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AGKLEGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPSCVPYDPASPEDLSETVRLVEAANRRI VAAVVDTRDFDGLRKVVDDGVAALGRLDIIVANAGVAAPQAWDDITPEDFRDVMDINVTGTWNTVMAGAP RIIEGGRGGSIILISSAAGMKMQPFMIHYTASKHAVTGLARAFAAELGKHSIRVNSVHPGPVNTPMGSGD MVTAVGQAMETNPQLSHVLTPFLPDWVAEPEDIADTVCWLASDESRKVTAAQIPVDQGSTQY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1570 | - | - | 100% (273) | carveol dehydrogenase |
| M. avium 104 | MAV_2636 | - | e-100 | 68.67% (249) | carveol dehydrogenase |
| M. avium 104 | MAV_3098 | - | 1e-97 | 66.29% (264) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0706 | fabG | 2e-67 | 48.72% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4371 | - | 1e-125 | 80.37% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0687 | fabG | 2e-67 | 48.72% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-22 | 31.68% (202) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3844c | - | 3e-65 | 46.47% (269) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 4e-67 | 50.54% (279) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_2204 | - | 1e-116 | 74.73% (273) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. thermoresistible (build 8) | TH_3169 | - | 1e-120 | 76.56% (273) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 8e-60 | 46.49% (271) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1973 | - | 1e-125 | 80.37% (270) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0706|M.bovis_AF2122/97 -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
Rv0687|M.tuberculosis_H37Rv -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
MAB_3844c|M.abscessus_ATCC_199 -MADQP--LAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAPVSEY
Mflv_4371|M.gilvum_PYR-GCK ------MRLEGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPC
Mvan_1973|M.vanbaalenii_PYR-1 -----MSRLEGRVAFITGAARGQGRAHAVRMATEGADIIAVDIAGPLPPC
MAV_1570|M.avium_104 ----MAGKLEGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPSC
MSMEG_2204|M.smegmatis_MC2_155 ----MAERLTGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPS
TH_3169|M.thermoresistible__bu ----MTGRLAGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPDC
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MLBr_01740|M.leprae_Br4923 -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
. *: .*:**** . ** *:*:* **:: *
Mb0706|M.bovis_AF2122/97 VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
Rv0687|M.tuberculosis_H37Rv VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
MAB_3844c|M.abscessus_ATCC_199 AGYEAATPEDLKETVRLVEAAGRKIIAE-QADVRNGAALQSVVEEAVAQF
Mflv_4371|M.gilvum_PYR-GCK VPYDHATADDLAETVELVKATGRRIIAS-AVDTRDGDALTAAVDSGVAEL
Mvan_1973|M.vanbaalenii_PYR-1 VPYDHATPDDLAETVKLVEATGRRILAS-KVDTRDGEALRATVEKGVAEL
MAV_1570|M.avium_104 VPYDPASPEDLSETVRLVEAANRRIVAA-VVDTRDFDGLRKVVDDGVAAL
MSMEG_2204|M.smegmatis_MC2_155 VPYDSATPEDLAETTRLVEATGRRILAA-RADTRDLEALRDVVGKGVAEF
TH_3169|M.thermoresistible__bu VPYEPATPEDLDETVRLVTATGRRIHAA-VADTRDLDGLREAVDAGVAAL
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGVDEL
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGIDEL
MLBr_01740|M.leprae_Br4923 ------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARH
: * *. . . :: * : :
Mb0706|M.bovis_AF2122/97 GRLDIVVANAGVLGWGRLWELTDEQ-WETVIGVNLTGTWRTLRATVPAMI
Rv0687|M.tuberculosis_H37Rv GRLDIVVANAGVLGWGRLWELTDEQ-WETVIGVNLTGTWRTLRATVPAMI
MAB_3844c|M.abscessus_ATCC_199 GHIDILIANAGVLSWGRLWEMSDQQ-WEDIIDTNLTGTWKTVKAVVPTMI
Mflv_4371|M.gilvum_PYR-GCK GRLDIIVANAGVTAP-QAWDDISAEDFRDVIDVNVTGTWNTVMAGAHKIV
Mvan_1973|M.vanbaalenii_PYR-1 GRLDVIVANAGITAP-QAWDDIGADDFRDVMDVNVTGTWNTVMAGAHKII
MAV_1570|M.avium_104 GRLDIIVANAGVAAP-QAWDDITPEDFRDVMDINVTGTWNTVMAGAPRII
MSMEG_2204|M.smegmatis_MC2_155 GRLDVIVANAGITVP-EPWNETTPESFRDVMDINVTGTWNTVMAGAQHII
TH_3169|M.thermoresistible__bu GRLDVIVANAGICAP-QTWDAITPADFRDVMDINVTGTWNTVMAGARHII
MMAR_4754|M.marinum_M GRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLI
MUL_3392|M.ulcerans_Agy99 GQVDIVVANAGIAP-----MQSGDDGWRDVIDVNLSGAYYTVEVAIPTMI
MLBr_01740|M.leprae_Br4923 PSMDIVMNIAGVSVWG-TVDRLTHDQWSNVVAINLMGPIHIIETFVPAIL
:*::: **: : :: *: * : . ::
Mb0706|M.bovis_AF2122/97 DAGNGGSIVVVSSSAGLKATPGNGH----YAASKHALVALTNTLAIELGE
Rv0687|M.tuberculosis_H37Rv DAGNGGSIVVVSSSAGLKATPGNGH----YAASKHALVALTNTLAIELGE
MAB_3844c|M.abscessus_ATCC_199 EAGNGGSIVIVSSVSGLKGTPGNGA----YVASKFGLTGLTKSLTIELAE
Mflv_4371|M.gilvum_PYR-GCK DGGRGGSIILISSAAGIKLQPFMIH----YTASKHAVTGMARAFAAELGK
Mvan_1973|M.vanbaalenii_PYR-1 DGGRGGSIILISSAAGIKLQPFMIH----YTASKHAVTGMARAFAAELGK
MAV_1570|M.avium_104 EGGRGGSIILISSAAGMKMQPFMIH----YTASKHAVTGLARAFAAELGK
MSMEG_2204|M.smegmatis_MC2_155 DGGRGGSIILISSAAGIKMQPFMVH----YTASKHAVAGMARAFAAELGK
TH_3169|M.thermoresistible__bu DGRRGGSIILISSLAGMKLQPFMVH----YTTSKHAVAGMARAFAAELGR
MMAR_4754|M.marinum_M AGGNGGSIVLTSSVGGMKAYPHCGN----YVAAKHGVVGLMRSFAVELGQ
MUL_3392|M.ulcerans_Agy99 EQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAP
MLBr_01740|M.leprae_Br4923 AAGRGGHLVNVSSAAGLVALPWHAA----YSASKYGLRGLSEVLRFDLAR
.** :: ** .*: . * ::*..: .: . *.
Mb0706|M.bovis_AF2122/97 FGIRVNSIHPYSVDTPMIEPEAMIQTFAKHPGYVHSFPPMP------LQP
Rv0687|M.tuberculosis_H37Rv FGIRVNSIHPYSVDTPMIEPEAMIQTFAKHPGYVHSFPPMP------LQP
MAB_3844c|M.abscessus_ATCC_199 YGIRVNSIHPYGVTTPMITGDAMMKILAEHPNYLPSIAPMP------LSP
Mflv_4371|M.gilvum_PYR-GCK HSIRVNSVHPGPVVTDMGTGDMVTALGKAMETNPQLSNMMT-----PFLP
Mvan_1973|M.vanbaalenii_PYR-1 HSIRVNSVHPGPVLTDMGTGDMVTALGKAMETNPQLSNMMT-----PFLP
MAV_1570|M.avium_104 HSIRVNSVHPGPVNTPMGSGDMVTAVGQAMETNPQLSHVLT-----PFLP
MSMEG_2204|M.smegmatis_MC2_155 HRIRVNSLHPGAVNTPMGTGDMLAALTRANDTNPGLMQMVT-----PFLP
TH_3169|M.thermoresistible__bu HRIRVNSLHPGAVATDMGGGEMVSALAATGESNPPLTQMIT-----PFLP
MMAR_4754|M.marinum_M HMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLP
MUL_3392|M.ulcerans_Agy99 HSIRVNSLHPSGVDPPMINNEFIRHWLADLVAETGSGPGAG-----NALP
MLBr_01740|M.leprae_Br4923 YRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERA
. * *. : * * . : .
Mb0706|M.bovis_AF2122/97 KGFMTPDEISDVVVWLAGDGSGALSGNQ----------------------
Rv0687|M.tuberculosis_H37Rv KGFMTPDEISDVVVWLAGDGSGALSGNQ----------------------
MAB_3844c|M.abscessus_ATCC_199 TKMLEPDEISDVVLWLASDASGTLAGAQ----------------------
Mflv_4371|M.gilvum_PYR-GCK TWAVEPEDIADAVCWLASDESKFVTASA----------------------
Mvan_1973|M.vanbaalenii_PYR-1 TWAVEPEDIADAVCWLASDESKFVTASA----------------------
MAV_1570|M.avium_104 DWVAEPEDIADTVCWLASDESRKVTAAQ----------------------
MSMEG_2204|M.smegmatis_MC2_155 DYIAEPEDIADAAVWLASDESRFVTASR----------------------
TH_3169|M.thermoresistible__bu DWIAQVDDIADAAVWLASDESRFVTAAK----------------------
MMAR_4754|M.marinum_M IPWVEAEDISNAVLFLASDESRYITGVT----------------------
MUL_3392|M.ulcerans_Agy99 VQILQADDIAGALAWLVSDEARYITGVA----------------------
MLBr_01740|M.leprae_Br4923 AEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRAL
. ... : .
Mb0706|M.bovis_AF2122/97 ----------IPVDKGALKY-----------
Rv0687|M.tuberculosis_H37Rv ----------IPVDKGALKY-----------
MAB_3844c|M.abscessus_ATCC_199 ----------VPVDKGHLTY-----------
Mflv_4371|M.gilvum_PYR-GCK ----------ISVDQGSTHY-----------
Mvan_1973|M.vanbaalenii_PYR-1 ----------ISVDQGSTHY-----------
MAV_1570|M.avium_104 ----------IPVDQGSTQY-----------
MSMEG_2204|M.smegmatis_MC2_155 ----------VAVDLGSTQF-----------
TH_3169|M.thermoresistible__bu ----------IPVDMGSSQF-----------
MMAR_4754|M.marinum_M ----------LPVDAGGCLK-----------
MUL_3392|M.ulcerans_Agy99 ----------LPVDAGCVNKR----------
MLBr_01740|M.leprae_Br4923 RPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
.:. *