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MIREEFPGERRPDFQDEVKPLLGDLHRRAYAYVRDTSDAEDLVQETLLRAYRAFDRLGDDYQLMPWLLAI MRNTWISRYRAAQRRPAEALVGEFLDTYAETASRGASGETWSAEDVAMRNMSDPAVVAALSKLPESLRLT MYYTAIVGMSCREVSTLMDIPKGTVMSRLHRGRHQMRRALSHHRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3296 | - | - | 100% (185) | ECF-family protein sigma factor H |
| M. smegmatis MC2 155 | MSMEG_0573 | - | 4e-33 | 42.77% (166) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_0574 | - | 1e-32 | 39.88% (173) | putative ECF sigma factor RpoE1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 5e-30 | 38.76% (178) | RNA polymerase sigma factor RpoE |
| M. gilvum PYR-GCK | Mflv_1078 | - | 9e-32 | 43.86% (171) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3223c | sigH | 5e-30 | 38.76% (178) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 5e-12 | 27.81% (169) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 1e-32 | 40.33% (181) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 2e-30 | 38.76% (178) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 3e-31 | 39.66% (179) | RNA polymerase sigma factor RpoE |
| M. thermoresistible (build 8) | TH_0665 | sigH | 2e-31 | 39.33% (178) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 2e-30 | 39.88% (168) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_5744 | - | 7e-36 | 45.83% (168) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3250c|M.bovis_AF2122/97 -----------------------------------------------MAD
Rv3223c|M.tuberculosis_H37Rv -----------------------------------------------MAD
MMAR_1334|M.marinum_M --------MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD
MUL_2545|M.ulcerans_Agy99 -----------------------------------------------MAD
MAV_4171|M.avium_104 -------MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMAD
TH_0665|M.thermoresistible__bu -----------------------------------------------MTD
MAB_3543c|M.abscessus_ATCC_199 ------------------------------MACLERPMSVP----IRMVG
Mflv_1078|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5744|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3296|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
Mb3250c|M.bovis_AF2122/97 ----IDGVTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLY
Rv3223c|M.tuberculosis_H37Rv ----IDGVTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLY
MMAR_1334|M.marinum_M ----IDGVTLAEAPDP--------EPPEETDEQLTARFERDAIPLLDQLY
MUL_2545|M.ulcerans_Agy99 ----IDGVTLAEAPDP--------EPPEETDEQLTACFERDAIPLLDQLY
MAV_4171|M.avium_104 SPDGPDGVTSPEVPEAHAEPAAHEETREETDAELTARFERDAIPLLDQLY
TH_0665|M.thermoresistible__bu ----IEGTTPIR--------------SEESDAELTARFERDAIPLLDQLY
MAB_3543c|M.abscessus_ATCC_199 VATERTAVTSMDSAAELPG-----LVHVETEAERVARFERDALPLLDQLY
Mflv_1078|M.gilvum_PYR-GCK --------------------------------MPTLLFERDVIPLIRALY
Mvan_5744|M.vanbaalenii_PYR-1 ------------------------MHTDRHDDQLTDRFERDAMPLIADLY
MSMEG_3296|M.smegmatis_MC2_155 ------------------------MIREEFPGERRPDFQDEVKPLLGDLH
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
:: . ::
Mb3250c|M.bovis_AF2122/97 GGALRMTRNPADAEDLLQETMVKAYAGFRS---FRHGTNLKAWLYRILTN
Rv3223c|M.tuberculosis_H37Rv GGALRMTRNPADAEDLLQETMVKAYAGFRS---FRHGTNLKAWLYRILTN
MMAR_1334|M.marinum_M GGALRMTRNPADAEDLLQETMVKAYAGFRS---FREGTNLKAWLYRILTN
MUL_2545|M.ulcerans_Agy99 GGALRMTRNPADAEDLLQETMVKAYAGFRS---FREGTNLKAWLYRILTN
MAV_4171|M.avium_104 GGALRMTRNPADAEDLLQETMVKAYAGFRS---FRAGTNLKAWLYRILTN
TH_0665|M.thermoresistible__bu GGALRMTRNPADAEDLLQETMVKAYQGFRS---FREGTNLKAWLYRILTN
MAB_3543c|M.abscessus_ATCC_199 GAALRMTRNPADAEDLVQETMVKAYAGFGT---FKEGTNLKAWLYRILTN
Mflv_1078|M.gilvum_PYR-GCK PHAYRLTREHADAEDLLQETSVKAYRAFGSAVLVGEGTNLAGWLYRIMRN
Mvan_5744|M.vanbaalenii_PYR-1 RHAIRLTRDHADAEDLLQETAAKAYAAFAS---FQEGTNLVGWLYRIMVN
MSMEG_3296|M.smegmatis_MC2_155 RRAYAYVRDTSDAEDLVQETLLRAYRAFDR---LGDDYQLMPWLLAIMRN
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSVQN----YQPGTFEGWLHRITTN
* : ***** *** :.: .. : ** * *
Mb3250c|M.bovis_AF2122/97 TYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPD
Rv3223c|M.tuberculosis_H37Rv TYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPD
MMAR_1334|M.marinum_M TYINSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPD
MUL_2545|M.ulcerans_Agy99 TYINSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPD
MAV_4171|M.avium_104 TYINSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLPD
TH_0665|M.thermoresistible__bu TYINNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTGLRSAEVEALEALPD
MAB_3543c|M.abscessus_ATCC_199 TYINIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLPD
Mflv_1078|M.gilvum_PYR-GCK THLSAYRRRLCRPALQFTGEVTGG-----------VARSTEDVVLTAAGD
Mvan_5744|M.vanbaalenii_PYR-1 THISAYRRQQHRPTLQFTDEFTDGQLLAHSQRGSSATRSTEELAIAHTGD
MSMEG_3296|M.smegmatis_MC2_155 TWISRYRAAQRRPAEALVGEFLDTYAETASRGASGETWSAEDVAMRNMSD
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIRMDALPDDYDRVP---------ADEPNPEQIYHDSRLG
:. * : ..* .
Mb3250c|M.bovis_AF2122/97 TEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
Rv3223c|M.tuberculosis_H37Rv TEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
MMAR_1334|M.marinum_M TEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
MUL_2545|M.ulcerans_Agy99 TEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
MAV_4171|M.avium_104 SEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
TH_0665|M.thermoresistible__bu TEIKAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
MAB_3543c|M.abscessus_ATCC_199 DEIKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGR
Mflv_1078|M.gilvum_PYR-GCK PAVAAAMRALPEKYRTAVYYADVEGRTFREIAELVDVPIGTVMSRLHRGR
Mvan_5744|M.vanbaalenii_PYR-1 PAIAAAMRSLPEKYRTAIYYADIEGRKFREIALLTNVPIGTVMSRLHRGR
MSMEG_3296|M.smegmatis_MC2_155 PAVVAALSKLPESLRLTMYYTAIVGMSCREVSTLMDIPKGTVMSRLHRGR
MLBr_01076|M.leprae_Br4923 PDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGR
: *: ** . * :: : * .*:. . *** **:****
Mb3250c|M.bovis_AF2122/97 RQLRGLLADVARDRGFARGEQA--HEGVSS
Rv3223c|M.tuberculosis_H37Rv RQLRGLLADVARDRGFARGEQA--HEGVSS
MMAR_1334|M.marinum_M RQLRTLLADVAKERGFVRGEQA--HQEVSS
MUL_2545|M.ulcerans_Agy99 RQLRTLLADVAKERGFVRGEQA--HQEVSS
MAV_4171|M.avium_104 RQLRGLLADVAKERGFNRGQQT--HEEVSS
TH_0665|M.thermoresistible__bu RQLRSLLADVARERGIIRDQQAGTPEEVSS
MAB_3543c|M.abscessus_ATCC_199 RQLRDLLSEVAKDRGFLRNNEL--AEGRA-
Mflv_1078|M.gilvum_PYR-GCK MRLRVALADVARDRGYPLFEAA--------
Mvan_5744|M.vanbaalenii_PYR-1 KQLRDALSDVARDRGYPLPEAA--------
MSMEG_3296|M.smegmatis_MC2_155 HQMRRALSHHRS------------------
MLBr_01076|M.leprae_Br4923 QALRDYLLTAHPRDGATTDATHVKSA----
:* *