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M. thermoresistible (build 8) TH_2236 ()

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 4366696 - 4368249
length: 518

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2236-100% (518)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_3948-5e-2227.85% (517) PUTATIVE secretion protein Snm4
M. thermoresistible (build 8)TH_3996-1e-1020.08% (508) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3907-0.068.82% (510) transmembrane protein
M. gilvum PYR-GCKMflv_0764-0.072.48% (487) hypothetical protein Mflv_0764
M. tuberculosis H37RvRv3877-0.068.82% (510) transmembrane protein
M. leprae Br4923MLBr_00047-0.063.99% (511) hypothetical protein MLBr_00047
M. abscessus ATCC 19977MAB_3757-2e-2623.03% (508) hypothetical protein MAB_3757
M. marinum MMMAR_5452-0.067.01% (479) hypothetical protein MMAR_5452
M. avium 104MAV_2919snm8e-2223.58% (509) secretion protein Snm4
M. smegmatis MC2 155MSMEG_0068-0.075.40% (504) transmembrane protein
M. ulcerans Agy99MUL_1212-1e-2026.77% (508) transmembrane protein
M. vanbaalenii PYR-1Mvan_0081-0.073.41% (504) hypothetical protein Mvan_0081

CLUSTAL 2.0.9 multiple sequence alignment


Mb3907|M.bovis_AF2122/97            MSAPAVA------AGPTAAGATAARPATTRVTILTGR-RMTDLVLPAAVP
Rv3877|M.tuberculosis_H37Rv         MSAPAVA------AGPTAAGATAARPATTRVTILTGR-RMTDLVLPAAVP
MMAR_5452|M.marinum_M               ---------------------------------------MTDLVLPAAAP
MLBr_00047|M.leprae_Br4923          MSAPAVT------AGPATAGITPARPSATRVTILTGK-RMTDLVLPSTVS
TH_2236|M.thermoresistible__bu      LTATASASAPGAAATASGTGATPARPATTRVTILTGR-RMTDLVLPAAAP
MSMEG_0068|M.smegmatis_MC2_155      MTSTAAA-----ADTSS---VTPGRPSTTRVTILTGK-RMTDLVLPATAP
Mflv_0764|M.gilvum_PYR-GCK          ------------------------------MTILTGR-RMTDLVLPSAAP
Mvan_0081|M.vanbaalenii_PYR-1       MTATVAP------PTSSN--VTPGRPTTTRVTILTGR-RMTDLVLPSAAP
MUL_1212|M.ulcerans_Agy99           --------------------MSGTVMPIVRVAILADS-RLTEVALPAELP
MAB_3757|M.abscessus_ATCC_1997      -----------MTHAQSGAEQRSAVLELCRVSIQAER-TQVDLALPTSVP
MAV_2919|M.avium_104                --------MTAVVEVPQPDVEGISQPQAVVVGVMAGAGVQIGVLLDANAP
                                                                              : * :  .

Mb3907|M.bovis_AF2122/97            METYIDDTVAVLSEVLEDTPADVLGGFDFTAQGVWAFARPGSPPLKLDQS
Rv3877|M.tuberculosis_H37Rv         METYIDDTVAVLSEVLEDTPADVLGGFDFTAQGVWAFARPGSPPLKLDQS
MMAR_5452|M.marinum_M               MESYVDETVAILADLLEDTPAEVLAGFDFEAQGVWTFARPGFPPLKLDQS
MLBr_00047|M.leprae_Br4923          IEAYIDETVAVLSDLLEDAPADVLAGFDFSAQGVWTFARPGSPPMKLDQS
TH_2236|M.thermoresistible__bu      IESYIDETVSVLAELLEDTPSDVLAGFDFKAQGVWAFARPGAPPLKSDES
MSMEG_0068|M.smegmatis_MC2_155      IETYIDETVSFLAELLEDAPKDVLAGFNFGEQGVWAFARPGAPPLKADES
Mflv_0764|M.gilvum_PYR-GCK          IETYVDETVAVLGDILSDTPPDVLAGFDFTAQGVWSFARPGAPPIKLTDS
Mvan_0081|M.vanbaalenii_PYR-1       IETYVDETVSVLADILADTPENVLADFDFKAQGVWSFARPGAPPIKLTES
MUL_1212|M.ulcerans_Agy99           LREILPAVQRLVIPVAEDG---DAGSADLGIAGHLSLAPVGGAPFSLDAS
MAB_3757|M.abscessus_ATCC_1997      LALLVGSIVDIINQHVGVP---ELTSPEDAVETHWRLSRPGQPPLQMSST
MAV_2919|M.avium_104                VSVMTEPLLKVVNSRLRELG---ETPLEATGRGRWALCLVDGSPLRATQS
                                    :         .:               :        :.  . .*:    :

Mb3907|M.bovis_AF2122/97            LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRTAL
Rv3877|M.tuberculosis_H37Rv         LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRTAL
MMAR_5452|M.marinum_M               LDEAGVVDGSLLTLVLASRTERYRPLVEDVIDAIAVLDES--PEFNRTAL
MLBr_00047|M.leprae_Br4923          LDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNES--PEFNRKAV
TH_2236|M.thermoresistible__bu      LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDRSAL
MSMEG_0068|M.smegmatis_MC2_155      LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PVFDRTAL
Mflv_0764|M.gilvum_PYR-GCK          LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDRRAL
Mvan_0081|M.vanbaalenii_PYR-1       LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDRSAL
MUL_1212|M.ulcerans_Agy99           LDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRLRPWDARHL
MAB_3757|M.abscessus_ATCC_1997      LGELEVRDGDLLILTRS-DVAAPDPLFDDVFLAVSTFRTVSAHPWSR-NA
MAV_2919|M.avium_104                LSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLSKRFAAIDP-VV
                                    *.   * **. * :           :.:.:  *            .    

Mb3907|M.bovis_AF2122/97            NRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVG---S
Rv3877|M.tuberculosis_H37Rv         NRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVG---S
MMAR_5452|M.marinum_M               ERFLAVAIPLFALPITAVAMRAWWQTGRSVFWPLAIGLIGLAALAG---S
MLBr_00047|M.leprae_Br4923          DRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTG---S
TH_2236|M.thermoresistible__bu      NRYIAVAIPIVSLIVTIVGLLSWANSGQSWWWALGLGLLGLGVLGG---S
MSMEG_0068|M.smegmatis_MC2_155      KHFVAIALPIVATIITVATLIAWTRSGHGWWWAVALGVLGLGLLGG---S
Mflv_0764|M.gilvum_PYR-GCK          YRFVGLVLPLVALLTTVMAVLSWSSTGRDWWWAAALGVLGTGLLGG---S
Mvan_0081|M.vanbaalenii_PYR-1       YRFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGG---S
MUL_1212|M.ulcerans_Agy99           QRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAMALAG---L
MAB_3757|M.abscessus_ATCC_1997      ARILGASVCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTA---A
MAV_2919|M.avium_104                AVQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIGVLMLGVSVLL
                                           :           :                       :      

Mb3907|M.bovis_AF2122/97            FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
Rv3877|M.tuberculosis_H37Rv         FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
MMAR_5452|M.marinum_M               FVAKRFYQNSRLAESLLVTSYGVIAAAAAIAVPLPRGFHSLGAPQLAAAA
MLBr_00047|M.leprae_Br4923          IVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDSLGPPQVAAAA
TH_2236|M.thermoresistible__bu      MLAKSRYDNIDMTESLLVGSMPLLAGAAALAVPLPRGVTSLGAPQLAAVG
MSMEG_0068|M.smegmatis_MC2_155      MAAKSRYNSLDMSESLLLAATPALAGAVGLAVPLPRGVDGLGAPQLAGAA
Mflv_0764|M.gilvum_PYR-GCK          ALSQRRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVAGAG
Mvan_0081|M.vanbaalenii_PYR-1       VLAQNRYRHLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAG
MUL_1212|M.ulcerans_Agy99           LLGAR---SPRTGIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGVTA
MAB_3757|M.abscessus_ATCC_1997      VFANRVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGAPHAMLALMVAMV
MAV_2919|M.avium_104                LMRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGSPQAVLGFGVLTI
                                                   *   :      *     *   *             

Mb3907|M.bovis_AF2122/97            TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
Rv3877|M.tuberculosis_H37Rv         TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
MMAR_5452|M.marinum_M               TAVLFITLMMRGGPYKRHDIAAFVVITSIAVISAAVAFGYGYQQWVP-AG
MLBr_00047|M.leprae_Br4923          AAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQHWVP-TG
TH_2236|M.thermoresistible__bu      AVILLITLASRGGPRRRAELASFIAVTALAVTAAAVAYGYGWEYWVP-VG
MSMEG_0068|M.smegmatis_MC2_155      AVVLLLTLATRGGPRKRAEVASFVAVTSIAVTAAAIAFGYGWQEWVP-AG
Mflv_0764|M.gilvum_PYR-GCK          ALILLMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVP-AG
Mvan_0081|M.vanbaalenii_PYR-1       ALVLLMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFGYGWNDWVP-AG
MUL_1212|M.ulcerans_Agy99           WSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGVELLWQLPVSSIGCG
MAB_3757|M.abscessus_ATCC_1997      VSILAMRATGTG----TTSLVAVASASFLGFAAALGYVLFEPPIYSLGAV
MAV_2919|M.avium_104                AAVLALRFTGRR----LAIYTAIVTVSAIAALAALARMVAMTGAVTLLTC
                                      :: :              .:.                           

Mb3907|M.bovis_AF2122/97            GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
Rv3877|M.tuberculosis_H37Rv         GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
MMAR_5452|M.marinum_M               AIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPITAQ-DAT
MLBr_00047|M.leprae_Br4923          AVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEAT
TH_2236|M.thermoresistible__bu      AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDDLLDPVITP-DGS
MSMEG_0068|M.smegmatis_MC2_155      AIAFGLIVVTNAAKLTVAVARIALPPIPAPGEHVSNDELLDPVVTP-DSI
Mflv_0764|M.gilvum_PYR-GCK          AIAFGLIVVTNAAKMTVAVARIALPPIPAPGESVTNDELLDPVATT-DAS
Mvan_0081|M.vanbaalenii_PYR-1       AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDELLDPVTTT-DAS
MUL_1212|M.ulcerans_Agy99           LIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPS--------------
MAB_3757|M.abscessus_ATCC_1997      LGSVGICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLD
MAV_2919|M.avium_104                VVLVSVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPTTV----
                                        .:     :. ::   * : ** .*                      

Mb3907|M.bovis_AF2122/97            SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
Rv3877|M.tuberculosis_H37Rv         SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
MMAR_5452|M.marinum_M               NEETPTWQAIIASAPASAARLTERSKLAKQLLVGYVTAGTLILAVGSIAV
MLBr_00047|M.leprae_Br4923          HEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAV
TH_2236|M.thermoresistible__bu      DEETSTWQAIIASVPESAQRLQERSTLAKQLLIGFLTAGAVVLSAGAIAV
MSMEG_0068|M.smegmatis_MC2_155      DDASPTWQAIIASVPESAARLQERSQLTRQLLIGFLSAGALILTVGAIAV
Mflv_0764|M.gilvum_PYR-GCK          -EESETWQAIIASVPDSAARLTERSRLAKRLLIGFLSAGALILVLGSVFV
Mvan_0081|M.vanbaalenii_PYR-1       -EESETWQAIIASVPSSAARLTERSRLAKRLLIGFLSAGALILAAGSIAV
MUL_1212|M.ulcerans_Agy99           -----------APSLRVLEDLPRRVRVSDAHQSGFIAAAVLLSVLGSVAI
MAB_3757|M.abscessus_ATCC_1997      GLDTEGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSAVTAVGAMLA
MAV_2919|M.avium_104                --VRSDGGPPVLEGPASVRDVLTQAERARSFLSGLLIGLGVLMVVSLTAL
                                                        :  :   :     * : .   :   .    

Mb3907|M.bovis_AF2122/97            VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
Rv3877|M.tuberculosis_H37Rv         VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
MMAR_5452|M.marinum_M               VVHG---------HFFIHS-MIVAGLITVICSFRSRLYADPWCAWALLAA
MLBr_00047|M.leprae_Br4923          IVRG---------HFFAHS-LVVAFLLTVVCTFRSRLYAERWCAWALLAA
TH_2236|M.thermoresistible__bu      VVQG---------HFFVHS-LIVAGLVTMICAFRSRLYAERWCAWALLAA
MSMEG_0068|M.smegmatis_MC2_155      VVQG---------HFFVHS-MIVASLVTVICGFRSRLYAERWCAWALLAA
Mflv_0764|M.gilvum_PYR-GCK          VVQG---------HFFVHS-MIVAGLVTMLAGFRSRLYVERWCAWALMAA
Mvan_0081|M.vanbaalenii_PYR-1       VVQG---------HFFLHS-MIVAGLVTMLCGFRSRLYAERWCAWALMAA
MUL_1212|M.ulcerans_Agy99           ALRP---------DTVSALGWYVVAATAATATLRARIWDSAACKAWLLTQ
MAB_3757|M.abscessus_ATCC_1997      ALTFSGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQTVAINLG
MAV_2919|M.avium_104                SDPR---------TGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGT
                                                          :.   :    :*.*   .      :   

Mb3907|M.bovis_AF2122/97            TVAIP---TGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVRRV
Rv3877|M.tuberculosis_H37Rv         TVAIP---TGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVRRV
MMAR_5452|M.marinum_M               TVAIP---TGLAVKLSLWYPHYAWLLLTIYLAAALVTLISVGAMNQVRRV
MLBr_00047|M.leprae_Br4923          AVVIP---TGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVRRV
TH_2236|M.thermoresistible__bu      CTAIP---TGVMVKLCMWYPERAAVVLGIYVAAVLVAVIAVGATHGVRRM
MSMEG_0068|M.smegmatis_MC2_155      TVAVP---TGLMIKLSMWWPDSAWIVMGIYTMLALIALIVVGATDGVRRV
Mflv_0764|M.gilvum_PYR-GCK          AVAIP---SGIAVRMSLWYPDRAWWVLGIYTVAAAVALIVVGATDGVRRI
Mvan_0081|M.vanbaalenii_PYR-1       AVAVP---TGVVVRLCLWYPERAWLLLAIYTALALLAVIVIGASEGVRRI
MUL_1212|M.ulcerans_Agy99           PYLVGGTLLVLYAATGHFIAAFGALVVLAVLAVAWVVVALNPVIASPESY
MAB_3757|M.abscessus_ATCC_1997      GIAIP---AAAFAFVAVAYPT-AAVFTTVLAAIAAGSAIALGFLVSARKY
MAV_2919|M.avium_104                AVLIVG--AVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVY
                                       :               .  .  .       .                

Mb3907|M.bovis_AF2122/97            SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
Rv3877|M.tuberculosis_H37Rv         SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
MMAR_5452|M.marinum_M               SPVMKRALELFDGAMVASIVPLLLWITGVYDLVRNIRF-
MLBr_00047|M.leprae_Br4923          SPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF-
TH_2236|M.thermoresistible__bu      SPVTKRILELVDGAAIAATIPMLLWIGSVFDILRNIRF-
MSMEG_0068|M.smegmatis_MC2_155      SPVTKRILELFDGAAIAAVIPLLLWIAGVYDLLRNLRLH
Mflv_0764|M.gilvum_PYR-GCK          SPVTKRILELLDGATIAAVIPLLLWISGVYDVLRNLRF-
Mvan_0081|M.vanbaalenii_PYR-1       SPVTKRILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
MUL_1212|M.ulcerans_Agy99           SLPLRRLLGFLAAGLDASLIPVMAYLAGLFTWVLNR---
MAB_3757|M.abscessus_ATCC_1997      SPVARRTVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
MAV_2919|M.avium_104                SPLFRKFVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
                                    *   :: :  .        .*:  :: .::  :