypothetical protein MAV_4391 |
| M. smegmatis MC2 155 | MSMEG_1535 | - | 2e-37 | 29.80% (500) | hypothetical protein MSMEG_1535 |
| M. thermoresistible (build 8) | TH_3996 | - | 4e-41 | 30.55% (491) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0859 | - | 8e-50 | 31.54% (501) | hypothetical protein MUL_0859 |
| M. vanbaalenii PYR-1 | Mvan_1446 | - | 4e-30 | 28.11% (498) | hypothetical protein Mvan_1446 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3478|M.bovis_AF2122/97 --------------------MPTSDPGLRRVTVHAGA------------Q
Rv3448|M.tuberculosis_H37Rv --------------------MPTSDPGLRRVTVHAGA------------Q
MMAR_1101|M.marinum_M -------------------MLSGSEPGLCRVAVHSGT------------A
MUL_0859|M.ulcerans_Agy99 -------------------MLSGSEPGLCRVAVHSGT------------A
MAV_4391|M.avium_104 ------------------MALAVSTTGLCRVSVHWET------------Q
Mflv_4960|M.gilvum_PYR-GCK -----------------------MPDTLCRLTVHVVG--------ADESA
Mvan_1446|M.vanbaalenii_PYR-1 MPFHPQPGKVLQRRPPGPSYVDFVPDTLRRVAVHALG--------PREAA
MSMEG_1535|M.smegmatis_MC2_155 ----------------------MMPESLYRVSIHCA-------AADHAG-
TH_3996|M.thermoresistible__bu -----------------------VSDSVRRVSVQIDTLVDMLIGTDRGGT
MAB_3757|M.abscessus_ATCC_1997 -----------MTHAQSGAEQRSAVLELCRVSIQAER------------T
MLBr_00047|M.leprae_Br4923 ------MSAPAVTAGPATAGITPARPSATRVTILTGK------------R
*:::
Mb3478|M.bovis_AF2122/97 AVDLTLPAAVPVATLIPSIVDILGDRGASP----------ATAARYQLSA
Rv3448|M.tuberculosis_H37Rv AVDLTLPAAVPVATLIPSIVDILGDRGASP----------ATAARYQLSA
MMAR_1101|M.marinum_M VVDLSLPAALPVAELIPAIVESLGGRDIG-----------AAPTRYQLCP
MUL_0859|M.ulcerans_Agy99 VVDLSLPAALPFAELIPAIVESLGGRDIG-----------AAPTRYQLCP
MAV_4391|M.avium_104 AVDVSLPAEIAVAELIPSLVDMLGAGDGG-------------AGRYRLSA
Mflv_4960|M.gilvum_PYR-GCK AVDLVLPAACPLGELMPSLVDTIFGDT-------------AGQEHWQLTR
Mvan_1446|M.vanbaalenii_PYR-1 AADLVLPAEQPLAELVPSIVDTVFGGP-------------VGPRQWQLAT
MSMEG_1535|M.smegmatis_MC2_155 AADLVLPAAMTVSQLLPSIVAAVGAPG-------------DLPRRWYLAP
TH_3996|M.thermoresistible__bu VIDVTLPSGVEVAELIPAIVDLAVGADGVDA---------ESPTAWKLAR
MAB_3757|M.abscessus_ATCC_1997 QVDLALPTSVPLALLVGSIVDIINQHVGVPELTSPE---DAVETHWRLSR
MLBr_00047|M.leprae_Br4923 MTDLVLPSTVSIEAYIDETVAVLSDLLEDAPADVLAGFDFSAQGVWTFAR
*: **: . : * : :
Mb3478|M.bovis_AF2122/97 LGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDT
Rv3448|M.tuberculosis_H37Rv LGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDT
MMAR_1101|M.marinum_M LGAGALPPSQSLAQSGIRDGTVLSLSRCSAEPAPGPHDDDAEAVLATLRG
MUL_0859|M.ulcerans_Agy99 LGAGALPPSKSLAQRGIRDGTVLSLSRCSAEPAPGPHDDDAEAVLATLRG
MAV_4391|M.avium_104 PGAAALDPSTTLAHNHIGDGAILVLSRIDVPLPAPRYRDIADTVSAALDA
Mflv_4960|M.gilvum_PYR-GCK VTGPPLNPALSLRDNDIGDGDMVMLTASRVPSPRISPTEACTVVALAGGN
Mvan_1446|M.vanbaalenii_PYR-1 PAGVPLDSSMSLRDNVVEDGDVIVLTTARVPPPRLLPTDPCAVVADAAEK
MSMEG_1535|M.smegmatis_MC2_155 PGGAPLDESMTLAQNEVHDGAVLVLTARLPVAPRSYGLIHALTAAAPTPT
TH_3996|M.thermoresistible__bu VGGTVLDASRTLTENGIREGELLMLTG---AASAPVTRAEAPPGLEPAAG
MAB_3757|M.abscessus_ATCC_1997 PGQPPLQMSSTLGELEVRDGDLLILTRSDVAAPDPLFDDVFLAVSTFRTV
MLBr_00047|M.leprae_Br4923 PGSPPMKLDQSLDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNE
: :* . : :* :: *
Mb3478|M.bovis_AF2122/97 TARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVA
Rv3448|M.tuberculosis_H37Rv TARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVA
MMAR_1101|M.marinum_M STRPPSRRAKELTGALTAGGVGGVGAVLLVRDALG-NTDRHGAATAVVAI
MUL_0859|M.ulcerans_Agy99 STRPPSRRAKELTGALTAGGVGGVGAVLLVRDALG-NTDRHGAATAVVAI
MAV_4391|M.avium_104 TARP-DVAVRRVAGAAAAASFVAAGGLQLVRNTFSASVVPDSGGTVAVLV
Mflv_4960|M.gilvum_PYR-GCK RESGHGATPWC-IAGIIVAAVTLVR------------SGMVTPGGWHLWC
Mvan_1446|M.vanbaalenii_PYR-1 GTPGRGVNRAAGAAGIVACAVALVW------------SGTAAPTHWHLWC
MSMEG_1535|M.smegmatis_MC2_155 PPPASRMFAGLWTCAVGMAAVLCAG------------IGTGGPTRVIVAA
TH_3996|M.thermoresistible__bu RWHGARTALALWCPIAGTAAVVWTG------------LMRDDIGRTVPAA
MAB_3757|M.abscessus_ATCC_1997 SAHPWSRNAARILGASVCGLSALLGATALLRAG----ATNPGLLLPIIAV
MLBr_00047|M.leprae_Br4923 SPEFNRKAVDRFIGVAIPVLSLPITAVAVWAWW----VTGRSPFWSLAIG
Mb3478|M.bovis_AF2122/97 AAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHS
Rv3448|M.tuberculosis_H37Rv AAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHS
MMAR_1101|M.marinum_M TSGVLALLVAGMARRTGREPTAVFTLNVIATTFVAVGALLAVPGRLGVPN
MUL_0859|M.ulcerans_Agy99 TSRVLALLVAGMTRRTGREPTAVFTLNVIATTFVAVGALLAVPGRLGVPN
MAV_4391|M.avium_104 STTLLTLGAAAVAHRGYRDPGAALALGAIATVFAGLAGFVAVPGAPSLSH
Mflv_4960|M.gilvum_PYR-GCK AAALSGIAGTMSVALGRADRRVSTVLNTAAVVFAAATGVLAVPAAAWPAA
Mvan_1446|M.vanbaalenii_PYR-1 AAALSGSAAVGAVAAARAEPELTALLSTAAVVFATAAGLLAVRSAPWPAT
MSMEG_1535|M.smegmatis_MC2_155 VVAVAVTAVAFASRRLALTAAAATSVQSLAVASVAILGFVAVPSDSGPGN
TH_3996|M.thermoresistible__bu MLTVGAVAAVLPYR-HRRDPLTATASALIVVMLAAVLGLLVVPDGPGPPN
MAB_3757|M.abscessus_ATCC_1997 AIALVAMTAAVFANRVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGAPH
MLBr_00047|M.leprae_Br4923 ILSIVALTGSIVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDS
: . : .
Mb3478|M.bovis_AF2122/97 VLVAAMAAAATSVLAMR-ITGCGGITLTAVACCAVVVAAATLVGAITAAP
Rv3448|M.tuberculosis_H37Rv VLVAAMAAAATSVLAMR-ITGCGGITLTAVACCAVVVAAATLVGAITAAP
MMAR_1101|M.marinum_M LMLAAMGASVAAALAIR-LTGCGGVTFTAVMCCAIVIAAAALCGVITGAA
MUL_0859|M.ulcerans_Agy99 LMLAAMGASVAAALAIR-LTGCGGVTFTAVMCCAIVIAAAALCGVITGAA
MAV_4391|M.avium_104 VLLAAAAAGLAAVSAIG-LSGCG-AGLLALACWCLILATAALAGVLSGAP
Mflv_4960|M.gilvum_PYR-GCK TLLAAASALAMSTLLAR-MCPG-AADLPAFCAVAGAVTAAAALSHLAAPR
Mvan_1446|M.vanbaalenii_PYR-1 VLLASSAGFCMSVLLLR-LVAD-RALLTAFTAAGGAATAAAGLANLAAS-
MSMEG_1535|M.smegmatis_MC2_155 VFLAATAAASLGVVLLR-LTDGSVETMHAVVAFAVIAGIGAAVATLFPLD
TH_3996|M.thermoresistible__bu LMLAAAAAAAAAMVMAR-LTGVDIVGLTAVATGAAAVAISLIPAVLWPVP
MAB_3757|M.abscessus_ATCC_1997 AMLALMVAMVVSILAMR-ATGTGTTSLVAVASASFLGFAAALGYVLFEPP
MLBr_00047|M.leprae_Br4923 LGPPQVAAAAAAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGF
. . . . . :
Mb3478|M.bovis_AF2122/97 VPAIGSLDTLASFGLLEVS--ARMAVLLAGLSPRLPPALNPDDAD-----
Rv3448|M.tuberculosis_H37Rv VPAIGSLATLASFGLLEVS--ARMAVLLAGLSPRLPPALNPDDAD-----
MMAR_1101|M.marinum_M LYVVGSLTTLAALVALEVS--ARVSMVVAGLSPKLPAAPGSEEAP-----
MUL_0859|M.ulcerans_Agy99 LYVVGSLTTLAALVALEVS--ARVSMVVAGLSPKLPAAPGSEEAP-----
MAV_4391|M.avium_104 LPAVASAAGLVSLCLLGMA--ARASLALAGLSPRPATAPAGGPE------
Mflv_4960|M.gilvum_PYR-GCK LTTAGAVLVVLSLAGLAIS--PRITIALARLSPSRPAVDDE---------
Mvan_1446|M.vanbaalenii_PYR-1 PVTAGAALAALSTAALSVA--PKLAVVTAGPEP-----------------
MSMEG_1535|M.smegmatis_MC2_155 IQAFGACLGALGIAALSLS--PRMSIILAGLTPG-EASPAG---------
TH_3996|M.thermoresistible__bu TVVIGVLTASLSMAVLAVA--PRLSIALAGLTPAPDGGPDAPGS------
MAB_3757|M.abscessus_ATCC_1997 IYSLGAVLGSVGICAVALS--PRVAMVLARLPLPPVPTQGAPSRPEHSTA
MLBr_00047|M.leprae_Br4923 GYQHWVPTGAVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEE---
. . :: .: :: *
Mb3478|M.bovis_AF2122/97 ----------------------ALPTTDRLTTRANRADAWLTSLLAAFAA
Rv3448|M.tuberculosis_H37Rv ----------------------ALPTTDRLTTRANRADAWLTSLLAAFAA
MMAR_1101|M.marinum_M ----------------------ELAAPDLLATRAVRADRWLNGLHGGFSS
MUL_0859|M.ulcerans_Agy99 ----------------------ELAAPDLLATRAIRADRWLNGLHGGFSS
MAV_4391|M.avium_104 ------------------------PGEAWVSARARRADRWLTGLLAGLSS
Mflv_4960|M.gilvum_PYR-GCK --------------------------------EAAAAHTLLTALVAGWSS
Mvan_1446|M.vanbaalenii_PYR-1 ----------------------------------AAAHSTLTGLVAGWSA
MSMEG_1535|M.smegmatis_MC2_155 ----------------------------DVDVVAARGHRILCGLVAGASA
TH_3996|M.thermoresistible__bu -----------------------LFDDAPAAPRLVRGNAILTGILTGAAV
MAB_3757|M.abscessus_ATCC_1997 PIEAIEGLDGLDTEGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSA
MLBr_00047|M.leprae_Br4923 -LLDPVVTPHEATHEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVI
: .
Mb3478|M.bovis_AF2122/97 SATIGAIGTAVATHG-----------IHRSSMGGIALAAVTGALLLLRAR
Rv3448|M.tuberculosis_H37Rv SATIGAIGTAVATHG-----------IHRSSMGGIALAAVTGALLLLRAR
MMAR_1101|M.marinum_M AAALGAV---VAVLG-----------SQR----AIGLTAVTGAVLLLRAR
MUL_0859|M.ulcerans_Agy99 AAALGAV---VAVFG-----------SQR----AIGLTAVTGAVLLLRAR
MAV_4391|M.avium_104 SATVGAA--VTVLAG-----------APR--LCCLAFGTGTGALLLLRSR
Mflv_4960|M.gilvum_PYR-GCK SAALGAVVVAAATI-----------VSGASAGLCAGLCVAAGVVLILRRN
Mvan_1446|M.vanbaalenii_PYR-1 TAAAGGVTVAAVAG-----------PAESSTILAALFAADLGGLLVLRTR
MSMEG_1535|M.smegmatis_MC2_155 AAALGAVLVAAD-------------GCGSVTFAAIAFDAAIGLALLSRGR
TH_3996|M.thermoresistible__bu TAVIGTTLIALGGVLVGQAAREPGSGPGGPWWTGPLFTALLAAALVLRAR
MAB_3757|M.abscessus_ATCC_1997 VTAVGAMLAALTFSGAGG-----HHPTGAHRLSGVVLAGLIALAMMLRAR
MLBr_00047|M.leprae_Br4923 SGTLILCSGAIAVIVR-----------GHFFAHSLVVAFLLTVVCTFRSR
. . * .
Mb3478|M.bovis_AF2122/97 S-ADTRRSLVFAICGITTVA-TAFTVAADRALEHGPWIAALTAMLAAVAM
Rv3448|M.tuberculosis_H37Rv S-ADTRRSLVFAICGITTVA-TAFTVAADRALEHGPWIAALTAMLAAVAM
MMAR_1101|M.marinum_M AQVDGRSRLMFLIAGYVAGT-AAFAVAAPGLAQHGPWIAILTAALTALAL
MUL_0859|M.ulcerans_Agy99 AQVDGRSRLMFLIAGYVAGT-AAFAVAAPGLAQHGPWIAILTAALTALAL
MAV_4391|M.avium_104 G-GDGTRALVFAAGGIVTTA-TTFGVAAWSAPLPGPWVAATTATLVAAAL
Mflv_4960|M.gilvum_PYR-GCK SHADGVRRLWLGTSGFIACA-AAVPAVADAAPAQAFWLSVAVAGGCVAG-
Mvan_1446|M.vanbaalenii_PYR-1 SHVVVHRRIALGAAGSVSLL-AAFTVTVVAAPVHAPWLCACAAVLCVLA-
MSMEG_1535|M.smegmatis_MC2_155 SHASGRCRTVLGVTGFCALT-AMFVLVVAWSPPYGNWVGAAAVAVGLAA-
TH_3996|M.thermoresistible__bu SHADALRRGVLVGCGVGCAT-MAFTAVVIEHPGQASAWGALAVAIGLVA-
MAB_3757|M.abscessus_ATCC_1997 SHADLAQTVAINLGGIAIPA-AAFAFVAVAYPTAAVFTTVLAAIAAGSAI
MLBr_00047|M.leprae_Br4923 LYAERWCAWALLAAAVVIPTGLTVKLCIWYTQIAWLLLTSYLVAAIIALM
: . . .
Mb3478|M.bovis_AF2122/97 FLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLT
Rv3448|M.tuberculosis_H37Rv FLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLT
MMAR_1101|M.marinum_M HLGFIAPTRPPSPIACRLIDALEFSASASLLPLACWTCGVFSAVGGLGLT
MUL_0859|M.ulcerans_Agy99 HLGFIAPTRPPSPIACRLIDALEFSASASLLPLACWTCGVFSAVGGLGLT
MAV_4391|M.avium_104 YLGCAP--RTCSPVLSRAADLLEWLALAALVPLTCWIAGLYGTVRGLTLG
Mflv_4960|M.gilvum_PYR-GCK -ALRAGRPEPSNPALRHGIQVLEYVALAAVIPLAFWVSGVYGLVRDASLL
Mvan_1446|M.vanbaalenii_PYR-1 -VRGAGSPASPNPLAHRMIQVTEYAALVALVPLAFWVSGIYGLVRQLSLA
MSMEG_1535|M.smegmatis_MC2_155 -MCSLGPASLTNAGILRIADAAEYVALAAVAPLACWLAGIFDAVRGFGM-
TH_3996|M.thermoresistible__bu -AGGR-PSAPVSPLIRRAADVAECVVLAALAPLACWVAGVYGLVRGLALW
MAB_3757|M.abscessus_ATCC_1997 ALGFLVSARKYSPVARRTVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
MLBr_00047|M.leprae_Br4923 VFGATVRVRRVSPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF-
.. : : : . : *: * .* :. * :
Mb3478|M.bovis_AF2122/97 WT
Rv3448|M.tuberculosis_H37Rv WT
MMAR_1101|M.marinum_M WT
MUL_0859|M.ulcerans_Agy99 WT
MAV_4391|M.avium_104 --
Mflv_4960|M.gilvum_PYR-GCK --
Mvan_1446|M.vanbaalenii_PYR-1 --
MSMEG_1535|M.smegmatis_MC2_155 --
TH_3996|M.thermoresistible__bu --
MAB_3757|M.abscessus_ATCC_1997 --
MLBr_00047|M.leprae_Br4923 --