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TDTLTLRLPFGEVIVQAWTLLKVTALPAVLMAIPFGAMVAVQLSGLVNEVGANSLVGSATGVAVLRQGAP VTAGLLMGGAAASAIASDFGARAIREELDALKTLGIDPVRRLVVPRFLGLLLITPSLVVIVIAMGVGAAF VIATVVNGVTPGSFWLSFGSFAKMVDLWFTMGKGFIFAGIVAVISSQRGMEAKGGPRGVADAVNASVVLN VIFIVVVNLAITQLQTMFFPMAVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5054 | - | - | 100% (235) | ABC transporter integral membrane protein |
| M. avium 104 | MAV_2390 | - | 1e-46 | 40.17% (229) | hypothetical protein MAV_2390 |
| M. avium 104 | MAV_0655 | - | 6e-41 | 38.14% (215) | hypothetical protein MAV_0655 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3531c | yrbE4A | 8e-40 | 37.67% (215) | integral membrane protein YrbE4a |
| M. gilvum PYR-GCK | Mflv_0012 | - | 5e-49 | 41.92% (229) | hypothetical protein Mflv_0012 |
| M. tuberculosis H37Rv | Rv3501c | yrbE4A | 8e-40 | 37.67% (215) | integral membrane protein YrbE4a |
| M. leprae Br4923 | MLBr_02587 | yrbE1A | 2e-34 | 32.03% (231) | hypothetical protein MLBr_02587 |
| M. abscessus ATCC 19977 | MAB_4028 | - | 2e-63 | 46.15% (234) | putative YrbE family protein |
| M. marinum M | MMAR_3862 | yrbE5A | 4e-48 | 40.17% (229) | YrbE family protein, YrbE5A |
| M. smegmatis MC2 155 | MSMEG_1141 | - | 2e-48 | 42.17% (230) | ABC-transporter integral membrane protein |
| M. thermoresistible (build 8) | TH_2930 | - | 7e-49 | 41.48% (229) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_3794 | yrbE5A | 8e-48 | 39.74% (229) | YrbE family protein, YrbE5A |
| M. vanbaalenii PYR-1 | Mvan_0957 | - | 1e-48 | 42.36% (229) | hypothetical protein Mvan_0957 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5054|M.avium_104 --------------------------------------------------
MAB_4028|M.abscessus_ATCC_1997 MSHVAADARLEPAADDWTETPDVESGSKSEDDHTSDPAAGALPQLLDRAP
Mflv_0012|M.gilvum_PYR-GCK -MRLPGPRTRCGRRHRRSECTAAERTSGMTTADQPVRRDDSVHAVQDWVG
Mvan_0957|M.vanbaalenii_PYR-1 ----------------------------MSSDTK----GEGVGVITDWAG
MSMEG_1141|M.smegmatis_MC2_155 ------------------MTTSPDRVSDGGAPER------GTDAIEKWAT
TH_2930|M.thermoresistible__bu ----------------------------MTRSDG-------VEVIGEWAG
MMAR_3862|M.marinum_M ------------------MTTQPEPALLGSRNDD------GVAAIGDWAA
MUL_3794|M.ulcerans_Agy99 ------------------MTTQPEPALLGSRNDD------GVAAIGDWAA
Mb3531c|M.bovis_AF2122/97 --------------------------------------------------
Rv3501c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02587|M.leprae_Br4923 -------------------------------------------MTTETRS
MAV_5054|M.avium_104 -----------------------------------MTDTLTLRLPFGEVI
MAB_4028|M.abscessus_ATCC_1997 RLIKRPVAYAVSQTDSMLKTLGRYVDLVVQSFAFLISDIVRLRHPWQDTV
Mflv_0012|M.gilvum_PYR-GCK GYVRR-------HPLASLATVGDQFVLGVRTLQWFFVDLFTGRFQFQEFV
Mvan_0957|M.vanbaalenii_PYR-1 GYVKR-------HPLASLTTVGDQFVLGVRTVQYFLLDLFSGRFQWQEFI
MSMEG_1141|M.smegmatis_MC2_155 GYVRR-------HPIASLTTVGDQFVLGVRTVQYLFTELFTGRFQWQEFI
TH_2930|M.thermoresistible__bu GYIRR-------HPLAALGTVGEQFVLGVRTLQYLFVDLFTGRFQWWEFV
MMAR_3862|M.marinum_M GYVRR-------HPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFV
MUL_3794|M.ulcerans_Agy99 GYIRR-------HPLAALTTVGEQFVLGVRTIQYFFVDLVTGRFQWQEFV
Mb3531c|M.bovis_AF2122/97 -------------MIQQLAVPARAVGGFFEMSMDTARAAFRRPFQFREFL
Rv3501c|M.tuberculosis_H37Rv -------------MIQQLAVPARAVGGFFEMSMDTARAAFRRPFQFREFL
MLBr_02587|M.leprae_Br4923 SLVEY--------AHTKLQTPLVLVGGFFRMLVLTGKALFRRPFQWREFI
. : : :
MAV_5054|M.avium_104 VQAWTLLKVTALPAVLMAIPFGAMVAVQLSGLVNEVGANSLVGSATGVAV
MAB_4028|M.abscessus_ATCC_1997 IQSWFILTVTVVPAILVSIPFGVIVAVQAGSIISQVGASSISGAAGGLGV
Mflv_0012|M.gilvum_PYR-GCK RQGAFMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAV
Mvan_0957|M.vanbaalenii_PYR-1 RQGAFMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAV
MSMEG_1141|M.smegmatis_MC2_155 RQGAFMASTAVVPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAV
TH_2930|M.thermoresistible__bu RQAAFMAGTAVLPTVLVALPIGVTLSIQFALLAGQVGATSLAGAASGLAV
MMAR_3862|M.marinum_M RQGAFMAGTAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAV
MUL_3794|M.ulcerans_Agy99 RQGAFMAGTAVLPTILVSLPISVTLSIQFALLAGQVGATSLAGAASGLAV
Mb3531c|M.bovis_AF2122/97 DQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGT
Rv3501c|M.tuberculosis_H37Rv DQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGT
MLBr_02587|M.leprae_Br4923 LQCWFIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGA
* : .: :*::::::*: . : . : :..* .: *:. ....
MAV_5054|M.avium_104 LRQGAPVTAGLLMGGAAASAIASDFGARAIREELDALKTLGIDPVRRLVV
MAB_4028|M.abscessus_ATCC_1997 IQQGAPIVAALLLGGAAGSAVATDLGARSIREEVDAMRVMGVNPVQRLVT
Mflv_0012|M.gilvum_PYR-GCK IRQAASLTAAILMAAAVGSAITADLGSRKMREETDAMEVMGVSVIRRLVV
Mvan_0957|M.vanbaalenii_PYR-1 IRQAASLTAAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVV
MSMEG_1141|M.smegmatis_MC2_155 IRQAASLTAAVLMAAAVGSAITADLGSRKMREETDAMEVMGVSVIKRLVV
TH_2930|M.thermoresistible__bu IRQAASLTAAILMAAAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVV
MMAR_3862|M.marinum_M IRQGASLVAAVLMASAVGSAITADLGSRTMREETDAMEVMGVSVIRRLVV
MUL_3794|M.ulcerans_Agy99 IRQGASLVAAVLMASAVGSAITADLGSRTMREETDAMEVMGLSVIRRLVV
Mb3531c|M.bovis_AF2122/97 ITQLGPVVTVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVV
Rv3501c|M.tuberculosis_H37Rv ITQLGPVVTVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVV
MLBr_02587|M.leprae_Br4923 VTQLGPLTTVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVV
: * ..:.: :::..* .::: :*:*:* :*** **:..:*:. ::***.
MAV_5054|M.avium_104 PRFLGLLLITPSLVVIVIAMGVGAAFVIATVVNGVTPGSFWLSFGSFAKM
MAB_4028|M.abscessus_ATCC_1997 PRLAAILFVSPLLCIFIIFVGIFAGYLVNVGFQGGTPGSYLSSFAAFANV
Mflv_0012|M.gilvum_PYR-GCK PRFAAAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATT
Mvan_0957|M.vanbaalenii_PYR-1 PRFAAAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFATT
MSMEG_1141|M.smegmatis_MC2_155 PRFAAAIMIGVALTGVVCFVGFIASFLFNVYFQDGAPGSFVATFASFATT
TH_2930|M.thermoresistible__bu PRFAAAIMIGVALTGVVCFVGFLASYLFNVYFQNGAPGSFVATFASFTTT
MMAR_3862|M.marinum_M PRFAAAIMIGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATT
MUL_3794|M.ulcerans_Agy99 PRFAAAIMIGVALTGVVCFVGFFASYMFNVYFQNGAPGSFVATFASFATT
Mb3531c|M.bovis_AF2122/97 PRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGL
Rv3501c|M.tuberculosis_H37Rv PRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGL
MLBr_02587|M.leprae_Br4923 PRVLAATLVATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGL
**. . :: * .: :*. ..: . . .:. *:: : ::
MAV_5054|M.avium_104 VDLWFTMGKGFIFAGIVAVISSQRGMEAKGGPRGVADAVNASVVLNVIFI
MAB_4028|M.abscessus_ATCC_1997 SDVTVAVLKTWLFGVVVILVACQRGLEAKGGARGVADAVNATVVIGVVTV
Mflv_0012|M.gilvum_PYR-GCK GDMIVALVKAVIFGAIVAIVSCQKGLSTQGGPTGVANSVNAAVVESILVL
Mvan_0957|M.vanbaalenii_PYR-1 GDMIVALVKAVIFGAIVAVVSCQKGLATQGGPTGVANSVNAAVVESILLL
MSMEG_1141|M.smegmatis_MC2_155 GDMIVALIKAVIFGAIVAVVSCQKGLSTVGGPTGVANSVNAAVVESILLL
TH_2930|M.thermoresistible__bu GDMLVALIKAVVFGAIVAVVSCQKGLSTKGGPTGVANSVNAAVVESILVL
MMAR_3862|M.marinum_M DDMFLALFKAVIFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVL
MUL_3794|M.ulcerans_Agy99 DDMFLALFKAVMFGAIVAVVSAQKGLSTKGGPTGVANSVNAAVVESILVL
Mb3531c|M.bovis_AF2122/97 RELILAEIKALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICL
Rv3501c|M.tuberculosis_H37Rv RELILAEIKALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICL
MLBr_02587|M.leprae_Br4923 PEVVIATVKAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVAL
:: .: * *. :. ::.. :*: . **. *:. :** :** .: :
MAV_5054|M.avium_104 VVVNLAITQLQTMFFPMAVA
MAB_4028|M.abscessus_ATCC_1997 MVLNTVITQIVAMFMPSKVG
Mflv_0012|M.gilvum_PYR-GCK MVVNVAISQLYILMFPRVGL
Mvan_0957|M.vanbaalenii_PYR-1 MVVNVAISQLYIMMFPRVGL
MSMEG_1141|M.smegmatis_MC2_155 MVVNVAISQLYIMLFPRVGL
TH_2930|M.thermoresistible__bu MIVNVGISQLYIMLFPRVGL
MMAR_3862|M.marinum_M MIVNVSISQLHVMLAPRTGL
MUL_3794|M.ulcerans_Agy99 MIVNVSISQLHVMLAPRTGL
Mb3531c|M.bovis_AF2122/97 FVINVVMTAIGVRISAQ---
Rv3501c|M.tuberculosis_H37Rv FVINVVMTAIGVRISAQ---
MLBr_02587|M.leprae_Br4923 YAVNVVLTTIGVRFGTGH--
:* :: : : .