For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NEALPAGAGADTSTRHRILVATAEVLARSGQTKLSLSEVALQAGVSRPTLYRWFADKQELLEAFGNYERE MFDNGIGRATAGLRGNEKLDAALRFIVQYQQSYSGVRLVDIEPEVVIAQLAHVIPIMRARLLKLLSGPNA AVKAATAIRVAISHYIVRSDDADQFLAQLRHAVGIRQTDTN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2553 | - | - | 100% (182) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2557 | - | 7e-54 | 59.32% (177) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2309 | - | 3e-07 | 34.31% (102) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3076c | - | 5e-06 | 32.35% (102) | AsnC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4118 | - | 7e-74 | 81.07% (169) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3050c | - | 5e-06 | 32.35% (102) | AsnC family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 8e-06 | 34.31% (102) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2046 | - | 6e-08 | 39.76% (83) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0389 | - | 4e-69 | 77.71% (166) | putative regulatory protein |
| M. avium 104 | MAV_5134 | - | 4e-66 | 73.96% (169) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0275 | - | 2e-73 | 81.93% (166) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1039 | - | 9e-69 | 77.11% (166) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2227 | - | 3e-77 | 82.02% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4118|M.gilvum_PYR-GCK -------------------------------------------MNQPADD
Mvan_2227|M.vanbaalenii_PYR-1 -------------------------------------------MNEPASD
MSMEG_2553|M.smegmatis_MC2_155 -------------------------------------------MNEALP-
TH_0275|M.thermoresistible__bu -------------------------------------------VNQPTDQ
MMAR_0389|M.marinum_M -------------------------------------------MSQAFGA
MUL_1039|M.ulcerans_Agy99 -------------------------------------------MSQAFGA
MAV_5134|M.avium_104 -------------------------------------------MSHPVRA
Mb3076c|M.bovis_AF2122/97 -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAB_2046|M.abscessus_ATCC_1997 ---------------------------------------------MPTEP
Mflv_4118|M.gilvum_PYR-GCK AQTPDD-VSTRQRILAATAEVLGRSGQTKLSLSEVALQAGVSRPTLYRWF
Mvan_2227|M.vanbaalenii_PYR-1 AAAAED-TSTRHRILVATAEVLSRSGQTKLSLSEVALQAGVSRPTLYRWF
MSMEG_2553|M.smegmatis_MC2_155 AGAGAD-TSTRHRILVATAEVLARSGQTKLSLSEVALQAGVSRPTLYRWF
TH_0275|M.thermoresistible__bu QAAPEEEASTRHRILEATAEVLSRAGKRKLSLSEVALQAGVSRPTLYRWF
MMAR_0389|M.marinum_M IDTTDGDTSTRQRILAATAEVLARSGKTKLSLSEVAAQAGVSRPTLYRWF
MUL_1039|M.ulcerans_Agy99 IDTTDGDTSMRQRILAATAEVLARSGKTKLSLSEVAAQAGVSRPTLYRWF
MAV_5134|M.avium_104 TAIADTDTSTRQRILAATAEVLGRNGKTKLSLSDVATQAGVSRPTLYRWF
Mb3076c|M.bovis_AF2122/97 ERWREHRKKVRNEIVDAAFRAIDRLG-PELSVRQIAEEAGTAKPKIYRHF
Rv3050c|M.tuberculosis_H37Rv ERWREHRKKVRNEIVDAAFRAIDRLG-PELSVRQIAEEAGTAKPKIYRHF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
MAB_2046|M.abscessus_ATCC_1997 VRVSFR-RHVREKVLRATRELAIEKGWDQVRMSEVAESVGVSRPTLYKEF
* .:: *: . . * :: : ::* ..*.::*.:*: *
Mflv_4118|M.gilvum_PYR-GCK ADKQALLEAFGVHEREMFETGILKATAGLRG----------------TER
Mvan_2227|M.vanbaalenii_PYR-1 ADKPALLEAFGIYEREMFETGIAKATAGLRG----------------NDR
MSMEG_2553|M.smegmatis_MC2_155 ADKQELLEAFGNYEREMFDNGIGRATAGLRG----------------NEK
TH_0275|M.thermoresistible__bu ASKEDLLDAFGAYERQLFDTGISKATAGLRG----------------NEK
MMAR_0389|M.marinum_M ASKEELLATFSRYERQVFESGLSKATAGLKG----------------VDK
MUL_1039|M.ulcerans_Agy99 ASKEELLATFSRYERQVFESGLSKATAGLKG----------------VDK
MAV_5134|M.avium_104 ASKEELLSAFSAYERQIFESGLVKATAGLKG----------------VDK
Mb3076c|M.bovis_AF2122/97 TDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQ
Rv3050c|M.tuberculosis_H37Rv TDKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQ
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDK
MAB_2046|M.abscessus_ATCC_1997 GDKQGLGDALVVSEGQRFMEGILAVLAEHVGDVRGGITAAVQFTLCEAED
.* * :: : : .: . :
Mflv_4118|M.gilvum_PYR-GCK VDAAMRFIVEY-----QQSYSG---VRLVDIEPEVVISRLAHIIPLMRAQ
Mvan_2227|M.vanbaalenii_PYR-1 VDAAMRFIVDY-----QQSYSG---VRLVDIEPEVVIGRLAHIIPAMRAQ
MSMEG_2553|M.smegmatis_MC2_155 LDAALRFIVQY-----QQSYSG---VRLVDIEPEVVIAQLAHVIPIMRAR
TH_0275|M.thermoresistible__bu LDAALRFIVEY-----QHSYSG---VRLVDIEPEVVIAQLSQVIPVMRAR
MMAR_0389|M.marinum_M LDAALRFIVDY-----QYSYSG---VRMVDIEPELVISQMSGVIPEMREG
MUL_1039|M.ulcerans_Agy99 LDAALRFIVDY-----QYSYSG---VRMVDIEPELVISQMSSVIPEMREG
MAV_5134|M.avium_104 LDAVLRFIVDY-----QHSYSG---VRMVDVEPEHTIAQFSWVIPQMREG
Mb3076c|M.bovis_AF2122/97 HPNVLRVFIQG-----RSAKQSEATVRTLNEGREITLAMAEMFNNELREM
Rv3050c|M.tuberculosis_H37Rv HPNVLRVFIQG-----RSAKQSEATVRTLNEGREITLAMAEMFNNELREM
MLBr_01733|M.leprae_Br4923 HPNVLRVFIQG-----RFSAQSEATVRTLDEGREITLTMAEMFNNELREM
MAB_2046|M.abscessus_ATCC_1997 SPLLKAVLTSNPSGNDRGGSSSTGVLPLLPTSASLLQLCSAALITWFNDH
.: . : . .. : : . . :.
Mflv_4118|M.gilvum_PYR-GCK LEKLLPGANGAVKAATAVRVAVCHYIVRADDD------DQFLAQLR----
Mvan_2227|M.vanbaalenii_PYR-1 LEKLLPGPNGAVKAATAIRVAVSHYIVRADDD------DQFLAQLR----
MSMEG_2553|M.smegmatis_MC2_155 LLKLLSGPNAAVKAATAIRVAISHYIVRSDDA------DQFLAQLR----
TH_0275|M.thermoresistible__bu LQRLLPGANGAVKAATAIRVAVSHYIVRSDDD------DQFLAQLR----
MMAR_0389|M.marinum_M LQRLLPGPNAAVKAATAIRIAISHYIVRSDDA------DQFLAQLR----
MUL_1039|M.ulcerans_Agy99 LQRLLPGPNAAVKAATAIRIAISHYIVRSDDA------DQFLAQLR----
MAV_5134|M.avium_104 LQRHLPGPNAAVKAATVIRIAISHYIVRSDDA------DQFLAQLR----
Mb3076c|M.bovis_AF2122/97 ELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMM
Rv3050c|M.tuberculosis_H37Rv ELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMM
MLBr_01733|M.leprae_Br4923 ELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMM
MAB_2046|M.abscessus_ATCC_1997 FDDLDP-EDVEEVADVLVRLTVSHVVLPAADIAT---TGERISRVA----
. * : : * : ::::
Mflv_4118|M.gilvum_PYR-GCK -------HAVGLRATD---------------
Mvan_2227|M.vanbaalenii_PYR-1 -------HSVGIKPS----------------
MSMEG_2553|M.smegmatis_MC2_155 -------HAVGIRQTDTN-------------
TH_0275|M.thermoresistible__bu -------HAVGIKAPAGEPAPAR--------
MMAR_0389|M.marinum_M -------HAVGLKGG----------------
MUL_1039|M.ulcerans_Agy99 -------HAVGLKGG----------------
MAV_5134|M.avium_104 -------HAVGIKAPTD--------------
Mb3076c|M.bovis_AF2122/97 GVIVGTAEALGIAVDPDQPIHDAVPNNPAVR
Rv3050c|M.tuberculosis_H37Rv GVIVGTAEALGIAVDPDQPIHDAVPNNPAVR
MLBr_01733|M.leprae_Br4923 AVIVGTAETLGISMNPDRPIHDAVPLDRSAS
MAB_2046|M.abscessus_ATCC_1997 ------LRYLGVVHSL---------------
. :*: