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M. smegmatis MC2 155 MSMEG_2043 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 2121141 - 2121749
length: 202

MKAEASPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYANLTMAAVAERAQTTKTALYRRWSSKAELVH
EAVFPAVPTGLVAPAGDIAADVHAMIAAARDVFTSPVVRAALPGLIADVSADANLNARVMERFTGVFAAV
RERIVDGIARGEVHAAVSPDRLVEIIGGATMLRLLLVSDENLDDEWVHQTAAIVIHGVTVGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2043--100% (202)transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_4983-5e-2243.07% (137) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3410-3e-1832.11% (190) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3192c-2e-7671.21% (198) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4496-2e-7065.67% (201) TetR family transcriptional regulator
M. tuberculosis H37RvRv3167c-2e-7671.21% (198) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0260-1e-1834.41% (186) transcriptional regulator TetR
M. marinum MMMAR_1394-7e-7567.84% (199) TetR family transcriptional regulator
M. avium 104MAV_4057-8e-7670.20% (198) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0688-6e-5451.76% (199) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_2482-1e-7467.34% (199) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1870-7e-7269.19% (198) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb3192c|M.bovis_AF2122/97           MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAER
Rv3167c|M.tuberculosis_H37Rv        MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAER
MAV_4057|M.avium_104                MKADPSGLDKAPGAGRPRDPRIDSAILSATAELLVQTGYSNISLAAVAER
MMAR_1394|M.marinum_M               MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLAAVAER
MUL_2482|M.ulcerans_Agy99           MKADPSSLDKAPGAGRPRDPRIDFAILSATMELLVQIGYSNLSLAAVAER
MSMEG_2043|M.smegmatis_MC2_155      MKAEASPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYANLTMAAVAER
Mflv_4496|M.gilvum_PYR-GCK          MKTDSSAGGKATGAGRPRDPRIDAAILAATADLLVEIGYSNVTMAAVAER
Mvan_1870|M.vanbaalenii_PYR-1       MNTDPSPGDKTPGAGRPRDPRIDAAILRATADLLVEIGYSNVTMAAVAER
TH_0688|M.thermoresistible__bu      MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNLTMSAVAER
MAB_0260|M.abscessus_ATCC_1997      MSTEESS----LGRGRRRSSDIDVKALAAARELLVEQGWEATTMVAIADR
                                    *.:: .      * ** *.. **   * *: :***: *:   :: *:*:*

Mb3192c|M.bovis_AF2122/97           AGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAADIRMMIAAT
Rv3167c|M.tuberculosis_H37Rv        AGTTKSALYRRWSSKAELVHEAAFP-AAPTALQAAAGDIAADIRMMIAAT
MAV_4057|M.avium_104                AGTTKSALYRRWSSKAELVHEAAFP-TAPTALEAPAGDIAADMRMMIEAT
MMAR_1394|M.marinum_M               AGTTKSALYRRWSSKAELVHEAAFP-VTPSALSAPAGDFAGDIRMMVAAT
MUL_2482|M.ulcerans_Agy99           AGTTKSALYRRWSSKAELVHEAAFP-VTPSALSAPAGDFAGDIRMMVAAT
MSMEG_2043|M.smegmatis_MC2_155      AQTTKTALYRRWSSKAELVHEAVFP-AVPTGLVAPAGDIAADVHAMIAAA
Mflv_4496|M.gilvum_PYR-GCK          AGTTKTALYRRWSSKAELVHEAAFP-VTPTAIQSPPGDIAADLRAMIEVT
Mvan_1870|M.vanbaalenii_PYR-1       AGTTKTALYRRWSSKAELVHEAAFP-VTPTAIQTPPGDIAADLRAMIEAA
TH_0688|M.thermoresistible__bu      AGTTKTALYRRWSSKPELVYAATAP-TDPVDTVESSDDVAGIVRALIERN
MAB_0260|M.abscessus_ATCC_1997      ASVGKPALYRRWPSRAHLVFEAVFGWTAPTPEMSAAAGVTDWVRQSCSYT
                                    * . *.******.*:..**. *.   . *     .. ..:  ::      

Mb3192c|M.bovis_AF2122/97           RDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAAVRMRLREAVD
Rv3167c|M.tuberculosis_H37Rv        RDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAAVRMRLREAVD
MAV_4057|M.avium_104                RDVFTTPVVRAALPGLVADMTADPALNARVMSRFADLFTAVRVRLGEAVD
MMAR_1394|M.marinum_M               RDVFTTPVVRAALPGLVADMTADADLNARVLSRFTELFATVRIRLQEAVD
MUL_2482|M.ulcerans_Agy99           RDVFTTPVVRAALPGLVADMTAEADLNARVLSRFTELFATVRIRLQEAVD
MSMEG_2043|M.smegmatis_MC2_155      RDVFTSPVVRAALPGLIADVSADANLNARVMERFTGVFAAVRERIVDGIA
Mflv_4496|M.gilvum_PYR-GCK          RDVFLSPVVRAALPGLIADMSANADLTGRIGARFTDLFAAVRARLQDAVE
Mvan_1870|M.vanbaalenii_PYR-1       RDVFTSPVVRSALPGLIADLSADADLAGRVGARFTDLFAAVRNRLHDAVE
TH_0688|M.thermoresistible__bu      RQITATPAARAAMPGLLVDMAADPRLHRGLLGRVGSLVEALRRRLAEAAG
MAB_0260|M.abscessus_ATCC_1997      AELFERPDVIAAAPALLGQMRTDPELGQALWGSFGATGAGLLSRVMRAQQ
                                     ::   * . :* *.*: :: ::. *   :   .      :  *:  .  

Mb3192c|M.bovis_AF2122/97           R--GEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWVDQTTAIVVRG
Rv3167c|M.tuberculosis_H37Rv        R--GEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWVDQTTAIVVRG
MAV_4057|M.avium_104                R--GEAHPDVDPDRLIELIGGATMLRMLLRPEEELDDAWVEQTTAIVVHG
MMAR_1394|M.marinum_M               R--GEAHPDVDPNRMIELIGGATMLRVLLYPDQMLDEAWVDQTTAILVHG
MUL_2482|M.ulcerans_Agy99           R--GEAHPDVDPNRMIELIGGATMLRVLLYPDQMLDEAWVDQTTAILVHG
MSMEG_2043|M.smegmatis_MC2_155      R--GEVHAAVSPDRLVEIIGGATMLRLLLVSDENLDDEWVHQTAAIVIHG
Mflv_4496|M.gilvum_PYR-GCK          R--GEVRESVDPDRLVSLVGGATLLALLQTPDALASPSWVDSTTDILLRG
Mvan_1870|M.vanbaalenii_PYR-1       R--GEVRAGVDPDQLVNLIGGATLLALLQAPDDLTAPAWVDRTTDILLHG
TH_0688|M.thermoresistible__bu      R--GEVQSGVDADRLTELIGGSVMFRMVLHPDEPITERWADEVAAILIRG
MAB_0260|M.abscessus_ATCC_1997      PEIGQEEAQERANAIMFMIIGANMLARQLLPGEHAEAVIKHLPELLTEPG
                                       *: .    .: :  :: *: ::     .         .    :   *

Mb3192c|M.bovis_AF2122/97           VHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv        VHRAAPGGSVV
MAV_4057|M.avium_104                VRR--------
MMAR_1394|M.marinum_M               VTR--------
MUL_2482|M.ulcerans_Agy99           VTR--------
MSMEG_2043|M.smegmatis_MC2_155      VTVGR------
Mflv_4496|M.gilvum_PYR-GCK          VVAGA------
Mvan_1870|M.vanbaalenii_PYR-1       VMA--------
TH_0688|M.thermoresistible__bu      VTKEG------
MAB_0260|M.abscessus_ATCC_1997      ESPGSVRPSG-