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MTAAAARAVRFDRYGGREVLYVADIEMPAPGPGEVVVEVRAAGINPGEAAIRVGALHERFPATFPSGEGS DLAGVVTAVGPGVTEFAVGDEVLGFSLRRSSHATHTAVPVGQLIRKPPELSWEVAGSLYVVGVTAYAAVR AVAPQPGETVAVSAAAGGVGSLVTQLLVLRKARVLGIAGPGNADWLRAHGVVPIAYGDGLTDRLREAAPD GIDAFIDLFGPQYVQLAVDLGVPPERIDTIISFEKAAEVGAKTEGSAEASTPEVLAEMADLIVSGALEFD IAATYPLDRVADAFAELEQRHTHGKIVLLPTDSQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5196 | - | - | 100% (314) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. avium 104 | MAV_3325 | - | 5e-23 | 30.27% (337) | quinone oxidoreductase |
| M. avium 104 | MAV_4021 | - | 2e-20 | 28.70% (324) | oxidoreductase, zinc-binding dehydrogenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1489c | qor | 4e-22 | 30.21% (341) | quinone reductase |
| M. gilvum PYR-GCK | Mflv_3686 | - | 2e-23 | 28.49% (337) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv1454c | qor | 4e-22 | 30.21% (341) | quinone reductase |
| M. leprae Br4923 | MLBr_00118 | - | 3e-15 | 26.80% (306) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_0750 | - | 9e-99 | 58.82% (306) | putative oxidoreductase |
| M. marinum M | MMAR_1738 | - | 2e-25 | 32.88% (295) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6747 | - | 7e-68 | 45.07% (304) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3440 | - | 3e-24 | 28.91% (339) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_1855 | qor | 1e-23 | 30.09% (349) | quinone reductase Qor |
| M. vanbaalenii PYR-1 | Mvan_5758 | - | 3e-27 | 34.38% (317) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5758|M.vanbaalenii_PYR-1 -----------------------------------------------MRA
MAV_5196|M.avium_104 ------------------------------------------MTAAAARA
MAB_0750|M.abscessus_ATCC_1997 ----------------------------------------------MTKA
MSMEG_6747|M.smegmatis_MC2_155 ----------------------------------------------MPRT
Mb1489c|M.bovis_AF2122/97 -----------------------------------------------MHA
Rv1454c|M.tuberculosis_H37Rv -----------------------------------------------MHA
MUL_1855|M.ulcerans_Agy99 ----------------------------------------MVGHDSGVHA
Mflv_3686|M.gilvum_PYR-GCK --------------------------------------------MVDMYA
TH_3440|M.thermoresistible__bu VQTAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKA
MMAR_1738|M.marinum_M -----------------------------------------------MRA
MLBr_00118|M.leprae_Br4923 --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1 AVLTAYNSP--LLVDELPDPEPGPGEVLVRVMASGVNPLDIKIRRGE-AP
MAV_5196|M.avium_104 VRFDRYGGREVLYVADIEMPAPGPGEVVVEVRAAGINPGEAAIRVGALHE
MAB_0750|M.abscessus_ATCC_1997 VQFDQYGGIDVLQVRDVPRPVPAPDEVLVQVRAAGINPGEAKIRAGMLHD
MSMEG_6747|M.smegmatis_MC2_155 VQFAEYGDTDVLTVVDTPAPEPGPGQVRLKVRAAGLNPIDWKIVAGFMRE
Mb1489c|M.bovis_AF2122/97 IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRS----G
Rv1454c|M.tuberculosis_H37Rv IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRS----G
MUL_1855|M.ulcerans_Agy99 IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRS----G
Mflv_3686|M.gilvum_PYR-GCK IEVAETGGPEVLSFVETSRPSPGPGQVLIKAEAIGVNFIDTYFRS----G
TH_3440|M.thermoresistible__bu IEVRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRS----G
MMAR_1738|M.marinum_M LRAHRRGGPETLAVERAPVPVPAAGEVVVAVRAAGITFDELTWDQTWTRD
MLBr_00118|M.leprae_Br4923 MHAIVAESANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAG--KY
. : .. .:: : . * *:. :
Mvan_5758|M.vanbaalenii_PYR-1 HAQLPPPAVLGIDMAGVVEAVG-----PRVDRFTVGDEVFGMTGGVGGLQ
MAV_5196|M.avium_104 RFPATFPSGEGSDLAGVVTAVG-----PGVTEFAVGDEVLGFSLRRS---
MAB_0750|M.abscessus_ATCC_1997 RFPATFPSGQGSDLAGVVVEAG-----HGVARFAPGDEVFGYTDNRA---
MSMEG_6747|M.smegmatis_MC2_155 LMPVDLPAGVGSDVAGIVDAVG-----PGVTEWAVGNEVLGRSATG----
Mb1489c|M.bovis_AF2122/97 QYPRELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANG----
Rv1454c|M.tuberculosis_H37Rv QYPRELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANG----
MUL_1855|M.ulcerans_Agy99 SYPRELPFVIGSEVCGTVVAVGPGATAADAGGIAVGDRVVSASANG----
Mflv_3686|M.gilvum_PYR-GCK LYPRETPFIAGSEVCGVIEEVG-----EDVAALNVGDRVVTTQSQG----
TH_3440|M.thermoresistible__bu LYPREVPFIVGTEVCGTVEAVG-----DGVAALRVGDRVLTDKANG----
MMAR_1738|M.marinum_M GVS-RTPVIPSHEVSGVIHEIG-----SGTEDFHCGDEVYGLIGFDR--D
MLBr_00118|M.leprae_Br4923 PHPPGASAIIGMEVAGVVAAVS-----SGVTEWSVGQEVCALLAGG----
. . ::.* : . . *:.*
Mvan_5758|M.vanbaalenii_PYR-1 GSLAELAAVDARLIAHKPRTLSMAQAAALPLGFITSWEGLVDRAGVGTGQ
MAV_5196|M.avium_104 -SHATHTAVPVGQLIRKPPELSWEVAGSLYVVGVTAYAAVRAVAPQP-GE
MAB_0750|M.abscessus_ATCC_1997 -SHAEFVVVPASQLVTKPEGLSWEVAGSLFVAGTTAYAAVGSVHLSP-GD
MSMEG_6747|M.smegmatis_MC2_155 -AYAEYALAEAAELIGKPGEITWEVAGSLAGAGGTAHAVLDRLDLKS-GE
Mb1489c|M.bovis_AF2122/97 -AYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGD
Rv1454c|M.tuberculosis_H37Rv -AYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGD
MUL_1855|M.ulcerans_Agy99 -GYAEFCTAPAALTAKVPDVVSAEVAASALLKGLTAHYLLKSVCPVADGD
Mflv_3686|M.gilvum_PYR-GCK -AYAEYCVAPADFVAYVPDAVAPEVAASALLKGMTAHYLLKSTYPVQQGD
TH_3440|M.thermoresistible__bu -AYAEYTVAPADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGD
MMAR_1738|M.marinum_M GAAADFVAVPAAHLAAKPATISHTVAAALPLAGLTALQALVDHAAVRPGE
MLBr_00118|M.leprae_Br4923 -GYAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQ
. * . . * : .. * : *:
Mvan_5758|M.vanbaalenii_PYR-1 QVLIHGGAGGVGFLAVQLALARGAQVYATGSTSSQAVIRAAG--AVPIDY
MAV_5196|M.avium_104 TVAVSAAAGGVGSLVTQLLVLRKARVLGIAGPGNADWLRAHG--VVPIAY
MAB_0750|M.abscessus_ATCC_1997 TVAVSAAAGGVGTIAVQLARAAGATVIGIAGPDNDEWLTAHG--IIPVNY
MSMEG_6747|M.smegmatis_MC2_155 TLLVHAAAGGVGTFAVQLAGARGVSVIGTAGEGNHDYLRSIG--ATPVTY
Mb1489c|M.bovis_AF2122/97 TVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDY
Rv1454c|M.tuberculosis_H37Rv TVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDY
MUL_1855|M.ulcerans_Agy99 AILVHAGAGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGATEVLDY
Mflv_3686|M.gilvum_PYR-GCK AILVHAGAGGVGLLLTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDY
TH_3440|M.thermoresistible__bu TILVHAGAGGVGLILTQWATHLGARVITTVSTPQKAELSRKAGAAEVLDY
MMAR_1738|M.marinum_M AVLVHGGAGGVGALVVQLAAILGANVTATVRSDAGELVSRLGAQRVIDTR
MLBr_00118|M.leprae_Br4923 LLLLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINY
: : ..:.*:* * . * .
Mvan_5758|M.vanbaalenii_PYR-1 TAT------TVDEYVAAHTGGEGFDVVADNVGGATLDASFTAVKRYTGHV
MAV_5196|M.avium_104 GDG-------LTDRLREAAPDG-IDAFIDLFGPQYVQLAV-DLGVP----
MAB_0750|M.abscessus_ATCC_1997 GDG-------LAERITAAAPQGRVDAFLDLFGGGYVDLALNELGVD----
MSMEG_6747|M.smegmatis_MC2_155 GDG-------LLERVRAAAPQG-VDAVLDASGRGEIPLSI-ELTGD----
Mb1489c|M.bovis_AF2122/97 PED----AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLA
Rv1454c|M.tuberculosis_H37Rv PED----AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLA
MUL_1855|M.ulcerans_Agy99 PTD----AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLA
Mflv_3686|M.gilvum_PYR-GCK PSQDAGGAAAFGDRIRELTDGDGVAAVYDGVGASTFEASLASLAIRGTLA
TH_3440|M.thermoresistible__bu PTD----PEEFGARIRDLTGGEGVPVVYDGVGRSTFDASLASLAVRGTLA
MMAR_1738|M.marinum_M TEA-------------FERTATDFDVVIDTVGGDTLDRSFAVLRPGGR--
MLBr_00118|M.leprae_Br4923 RDE--------DFVARLQQQNGGADVILDIMGAAYLDRNIDALAIDGQLI
.. * * . . :
Mvan_5758|M.vanbaalenii_PYR-1 VSALGWG--THSLAPLSFRGAAYSGVFTLMPLLTGRGRDHH---GEIVAE
MAV_5196|M.avium_104 -------------PERIDTIISFEKAAEVGAKTEGSAEAST---PEVLAE
MAB_0750|M.abscessus_ATCC_1997 -------------LQRIDTIIDFAAIERYGVQSVGNAEGAS---AQVLSE
MSMEG_6747|M.smegmatis_MC2_155 -------------PQRVLTLVAFDQAGTGIQVHAGGAGDSL---SKALSD
Mb1489c|M.bovis_AF2122/97 LFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTR-TGEEF---SWRAAE
Rv1454c|M.tuberculosis_H37Rv LFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTR-TGEEF---SWRAAE
MUL_1855|M.ulcerans_Agy99 LFGAASGPVPPVEPQRLNAAGSVYLTRPSLFHFIR-TAEEF---SWRASE
Mflv_3686|M.gilvum_PYR-GCK LFGAASGPVPPIDPQRLNTAGSVFLTRPNLAHHTR-TPDEF---SWRAGE
TH_3440|M.thermoresistible__bu LFGAASGPVPPFDPQRLNAAGSVYLTRPSLVHFTR-TPDEF---GWRAGE
MMAR_1738|M.marinum_M -------------LVTLSAPPPAGKADEHGVTAMFFIVTPN---RDQLNR
MLBr_00118|M.leprae_Br4923 VIGLQGGVKGELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTAS
Mvan_5758|M.vanbaalenii_PYR-1 AAALADSGRLAPRLHPTTFPLDAVNDAHTAVE-SGSATGKVVVEPNV---
MAV_5196|M.avium_104 MADLIVSGALEFDIA-ATYPLDRVADAFAELE-QRHTHGKIVLLPTDSQ-
MAB_0750|M.abscessus_ATCC_1997 LAALIVDGKLEVTVA-QTFPLDEVRSAYELLE-RQHTRGKIVLVP-----
MSMEG_6747|M.smegmatis_MC2_155 VVALITDGRLTVPIS-ATYPLDEAAAALDASR-TGHATGKIVVVP-----
Mb1489c|M.bovis_AF2122/97 LFDAIGSEAITVAVG-GRYPLADALRAHQDLE-ARKTVGSVVLLP-----
Rv1454c|M.tuberculosis_H37Rv LFDAIGSEAITVAVG-GRYPLADALRAHQDLE-ARKTVGSVVLLP-----
MUL_1855|M.ulcerans_Agy99 LFDAISSGVITIEVG-GRYRLADAMKAHQDLE-ARKTIGSAVLLP-----
Mflv_3686|M.gilvum_PYR-GCK LLTAIADGALTVTVS-NRYALREAEQAHRDLQ-GRRTVGSVVLIP-----
TH_3440|M.thermoresistible__bu FLSAVADGTLTITVG-ERYPLAEAERAHRDLE-GRKTVGSVVLLP-----
MMAR_1738|M.marinum_M LGELVGSGRLHVEIA-QSFPLANGREAFESGRGAARRAGKTVITVGQ---
MLBr_00118|M.leprae_Br4923 IWPMIADGSVRPIIG-ARMAVQQAADAHQLLL-SGKVSGKIVLTVAGSGT
. : : : * *. *:
Mvan_5758|M.vanbaalenii_PYR-1 --------
MAV_5196|M.avium_104 --------
MAB_0750|M.abscessus_ATCC_1997 --------
MSMEG_6747|M.smegmatis_MC2_155 --------
Mb1489c|M.bovis_AF2122/97 --------
Rv1454c|M.tuberculosis_H37Rv --------
MUL_1855|M.ulcerans_Agy99 --------
Mflv_3686|M.gilvum_PYR-GCK --------
TH_3440|M.thermoresistible__bu --------
MMAR_1738|M.marinum_M --------
MLBr_00118|M.leprae_Br4923 ETLLSRHH