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ASETDPASQKPALAATSWALLGMMSYEEEVSGYDLKKWIDWSVDLYYWSPSYSQIYTELKKLEALGLVTS RVERDEGTRSRRLYKITPAGMDAVTQWTNHAPVDPPVLKHSVLLRVTFGHLSNPGRLKELLQEHVAYAEA RHRKAMEDAEGAEAEPAWAYSVLALRWAAKYYAAEREFALEMIKEIDEADAILQRAAKGGYGKPRPTPGY WREVEKQVQAKREAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3044 | - | - | 100% (226) | transcriptional regulator, PadR family protein |
| M. avium 104 | MAV_5256 | - | 2e-16 | 30.59% (170) | hypothetical protein MAV_5256 |
| M. avium 104 | MAV_0135 | - | 6e-11 | 31.30% (115) | transcriptional regulator, PadR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 3e-05 | 28.17% (71) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_4568 | - | 5e-76 | 60.73% (219) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 3e-05 | 28.17% (71) | hypothetical protein Rv1176c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0082c | - | 8e-78 | 59.64% (223) | hypothetical protein MAB_0082c |
| M. marinum M | MMAR_3454 | - | 6e-14 | 31.25% (176) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2868 | - | 3e-64 | 53.99% (213) | transcriptional regulator, PadR family protein |
| M. thermoresistible (build 8) | TH_0324 | - | 8e-68 | 54.30% (221) | transcriptional regulator, PadR family protein |
| M. ulcerans Agy99 | MUL_2728 | - | 5e-14 | 33.89% (180) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2867 | - | 1e-61 | 53.11% (209) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3044|M.avium_104 -MASETDPASQKPALAATSWALLGMMSYEEEVSGYDLKKWIDWSVDLYYW
MAB_0082c|M.abscessus_ATCC_199 -MAAISSPG--EPNLAATSWTILGMLSYEEEVSGYDIKKWADWSISYFYW
MSMEG_2868|M.smegmatis_MC2_155 MTDAADTPLG-ELNVSPTGWALLGMLSGGDELSGYDIKKWINWAIQFFYS
Mvan_2867|M.vanbaalenii_PYR-1 --------------MSPTGWALLGMLSGGEEMSGYDIKKWINWAIRFFYS
TH_0324|M.thermoresistible__bu VTEAVEDAAD-QPNLSPTGWALLGMLSGGNELSGYDIKKWTDWVIRFFYS
Mflv_4568|M.gilvum_PYR-GCK MTDSADSGSGRKPGLAATSYALLGLLSYEQELSGYDIRKWIGWTMRFYYG
MMAR_3454|M.marinum_M ---------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP
MUL_2728|M.ulcerans_Agy99 ---------------MSLRHAALGLLS-QEPGSGYDLLKRFQLSMNNVWP
Mb1209c|M.bovis_AF2122/97 ---------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT
Rv1176c|M.tuberculosis_H37Rv ---------------MALPHAILVSLC-EQASSGYELARRFDRSIGYFWT
. : * :. : ***:: : : :
MAV_3044|M.avium_104 SPSYSQIYTELKKLEALGLVTSRVERDEGTRSRRLYKITPAGMDAVTQWT
MAB_0082c|M.abscessus_ATCC_199 SPSFSQVYSELRKLEKIGYATSRVDHDNGARSRRLYKITPAGMAAMSQWA
MSMEG_2868|M.smegmatis_MC2_155 SPAYSQIYSELKRLERLGLVSSRVD--AGARSRRMYKITDAGLSAVTRWA
Mvan_2867|M.vanbaalenii_PYR-1 SPAYSQIYSELKRLERLGLVSSRVD--AGVRSRRMYKITESGLAAVTRWA
TH_0324|M.thermoresistible__bu SPAYSQIYSELKRLEQYGLVTSRIE--GSTRSRRMYKITDAGLAAVTRWT
Mflv_4568|M.gilvum_PYR-GCK SPAYSQIYSELKKLESLGLVTSRVESTGGARSRRLYKIAPAGLDEVIRWA
MMAR_3454|M.marinum_M -ATQSQLYSELNKLAAAGLIKSSDL---GPRGRKEYAITDAGRAELYRWM
MUL_2728|M.ulcerans_Agy99 -ATQSQLYSELNKLAAAGLIKSSDL---GPRGRKEYAITDAGRAELYRWM
Mb1209c|M.bovis_AF2122/97 -ATHQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWI
Rv1176c|M.tuberculosis_H37Rv -ATHQQIYRTLRVMENNNWVRATTVLQHGRPDKKVYAISDSGRAELARWI
.: .*:* *. : . : . .:: * *: :* : :*
MAV_3044|M.avium_104 NHAPVDPPVLKHSVLLRVTFGHLSNPGRLKELLQEHVAYAEA--RHRKAM
MAB_0082c|M.abscessus_ATCC_199 NETPAEPQVLKHSVVLRVMQGHMTDPARLKEILERHIEYAEN--MQRRAA
MSMEG_2868|M.smegmatis_MC2_155 NEEAVEPPTLKHNPVLRVMLGHLLKPGRLREVLAEHADYADR--MHQAAA
Mvan_2867|M.vanbaalenii_PYR-1 NEDPVEAPTLKHNPILRMMLGHLLKPGRLREILAGHAAYAEQ--LQQAAA
TH_0324|M.thermoresistible__bu NEEPVEAPTLKHSPMLRVVFGHLTNPGRLKEVLAEHAAYADR--MQREAA
Mflv_4568|M.gilvum_PYR-GCK NDEPFDPPSLKHGPLLRMTFGHLSTPARLKELLNEHIAYADE--MEREAA
MMAR_3454|M.marinum_M TSPQQDPP-VRNAALLRVFLLGQLDPSQARSYLESLLSLSEQEKTHYEQI
MUL_2728|M.ulcerans_Agy99 TSPQQDPP-VRNAALLRVFLLGQLDPSQAGSYLESLLSLSEQEKTHYERI
Mb1209c|M.bovis_AF2122/97 AEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERV
Rv1176c|M.tuberculosis_H37Rv AEPLSPTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERV
. : : : :: .
MAV_3044|M.avium_104 EDAEGAEAEPAWAYSVLALRWAAKYYAAEREFALEMIKEIDEADAILQRA
MAB_0082c|M.abscessus_ATCC_199 LDAAGAAAQPAWAYSRVALKWAERYYAAERDLAMMMIEDLAEAAEEFDKA
MSMEG_2868|M.smegmatis_MC2_155 TEARWTEDQPAWSYAGLALRWSERYYAAERELALQMIKDLDAVEAQLAET
Mvan_2867|M.vanbaalenii_PYR-1 TEVRWTSEQPAWSYARLALKWSEQYYAAERELALQMIKDLDAAEEAFGEA
TH_0324|M.thermoresistible__bu TEARHTAEQPAWSYARLALQWSERYYAAERDLALQLIKDLDVADRIFTEA
Mflv_4568|M.gilvum_PYR-GCK KDARLAGADPSWAYARVALRWAERYYANERELALQMIKDLDEAEAEFPRA
MMAR_3454|M.marinum_M RDAYDWAEDDDSFFARAALEQGLRWAQQEIEWAKWVIAGLDQRSGVAPAG
MUL_2728|M.ulcerans_Agy99 RYAYDWAEDDDSFFARAAPEQGLRWAQQEIEWAKWVIAGLDQRSGVAPAG
Mb1209c|M.bovis_AF2122/97 KSLDTYRGIEKRTFADPS-----ALDGAALHQYLVLRGGIRAEESAID--
Rv1176c|M.tuberculosis_H37Rv KSLDTYRGIEKRTFADPS-----ALDGAALHQYLVLRGGIRAEESAID--
:: : . : :
MAV_3044|M.avium_104 AK-GGYGKPRPTPGYWREVEKQVQAKREAE----------
MAB_0082c|M.abscessus_ATCC_199 GP-DG-GTPRLVPGYWREVEKRVDAEKLSTQHDTAD----
MSMEG_2868|M.smegmatis_MC2_155 GA---QNMEFPVREYWYEVERRIAAEETDETPPGAQRPD-
Mvan_2867|M.vanbaalenii_PYR-1 GR---EGVQFPMPEYWYEVERRIAAEDT----PGVEDPSA
TH_0324|M.thermoresistible__bu EQ---SGLEWPVREYWYEVERRIAAEKD------RE----
Mflv_4568|M.gilvum_PYR-GCK AHGDQAAVAWPEPAYWYEVEQRAQSEADS-----------
MMAR_3454|M.marinum_M QG--------------------------------------
MUL_2728|M.ulcerans_Agy99 QG--------------------------------------
Mb1209c|M.bovis_AF2122/97 --------------WLDEVAEALQEKR-------------
Rv1176c|M.tuberculosis_H37Rv --------------WLDEVAEALQEKR-------------