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HAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVG PGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKR GDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPEDAWQFAGRVRELTGGT GVQAVYDGVGATTFDASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSW RAAELFDAIGSEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1454c | qor | - | 100% (328) | PROBABLE QUINONE REDUCTASE QOR (NADPH:quinone reductase) (Zeta-crystallin homolog protein) |
| M. tuberculosis H37Rv | Rv3141 | fadB4 | 6e-33 | 34.63% (335) | NADPH quinone oxidoreductase |
| M. tuberculosis H37Rv | Rv3777 | - | 1e-32 | 30.35% (313) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1489c | qor | 0.0 | 100.00% (328) | quinone reductase |
| M. gilvum PYR-GCK | Mflv_3686 | - | 1e-125 | 68.07% (332) | alcohol dehydrogenase |
| M. leprae Br4923 | MLBr_00118 | - | 2e-29 | 30.93% (333) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_2757 | - | 1e-103 | 59.09% (330) | quinone reductase Qor |
| M. marinum M | MMAR_2259 | qor | 1e-158 | 84.19% (329) | quinone reductase Qor |
| M. avium 104 | MAV_3325 | - | 1e-138 | 75.91% (328) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3106 | - | 1e-134 | 72.42% (330) | quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_3440 | - | 1e-135 | 72.87% (328) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_1855 | qor | 1e-156 | 83.59% (329) | quinone reductase Qor |
| M. vanbaalenii PYR-1 | Mvan_2724 | - | 1e-130 | 71.34% (328) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1454c|M.tuberculosis_H37Rv -----------------------------------------------MHA
Mb1489c|M.bovis_AF2122/97 -----------------------------------------------MHA
MMAR_2259|M.marinum_M ----------------------------------------MVGHDSGVHA
MUL_1855|M.ulcerans_Agy99 ----------------------------------------MVGHDSGVHA
MAV_3325|M.avium_104 -----------------------------------------------MHA
Mflv_3686|M.gilvum_PYR-GCK --------------------------------------------MVDMYA
Mvan_2724|M.vanbaalenii_PYR-1 -----------------------------------------------MYA
TH_3440|M.thermoresistible__bu VQTAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKA
MSMEG_3106|M.smegmatis_MC2_155 -------------------------------MEHIRTGELHEWMIGGVHA
MAB_2757|M.abscessus_ATCC_1997 -----------------------------------------------MRA
MLBr_00118|M.leprae_Br4923 -----------------------------------------------MHA
: *
Rv1454c|M.tuberculosis_H37Rv IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
Mb1489c|M.bovis_AF2122/97 IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
MMAR_2259|M.marinum_M IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MUL_1855|M.ulcerans_Agy99 IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MAV_3325|M.avium_104 IEVSETGGPEVLRYVETPTPTAGPGQVLIKAEAIGVNYIDTYFRSGQYPR
Mflv_3686|M.gilvum_PYR-GCK IEVAETGGPEVLSFVETSRPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
Mvan_2724|M.vanbaalenii_PYR-1 IEVAETGGPEVLSFVERPQPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
TH_3440|M.thermoresistible__bu IEVRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
MSMEG_3106|M.smegmatis_MC2_155 IEVAETGGPEVLNYIERPEPSPGPGEVLIKADAIGVNFIDTYFRSGLYPR
MAB_2757|M.abscessus_ATCC_1997 IEVPVTGGPEVLTLVEKTDPAPGPGEVLIDVDAVGVNFRDIYLRNGSYTA
MLBr_00118|M.leprae_Br4923 IVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGKYPH
* . :. : : . .* *:::*.. * *** * * *.
Rv1454c|M.tuberculosis_H37Rv --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANGAYAEFC
Mb1489c|M.bovis_AF2122/97 --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANGAYAEFC
MMAR_2259|M.marinum_M --ELPFVIGSEVCGTVVALGPGATAADAGGIAVGDRVVSASANGGYAEFC
MUL_1855|M.ulcerans_Agy99 --ELPFVIGSEVCGTVVAVGPGATAADAGGIAVGDRVVSASANGGYAEFC
MAV_3325|M.avium_104 --ELPFIIGQELCGTVAAAGDGVD-----GFKVGDRVVSAAATGGYAEYA
Mflv_3686|M.gilvum_PYR-GCK --ETPFIAGSEVCGVIEEVGEDVA-----ALNVGDRVVTTQSQGAYAEYC
Mvan_2724|M.vanbaalenii_PYR-1 --EVPFVVGTEVCGVIEAVGEGVA-----ALKVGDRVVTDKSLGAYAEYC
TH_3440|M.thermoresistible__bu --EVPFIVGTEVCGTVEAVGDGVA-----ALRVGDRVLTDKANGAYAEYT
MSMEG_3106|M.smegmatis_MC2_155 --ELPFVVGTEVCGTVAAIGNDVA-----ALKVGDRVVTANAVGAYADYC
MAB_2757|M.abscessus_ATCC_1997 --PLPHIPGSEVSGVVRAVGEGVQ-----SLAPGDRVASPVAAWGYAEST
MLBr_00118|M.leprae_Br4923 PPGASAIIGMEVAGVVAAVSSGVT-----EWSVGQEVCALLAGGGYAEYV
. : * *:.*.: . .. *:.* : : .**:
Rv1454c|M.tuberculosis_H37Rv TAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAG
Mb1489c|M.bovis_AF2122/97 TAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAG
MMAR_2259|M.marinum_M TAPAALTAKVPDGVSAEVAASALLKGLTAHYLLKSVYPVADGDAILVHAG
MUL_1855|M.ulcerans_Agy99 TAPAALTAKVPDVVSAEVAASALLKGLTAHYLLKSVCPVADGDAILVHAG
MAV_3325|M.avium_104 TAPASLTAHVPDGVAADVAASALLKGLTAHYLLTSVYPVQAGDTVLVHAG
Mflv_3686|M.gilvum_PYR-GCK VAPADFVAYVPDAVAPEVAASALLKGMTAHYLLKSTYPVQQGDAILVHAG
Mvan_2724|M.vanbaalenii_PYR-1 LAPADFVAYVPDGVAPEVAASALLKGMTAHYLIKSTYPVQQGDVVLLHAG
TH_3440|M.thermoresistible__bu VAPADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHAG
MSMEG_3106|M.smegmatis_MC2_155 VAPADFVAYVPDGVAPEAVASALLKGMTAHYLLKSTYPVQPSDTVLVHAG
MAB_2757|M.abscessus_ATCC_1997 TAPADYTAKVPAGLSAEVAASSLLQGITTHYLLTSVYPVAAGDTVLVHAG
MLBr_00118|M.leprae_Br4923 AVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGG
.** . :* : *. . *. : . : .: :*:*.*
Rv1454c|M.tuberculosis_H37Rv AGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED----
Mb1489c|M.bovis_AF2122/97 AGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED----
MMAR_2259|M.marinum_M AGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGAAEVLDYPTD----
MUL_1855|M.ulcerans_Agy99 AGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGATEVLDYPTD----
MAV_3325|M.avium_104 AGGVGLILTQWAHLLGARVITTVSTPEKARRSAQAGANEVLSYPDD----
Mflv_3686|M.gilvum_PYR-GCK AGGVGLLLTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPSQDAGG
Mvan_2724|M.vanbaalenii_PYR-1 AGGVGLILTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPDD----
TH_3440|M.thermoresistible__bu AGGVGLILTQWATHLGARVITTVSTPQKAELSRKAGAAEVLDYPTD----
MSMEG_3106|M.smegmatis_MC2_155 AGGVGLILTQWATSLGTRVITTASTPEKAELSRQAGAVEVLDYPDPD--D
MAB_2757|M.abscessus_ATCC_1997 AGGMGLLLTQWATYRGVRVITTVSSEAKEKLSREAGAAEVLPYPDPAD--
MLBr_00118|M.leprae_Br4923 TSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDE----
:.*:* * * .. * *..: * . . ** .: *
Rv1454c|M.tuberculosis_H37Rv AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASG
Mb1489c|M.bovis_AF2122/97 AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASG
MMAR_2259|M.marinum_M AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAASG
MUL_1855|M.ulcerans_Agy99 AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAASG
MAV_3325|M.avium_104 ADEFGNRIRALTDGAGVAAVYDGVGASTFDASLASLAVRGTLALFGAASG
Mflv_3686|M.gilvum_PYR-GCK AAAFGDRIRELTDGDGVAAVYDGVGASTFEASLASLAIRGTLALFGAASG
Mvan_2724|M.vanbaalenii_PYR-1 PKAFGDRIRELTDGDGVAAVFDGVGASTFEASLASLAVRGTLALFGAASG
TH_3440|M.thermoresistible__bu PEEFGARIRDLTGGEGVPVVYDGVGRSTFDASLASLAVRGTLALFGAASG
MSMEG_3106|M.smegmatis_MC2_155 PQPFASRVRELTGGAGVAAVYDGVGATTFDASLASLAVRGTLALFGASSG
MAB_2757|M.abscessus_ATCC_1997 PSEFAAQIRELTAGEGVAVVYDGVGKSTFEASLAAVRVRGLIALYGAASG
MLBr_00118|M.leprae_Br4923 --DFVARLQQQNGG--ADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG
* ::: . * . .: * :* : :: .: :: : * : : * .*
Rv1454c|M.tuberculosis_H37Rv PVPPVDP-----QRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIG
Mb1489c|M.bovis_AF2122/97 PVPPVDP-----QRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIG
MMAR_2259|M.marinum_M PVPPVDP-----QRLNAAGSVYLTRPSLFHFIRTAEEFSWRASELFDAIS
MUL_1855|M.ulcerans_Agy99 PVPPVEP-----QRLNAAGSVYLTRPSLFHFIRTAEEFSWRASELFDAIS
MAV_3325|M.avium_104 PVPPFDP-----QRLNAAGSVFLTRPSLAHFIRTGQEFSWRAEELFAAIA
Mflv_3686|M.gilvum_PYR-GCK PVPPIDP-----QRLNTAGSVFLTRPNLAHHTRTPDEFSWRAGELLTAIA
Mvan_2724|M.vanbaalenii_PYR-1 PVPPVDP-----QRLNAAGSVYLTRPNLAHYTRTPDEFSWRAGELLTAIA
TH_3440|M.thermoresistible__bu PVPPFDP-----QRLNAAGSVYLTRPSLVHFTRTPDEFGWRAGEFLSAVA
MSMEG_3106|M.smegmatis_MC2_155 PVPPFDP-----QRLNAAGSVFLTRPTLAHHTRTADEFSWRAGELINAIA
MAB_2757|M.abscessus_ATCC_1997 QVPPFDP-----QRLTAK-SAVLTRPTMGHFIRTPEEFAWRADDVLDLVS
MLBr_00118|M.leprae_Br4923 VKGELNLGKVLSKRARIIGSTLRARPVNGPNSKS-EIVAAVTASIWPMIA
.: :* *. :** :: : .. : .. :.
Rv1454c|M.tuberculosis_H37Rv SEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP-------------
Mb1489c|M.bovis_AF2122/97 SEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP-------------
MMAR_2259|M.marinum_M SGVITIEVGGRYRLADAMKAHQDLEARKTIGSVVLLP-------------
MUL_1855|M.ulcerans_Agy99 SGVITIEVGGRYRLADAMKAHQDLEARKTIGSAVLLP-------------
MAV_3325|M.avium_104 AGDITVEVGGRYPLADAARAHRDLQGRKTTGSIVLLP-------------
Mflv_3686|M.gilvum_PYR-GCK DGALTVTVSNRYALREAEQAHRDLQGRRTVGSVVLIP-------------
Mvan_2724|M.vanbaalenii_PYR-1 DGTLDVTVSHRYALRDAEQAHRDLQGRKTVGSVVLLP-------------
TH_3440|M.thermoresistible__bu DGTLTITVGERYPLAEAERAHRDLEGRKTVGSVVLLP-------------
MSMEG_3106|M.smegmatis_MC2_155 DGSIKITVGGTYPLAEASRAHTDLQGRKTVGSIVLIP-------------
MAB_2757|M.abscessus_ATCC_1997 RGTLKITIGAGYPLEQAAQAHTDLEARKTTGSVVLVP-------------
MLBr_00118|M.leprae_Br4923 DGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
: :. : :* ** * . :. *. **