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SDIAARRQALRDRFPVWRPRTLADWLDDCARTYGSRPFVLCDHGALSYRQVAEESRRLAAGLRELGIGAG DRVGMLLANSLEFVTVKFAIARLGAIAVPFNYLYRRDELAFVLGDSGCRVLVTMTGFGSLDYQRMLDDIA PGWDTAGFAARHPAADELPSLRHVVLAEAEQPARQGLPLVANLGATAARLDVPPECVDPLGPADLLYTSG TTGSPKGVLLTHDSVLRTAYASALTRAYADGRRIVYALPCYHMFGYIEGLLSAMFVGGAAIMQQKFTAEG YFRAIDAHRATDMLCVPTMAVAMVESPARARYDLSSLTAILCGSAPAPVWLWQRIAKDFGVSEIVTGYGM TECGGCMSLTLPEDPLALASSTVGRPKLAGAAGVAGVDALVIYRVVDPDSGEELPPGTPGELLSTGPTAM IGYWNRPAETADALRDGWLHSGDLGLVRADGYLELTGRRKELYKSGGELVMPKEIEDLLAGHGDISQVFA VGLSDDRWGEIGCVVVVRAPGATITEDDVLALCRDKLARFKVPKRVVFYRSEDLPTTPTGKVQKFRLAEQ LRSADAVTGAERLPAGTS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5076 | - | - | 100% (579) | acyl-CoA ligase |
| M. avium 104 | MAV_2610 | - | 3e-67 | 33.27% (568) | acyl-CoA synthase |
| M. avium 104 | MAV_0600 | fadD | 5e-67 | 33.03% (548) | acyl-CoA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2533c | fadD35 | 2e-73 | 33.91% (519) | AMP-binding domain protein |
| M. gilvum PYR-GCK | Mflv_4867 | - | 5e-76 | 33.64% (535) | acyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv2505c | fadD35 | 3e-73 | 33.91% (519) | AMP-binding domain protein |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 1e-48 | 28.76% (532) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4377c | - | 1e-75 | 35.26% (519) | AMP-binding domain protein |
| M. marinum M | MMAR_3852 | fadD35 | 2e-75 | 35.00% (520) | fatty-acid-CoA ligase FadD35 |
| M. smegmatis MC2 155 | MSMEG_5649 | - | 3e-75 | 33.65% (523) | acyl-CoA synthetase |
| M. thermoresistible (build 8) | TH_2544 | - | 0.0 | 70.34% (563) | PUTATIVE acyl-CoA ligase |
| M. ulcerans Agy99 | MUL_4126 | fadD3 | 8e-67 | 32.97% (546) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4008 | - | 7e-75 | 35.42% (528) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 MITGITLSDALARHAAVRPHACALADPRRHTTFGELDERVTRLASALAAR
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 GVRSGDRVAVLGLNSIELVESWLAAHRLGAIAVPVNFRLAAGEIGYVLSD
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 SAATAIVVDVALESMVVQVRQQVPALHTVVTIGGNLEQTIAAADPDLPQC
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 AVADDAPAFIMYTSGTTGFPKGAVLTHRNLYLHAFSSIATLGHRSDDDCW
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 MAVAPLFHTAGVSGMLPMFLTGGKTVIPPSGGFDPDATIAAVVDEQVTSC
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 WMTPAQWQSVCALPGLAAHDLSRLRRVWWGAAPASTTLLRTMIDTFTGAE
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 IIAAFGQTECSPITCLLRGEDAIAKIGSVGTPMLNVEVRVVDDEMNDVDR
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 GEVGEIVYLGPLVMKEYWNKAAETAEAFRGGWFHSGDLVRQDADGYFYVV
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu --------------------------------------------------
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 DRKKDMIISGGENIYSAEVENVVATHPLVAEVAVIGVPHPKWGETPVAVI
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 --------------------------------------------------
Rv2505c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3852|M.marinum_M --------------------------------------------------
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 --------------------------------------------------
MAV_5076|M.avium_104 --------------------------------------------------
TH_2544|M.thermoresistible__bu ------------------------------------------------MR
MSMEG_5649|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4008|M.vanbaalenii_PYR-1 VPREPTDPPTDAEIEAHCRAQLASYKRPKYVTLVDVLPRNAAGKVLKGRL
Mflv_4867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_4377c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2533c|M.bovis_AF2122/97 ----------------------------------------------MAAA
Rv2505c|M.tuberculosis_H37Rv ----------------------------------------------MAAA
MMAR_3852|M.marinum_M ----------------------------------------------MATT
MUL_4126|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02546|M.leprae_Br4923 ----------------------------------------MTKLRHYLER
MAV_5076|M.avium_104 -MSDIAARRQALRDRFPVWRPRTLADWLDDCARTYGSR--PFVLCD----
TH_2544|M.thermoresistible__bu THDDIHRRRATLAARFPVWRPTTLGGWLDDCARRYAER--PFVITD----
MSMEG_5649|M.smegmatis_MC2_155 ------MKSYDAGPTGAPVLEETIGANFERIAATYPEHEALVEVAT----
Mvan_4008|M.vanbaalenii_PYR-1 RDEHATLISYSAGPTDAALLDETIGTNFERTVSRYPDNEALVDVPS----
Mflv_4867|M.gilvum_PYR-GCK -----MTGSYDAGPTDVAILEETIGANFARIARTHPGRDALVDVAG----
MAB_4377c|M.abscessus_ATCC_199 ------MKAYDAGATLSPIIEETIGENFERIARAHPDVGALVDVSG----
Mb2533c|M.bovis_AF2122/97 EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVA----
Rv2505c|M.tuberculosis_H37Rv EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVA----
MMAR_3852|M.marinum_M AAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVRS----
MUL_4126|M.ulcerans_Agy99 ----------------MTSDPRTVPTALDRLVRRLPNHDALVTD------
MLBr_02546|M.leprae_Br4923 GAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAMLPAMPARRSP
:
MAV_5076|M.avium_104 --------HGALSYRQVAEESRRLAAGLRELGIGAGDRVGMLLANSLEFV
TH_2544|M.thermoresistible__bu --------DITLSYRDVAERSRGLAAGLSALGVRRGDRVGLLMANYPEFV
MSMEG_5649|M.smegmatis_MC2_155 --------GRRWTYAELNDEIDATARGLMALGVDKGDRVGIWAPNCAEWI
Mvan_4008|M.vanbaalenii_PYR-1 --------GRRWTYAELNAEIDSLARALMAIGIEKGDRVGIWAPNCPEWT
Mflv_4867|M.gilvum_PYR-GCK --------GRRWTYAELDAEIDTVARGLMAIGVERGDRVGIWAPNCPEWV
MAB_4377c|M.abscessus_ATCC_199 --------DRRWTYRELDAEINRVARGLMSLGVAAGDRVGIWAPNCAEWV
Mb2533c|M.bovis_AF2122/97 --------RRRFNYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWV
Rv2505c|M.tuberculosis_H37Rv --------RRRFNYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWV
MMAR_3852|M.marinum_M --------GRRWSYAQLLTDVRQLATGLVRAGIGRGDRVGIWAPNRWEWV
MUL_4126|M.ulcerans_Agy99 --------ERSFTVSELNDEVYRAAAALIELGVKPAARVGIWSPNTWHWV
MLBr_02546|M.leprae_Br4923 HRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGIAILARNHRWFV
. :: * .* *: . :.: * :
MAV_5076|M.avium_104 TVKFAIARLGAIAVPFNYLYRRDELAFVLGDSGCRVLVTMTGFGSLDYQR
TH_2544|M.thermoresistible__bu TLKFAIARLGAIAVPFNYLYRSDELRFVLADSGCRVLITMTRFGQQDYQR
MSMEG_5649|M.smegmatis_MC2_155 MTQFAAAKVGAILVNINPAYRTHEVAYVLRQSGVRTLVSASSFKTSDYAS
Mvan_4008|M.vanbaalenii_PYR-1 MLQYATAKIGAILVTINPAYRTHELAYVLRHSAVRLLVSATEFKTSDYRA
Mflv_4867|M.gilvum_PYR-GCK IVQYATAKIGAILVNINPAYRTHELRYVLEQSGVATLISATQFKTSDYVA
MAB_4377c|M.abscessus_ATCC_199 LVQYATAKIGAILVNINPAYRTHELAYALNQSGVRTLICAKAFKSSDYVA
Mb2533c|M.bovis_AF2122/97 LVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAA
Rv2505c|M.tuberculosis_H37Rv LVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAA
MMAR_3852|M.marinum_M LVQYATAEIGAVLVTINPAYQARELEYALRQSGVAMVIAASGFKGSDYAA
MUL_4126|M.ulcerans_Agy99 VACLAIHHVGAAMVPLNTRYTADEAADILARTEAPVLFAMGHFLGSDRVA
MLBr_02546|M.leprae_Br4923 IANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIYDD-----EYTK
. .:** : :* : : :. :
MAV_5076|M.avium_104 MLDDIAPGWDTAGFAAR-HPAADELPSLRHVVLAEAE-QPARQGLPLVAN
TH_2544|M.thermoresistible__bu MLDEIVPGWDRDPFPSRPGSAAGTVGELRHVVLRGTDGEPPRPGRMTVTE
MSMEG_5649|M.smegmatis_MC2_155 MIAEVRP----------------ECPDLLDVVFLDND------DWDRL--
Mvan_4008|M.vanbaalenii_PYR-1 MVAEVRP----------------ELPGLAEVLFLATE------DWARLGE
Mflv_4867|M.gilvum_PYR-GCK MVDEVRP----------------DVPALQRVLFIGTA------DWDTLRA
MAB_4377c|M.abscessus_ATCC_199 MASQVMP----------------DAPGLRDVVFIGTS------DWTELVA
Mb2533c|M.bovis_AF2122/97 MLAEVGP----------------RCPDLADVILLESD------RWDAL--
Rv2505c|M.tuberculosis_H37Rv MLAEVGP----------------RCPDLADVILLESD------RWDAL--
MMAR_3852|M.marinum_M ILAEVAP----------------GCPELHDVAFLDGD------GWAKL--
MUL_4126|M.ulcerans_Agy99 GLDRKAL----------------PALRHIVRIPIEEP------DGTWDEF
MLBr_02546|M.leprae_Br4923 VVSKAEP----------------ALGKLRALGVNPDE-----EEPPGSTD
MAV_5076|M.avium_104 LGAT--AARLDVPPECVDPLGPADLLYTSGTTGSPKGVLLTHDSVLRTAY
TH_2544|M.thermoresistible__bu LEATGDPAALAAAAGDIDPQAAADLLYTSGTTGFPKGVVTSHDAVLRTAY
MSMEG_5649|M.smegmatis_MC2_155 RANQVDDAAFHERMATLANTDPINIQYTSGTTGFPKGATLSHRNILNNGF
Mvan_4008|M.vanbaalenii_PYR-1 RADLVSEDELRCRVRSLTPGDAINIQYTSGTTGSPKGATLSHRNILNNGY
Mflv_4867|M.gilvum_PYR-GCK AGSGVDDADLRRRSGALSNRDPINIQYTSGTTGFPKGATLSHRNILNNGF
MAB_4377c|M.abscessus_ATCC_199 GAERVTETALRARMSQLSNTDPINIQYTSGTTGYPKGATLSHRNVLNNGF
Mb2533c|M.bovis_AF2122/97 AGAEPDLPALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGY
Rv2505c|M.tuberculosis_H37Rv AGAEPDLPALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGY
MMAR_3852|M.marinum_M AGSGADLVALQEIATTLSADDPINIQYTSGTTGFPKGVTLSHRNILNNGY
MUL_4126|M.ulcerans_Agy99 IETGTDTGAVTARAAAVSPDDVSDILFTSGTTGRSKGVLCAHRQSLSASA
MLBr_02546|M.leprae_Br4923 ETLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLG
: *****. .**. *
MAV_5076|M.avium_104 ASALTRAYADGRRIVYALPCYHMFGYIEGLLSAMFVG-GAAIMQQKFTAE
TH_2544|M.thermoresistible__bu ASALTRAFEDGRRILFSLPCYHMFGYIEGLLSVMFAG-GAIIPQPTFSPE
MSMEG_5649|M.smegmatis_MC2_155 FVTELIALGPDDRLCIVPPFYHCFGMVMGTLGAVSHGTTIVIPAPGFDPG
Mvan_4008|M.vanbaalenii_PYR-1 FVTDLIDFGPGDRLCIPVPFYHCFGMVMGNLGCTTHGATMVIPAAGFDPA
Mflv_4867|M.gilvum_PYR-GCK FVTEQIRLQPGDRLCIPVPFYHCFGMVMGNLGCTTHGATIVIPAPAFDPG
MAB_4377c|M.abscessus_ATCC_199 FVAESIQLQAGDRLCIPVPFYHCFGMVMGNLGCTTHGATIVMPAPGFDPG
Mb2533c|M.bovis_AF2122/97 LVGELLGYTAQDRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAPGFDPA
Rv2505c|M.tuberculosis_H37Rv LVGELLGYTAQDRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAPGFDPA
MMAR_3852|M.marinum_M LVGELLEYTAEDRICIPVPFYHCFGMVMGNLAATSHGACMVIPAPGFDPA
MUL_4126|M.ulcerans_Agy99 SWAANGKITADDRHLCINPFFHNFGYKAGILACLQTG-ATLFPHLTFDPL
MLBr_02546|M.leprae_Br4923 GILSKVPFRAHEVTLLPAPMFHALGYLHATLAMFLGS--TLVLRRRFKPA
* :* :* . *. . . * .
MAV_5076|M.avium_104 GYFRAIDAHRATDMLCVPTMAVAMVESPA--RARYDLSSLTAILCGSAPA
TH_2544|M.thermoresistible__bu GYFAGIARHRATDVLCVPTMAVAMAESAH--REDHDLDSLRAMLCGSAPA
MSMEG_5649|M.smegmatis_MC2_155 ITLSAVESEKCTGLYGVPTMFIAMLGHPD--FANFDLSSLRTGIMAGSVC
Mvan_4008|M.vanbaalenii_PYR-1 ATLAAIEKEHCTAVYGVPTMFIAMLGHPD--LADCDVTSLRTGIMAGSPC
Mflv_4867|M.gilvum_PYR-GCK LTLRAIETERCTAVYGVPTMFIAMQNHPD--FAERDLSTLRTGIMAGAVC
MAB_4377c|M.abscessus_ATCC_199 RTLEAIERERCVGVYGVPTMFIAMLADPG--FAHRDLSTLRTGIMAGSVC
Mb2533c|M.bovis_AF2122/97 ATLRAVQDERCTSLYGVPTMFIAELGLPD--FTDYELGSLRTGIMAGAAC
Rv2505c|M.tuberculosis_H37Rv ATLRAVQDERCTSLYGVPTMFIAELGLPD--FTDYELGSLRTGIMAGAAC
MMAR_3852|M.marinum_M ATLRAVQAERCTSLYGVPTMFIAELGLAD--FATYDLSSLRTGIMAGSTC
MUL_4126|M.ulcerans_Agy99 RTLQAIERHRITVLPGPPTIYQTLLDHPA--RDDYDLSSLRFAVTGAATV
MLBr_02546|M.leprae_Br4923 TVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQL
: : .: . : *.: :: :* . ..:
MAV_5076|M.avium_104 PVWLWQRIAKDFGVSEIVTGYGMTECGGCMSLTLPEDPLALASSTVGRPK
TH_2544|M.thermoresistible__bu PAWLWRQIERDFGVSEIVTGYGMTECGGAMTLTLPEDPLELTSETVGRPK
MSMEG_5649|M.smegmatis_MC2_155 PIEVMKRVVADMHMAEVAICYGMTETSPVSCQTLIDDDLDRRTATIGR--
Mvan_4008|M.vanbaalenii_PYR-1 PVEVMKRCVNELKMSEVGIAYGMTETSPVSCQTRIEDDLDRRTATVGR--
Mflv_4867|M.gilvum_PYR-GCK PVEVMKRCVEEMHLTEMSIAYGMTETSPVSCQTLIDDDLERRTSTIGR--
MAB_4377c|M.abscessus_ATCC_199 PVEVMKRCIDEMHMAGVAIAYGMTETSPVSCQTLFDDDLDRRTATVGR--
Mb2533c|M.bovis_AF2122/97 PVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGR--
Rv2505c|M.tuberculosis_H37Rv PVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGR--
MMAR_3852|M.marinum_M PVEVMRKVIDQMHMAGISICYGMTETSPVATQTRSNDSLQRRVTTVGR--
MUL_4126|M.ulcerans_Agy99 PVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRADDDALTVATTCGR--
MLBr_02546|M.leprae_Br4923 GAELATRALEELGP-VIYNMYGSTEIAFATIAG--PKDLQINSATVGP--
: : : : ** ** . * *
MAV_5076|M.avium_104 LAGAAGVAGVDALVIYRVVDPDSGEELPPGTPGELLSTGPTAMIGYWNRP
TH_2544|M.thermoresistible__bu LAGAAGVDETGALTVYRTVDPGSGRELDAGATGELVSRGPTTMLGYWNRP
MSMEG_5649|M.smegmatis_MC2_155 ---------AHPHVEIKIIDPDTGETVERGQPGEFCTRGYSVMLGYWNDD
Mvan_4008|M.vanbaalenii_PYR-1 ---------AHPHVEIKIVDPDTGEIVKRGTAGEFCTRGYSVMLGYWGDE
Mflv_4867|M.gilvum_PYR-GCK ---------VHPHVEIKIVDPETGEIVERGTPGEFCTRGYSVMLGYWRED
MAB_4377c|M.abscessus_ATCC_199 ---------AHPHIEIKIVDPNSGETVQRGQSGELCTRGYSVMLGYWNDE
Mb2533c|M.bovis_AF2122/97 ---------VGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDP
Rv2505c|M.tuberculosis_H37Rv ---------VGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDP
MMAR_3852|M.marinum_M ---------VGPHLEIKVVDPATGRIVPRGTAGEFCTRGYSVMSGYWKAP
MUL_4126|M.ulcerans_Agy99 ---------PFADFELRIG-PDTGEVLLRGP---------NVMLGYLDDP
MLBr_02546|M.leprae_Br4923 ---------VVKGVKVKILDDSGKE-VPRGQVGRIFVGNAFPFEGYTGG-
: . : * : **
MAV_5076|M.avium_104 AETADALR-DGWLHSGDLGLVRADGYLELTGRRKELYKSGGELVMPKEIE
TH_2544|M.thermoresistible__bu AETAEALR-GGWLHSGDLGRIRDDGYLEITGRSKELYKSGGELVMPKEIE
MSMEG_5649|M.smegmatis_MC2_155 EKTREAVDADGWMHTGDLAVMREDGYCTIVGRIKDMVIRGGENIYPREIE
Mvan_4008|M.vanbaalenii_PYR-1 DRTREAVDADGWMHTGDLAVMRDDGYCMIVGRIKDMVIRGGENVYPREIE
Mflv_4867|M.gilvum_PYR-GCK EKTAQAIDADGWMHTGDLAVMRPDGYCNIVGRIKDVVIRGGENIYPREIE
MAB_4377c|M.abscessus_ATCC_199 AHTREVLDTDGWMHTGDLAVMRDDGYCTIIGRLKDMVIRGGENIYPREIE
Mb2533c|M.bovis_AF2122/97 QKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIE
Rv2505c|M.tuberculosis_H37Rv QKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIE
MMAR_3852|M.marinum_M ERTAEVIDPEGWMHTGDLALMDECGYVQITGRIKDIVVRGGENISPREIE
MUL_4126|M.ulcerans_Agy99 RATAAAIDADGWLHTGDIGVLDEAGNLRITDRLKDMYICGGFNVYPAEVE
MLBr_02546|M.leprae_Br4923 ---GGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVE
* : :**:. . . : .* .:: ** : * *:*
MAV_5076|M.avium_104 DLLAGHGDISQVFAVGLSDDRWGEIGCVVVVRAPG-ATITEDDVLALCRD
TH_2544|M.thermoresistible__bu DLLAGYDDISQVFAVGLTDERWGEIGCVVVVPAHG-ARITEQEVLDRCRA
MSMEG_5649|M.smegmatis_MC2_155 EFLYTHPDIDDAQVIGVPDERYGEEICAWIRMKPGRPPLDADKVREFASG
Mvan_4008|M.vanbaalenii_PYR-1 EFLHTHPDIDDVQVIGVPDERYGEEICAWIKVRAGAAPLDAHAVREFAAG
Mflv_4867|M.gilvum_PYR-GCK EFLYTHPDVEDAHVIGVPDDRYGEEVCAWIRMRPGRTALDAAAVREFATD
MAB_4377c|M.abscessus_ATCC_199 EFLLTHPDIEDVHVVGVPDEKYGEELCAWVRMRPDRVVIDAVAIRAFASG
Mb2533c|M.bovis_AF2122/97 ELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIERLREYCMG
Rv2505c|M.tuberculosis_H37Rv ELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIERLREYCMG
MMAR_3852|M.marinum_M EFLHSHPDIVDAHVVGVPDERMGEELMAVVKLRAGAPELTTGLLREYCAG
MUL_4126|M.ulcerans_Agy99 QVLARLDGVADVAVIGIPDHRLGEVGRAFIVARPG-FNLDEKSVIDYTRE
MLBr_02546|M.leprae_Br4923 DLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQD-ATIDEDAIKAYVRD
:.: : : .:*: * . * . : . : :
MAV_5076|M.avium_104 KLARFKVPKRVVFYRSEDLPTTPTGKVQKFRLAEQLRSADAVTGAERLPA
TH_2544|M.thermoresistible__bu RLARFKVPKRVEFLQAAELPTTPTGKVQKFRLVERFTRRG----------
MSMEG_5649|M.smegmatis_MC2_155 KLAHYKIPRYVHVVD--EFPMTVTGKIRKVQMREETVALLGLEA------
Mvan_4008|M.vanbaalenii_PYR-1 KLAHYKIPRYVHMTD--DFPMTVTGKVRKIDMRAETVRILGL--------
Mflv_4867|M.gilvum_PYR-GCK KLAHYKIPRYVHVVD--EFPMTVTGKIRKVEMREVSARLLGL--------
MAB_4377c|M.abscessus_ATCC_199 RLAHYKIPRYVHVVE--SFPMTVTGKVRKIEMRQQTIQIFGLPEPGRTDE
Mb2533c|M.bovis_AF2122/97 RIARFKIPRYLWIVD--EFPMTVTGKVRKVEMRQQALEYLRGQQ------
Rv2505c|M.tuberculosis_H37Rv RIARFKIPRYLWIVD--EFPMTVTGKVRKVEMRQQALEYLRGQQ------
MMAR_3852|M.marinum_M QIAKFKIPRYLRLVD--EFPMTVTGKVRKVEMRQQAIEYLRGQH------
MUL_4126|M.ulcerans_Agy99 HLANFKAPRSVRFVD--TLPRNAGGKVVKPQLRELA--------------
MLBr_02546|M.leprae_Br4923 HLARYKVPREVIFLE--ELPRNPTGKVLKRELRDFEVH------------
::*.:* *: : . :* . **: * :
MAV_5076|M.avium_104 GTS
TH_2544|M.thermoresistible__bu ---
MSMEG_5649|M.smegmatis_MC2_155 ---
Mvan_4008|M.vanbaalenii_PYR-1 ---
Mflv_4867|M.gilvum_PYR-GCK ---
MAB_4377c|M.abscessus_ATCC_199 Q--
Mb2533c|M.bovis_AF2122/97 ---
Rv2505c|M.tuberculosis_H37Rv ---
MMAR_3852|M.marinum_M ---
MUL_4126|M.ulcerans_Agy99 ---
MLBr_02546|M.leprae_Br4923 ---