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MSQSLTGKVALITGAARGQGRAHAARLAAEGADIIAVDLAGPLPPSVPYDSSTPEDLAATAELVRAAGRR VVTAQTDVRDLDALTSSVDRAVGELGRLDVIVANAGICSPAPWNRITAQAFRDTIDTNVVGTWNTVMAGA QHIIDGGRGGSIILIGSAAGINMQSFMVHYTASKHAVVGMARAFAAELGRYNIRVNSLNPGAVATPMGTG RMRDALRAAADDYPHLRGLHKPLLPEGIAQPEDIADAVAWLASDQSRLVTASQVSVDLGVGYV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5244 | - | - | 100% (273) | cholesterol oxidase |
| M. avium 104 | MAV_3098 | - | e-120 | 80.38% (265) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_1570 | - | 1e-95 | 63.94% (269) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 1e-56 | 47.45% (274) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4371 | - | 1e-99 | 66.79% (265) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 1e-56 | 47.45% (274) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 8e-22 | 29.12% (261) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_3844c | - | 4e-59 | 43.75% (272) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-61 | 48.90% (272) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_2204 | - | 1e-107 | 72.12% (269) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. thermoresistible (build 8) | TH_3169 | - | 3e-97 | 66.17% (269) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 2e-53 | 45.93% (270) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1973 | - | 6e-98 | 66.42% (265) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4371|M.gilvum_PYR-GCK ------MRLEGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPC
Mvan_1973|M.vanbaalenii_PYR-1 -----MSRLEGRVAFITGAARGQGRAHAVRMATEGADIIAVDIAGPLPPC
MSMEG_2204|M.smegmatis_MC2_155 ----MAERLTGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPS
TH_3169|M.thermoresistible__bu ----MTGRLAGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPDC
MAV_5244|M.avium_104 ----MSQSLTGKVALITGAARGQGRAHAARLAAEGADIIAVDLAGPLPPS
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MAB_3844c|M.abscessus_ATCC_199 ---MADQPLAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAPVSEY
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGK-----PAFVSRSILVTGGNRGIGLA
.* ..** * *: * . .::. . :
Mflv_4371|M.gilvum_PYR-GCK VPYDHATADDLAETVELVKATGRRIIASAVDTRDGDALTAAVDSGVAELG
Mvan_1973|M.vanbaalenii_PYR-1 VPYDHATPDDLAETVKLVEATGRRILASKVDTRDGEALRATVEKGVAELG
MSMEG_2204|M.smegmatis_MC2_155 VPYDSATPEDLAETTRLVEATGRRILAARADTRDLEALRDVVGKGVAEFG
TH_3169|M.thermoresistible__bu VPYEPATPEDLDETVRLVTATGRRIHAAVADTRDLDGLREAVDAGVAALG
MAV_5244|M.avium_104 VPYDSSTPEDLAATAELVRAAGRRVVTAQTDVRDLDALTSSVDRAVGELG
Mb2771|M.bovis_AF2122/97 VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
Rv2750|M.tuberculosis_H37Rv VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
MAB_3844c|M.abscessus_ATCC_199 AGYEAATPEDLKETVRLVEAAGRKIIAEQADVRNGAALQSVVEEAVAQFG
MLBr_01807|M.leprae_Br4923 VARRLVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQG
. : . .. . . *. : .: . *
Mflv_4371|M.gilvum_PYR-GCK RLDIIVANAGVTAP-QAWDDISAEDFRDVIDVNVTGTWNTVMAGAHKIVD
Mvan_1973|M.vanbaalenii_PYR-1 RLDVIVANAGITAP-QAWDDIGADDFRDVMDVNVTGTWNTVMAGAHKIID
MSMEG_2204|M.smegmatis_MC2_155 RLDVIVANAGITVP-EPWNETTPESFRDVMDINVTGTWNTVMAGAQHIID
TH_3169|M.thermoresistible__bu RLDVIVANAGICAP-QTWDAITPADFRDVMDINVTGTWNTVMAGARHIID
MAV_5244|M.avium_104 RLDVIVANAGICSP-APWNRITAQAFRDTIDTNVVGTWNTVMAGAQHIID
Mb2771|M.bovis_AF2122/97 RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
Rv2750|M.tuberculosis_H37Rv RLDIVVANAGIA-----MMQAGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIA-----PMQSGDDGWRDVIDVNLSGAYYTVEVAIPTMIE
MMAR_4754|M.marinum_M RLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLIA
MAB_3844c|M.abscessus_ATCC_199 HIDILIANAGVLSW-GRLWEMSDQQWEDIIDTNLTGTWKTVKAVVPTMIE
MLBr_01807|M.leprae_Br4923 PVEVLVANAGITSD-MLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
:::::****: :.. :* *: *.: . ::
Mflv_4371|M.gilvum_PYR-GCK GGRGGSIILISSAAGIK----LQPFMIHYTASKHAVTGMARAFAAELGKH
Mvan_1973|M.vanbaalenii_PYR-1 GGRGGSIILISSAAGIK----LQPFMIHYTASKHAVTGMARAFAAELGKH
MSMEG_2204|M.smegmatis_MC2_155 GGRGGSIILISSAAGIK----MQPFMVHYTASKHAVAGMARAFAAELGKH
TH_3169|M.thermoresistible__bu GRRGGSIILISSLAGMK----LQPFMVHYTTSKHAVAGMARAFAAELGRH
MAV_5244|M.avium_104 GGRGGSIILIGSAAGIN----MQSFMVHYTASKHAVVGMARAFAAELGRY
Mb2771|M.bovis_AF2122/97 QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
Rv2750|M.tuberculosis_H37Rv QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
MUL_3392|M.ulcerans_Agy99 QGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPH
MMAR_4754|M.marinum_M GGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELGQH
MAB_3844c|M.abscessus_ATCC_199 AGNGGSIVIVSSVSGLKG----TPGNGAYVASKFGLTGLTKSLTIELAEY
MLBr_01807|M.leprae_Br4923 QRFG-RYIFMGSVVGLSG----VPGQANYAASKSGLIGMARSLARELGSR
* :: .* *: *.::* .: *: : : *.
Mflv_4371|M.gilvum_PYR-GCK SIRVNSVHPGPVVTDMGTGD-----MVTALGKAMETNPQLSNMMTPFLPT
Mvan_1973|M.vanbaalenii_PYR-1 SIRVNSVHPGPVLTDMGTGD-----MVTALGKAMETNPQLSNMMTPFLPT
MSMEG_2204|M.smegmatis_MC2_155 RIRVNSLHPGAVNTPMGTGD-----MLAALTRANDTNPGLMQMVTPFLPD
TH_3169|M.thermoresistible__bu RIRVNSLHPGAVATDMGGGE-----MVSALAATGESNPPLTQMITPFLPD
MAV_5244|M.avium_104 NIRVNSLNPGAVATPMGTGR-----MRDALRAAADDYPHLRGLHKPLLPE
Mb2771|M.bovis_AF2122/97 NIRVNSVHPCGVDTPMINNE----FFQQWLT---TADMDAPHNLGNALPV
Rv2750|M.tuberculosis_H37Rv NIRVNSVHPCGVDTPMINNE----FFQQWLT---TADMDAPHNLGNALPV
MUL_3392|M.ulcerans_Agy99 SIRVNSLHPSGVDPPMINNE----FIRHWLADL-VAETGSGPGAGNALPV
MMAR_4754|M.marinum_M MIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLPI
MAB_3844c|M.abscessus_ATCC_199 GIRVNSIHPYGVTTPMITGD----AMMKILAEHPNYLPSIAP--MPLSPT
MLBr_01807|M.leprae_Br4923 SITANVVAPGFIDTEMTRAM---------------DSKYQEAALQAIPLG
* .* : * : . *
Mflv_4371|M.gilvum_PYR-GCK WAVEPEDIADAVCWLASDESKFVTASAISVDQGSTHY-
Mvan_1973|M.vanbaalenii_PYR-1 WAVEPEDIADAVCWLASDESKFVTASAISVDQGSTHY-
MSMEG_2204|M.smegmatis_MC2_155 YIAEPEDIADAAVWLASDESRFVTASRVAVDLGSTQF-
TH_3169|M.thermoresistible__bu WIAQVDDIADAAVWLASDESRFVTAAKIPVDMGSSQF-
MAV_5244|M.avium_104 GIAQPEDIADAVAWLASDQSRLVTASQVSVDLGVGYV-
Mb2771|M.bovis_AF2122/97 ELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv ELVQPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 QILQADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
MMAR_4754|M.marinum_M PWVEAEDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MAB_3844c|M.abscessus_ATCC_199 KMLEPDEISDVVLWLASDASGTLAGAQVPVDKGHLTY-
MLBr_01807|M.leprae_Br4923 RIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
:*:.. :*.*: : ::. :.** *