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AERLTGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPSVPYDSATPEDLAETTRLVEATGRRI LAARADTRDLEALRDVVGKGVAEFGRLDVIVANAGITVPEPWNETTPESFRDVMDINVTGTWNTVMAGAQ HIIDGGRGGSIILISSAAGIKMQPFMVHYTASKHAVAGMARAFAAELGKHRIRVNSLHPGAVNTPMGTGD MLAALTRANDTNPGLMQMVTPFLPDYIAEPEDIADAAVWLASDESRFVTASRVAVDLGSTQF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2204 | - | - | 100% (273) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 7e-68 | 48.91% (276) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1410 | fabG | 5e-67 | 45.23% (283) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0706 | fabG | 2e-64 | 46.86% (271) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4371 | - | 1e-116 | 75.19% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0687 | fabG | 2e-64 | 46.86% (271) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 2e-21 | 29.95% (207) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3844c | - | 6e-64 | 45.86% (266) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 2e-66 | 48.90% (272) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1570 | - | 1e-116 | 74.73% (273) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3169 | - | 1e-117 | 76.92% (273) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_3392 | fabG | 6e-60 | 46.89% (273) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1973 | - | 1e-119 | 78.15% (270) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0706|M.bovis_AF2122/97 -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
Rv0687|M.tuberculosis_H37Rv -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
MAB_3844c|M.abscessus_ATCC_199 -MADQP--LAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAPVSEY
MSMEG_2204|M.smegmatis_MC2_155 ----MAERLTGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPS
TH_3169|M.thermoresistible__bu ----MTGRLAGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPDC
Mflv_4371|M.gilvum_PYR-GCK ------MRLEGRVAFITGAARGQGRAHAVRMAKEGADIIAVDIAGPLPPC
Mvan_1973|M.vanbaalenii_PYR-1 -----MSRLEGRVAFITGAARGQGRAHAVRMATEGADIIAVDIAGPLPPC
MAV_1570|M.avium_104 ----MAGKLEGRVAFITGAARGQGRAHAVRMAAEGADIIAVDIAGKLPSC
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MLBr_01740|M.leprae_Br4923 -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
. *: .*:**** . ** *:*:* **:: *
Mb0706|M.bovis_AF2122/97 VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
Rv0687|M.tuberculosis_H37Rv VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
MAB_3844c|M.abscessus_ATCC_199 AGYEAATPEDLKETVRLVEAAGRKIIAE-QADVRNGAALQSVVEEAVAQF
MSMEG_2204|M.smegmatis_MC2_155 VPYDSATPEDLAETTRLVEATGRRILAA-RADTRDLEALRDVVGKGVAEF
TH_3169|M.thermoresistible__bu VPYEPATPEDLDETVRLVTATGRRIHAA-VADTRDLDGLREAVDAGVAAL
Mflv_4371|M.gilvum_PYR-GCK VPYDHATADDLAETVELVKATGRRIIAS-AVDTRDGDALTAAVDSGVAEL
Mvan_1973|M.vanbaalenii_PYR-1 VPYDHATPDDLAETVKLVEATGRRILAS-KVDTRDGEALRATVEKGVAEL
MAV_1570|M.avium_104 VPYDPASPEDLSETVRLVEAANRRIVAA-VVDTRDFDGLRKVVDDGVAAL
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTA-EADVRDYDALKAAVDAGVDEL
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVAS-QADVRDREALAAALQAGIDEL
MLBr_01740|M.leprae_Br4923 ------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARH
: * *. . . :: * : :
Mb0706|M.bovis_AF2122/97 GRLDIVVANAGVLGW-GRLWELTDEQWETVIGVNLTGTWRTLRATVPAMI
Rv0687|M.tuberculosis_H37Rv GRLDIVVANAGVLGW-GRLWELTDEQWETVIGVNLTGTWRTLRATVPAMI
MAB_3844c|M.abscessus_ATCC_199 GHIDILIANAGVLSW-GRLWEMSDQQWEDIIDTNLTGTWKTVKAVVPTMI
MSMEG_2204|M.smegmatis_MC2_155 GRLDVIVANAGITVP-EPWNETTPESFRDVMDINVTGTWNTVMAGAQHII
TH_3169|M.thermoresistible__bu GRLDVIVANAGICAP-QTWDAITPADFRDVMDINVTGTWNTVMAGARHII
Mflv_4371|M.gilvum_PYR-GCK GRLDIIVANAGVTAP-QAWDDISAEDFRDVIDVNVTGTWNTVMAGAHKIV
Mvan_1973|M.vanbaalenii_PYR-1 GRLDVIVANAGITAP-QAWDDIGADDFRDVMDVNVTGTWNTVMAGAHKII
MAV_1570|M.avium_104 GRLDIIVANAGVAAP-QAWDDITPEDFRDVMDINVTGTWNTVMAGAPRII
MMAR_4754|M.marinum_M GRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLI
MUL_3392|M.ulcerans_Agy99 GQVDIVVANAGIAPM-----QSGDDGWRDVIDVNLSGAYYTVEVAIPTMI
MLBr_01740|M.leprae_Br4923 PSMDIVMNIAGVSVW-GTVDRLTHDQWSNVVAINLMGPIHIIETFVPAIL
:*::: **: : :: *: * : . ::
Mb0706|M.bovis_AF2122/97 DAGNGGSIVVVSSSAGLK----ATPGNGHYAASKHALVALTNTLAIELGE
Rv0687|M.tuberculosis_H37Rv DAGNGGSIVVVSSSAGLK----ATPGNGHYAASKHALVALTNTLAIELGE
MAB_3844c|M.abscessus_ATCC_199 EAGNGGSIVIVSSVSGLK----GTPGNGAYVASKFGLTGLTKSLTIELAE
MSMEG_2204|M.smegmatis_MC2_155 DGGRGGSIILISSAAGIK----MQPFMVHYTASKHAVAGMARAFAAELGK
TH_3169|M.thermoresistible__bu DGRRGGSIILISSLAGMK----LQPFMVHYTTSKHAVAGMARAFAAELGR
Mflv_4371|M.gilvum_PYR-GCK DGGRGGSIILISSAAGIK----LQPFMIHYTASKHAVTGMARAFAAELGK
Mvan_1973|M.vanbaalenii_PYR-1 DGGRGGSIILISSAAGIK----LQPFMIHYTASKHAVTGMARAFAAELGK
MAV_1570|M.avium_104 EGGRGGSIILISSAAGMK----MQPFMIHYTASKHAVTGLARAFAAELGK
MMAR_4754|M.marinum_M AGGNGGSIVLTSSVGGMK----AYPHCGNYVAAKHGVVGLMRSFAVELGQ
MUL_3392|M.ulcerans_Agy99 EQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAP
MLBr_01740|M.leprae_Br4923 AAGRGGHLVNVSSAAGLV----ALPWHAAYSASKYGLRGLSEVLRFDLAR
.** :: ** .*: . * ::*..: .: . *.
Mb0706|M.bovis_AF2122/97 FGIRVNSIHPYSVDTPMIEP---EAMIQTFAKHPGYVHSFPP---MPLQP
Rv0687|M.tuberculosis_H37Rv FGIRVNSIHPYSVDTPMIEP---EAMIQTFAKHPGYVHSFPP---MPLQP
MAB_3844c|M.abscessus_ATCC_199 YGIRVNSIHPYGVTTPMITG---DAMMKILAEHPNYLPSIAP---MPLSP
MSMEG_2204|M.smegmatis_MC2_155 HRIRVNSLHPGAVNTPMGTGDMLAALTRANDTNPGLMQMVTP-----FLP
TH_3169|M.thermoresistible__bu HRIRVNSLHPGAVATDMGGGEMVSALAATGESNPPLTQMITP-----FLP
Mflv_4371|M.gilvum_PYR-GCK HSIRVNSVHPGPVVTDMGTGDMVTALGKAMETNPQLSNMMTP-----FLP
Mvan_1973|M.vanbaalenii_PYR-1 HSIRVNSVHPGPVLTDMGTGDMVTALGKAMETNPQLSNMMTP-----FLP
MAV_1570|M.avium_104 HSIRVNSVHPGPVNTPMGSGDMVTAVGQAMETNPQLSHVLTP-----FLP
MMAR_4754|M.marinum_M HMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLP
MUL_3392|M.ulcerans_Agy99 HSIRVNSLHPSGVDPPMINNEFIRHWLADLVAETGSGPGAGN-----ALP
MLBr_01740|M.leprae_Br4923 YRIGVSVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERA
. * *. : * * . : . .
Mb0706|M.bovis_AF2122/97 KGFMTPDEISDVVVWLAGDGSGALSGNQ----------------------
Rv0687|M.tuberculosis_H37Rv KGFMTPDEISDVVVWLAGDGSGALSGNQ----------------------
MAB_3844c|M.abscessus_ATCC_199 TKMLEPDEISDVVLWLASDASGTLAGAQ----------------------
MSMEG_2204|M.smegmatis_MC2_155 DYIAEPEDIADAAVWLASDESRFVTASR----------------------
TH_3169|M.thermoresistible__bu DWIAQVDDIADAAVWLASDESRFVTAAK----------------------
Mflv_4371|M.gilvum_PYR-GCK TWAVEPEDIADAVCWLASDESKFVTASA----------------------
Mvan_1973|M.vanbaalenii_PYR-1 TWAVEPEDIADAVCWLASDESKFVTASA----------------------
MAV_1570|M.avium_104 DWVAEPEDIADTVCWLASDESRKVTAAQ----------------------
MMAR_4754|M.marinum_M IPWVEAEDISNAVLFLASDESRYITGVT----------------------
MUL_3392|M.ulcerans_Agy99 VQILQADDIAGALAWLVSDEARYITGVA----------------------
MLBr_01740|M.leprae_Br4923 AEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRAL
. ... : .
Mb0706|M.bovis_AF2122/97 ----------IPVDKGALKY-----------
Rv0687|M.tuberculosis_H37Rv ----------IPVDKGALKY-----------
MAB_3844c|M.abscessus_ATCC_199 ----------VPVDKGHLTY-----------
MSMEG_2204|M.smegmatis_MC2_155 ----------VAVDLGSTQF-----------
TH_3169|M.thermoresistible__bu ----------IPVDMGSSQF-----------
Mflv_4371|M.gilvum_PYR-GCK ----------ISVDQGSTHY-----------
Mvan_1973|M.vanbaalenii_PYR-1 ----------ISVDQGSTHY-----------
MAV_1570|M.avium_104 ----------IPVDQGSTQY-----------
MMAR_4754|M.marinum_M ----------LPVDAGGCLK-----------
MUL_3392|M.ulcerans_Agy99 ----------LPVDAGCVNKR----------
MLBr_01740|M.leprae_Br4923 RPSPATMRCVEPIKVGVYSQPRSGEGGKSGN
.:. *