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M. avium 104 MAV_5256 (-)

SPRTSNGLPVTAYLVLGVLAANDERLTAGEIKTRAELSVGHFYWSPSVSHVRRELTRLLARGMVAQTGAQ
SGKRAITLYETTDAGRDALRRWVQHFPGQDQVVIKHPVILKTWLARGEDPERIVDTLERHLDATRARLDE
ALWSRRRSQELGITEDPEQRFSFAVLDYAIRGLYAEISNISQLRDEIAGGTSRDPVKRVRRSKGQIRRRA
PRSPG*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_5256	-	-	100% (216)	hypothetical protein MAV_5256
M. avium 104	MAV_3044	-	2e-16	30.59% (170)	transcriptional regulator, PadR family protein
M. avium 104	MAV_0135	-	6e-06	27.09% (203)	transcriptional regulator, PadR family protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_4568	-	4e-09	29.37% (126)	PadR-like family transcriptional regulator
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_0082c	-	6e-18	31.22% (189)	hypothetical protein MAB_0082c
M. marinum M	MMAR_1544	-	3e-07	31.01% (129)	hypothetical protein MMAR_1544
M. smegmatis MC2 155	MSMEG_2868	-	3e-11	31.16% (138)	transcriptional regulator, PadR family protein
M. thermoresistible (build 8)	TH_0324	-	2e-09	28.67% (143)	transcriptional regulator, PadR family protein
M. ulcerans Agy99	MUL_2388	-	3e-07	33.68% (95)	hypothetical protein MUL_2388
M. vanbaalenii PYR-1	Mvan_2867	-	1e-08	30.00% (120)	PadR-like family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2868|M.smegmatis_MC2_155      MTDAADTPLG-ELNVSPTGWALLGMLSG-GDELSGYDIKKWINWAIQFFY
Mvan_2867|M.vanbaalenii_PYR-1       --------------MSPTGWALLGMLSG-GEEMSGYDIKKWINWAIRFFY
TH_0324|M.thermoresistible__bu      VTEAVEDAAD-QPNLSPTGWALLGMLSG-GNELSGYDIKKWTDWVIRFFY
Mflv_4568|M.gilvum_PYR-GCK          MTDSADSGSGRKPGLAATSYALLGLLSY-EQELSGYDIRKWIGWTMRFYY
MAB_0082c|M.abscessus_ATCC_199      --MAAISSPG-EPNLAATSWTILGMLSY-EEEVSGYDIKKWADWSISYFY
MMAR_1544|M.marinum_M               ----------MTPQPTASSFAVLGLLG--VQPWTAYELVAQSKRSLHWFW
MUL_2388|M.ulcerans_Agy99           ----------MTPQPTASSFAVLGLLG--VQPWTAYELVAQSKRSLHWFW
MAV_5256|M.avium_104                ------MSPRTSNGLPVTAYLVLGVLAANDERLTAGEIKTRAELSVGHFY
                                                   . :.: :**:*.   :  :. ::       :  ::

MSMEG_2868|M.smegmatis_MC2_155      SSPAYSQIYSELKRLERLGLVSSRVD--AGARSRRMYKITDAGLSAVTRW
Mvan_2867|M.vanbaalenii_PYR-1       SSPAYSQIYSELKRLERLGLVSSRVD--AGVRSRRMYKITESGLAAVTRW
TH_0324|M.thermoresistible__bu      SSPAYSQIYSELKRLEQYGLVTSRIE--GSTRSRRMYKITDAGLAAVTRW
Mflv_4568|M.gilvum_PYR-GCK          GSPAYSQIYSELKKLESLGLVTSRVESTGGARSRRLYKIAPAGLDEVIRW
MAB_0082c|M.abscessus_ATCC_199      WSPSFSQVYSELRKLEKIGYATSRVDHDNGARSRRLYKITPAGMAAMSQW
MMAR_1544|M.marinum_M               PR-SERHLYAELKRLVERGHAEAHVE--GGRRRRTRYTITPAGRAALQAW
MUL_2388|M.ulcerans_Agy99           PR-SERHLYAELKRLVERGHAEAHVE--GGRRRRTRYTITPAGRAALQAW
MAV_5256|M.avium_104                WSPSVSHVRRELTRLLARGMVAQTGAQ-SGKRAITLYETTDAGRDALRRW
                                       :  ::  ** :*   * .        . *    *  : :*   :  *

MSMEG_2868|M.smegmatis_MC2_155      ANEEAVE-PPTLKHNPVLRVMLGHLLKPGRLREVLAEHADYADRMHQAAA
Mvan_2867|M.vanbaalenii_PYR-1       ANEDPVE-APTLKHNPILRMMLGHLLKPGRLREILAGHAAYAEQLQQAAA
TH_0324|M.thermoresistible__bu      TNEEPVE-APTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADRMQREAA
Mflv_4568|M.gilvum_PYR-GCK          ANDEPFD-PPSLKHGPLLRMTFGHLSTPARLKELLNEHIAYADEMEREAA
MAB_0082c|M.abscessus_ATCC_199      ANETPAE-PQVLKHSVVLRVMQGHMTDPARLKEILERHIEYAENMQRRAA
MMAR_1544|M.marinum_M               LGTEPA--PPTLEIEGLLRVMLADQGNMDDLRAAVEATARQARTVRAEGL
MUL_2388|M.ulcerans_Agy99           LGTEPA--PPTLEIEGLVRVMLADQGNMDDLRAAVEATARQARTVRAEGL
MAV_5256|M.avium_104                VQHFPGQDQVVIKHPVILKTWLARGEDPERIVDTLERHLDATRARLDEAL
                                        .      ::   :::   .       :   :      :      . 

MSMEG_2868|M.smegmatis_MC2_155      TEARWTEDQPAWSYAGLAL-RWSERYYAAERELALQMIKDLDAVEAQLAE
Mvan_2867|M.vanbaalenii_PYR-1       TEVRWTSEQPAWSYARLAL-KWSEQYYAAERELALQMIKDLDAAEEAFGE
TH_0324|M.thermoresistible__bu      TEARHTAEQPAWSYARLAL-QWSERYYAAERDLALQLIKDLDVADRIFTE
Mflv_4568|M.gilvum_PYR-GCK          KDARLAGADPSWAYARVAL-RWAERYYANERELALQMIKDLDEAEAEFPR
MAB_0082c|M.abscessus_ATCC_199      LDAAGAAAQPAWAYSRVAL-KWAERYYAAERDLAMMMIEDLAEAAEEFDK
MMAR_1544|M.marinum_M               PLVAELLATGGPFPQRLHLNERLVSFYSDFNNLLLRWCEETLADVETWQG
MUL_2388|M.ulcerans_Agy99           PFVAELLATGGPFPQRLHLNERLVSFYSDFNNLLLRWCEETLADVETWQG
MAV_5256|M.avium_104                WSRRRSQELGITEDPEQRFSFAVLDYAIRGLYAEISNISQLRDEIAGGTS
                                                      :      :        :   .:          

MSMEG_2868|M.smegmatis_MC2_155      TGA---QNMEFPVREYWYEVERRIAAEETDETPPGAQRPD-
Mvan_2867|M.vanbaalenii_PYR-1       AGR---EGVQFPMPEYWYEVERRIAAEDT----PGVEDPSA
TH_0324|M.thermoresistible__bu      AEQ---SGLEWPVREYWYEVERRIAAEKD------RE----
Mflv_4568|M.gilvum_PYR-GCK          AAHGDQAAVAWPEPAYWYEVEQRAQSEADS-----------
MAB_0082c|M.abscessus_ATCC_199      AGP--DGGTPRLVPGYWREVEKRVDAEKLSTQHDTAD----
MMAR_1544|M.marinum_M               TQD------IGLTPSGRQRLVRAISEHP-------------
MUL_2388|M.ulcerans_Agy99           TQD------IGLTPSGRQRLVRAISEDP-------------
MAV_5256|M.avium_104                RDP------VKRVRRSKGQIRRRAPRSPG------------
                                                      .: :