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SAPAVTAGPATAGITPARPSATRVTILTGKRMTDLVLPSTVSIEAYIDETVAVLSDLLEDAPADVLAGFD FSAQGVWTFARPGSPPMKLDQSLDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNESPEFNRKAV DRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTGSIVAEKFYKNLDLSESLLLTSYPL IASAAALVTPLPNGVDSLGPPQVAAAAAAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQ HWVPTGAVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEATHEETPTWQAIIASV PDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAVIVRGHFFAHSLVVAFLLTVVCTFRSRLYAERWCA WALLAAAVVIPTGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVRRVSPVTKRIMELIDGAVVA SIIPLLLWIAGVYDMVRNLSF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00047 | - | - | 100% (512) | hypothetical protein MLBr_00047 |
| M. leprae Br4923 | MLBr_02529 | - | 2e-22 | 25.77% (520) | hypothetical protein MLBr_02529 |
| M. leprae Br4923 | MLBr_01539 | - | 5e-16 | 23.71% (523) | hypothetical protein MLBr_01539 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3907 | - | 0.0 | 74.22% (512) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0764 | - | 1e-179 | 62.50% (488) | hypothetical protein Mflv_0764 |
| M. tuberculosis H37Rv | Rv3877 | - | 0.0 | 74.22% (512) | transmembrane protein |
| M. abscessus ATCC 19977 | MAB_3757 | - | 1e-29 | 24.11% (506) | hypothetical protein MAB_3757 |
| M. marinum M | MMAR_5452 | - | 0.0 | 71.25% (480) | hypothetical protein MMAR_5452 |
| M. avium 104 | MAV_4863 | - | 1e-20 | 24.01% (504) | hypothetical protein MAV_4863 |
| M. smegmatis MC2 155 | MSMEG_0068 | - | 0.0 | 64.43% (506) | transmembrane protein |
| M. thermoresistible (build 8) | TH_2236 | - | 0.0 | 63.99% (511) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1212 | - | 2e-23 | 23.76% (505) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0081 | - | 0.0 | 62.40% (508) | hypothetical protein Mvan_0081 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3907|M.bovis_AF2122/97 MSAPAVA------AGPTAAGATAARPATTRVTILTGRRMTDLVLPAAVPM
Rv3877|M.tuberculosis_H37Rv MSAPAVA------AGPTAAGATAARPATTRVTILTGRRMTDLVLPAAVPM
MMAR_5452|M.marinum_M --------------------------------------MTDLVLPAAAPM
MLBr_00047|M.leprae_Br4923 MSAPAVT------AGPATAGITPARPSATRVTILTGKRMTDLVLPSTVSI
MSMEG_0068|M.smegmatis_MC2_155 MTSTAAA-----ADTSS---VTPGRPSTTRVTILTGKRMTDLVLPATAPI
TH_2236|M.thermoresistible__bu LTATASASAPGAAATASGTGATPARPATTRVTILTGRRMTDLVLPAAAPI
Mflv_0764|M.gilvum_PYR-GCK ------------------------------MTILTGRRMTDLVLPSAAPI
Mvan_0081|M.vanbaalenii_PYR-1 MTATVAP------PTSSN--VTPGRPTTTRVTILTGRRMTDLVLPSAAPI
MAV_4863|M.avium_104 -------------------MTSGTVMPIVRVAILADSRLTEMALPAELPL
MUL_1212|M.ulcerans_Agy99 --------------------MSGTVMPIVRVAILADSRLTEVALPAELPL
MAB_3757|M.abscessus_ATCC_1997 -----------MTHAQSGAEQRSAVLELCRVSIQAERTQVDLALPTSVPL
.::.**: .:
Mb3907|M.bovis_AF2122/97 ETYIDDTVAVLSEVLEDTP----ADVLGGFDFTAQGVWAFARPGSPPLKL
Rv3877|M.tuberculosis_H37Rv ETYIDDTVAVLSEVLEDTP----ADVLGGFDFTAQGVWAFARPGSPPLKL
MMAR_5452|M.marinum_M ESYVDETVAILADLLEDTP----AEVLAGFDFEAQGVWTFARPGFPPLKL
MLBr_00047|M.leprae_Br4923 EAYIDETVAVLSDLLEDAP----ADVLAGFDFSAQGVWTFARPGSPPMKL
MSMEG_0068|M.smegmatis_MC2_155 ETYIDETVSFLAELLEDAP----KDVLAGFNFGEQGVWAFARPGAPPLKA
TH_2236|M.thermoresistible__bu ESYIDETVSVLAELLEDTP----SDVLAGFDFKAQGVWAFARPGAPPLKS
Mflv_0764|M.gilvum_PYR-GCK ETYVDETVAVLGDILSDTP----PDVLAGFDFTAQGVWSFARPGAPPIKL
Mvan_0081|M.vanbaalenii_PYR-1 ETYVDETVSVLADILADTP----ENVLADFDFKAQGVWSFARPGAPPIKL
MAV_4863|M.avium_104 REILPAVQRLVVPAAANGDSEDGAPSRGAAEVGGAVQLSLAPIGGAPFSL
MUL_1212|M.ulcerans_Agy99 REILPAVQRLVIPVAEDGD-------AGSADLGIAGHLSLAPVGGAPFSL
MAB_3757|M.abscessus_ATCC_1997 ALLVGSIVDIINQHVGVPE-------LTSPEDAVETHWRLSRPGQPPLQM
: .: : :: * .*:.
Mb3907|M.bovis_AF2122/97 DQSLDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDR
Rv3877|M.tuberculosis_H37Rv DQSLDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDR
MMAR_5452|M.marinum_M DQSLDEAGVVDGSLLTLVLASRTERYRPLVEDVIDAIAVLDES--PEFNR
MLBr_00047|M.leprae_Br4923 DQSLDDAGVVDGSLLTLVSTSRTERYRPLVEDVIDAIAVLNES--PEFNR
MSMEG_0068|M.smegmatis_MC2_155 DESLDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PVFDR
TH_2236|M.thermoresistible__bu DESLDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAVLDES--PEFDR
Mflv_0764|M.gilvum_PYR-GCK TDSLDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDR
Mvan_0081|M.vanbaalenii_PYR-1 TESLDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAVLDET--PEFDR
MAV_4863|M.avium_104 DASLDTVGVVDGDLLALQPVPAGPAAPGIVEDIADAAMIFSTSRLRPWGT
MUL_1212|M.ulcerans_Agy99 DASLDTVGVVDGDLLVLQPVPTGPAAPGIVEDIADAAMIFSTSRLRPWDA
MAB_3757|M.abscessus_ATCC_1997 SSTLGELEVRDGDLLILTRS-DVAAPDPLFDDVFLAVSTFRTVSAHPWSR
:*. * **.** : :.:*: * : :.
Mb3907|M.bovis_AF2122/97 TALNRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVGS
Rv3877|M.tuberculosis_H37Rv TALNRFVGAAIPLLTAPVIGMAMRAWWETGRSLWWPLAIGILGIAVLVGS
MMAR_5452|M.marinum_M TALERFLAVAIPLFALPITAVAMRAWWQTGRSVFWPLAIGLIGLAALAGS
MLBr_00047|M.leprae_Br4923 KAVDRFIGVAIPVLSLPITAVAVWAWWVTGRSPFWSLAIGILSIVALTGS
MSMEG_0068|M.smegmatis_MC2_155 TALKHFVAIALPIVATIITVATLIAWTRSGHGWWWAVALGVLGLGLLGGS
TH_2236|M.thermoresistible__bu SALNRYIAVAIPIVSLIVTIVGLLSWANSGQSWWWALGLGLLGLGVLGGS
Mflv_0764|M.gilvum_PYR-GCK RALYRFVGLVLPLVALLTTVMAVLSWSSTGRDWWWAAALGVLGTGLLGGS
Mvan_0081|M.vanbaalenii_PYR-1 SALYRFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGGS
MAV_4863|M.avium_104 THIQRFALATVIAVALLATGLSVSYRVATGALAGLVAVSAVAALTAIVGL
MUL_1212|M.ulcerans_Agy99 RHLQRGALAALIGVALAGSGLAVAYRVATGALAGLLIVSVIAVAMALAGL
MAB_3757|M.abscessus_ATCC_1997 -NAARILGASVCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTAA
: : : : :. : .
Mb3907|M.bovis_AF2122/97 FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
Rv3877|M.tuberculosis_H37Rv FVANRFYQSGHLAECLLVTTYLLIATAAALAVPLPRGVNSLGAPQVAGAA
MMAR_5452|M.marinum_M FVAKRFYQNSRLAESLLVTSYGVIAAAAAIAVPLPRGFHSLGAPQLAAAA
MLBr_00047|M.leprae_Br4923 IVAEKFYKNLDLSESLLLTSYPLIASAAALVTPLPNGVDSLGPPQVAAAA
MSMEG_0068|M.smegmatis_MC2_155 MAAKSRYNSLDMSESLLLAATPALAGAVGLAVPLPRGVDGLGAPQLAGAA
TH_2236|M.thermoresistible__bu MLAKSRYDNIDMTESLLVGSMPLLAGAAALAVPLPRGVTSLGAPQLAAVG
Mflv_0764|M.gilvum_PYR-GCK ALSQRRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVAGAG
Mvan_0081|M.vanbaalenii_PYR-1 VLAQNRYRHLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAG
MAV_4863|M.avium_104 LATARSPRN---GMALSIAALVPIGAALALAVPGRFGPAQVMLAAAGVTA
MUL_1212|M.ulcerans_Agy99 LLGARSPRT---GIALSIAALAPVGAALALAVPGSFGAAQVLLAAAGVTA
MAB_3757|M.abscessus_ATCC_1997 VFANRVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGAPHAMLALMVAMV
* : * : .* * .
Mb3907|M.bovis_AF2122/97 TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
Rv3877|M.tuberculosis_H37Rv TAVLFLTLMTRGGPRKRHELASFAVITAIAVIAAAAAFGYGYQDWVP-AG
MMAR_5452|M.marinum_M TAVLFITLMMRGGPYKRHDIAAFVVITSIAVISAAVAFGYGYQQWVP-AG
MLBr_00047|M.leprae_Br4923 AAVLFLTLLTRGGARRHSGYASFTAITTIAIVVIAIAYGFGYQHWVP-TG
MSMEG_0068|M.smegmatis_MC2_155 AVVLLLTLATRGGPRKRAEVASFVAVTSIAVTAAAIAFGYGWQEWVP-AG
TH_2236|M.thermoresistible__bu AVILLITLASRGGPRRRAELASFIAVTALAVTAAAVAYGYGWEYWVP-VG
Mflv_0764|M.gilvum_PYR-GCK ALILLMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVP-AG
Mvan_0081|M.vanbaalenii_PYR-1 ALVLLMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFGYGWNDWVP-AG
MAV_4863|M.avium_104 WSLIALMAPSAERERLAGFFTATAVLGAAVLLAAGAELLWHITPVALGCG
MUL_1212|M.ulcerans_Agy99 WSLICLMVPGEQRERIVALFTAVAVVGAALLLAAGVELLWQLPVSSIGCG
MAB_3757|M.abscessus_ATCC_1997 VSILAMRATGTG----TTSLVAVASASFLGFAAALGYVLFEPPIYSLGAV
:: : .: . :
Mb3907|M.bovis_AF2122/97 GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
Rv3877|M.tuberculosis_H37Rv GIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVATP-EAT
MMAR_5452|M.marinum_M AIAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPITAQ-DAT
MLBr_00047|M.leprae_Br4923 AVAFGLFIVTNAAKLTVAVARIALPPIPVPGETVDNEELLDPVVTPHEAT
MSMEG_0068|M.smegmatis_MC2_155 AIAFGLIVVTNAAKLTVAVARIALPPIPAPGEHVSNDELLDPVVTP-DSI
TH_2236|M.thermoresistible__bu AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDDLLDPVITP-DGS
Mflv_0764|M.gilvum_PYR-GCK AIAFGLIVVTNAAKMTVAVARIALPPIPAPGESVTNDELLDPVATT-DAS
Mvan_0081|M.vanbaalenii_PYR-1 AIAFGLIVVTNAAKLTVAVARIALPPIPAPGETVTNDELLDPVTTT-DAS
MAV_4863|M.avium_104 LIVAALLVTVEAAPLSALWARFPLPVIPAPGDPTPSAPPLP---------
MUL_1212|M.ulcerans_Agy99 LIVAALLVTIQAAQLSAVWARFPLPVIPAPGDPTPSAPSLR---------
MAB_3757|M.abscessus_ATCC_1997 LGSVGICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLD
.: . :. :: **:.** :*. *
Mb3907|M.bovis_AF2122/97 SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
Rv3877|M.tuberculosis_H37Rv SEETPTWQAIIASVPASAVRLTERSKLAKQLLIGYVTSGTLILAAGAIAV
MMAR_5452|M.marinum_M NEETPTWQAIIASAPASAARLTERSKLAKQLLVGYVTAGTLILAVGSIAV
MLBr_00047|M.leprae_Br4923 HEETPTWQAIIASVPDSAVRLTERSSLAKRLLIGYVISGTLILCSGAIAV
MSMEG_0068|M.smegmatis_MC2_155 DDASPTWQAIIASVPESAARLQERSQLTRQLLIGFLSAGALILTVGAIAV
TH_2236|M.thermoresistible__bu DEETSTWQAIIASVPESAQRLQERSTLAKQLLIGFLTAGAVVLSAGAIAV
Mflv_0764|M.gilvum_PYR-GCK -EESETWQAIIASVPDSAARLTERSRLAKRLLIGFLSAGALILVLGSVFV
Mvan_0081|M.vanbaalenii_PYR-1 -EESETWQAIIASVPSSAARLTERSRLAKRLLIGFLSAGALILAAGSIAV
MAV_4863|M.avium_104 ---------VLEDLPR-------RVRIGDAHQSGFIAAAVLLSALGSVAI
MUL_1212|M.ulcerans_Agy99 ---------VLEDLPR-------RVRVSDAHQSGFIAAAVLLSVLGSVAI
MAB_3757|M.abscessus_ATCC_1997 GLDTEGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSAVTAVGAMLA
: * : . : *::
Mb3907|M.bovis_AF2122/97 VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
Rv3877|M.tuberculosis_H37Rv VVRG---------HFFVHS-LVVAGLITTVCGFRSRLYAERWCAWALLAA
MMAR_5452|M.marinum_M VVHG---------HFFIHS-MIVAGLITVICSFRSRLYADPWCAWALLAA
MLBr_00047|M.leprae_Br4923 IVRG---------HFFAHS-LVVAFLLTVVCTFRSRLYAERWCAWALLAA
MSMEG_0068|M.smegmatis_MC2_155 VVQG---------HFFVHS-MIVASLVTVICGFRSRLYAERWCAWALLAA
TH_2236|M.thermoresistible__bu VVQG---------HFFVHS-LIVAGLVTMICAFRSRLYAERWCAWALLAA
Mflv_0764|M.gilvum_PYR-GCK VVQG---------HFFVHS-MIVAGLVTMLAGFRSRLYVERWCAWALMAA
Mvan_0081|M.vanbaalenii_PYR-1 VVQG---------HFFLHS-MIVAGLVTMLCGFRSRLYAERWCAWALMAA
MAV_4863|M.avium_104 ALRP---------ETLSAAGWYVVGATAATSVLRARVWDSAACKAWLLAQ
MUL_1212|M.ulcerans_Agy99 ALRP---------DTVSALGWYVVAATAATATLRARIWDSAACKAWLLTQ
MAB_3757|M.abscessus_ATCC_1997 ALTFSGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQTVAINLG
: :. : :*:* . :
Mb3907|M.bovis_AF2122/97 TVAIPTGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVR---RV
Rv3877|M.tuberculosis_H37Rv TVAIPTGLTAKLIIWYPHYAWLLLSVYLTVALVALVVVGSMAHVR---RV
MMAR_5452|M.marinum_M TVAIPTGLAVKLSLWYPHYAWLLLTIYLAAALVTLISVGAMNQVR---RV
MLBr_00047|M.leprae_Br4923 AVVIPTGLTVKLCIWYTQIAWLLLTSYLVAAIIALMVFGATVRVR---RV
MSMEG_0068|M.smegmatis_MC2_155 TVAVPTGLMIKLSMWWPDSAWIVMGIYTMLALIALIVVGATDGVR---RV
TH_2236|M.thermoresistible__bu CTAIPTGVMVKLCMWYPERAAVVLGIYVAAVLVAVIAVGATHGVR---RM
Mflv_0764|M.gilvum_PYR-GCK AVAIPSGIAVRMSLWYPDRAWWVLGIYTVAAAVALIVVGATDGVR---RI
Mvan_0081|M.vanbaalenii_PYR-1 AVAVPTGVVVRLCLWYPERAWLLLAIYTALALLAVIVIGASEGVR---RI
MAV_4863|M.avium_104 PYLAAGVLLVLYTATGRYAGALGAVLVLLALVAVWIVVALNPGIAAPESY
MUL_1212|M.ulcerans_Agy99 PYLVGGTLLVLYAATGHFIAAFGALVVLAVLAVAWVVVALNPVIASPESY
MAB_3757|M.abscessus_ATCC_1997 GIAIPAAAFAFVAVAYP-TAAVFTTVLAAIAAGSAIALGFLVSAR---KY
. : ..
Mb3907|M.bovis_AF2122/97 SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
Rv3877|M.tuberculosis_H37Rv SPVVKRTLELIDGAMIAAIIPMLLWITGVYDTVRNIRF-
MMAR_5452|M.marinum_M SPVMKRALELFDGAMVASIVPLLLWITGVYDLVRNIRF-
MLBr_00047|M.leprae_Br4923 SPVTKRIMELIDGAVVASIIPLLLWIAGVYDMVRNLSF-
MSMEG_0068|M.smegmatis_MC2_155 SPVTKRILELFDGAAIAAVIPLLLWIAGVYDLLRNLRLH
TH_2236|M.thermoresistible__bu SPVTKRILELVDGAAIAATIPMLLWIGSVFDILRNIRF-
Mflv_0764|M.gilvum_PYR-GCK SPVTKRILELLDGATIAAVIPLLLWISGVYDVLRNLRF-
Mvan_0081|M.vanbaalenii_PYR-1 SPVTKRILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
MAV_4863|M.avium_104 SLPVRRLVGFVATGLDASLIPVMAFVVGLFGWVLDR---
MUL_1212|M.ulcerans_Agy99 SLPLRRLLGFLAAGLDASLIPVMAYLAGLFTWVLNR---
MAB_3757|M.abscessus_ATCC_1997 SPVARRTVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
* :* : :. : :*: :: .:: : .